Result of FASTA (ccds) for
pF1KB8228
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB8228, 409 aa
1>>>pF1KB8228 409 - 409 aa - 409 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 7.1038+/-0.000759; mu= 10.4181+/- 0.046
mean_var=137.1480+/-27.933, 0's: 0 Z-trim(113.2): 25 B-trim: 781 in 1/50
Lambda= 0.109516
statistics sampled from 13868 (13884) to 13868 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.768), E-opt: 0.2 (0.426), width: 16
Scan time: 2.500
The best scores are: opt bits E(32554)
CCDS945.1 PLEKHO1 gene_id:51177|Hs108|chr1 ( 409) 2698 437.3 1.2e-122
CCDS76210.1 PLEKHO1 gene_id:51177|Hs108|chr1 ( 226) 1477 244.2 9.3e-65
CCDS10196.1 PLEKHO2 gene_id:80301|Hs108|chr15 ( 490) 409 75.7 1.1e-13
CCDS73739.1 PLEKHO2 gene_id:80301|Hs108|chr15 ( 440) 363 68.4 1.5e-11
>>CCDS945.1 PLEKHO1 gene_id:51177|Hs108|chr1 (409 aa)
initn: 2698 init1: 2698 opt: 2698 Z-score: 2315.1 bits: 437.3 E(32554): 1.2e-122
Smith-Waterman score: 2698; 100.0% identity (100.0% similar) in 409 aa overlap (1-409:1-409)
10 20 30 40 50 60
pF1KB8 MMKKNNSAKRGPQDGNQQPAPPEKVGWVRKFCGKGIFREIWKNRYVVLKGDQLYISEKEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS94 MMKKNNSAKRGPQDGNQQPAPPEKVGWVRKFCGKGIFREIWKNRYVVLKGDQLYISEKEV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 KDEKNIQEVFDLSDYEKCEELRKSKSRSKKNHSKFTLAHSKQPGNTAPNLIFLAVSPEEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS94 KDEKNIQEVFDLSDYEKCEELRKSKSRSKKNHSKFTLAHSKQPGNTAPNLIFLAVSPEEK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 ESWINALNSAITRAKNRILDEVTVEEDSYLAHPTRDRAKIQHSRRPPTRGHLMAVASTST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS94 ESWINALNSAITRAKNRILDEVTVEEDSYLAHPTRDRAKIQHSRRPPTRGHLMAVASTST
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 SDGMLTLDLIQEEDPSPEEPTSCAESFRVDLDKSVAQLAGSRRRADSDRIQPSADRASSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS94 SDGMLTLDLIQEEDPSPEEPTSCAESFRVDLDKSVAQLAGSRRRADSDRIQPSADRASSL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 SRPWEKTDKGATYTPQAPKKLTPTEKGRCASLEEILSQRDAASARTLQLRAEEPPTPALP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS94 SRPWEKTDKGATYTPQAPKKLTPTEKGRCASLEEILSQRDAASARTLQLRAEEPPTPALP
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB8 NPGQLSRIQDLVARKLEETQELLAEVQGLGDGKRKAKDPPRSPPDSESEQLLLETERLLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS94 NPGQLSRIQDLVARKLEETQELLAEVQGLGDGKRKAKDPPRSPPDSESEQLLLETERLLG
310 320 330 340 350 360
370 380 390 400
pF1KB8 EASSNWSQAKRVLQEVRELRDLYRQMDLQTPDSHLRQTTPHSQYRKSLM
:::::::::::::::::::::::::::::::::::::::::::::::::
CCDS94 EASSNWSQAKRVLQEVRELRDLYRQMDLQTPDSHLRQTTPHSQYRKSLM
370 380 390 400
>>CCDS76210.1 PLEKHO1 gene_id:51177|Hs108|chr1 (226 aa)
initn: 1477 init1: 1477 opt: 1477 Z-score: 1276.1 bits: 244.2 E(32554): 9.3e-65
Smith-Waterman score: 1477; 100.0% identity (100.0% similar) in 226 aa overlap (184-409:1-226)
160 170 180 190 200 210
pF1KB8 TRDRAKIQHSRRPPTRGHLMAVASTSTSDGMLTLDLIQEEDPSPEEPTSCAESFRVDLDK
::::::::::::::::::::::::::::::
CCDS76 MLTLDLIQEEDPSPEEPTSCAESFRVDLDK
10 20 30
220 230 240 250 260 270
pF1KB8 SVAQLAGSRRRADSDRIQPSADRASSLSRPWEKTDKGATYTPQAPKKLTPTEKGRCASLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS76 SVAQLAGSRRRADSDRIQPSADRASSLSRPWEKTDKGATYTPQAPKKLTPTEKGRCASLE
40 50 60 70 80 90
280 290 300 310 320 330
pF1KB8 EILSQRDAASARTLQLRAEEPPTPALPNPGQLSRIQDLVARKLEETQELLAEVQGLGDGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS76 EILSQRDAASARTLQLRAEEPPTPALPNPGQLSRIQDLVARKLEETQELLAEVQGLGDGK
100 110 120 130 140 150
340 350 360 370 380 390
pF1KB8 RKAKDPPRSPPDSESEQLLLETERLLGEASSNWSQAKRVLQEVRELRDLYRQMDLQTPDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS76 RKAKDPPRSPPDSESEQLLLETERLLGEASSNWSQAKRVLQEVRELRDLYRQMDLQTPDS
160 170 180 190 200 210
400
pF1KB8 HLRQTTPHSQYRKSLM
::::::::::::::::
CCDS76 HLRQTTPHSQYRKSLM
220
>>CCDS10196.1 PLEKHO2 gene_id:80301|Hs108|chr15 (490 aa)
initn: 490 init1: 258 opt: 409 Z-score: 359.4 bits: 75.7 E(32554): 1.1e-13
Smith-Waterman score: 485; 33.8% identity (59.4% similar) in 352 aa overlap (9-351:3-321)
10 20 30 40 50
pF1KB8 MMKKNNSAKRGPQDGNQQPAPPE---KVGWVRKFCGKGIFREIWKNRYVVLKGDQLYISE
..: ......: . :.::..: : :.. .::.::..: :: . :
CCDS10 MEEEGVKEAGEKPRGAQMVDKAGWIKKSSG-GLLG-FWKDRYLLLCQAQLLVYE
10 20 30 40 50
60 70 80 90 100 110
pF1KB8 KEVKDEKNIQEVFDLSDYEKCEELRKSKSRSKKNHSKFTLAHSKQPGNTAPNLIFLAVSP
.: :.: .. : .:..::::..:: . :..: .: : .: ::: . .. : : .
CCDS10 NE-DDQKCVETV-ELGSYEKCQDLR---ALLKRKH-RFILLRS--PGNKVSDIKFQAPTG
60 70 80 90 100
120 130 140 150 160 170
pF1KB8 EEKESWINALNSAITRAKNRILDEVTVEEDSYLAHPTRDRAKIQHSRRPPTRGHLMAVAS
:::::::.::: .:.:.::. .::: :... : : ::::.. . :::::: :: :::
CCDS10 EEKESWIKALNEGINRGKNKAFDEVKVDKSCALEHVTRDRVRGGQRRRPPTRVHLKEVAS
110 120 130 140 150 160
180 190 200 210 220 230
pF1KB8 TSTSDGMLTLDLIQEEDPSPEEPTSCAESFRVDLDKSVAQLAGSRRRADSDRIQPSADR-
.. :::.: ::: : : : : .: : :: :.. . :.
CCDS10 AA-SDGLLRLDL----DVPDSGPPVFAPSNHV----SEAQ----PRETPRPLMPPTKPFL
170 180 190 200 210
240 250 260 270 280 290
pF1KB8 ASSLSRPWEKTDKGATYTPQAPKKLTPTEKGRCASLEEILSQRDAASARTLQLRAEEPPT
: . : .... :: . . ::. . .: : ::.:. . . .:.::.
CCDS10 APETTSPGDRVE-----TPVGERAPTPVSASSEVSPE---SQEDSETPAEEDSGSEQPPN
220 230 240 250 260
300 310 320 330 340 350
pF1KB8 PALPNPGQLS----RIQDL-VARKLEETQELLAEVQGLGDGKRKAKDPPRSPPDSESEQL
.::. ..: :. .:.. : .: .:.. . :.. :: :: ::.:
CCDS10 SVLPDKLKVSWENPSPQEAPAAESAEPSQAPCSETSEAAP--REGGKPPTPPPKILSEKL
270 280 290 300 310 320
360 370 380 390 400
pF1KB8 LLETERLLGEASSNWSQAKRVLQEVRELRDLYRQMDLQTPDSHLRQTTPHSQYRKSLM
CCDS10 KASMGEMQASGPPAPGTVQVSVNGMDDSPEPAKPSQAEGTPGTPPKDATTSTALPPWDLP
330 340 350 360 370 380
>>CCDS73739.1 PLEKHO2 gene_id:80301|Hs108|chr15 (440 aa)
initn: 441 init1: 258 opt: 363 Z-score: 320.8 bits: 68.4 E(32554): 1.5e-11
Smith-Waterman score: 404; 34.1% identity (58.2% similar) in 299 aa overlap (59-351:2-271)
30 40 50 60 70 80
pF1KB8 RKFCGKGIFREIWKNRYVVLKGDQLYISEKEVKDEKNIQEVFDLSDYEKCEELRKSKSRS
: .:... :. .:..::::..:: .
CCDS73 MEEEDDQKCVETVELGSYEKCQDLR---ALL
10 20
90 100 110 120 130 140
pF1KB8 KKNHSKFTLAHSKQPGNTAPNLIFLAVSPEEKESWINALNSAITRAKNRILDEVTVEEDS
:..: .: : .: ::: . .. : : . :::::::.::: .:.:.::. .::: :...
CCDS73 KRKH-RFILLRS--PGNKVSDIKFQAPTGEEKESWIKALNEGINRGKNKAFDEVKVDKSC
30 40 50 60 70 80
150 160 170 180 190 200
pF1KB8 YLAHPTRDRAKIQHSRRPPTRGHLMAVASTSTSDGMLTLDLIQEEDPSPEEPTSCAESFR
: : ::::.. . :::::: :: ::: ..:::.: ::: : : : : .
CCDS73 ALEHVTRDRVRGGQRRRPPTRVHLKEVAS-AASDGLLRLDL----DVPDSGPPVFAPSNH
90 100 110 120 130 140
210 220 230 240 250 260
pF1KB8 VDLDKSVAQLAGSRRRADSDRIQPSADR-ASSLSRPWEKTDKGATYTPQAPKKLTPTEKG
: : :: :.. . :. : . : .... :: . . ::. .
CCDS73 V----SEAQ----PRETPRPLMPPTKPFLAPETTSPGDRVE-----TPVGERAPTPVSAS
150 160 170 180
270 280 290 300 310 320
pF1KB8 RCASLEEILSQRDAASARTLQLRAEEPPTPALPNPGQLS----RIQDL-VARKLEETQEL
.: : ::.:. . . .:.::. .::. ..: :. .:.. : .:
CCDS73 SEVSPE---SQEDSETPAEEDSGSEQPPNSVLPDKLKVSWENPSPQEAPAAESAEPSQAP
190 200 210 220 230 240
330 340 350 360 370 380
pF1KB8 LAEVQGLGDGKRKAKDPPRSPPDSESEQLLLETERLLGEASSNWSQAKRVLQEVRELRDL
.:.. . :.. :: :: ::.:
CCDS73 CSETSEAA--PREGGKPPTPPPKILSEKLKASMGEMQASGPPAPGTVQVSVNGMDDSPEP
250 260 270 280 290 300
409 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 10:45:37 2016 done: Fri Nov 4 10:45:38 2016
Total Scan time: 2.500 Total Display time: 0.000
Function used was FASTA [36.3.4 Apr, 2011]