FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB8249, 239 aa 1>>>pF1KB8249 239 - 239 aa - 239 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.5905+/-0.000417; mu= 8.9718+/- 0.026 mean_var=101.7615+/-20.055, 0's: 0 Z-trim(113.4): 25 B-trim: 1088 in 2/50 Lambda= 0.127140 statistics sampled from 22668 (22681) to 22668 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.617), E-opt: 0.2 (0.266), width: 16 Scan time: 5.510 The best scores are: opt bits E(85289) NP_063940 (OMIM: 605219,614152) diablo homolog, mi ( 239) 1507 286.7 2.4e-77 NP_620308 (OMIM: 605219,614152) diablo homolog, mi ( 186) 1090 210.2 2.1e-54 NP_001265233 (OMIM: 605219,614152) diablo homolog, ( 186) 1090 210.2 2.1e-54 NP_001265232 (OMIM: 605219,614152) diablo homolog, ( 166) 1010 195.5 4.9e-50 NP_001265231 (OMIM: 605219,614152) diablo homolog, ( 142) 835 163.3 2e-40 NP_001265271 (OMIM: 605219,614152) diablo homolog, ( 195) 829 162.3 5.6e-40 >>NP_063940 (OMIM: 605219,614152) diablo homolog, mitoch (239 aa) initn: 1507 init1: 1507 opt: 1507 Z-score: 1509.6 bits: 286.7 E(85289): 2.4e-77 Smith-Waterman score: 1507; 100.0% identity (100.0% similar) in 239 aa overlap (1-239:1-239) 10 20 30 40 50 60 pF1KB8 MAALKSWLSRSVTSFFRYRQCLCVPVVANFKKRCFSELIRPWHKTVTIGFGVTLCAVPIA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_063 MAALKSWLSRSVTSFFRYRQCLCVPVVANFKKRCFSELIRPWHKTVTIGFGVTLCAVPIA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 QKSEPHSLSSEALMRRAVSLVTDSTSTFLSQTTYALIEAITEYTKAVYTLTSLYRQYTSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_063 QKSEPHSLSSEALMRRAVSLVTDSTSTFLSQTTYALIEAITEYTKAVYTLTSLYRQYTSL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 LGKMNSEEEDEVWQVIIGARAEMTSKHQEYLKLETTWMTAVGLSEMAAEAAYQTGADQAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_063 LGKMNSEEEDEVWQVIIGARAEMTSKHQEYLKLETTWMTAVGLSEMAAEAAYQTGADQAS 130 140 150 160 170 180 190 200 210 220 230 pF1KB8 ITARNHIQLVKLQVEEVHQLSRKAETKLAEAQIEELRQKTQEEGEERAESEQEAYLRED ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_063 ITARNHIQLVKLQVEEVHQLSRKAETKLAEAQIEELRQKTQEEGEERAESEQEAYLRED 190 200 210 220 230 >>NP_620308 (OMIM: 605219,614152) diablo homolog, mitoch (186 aa) initn: 1090 init1: 1090 opt: 1090 Z-score: 1097.8 bits: 210.2 E(85289): 2.1e-54 Smith-Waterman score: 1090; 100.0% identity (100.0% similar) in 179 aa overlap (61-239:8-186) 40 50 60 70 80 90 pF1KB8 KKRCFSELIRPWHKTVTIGFGVTLCAVPIAQKSEPHSLSSEALMRRAVSLVTDSTSTFLS :::::::::::::::::::::::::::::: NP_620 MKSDFYFQKSEPHSLSSEALMRRAVSLVTDSTSTFLS 10 20 30 100 110 120 130 140 150 pF1KB8 QTTYALIEAITEYTKAVYTLTSLYRQYTSLLGKMNSEEEDEVWQVIIGARAEMTSKHQEY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_620 QTTYALIEAITEYTKAVYTLTSLYRQYTSLLGKMNSEEEDEVWQVIIGARAEMTSKHQEY 40 50 60 70 80 90 160 170 180 190 200 210 pF1KB8 LKLETTWMTAVGLSEMAAEAAYQTGADQASITARNHIQLVKLQVEEVHQLSRKAETKLAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_620 LKLETTWMTAVGLSEMAAEAAYQTGADQASITARNHIQLVKLQVEEVHQLSRKAETKLAE 100 110 120 130 140 150 220 230 pF1KB8 AQIEELRQKTQEEGEERAESEQEAYLRED ::::::::::::::::::::::::::::: NP_620 AQIEELRQKTQEEGEERAESEQEAYLRED 160 170 180 >>NP_001265233 (OMIM: 605219,614152) diablo homolog, mit (186 aa) initn: 1090 init1: 1090 opt: 1090 Z-score: 1097.8 bits: 210.2 E(85289): 2.1e-54 Smith-Waterman score: 1090; 100.0% identity (100.0% similar) in 179 aa overlap (61-239:8-186) 40 50 60 70 80 90 pF1KB8 KKRCFSELIRPWHKTVTIGFGVTLCAVPIAQKSEPHSLSSEALMRRAVSLVTDSTSTFLS :::::::::::::::::::::::::::::: NP_001 MKSDFYFQKSEPHSLSSEALMRRAVSLVTDSTSTFLS 10 20 30 100 110 120 130 140 150 pF1KB8 QTTYALIEAITEYTKAVYTLTSLYRQYTSLLGKMNSEEEDEVWQVIIGARAEMTSKHQEY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QTTYALIEAITEYTKAVYTLTSLYRQYTSLLGKMNSEEEDEVWQVIIGARAEMTSKHQEY 40 50 60 70 80 90 160 170 180 190 200 210 pF1KB8 LKLETTWMTAVGLSEMAAEAAYQTGADQASITARNHIQLVKLQVEEVHQLSRKAETKLAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LKLETTWMTAVGLSEMAAEAAYQTGADQASITARNHIQLVKLQVEEVHQLSRKAETKLAE 100 110 120 130 140 150 220 230 pF1KB8 AQIEELRQKTQEEGEERAESEQEAYLRED ::::::::::::::::::::::::::::: NP_001 AQIEELRQKTQEEGEERAESEQEAYLRED 160 170 180 >>NP_001265232 (OMIM: 605219,614152) diablo homolog, mit (166 aa) initn: 1010 init1: 1010 opt: 1010 Z-score: 1019.3 bits: 195.5 E(85289): 4.9e-50 Smith-Waterman score: 1010; 100.0% identity (100.0% similar) in 166 aa overlap (74-239:1-166) 50 60 70 80 90 100 pF1KB8 KTVTIGFGVTLCAVPIAQKSEPHSLSSEALMRRAVSLVTDSTSTFLSQTTYALIEAITEY :::::::::::::::::::::::::::::: NP_001 MRRAVSLVTDSTSTFLSQTTYALIEAITEY 10 20 30 110 120 130 140 150 160 pF1KB8 TKAVYTLTSLYRQYTSLLGKMNSEEEDEVWQVIIGARAEMTSKHQEYLKLETTWMTAVGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TKAVYTLTSLYRQYTSLLGKMNSEEEDEVWQVIIGARAEMTSKHQEYLKLETTWMTAVGL 40 50 60 70 80 90 170 180 190 200 210 220 pF1KB8 SEMAAEAAYQTGADQASITARNHIQLVKLQVEEVHQLSRKAETKLAEAQIEELRQKTQEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SEMAAEAAYQTGADQASITARNHIQLVKLQVEEVHQLSRKAETKLAEAQIEELRQKTQEE 100 110 120 130 140 150 230 pF1KB8 GEERAESEQEAYLRED :::::::::::::::: NP_001 GEERAESEQEAYLRED 160 >>NP_001265231 (OMIM: 605219,614152) diablo homolog, mit (142 aa) initn: 835 init1: 835 opt: 835 Z-score: 846.8 bits: 163.3 E(85289): 2e-40 Smith-Waterman score: 835; 98.5% identity (99.3% similar) in 137 aa overlap (103-239:6-142) 80 90 100 110 120 130 pF1KB8 LMRRAVSLVTDSTSTFLSQTTYALIEAITEYTKAVYTLTSLYRQYTSLLGKMNSEEEDEV : .::::::::::::::::::::::::::: NP_001 MKSDFYFQAVYTLTSLYRQYTSLLGKMNSEEEDEV 10 20 30 140 150 160 170 180 190 pF1KB8 WQVIIGARAEMTSKHQEYLKLETTWMTAVGLSEMAAEAAYQTGADQASITARNHIQLVKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 WQVIIGARAEMTSKHQEYLKLETTWMTAVGLSEMAAEAAYQTGADQASITARNHIQLVKL 40 50 60 70 80 90 200 210 220 230 pF1KB8 QVEEVHQLSRKAETKLAEAQIEELRQKTQEEGEERAESEQEAYLRED ::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QVEEVHQLSRKAETKLAEAQIEELRQKTQEEGEERAESEQEAYLRED 100 110 120 130 140 >>NP_001265271 (OMIM: 605219,614152) diablo homolog, mit (195 aa) initn: 829 init1: 829 opt: 829 Z-score: 838.8 bits: 162.3 E(85289): 5.6e-40 Smith-Waterman score: 1153; 81.6% identity (81.6% similar) in 239 aa overlap (1-239:1-195) 10 20 30 40 50 60 pF1KB8 MAALKSWLSRSVTSFFRYRQCLCVPVVANFKKRCFSELIRPWHKTVTIGFGVTLCAVPIA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MAALKSWLSRSVTSFFRYRQCLCVPVVANFKKRCFSELIRPWHKTVTIGFGVTLCAVPIA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 QKSEPHSLSSEALMRRAVSLVTDSTSTFLSQTTYALIEAITEYTKAVYTLTSLYRQYTSL : ::::::::::::::: NP_001 Q--------------------------------------------AVYTLTSLYRQYTSL 70 130 140 150 160 170 180 pF1KB8 LGKMNSEEEDEVWQVIIGARAEMTSKHQEYLKLETTWMTAVGLSEMAAEAAYQTGADQAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LGKMNSEEEDEVWQVIIGARAEMTSKHQEYLKLETTWMTAVGLSEMAAEAAYQTGADQAS 80 90 100 110 120 130 190 200 210 220 230 pF1KB8 ITARNHIQLVKLQVEEVHQLSRKAETKLAEAQIEELRQKTQEEGEERAESEQEAYLRED ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ITARNHIQLVKLQVEEVHQLSRKAETKLAEAQIEELRQKTQEEGEERAESEQEAYLRED 140 150 160 170 180 190 239 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 11:00:07 2016 done: Fri Nov 4 11:00:08 2016 Total Scan time: 5.510 Total Display time: -0.030 Function used was FASTA [36.3.4 Apr, 2011]