FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB8246, 245 aa 1>>>pF1KB8246 245 - 245 aa - 245 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.1186+/-0.000383; mu= 14.9994+/- 0.024 mean_var=57.8324+/-11.611, 0's: 0 Z-trim(110.9): 8 B-trim: 0 in 0/54 Lambda= 0.168651 statistics sampled from 19381 (19388) to 19381 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.595), E-opt: 0.2 (0.227), width: 16 Scan time: 5.290 The best scores are: opt bits E(85289) NP_002203 (OMIM: 602912) eukaryotic translation in ( 245) 1593 395.9 3.3e-110 NP_001254739 (OMIM: 602912) eukaryotic translation ( 245) 1593 395.9 3.3e-110 NP_852133 (OMIM: 602912) eukaryotic translation in ( 245) 1593 395.9 3.3e-110 NP_852131 (OMIM: 602912) eukaryotic translation in ( 226) 767 194.9 9.8e-50 >>NP_002203 (OMIM: 602912) eukaryotic translation initia (245 aa) initn: 1593 init1: 1593 opt: 1593 Z-score: 2099.5 bits: 395.9 E(85289): 3.3e-110 Smith-Waterman score: 1593; 100.0% identity (100.0% similar) in 245 aa overlap (1-245:1-245) 10 20 30 40 50 60 pF1KB8 MAVRASFENNCEIGCFAKLTNTYCLVAIGGSENFYSVFEGELSDTIPVVHASIAGCRIIG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 MAVRASFENNCEIGCFAKLTNTYCLVAIGGSENFYSVFEGELSDTIPVVHASIAGCRIIG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 RMCVGNRHGLLVPNNTTDQELQHIRNSLPDTVQIRRVEERLSALGNVTTCNDYVALVHPD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 RMCVGNRHGLLVPNNTTDQELQHIRNSLPDTVQIRRVEERLSALGNVTTCNDYVALVHPD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 LDRETEEILADVLKVEVFRQTVADQVLVGSYCVFSNQGGLVHPKTSIEDQDELSSLLQVP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 LDRETEEILADVLKVEVFRQTVADQVLVGSYCVFSNQGGLVHPKTSIEDQDELSSLLQVP 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 LVAGTVNRGSEVIAAGMVVNDWCAFCGLDTTSTELSVVESVFKLNEAQPSTIATSMRDSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 LVAGTVNRGSEVIAAGMVVNDWCAFCGLDTTSTELSVVESVFKLNEAQPSTIATSMRDSL 190 200 210 220 230 240 pF1KB8 IDSLT ::::: NP_002 IDSLT >>NP_001254739 (OMIM: 602912) eukaryotic translation ini (245 aa) initn: 1593 init1: 1593 opt: 1593 Z-score: 2099.5 bits: 395.9 E(85289): 3.3e-110 Smith-Waterman score: 1593; 100.0% identity (100.0% similar) in 245 aa overlap (1-245:1-245) 10 20 30 40 50 60 pF1KB8 MAVRASFENNCEIGCFAKLTNTYCLVAIGGSENFYSVFEGELSDTIPVVHASIAGCRIIG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MAVRASFENNCEIGCFAKLTNTYCLVAIGGSENFYSVFEGELSDTIPVVHASIAGCRIIG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 RMCVGNRHGLLVPNNTTDQELQHIRNSLPDTVQIRRVEERLSALGNVTTCNDYVALVHPD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RMCVGNRHGLLVPNNTTDQELQHIRNSLPDTVQIRRVEERLSALGNVTTCNDYVALVHPD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 LDRETEEILADVLKVEVFRQTVADQVLVGSYCVFSNQGGLVHPKTSIEDQDELSSLLQVP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LDRETEEILADVLKVEVFRQTVADQVLVGSYCVFSNQGGLVHPKTSIEDQDELSSLLQVP 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 LVAGTVNRGSEVIAAGMVVNDWCAFCGLDTTSTELSVVESVFKLNEAQPSTIATSMRDSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LVAGTVNRGSEVIAAGMVVNDWCAFCGLDTTSTELSVVESVFKLNEAQPSTIATSMRDSL 190 200 210 220 230 240 pF1KB8 IDSLT ::::: NP_001 IDSLT >>NP_852133 (OMIM: 602912) eukaryotic translation initia (245 aa) initn: 1593 init1: 1593 opt: 1593 Z-score: 2099.5 bits: 395.9 E(85289): 3.3e-110 Smith-Waterman score: 1593; 100.0% identity (100.0% similar) in 245 aa overlap (1-245:1-245) 10 20 30 40 50 60 pF1KB8 MAVRASFENNCEIGCFAKLTNTYCLVAIGGSENFYSVFEGELSDTIPVVHASIAGCRIIG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_852 MAVRASFENNCEIGCFAKLTNTYCLVAIGGSENFYSVFEGELSDTIPVVHASIAGCRIIG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 RMCVGNRHGLLVPNNTTDQELQHIRNSLPDTVQIRRVEERLSALGNVTTCNDYVALVHPD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_852 RMCVGNRHGLLVPNNTTDQELQHIRNSLPDTVQIRRVEERLSALGNVTTCNDYVALVHPD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 LDRETEEILADVLKVEVFRQTVADQVLVGSYCVFSNQGGLVHPKTSIEDQDELSSLLQVP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_852 LDRETEEILADVLKVEVFRQTVADQVLVGSYCVFSNQGGLVHPKTSIEDQDELSSLLQVP 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 LVAGTVNRGSEVIAAGMVVNDWCAFCGLDTTSTELSVVESVFKLNEAQPSTIATSMRDSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_852 LVAGTVNRGSEVIAAGMVVNDWCAFCGLDTTSTELSVVESVFKLNEAQPSTIATSMRDSL 190 200 210 220 230 240 pF1KB8 IDSLT ::::: NP_852 IDSLT >>NP_852131 (OMIM: 602912) eukaryotic translation initia (226 aa) initn: 992 init1: 767 opt: 767 Z-score: 1013.9 bits: 194.9 E(85289): 9.8e-50 Smith-Waterman score: 939; 68.3% identity (73.9% similar) in 249 aa overlap (1-245:1-226) 10 20 30 40 50 60 pF1KB8 MAVRASFENNCEIGCFAKLTNTYCLVAIGGSENFYSVFEGELSDTIPVVHASIAGCRIIG ::::::::::::::::::::::::::::::::::: .. : : NP_852 MAVRASFENNCEIGCFAKLTNTYCLVAIGGSENFYRC-------------GGSPGAYGGG 10 20 30 40 70 80 90 100 110 pF1KB8 RMCVGNRHGLLVPNNTTDQELQHIRNSLP--DTVQIRRVEERLSALGNVTTCNDY--VAL . :.: : .. . . . :: :.. : : :. :. .: NP_852 EACAG------VKSSGSGR----VPAPLPRHHRVHVPTVCSRASSPIPSPWCTRLSPAAA 50 60 70 80 90 120 130 140 150 160 170 pF1KB8 VHPDLDRETEEILADVLKVEVFRQTVADQVLVGSYCVFSNQGGLVHPKTSIEDQDELSSL ::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_852 SSGACVWETEEILADVLKVEVFRQTVADQVLVGSYCVFSNQGGLVHPKTSIEDQDELSSL 100 110 120 130 140 150 180 190 200 210 220 230 pF1KB8 LQVPLVAGTVNRGSEVIAAGMVVNDWCAFCGLDTTSTELSVVESVFKLNEAQPSTIATSM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_852 LQVPLVAGTVNRGSEVIAAGMVVNDWCAFCGLDTTSTELSVVESVFKLNEAQPSTIATSM 160 170 180 190 200 210 240 pF1KB8 RDSLIDSLT ::::::::: NP_852 RDSLIDSLT 220 245 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 10:57:34 2016 done: Fri Nov 4 10:57:35 2016 Total Scan time: 5.290 Total Display time: -0.020 Function used was FASTA [36.3.4 Apr, 2011]