FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB8238, 297 aa 1>>>pF1KB8238 297 - 297 aa - 297 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 9.0971+/-0.000481; mu= -2.3917+/- 0.030 mean_var=202.3882+/-40.486, 0's: 0 Z-trim(115.0): 61 B-trim: 144 in 2/53 Lambda= 0.090153 statistics sampled from 25056 (25115) to 25056 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.64), E-opt: 0.2 (0.294), width: 16 Scan time: 6.020 The best scores are: opt bits E(85289) NP_004595 (OMIM: 186591) syntaxin-4 isoform 3 [Hom ( 297) 1858 254.3 2.2e-67 XP_005255578 (OMIM: 186591) PREDICTED: syntaxin-4 ( 293) 1564 216.0 7e-56 NP_001259025 (OMIM: 186591) syntaxin-4 isoform 2 [ ( 295) 1564 216.0 7e-56 NP_001259024 (OMIM: 186591) syntaxin-4 isoform 1 [ ( 219) 1354 188.6 9.2e-48 XP_011544227 (OMIM: 186591) PREDICTED: syntaxin-4 ( 154) 937 134.3 1.5e-31 NP_004594 (OMIM: 186590) syntaxin-1A isoform 1 [Ho ( 288) 785 114.7 2.2e-25 NP_001971 (OMIM: 132350) syntaxin-2 isoform 1 [Hom ( 287) 779 113.9 3.7e-25 XP_016874469 (OMIM: 132350) PREDICTED: syntaxin-2 ( 319) 779 113.9 4.1e-25 XP_016874472 (OMIM: 132350) PREDICTED: syntaxin-2 ( 260) 773 113.1 5.9e-25 NP_919337 (OMIM: 132350) syntaxin-2 isoform 2 [Hom ( 288) 773 113.1 6.4e-25 XP_016874467 (OMIM: 132350) PREDICTED: syntaxin-2 ( 320) 773 113.2 7e-25 XP_016874468 (OMIM: 132350) PREDICTED: syntaxin-2 ( 320) 773 113.2 7e-25 XP_016878382 (OMIM: 601485,616172) PREDICTED: synt ( 282) 764 112.0 1.4e-24 NP_443106 (OMIM: 601485,616172) syntaxin-1B [Homo ( 288) 764 112.0 1.4e-24 XP_005253614 (OMIM: 132350) PREDICTED: syntaxin-2 ( 277) 721 106.4 6.8e-23 XP_016874471 (OMIM: 132350) PREDICTED: syntaxin-2 ( 309) 721 106.4 7.4e-23 XP_016874470 (OMIM: 132350) PREDICTED: syntaxin-2 ( 317) 717 105.9 1.1e-22 XP_016873681 (OMIM: 600876) PREDICTED: syntaxin-3 ( 279) 707 104.5 2.4e-22 XP_016873682 (OMIM: 600876) PREDICTED: syntaxin-3 ( 279) 707 104.5 2.4e-22 XP_005274255 (OMIM: 600876) PREDICTED: syntaxin-3 ( 287) 707 104.5 2.5e-22 XP_016873678 (OMIM: 600876) PREDICTED: syntaxin-3 ( 281) 697 103.2 5.9e-22 XP_016873679 (OMIM: 600876) PREDICTED: syntaxin-3 ( 281) 697 103.2 5.9e-22 XP_016873677 (OMIM: 600876) PREDICTED: syntaxin-3 ( 281) 697 103.2 5.9e-22 XP_016873680 (OMIM: 600876) PREDICTED: syntaxin-3 ( 281) 697 103.2 5.9e-22 XP_005274252 (OMIM: 600876) PREDICTED: syntaxin-3 ( 289) 697 103.2 6.1e-22 NP_004168 (OMIM: 600876) syntaxin-3 isoform 1 [Hom ( 289) 697 103.2 6.1e-22 XP_016873683 (OMIM: 600876) PREDICTED: syntaxin-3 ( 269) 650 97.1 4e-20 NP_001171511 (OMIM: 600876) syntaxin-3 isoform 2 [ ( 277) 650 97.1 4.1e-20 XP_016874474 (OMIM: 132350) PREDICTED: syntaxin-2 ( 213) 606 91.3 1.7e-18 NP_001159375 (OMIM: 186590) syntaxin-1A isoform 2 ( 251) 607 91.5 1.8e-18 XP_016868056 (OMIM: 186590) PREDICTED: syntaxin-1A ( 329) 607 91.6 2.3e-18 XP_016874473 (OMIM: 132350) PREDICTED: syntaxin-2 ( 214) 600 90.6 3e-18 XP_011543523 (OMIM: 600876) PREDICTED: syntaxin-3 ( 192) 552 84.3 2.1e-16 XP_005274257 (OMIM: 600876) PREDICTED: syntaxin-3 ( 252) 552 84.4 2.6e-16 XP_016873684 (OMIM: 600876) PREDICTED: syntaxin-3 ( 244) 531 81.6 1.7e-15 XP_011534519 (OMIM: 603552,605014) PREDICTED: synt ( 287) 393 63.7 4.8e-10 XP_016866889 (OMIM: 603552,605014) PREDICTED: synt ( 287) 393 63.7 4.8e-10 XP_011534516 (OMIM: 603552,605014) PREDICTED: synt ( 287) 393 63.7 4.8e-10 XP_011534520 (OMIM: 603552,605014) PREDICTED: synt ( 287) 393 63.7 4.8e-10 NP_003755 (OMIM: 603552,605014) syntaxin-11 [Homo ( 287) 393 63.7 4.8e-10 XP_011534515 (OMIM: 603552,605014) PREDICTED: synt ( 313) 393 63.7 5.2e-10 XP_016873685 (OMIM: 600876) PREDICTED: syntaxin-3 ( 155) 386 62.6 5.5e-10 XP_016874477 (OMIM: 132350) PREDICTED: syntaxin-2 ( 167) 343 57.1 2.8e-08 XP_016874476 (OMIM: 132350) PREDICTED: syntaxin-2 ( 199) 343 57.1 3.2e-08 XP_016874475 (OMIM: 132350) PREDICTED: syntaxin-2 ( 200) 343 57.1 3.3e-08 NP_803173 (OMIM: 606892) syntaxin-12 [Homo sapiens ( 276) 294 50.8 3.5e-06 NP_003560 (OMIM: 603217) syntaxin-7 isoform a [Hom ( 261) 279 48.9 1.3e-05 NP_001313507 (OMIM: 603217) syntaxin-7 isoform a [ ( 261) 279 48.9 1.3e-05 NP_001313508 (OMIM: 603217) syntaxin-7 isoform a [ ( 261) 279 48.9 1.3e-05 NP_001313509 (OMIM: 603217) syntaxin-7 isoform b [ ( 239) 244 44.3 0.00028 >>NP_004595 (OMIM: 186591) syntaxin-4 isoform 3 [Homo sa (297 aa) initn: 1858 init1: 1858 opt: 1858 Z-score: 1330.8 bits: 254.3 E(85289): 2.2e-67 Smith-Waterman score: 1858; 100.0% identity (100.0% similar) in 297 aa overlap (1-297:1-297) 10 20 30 40 50 60 pF1KB8 MRDRTHELRQGDDSSDEEDKERVALVVHPGTARLGSPDEEFFHKVRTIRQTIVKLGNKVQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 MRDRTHELRQGDDSSDEEDKERVALVVHPGTARLGSPDEEFFHKVRTIRQTIVKLGNKVQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 ELEKQQVTILATPLPEESMKQELQNLRDEIKQLGREIRLQLKAIEPQKEEADENYNSVNT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 ELEKQQVTILATPLPEESMKQELQNLRDEIKQLGREIRLQLKAIEPQKEEADENYNSVNT 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 RMRKTQHGVLSQQFVELINKCNSMQSEYREKNVERIRRQLKITNAGMVSDEELEQMLDSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 RMRKTQHGVLSQQFVELINKCNSMQSEYREKNVERIRRQLKITNAGMVSDEELEQMLDSG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 QSEVFVSNILKDTQVTRQALNEISARHSEIQQLERSIRELHDIFTFLATEVEMQGEMINR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 QSEVFVSNILKDTQVTRQALNEISARHSEIQQLERSIRELHDIFTFLATEVEMQGEMINR 190 200 210 220 230 240 250 260 270 280 290 pF1KB8 IEKNILSSADYVERGQEHVKTALENQKKARKKKVLIAICVSITVVLLAVIIGVTVVG ::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 IEKNILSSADYVERGQEHVKTALENQKKARKKKVLIAICVSITVVLLAVIIGVTVVG 250 260 270 280 290 >>XP_005255578 (OMIM: 186591) PREDICTED: syntaxin-4 isof (293 aa) initn: 1560 init1: 1560 opt: 1564 Z-score: 1124.3 bits: 216.0 E(85289): 7e-56 Smith-Waterman score: 1564; 96.3% identity (97.0% similar) in 267 aa overlap (31-297:32-293) 10 20 30 40 50 60 pF1KB8 MRDRTHELRQGDDSSDEEDKERVALVVHPGTARLGSPDEEFFHKVRTIRQTIVKLGNKVQ :. :: : . :::::::::::::::: XP_005 TARTKRTRSGSRWWCTRARHGWGARTRSSSTSPLGHPPQ-----VRTIRQTIVKLGNKVQ 10 20 30 40 50 70 80 90 100 110 120 pF1KB8 ELEKQQVTILATPLPEESMKQELQNLRDEIKQLGREIRLQLKAIEPQKEEADENYNSVNT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ELEKQQVTILATPLPEESMKQELQNLRDEIKQLGREIRLQLKAIEPQKEEADENYNSVNT 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB8 RMRKTQHGVLSQQFVELINKCNSMQSEYREKNVERIRRQLKITNAGMVSDEELEQMLDSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RMRKTQHGVLSQQFVELINKCNSMQSEYREKNVERIRRQLKITNAGMVSDEELEQMLDSG 120 130 140 150 160 170 190 200 210 220 230 240 pF1KB8 QSEVFVSNILKDTQVTRQALNEISARHSEIQQLERSIRELHDIFTFLATEVEMQGEMINR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 QSEVFVSNILKDTQVTRQALNEISARHSEIQQLERSIRELHDIFTFLATEVEMQGEMINR 180 190 200 210 220 230 250 260 270 280 290 pF1KB8 IEKNILSSADYVERGQEHVKTALENQKKARKKKVLIAICVSITVVLLAVIIGVTVVG ::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 IEKNILSSADYVERGQEHVKTALENQKKARKKKVLIAICVSITVVLLAVIIGVTVVG 240 250 260 270 280 290 >>NP_001259025 (OMIM: 186591) syntaxin-4 isoform 2 [Homo (295 aa) initn: 1560 init1: 1560 opt: 1564 Z-score: 1124.2 bits: 216.0 E(85289): 7e-56 Smith-Waterman score: 1564; 96.3% identity (97.0% similar) in 267 aa overlap (31-297:34-295) 10 20 30 40 50 60 pF1KB8 MRDRTHELRQGDDSSDEEDKERVALVVHPGTARLGSPDEEFFHKVRTIRQTIVKLGNKVQ :. :: : . :::::::::::::::: NP_001 TARTKRTRSGSRWWCTRARHGWGARTRSSSTSPLGHPPQ-----VRTIRQTIVKLGNKVQ 10 20 30 40 50 70 80 90 100 110 120 pF1KB8 ELEKQQVTILATPLPEESMKQELQNLRDEIKQLGREIRLQLKAIEPQKEEADENYNSVNT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ELEKQQVTILATPLPEESMKQELQNLRDEIKQLGREIRLQLKAIEPQKEEADENYNSVNT 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB8 RMRKTQHGVLSQQFVELINKCNSMQSEYREKNVERIRRQLKITNAGMVSDEELEQMLDSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RMRKTQHGVLSQQFVELINKCNSMQSEYREKNVERIRRQLKITNAGMVSDEELEQMLDSG 120 130 140 150 160 170 190 200 210 220 230 240 pF1KB8 QSEVFVSNILKDTQVTRQALNEISARHSEIQQLERSIRELHDIFTFLATEVEMQGEMINR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QSEVFVSNILKDTQVTRQALNEISARHSEIQQLERSIRELHDIFTFLATEVEMQGEMINR 180 190 200 210 220 230 250 260 270 280 290 pF1KB8 IEKNILSSADYVERGQEHVKTALENQKKARKKKVLIAICVSITVVLLAVIIGVTVVG ::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IEKNILSSADYVERGQEHVKTALENQKKARKKKVLIAICVSITVVLLAVIIGVTVVG 240 250 260 270 280 290 >>NP_001259024 (OMIM: 186591) syntaxin-4 isoform 1 [Homo (219 aa) initn: 1354 init1: 1354 opt: 1354 Z-score: 978.5 bits: 188.6 E(85289): 9.2e-48 Smith-Waterman score: 1354; 100.0% identity (100.0% similar) in 219 aa overlap (79-297:1-219) 50 60 70 80 90 100 pF1KB8 RQTIVKLGNKVQELEKQQVTILATPLPEESMKQELQNLRDEIKQLGREIRLQLKAIEPQK :::::::::::::::::::::::::::::: NP_001 MKQELQNLRDEIKQLGREIRLQLKAIEPQK 10 20 30 110 120 130 140 150 160 pF1KB8 EEADENYNSVNTRMRKTQHGVLSQQFVELINKCNSMQSEYREKNVERIRRQLKITNAGMV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EEADENYNSVNTRMRKTQHGVLSQQFVELINKCNSMQSEYREKNVERIRRQLKITNAGMV 40 50 60 70 80 90 170 180 190 200 210 220 pF1KB8 SDEELEQMLDSGQSEVFVSNILKDTQVTRQALNEISARHSEIQQLERSIRELHDIFTFLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SDEELEQMLDSGQSEVFVSNILKDTQVTRQALNEISARHSEIQQLERSIRELHDIFTFLA 100 110 120 130 140 150 230 240 250 260 270 280 pF1KB8 TEVEMQGEMINRIEKNILSSADYVERGQEHVKTALENQKKARKKKVLIAICVSITVVLLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TEVEMQGEMINRIEKNILSSADYVERGQEHVKTALENQKKARKKKVLIAICVSITVVLLA 160 170 180 190 200 210 290 pF1KB8 VIIGVTVVG ::::::::: NP_001 VIIGVTVVG >>XP_011544227 (OMIM: 186591) PREDICTED: syntaxin-4 isof (154 aa) initn: 937 init1: 937 opt: 937 Z-score: 687.6 bits: 134.3 E(85289): 1.5e-31 Smith-Waterman score: 937; 100.0% identity (100.0% similar) in 154 aa overlap (144-297:1-154) 120 130 140 150 160 170 pF1KB8 NYNSVNTRMRKTQHGVLSQQFVELINKCNSMQSEYREKNVERIRRQLKITNAGMVSDEEL :::::::::::::::::::::::::::::: XP_011 MQSEYREKNVERIRRQLKITNAGMVSDEEL 10 20 30 180 190 200 210 220 230 pF1KB8 EQMLDSGQSEVFVSNILKDTQVTRQALNEISARHSEIQQLERSIRELHDIFTFLATEVEM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EQMLDSGQSEVFVSNILKDTQVTRQALNEISARHSEIQQLERSIRELHDIFTFLATEVEM 40 50 60 70 80 90 240 250 260 270 280 290 pF1KB8 QGEMINRIEKNILSSADYVERGQEHVKTALENQKKARKKKVLIAICVSITVVLLAVIIGV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QGEMINRIEKNILSSADYVERGQEHVKTALENQKKARKKKVLIAICVSITVVLLAVIIGV 100 110 120 130 140 150 pF1KB8 TVVG :::: XP_011 TVVG >>NP_004594 (OMIM: 186590) syntaxin-1A isoform 1 [Homo s (288 aa) initn: 769 init1: 507 opt: 785 Z-score: 576.8 bits: 114.7 E(85289): 2.2e-25 Smith-Waterman score: 785; 45.7% identity (76.8% similar) in 293 aa overlap (1-292:1-284) 10 20 30 40 50 60 pF1KB8 MRDRTHELRQGDDSSDEEDKERVALVVHPGTARLGSPDEEFFHKVRTIRQTIVKLGNKVQ :.:::.::: . ::.:..: ::..: :. .:::..:. :: : :....:. NP_004 MKDRTQELRTAKDSDDDDD---VAVTVD--RDRFM---DEFFEQVEEIRGFIDKIAENVE 10 20 30 40 50 70 80 90 100 110 pF1KB8 ELEKQQVTILATPLPEESMKQELQNLRDEIKQLGREIRLQLKAIEPQKE-EADENYNSVN :..... .:::.: :.:. :.::..: ..::. . ..: .::.:: . : : : .:.. NP_004 EVKRKHSAILASPNPDEKTKEELEELMSDIKKTANKVRSKLKSIEQSIEQEEGLNRSSAD 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB8 TRMRKTQHGVLSQQFVELINKCNSMQSEYREKNVERIRRQLKITNAGMVSDEELEQMLDS :.:::::..::..:::.... :. ::.:::. ::.:::.::. .: ::::.::.: NP_004 LRIRKTQHSTLSRKFVEVMSEYNATQSDYRERCKGRIQRQLEITGRTTTS-EELEDMLES 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB8 GQSEVFVSNILKDTQVTRQALNEISARHSEIQQLERSIRELHDIFTFLATEVEMQGEMIN :. .:.:.:. :.....:::.:: .::::: .:: :::::::.: .: :: :::::. NP_004 GNPAIFASGIIMDSSISKQALSEIETRHSEIIKLENSIRELHDMFMDMAMLVESQGEMID 180 190 200 210 220 230 240 250 260 270 280 290 pF1KB8 RIEKNILSSADYVERGQEHVKTALENQKKARKKKVLIAICVSITVVLLAVIIGVTVVG ::: :. ..:::::. .: :.. :.:::.::..: :: : ...: .: NP_004 RIEYNVEHAVDYVERAVSDTKKAVKYQSKARRKKIMIIICCVILGIVIASTVGGIFA 240 250 260 270 280 >>NP_001971 (OMIM: 132350) syntaxin-2 isoform 1 [Homo sa (287 aa) initn: 764 init1: 564 opt: 779 Z-score: 572.6 bits: 113.9 E(85289): 3.7e-25 Smith-Waterman score: 780; 44.1% identity (76.4% similar) in 297 aa overlap (1-295:1-286) 10 20 30 40 50 60 pF1KB8 MRDRTHELRQGDDSSDEEDKERVALVVHPGTARLGSPDEEFFHKVRTIRQTIVKLGNKVQ :::: .: ..: . :..: . ..:::.:. ::..: :. . :. NP_001 MRDRLPDLTA---CRKNDDGDTVVVVEKDHFM------DDFFHQVEEIRNSIDKITQYVE 10 20 30 40 50 70 80 90 100 110 pF1KB8 ELEKQQVTILATPLPEESMKQELQNLRDEIKQLGREIRLQLKAIEPQKEEADE--NYNSV :..:.. ::..: :: ..:.::..: :::. . .:: .::::: :. . :: : .:: NP_001 EVKKNHSIILSAPNPEGKIKEELEDLNKEIKKTANKIRAKLKAIE-QSFDQDESGNRTSV 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB8 NTRMRKTQHGVLSQQFVELINKCNSMQSEYREKNVERIRRQLKITNAGMVSDEELEQMLD . :.:.:::.:::..::: . . : :. .::.. ::.:::.::. ..:.:::.::. NP_001 DLRIRRTQHSVLSRKFVEAMAEYNEAQTLFRERSKGRIQRQLEITGR-TTTDDELEEMLE 120 130 140 150 160 180 190 200 210 220 230 pF1KB8 SGQSEVFVSNILKDTQVTRQALNEISARHSEIQQLERSIRELHDIFTFLATEVEMQGEMI ::. .:.:.:..:.:.:::::::: .::..:..:: ::::::..: .: :: ::::: NP_001 SGKPSIFTSDIISDSQITRQALNEIESRHKDIMKLETSIRELHEMFMDMAMFVETQGEMI 170 180 190 200 210 220 240 250 260 270 280 290 pF1KB8 NRIEKNILSSADYVERGQEHVKTALENQKKARKKKVLIAICVSITVVLLAVIIGVTVVG : ::.:.....::::...:..: :.. :.:::.: ..: ::: . .:.:..:...:. NP_001 NNIERNVMNATDYVEHAKEETKKAIKYQSKARRKLMFIIICVIVLLVILGIILATTLS 230 240 250 260 270 280 >>XP_016874469 (OMIM: 132350) PREDICTED: syntaxin-2 isof (319 aa) initn: 745 init1: 564 opt: 779 Z-score: 571.9 bits: 113.9 E(85289): 4.1e-25 Smith-Waterman score: 779; 47.5% identity (81.9% similar) in 259 aa overlap (39-295:62-318) 10 20 30 40 50 60 pF1KB8 RQGDDSSDEEDKERVALVVHPGTARLGSPDEEFFHKVRTIRQTIVKLGNKVQELEKQQVT ..:::.:. ::..: :. . :.:..:.. XP_016 SAWCLIQSTCQCRKNDDGDTVVVVEKDHFMDDFFHQVEEIRNSIDKITQYVEEVKKNHSI 40 50 60 70 80 90 70 80 90 100 110 120 pF1KB8 ILATPLPEESMKQELQNLRDEIKQLGREIRLQLKAIEPQKEEADE--NYNSVNTRMRKTQ ::..: :: ..:.::..: :::. . .:: .::::: :. . :: : .::. :.:.:: XP_016 ILSAPNPEGKIKEELEDLNKEIKKTANKIRAKLKAIE-QSFDQDESGNRTSVDLRIRRTQ 100 110 120 130 140 150 130 140 150 160 170 180 pF1KB8 HGVLSQQFVELINKCNSMQSEYREKNVERIRRQLKITNAGMVSDEELEQMLDSGQSEVFV :.:::..::: . . : :. .::.. ::.:::.::. ..:.:::.::.::. .:. XP_016 HSVLSRKFVEAMAEYNEAQTLFRERSKGRIQRQLEITGR-TTTDDELEEMLESGKPSIFT 160 170 180 190 200 190 200 210 220 230 240 pF1KB8 SNILKDTQVTRQALNEISARHSEIQQLERSIRELHDIFTFLATEVEMQGEMINRIEKNIL :.:..:.:.:::::::: .::..:..:: ::::::..: .: :: :::::: ::.:.. XP_016 SDIISDSQITRQALNEIESRHKDIMKLETSIRELHEMFMDMAMFVETQGEMINNIERNVM 210 220 230 240 250 260 250 260 270 280 290 pF1KB8 SSADYVERGQEHVKTALENQKKARKKKVLIAICVSITVVLLAVIIGVTVVG ...::::...:..: :.. :.:::.: ..: ::: . .:.:..:...:. XP_016 NATDYVEHAKEETKKAIKYQSKARRKLMFIIICVIVLLVILGIILATTLS 270 280 290 300 310 >>XP_016874472 (OMIM: 132350) PREDICTED: syntaxin-2 isof (260 aa) initn: 736 init1: 555 opt: 773 Z-score: 569.0 bits: 113.1 E(85289): 5.9e-25 Smith-Waterman score: 773; 48.1% identity (81.9% similar) in 260 aa overlap (39-295:2-258) 10 20 30 40 50 60 pF1KB8 RQGDDSSDEEDKERVALVVHPGTARLGSPDEEFFHKVRTIRQTIVKLGNKVQELEKQQVT ..:::.:. ::..: :. . :.:..:.. XP_016 MDDFFHQVEEIRNSIDKITQYVEEVKKNHSI 10 20 30 70 80 90 100 110 120 pF1KB8 ILATPLPEESMKQELQNLRDEIKQLGREIRLQLKAIEPQKEEADE--NYNSVNTRMRKTQ ::..: :: ..:.::..: :::. . .:: .::::: :. . :: : .::. :.:.:: XP_016 ILSAPNPEGKIKEELEDLNKEIKKTANKIRAKLKAIE-QSFDQDESGNRTSVDLRIRRTQ 40 50 60 70 80 90 130 140 150 160 170 180 pF1KB8 HGVLSQQFVELINKCNSMQSEYREKNVERIRRQLKITNAGMVSDEELEQMLDSGQSEVFV :.:::..::: . . : :. .::.. ::.:::.::. ..:.:::.::.::. .:. XP_016 HSVLSRKFVEAMAEYNEAQTLFRERSKGRIQRQLEITGR-TTTDDELEEMLESGKPSIFT 100 110 120 130 140 190 200 210 220 230 240 pF1KB8 SNILKDTQVTRQALNEISARHSEIQQLERSIRELHDIFTFLATEVEMQGEMINRIEKNIL :.:..:.:.:::::::: .::..:..:: ::::::..: .: :: :::::: ::.:.. XP_016 SDIISDSQITRQALNEIESRHKDIMKLETSIRELHEMFMDMAMFVETQGEMINNIERNVM 150 160 170 180 190 200 250 260 270 280 290 pF1KB8 SSADYVERGQEHVKTALENQKKARKKK-VLIAICVSITVVLLAVIIGVTVVG ...::::...:..: :.. :.:::.:: ..::. : . :...:.:::..: XP_016 NATDYVEHAKEETKKAIKYQSKARRKKWIIIAVSV-VLVAIIALIIGLSVGK 210 220 230 240 250 260 >>NP_919337 (OMIM: 132350) syntaxin-2 isoform 2 [Homo sa (288 aa) initn: 755 init1: 555 opt: 773 Z-score: 568.4 bits: 113.1 E(85289): 6.4e-25 Smith-Waterman score: 774; 44.6% identity (76.5% similar) in 298 aa overlap (1-295:1-286) 10 20 30 40 50 60 pF1KB8 MRDRTHELRQGDDSSDEEDKERVALVVHPGTARLGSPDEEFFHKVRTIRQTIVKLGNKVQ :::: .: ..: . :..: . ..:::.:. ::..: :. . :. NP_919 MRDRLPDLTA---CRKNDDGDTVVVVEKDHFM------DDFFHQVEEIRNSIDKITQYVE 10 20 30 40 50 70 80 90 100 110 pF1KB8 ELEKQQVTILATPLPEESMKQELQNLRDEIKQLGREIRLQLKAIEPQKEEADE--NYNSV :..:.. ::..: :: ..:.::..: :::. . .:: .::::: :. . :: : .:: NP_919 EVKKNHSIILSAPNPEGKIKEELEDLNKEIKKTANKIRAKLKAIE-QSFDQDESGNRTSV 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB8 NTRMRKTQHGVLSQQFVELINKCNSMQSEYREKNVERIRRQLKITNAGMVSDEELEQMLD . :.:.:::.:::..::: . . : :. .::.. ::.:::.::. ..:.:::.::. NP_919 DLRIRRTQHSVLSRKFVEAMAEYNEAQTLFRERSKGRIQRQLEITGR-TTTDDELEEMLE 120 130 140 150 160 180 190 200 210 220 230 pF1KB8 SGQSEVFVSNILKDTQVTRQALNEISARHSEIQQLERSIRELHDIFTFLATEVEMQGEMI ::. .:.:.:..:.:.:::::::: .::..:..:: ::::::..: .: :: ::::: NP_919 SGKPSIFTSDIISDSQITRQALNEIESRHKDIMKLETSIRELHEMFMDMAMFVETQGEMI 170 180 190 200 210 220 240 250 260 270 280 290 pF1KB8 NRIEKNILSSADYVERGQEHVKTALENQKKARKKK-VLIAICVSITVVLLAVIIGVTVVG : ::.:.....::::...:..: :.. :.:::.:: ..::. : . :...:.:::..: NP_919 NNIERNVMNATDYVEHAKEETKKAIKYQSKARRKKWIIIAVSV-VLVAIIALIIGLSVGK 230 240 250 260 270 280 297 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 10:51:28 2016 done: Fri Nov 4 10:51:29 2016 Total Scan time: 6.020 Total Display time: 0.000 Function used was FASTA [36.3.4 Apr, 2011]