Result of FASTA (omim) for
pF1KB8251
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB8251, 227 aa
1>>>pF1KB8251 227 - 227 aa - 227 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.1154+/-0.000409; mu= 10.9092+/- 0.025
mean_var=97.2915+/-19.178, 0's: 0 Z-trim(113.4): 41 B-trim: 163 in 2/49
Lambda= 0.130028
statistics sampled from 22628 (22655) to 22628 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.63), E-opt: 0.2 (0.266), width: 16
Scan time: 4.990
The best scores are: opt bits E(85289)
NP_006521 (OMIM: 602116) YEATS domain-containing p ( 227) 1483 288.3 7.1e-78
NP_001287879 (OMIM: 602116) YEATS domain-containin ( 173) 731 147.2 1.7e-35
XP_016862301 (OMIM: 613373) PREDICTED: YEATS domai (1033) 288 64.6 7.1e-10
XP_011511268 (OMIM: 613373) PREDICTED: YEATS domai (1034) 288 64.6 7.1e-10
XP_016862300 (OMIM: 613373) PREDICTED: YEATS domai (1370) 288 64.7 8.9e-10
XP_016862299 (OMIM: 613373) PREDICTED: YEATS domai (1422) 288 64.7 9.2e-10
NP_060493 (OMIM: 613373) YEATS domain-containing p (1422) 288 64.7 9.2e-10
XP_016862298 (OMIM: 613373) PREDICTED: YEATS domai (1422) 288 64.7 9.2e-10
XP_006713751 (OMIM: 613373) PREDICTED: YEATS domai (1423) 288 64.7 9.2e-10
XP_005247655 (OMIM: 613373) PREDICTED: YEATS domai (1423) 288 64.7 9.2e-10
XP_005247654 (OMIM: 613373) PREDICTED: YEATS domai (1423) 288 64.7 9.2e-10
XP_011526325 (OMIM: 159556) PREDICTED: protein ENL ( 558) 223 52.2 2e-06
XP_016870216 (OMIM: 159558) PREDICTED: protein AF- ( 517) 209 49.6 1.2e-05
XP_016870215 (OMIM: 159558) PREDICTED: protein AF- ( 520) 209 49.6 1.2e-05
NP_001273620 (OMIM: 159558) protein AF-9 isoform b ( 565) 209 49.6 1.3e-05
NP_004520 (OMIM: 159558) protein AF-9 isoform a [H ( 568) 209 49.6 1.3e-05
NP_005925 (OMIM: 159556) protein ENL [Homo sapiens ( 559) 208 49.4 1.4e-05
XP_011526324 (OMIM: 159556) PREDICTED: protein ENL ( 561) 208 49.4 1.4e-05
XP_011526323 (OMIM: 159556) PREDICTED: protein ENL ( 600) 208 49.4 1.5e-05
XP_016882308 (OMIM: 159556) PREDICTED: protein ENL ( 527) 163 41.0 0.0048
>>NP_006521 (OMIM: 602116) YEATS domain-containing prote (227 aa)
initn: 1483 init1: 1483 opt: 1483 Z-score: 1519.1 bits: 288.3 E(85289): 7.1e-78
Smith-Waterman score: 1483; 100.0% identity (100.0% similar) in 227 aa overlap (1-227:1-227)
10 20 30 40 50 60
pF1KB8 MFKRMAEFGPDSGGRVKGVTIVKPIVYGNVARYFGKKREEDGHTHQWTVYVKPYRNEDMS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 MFKRMAEFGPDSGGRVKGVTIVKPIVYGNVARYFGKKREEDGHTHQWTVYVKPYRNEDMS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 AYVKKIQFKLHESYGNPLRVVTKPPYEITETGWGEFEIIIKIFFIDPNERPVTLYHLLKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 AYVKKIQFKLHESYGNPLRVVTKPPYEITETGWGEFEIIIKIFFIDPNERPVTLYHLLKL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 FQSDTNAMLGKKTVVSEFYDEMIFQDPTAMMQQLLTTSRQLTLGAYKHETEFAELEVKTR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 FQSDTNAMLGKKTVVSEFYDEMIFQDPTAMMQQLLTTSRQLTLGAYKHETEFAELEVKTR
130 140 150 160 170 180
190 200 210 220
pF1KB8 EKLEAAKKKTSFEIAELKERLKASRETINCLKNEIRKLEEDDQAKDI
:::::::::::::::::::::::::::::::::::::::::::::::
NP_006 EKLEAAKKKTSFEIAELKERLKASRETINCLKNEIRKLEEDDQAKDI
190 200 210 220
>>NP_001287879 (OMIM: 602116) YEATS domain-containing pr (173 aa)
initn: 729 init1: 729 opt: 731 Z-score: 758.4 bits: 147.2 E(85289): 1.7e-35
Smith-Waterman score: 996; 76.2% identity (76.2% similar) in 227 aa overlap (1-227:1-173)
10 20 30 40 50 60
pF1KB8 MFKRMAEFGPDSGGRVKGVTIVKPIVYGNVARYFGKKREEDGHTHQWTVYVKPYRNEDMS
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MFKRMAEFGPDSGGRVKGVTIVKPIVYGNVARYFGKKREEDGHTHQWTVYVKPYRNE---
10 20 30 40 50
70 80 90 100 110 120
pF1KB8 AYVKKIQFKLHESYGNPLRVVTKPPYEITETGWGEFEIIIKIFFIDPNERPVTLYHLLKL
:::::::::
NP_001 ---------------------------------------------------VTLYHLLKL
60
130 140 150 160 170 180
pF1KB8 FQSDTNAMLGKKTVVSEFYDEMIFQDPTAMMQQLLTTSRQLTLGAYKHETEFAELEVKTR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FQSDTNAMLGKKTVVSEFYDEMIFQDPTAMMQQLLTTSRQLTLGAYKHETEFAELEVKTR
70 80 90 100 110 120
190 200 210 220
pF1KB8 EKLEAAKKKTSFEIAELKERLKASRETINCLKNEIRKLEEDDQAKDI
:::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EKLEAAKKKTSFEIAELKERLKASRETINCLKNEIRKLEEDDQAKDI
130 140 150 160 170
>>XP_016862301 (OMIM: 613373) PREDICTED: YEATS domain-co (1033 aa)
initn: 208 init1: 126 opt: 288 Z-score: 298.2 bits: 64.6 E(85289): 7.1e-10
Smith-Waterman score: 288; 38.6% identity (68.2% similar) in 132 aa overlap (21-146:206-337)
10 20 30 40
pF1KB8 MFKRMAEFGPDSGGRVKGVTIVKPIVYGNVARYF--GKKREEDGHTHQWT
. : :: :::..:. :..:.: ::.:
XP_016 NTGRDTSRITGSHKTEQRNADLTDETSRLFVKKTIVVGNVSKYIPPDKREENDQSTHKWM
180 190 200 210 220 230
50 60 70 80 90 100
pF1KB8 VYVKPYRNE-DMSAYVKKIQFKLHESYG-NPLRVVTKPPYEITETGWGEFEIIIKIFFID
:::. : : ... .:::. : :: :: : : : .::...:. ::::: . ... : :
XP_016 VYVRGSRREPSINHFVKKVWFFLHPSYKPNDLVEVREPPFHLTRRGWGEFPVRVQVHFKD
240 250 260 270 280 290
110 120 130 140 150 160
pF1KB8 PNERPVTLYHLLKLFQSDTNAM-LGKKTVVS-EFYDEMIFQDPTAMMQQLLTTSRQLTLG
... . . : ::: .. :. . :: .:::. :.. . . .:
XP_016 SQNKRIDIIHNLKLDRTYTGLQTLGAETVVDVELHRHSLGEDCIYPQSSESDISDAPPSL
300 310 320 330 340 350
170 180 190 200 210 220
pF1KB8 AYKHETEFAELEVKTREKLEAAKKKTSFEIAELKERLKASRETINCLKNEIRKLEEDDQA
XP_016 PLTIPAPVKASSPIKQSHEPVPDTSVEKGFPASTEAERHTPFYALPSSLERTPTKMTTSQ
360 370 380 390 400 410
>>XP_011511268 (OMIM: 613373) PREDICTED: YEATS domain-co (1034 aa)
initn: 208 init1: 126 opt: 288 Z-score: 298.2 bits: 64.6 E(85289): 7.1e-10
Smith-Waterman score: 288; 38.6% identity (68.2% similar) in 132 aa overlap (21-146:206-337)
10 20 30 40
pF1KB8 MFKRMAEFGPDSGGRVKGVTIVKPIVYGNVARYF--GKKREEDGHTHQWT
. : :: :::..:. :..:.: ::.:
XP_011 NTGRDTSRITGSHKTEQRNADLTDETSRLFVKKTIVVGNVSKYIPPDKREENDQSTHKWM
180 190 200 210 220 230
50 60 70 80 90 100
pF1KB8 VYVKPYRNE-DMSAYVKKIQFKLHESYG-NPLRVVTKPPYEITETGWGEFEIIIKIFFID
:::. : : ... .:::. : :: :: : : : .::...:. ::::: . ... : :
XP_011 VYVRGSRREPSINHFVKKVWFFLHPSYKPNDLVEVREPPFHLTRRGWGEFPVRVQVHFKD
240 250 260 270 280 290
110 120 130 140 150 160
pF1KB8 PNERPVTLYHLLKLFQSDTNAM-LGKKTVVS-EFYDEMIFQDPTAMMQQLLTTSRQLTLG
... . . : ::: .. :. . :: .:::. :.. . . .:
XP_011 SQNKRIDIIHNLKLDRTYTGLQTLGAETVVDVELHRHSLGEDCIYPQSSESDISDAPPSL
300 310 320 330 340 350
170 180 190 200 210 220
pF1KB8 AYKHETEFAELEVKTREKLEAAKKKTSFEIAELKERLKASRETINCLKNEIRKLEEDDQA
XP_011 PLTIPAPVKASSPIKQSHEPVPDTSVEKAGFPASTEAERHTPFYALPSSLERTPTKMTTS
360 370 380 390 400 410
>>XP_016862300 (OMIM: 613373) PREDICTED: YEATS domain-co (1370 aa)
initn: 236 init1: 126 opt: 288 Z-score: 296.5 bits: 64.7 E(85289): 8.9e-10
Smith-Waterman score: 288; 38.6% identity (68.2% similar) in 132 aa overlap (21-146:153-284)
10 20 30 40
pF1KB8 MFKRMAEFGPDSGGRVKGVTIVKPIVYGNVARYF--GKKREEDGHTHQWT
. : :: :::..:. :..:.: ::.:
XP_016 NTGRDTSRITGSHKTEQRNADLTDETSRLFVKKTIVVGNVSKYIPPDKREENDQSTHKWM
130 140 150 160 170 180
50 60 70 80 90 100
pF1KB8 VYVKPYRNE-DMSAYVKKIQFKLHESYG-NPLRVVTKPPYEITETGWGEFEIIIKIFFID
:::. : : ... .:::. : :: :: : : : .::...:. ::::: . ... : :
XP_016 VYVRGSRREPSINHFVKKVWFFLHPSYKPNDLVEVREPPFHLTRRGWGEFPVRVQVHFKD
190 200 210 220 230 240
110 120 130 140 150 160
pF1KB8 PNERPVTLYHLLKLFQSDTNAM-LGKKTVVS-EFYDEMIFQDPTAMMQQLLTTSRQLTLG
... . . : ::: .. :. . :: .:::. :.. . . .:
XP_016 SQNKRIDIIHNLKLDRTYTGLQTLGAETVVDVELHRHSLGEDCIYPQSSESDISDAPPSL
250 260 270 280 290 300
170 180 190 200 210 220
pF1KB8 AYKHETEFAELEVKTREKLEAAKKKTSFEIAELKERLKASRETINCLKNEIRKLEEDDQA
XP_016 PLTIPAPVKASSPIKQSHEPVPDTSVEKAGFPASTEAERHTPFYALPSSLERTPTKMTTS
310 320 330 340 350 360
>>XP_016862299 (OMIM: 613373) PREDICTED: YEATS domain-co (1422 aa)
initn: 236 init1: 126 opt: 288 Z-score: 296.2 bits: 64.7 E(85289): 9.2e-10
Smith-Waterman score: 288; 38.6% identity (68.2% similar) in 132 aa overlap (21-146:206-337)
10 20 30 40
pF1KB8 MFKRMAEFGPDSGGRVKGVTIVKPIVYGNVARYF--GKKREEDGHTHQWT
. : :: :::..:. :..:.: ::.:
XP_016 NTGRDTSRITGSHKTEQRNADLTDETSRLFVKKTIVVGNVSKYIPPDKREENDQSTHKWM
180 190 200 210 220 230
50 60 70 80 90 100
pF1KB8 VYVKPYRNE-DMSAYVKKIQFKLHESYG-NPLRVVTKPPYEITETGWGEFEIIIKIFFID
:::. : : ... .:::. : :: :: : : : .::...:. ::::: . ... : :
XP_016 VYVRGSRREPSINHFVKKVWFFLHPSYKPNDLVEVREPPFHLTRRGWGEFPVRVQVHFKD
240 250 260 270 280 290
110 120 130 140 150 160
pF1KB8 PNERPVTLYHLLKLFQSDTNAM-LGKKTVVS-EFYDEMIFQDPTAMMQQLLTTSRQLTLG
... . . : ::: .. :. . :: .:::. :.. . . .:
XP_016 SQNKRIDIIHNLKLDRTYTGLQTLGAETVVDVELHRHSLGEDCIYPQSSESDISDAPPSL
300 310 320 330 340 350
170 180 190 200 210 220
pF1KB8 AYKHETEFAELEVKTREKLEAAKKKTSFEIAELKERLKASRETINCLKNEIRKLEEDDQA
XP_016 PLTIPAPVKASSPIKQSHEPVPDTSVEKGFPASTEAERHTPFYALPSSLERTPTKMTTSQ
360 370 380 390 400 410
>>NP_060493 (OMIM: 613373) YEATS domain-containing prote (1422 aa)
initn: 236 init1: 126 opt: 288 Z-score: 296.2 bits: 64.7 E(85289): 9.2e-10
Smith-Waterman score: 288; 38.6% identity (68.2% similar) in 132 aa overlap (21-146:206-337)
10 20 30 40
pF1KB8 MFKRMAEFGPDSGGRVKGVTIVKPIVYGNVARYF--GKKREEDGHTHQWT
. : :: :::..:. :..:.: ::.:
NP_060 NTGRDTSRITGSHKTEQRNADLTDETSRLFVKKTIVVGNVSKYIPPDKREENDQSTHKWM
180 190 200 210 220 230
50 60 70 80 90 100
pF1KB8 VYVKPYRNE-DMSAYVKKIQFKLHESYG-NPLRVVTKPPYEITETGWGEFEIIIKIFFID
:::. : : ... .:::. : :: :: : : : .::...:. ::::: . ... : :
NP_060 VYVRGSRREPSINHFVKKVWFFLHPSYKPNDLVEVREPPFHLTRRGWGEFPVRVQVHFKD
240 250 260 270 280 290
110 120 130 140 150 160
pF1KB8 PNERPVTLYHLLKLFQSDTNAM-LGKKTVVS-EFYDEMIFQDPTAMMQQLLTTSRQLTLG
... . . : ::: .. :. . :: .:::. :.. . . .:
NP_060 SQNKRIDIIHNLKLDRTYTGLQTLGAETVVDVELHRHSLGEDCIYPQSSESDISDAPPSL
300 310 320 330 340 350
170 180 190 200 210 220
pF1KB8 AYKHETEFAELEVKTREKLEAAKKKTSFEIAELKERLKASRETINCLKNEIRKLEEDDQA
NP_060 PLTIPAPVKASSPIKQSHEPVPDTSVEKGFPASTEAERHTPFYALPSSLERTPTKMTTSQ
360 370 380 390 400 410
>>XP_016862298 (OMIM: 613373) PREDICTED: YEATS domain-co (1422 aa)
initn: 236 init1: 126 opt: 288 Z-score: 296.2 bits: 64.7 E(85289): 9.2e-10
Smith-Waterman score: 288; 38.6% identity (68.2% similar) in 132 aa overlap (21-146:206-337)
10 20 30 40
pF1KB8 MFKRMAEFGPDSGGRVKGVTIVKPIVYGNVARYF--GKKREEDGHTHQWT
. : :: :::..:. :..:.: ::.:
XP_016 NTGRDTSRITGSHKTEQRNADLTDETSRLFVKKTIVVGNVSKYIPPDKREENDQSTHKWM
180 190 200 210 220 230
50 60 70 80 90 100
pF1KB8 VYVKPYRNE-DMSAYVKKIQFKLHESYG-NPLRVVTKPPYEITETGWGEFEIIIKIFFID
:::. : : ... .:::. : :: :: : : : .::...:. ::::: . ... : :
XP_016 VYVRGSRREPSINHFVKKVWFFLHPSYKPNDLVEVREPPFHLTRRGWGEFPVRVQVHFKD
240 250 260 270 280 290
110 120 130 140 150 160
pF1KB8 PNERPVTLYHLLKLFQSDTNAM-LGKKTVVS-EFYDEMIFQDPTAMMQQLLTTSRQLTLG
... . . : ::: .. :. . :: .:::. :.. . . .:
XP_016 SQNKRIDIIHNLKLDRTYTGLQTLGAETVVDVELHRHSLGEDCIYPQSSESDISDAPPSL
300 310 320 330 340 350
170 180 190 200 210 220
pF1KB8 AYKHETEFAELEVKTREKLEAAKKKTSFEIAELKERLKASRETINCLKNEIRKLEEDDQA
XP_016 PLTIPAPVKASSPIKQSHEPVPDTSVEKGFPASTEAERHTPFYALPSSLERTPTKMTTSQ
360 370 380 390 400 410
>>XP_006713751 (OMIM: 613373) PREDICTED: YEATS domain-co (1423 aa)
initn: 236 init1: 126 opt: 288 Z-score: 296.2 bits: 64.7 E(85289): 9.2e-10
Smith-Waterman score: 288; 38.6% identity (68.2% similar) in 132 aa overlap (21-146:206-337)
10 20 30 40
pF1KB8 MFKRMAEFGPDSGGRVKGVTIVKPIVYGNVARYF--GKKREEDGHTHQWT
. : :: :::..:. :..:.: ::.:
XP_006 NTGRDTSRITGSHKTEQRNADLTDETSRLFVKKTIVVGNVSKYIPPDKREENDQSTHKWM
180 190 200 210 220 230
50 60 70 80 90 100
pF1KB8 VYVKPYRNE-DMSAYVKKIQFKLHESYG-NPLRVVTKPPYEITETGWGEFEIIIKIFFID
:::. : : ... .:::. : :: :: : : : .::...:. ::::: . ... : :
XP_006 VYVRGSRREPSINHFVKKVWFFLHPSYKPNDLVEVREPPFHLTRRGWGEFPVRVQVHFKD
240 250 260 270 280 290
110 120 130 140 150 160
pF1KB8 PNERPVTLYHLLKLFQSDTNAM-LGKKTVVS-EFYDEMIFQDPTAMMQQLLTTSRQLTLG
... . . : ::: .. :. . :: .:::. :.. . . .:
XP_006 SQNKRIDIIHNLKLDRTYTGLQTLGAETVVDVELHRHSLGEDCIYPQSSESDISDAPPSL
300 310 320 330 340 350
170 180 190 200 210 220
pF1KB8 AYKHETEFAELEVKTREKLEAAKKKTSFEIAELKERLKASRETINCLKNEIRKLEEDDQA
XP_006 PLTIPAPVKASSPIKQSHEPVPDTSVEKAGFPASTEAERHTPFYALPSSLERTPTKMTTS
360 370 380 390 400 410
>>XP_005247655 (OMIM: 613373) PREDICTED: YEATS domain-co (1423 aa)
initn: 236 init1: 126 opt: 288 Z-score: 296.2 bits: 64.7 E(85289): 9.2e-10
Smith-Waterman score: 288; 38.6% identity (68.2% similar) in 132 aa overlap (21-146:206-337)
10 20 30 40
pF1KB8 MFKRMAEFGPDSGGRVKGVTIVKPIVYGNVARYF--GKKREEDGHTHQWT
. : :: :::..:. :..:.: ::.:
XP_005 NTGRDTSRITGSHKTEQRNADLTDETSRLFVKKTIVVGNVSKYIPPDKREENDQSTHKWM
180 190 200 210 220 230
50 60 70 80 90 100
pF1KB8 VYVKPYRNE-DMSAYVKKIQFKLHESYG-NPLRVVTKPPYEITETGWGEFEIIIKIFFID
:::. : : ... .:::. : :: :: : : : .::...:. ::::: . ... : :
XP_005 VYVRGSRREPSINHFVKKVWFFLHPSYKPNDLVEVREPPFHLTRRGWGEFPVRVQVHFKD
240 250 260 270 280 290
110 120 130 140 150 160
pF1KB8 PNERPVTLYHLLKLFQSDTNAM-LGKKTVVS-EFYDEMIFQDPTAMMQQLLTTSRQLTLG
... . . : ::: .. :. . :: .:::. :.. . . .:
XP_005 SQNKRIDIIHNLKLDRTYTGLQTLGAETVVDVELHRHSLGEDCIYPQSSESDISDAPPSL
300 310 320 330 340 350
170 180 190 200 210 220
pF1KB8 AYKHETEFAELEVKTREKLEAAKKKTSFEIAELKERLKASRETINCLKNEIRKLEEDDQA
XP_005 PLTIPAPVKASSPIKQSHEPVPDTSVEKAGFPASTEAERHTPFYALPSSLERTPTKMTTS
360 370 380 390 400 410
227 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 11:02:09 2016 done: Fri Nov 4 11:02:10 2016
Total Scan time: 4.990 Total Display time: 0.010
Function used was FASTA [36.3.4 Apr, 2011]