FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB8245, 180 aa 1>>>pF1KB8245 180 - 180 aa - 180 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 4.5983+/-0.000478; mu= 17.3386+/- 0.030 mean_var=92.0526+/-20.230, 0's: 0 Z-trim(111.3): 264 B-trim: 1349 in 2/53 Lambda= 0.133677 statistics sampled from 19468 (19871) to 19468 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.604), E-opt: 0.2 (0.233), width: 16 Scan time: 3.900 The best scores are: opt bits E(85289) NP_001651 (OMIM: 601177) ADP-ribosylation factor 4 ( 180) 1173 236.2 2.2e-62 NP_001653 (OMIM: 103188) ADP-ribosylation factor 5 ( 180) 1096 221.3 6.5e-58 NP_001019399 (OMIM: 103180) ADP-ribosylation facto ( 181) 975 198.0 6.9e-51 NP_001019398 (OMIM: 103180) ADP-ribosylation facto ( 181) 975 198.0 6.9e-51 NP_001019397 (OMIM: 103180) ADP-ribosylation facto ( 181) 975 198.0 6.9e-51 NP_001649 (OMIM: 103180) ADP-ribosylation factor 1 ( 181) 975 198.0 6.9e-51 XP_005268913 (OMIM: 103190) PREDICTED: ADP-ribosyl ( 181) 960 195.1 5.1e-50 NP_001650 (OMIM: 103190) ADP-ribosylation factor 3 ( 181) 960 195.1 5.1e-50 NP_001654 (OMIM: 600464) ADP-ribosylation factor 6 ( 175) 797 163.7 1.5e-40 XP_016856722 (OMIM: 103180) PREDICTED: ADP-ribosyl ( 212) 702 145.4 5.4e-35 NP_001168 (OMIM: 603425) ADP-ribosylation factor-l ( 181) 699 144.8 7.3e-35 XP_006719454 (OMIM: 103190) PREDICTED: ADP-ribosyl ( 137) 688 142.5 2.7e-34 XP_005248554 (OMIM: 601747) PREDICTED: E3 ubiquiti ( 398) 664 138.5 1.3e-32 NP_001647 (OMIM: 601747) E3 ubiquitin-protein liga ( 574) 664 138.7 1.6e-32 XP_016864933 (OMIM: 601747) PREDICTED: E3 ubiquiti ( 569) 580 122.5 1.2e-27 NP_150230 (OMIM: 601747) E3 ubiquitin-protein liga ( 569) 580 122.5 1.2e-27 NP_036229 (OMIM: 608960) ADP-ribosylation factor-l ( 179) 569 119.7 2.5e-27 NP_848930 (OMIM: 608909) ADP-ribosylation factor-l ( 179) 564 118.7 5e-27 NP_001658 (OMIM: 601175) ADP-ribosylation factor-l ( 184) 547 115.5 4.9e-26 NP_150231 (OMIM: 601747) E3 ubiquitin-protein liga ( 546) 552 117.0 4.9e-26 NP_079323 (OMIM: 614439) ADP-ribosylation factor-l ( 192) 528 111.8 6.4e-25 NP_001032241 (OMIM: 604786) ADP-ribosylation facto ( 200) 515 109.3 3.7e-24 NP_005729 (OMIM: 604786) ADP-ribosylation factor-l ( 200) 515 109.3 3.7e-24 NP_997625 (OMIM: 604786) ADP-ribosylation factor-l ( 200) 515 109.3 3.7e-24 NP_001182325 (OMIM: 604786) ADP-ribosylation facto ( 200) 515 109.3 3.7e-24 XP_016871749 (OMIM: 604695) PREDICTED: ADP-ribosyl ( 182) 505 107.4 1.3e-23 NP_004302 (OMIM: 604695) ADP-ribosylation factor-l ( 182) 505 107.4 1.3e-23 NP_005728 (OMIM: 604787) ADP-ribosylation factor-l ( 192) 503 107.0 1.8e-23 NP_001269360 (OMIM: 604787) ADP-ribosylation facto ( 201) 503 107.0 1.9e-23 NP_001287997 (OMIM: 603425) ADP-ribosylation facto ( 135) 482 102.8 2.4e-22 NP_001032251 (OMIM: 608960) ADP-ribosylation facto ( 142) 452 97.0 1.4e-20 NP_817114 (OMIM: 608960) ADP-ribosylation factor-l ( 142) 452 97.0 1.4e-20 NP_001652 (OMIM: 600732) ADP-ribosylation factor-l ( 201) 452 97.2 1.7e-20 XP_011523084 (OMIM: 600732) PREDICTED: ADP-ribosyl ( 201) 452 97.2 1.7e-20 XP_005252458 (OMIM: 608909) PREDICTED: ADP-ribosyl ( 142) 449 96.4 2e-20 NP_001265222 (OMIM: 209900,268000,600151,608845,61 ( 186) 441 95.0 7e-20 XP_016862800 (OMIM: 209900,268000,600151,608845,61 ( 186) 441 95.0 7e-20 NP_816931 (OMIM: 209900,268000,600151,608845,61357 ( 186) 441 95.0 7e-20 NP_115522 (OMIM: 209900,268000,600151,608845,61357 ( 186) 441 95.0 7e-20 NP_001310442 (OMIM: 209900,268000,600151,608845,61 ( 193) 436 94.1 1.4e-19 XP_005266310 (OMIM: 609351) PREDICTED: ADP-ribosyl ( 196) 427 92.4 4.7e-19 NP_612459 (OMIM: 609351) ADP-ribosylation factor-l ( 196) 427 92.4 4.7e-19 NP_060654 (OMIM: 616596) ADP-ribosylation factor-l ( 186) 372 81.7 7.1e-16 XP_016862801 (OMIM: 209900,268000,600151,608845,61 ( 159) 367 80.7 1.3e-15 NP_001310443 (OMIM: 209900,268000,600151,608845,61 ( 159) 367 80.7 1.3e-15 NP_001186674 (OMIM: 601175) ADP-ribosylation facto ( 157) 362 79.7 2.4e-15 NP_620150 (OMIM: 616597) ADP-ribosylation factor-l ( 186) 360 79.4 3.5e-15 XP_011526784 (OMIM: 604699) PREDICTED: ADP-ribosyl ( 201) 348 77.1 1.8e-14 XP_011526785 (OMIM: 604699) PREDICTED: ADP-ribosyl ( 201) 348 77.1 1.8e-14 XP_016883065 (OMIM: 604699) PREDICTED: ADP-ribosyl ( 201) 348 77.1 1.8e-14 >>NP_001651 (OMIM: 601177) ADP-ribosylation factor 4 [Ho (180 aa) initn: 1173 init1: 1173 opt: 1173 Z-score: 1241.0 bits: 236.2 E(85289): 2.2e-62 Smith-Waterman score: 1173; 100.0% identity (100.0% similar) in 180 aa overlap (1-180:1-180) 10 20 30 40 50 60 pF1KB8 MGLTISSLFSRLFGKKQMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MGLTISSLFSRLFGKKQMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKN 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 ICFTVWDVGGQDRIRPLWKHYFQNTQGLIFVVDSNDRERIQEVADELQKMLLVDELRDAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ICFTVWDVGGQDRIRPLWKHYFQNTQGLIFVVDSNDRERIQEVADELQKMLLVDELRDAV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 LLLFANKQDLPNAMAISEMTDKLGLQSLRNRTWYVQATCATQGTGLYEGLDWLSNELSKR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LLLFANKQDLPNAMAISEMTDKLGLQSLRNRTWYVQATCATQGTGLYEGLDWLSNELSKR 130 140 150 160 170 180 >>NP_001653 (OMIM: 103188) ADP-ribosylation factor 5 [Ho (180 aa) initn: 1096 init1: 1096 opt: 1096 Z-score: 1160.7 bits: 221.3 E(85289): 6.5e-58 Smith-Waterman score: 1096; 90.0% identity (97.2% similar) in 180 aa overlap (1-180:1-180) 10 20 30 40 50 60 pF1KB8 MGLTISSLFSRLFGKKQMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKN ::::.:.::::.:::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MGLTVSALFSRIFGKKQMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKN 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 ICFTVWDVGGQDRIRPLWKHYFQNTQGLIFVVDSNDRERIQEVADELQKMLLVDELRDAV ::::::::::::.:::::.::::::::::::::::::::.:: :::::::: ::::::: NP_001 ICFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERVQESADELQKMLQEDELRDAV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 LLLFANKQDLPNAMAISEMTDKLGLQSLRNRTWYVQATCATQGTGLYEGLDWLSNELSKR ::.::::::.:::: .::.::::::: ::.:::::::::::::::::.::::::.::::: NP_001 LLVFANKQDMPNAMPVSELTDKLGLQHLRSRTWYVQATCATQGTGLYDGLDWLSHELSKR 130 140 150 160 170 180 >>NP_001019399 (OMIM: 103180) ADP-ribosylation factor 1 (181 aa) initn: 975 init1: 975 opt: 975 Z-score: 1034.6 bits: 198.0 E(85289): 6.9e-51 Smith-Waterman score: 975; 81.9% identity (94.4% similar) in 177 aa overlap (1-177:1-177) 10 20 30 40 50 60 pF1KB8 MGLTISSLFSRLFGKKQMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKN :: ...::. :::::.::::::::::::::::::::::::::::::::::::::::::: NP_001 MGNIFANLFKGLFGKKEMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKN 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 ICFTVWDVGGQDRIRPLWKHYFQNTQGLIFVVDSNDRERIQEVADELQKMLLVDELRDAV : ::::::::::.:::::.::::::::::::::::::::..:. .::..:: ::::::: NP_001 ISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERVNEAREELMRMLAEDELRDAV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 LLLFANKQDLPNAMAISEMTDKLGLQSLRNRTWYVQATCATQGTGLYEGLDWLSNELSKR ::.::::::::::: .:.::::::.:::.:.::.::::::.: :::::::::::.: NP_001 LLVFANKQDLPNAMNAAEITDKLGLHSLRHRNWYIQATCATSGDGLYEGLDWLSNQLRNQ 130 140 150 160 170 180 NP_001 K >>NP_001019398 (OMIM: 103180) ADP-ribosylation factor 1 (181 aa) initn: 975 init1: 975 opt: 975 Z-score: 1034.6 bits: 198.0 E(85289): 6.9e-51 Smith-Waterman score: 975; 81.9% identity (94.4% similar) in 177 aa overlap (1-177:1-177) 10 20 30 40 50 60 pF1KB8 MGLTISSLFSRLFGKKQMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKN :: ...::. :::::.::::::::::::::::::::::::::::::::::::::::::: NP_001 MGNIFANLFKGLFGKKEMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKN 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 ICFTVWDVGGQDRIRPLWKHYFQNTQGLIFVVDSNDRERIQEVADELQKMLLVDELRDAV : ::::::::::.:::::.::::::::::::::::::::..:. .::..:: ::::::: NP_001 ISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERVNEAREELMRMLAEDELRDAV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 LLLFANKQDLPNAMAISEMTDKLGLQSLRNRTWYVQATCATQGTGLYEGLDWLSNELSKR ::.::::::::::: .:.::::::.:::.:.::.::::::.: :::::::::::.: NP_001 LLVFANKQDLPNAMNAAEITDKLGLHSLRHRNWYIQATCATSGDGLYEGLDWLSNQLRNQ 130 140 150 160 170 180 NP_001 K >>NP_001019397 (OMIM: 103180) ADP-ribosylation factor 1 (181 aa) initn: 975 init1: 975 opt: 975 Z-score: 1034.6 bits: 198.0 E(85289): 6.9e-51 Smith-Waterman score: 975; 81.9% identity (94.4% similar) in 177 aa overlap (1-177:1-177) 10 20 30 40 50 60 pF1KB8 MGLTISSLFSRLFGKKQMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKN :: ...::. :::::.::::::::::::::::::::::::::::::::::::::::::: NP_001 MGNIFANLFKGLFGKKEMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKN 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 ICFTVWDVGGQDRIRPLWKHYFQNTQGLIFVVDSNDRERIQEVADELQKMLLVDELRDAV : ::::::::::.:::::.::::::::::::::::::::..:. .::..:: ::::::: NP_001 ISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERVNEAREELMRMLAEDELRDAV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 LLLFANKQDLPNAMAISEMTDKLGLQSLRNRTWYVQATCATQGTGLYEGLDWLSNELSKR ::.::::::::::: .:.::::::.:::.:.::.::::::.: :::::::::::.: NP_001 LLVFANKQDLPNAMNAAEITDKLGLHSLRHRNWYIQATCATSGDGLYEGLDWLSNQLRNQ 130 140 150 160 170 180 NP_001 K >>NP_001649 (OMIM: 103180) ADP-ribosylation factor 1 [Ho (181 aa) initn: 975 init1: 975 opt: 975 Z-score: 1034.6 bits: 198.0 E(85289): 6.9e-51 Smith-Waterman score: 975; 81.9% identity (94.4% similar) in 177 aa overlap (1-177:1-177) 10 20 30 40 50 60 pF1KB8 MGLTISSLFSRLFGKKQMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKN :: ...::. :::::.::::::::::::::::::::::::::::::::::::::::::: NP_001 MGNIFANLFKGLFGKKEMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKN 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 ICFTVWDVGGQDRIRPLWKHYFQNTQGLIFVVDSNDRERIQEVADELQKMLLVDELRDAV : ::::::::::.:::::.::::::::::::::::::::..:. .::..:: ::::::: NP_001 ISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERVNEAREELMRMLAEDELRDAV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 LLLFANKQDLPNAMAISEMTDKLGLQSLRNRTWYVQATCATQGTGLYEGLDWLSNELSKR ::.::::::::::: .:.::::::.:::.:.::.::::::.: :::::::::::.: NP_001 LLVFANKQDLPNAMNAAEITDKLGLHSLRHRNWYIQATCATSGDGLYEGLDWLSNQLRNQ 130 140 150 160 170 180 NP_001 K >>XP_005268913 (OMIM: 103190) PREDICTED: ADP-ribosylatio (181 aa) initn: 960 init1: 960 opt: 960 Z-score: 1019.0 bits: 195.1 E(85289): 5.1e-50 Smith-Waterman score: 960; 78.9% identity (94.4% similar) in 180 aa overlap (1-180:1-180) 10 20 30 40 50 60 pF1KB8 MGLTISSLFSRLFGKKQMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKN :: ...:.. :.:::.::::::::::::::::::::::::::::::::::::::::::: XP_005 MGNIFGNLLKSLIGKKEMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKN 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 ICFTVWDVGGQDRIRPLWKHYFQNTQGLIFVVDSNDRERIQEVADELQKMLLVDELRDAV : ::::::::::.:::::.::::::::::::::::::::..:. .::..:: ::::::: XP_005 ISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERVNEAREELMRMLAEDELRDAV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 LLLFANKQDLPNAMAISEMTDKLGLQSLRNRTWYVQATCATQGTGLYEGLDWLSNELSKR ::.::::::::::: .:.::::::.:::.:.::.::::::.: :::::::::.:.:... XP_005 LLVFANKQDLPNAMNAAEITDKLGLHSLRHRNWYIQATCATSGDGLYEGLDWLANQLKNK 130 140 150 160 170 180 XP_005 K >>NP_001650 (OMIM: 103190) ADP-ribosylation factor 3 [Ho (181 aa) initn: 960 init1: 960 opt: 960 Z-score: 1019.0 bits: 195.1 E(85289): 5.1e-50 Smith-Waterman score: 960; 78.9% identity (94.4% similar) in 180 aa overlap (1-180:1-180) 10 20 30 40 50 60 pF1KB8 MGLTISSLFSRLFGKKQMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKN :: ...:.. :.:::.::::::::::::::::::::::::::::::::::::::::::: NP_001 MGNIFGNLLKSLIGKKEMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKN 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 ICFTVWDVGGQDRIRPLWKHYFQNTQGLIFVVDSNDRERIQEVADELQKMLLVDELRDAV : ::::::::::.:::::.::::::::::::::::::::..:. .::..:: ::::::: NP_001 ISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERVNEAREELMRMLAEDELRDAV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 LLLFANKQDLPNAMAISEMTDKLGLQSLRNRTWYVQATCATQGTGLYEGLDWLSNELSKR ::.::::::::::: .:.::::::.:::.:.::.::::::.: :::::::::.:.:... NP_001 LLVFANKQDLPNAMNAAEITDKLGLHSLRHRNWYIQATCATSGDGLYEGLDWLANQLKNK 130 140 150 160 170 180 NP_001 K >>NP_001654 (OMIM: 600464) ADP-ribosylation factor 6 [Ho (175 aa) initn: 810 init1: 783 opt: 797 Z-score: 849.2 bits: 163.7 E(85289): 1.5e-40 Smith-Waterman score: 797; 65.5% identity (88.9% similar) in 171 aa overlap (5-175:1-171) 10 20 30 40 50 60 pF1KB8 MGLTISSLFSRLFGKKQMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKN .....:..::.:.:::::.:::::::::::::::::. ::::::.::::::: ::: NP_001 MGKVLSKIFGNKEMRILMLGLDAAGKTTILYKLKLGQSVTTIPTVGFNVETVTYKN 10 20 30 40 50 70 80 90 100 110 120 pF1KB8 ICFTVWDVGGQDRIRPLWKHYFQNTQGLIFVVDSNDRERIQEVADELQKMLLVDELRDAV . :.::::::::.:::::.::. .::::::::: ::.::.:. .::.... :.:::. NP_001 VKFNVWDVGGQDKIRPLWRHYYTGTQGLIFVVDCADRDRIDEARQELHRIINDREMRDAI 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB8 LLLFANKQDLPNAMAISEMTDKLGLQSLRNRTWYVQATCATQGTGLYEGLDWLSNELSKR .:.::::::::.:: :. .:::: .:.:.:::: .:::.: :::::: ::.. NP_001 ILIFANKQDLPDAMKPHEIQEKLGLTRIRDRNWYVQPSCATSGDGLYEGLTWLTSNYKS 120 130 140 150 160 170 >>XP_016856722 (OMIM: 103180) PREDICTED: ADP-ribosylatio (212 aa) initn: 702 init1: 702 opt: 702 Z-score: 749.3 bits: 145.4 E(85289): 5.4e-35 Smith-Waterman score: 702; 83.6% identity (94.5% similar) in 128 aa overlap (1-128:1-128) 10 20 30 40 50 60 pF1KB8 MGLTISSLFSRLFGKKQMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKN :: ...::. :::::.::::::::::::::::::::::::::::::::::::::::::: XP_016 MGNIFANLFKGLFGKKEMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKN 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 ICFTVWDVGGQDRIRPLWKHYFQNTQGLIFVVDSNDRERIQEVADELQKMLLVDELRDAV : ::::::::::.:::::.::::::::::::::::::::..:. .::..:: ::::::: XP_016 ISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERVNEAREELMRMLAEDELRDAV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 LLLFANKQDLPNAMAISEMTDKLGLQSLRNRTWYVQATCATQGTGLYEGLDWLSNELSKR ::.::::: XP_016 LLVFANKQVGARASLGNVRSQCGFRLVVGVTGGWWGPFLCPVDSPSHQPFLPPGPPQRHE 130 140 150 160 170 180 180 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 10:56:58 2016 done: Fri Nov 4 10:56:59 2016 Total Scan time: 3.900 Total Display time: 0.000 Function used was FASTA [36.3.4 Apr, 2011]