FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB8242, 198 aa 1>>>pF1KB8242 198 - 198 aa - 198 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.1940+/-0.000802; mu= 11.4447+/- 0.049 mean_var=136.4322+/-27.290, 0's: 0 Z-trim(113.4): 43 B-trim: 118 in 1/51 Lambda= 0.109803 statistics sampled from 13992 (14034) to 13992 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.781), E-opt: 0.2 (0.431), width: 16 Scan time: 1.760 The best scores are: opt bits E(32554) CCDS5612.1 SRI gene_id:6717|Hs108|chr7 ( 198) 1386 229.9 8.1e-61 CCDS47638.1 SRI gene_id:6717|Hs108|chr7 ( 183) 1249 208.1 2.6e-54 CCDS59063.1 SRI gene_id:6717|Hs108|chr7 ( 180) 1194 199.4 1.1e-51 CCDS82527.1 GCA gene_id:25801|Hs108|chr2 ( 198) 811 138.8 2.1e-33 CCDS2218.1 GCA gene_id:25801|Hs108|chr2 ( 217) 811 138.8 2.3e-33 CCDS345.1 PEF1 gene_id:553115|Hs108|chr1 ( 284) 418 76.7 1.5e-14 CCDS3854.1 PDCD6 gene_id:10016|Hs108|chr5 ( 191) 414 75.9 1.8e-14 CCDS58940.1 PDCD6 gene_id:10016|Hs108|chr5 ( 189) 402 74.0 6.6e-14 CCDS45246.1 CAPN3 gene_id:825|Hs108|chr15 ( 309) 362 67.9 7.5e-12 CCDS12489.1 CAPNS1 gene_id:826|Hs108|chr19 ( 268) 359 67.3 9.4e-12 CCDS10085.1 CAPN3 gene_id:825|Hs108|chr15 ( 729) 362 68.3 1.3e-11 CCDS32207.1 CAPN3 gene_id:825|Hs108|chr15 ( 815) 362 68.3 1.4e-11 CCDS45245.1 CAPN3 gene_id:825|Hs108|chr15 ( 821) 362 68.3 1.5e-11 CCDS54010.1 CAPNS2 gene_id:84290|Hs108|chr16 ( 248) 339 64.1 8e-11 >>CCDS5612.1 SRI gene_id:6717|Hs108|chr7 (198 aa) initn: 1386 init1: 1386 opt: 1386 Z-score: 1205.3 bits: 229.9 E(32554): 8.1e-61 Smith-Waterman score: 1386; 100.0% identity (100.0% similar) in 198 aa overlap (1-198:1-198) 10 20 30 40 50 60 pF1KB8 MAYPGHPGAGGGYYPGGYGGAPGGPAFPGQTQDPLYGYFAAVAGQDGQIDADELQRCLTQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS56 MAYPGHPGAGGGYYPGGYGGAPGGPAFPGQTQDPLYGYFAAVAGQDGQIDADELQRCLTQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 SGIAGGYKPFNLETCRLMVSMLDRDMSGTMGFNEFKELWAVLNGWRQHFISFDTDRSGTV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS56 SGIAGGYKPFNLETCRLMVSMLDRDMSGTMGFNEFKELWAVLNGWRQHFISFDTDRSGTV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 DPQELQKALTTMGFRLSPQAVNSIAKRYSTNGKITFDDYIACCVKLRALTDSFRRRDTAQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS56 DPQELQKALTTMGFRLSPQAVNSIAKRYSTNGKITFDDYIACCVKLRALTDSFRRRDTAQ 130 140 150 160 170 180 190 pF1KB8 QGVVNFPYDDFIQCVMSV :::::::::::::::::: CCDS56 QGVVNFPYDDFIQCVMSV 190 >>CCDS47638.1 SRI gene_id:6717|Hs108|chr7 (183 aa) initn: 1249 init1: 1249 opt: 1249 Z-score: 1088.4 bits: 208.1 E(32554): 2.6e-54 Smith-Waterman score: 1249; 100.0% identity (100.0% similar) in 181 aa overlap (18-198:3-183) 10 20 30 40 50 60 pF1KB8 MAYPGHPGAGGGYYPGGYGGAPGGPAFPGQTQDPLYGYFAAVAGQDGQIDADELQRCLTQ ::::::::::::::::::::::::::::::::::::::::::: CCDS47 MQYGGAPGGPAFPGQTQDPLYGYFAAVAGQDGQIDADELQRCLTQ 10 20 30 40 70 80 90 100 110 120 pF1KB8 SGIAGGYKPFNLETCRLMVSMLDRDMSGTMGFNEFKELWAVLNGWRQHFISFDTDRSGTV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 SGIAGGYKPFNLETCRLMVSMLDRDMSGTMGFNEFKELWAVLNGWRQHFISFDTDRSGTV 50 60 70 80 90 100 130 140 150 160 170 180 pF1KB8 DPQELQKALTTMGFRLSPQAVNSIAKRYSTNGKITFDDYIACCVKLRALTDSFRRRDTAQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 DPQELQKALTTMGFRLSPQAVNSIAKRYSTNGKITFDDYIACCVKLRALTDSFRRRDTAQ 110 120 130 140 150 160 190 pF1KB8 QGVVNFPYDDFIQCVMSV :::::::::::::::::: CCDS47 QGVVNFPYDDFIQCVMSV 170 180 >>CCDS59063.1 SRI gene_id:6717|Hs108|chr7 (180 aa) initn: 1194 init1: 1194 opt: 1194 Z-score: 1041.4 bits: 199.4 E(32554): 1.1e-51 Smith-Waterman score: 1194; 100.0% identity (100.0% similar) in 173 aa overlap (18-190:3-175) 10 20 30 40 50 60 pF1KB8 MAYPGHPGAGGGYYPGGYGGAPGGPAFPGQTQDPLYGYFAAVAGQDGQIDADELQRCLTQ ::::::::::::::::::::::::::::::::::::::::::: CCDS59 MQYGGAPGGPAFPGQTQDPLYGYFAAVAGQDGQIDADELQRCLTQ 10 20 30 40 70 80 90 100 110 120 pF1KB8 SGIAGGYKPFNLETCRLMVSMLDRDMSGTMGFNEFKELWAVLNGWRQHFISFDTDRSGTV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS59 SGIAGGYKPFNLETCRLMVSMLDRDMSGTMGFNEFKELWAVLNGWRQHFISFDTDRSGTV 50 60 70 80 90 100 130 140 150 160 170 180 pF1KB8 DPQELQKALTTMGFRLSPQAVNSIAKRYSTNGKITFDDYIACCVKLRALTDSFRRRDTAQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS59 DPQELQKALTTMGFRLSPQAVNSIAKRYSTNGKITFDDYIACCVKLRALTDSFRRRDTAQ 110 120 130 140 150 160 190 pF1KB8 QGVVNFPYDDFIQCVMSV :::::::::: CCDS59 QGVVNFPYDDVSLRN 170 180 >>CCDS82527.1 GCA gene_id:25801|Hs108|chr2 (198 aa) initn: 817 init1: 782 opt: 811 Z-score: 713.0 bits: 138.8 E(32554): 2.1e-33 Smith-Waterman score: 811; 59.4% identity (82.3% similar) in 192 aa overlap (7-198:8-198) 10 20 30 40 50 pF1KB8 MAYPGHPGAGGGYYPGGYGGAPGGPAFPGQTQDPLYGYFAAVAGQDGQIDADELQRCLT : .: . ::.: :. ... : .: ::.:::::::..::.::::::: CCDS82 MQMGQPVPETGPAILLDGYSG-PAYSDTYSSAGDSVYTYFSAVAGQDGEVDAEELQRCLT 10 20 30 40 50 60 70 80 90 100 110 pF1KB8 QSGIAGGYKPFNLETCRLMVSMLDRDMSGTMGFNEFKELWAVLNGWRQHFISFDTDRSGT :::: : :.::.:::::.:..::::: .: :::: ::::::.::.:...:.. : : ::: CCDS82 QSGINGTYSPFSLETCRIMIAMLDRDHTGKMGFNAFKELWAALNAWKENFMTVDQDGSGT 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB8 VDPQELQKALTTMGFRLSPQAVNSIAKRYSTNGKITFDDYIACCVKLRALTDSFRRRDTA :. .::..:. ::.:::::....:.:::: ::.: ::::.::::::::::: ::.:: CCDS82 VEHHELRQAIGLMGYRLSPQTLTTIVKRYSKNGRIFFDDYVACCVKLRALTDFFRKRDHL 120 130 140 150 160 170 180 190 pF1KB8 QQGVVNFPYDDFIQCVMSV ::: .:: ::::.: .:.. CCDS82 QQGSANFIYDDFLQGTMAI 180 190 >>CCDS2218.1 GCA gene_id:25801|Hs108|chr2 (217 aa) initn: 860 init1: 782 opt: 811 Z-score: 712.6 bits: 138.8 E(32554): 2.3e-33 Smith-Waterman score: 833; 56.2% identity (77.4% similar) in 217 aa overlap (1-198:1-217) 10 20 30 40 pF1KB8 MAYPGHPGAGGGY---YPGGYGGAP-------------GGPAFP---GQTQDPLYGYFAA :::::. :. :.. :: : : .:::. ... : .: ::.: CCDS22 MAYPGYGGGFGNFSIQVPGMQMGQPVPETGPAILLDGYSGPAYSDTYSSAGDSVYTYFSA 10 20 30 40 50 60 50 60 70 80 90 100 pF1KB8 VAGQDGQIDADELQRCLTQSGIAGGYKPFNLETCRLMVSMLDRDMSGTMGFNEFKELWAV ::::::..::.::::::::::: : :.::.:::::.:..::::: .: :::: ::::::. CCDS22 VAGQDGEVDAEELQRCLTQSGINGTYSPFSLETCRIMIAMLDRDHTGKMGFNAFKELWAA 70 80 90 100 110 120 110 120 130 140 150 160 pF1KB8 LNGWRQHFISFDTDRSGTVDPQELQKALTTMGFRLSPQAVNSIAKRYSTNGKITFDDYIA ::.:...:.. : : ::::. .::..:. ::.:::::....:.:::: ::.: ::::.: CCDS22 LNAWKENFMTVDQDGSGTVEHHELRQAIGLMGYRLSPQTLTTIVKRYSKNGRIFFDDYVA 130 140 150 160 170 180 170 180 190 pF1KB8 CCVKLRALTDSFRRRDTAQQGVVNFPYDDFIQCVMSV :::::::::: ::.:: ::: .:: ::::.: .:.. CCDS22 CCVKLRALTDFFRKRDHLQQGSANFIYDDFLQGTMAI 190 200 210 >>CCDS345.1 PEF1 gene_id:553115|Hs108|chr1 (284 aa) initn: 422 init1: 252 opt: 418 Z-score: 374.7 bits: 76.7 E(32554): 1.5e-14 Smith-Waterman score: 432; 35.9% identity (62.7% similar) in 217 aa overlap (5-197:65-281) 10 20 pF1KB8 MAYPGHPGAG--GGYYPGG-YGGA-PGGP-AFP- :::. : . ::: :::: :::: . : CCDS34 QYGSGLPPGGGYGGPAPGGPYGPPAGGGPYGHPNPGMFPSGTPGGPYGGAAPGGPYGQPP 40 50 60 70 80 90 30 40 50 60 70 pF1KB8 ----GQTQDPLYGYFAAVAGQDGQ-------IDADEL----QRCLTQSGIAGGYKPFNLE : : ::: .: . : . .:.:. .. : :. . ... :: : CCDS34 PSSYGAQQPGLYGQGGAPPNVDPEAYSWFQSVDSDHSGYISMKELKQALVNCNWSSFNDE 100 110 120 130 140 150 80 90 100 110 120 130 pF1KB8 TCRLMVSMLDRDMSGTMGFNEFKELWAVLNGWRQHFISFDTDRSGTVDPQELQKALTTMG :: .:..:.:. :: . :. :: .. :.. : ..: ::::... :::.::. :: CCDS34 TCLMMINMFDKTKSGRIDVYGFSALWKFIQQWKNLFQQYDRDRSGSISYTELQQALSQMG 160 170 180 190 200 210 140 150 160 170 180 190 pF1KB8 FRLSPQAVNSIAKRY---STNGKITFDDYIACCVKLRALTDSFRRRDTAQQGVVNFPYDD . :::: .. ...:: :.: . .: .: :..:..::..::..::: :: . . ..: CCDS34 YNLSPQFTQLLVSRYCPRSANPAMQLDRFIQVCTQLQVLTEAFREKDTAVQGNIRLSFED 220 230 240 250 260 270 pF1KB8 FIQCVMSV :. . : CCDS34 FVTMTASRML 280 >>CCDS3854.1 PDCD6 gene_id:10016|Hs108|chr5 (191 aa) initn: 446 init1: 212 opt: 414 Z-score: 373.3 bits: 75.9 E(32554): 1.8e-14 Smith-Waterman score: 419; 36.5% identity (66.0% similar) in 200 aa overlap (2-198:3-190) 10 20 30 40 50 pF1KB8 MAYPGHPGAGGGYYPGGYGGAPGGPAFPGQTQDPLYGYFAAV-AGQDGQIDADELQRCL :: .:: :.: :: .:: :.: :. :.. : : ..: :. :::. : CCDS38 MAAYSYRPGPGAG--PGPAAGA----ALPDQSF--LWNVFQRVDKDRSGVISDTELQQAL 10 20 30 40 50 60 70 80 90 100 110 pF1KB8 TQSGIAGGYKPFNLETCRLMVSMLDRDMSGTMGFNEFKELWAVLNGWRQHFISFDTDRSG .. : . ::: : : ..::.::. .. ..:.:: .: .. :.. : ..: : :: CCDS38 SN----GTWTPFNPVTVRSIISMFDRENKAGVNFSEFTGVWKYITDWQNVFRTYDRDNSG 60 70 80 90 100 120 130 140 150 160 170 pF1KB8 TVDPQELQKALTTMGFRLSPQAVNSIAKRYSTNGK--ITFDDYIACCVKLRALTDSFRRR .: .::..::. .:.::: : . . .... .:. :.:::.: :. :. ::: ::: CCDS38 MIDKNELKQALSGFGYRLSDQFHDILIRKFDRQGRGQIAFDDFIQGCIVLQRLTDIFRRY 110 120 130 140 150 160 180 190 pF1KB8 DTAQQGVVNFPYDDFIQCVMSV :: :.: .. :..... :.:. CCDS38 DTDQDGWIQVSYEQYLSMVFSIV 170 180 190 >>CCDS58940.1 PDCD6 gene_id:10016|Hs108|chr5 (189 aa) initn: 440 init1: 298 opt: 402 Z-score: 363.1 bits: 74.0 E(32554): 6.6e-14 Smith-Waterman score: 407; 36.5% identity (65.5% similar) in 200 aa overlap (2-198:3-188) 10 20 30 40 50 pF1KB8 MAYPGHPGAGGGYYPGGYGGAPGGPAFPGQTQDPLYGYFAAV-AGQDGQIDADELQRCL :: .:: :.: :: .:: :.: :. :.. : : ..: :. :::. : CCDS58 MAAYSYRPGPGAG--PGPAAGA----ALPDQSF--LWNVFQRVDKDRSGVISDTELQQAL 10 20 30 40 50 60 70 80 90 100 110 pF1KB8 TQSGIAGGYKPFNLETCRLMVSMLDRDMSGTMGFNEFKELWAVLNGWRQHFISFDTDRSG .. : . ::: : : ..::.::. .. ..:.:: .: .. :.. : ..: : :: CCDS58 SN----GTWTPFNPVTVRSIISMFDRENKAGVNFSEFTGVWKYITDWQNVFRTYDRDNSG 60 70 80 90 100 120 130 140 150 160 170 pF1KB8 TVDPQELQKALTTMGFRLSPQAVNSIAKRYSTNGK--ITFDDYIACCVKLRALTDSFRRR .: .::..::. :.::: : . . .... .:. :.:::.: :. :. ::: ::: CCDS58 MIDKNELKQALS--GYRLSDQFHDILIRKFDRQGRGQIAFDDFIQGCIVLQRLTDIFRRY 110 120 130 140 150 160 180 190 pF1KB8 DTAQQGVVNFPYDDFIQCVMSV :: :.: .. :..... :.:. CCDS58 DTDQDGWIQVSYEQYLSMVFSIV 170 180 >>CCDS45246.1 CAPN3 gene_id:825|Hs108|chr15 (309 aa) initn: 316 init1: 250 opt: 362 Z-score: 326.3 bits: 67.9 E(32554): 7.5e-12 Smith-Waterman score: 362; 31.5% identity (68.0% similar) in 181 aa overlap (22-196:129-307) 10 20 30 40 50 pF1KB8 MAYPGHPGAGGGYYPGGYGGAPGGPAFPGQTQDPLYGYFAAVAGQDGQIDA ::. .. :. . . : .::.: .: : CCDS45 SNKELGVDQESEEGKGKTSPDKQKQSPQPQPGSSDQESEEQQQFRNIFKQIAGDDMEICA 100 110 120 130 140 150 60 70 80 90 100 pF1KB8 DELQRCLTQSGIAGGYKP-----FNLETCRLMVSMLDRDMSGTMGFNEFKELWAVLNGWR :::.. : . ... .: :.::.:: :....: : :: ....::..:: ...:. CCDS45 DELKKVL--NTVVNKHKDLKTHGFTLESCRSMIALMDTDGSGKLNLQEFHHLWNKIKAWQ 160 170 180 190 200 210 110 120 130 140 150 160 pF1KB8 QHFISFDTDRSGTVDPQELQKALTTMGFRLSPQAVNSIAKRYSTNG-KITFDDYIACCVK . : .:::.:::.. :...:.. ::.:. : . :. ::. . .: ::..: : :. CCDS45 KIFKHYDTDQSGTINSYEMRNAVNDAGFHLNNQLYDIITMRYADKHMNIDFDSFICCFVR 220 230 240 250 260 270 170 180 190 pF1KB8 LRALTDSFRRRDTAQQGVVNFPYDDFIQCVMSV :... .:. : .:.... ...: .: CCDS45 LEGMFRAFHAFDKDGDGIIKLNVLEWLQLTMYA 280 290 300 >>CCDS12489.1 CAPNS1 gene_id:826|Hs108|chr19 (268 aa) initn: 315 init1: 254 opt: 359 Z-score: 324.5 bits: 67.3 E(32554): 9.4e-12 Smith-Waterman score: 359; 36.4% identity (65.4% similar) in 162 aa overlap (39-196:105-266) 10 20 30 40 50 60 pF1KB8 AGGGYYPGGYGGAPGGPAFPGQTQDPLYGYFAAVAGQDGQIDADELQRCLTQSGIAG-GY :: .::.: ...: ::. :.. CCDS12 QYNPEPPPPRTHYSNIEANESEEVRQFRRLFAQLAGDDMEVSATELMNILNKVVTRHPDL 80 90 100 110 120 130 70 80 90 100 110 120 pF1KB8 KP--FNLETCRLMVSMLDRDMSGTMGFNEFKELWAVLNGWRQHFISFDTDRSGTVDPQEL : :...::: ::...: : .: .::.::: :: .. :. . .::::::::. .:: CCDS12 KTDGFGIDTCRSMVAVMDSDTTGKLGFEEFKYLWNNIKRWQAIYKQFDTDRSGTICSSEL 140 150 160 170 180 190 130 140 150 160 170 180 pF1KB8 QKALTTMGFRLSPQAVNSIAKRYST-NGKITFDDYIACCVKLRALTDSFRRRDTAQQGVV :. . ::.:. . : : .::: .:.. ::..:.: :.: :. .:. : : . CCDS12 PGAFEAAGFHLNEHLYNMIIRRYSDESGNMDFDNFISCLVRLDAMFRAFKSLDKDGTGQI 200 210 220 230 240 250 190 pF1KB8 NFPYDDFIQCVMSV . ....: .: CCDS12 QVNIQEWLQLTMYS 260 198 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 10:54:55 2016 done: Fri Nov 4 10:54:55 2016 Total Scan time: 1.760 Total Display time: -0.010 Function used was FASTA [36.3.4 Apr, 2011]