FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB8252, 335 aa 1>>>pF1KB8252 335 - 335 aa - 335 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.3532+/-0.00109; mu= 15.3378+/- 0.065 mean_var=58.0111+/-11.458, 0's: 0 Z-trim(101.2): 33 B-trim: 0 in 0/50 Lambda= 0.168391 statistics sampled from 6427 (6434) to 6427 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.565), E-opt: 0.2 (0.198), width: 16 Scan time: 1.330 The best scores are: opt bits E(32554) CCDS8549.1 GAPDH gene_id:2597|Hs108|chr12 ( 335) 2198 542.6 1.6e-154 CCDS58201.1 GAPDH gene_id:2597|Hs108|chr12 ( 293) 1925 476.3 1.3e-134 CCDS12465.1 GAPDHS gene_id:26330|Hs108|chr19 ( 408) 1538 382.3 3.6e-106 >>CCDS8549.1 GAPDH gene_id:2597|Hs108|chr12 (335 aa) initn: 2198 init1: 2198 opt: 2198 Z-score: 2887.5 bits: 542.6 E(32554): 1.6e-154 Smith-Waterman score: 2198; 100.0% identity (100.0% similar) in 335 aa overlap (1-335:1-335) 10 20 30 40 50 60 pF1KB8 MGKVKVGVNGFGRIGRLVTRAAFNSGKVDIVAINDPFIDLNYMVYMFQYDSTHGKFHGTV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS85 MGKVKVGVNGFGRIGRLVTRAAFNSGKVDIVAINDPFIDLNYMVYMFQYDSTHGKFHGTV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 KAENGKLVINGNPITIFQERDPSKIKWGDAGAEYVVESTGVFTTMEKAGAHLQGGAKRVI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS85 KAENGKLVINGNPITIFQERDPSKIKWGDAGAEYVVESTGVFTTMEKAGAHLQGGAKRVI 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 ISAPSADAPMFVMGVNHEKYDNSLKIISNASCTTNCLAPLAKVIHDNFGIVEGLMTTVHA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS85 ISAPSADAPMFVMGVNHEKYDNSLKIISNASCTTNCLAPLAKVIHDNFGIVEGLMTTVHA 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 ITATQKTVDGPSGKLWRDGRGALQNIIPASTGAAKAVGKVIPELNGKLTGMAFRVPTANV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS85 ITATQKTVDGPSGKLWRDGRGALQNIIPASTGAAKAVGKVIPELNGKLTGMAFRVPTANV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 SVVDLTCRLEKPAKYDDIKKVVKQASEGPLKGILGYTEHQVVSSDFNSDTHSSTFDAGAG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS85 SVVDLTCRLEKPAKYDDIKKVVKQASEGPLKGILGYTEHQVVSSDFNSDTHSSTFDAGAG 250 260 270 280 290 300 310 320 330 pF1KB8 IALNDHFVKLISWYDNEFGYSNRVVDLMAHMASKE ::::::::::::::::::::::::::::::::::: CCDS85 IALNDHFVKLISWYDNEFGYSNRVVDLMAHMASKE 310 320 330 >>CCDS58201.1 GAPDH gene_id:2597|Hs108|chr12 (293 aa) initn: 1925 init1: 1925 opt: 1925 Z-score: 2530.0 bits: 476.3 E(32554): 1.3e-134 Smith-Waterman score: 1925; 100.0% identity (100.0% similar) in 293 aa overlap (43-335:1-293) 20 30 40 50 60 70 pF1KB8 RIGRLVTRAAFNSGKVDIVAINDPFIDLNYMVYMFQYDSTHGKFHGTVKAENGKLVINGN :::::::::::::::::::::::::::::: CCDS58 MVYMFQYDSTHGKFHGTVKAENGKLVINGN 10 20 30 80 90 100 110 120 130 pF1KB8 PITIFQERDPSKIKWGDAGAEYVVESTGVFTTMEKAGAHLQGGAKRVIISAPSADAPMFV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 PITIFQERDPSKIKWGDAGAEYVVESTGVFTTMEKAGAHLQGGAKRVIISAPSADAPMFV 40 50 60 70 80 90 140 150 160 170 180 190 pF1KB8 MGVNHEKYDNSLKIISNASCTTNCLAPLAKVIHDNFGIVEGLMTTVHAITATQKTVDGPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 MGVNHEKYDNSLKIISNASCTTNCLAPLAKVIHDNFGIVEGLMTTVHAITATQKTVDGPS 100 110 120 130 140 150 200 210 220 230 240 250 pF1KB8 GKLWRDGRGALQNIIPASTGAAKAVGKVIPELNGKLTGMAFRVPTANVSVVDLTCRLEKP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 GKLWRDGRGALQNIIPASTGAAKAVGKVIPELNGKLTGMAFRVPTANVSVVDLTCRLEKP 160 170 180 190 200 210 260 270 280 290 300 310 pF1KB8 AKYDDIKKVVKQASEGPLKGILGYTEHQVVSSDFNSDTHSSTFDAGAGIALNDHFVKLIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 AKYDDIKKVVKQASEGPLKGILGYTEHQVVSSDFNSDTHSSTFDAGAGIALNDHFVKLIS 220 230 240 250 260 270 320 330 pF1KB8 WYDNEFGYSNRVVDLMAHMASKE ::::::::::::::::::::::: CCDS58 WYDNEFGYSNRVVDLMAHMASKE 280 290 >>CCDS12465.1 GAPDHS gene_id:26330|Hs108|chr19 (408 aa) initn: 1436 init1: 985 opt: 1538 Z-score: 2019.6 bits: 382.3 E(32554): 3.6e-106 Smith-Waterman score: 1538; 68.3% identity (88.9% similar) in 334 aa overlap (3-335:75-407) 10 20 30 pF1KB8 MGKVKVGVNGFGRIGRLVTRAAFNSGKVDIVA .. ::.:::::::::: :: ...: : .:: CCDS12 TPVREEIKPPPPPLPPHPATPPPKMVSVARELTVGINGFGRIGRLVLRACMEKG-VKVVA 50 60 70 80 90 100 40 50 60 70 80 90 pF1KB8 INDPFIDLNYMVYMFQYDSTHGKFHGTVKAENGKLVINGNPITIFQERDPSKIKWGDAGA .:::::: .::::::.::::::...:.:. .::.::.... :...: ..:..: : .:. CCDS12 VNDPFIDPEYMVYMFKYDSTHGRYKGSVEFRNGQLVVDNHEISVYQCKEPKQIPWRAVGS 110 120 130 140 150 160 100 110 120 130 140 150 pF1KB8 EYVVESTGVFTTMEKAGAHLQGGAKRVIISAPSADAPMFVMGVNHEKYD-NSLKIISNAS ::::::::. ... :. :...::.::.::::: ::::::::::.. :. .:..:.:::: CCDS12 PYVVESTGVYLSIQAASDHISAGAQRVVISAPSPDAPMFVMGVNENDYNPGSMNIVSNAS 170 180 190 200 210 220 160 170 180 190 200 210 pF1KB8 CTTNCLAPLAKVIHDNFGIVEGLMTTVHAITATQKTVDGPSGKLWRDGRGALQNIIPAST ::::::::::::::. ::::::::::::. ::::::::::: : ::::::: :::::::: CCDS12 CTTNCLAPLAKVIHERFGIVEGLMTTVHSYTATQKTVDGPSRKAWRDGRGAHQNIIPAST 230 240 250 260 270 280 220 230 240 250 260 270 pF1KB8 GAAKAVGKVIPELNGKLTGMAFRVPTANVSVVDLTCRLEKPAKYDDIKKVVKQASEGPLK :::::: ::::::.:::::::::::: .:::::::::: .:: :. ::..:: :..::. CCDS12 GAAKAVTKVIPELKGKLTGMAFRVPTPDVSVVDLTCRLAQPAPYSAIKEAVKAAAKGPMA 290 300 310 320 330 340 280 290 300 310 320 330 pF1KB8 GILGYTEHQVVSSDFNSDTHSSTFDAGAGIALNDHFVKLISWYDNEFGYSNRVVDLMAHM :::.::: .:::.:: .::::: ::: :::::::.:::::::::::.:::.:::::. .: CCDS12 GILAYTEDEVVSTDFLGDTHSSIFDAKAGIALNDNFVKLISWYDNEYGYSHRVVDLLRYM 350 360 370 380 390 400 pF1KB8 ASKE :.. CCDS12 FSRDK 335 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 11:02:51 2016 done: Fri Nov 4 11:02:51 2016 Total Scan time: 1.330 Total Display time: -0.010 Function used was FASTA [36.3.4 Apr, 2011]