FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB8245, 180 aa 1>>>pF1KB8245 180 - 180 aa - 180 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.3419+/-0.00106; mu= 12.6660+/- 0.065 mean_var=80.8293+/-18.183, 0's: 0 Z-trim(104.5): 168 B-trim: 543 in 2/48 Lambda= 0.142656 statistics sampled from 7751 (7956) to 7751 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.622), E-opt: 0.2 (0.244), width: 16 Scan time: 1.440 The best scores are: opt bits E(32554) CCDS2884.1 ARF4 gene_id:378|Hs108|chr3 ( 180) 1173 250.9 3e-67 CCDS34745.1 ARF5 gene_id:381|Hs108|chr7 ( 180) 1096 235.1 1.8e-62 CCDS1565.1 ARF1 gene_id:375|Hs108|chr1 ( 181) 975 210.2 5.6e-55 CCDS8774.1 ARF3 gene_id:377|Hs108|chr12 ( 181) 960 207.1 4.8e-54 CCDS9695.1 ARF6 gene_id:382|Hs108|chr14 ( 175) 797 173.6 5.8e-44 CCDS44958.1 ARL1 gene_id:400|Hs108|chr12 ( 181) 699 153.4 7.1e-38 CCDS3987.1 TRIM23 gene_id:373|Hs108|chr5 ( 574) 664 146.6 2.5e-35 CCDS43322.1 TRIM23 gene_id:373|Hs108|chr5 ( 569) 580 129.3 4e-30 CCDS2195.1 ARL5A gene_id:26225|Hs108|chr2 ( 179) 569 126.6 7.9e-30 CCDS7131.1 ARL5B gene_id:221079|Hs108|chr10 ( 179) 564 125.6 1.6e-29 CCDS8088.1 ARL2 gene_id:402|Hs108|chr11 ( 184) 547 122.1 1.9e-28 CCDS3986.1 TRIM23 gene_id:373|Hs108|chr5 ( 546) 552 123.5 2.1e-28 CCDS3192.1 ARL14 gene_id:80117|Hs108|chr3 ( 192) 528 118.2 2.9e-27 CCDS5359.1 ARL4A gene_id:10124|Hs108|chr7 ( 200) 515 115.6 1.9e-26 CCDS7538.1 ARL3 gene_id:403|Hs108|chr10 ( 182) 505 113.5 7.4e-26 CCDS2512.1 ARL4C gene_id:10123|Hs108|chr2 ( 192) 503 113.1 1e-25 CCDS63169.1 ARL4C gene_id:10123|Hs108|chr2 ( 201) 503 113.1 1.1e-25 CCDS73510.1 ARL1 gene_id:400|Hs108|chr12 ( 135) 482 108.6 1.6e-24 CCDS45664.1 ARL5C gene_id:390790|Hs108|chr17 ( 179) 460 104.2 4.5e-23 CCDS46425.1 ARL5A gene_id:26225|Hs108|chr2 ( 142) 452 102.5 1.2e-22 CCDS11463.1 ARL4D gene_id:379|Hs108|chr17 ( 201) 452 102.6 1.5e-22 CCDS2928.1 ARL6 gene_id:84100|Hs108|chr3 ( 186) 441 100.3 7e-22 CCDS9419.1 ARL11 gene_id:115761|Hs108|chr13 ( 196) 427 97.4 5.3e-21 CCDS74086.1 ARL17A gene_id:51326|Hs108|chr17 ( 88) 399 91.4 1.6e-19 CCDS74087.1 ARL17A gene_id:51326|Hs108|chr17 ( 141) 399 91.6 2.3e-19 CCDS45718.1 ARL17A gene_id:51326|Hs108|chr17 ( 177) 399 91.6 2.7e-19 CCDS58557.1 ARL17B gene_id:100506084|Hs108|chr17 ( 177) 399 91.6 2.7e-19 CCDS45717.1 ARL17A gene_id:51326|Hs108|chr17 ( 125) 393 90.3 4.8e-19 CCDS54137.1 ARL17B gene_id:100506084|Hs108|chr17 ( 125) 393 90.3 4.8e-19 CCDS82146.1 ARL17A gene_id:51326|Hs108|chr17 ( 95) 391 89.8 5.2e-19 CCDS82144.1 ARL17B gene_id:100506084|Hs108|chr17 ( 95) 391 89.8 5.2e-19 CCDS2566.1 ARL8B gene_id:55207|Hs108|chr3 ( 186) 372 86.1 1.3e-17 CCDS55770.1 ARL2 gene_id:402|Hs108|chr11 ( 157) 362 84.0 4.8e-17 CCDS1421.1 ARL8A gene_id:127829|Hs108|chr1 ( 186) 360 83.6 7.3e-17 CCDS13533.1 ARFRP1 gene_id:10139|Hs108|chr20 ( 201) 348 81.2 4.3e-16 CCDS46630.1 ARFRP1 gene_id:10139|Hs108|chr20 ( 173) 305 72.3 1.8e-13 CCDS2925.1 ARL13B gene_id:200894|Hs108|chr3 ( 428) 304 72.4 4e-13 CCDS54850.1 ARL15 gene_id:54622|Hs108|chr5 ( 204) 299 71.1 4.7e-13 CCDS4400.1 ARL10 gene_id:285598|Hs108|chr5 ( 244) 297 70.8 7.1e-13 CCDS4177.1 SAR1B gene_id:51128|Hs108|chr5 ( 198) 284 68.0 3.9e-12 CCDS68172.1 ARFRP1 gene_id:10139|Hs108|chr20 ( 154) 280 67.1 5.7e-12 CCDS73004.1 ARL8A gene_id:127829|Hs108|chr1 ( 147) 275 66.1 1.1e-11 CCDS7298.1 SAR1A gene_id:56681|Hs108|chr10 ( 198) 268 64.7 3.8e-11 >>CCDS2884.1 ARF4 gene_id:378|Hs108|chr3 (180 aa) initn: 1173 init1: 1173 opt: 1173 Z-score: 1320.8 bits: 250.9 E(32554): 3e-67 Smith-Waterman score: 1173; 100.0% identity (100.0% similar) in 180 aa overlap (1-180:1-180) 10 20 30 40 50 60 pF1KB8 MGLTISSLFSRLFGKKQMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS28 MGLTISSLFSRLFGKKQMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKN 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 ICFTVWDVGGQDRIRPLWKHYFQNTQGLIFVVDSNDRERIQEVADELQKMLLVDELRDAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS28 ICFTVWDVGGQDRIRPLWKHYFQNTQGLIFVVDSNDRERIQEVADELQKMLLVDELRDAV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 LLLFANKQDLPNAMAISEMTDKLGLQSLRNRTWYVQATCATQGTGLYEGLDWLSNELSKR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS28 LLLFANKQDLPNAMAISEMTDKLGLQSLRNRTWYVQATCATQGTGLYEGLDWLSNELSKR 130 140 150 160 170 180 >>CCDS34745.1 ARF5 gene_id:381|Hs108|chr7 (180 aa) initn: 1096 init1: 1096 opt: 1096 Z-score: 1235.1 bits: 235.1 E(32554): 1.8e-62 Smith-Waterman score: 1096; 90.0% identity (97.2% similar) in 180 aa overlap (1-180:1-180) 10 20 30 40 50 60 pF1KB8 MGLTISSLFSRLFGKKQMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKN ::::.:.::::.:::::::::::::::::::::::::::::::::::::::::::::::: CCDS34 MGLTVSALFSRIFGKKQMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKN 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 ICFTVWDVGGQDRIRPLWKHYFQNTQGLIFVVDSNDRERIQEVADELQKMLLVDELRDAV ::::::::::::.:::::.::::::::::::::::::::.:: :::::::: ::::::: CCDS34 ICFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERVQESADELQKMLQEDELRDAV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 LLLFANKQDLPNAMAISEMTDKLGLQSLRNRTWYVQATCATQGTGLYEGLDWLSNELSKR ::.::::::.:::: .::.::::::: ::.:::::::::::::::::.::::::.::::: CCDS34 LLVFANKQDMPNAMPVSELTDKLGLQHLRSRTWYVQATCATQGTGLYDGLDWLSHELSKR 130 140 150 160 170 180 >>CCDS1565.1 ARF1 gene_id:375|Hs108|chr1 (181 aa) initn: 975 init1: 975 opt: 975 Z-score: 1100.5 bits: 210.2 E(32554): 5.6e-55 Smith-Waterman score: 975; 81.9% identity (94.4% similar) in 177 aa overlap (1-177:1-177) 10 20 30 40 50 60 pF1KB8 MGLTISSLFSRLFGKKQMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKN :: ...::. :::::.::::::::::::::::::::::::::::::::::::::::::: CCDS15 MGNIFANLFKGLFGKKEMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKN 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 ICFTVWDVGGQDRIRPLWKHYFQNTQGLIFVVDSNDRERIQEVADELQKMLLVDELRDAV : ::::::::::.:::::.::::::::::::::::::::..:. .::..:: ::::::: CCDS15 ISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERVNEAREELMRMLAEDELRDAV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 LLLFANKQDLPNAMAISEMTDKLGLQSLRNRTWYVQATCATQGTGLYEGLDWLSNELSKR ::.::::::::::: .:.::::::.:::.:.::.::::::.: :::::::::::.: CCDS15 LLVFANKQDLPNAMNAAEITDKLGLHSLRHRNWYIQATCATSGDGLYEGLDWLSNQLRNQ 130 140 150 160 170 180 CCDS15 K >>CCDS8774.1 ARF3 gene_id:377|Hs108|chr12 (181 aa) initn: 960 init1: 960 opt: 960 Z-score: 1083.8 bits: 207.1 E(32554): 4.8e-54 Smith-Waterman score: 960; 78.9% identity (94.4% similar) in 180 aa overlap (1-180:1-180) 10 20 30 40 50 60 pF1KB8 MGLTISSLFSRLFGKKQMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKN :: ...:.. :.:::.::::::::::::::::::::::::::::::::::::::::::: CCDS87 MGNIFGNLLKSLIGKKEMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKN 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 ICFTVWDVGGQDRIRPLWKHYFQNTQGLIFVVDSNDRERIQEVADELQKMLLVDELRDAV : ::::::::::.:::::.::::::::::::::::::::..:. .::..:: ::::::: CCDS87 ISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERVNEAREELMRMLAEDELRDAV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 LLLFANKQDLPNAMAISEMTDKLGLQSLRNRTWYVQATCATQGTGLYEGLDWLSNELSKR ::.::::::::::: .:.::::::.:::.:.::.::::::.: :::::::::.:.:... CCDS87 LLVFANKQDLPNAMNAAEITDKLGLHSLRHRNWYIQATCATSGDGLYEGLDWLANQLKNK 130 140 150 160 170 180 CCDS87 K >>CCDS9695.1 ARF6 gene_id:382|Hs108|chr14 (175 aa) initn: 810 init1: 783 opt: 797 Z-score: 902.7 bits: 173.6 E(32554): 5.8e-44 Smith-Waterman score: 797; 65.5% identity (88.9% similar) in 171 aa overlap (5-175:1-171) 10 20 30 40 50 60 pF1KB8 MGLTISSLFSRLFGKKQMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKN .....:..::.:.:::::.:::::::::::::::::. ::::::.::::::: ::: CCDS96 MGKVLSKIFGNKEMRILMLGLDAAGKTTILYKLKLGQSVTTIPTVGFNVETVTYKN 10 20 30 40 50 70 80 90 100 110 120 pF1KB8 ICFTVWDVGGQDRIRPLWKHYFQNTQGLIFVVDSNDRERIQEVADELQKMLLVDELRDAV . :.::::::::.:::::.::. .::::::::: ::.::.:. .::.... :.:::. CCDS96 VKFNVWDVGGQDKIRPLWRHYYTGTQGLIFVVDCADRDRIDEARQELHRIINDREMRDAI 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB8 LLLFANKQDLPNAMAISEMTDKLGLQSLRNRTWYVQATCATQGTGLYEGLDWLSNELSKR .:.::::::::.:: :. .:::: .:.:.:::: .:::.: :::::: ::.. CCDS96 ILIFANKQDLPDAMKPHEIQEKLGLTRIRDRNWYVQPSCATSGDGLYEGLTWLTSNYKS 120 130 140 150 160 170 >>CCDS44958.1 ARL1 gene_id:400|Hs108|chr12 (181 aa) initn: 699 init1: 699 opt: 699 Z-score: 793.5 bits: 153.4 E(32554): 7.1e-38 Smith-Waterman score: 699; 58.3% identity (82.2% similar) in 180 aa overlap (1-180:1-180) 10 20 30 40 50 60 pF1KB8 MGLTISSLFSRLFGKKQMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKN :: .::.:: ::: ..::::..:::.::::::::.:..::.:::::::::::::: ::: CCDS44 MGGFFSSIFSSLFGTREMRILILGLDGAGKTTILYRLQVGEVVTTIPTIGFNVETVTYKN 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 ICFTVWDVGGQDRIRPLWKHYFQNTQGLIFVVDSNDRERIQEVADELQKMLLVDELRDAV . : :::.::: ::: :. :..::...:.:::: ::.:: .:: :: .::: :. CCDS44 LKFQVWDLGGQTSIRPYWRCYYSNTDAVIYVVDSCDRDRIGISKSELVAMLEEEELRKAI 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 LLLFANKQDLPNAMAISEMTDKLGLQSLRNRTWYVQATCATQGTGLYEGLDWLSNELSKR :..::::::. .::. :::...::: .:..: : . : ::.:::: :...:: . :..: CCDS44 LVVFANKQDMEQAMTSSEMANSLGLPALKDRKWQIFKTSATKGTGLDEAMEWLVETLKSR 130 140 150 160 170 180 CCDS44 Q >>CCDS3987.1 TRIM23 gene_id:373|Hs108|chr5 (574 aa) initn: 676 init1: 532 opt: 664 Z-score: 747.7 bits: 146.6 E(32554): 2.5e-35 Smith-Waterman score: 664; 59.1% identity (84.8% similar) in 164 aa overlap (15-177:402-565) 10 20 30 40 pF1KB8 MGLTISSLFSRLFGKKQMRILMVGLDAAGKTTILYKLKLGEIVT : ..:.. .:::.:::::::.::: :.. CCDS39 QQFTEVADHIQLDASIPVTFTKDNRVHIGPKMEIRVVTLGLDGAGKTTILFKLKQDEFMQ 380 390 400 410 420 430 50 60 70 80 90 100 pF1KB8 TIPTIGFNVETVEYKNICFTVWDVGGQDRIRPLWKHYFQNTQGLIFVVDSNDRERIQEVA :::::::::::::::. ::.:::::. ..:::::::. :::...:::::. :.::.:. CCDS39 PIPTIGFNVETVEYKNLKFTIWDVGGKHKLRPLWKHYYLNTQAVVFVVDSSHRDRISEAH 440 450 460 470 480 490 110 120 130 140 150 160 pF1KB8 DELQKMLLVDELRDAVLLLFANKQDLPNAMAISEMTDKLGLQSLR-NRTWYVQATCATQG .:: :.: :::::.::.::::::. .:... :.:. :.:..: .:.::.:. : .: CCDS39 SELAKLLTEKELRDALLLIFANKQDVAGALSVEEITELLSLHKLCCGRSWYIQGCDARSG 500 510 520 530 540 550 170 180 pF1KB8 TGLYEGLDWLSNELSKR :::::::::: .: CCDS39 MGLYEGLDWLSRQLVAAGVLDVA 560 570 >>CCDS43322.1 TRIM23 gene_id:373|Hs108|chr5 (569 aa) initn: 591 init1: 532 opt: 580 Z-score: 654.3 bits: 129.3 E(32554): 4e-30 Smith-Waterman score: 580; 58.2% identity (85.6% similar) in 146 aa overlap (15-159:402-546) 10 20 30 40 pF1KB8 MGLTISSLFSRLFGKKQMRILMVGLDAAGKTTILYKLKLGEIVT : ..:.. .:::.:::::::.::: :.. CCDS43 QQFTEVADHIQLDASIPVTFTKDNRVHIGPKMEIRVVTLGLDGAGKTTILFKLKQDEFMQ 380 390 400 410 420 430 50 60 70 80 90 100 pF1KB8 TIPTIGFNVETVEYKNICFTVWDVGGQDRIRPLWKHYFQNTQGLIFVVDSNDRERIQEVA :::::::::::::::. ::.:::::. ..:::::::. :::...:::::. :.::.:. CCDS43 PIPTIGFNVETVEYKNLKFTIWDVGGKHKLRPLWKHYYLNTQAVVFVVDSSHRDRISEAH 440 450 460 470 480 490 110 120 130 140 150 160 pF1KB8 DELQKMLLVDELRDAVLLLFANKQDLPNAMAISEMTDKLGLQSLR-NRTWYVQATCATQG .:: :.: :::::.::.::::::. .:... :.:. :.:..: .:.::.:. : CCDS43 SELAKLLTEKELRDALLLIFANKQDVAGALSVEEITELLSLHKLCCGRSWYIQG-CDARS 500 510 520 530 540 550 170 180 pF1KB8 TGLYEGLDWLSNELSKR CCDS43 VFQIICDQYTGKEVVTEKG 560 >>CCDS2195.1 ARL5A gene_id:26225|Hs108|chr2 (179 aa) initn: 561 init1: 561 opt: 569 Z-score: 649.0 bits: 126.6 E(32554): 7.9e-30 Smith-Waterman score: 569; 46.1% identity (77.2% similar) in 180 aa overlap (1-180:1-179) 10 20 30 40 50 60 pF1KB8 MGLTISSLFSRLFGKKQMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKN ::. .. .. :::.... ....:::: ::::::::.....:.: : :::: ::: . .: CCDS21 MGILFTRIW-RLFNHQEHKVIIVGLDNAGKTTILYQFSMNEVVHTSPTIGSNVEEIVINN 10 20 30 40 50 70 80 90 100 110 120 pF1KB8 ICFTVWDVGGQDRIRPLWKHYFQNTQGLIFVVDSNDRERIQEVADELQKMLLVDELRDAV : .::.:::. .: :. :. ::. .: ::::.:::::. . .:: ::: ..:: : CCDS21 TRFLMWDIGGQESLRSSWNTYYTNTEFVIVVVDSTDRERISVTREELYKMLAHEDLRKAG 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB8 LLLFANKQDLPNAMAISEMTDKLGLQSLRNRTWYVQATCATQGTGLYEGLDWLSNELSKR ::.::::::. . :...:... : : :.... :..:: :: : :: .::.:. ..:. : CCDS21 LLIFANKQDVKECMTVAEISQFLKLTSIKDHQWHIQACCALTGEGLCQGLEWMMSRLKIR 120 130 140 150 160 170 >>CCDS7131.1 ARL5B gene_id:221079|Hs108|chr10 (179 aa) initn: 576 init1: 545 opt: 564 Z-score: 643.4 bits: 125.6 E(32554): 1.6e-29 Smith-Waterman score: 564; 45.0% identity (77.2% similar) in 180 aa overlap (1-180:1-179) 10 20 30 40 50 60 pF1KB8 MGLTISSLFSRLFGKKQMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKN ::: ...:.: :: ... ....:::: ::::::::.. ..:.: : :::: ::: . :: CCDS71 MGLIFAKLWS-LFCNQEHKVIIVGLDNAGKTTILYQFLMNEVVHTSPTIGSNVEEIVVKN 10 20 30 40 50 70 80 90 100 110 120 pF1KB8 ICFTVWDVGGQDRIRPLWKHYFQNTQGLIFVVDSNDRERIQEVADELQKMLLVDELRDAV : .::.:::. .: :. :..::. .:.:::: ::::. . .:: .:: ..:: :. CCDS71 THFLMWDIGGQESLRSSWNTYYSNTEFIILVVDSIDRERLAITKEELYRMLAHEDLRKAA 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB8 LLLFANKQDLPNAMAISEMTDKLGLQSLRNRTWYVQATCATQGTGLYEGLDWLSNELSKR .:.::::::. . :. .:.. : :.:.... :..:. :: : :: .::.:...... : CCDS71 VLIFANKQDMKGCMTAAEISKYLTLSSIKDHPWHIQSCCALTGEGLCQGLEWMTSRIGVR 120 130 140 150 160 170 180 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 10:56:58 2016 done: Fri Nov 4 10:56:58 2016 Total Scan time: 1.440 Total Display time: -0.020 Function used was FASTA [36.3.4 Apr, 2011]