FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB8233, 149 aa 1>>>pF1KB8233 149 - 149 aa - 149 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 8.8716+/-0.000345; mu= -2.6702+/- 0.022 mean_var=224.8548+/-46.008, 0's: 0 Z-trim(121.8): 21 B-trim: 64 in 1/56 Lambda= 0.085531 statistics sampled from 38989 (39010) to 38989 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.778), E-opt: 0.2 (0.457), width: 16 Scan time: 5.580 The best scores are: opt bits E(85289) NP_005554 (OMIM: 151442) stathmin isoform a [Homo ( 149) 928 125.8 2.6e-29 NP_981946 (OMIM: 151442) stathmin isoform a [Homo ( 149) 928 125.8 2.6e-29 NP_981944 (OMIM: 151442) stathmin isoform a [Homo ( 149) 928 125.8 2.6e-29 NP_001138926 (OMIM: 151442) stathmin isoform b [Ho ( 174) 778 107.3 1.1e-23 XP_005251199 (OMIM: 600621) PREDICTED: stathmin-2 ( 174) 610 86.6 1.9e-17 NP_008960 (OMIM: 600621) stathmin-2 isoform 2 [Hom ( 179) 610 86.6 2e-17 NP_001263239 (OMIM: 608362) stathmin-3 isoform 2 [ ( 169) 582 83.1 2.1e-16 NP_056978 (OMIM: 608362) stathmin-3 isoform 1 [Hom ( 180) 582 83.1 2.2e-16 NP_001186143 (OMIM: 600621) stathmin-2 isoform 1 [ ( 187) 560 80.4 1.5e-15 >>NP_005554 (OMIM: 151442) stathmin isoform a [Homo sapi (149 aa) initn: 928 init1: 928 opt: 928 Z-score: 647.1 bits: 125.8 E(85289): 2.6e-29 Smith-Waterman score: 928; 100.0% identity (100.0% similar) in 149 aa overlap (1-149:1-149) 10 20 30 40 50 60 pF1KB8 MASSDIQVKELEKRASGQAFELILSPRSKESVPEFPLSPPKKKDLSLEEIQKKLEAAEER :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 MASSDIQVKELEKRASGQAFELILSPRSKESVPEFPLSPPKKKDLSLEEIQKKLEAAEER 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 RKSHEAEVLKQLAEKREHEKEVLQKAIEENNNFSKMAEEKLTHKMEANKENREAQMAAKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 RKSHEAEVLKQLAEKREHEKEVLQKAIEENNNFSKMAEEKLTHKMEANKENREAQMAAKL 70 80 90 100 110 120 130 140 pF1KB8 ERLREKDKHIEEVRKNKESKDPADETEAD ::::::::::::::::::::::::::::: NP_005 ERLREKDKHIEEVRKNKESKDPADETEAD 130 140 >>NP_981946 (OMIM: 151442) stathmin isoform a [Homo sapi (149 aa) initn: 928 init1: 928 opt: 928 Z-score: 647.1 bits: 125.8 E(85289): 2.6e-29 Smith-Waterman score: 928; 100.0% identity (100.0% similar) in 149 aa overlap (1-149:1-149) 10 20 30 40 50 60 pF1KB8 MASSDIQVKELEKRASGQAFELILSPRSKESVPEFPLSPPKKKDLSLEEIQKKLEAAEER :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_981 MASSDIQVKELEKRASGQAFELILSPRSKESVPEFPLSPPKKKDLSLEEIQKKLEAAEER 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 RKSHEAEVLKQLAEKREHEKEVLQKAIEENNNFSKMAEEKLTHKMEANKENREAQMAAKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_981 RKSHEAEVLKQLAEKREHEKEVLQKAIEENNNFSKMAEEKLTHKMEANKENREAQMAAKL 70 80 90 100 110 120 130 140 pF1KB8 ERLREKDKHIEEVRKNKESKDPADETEAD ::::::::::::::::::::::::::::: NP_981 ERLREKDKHIEEVRKNKESKDPADETEAD 130 140 >>NP_981944 (OMIM: 151442) stathmin isoform a [Homo sapi (149 aa) initn: 928 init1: 928 opt: 928 Z-score: 647.1 bits: 125.8 E(85289): 2.6e-29 Smith-Waterman score: 928; 100.0% identity (100.0% similar) in 149 aa overlap (1-149:1-149) 10 20 30 40 50 60 pF1KB8 MASSDIQVKELEKRASGQAFELILSPRSKESVPEFPLSPPKKKDLSLEEIQKKLEAAEER :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_981 MASSDIQVKELEKRASGQAFELILSPRSKESVPEFPLSPPKKKDLSLEEIQKKLEAAEER 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 RKSHEAEVLKQLAEKREHEKEVLQKAIEENNNFSKMAEEKLTHKMEANKENREAQMAAKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_981 RKSHEAEVLKQLAEKREHEKEVLQKAIEENNNFSKMAEEKLTHKMEANKENREAQMAAKL 70 80 90 100 110 120 130 140 pF1KB8 ERLREKDKHIEEVRKNKESKDPADETEAD ::::::::::::::::::::::::::::: NP_981 ERLREKDKHIEEVRKNKESKDPADETEAD 130 140 >>NP_001138926 (OMIM: 151442) stathmin isoform b [Homo s (174 aa) initn: 778 init1: 778 opt: 778 Z-score: 546.2 bits: 107.3 E(85289): 1.1e-23 Smith-Waterman score: 778; 100.0% identity (100.0% similar) in 126 aa overlap (1-126:1-126) 10 20 30 40 50 60 pF1KB8 MASSDIQVKELEKRASGQAFELILSPRSKESVPEFPLSPPKKKDLSLEEIQKKLEAAEER :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MASSDIQVKELEKRASGQAFELILSPRSKESVPEFPLSPPKKKDLSLEEIQKKLEAAEER 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 RKSHEAEVLKQLAEKREHEKEVLQKAIEENNNFSKMAEEKLTHKMEANKENREAQMAAKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RKSHEAEVLKQLAEKREHEKEVLQKAIEENNNFSKMAEEKLTHKMEANKENREAQMAAKL 70 80 90 100 110 120 130 140 pF1KB8 ERLREKDKHIEEVRKNKESKDPADETEAD :::::: NP_001 ERLREKMYFWTHGPGAHPAQISAEQSCLHSVPALCPALGLQSALITWSDLSHHH 130 140 150 160 170 >>XP_005251199 (OMIM: 600621) PREDICTED: stathmin-2 isof (174 aa) initn: 610 init1: 610 opt: 610 Z-score: 434.2 bits: 86.6 E(85289): 1.9e-17 Smith-Waterman score: 610; 74.6% identity (88.1% similar) in 134 aa overlap (5-138:34-167) 10 20 30 pF1KB8 MASSDIQVKELEKRASGQAFELILSPRSKESVPE :..::...::::::::::::.: : : XP_005 KEKMKELSMLSLICSCFYPEPRNINIYTYDDMEVKQINKRASGQAFELILKPPSPISEAP 10 20 30 40 50 60 40 50 60 70 80 90 pF1KB8 FPLSPPKKKDLSLEEIQKKLEAAEERRKSHEAEVLKQLAEKREHEKEVLQKAIEENNNFS :. ::::::::::::::::::::::::.::.::::::::::::.::::::.::::::: XP_005 RTLASPKKKDLSLEEIQKKLEAAEERRKSQEAQVLKQLAEKREHEREVLQKALEENNNFS 70 80 90 100 110 120 100 110 120 130 140 pF1KB8 KMAEEKLTHKMEANKENREAQMAAKLERLREKDKHIEEVRKNKESKDPADETEAD ::::::: ::: ::::::..:: .:::.::..: :::.::: XP_005 KMAEEKLILKMEQIKENREANLAAIIERLQEKERHAAEVRRNKELQVELSG 130 140 150 160 170 >>NP_008960 (OMIM: 600621) stathmin-2 isoform 2 [Homo sa (179 aa) initn: 610 init1: 610 opt: 610 Z-score: 434.0 bits: 86.6 E(85289): 2e-17 Smith-Waterman score: 610; 74.6% identity (88.1% similar) in 134 aa overlap (5-138:39-172) 10 20 30 pF1KB8 MASSDIQVKELEKRASGQAFELILSPRSKESVPE :..::...::::::::::::.: : : NP_008 KEKMKELSMLSLICSCFYPEPRNINIYTYDDMEVKQINKRASGQAFELILKPPSPISEAP 10 20 30 40 50 60 40 50 60 70 80 90 pF1KB8 FPLSPPKKKDLSLEEIQKKLEAAEERRKSHEAEVLKQLAEKREHEKEVLQKAIEENNNFS :. ::::::::::::::::::::::::.::.::::::::::::.::::::.::::::: NP_008 RTLASPKKKDLSLEEIQKKLEAAEERRKSQEAQVLKQLAEKREHEREVLQKALEENNNFS 70 80 90 100 110 120 100 110 120 130 140 pF1KB8 KMAEEKLTHKMEANKENREAQMAAKLERLREKDKHIEEVRKNKESKDPADETEAD ::::::: ::: ::::::..:: .:::.::..: :::.::: NP_008 KMAEEKLILKMEQIKENREANLAAIIERLQEKERHAAEVRRNKELQVELSG 130 140 150 160 170 >>NP_001263239 (OMIM: 608362) stathmin-3 isoform 2 [Homo (169 aa) initn: 636 init1: 484 opt: 582 Z-score: 415.7 bits: 83.1 E(85289): 2.1e-16 Smith-Waterman score: 582; 67.6% identity (88.5% similar) in 139 aa overlap (5-141:28-165) 10 20 30 pF1KB8 MASSDIQVKELEKRASGQAFELILSPRSKESVPEFPL :..::.:.::::::.::.::. : : :: :. NP_001 MKELSVLSLICSCFYTQPHPNTVYQYGDMEVKQLDKRASGQSFEVILKSPSDLS-PESPM 10 20 30 40 50 40 50 60 70 80 90 pF1KB8 --SPPKKKDLSLEEIQKKLEAAEERRKSHEAEVLKQLAEKREHEKEVLQKAIEENNNFSK ::::::: ::::.::.:::::::::..::.:::::::.::::.:::.::.:::::::. NP_001 LSSPPKKKDTSLEELQKRLEAAEERRKTQEAQVLKQLAERREHEREVLHKALEENNNFSR 60 70 80 90 100 110 100 110 120 130 140 pF1KB8 MAEEKLTHKMEANKENREAQMAAKLERLREKDKHIEEVRKNKESKDPADETEAD .:::::..::: .:: :::..:: ::::::. : :::.:::... NP_001 QAEEKLNYKMELSKEIREAHLAALRERLREKELHAAEVRRNKEQREEMSG 120 130 140 150 160 >>NP_056978 (OMIM: 608362) stathmin-3 isoform 1 [Homo sa (180 aa) initn: 636 init1: 484 opt: 582 Z-score: 415.3 bits: 83.1 E(85289): 2.2e-16 Smith-Waterman score: 582; 67.6% identity (88.5% similar) in 139 aa overlap (5-141:39-176) 10 20 30 pF1KB8 MASSDIQVKELEKRASGQAFELILSPRSKESVPE :..::.:.::::::.::.::. : : :: NP_056 KEKMKELSVLSLICSCFYTQPHPNTVYQYGDMEVKQLDKRASGQSFEVILKSPSDLS-PE 10 20 30 40 50 60 40 50 60 70 80 90 pF1KB8 FPL--SPPKKKDLSLEEIQKKLEAAEERRKSHEAEVLKQLAEKREHEKEVLQKAIEENNN :. ::::::: ::::.::.:::::::::..::.:::::::.::::.:::.::.::::: NP_056 SPMLSSPPKKKDTSLEELQKRLEAAEERRKTQEAQVLKQLAERREHEREVLHKALEENNN 70 80 90 100 110 120 100 110 120 130 140 pF1KB8 FSKMAEEKLTHKMEANKENREAQMAAKLERLREKDKHIEEVRKNKESKDPADETEAD ::..:::::..::: .:: :::..:: ::::::. : :::.:::... NP_056 FSRQAEEKLNYKMELSKEIREAHLAALRERLREKELHAAEVRRNKEQREEMSG 130 140 150 160 170 180 >>NP_001186143 (OMIM: 600621) stathmin-2 isoform 1 [Homo (187 aa) initn: 557 init1: 557 opt: 560 Z-score: 400.4 bits: 80.4 E(85289): 1.5e-15 Smith-Waterman score: 560; 71.0% identity (85.5% similar) in 138 aa overlap (5-140:39-176) 10 20 30 pF1KB8 MASSDIQVKELEKRASGQAFELILSPRSKESVPE :..::...::::::::::::.: : : NP_001 KEKMKELSMLSLICSCFYPEPRNINIYTYDDMEVKQINKRASGQAFELILKPPSPISEAP 10 20 30 40 50 60 40 50 60 70 80 90 pF1KB8 FPLSPPKKKDLSLEEIQKKLEAAEERRKSHEAEVLKQLAEKREHEKEVLQKAIEENNNFS :. ::::::::::::::::::::::::.::.::::::::::::.::::::.::::::: NP_001 RTLASPKKKDLSLEEIQKKLEAAEERRKSQEAQVLKQLAEKREHEREVLQKALEENNNFS 70 80 90 100 110 120 100 110 120 130 140 pF1KB8 KMAEEKLTHKMEANKENREAQMAAKLERLREKD-KHIE-EVRKNKESKDPADETEAD ::::::: ::: ::::::..:: .:::.:: : : :.... ::. NP_001 KMAEEKLILKMEQIKENREANLAAIIERLQEKLVKFISSELKESIESQFLELQREGEKQ 130 140 150 160 170 180 149 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 10:49:02 2016 done: Fri Nov 4 10:49:03 2016 Total Scan time: 5.580 Total Display time: -0.020 Function used was FASTA [36.3.4 Apr, 2011]