FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB8230, 346 aa 1>>>pF1KB8230 346 - 346 aa - 346 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 8.3615+/-0.000341; mu= 4.8677+/- 0.021 mean_var=213.5339+/-43.540, 0's: 0 Z-trim(121.6): 65 B-trim: 0 in 0/56 Lambda= 0.087769 statistics sampled from 38325 (38390) to 38325 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.759), E-opt: 0.2 (0.45), width: 16 Scan time: 6.220 The best scores are: opt bits E(85289) NP_006549 (OMIM: 610421) KH domain-containing, RNA ( 346) 2333 307.5 2.8e-83 XP_011515098 (OMIM: 610421) PREDICTED: KH domain-c ( 346) 2156 285.0 1.6e-76 XP_011515099 (OMIM: 610421) PREDICTED: KH domain-c ( 319) 2146 283.8 3.6e-76 XP_005250814 (OMIM: 610421) PREDICTED: KH domain-c ( 318) 2145 283.6 3.9e-76 XP_005250815 (OMIM: 610421) PREDICTED: KH domain-c ( 302) 1979 262.6 8e-70 XP_011515100 (OMIM: 610421) PREDICTED: KH domain-c ( 303) 1795 239.3 8.3e-63 NP_689901 (OMIM: 610487) KH domain-containing, RNA ( 349) 1505 202.6 1e-51 XP_011515101 (OMIM: 610421) PREDICTED: KH domain-c ( 252) 1326 179.8 5.5e-45 XP_016865834 (OMIM: 610487) PREDICTED: KH domain-c ( 299) 1283 174.4 2.7e-43 XP_016865832 (OMIM: 610487) PREDICTED: KH domain-c ( 305) 1283 174.5 2.7e-43 NP_006550 (OMIM: 602489) KH domain-containing, RNA ( 443) 1273 173.3 8.7e-43 XP_011533818 (OMIM: 610487) PREDICTED: KH domain-c ( 322) 1171 160.3 5.3e-39 XP_016865830 (OMIM: 610487) PREDICTED: KH domain-c ( 322) 1171 160.3 5.3e-39 XP_016865831 (OMIM: 610487) PREDICTED: KH domain-c ( 316) 1170 160.2 5.7e-39 XP_016865826 (OMIM: 610487) PREDICTED: KH domain-c ( 366) 1170 160.2 6.4e-39 XP_011533822 (OMIM: 610487) PREDICTED: KH domain-c ( 285) 1156 158.3 1.8e-38 XP_016865828 (OMIM: 610487) PREDICTED: KH domain-c ( 362) 1155 158.3 2.4e-38 XP_016865829 (OMIM: 610487) PREDICTED: KH domain-c ( 362) 1155 158.3 2.4e-38 XP_016865825 (OMIM: 610487) PREDICTED: KH domain-c ( 367) 1155 158.3 2.4e-38 XP_016865823 (OMIM: 610487) PREDICTED: KH domain-c ( 413) 1155 158.4 2.6e-38 XP_011533821 (OMIM: 610487) PREDICTED: KH domain-c ( 302) 1152 157.9 2.7e-38 XP_011533819 (OMIM: 610487) PREDICTED: KH domain-c ( 320) 1152 157.9 2.8e-38 XP_011533817 (OMIM: 610487) PREDICTED: KH domain-c ( 324) 1152 157.9 2.8e-38 XP_016865824 (OMIM: 610487) PREDICTED: KH domain-c ( 381) 1152 158.0 3.2e-38 XP_016865836 (OMIM: 610487) PREDICTED: KH domain-c ( 251) 1031 142.5 9.6e-34 XP_016865837 (OMIM: 610487) PREDICTED: KH domain-c ( 180) 847 119.0 7.7e-27 NP_001258807 (OMIM: 602489) KH domain-containing, ( 404) 748 106.8 8.3e-23 XP_016865833 (OMIM: 610487) PREDICTED: KH domain-c ( 300) 662 95.8 1.3e-19 XP_016865827 (OMIM: 610487) PREDICTED: KH domain-c ( 364) 578 85.3 2.3e-16 NP_996737 (OMIM: 609590) protein quaking isoform 4 ( 319) 479 72.7 1.3e-12 NP_996735 (OMIM: 609590) protein quaking isoform 2 ( 319) 479 72.7 1.3e-12 NP_996736 (OMIM: 609590) protein quaking isoform 3 ( 325) 479 72.7 1.3e-12 XP_016866991 (OMIM: 609590) PREDICTED: protein qua ( 337) 479 72.7 1.3e-12 NP_006766 (OMIM: 609590) protein quaking isoform 1 ( 341) 479 72.7 1.3e-12 XP_016866992 (OMIM: 609590) PREDICTED: protein qua ( 318) 466 71.0 3.9e-12 XP_011534560 (OMIM: 609590) PREDICTED: protein qua ( 340) 466 71.0 4.1e-12 XP_016866993 (OMIM: 609590) PREDICTED: protein qua ( 311) 465 70.9 4.2e-12 XP_011534561 (OMIM: 609590) PREDICTED: protein qua ( 317) 465 70.9 4.3e-12 NP_001288014 (OMIM: 609590) protein quaking isofor ( 333) 465 70.9 4.4e-12 XP_011534563 (OMIM: 609590) PREDICTED: protein qua ( 198) 374 59.2 8.9e-09 XP_016865835 (OMIM: 610487) PREDICTED: KH domain-c ( 277) 313 51.6 2.4e-06 XP_011534562 (OMIM: 609590) PREDICTED: protein qua ( 293) 251 43.8 0.00058 NP_001333338 (OMIM: 601516) splicing factor 1 isof ( 433) 250 43.8 0.00084 NP_001333339 (OMIM: 601516) splicing factor 1 isof ( 456) 250 43.8 0.00087 XP_016873739 (OMIM: 601516) PREDICTED: splicing fa ( 524) 250 43.9 0.00097 XP_016873740 (OMIM: 601516) PREDICTED: splicing fa ( 524) 250 43.9 0.00097 XP_016873738 (OMIM: 601516) PREDICTED: splicing fa ( 524) 250 43.9 0.00097 XP_016873735 (OMIM: 601516) PREDICTED: splicing fa ( 542) 250 43.9 0.00099 XP_011543550 (OMIM: 601516) PREDICTED: splicing fa ( 545) 250 43.9 0.001 NP_973727 (OMIM: 601516) splicing factor 1 isoform ( 548) 250 43.9 0.001 >>NP_006549 (OMIM: 610421) KH domain-containing, RNA-bin (346 aa) initn: 2333 init1: 2333 opt: 2333 Z-score: 1616.0 bits: 307.5 E(85289): 2.8e-83 Smith-Waterman score: 2333; 100.0% identity (100.0% similar) in 346 aa overlap (1-346:1-346) 10 20 30 40 50 60 pF1KB8 MEEKYLPELMAEKDSLDPSFTHALRLVNQEIEKFQKGEGKDEEKYIDVVINKNMKLGQKV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 MEEKYLPELMAEKDSLDPSFTHALRLVNQEIEKFQKGEGKDEEKYIDVVINKNMKLGQKV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 LIPVKQFPKFNFVGKLLGPRGNSLKRLQEETLTKMSILGKGSMRDKAKEEELRKSGEAKY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 LIPVKQFPKFNFVGKLLGPRGNSLKRLQEETLTKMSILGKGSMRDKAKEEELRKSGEAKY 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 FHLNDDLHVLIEVFAPPAEAYARMGHALEEIKKFLIPDYNDEIRQAQLQELTYLNGGSEN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 FHLNDDLHVLIEVFAPPAEAYARMGHALEEIKKFLIPDYNDEIRQAQLQELTYLNGGSEN 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 ADVPVVRGKPTLRTRGVPAPAITRGRGGVTARPVGVVVPRGTPTPRGVLSTRGPVSRGRG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 ADVPVVRGKPTLRTRGVPAPAITRGRGGVTARPVGVVVPRGTPTPRGVLSTRGPVSRGRG 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 LLTPRARGVPPTGYRPPPPPPTQETYGEYDYDDGYGTAYDEQSYDSYDNSYSTPAQSGAD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 LLTPRARGVPPTGYRPPPPPPTQETYGEYDYDDGYGTAYDEQSYDSYDNSYSTPAQSGAD 250 260 270 280 290 300 310 320 330 340 pF1KB8 YYDYGHGLSEETYDSYGQEEWTNSRHKAPSARTAKGVYRDQPYGRY :::::::::::::::::::::::::::::::::::::::::::::: NP_006 YYDYGHGLSEETYDSYGQEEWTNSRHKAPSARTAKGVYRDQPYGRY 310 320 330 340 >>XP_011515098 (OMIM: 610421) PREDICTED: KH domain-conta (346 aa) initn: 2156 init1: 2156 opt: 2156 Z-score: 1494.9 bits: 285.0 E(85289): 1.6e-76 Smith-Waterman score: 2156; 99.1% identity (99.4% similar) in 322 aa overlap (25-346:25-346) 10 20 30 40 50 60 pF1KB8 MEEKYLPELMAEKDSLDPSFTHALRLVNQEIEKFQKGEGKDEEKYIDVVINKNMKLGQKV : . :::::::::::::::::::::::::::::::: XP_011 MMIIKATNLRLFRASCFLCILSHPRKILQEIEKFQKGEGKDEEKYIDVVINKNMKLGQKV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 LIPVKQFPKFNFVGKLLGPRGNSLKRLQEETLTKMSILGKGSMRDKAKEEELRKSGEAKY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LIPVKQFPKFNFVGKLLGPRGNSLKRLQEETLTKMSILGKGSMRDKAKEEELRKSGEAKY 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 FHLNDDLHVLIEVFAPPAEAYARMGHALEEIKKFLIPDYNDEIRQAQLQELTYLNGGSEN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FHLNDDLHVLIEVFAPPAEAYARMGHALEEIKKFLIPDYNDEIRQAQLQELTYLNGGSEN 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 ADVPVVRGKPTLRTRGVPAPAITRGRGGVTARPVGVVVPRGTPTPRGVLSTRGPVSRGRG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ADVPVVRGKPTLRTRGVPAPAITRGRGGVTARPVGVVVPRGTPTPRGVLSTRGPVSRGRG 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 LLTPRARGVPPTGYRPPPPPPTQETYGEYDYDDGYGTAYDEQSYDSYDNSYSTPAQSGAD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LLTPRARGVPPTGYRPPPPPPTQETYGEYDYDDGYGTAYDEQSYDSYDNSYSTPAQSGAD 250 260 270 280 290 300 310 320 330 340 pF1KB8 YYDYGHGLSEETYDSYGQEEWTNSRHKAPSARTAKGVYRDQPYGRY :::::::::::::::::::::::::::::::::::::::::::::: XP_011 YYDYGHGLSEETYDSYGQEEWTNSRHKAPSARTAKGVYRDQPYGRY 310 320 330 340 >>XP_011515099 (OMIM: 610421) PREDICTED: KH domain-conta (319 aa) initn: 2146 init1: 2146 opt: 2146 Z-score: 1488.5 bits: 283.8 E(85289): 3.6e-76 Smith-Waterman score: 2146; 99.7% identity (100.0% similar) in 318 aa overlap (29-346:2-319) 10 20 30 40 50 60 pF1KB8 MEEKYLPELMAEKDSLDPSFTHALRLVNQEIEKFQKGEGKDEEKYIDVVINKNMKLGQKV .::::::::::::::::::::::::::::::: XP_011 MHEIEKFQKGEGKDEEKYIDVVINKNMKLGQKV 10 20 30 70 80 90 100 110 120 pF1KB8 LIPVKQFPKFNFVGKLLGPRGNSLKRLQEETLTKMSILGKGSMRDKAKEEELRKSGEAKY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LIPVKQFPKFNFVGKLLGPRGNSLKRLQEETLTKMSILGKGSMRDKAKEEELRKSGEAKY 40 50 60 70 80 90 130 140 150 160 170 180 pF1KB8 FHLNDDLHVLIEVFAPPAEAYARMGHALEEIKKFLIPDYNDEIRQAQLQELTYLNGGSEN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FHLNDDLHVLIEVFAPPAEAYARMGHALEEIKKFLIPDYNDEIRQAQLQELTYLNGGSEN 100 110 120 130 140 150 190 200 210 220 230 240 pF1KB8 ADVPVVRGKPTLRTRGVPAPAITRGRGGVTARPVGVVVPRGTPTPRGVLSTRGPVSRGRG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ADVPVVRGKPTLRTRGVPAPAITRGRGGVTARPVGVVVPRGTPTPRGVLSTRGPVSRGRG 160 170 180 190 200 210 250 260 270 280 290 300 pF1KB8 LLTPRARGVPPTGYRPPPPPPTQETYGEYDYDDGYGTAYDEQSYDSYDNSYSTPAQSGAD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LLTPRARGVPPTGYRPPPPPPTQETYGEYDYDDGYGTAYDEQSYDSYDNSYSTPAQSGAD 220 230 240 250 260 270 310 320 330 340 pF1KB8 YYDYGHGLSEETYDSYGQEEWTNSRHKAPSARTAKGVYRDQPYGRY :::::::::::::::::::::::::::::::::::::::::::::: XP_011 YYDYGHGLSEETYDSYGQEEWTNSRHKAPSARTAKGVYRDQPYGRY 280 290 300 310 >>XP_005250814 (OMIM: 610421) PREDICTED: KH domain-conta (318 aa) initn: 2145 init1: 2145 opt: 2145 Z-score: 1487.8 bits: 283.6 E(85289): 3.9e-76 Smith-Waterman score: 2145; 100.0% identity (100.0% similar) in 317 aa overlap (30-346:2-318) 10 20 30 40 50 60 pF1KB8 MEEKYLPELMAEKDSLDPSFTHALRLVNQEIEKFQKGEGKDEEKYIDVVINKNMKLGQKV ::::::::::::::::::::::::::::::: XP_005 MEIEKFQKGEGKDEEKYIDVVINKNMKLGQKV 10 20 30 70 80 90 100 110 120 pF1KB8 LIPVKQFPKFNFVGKLLGPRGNSLKRLQEETLTKMSILGKGSMRDKAKEEELRKSGEAKY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LIPVKQFPKFNFVGKLLGPRGNSLKRLQEETLTKMSILGKGSMRDKAKEEELRKSGEAKY 40 50 60 70 80 90 130 140 150 160 170 180 pF1KB8 FHLNDDLHVLIEVFAPPAEAYARMGHALEEIKKFLIPDYNDEIRQAQLQELTYLNGGSEN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 FHLNDDLHVLIEVFAPPAEAYARMGHALEEIKKFLIPDYNDEIRQAQLQELTYLNGGSEN 100 110 120 130 140 150 190 200 210 220 230 240 pF1KB8 ADVPVVRGKPTLRTRGVPAPAITRGRGGVTARPVGVVVPRGTPTPRGVLSTRGPVSRGRG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ADVPVVRGKPTLRTRGVPAPAITRGRGGVTARPVGVVVPRGTPTPRGVLSTRGPVSRGRG 160 170 180 190 200 210 250 260 270 280 290 300 pF1KB8 LLTPRARGVPPTGYRPPPPPPTQETYGEYDYDDGYGTAYDEQSYDSYDNSYSTPAQSGAD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LLTPRARGVPPTGYRPPPPPPTQETYGEYDYDDGYGTAYDEQSYDSYDNSYSTPAQSGAD 220 230 240 250 260 270 310 320 330 340 pF1KB8 YYDYGHGLSEETYDSYGQEEWTNSRHKAPSARTAKGVYRDQPYGRY :::::::::::::::::::::::::::::::::::::::::::::: XP_005 YYDYGHGLSEETYDSYGQEEWTNSRHKAPSARTAKGVYRDQPYGRY 280 290 300 310 >>XP_005250815 (OMIM: 610421) PREDICTED: KH domain-conta (302 aa) initn: 1979 init1: 1979 opt: 1979 Z-score: 1374.5 bits: 262.6 E(85289): 8e-70 Smith-Waterman score: 1979; 100.0% identity (100.0% similar) in 296 aa overlap (1-296:1-296) 10 20 30 40 50 60 pF1KB8 MEEKYLPELMAEKDSLDPSFTHALRLVNQEIEKFQKGEGKDEEKYIDVVINKNMKLGQKV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MEEKYLPELMAEKDSLDPSFTHALRLVNQEIEKFQKGEGKDEEKYIDVVINKNMKLGQKV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 LIPVKQFPKFNFVGKLLGPRGNSLKRLQEETLTKMSILGKGSMRDKAKEEELRKSGEAKY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LIPVKQFPKFNFVGKLLGPRGNSLKRLQEETLTKMSILGKGSMRDKAKEEELRKSGEAKY 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 FHLNDDLHVLIEVFAPPAEAYARMGHALEEIKKFLIPDYNDEIRQAQLQELTYLNGGSEN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 FHLNDDLHVLIEVFAPPAEAYARMGHALEEIKKFLIPDYNDEIRQAQLQELTYLNGGSEN 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 ADVPVVRGKPTLRTRGVPAPAITRGRGGVTARPVGVVVPRGTPTPRGVLSTRGPVSRGRG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ADVPVVRGKPTLRTRGVPAPAITRGRGGVTARPVGVVVPRGTPTPRGVLSTRGPVSRGRG 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 LLTPRARGVPPTGYRPPPPPPTQETYGEYDYDDGYGTAYDEQSYDSYDNSYSTPAQSGAD :::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LLTPRARGVPPTGYRPPPPPPTQETYGEYDYDDGYGTAYDEQSYDSYDNSYSTPAQRARR 250 260 270 280 290 300 310 320 330 340 pF1KB8 YYDYGHGLSEETYDSYGQEEWTNSRHKAPSARTAKGVYRDQPYGRY XP_005 VD >>XP_011515100 (OMIM: 610421) PREDICTED: KH domain-conta (303 aa) initn: 1863 init1: 1794 opt: 1795 Z-score: 1248.6 bits: 239.3 E(85289): 8.3e-63 Smith-Waterman score: 1795; 91.7% identity (94.3% similar) in 300 aa overlap (1-300:1-298) 10 20 30 40 50 60 pF1KB8 MEEKYLPELMAEKDSLDPSFTHALRLVNQEIEKFQKGEGKDEEKYIDVVINKNMKLGQKV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MEEKYLPELMAEKDSLDPSFTHALRLVNQEIEKFQKGEGKDEEKYIDVVINKNMKLGQKV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 LIPVKQFPKFNFVGKLLGPRGNSLKRLQEETLTKMSILGKGSMRDKAKEEELRKSGEAKY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LIPVKQFPKFNFVGKLLGPRGNSLKRLQEETLTKMSILGKGSMRDKAKEEELRKSGEAKY 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 FHLNDDLHVLIEVFAPPAEAYARMGHALEEIKKFLIPDYNDEIRQAQLQELTYLNGGSEN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FHLNDDLHVLIEVFAPPAEAYARMGHALEEIKKFLIPDYNDEIRQAQLQELTYLNGGSEN 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 ADVPVVRGKPTLRTRGVPAPAITRGRGGVTARPVGVVVPRGTPTPRGVLSTRGPVSRGRG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ADVPVVRGKPTLRTRGVPAPAITRGRGGVTARPVGVVVPRGTPTPRGVLSTRGPVSRGRG 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 LLTPRARGVPPTGYRPPPPPPTQETYGEYDYDDGYGTAYDEQSYDSYDNSYSTPAQSGAD ::::::::::::::::::::::::::::: .: . : . . .. :: .. :: XP_011 LLTPRARGVPPTGYRPPPPPPTQETYGEYGKKSG--LTQDTRHLQRGQQRASTETSHMAD 250 260 270 280 290 310 320 330 340 pF1KB8 YYDYGHGLSEETYDSYGQEEWTNSRHKAPSARTAKGVYRDQPYGRY XP_011 TDCTV 300 >>NP_689901 (OMIM: 610487) KH domain-containing, RNA-bin (349 aa) initn: 1244 init1: 828 opt: 1505 Z-score: 1049.3 bits: 202.6 E(85289): 1e-51 Smith-Waterman score: 1505; 67.5% identity (84.0% similar) in 357 aa overlap (2-346:3-349) 10 20 30 40 50 pF1KB8 MEEKYLPELMAEKDSLDPSFTHALRLVNQEIEKFQKGEGK--DEEK-YIDVVINKNMKL :::::::::::::::::::.:: ::. .:::::: ..:: :::: :.::. :::.:: NP_689 MEEEKYLPELMAEKDSLDPSFVHASRLLAEEIEKFQGSDGKKEDEEKKYLDVISNKNIKL 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB8 GQKVLIPVKQFPKFNFVGKLLGPRGNSLKRLQEETLTKMSILGKGSMRDKAKEEELRKSG ...:::::::.:::::::::::::::::::::::: .::::::::::::::::::::::: NP_689 SERVLIPVKQYPKFNFVGKLLGPRGNSLKRLQEETGAKMSILGKGSMRDKAKEEELRKSG 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB8 EAKYFHLNDDLHVLIEVFAPPAEAYARMGHALEEIKKFLIPDYNDEIRQAQLQELTYLNG :::: ::.:.:::::::::::.:::.::.::::::::::.::::::::: ::.::.:::: NP_689 EAKYAHLSDELHVLIEVFAPPGEAYSRMSHALEEIKKFLVPDYNDEIRQEQLRELSYLNG 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB8 GSENADVPVVRGKPTLRTRGVP-AP-AITRGRGGVTARPV----GVVVPRGTPTPRGVLS ::.. ::. .: ::. :: : .:::::. : ::..:::. . ::.: NP_689 -SEDSG----RGRG-IRGRGIRIAPTAPSRGRGGAIPPPPPPGRGVLTPRGSTVTRGALP 190 200 210 220 230 240 250 260 270 280 pF1KB8 TRGPVSRGRGLLTPRARGVPPT-GYRPPPPPPTQETYGEYDYDDGYGTAYDEQSYDSYDN . ::.: :. ::::::.: . ::: :::: ..:.: :: :::::: ::.:.:..::: NP_689 V-PPVAR--GVPTPRARGAPTVPGYRAPPPP-AHEAYEEYGYDDGYGGEYDDQTYETYDN 240 250 260 270 280 290 290 300 310 320 330 340 pF1KB8 SYSTPAQSGADYYDYGHGLSEETYDSYGQEEWTNSRH--KAPSARTAKGVYRDQPYGRY ::.: .:: .:::::::.::..::::. :::...: ::: :.:.: ::..::::: NP_689 SYATQTQSVPEYYDYGHGVSEDAYDSYAPEEWATTRSSLKAPPQRSARGGYREHPYGRY 300 310 320 330 340 >>XP_011515101 (OMIM: 610421) PREDICTED: KH domain-conta (252 aa) initn: 1326 init1: 1326 opt: 1326 Z-score: 928.7 bits: 179.8 E(85289): 5.5e-45 Smith-Waterman score: 1326; 100.0% identity (100.0% similar) in 204 aa overlap (1-204:1-204) 10 20 30 40 50 60 pF1KB8 MEEKYLPELMAEKDSLDPSFTHALRLVNQEIEKFQKGEGKDEEKYIDVVINKNMKLGQKV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MEEKYLPELMAEKDSLDPSFTHALRLVNQEIEKFQKGEGKDEEKYIDVVINKNMKLGQKV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 LIPVKQFPKFNFVGKLLGPRGNSLKRLQEETLTKMSILGKGSMRDKAKEEELRKSGEAKY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LIPVKQFPKFNFVGKLLGPRGNSLKRLQEETLTKMSILGKGSMRDKAKEEELRKSGEAKY 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 FHLNDDLHVLIEVFAPPAEAYARMGHALEEIKKFLIPDYNDEIRQAQLQELTYLNGGSEN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FHLNDDLHVLIEVFAPPAEAYARMGHALEEIKKFLIPDYNDEIRQAQLQELTYLNGGSEN 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 ADVPVVRGKPTLRTRGVPAPAITRGRGGVTARPVGVVVPRGTPTPRGVLSTRGPVSRGRG :::::::::::::::::::::::: XP_011 ADVPVVRGKPTLRTRGVPAPAITRIPAQNEYPLQNRVWRIEHIRCCCLGDTVFLTLDLPF 190 200 210 220 230 240 >>XP_016865834 (OMIM: 610487) PREDICTED: KH domain-conta (299 aa) initn: 1200 init1: 815 opt: 1283 Z-score: 898.3 bits: 174.4 E(85289): 2.7e-43 Smith-Waterman score: 1283; 68.9% identity (84.3% similar) in 305 aa overlap (2-296:3-297) 10 20 30 40 50 pF1KB8 MEEKYLPELMAEKDSLDPSFTHALRLVNQEIEKFQKGEGK--DEEK-YIDVVINKNMKL :::::::::::::::::::.:: ::. .:::::: ..:: :::: :.::. :::.:: XP_016 MEEEKYLPELMAEKDSLDPSFVHASRLLAEEIEKFQGSDGKKEDEEKKYLDVISNKNIKL 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB8 GQKVLIPVKQFPKFNFVGKLLGPRGNSLKRLQEETLTKMSILGKGSMRDKAKEEELRKSG ...:::::::.:::::::::::::::::::::::: .::::::::::::::::::::::: XP_016 SERVLIPVKQYPKFNFVGKLLGPRGNSLKRLQEETGAKMSILGKGSMRDKAKEEELRKSG 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB8 EAKYFHLNDDLHVLIEVFAPPAEAYARMGHALEEIKKFLIPDYNDEIRQAQLQELTYLNG :::: ::.:.:::::::::::.:::.::.::::::::::.::::::::: ::.::.:::: XP_016 EAKYAHLSDELHVLIEVFAPPGEAYSRMSHALEEIKKFLVPDYNDEIRQEQLRELSYLNG 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB8 GSENADVPVVRGKPTLRTRGVP-AP-AITRGRGGVTARPV----GVVVPRGTPTPRGVLS ::.. ::. .: ::. :: : .:::::. : ::..:::. . ::.: XP_016 -SEDSG----RGRG-IRGRGIRIAPTAPSRGRGGAIPPPPPPGRGVLTPRGSTVTRGALP 190 200 210 220 230 240 250 260 270 280 pF1KB8 TRGPVSRGRGLLTPRARGVPPT-GYRPPPPPPTQETYGEYDYDDGYGTAYDEQSYDSYDN . ::.:: . ::::::.: . ::: :::: ..:.: :: :::::: ::.:.:..::: XP_016 V-PPVARG--VPTPRARGAPTVPGYRAPPPP-AHEAYEEYGYDDGYGGEYDDQTYETYDN 240 250 260 270 280 290 290 300 310 320 330 340 pF1KB8 SYSTPAQSGADYYDYGHGLSEETYDSYGQEEWTNSRHKAPSARTAKGVYRDQPYGRY ::.: .: XP_016 SYATQTQRY >>XP_016865832 (OMIM: 610487) PREDICTED: KH domain-conta (305 aa) initn: 1200 init1: 815 opt: 1283 Z-score: 898.2 bits: 174.5 E(85289): 2.7e-43 Smith-Waterman score: 1283; 68.9% identity (84.3% similar) in 305 aa overlap (2-296:3-297) 10 20 30 40 50 pF1KB8 MEEKYLPELMAEKDSLDPSFTHALRLVNQEIEKFQKGEGK--DEEK-YIDVVINKNMKL :::::::::::::::::::.:: ::. .:::::: ..:: :::: :.::. :::.:: XP_016 MEEEKYLPELMAEKDSLDPSFVHASRLLAEEIEKFQGSDGKKEDEEKKYLDVISNKNIKL 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB8 GQKVLIPVKQFPKFNFVGKLLGPRGNSLKRLQEETLTKMSILGKGSMRDKAKEEELRKSG ...:::::::.:::::::::::::::::::::::: .::::::::::::::::::::::: XP_016 SERVLIPVKQYPKFNFVGKLLGPRGNSLKRLQEETGAKMSILGKGSMRDKAKEEELRKSG 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB8 EAKYFHLNDDLHVLIEVFAPPAEAYARMGHALEEIKKFLIPDYNDEIRQAQLQELTYLNG :::: ::.:.:::::::::::.:::.::.::::::::::.::::::::: ::.::.:::: XP_016 EAKYAHLSDELHVLIEVFAPPGEAYSRMSHALEEIKKFLVPDYNDEIRQEQLRELSYLNG 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB8 GSENADVPVVRGKPTLRTRGVP-AP-AITRGRGGVTARPV----GVVVPRGTPTPRGVLS ::.. ::. .: ::. :: : .:::::. : ::..:::. . ::.: XP_016 -SEDSG----RGRG-IRGRGIRIAPTAPSRGRGGAIPPPPPPGRGVLTPRGSTVTRGALP 190 200 210 220 230 240 250 260 270 280 pF1KB8 TRGPVSRGRGLLTPRARGVPPT-GYRPPPPPPTQETYGEYDYDDGYGTAYDEQSYDSYDN . ::.:: . ::::::.: . ::: :::: ..:.: :: :::::: ::.:.:..::: XP_016 V-PPVARG--VPTPRARGAPTVPGYRAPPPP-AHEAYEEYGYDDGYGGEYDDQTYETYDN 240 250 260 270 280 290 290 300 310 320 330 340 pF1KB8 SYSTPAQSGADYYDYGHGLSEETYDSYGQEEWTNSRHKAPSARTAKGVYRDQPYGRY ::.: .: XP_016 SYATQTQRTYRVCGQ 300 346 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 10:47:14 2016 done: Fri Nov 4 10:47:15 2016 Total Scan time: 6.220 Total Display time: -0.020 Function used was FASTA [36.3.4 Apr, 2011]