FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB8255, 317 aa 1>>>pF1KB8255 317 - 317 aa - 317 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.5010+/-0.000497; mu= 9.4942+/- 0.030 mean_var=185.8908+/-40.106, 0's: 0 Z-trim(112.5): 452 B-trim: 188 in 2/47 Lambda= 0.094069 statistics sampled from 20795 (21390) to 20795 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.615), E-opt: 0.2 (0.251), width: 16 Scan time: 5.680 The best scores are: opt bits E(85289) NP_006089 (OMIM: 176981) receptor of activated pro ( 317) 2171 307.7 2e-83 NP_001186706 (OMIM: 614784,615973) POC1 centriolar ( 436) 416 69.7 1.2e-11 NP_002066 (OMIM: 139130,145500,617024) guanine nuc ( 340) 405 68.1 2.9e-11 XP_011519255 (OMIM: 139130,145500,617024) PREDICTE ( 360) 405 68.1 3.1e-11 XP_016861593 (OMIM: 614783,614813) PREDICTED: POC1 ( 321) 392 66.3 9.7e-11 NP_001155053 (OMIM: 614783,614813) POC1 centriolar ( 369) 392 66.4 1.1e-10 XP_016880191 (OMIM: 601545,607432) PREDICTED: plat ( 345) 388 65.8 1.5e-10 XP_016880188 (OMIM: 601545,607432) PREDICTED: plat ( 410) 388 65.9 1.6e-10 XP_016880189 (OMIM: 601545,607432) PREDICTED: plat ( 410) 388 65.9 1.6e-10 NP_000421 (OMIM: 601545,607432) platelet-activatin ( 410) 388 65.9 1.6e-10 XP_016880190 (OMIM: 601545,607432) PREDICTED: plat ( 410) 388 65.9 1.6e-10 XP_011522205 (OMIM: 601545,607432) PREDICTED: plat ( 428) 388 65.9 1.7e-10 XP_011522204 (OMIM: 601545,607432) PREDICTED: plat ( 428) 388 65.9 1.7e-10 XP_011522203 (OMIM: 601545,607432) PREDICTED: plat ( 428) 388 65.9 1.7e-10 NP_438172 (OMIM: 609012) WD repeat-containing prot ( 334) 364 62.5 1.4e-09 XP_005272220 (OMIM: 609012) PREDICTED: WD repeat-c ( 334) 364 62.5 1.4e-09 NP_060058 (OMIM: 609012) WD repeat-containing prot ( 334) 364 62.5 1.4e-09 XP_016856550 (OMIM: 139380,613065,616973) PREDICTE ( 340) 363 62.4 1.5e-09 XP_016856549 (OMIM: 139380,613065,616973) PREDICTE ( 340) 363 62.4 1.5e-09 XP_016856548 (OMIM: 139380,613065,616973) PREDICTE ( 340) 363 62.4 1.5e-09 NP_002065 (OMIM: 139380,613065,616973) guanine nuc ( 340) 363 62.4 1.5e-09 NP_001269468 (OMIM: 139380,613065,616973) guanine ( 340) 363 62.4 1.5e-09 NP_001151 (OMIM: 602233) apoptotic protease-activa (1194) 371 64.2 1.6e-09 NP_863658 (OMIM: 602233) apoptotic protease-activa (1205) 371 64.2 1.6e-09 XP_006713784 (OMIM: 610863,615185) PREDICTED: guan ( 340) 344 59.8 9.2e-09 XP_005247749 (OMIM: 610863,615185) PREDICTED: guan ( 340) 344 59.8 9.2e-09 NP_067642 (OMIM: 610863,615185) guanine nucleotide ( 340) 344 59.8 9.2e-09 NP_758440 (OMIM: 614784,615973) POC1 centriolar pr ( 478) 330 58.1 4.2e-08 XP_011531864 (OMIM: 614783,614813) PREDICTED: POC1 ( 300) 323 56.9 6.1e-08 XP_011531863 (OMIM: 614783,614813) PREDICTED: POC1 ( 326) 323 56.9 6.4e-08 NP_001155052 (OMIM: 614783,614813) POC1 centriolar ( 359) 323 57.0 6.8e-08 XP_011531862 (OMIM: 614783,614813) PREDICTED: POC1 ( 374) 323 57.0 7e-08 NP_056241 (OMIM: 614783,614813) POC1 centriolar pr ( 407) 323 57.1 7.4e-08 NP_037361 (OMIM: 602233) apoptotic protease-activa (1237) 330 58.6 7.5e-08 NP_863651 (OMIM: 602233) apoptotic protease-activa (1248) 330 58.6 7.6e-08 XP_011531866 (OMIM: 614783,614813) PREDICTED: POC1 ( 246) 318 56.1 8.7e-08 XP_011531867 (OMIM: 614783,614813) PREDICTED: POC1 ( 246) 318 56.1 8.7e-08 XP_011531865 (OMIM: 614783,614813) PREDICTED: POC1 ( 246) 318 56.1 8.7e-08 NP_001309196 (OMIM: 607795,615922) U4/U6 small nuc ( 279) 315 55.8 1.2e-07 NP_001309195 (OMIM: 607795,615922) U4/U6 small nuc ( 279) 315 55.8 1.2e-07 NP_001231855 (OMIM: 607795,615922) U4/U6 small nuc ( 521) 315 56.1 1.8e-07 NP_004688 (OMIM: 607795,615922) U4/U6 small nuclea ( 522) 315 56.1 1.8e-07 XP_016860390 (OMIM: 612173) PREDICTED: sperm-assoc ( 323) 308 54.9 2.6e-07 XP_011510137 (OMIM: 612173) PREDICTED: sperm-assoc ( 323) 308 54.9 2.6e-07 XP_016860391 (OMIM: 612173) PREDICTED: sperm-assoc ( 323) 308 54.9 2.6e-07 XP_016860389 (OMIM: 612173) PREDICTED: sperm-assoc ( 323) 308 54.9 2.6e-07 XP_016860387 (OMIM: 612173) PREDICTED: sperm-assoc ( 390) 308 55.0 2.9e-07 XP_016860385 (OMIM: 612173) PREDICTED: sperm-assoc ( 512) 308 55.1 3.5e-07 XP_016860386 (OMIM: 612173) PREDICTED: sperm-assoc ( 512) 308 55.1 3.5e-07 XP_011510124 (OMIM: 612173) PREDICTED: sperm-assoc ( 528) 308 55.2 3.5e-07 >>NP_006089 (OMIM: 176981) receptor of activated protein (317 aa) initn: 2171 init1: 2171 opt: 2171 Z-score: 1618.7 bits: 307.7 E(85289): 2e-83 Smith-Waterman score: 2171; 100.0% identity (100.0% similar) in 317 aa overlap (1-317:1-317) 10 20 30 40 50 60 pF1KB8 MTEQMTLRGTLKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRALR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 MTEQMTLRGTLKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRALR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 GHSHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 GHSHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQI 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 VSGSRDKTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 VSGSRDKTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLA 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 NCKLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDGGDIINALC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 NCKLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDGGDIINALC 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 FSPNRYWLCAATGPSIKIWDLEGKIIVDELKQEVISTSSKAEPPQCTSLAWSADGQTLFA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 FSPNRYWLCAATGPSIKIWDLEGKIIVDELKQEVISTSSKAEPPQCTSLAWSADGQTLFA 250 260 270 280 290 300 310 pF1KB8 GYTDNLVRVWQVTIGTR ::::::::::::::::: NP_006 GYTDNLVRVWQVTIGTR 310 >>NP_001186706 (OMIM: 614784,615973) POC1 centriolar pro (436 aa) initn: 564 init1: 159 opt: 416 Z-score: 330.0 bits: 69.7 E(85289): 1.2e-11 Smith-Waterman score: 426; 31.0% identity (60.4% similar) in 268 aa overlap (51-311:4-256) 30 40 50 60 70 pF1KB8 IATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRALR--GHSHFVSDVVISSDGQFA :. :: : ::. :..: .: :.. NP_001 MLWNFKPHARAYRYVGHKDVVTSVQFSPHGNLL 10 20 30 80 90 100 110 120 130 pF1KB8 LSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTIKLWNTLGVC :.: : :.::: .: .:: : :: ::.:.. ....:.::.::.: .. NP_001 ASASRDRTVRLWIPDKRGKFSEFKAHTAPVRSVDFSADGQFLATASEDKSIKVW-SMYRQ 40 50 60 70 80 90 140 150 160 170 180 190 pF1KB8 KYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLKTNHIGHTGYLNTV .. . :..:: :..:::.. .::::. :: .:.:. .: . .: .:. : : NP_001 RFLYSLYRHTHWVRCAKFSPDGR--LIVSCSEDKTIKIWDTTNKQCVNNFSDSVGFANFV 100 110 120 130 140 150 200 210 220 230 240 250 pF1KB8 TVSPDGSLCASGGKDGQAMLWDLNEGK---HLYTLDGGDIINALCFSPN-RYWLCAATGP .:.:. ::.:.: . .::. .: : . .:: .: . : :. : . :.. NP_001 DFNPSGTCIASAGSDQTVKVWDVRVNKLLQHYQVHSGG--VNCISFHPSGNYLITASSDG 160 170 180 190 200 260 270 280 290 300 310 pF1KB8 SIKIWDL-EGKIIVDELKQEVISTSSKAEPPQCTSLAWSADGQTLFAGYTDNLVRVWQVT ..:: :: ::..: . .... : ....: :. . .: .:. : .:. NP_001 TLKILDLLEGRLIY--------TLQGHTGP--VFTVSFSKGGELFASGGADTQVLLWRTN 210 220 230 240 250 pF1KB8 IGTR NP_001 FDELHCKGLTKRNLKRLHFDSPPHLLDIYPRTPHPHEEKVETVEINPKLEVIDLQISTPP 260 270 280 290 300 310 >>NP_002066 (OMIM: 139130,145500,617024) guanine nucleot (340 aa) initn: 333 init1: 221 opt: 405 Z-score: 323.1 bits: 68.1 E(85289): 2.9e-11 Smith-Waterman score: 405; 31.5% identity (60.0% similar) in 260 aa overlap (56-310:48-297) 30 40 50 60 70 80 pF1KB8 QFPDMILSASRDKTIIMWKLTRDETNYGIPQRALRGHSHFVSDVVISSDGQFALSGSWDG .:.:::: . . ..:... .:.: :: NP_002 IADARKACADVTLAELVSGLEVVGRVQMRTRRTLRGHLAKIYAMHWATDSKLLVSASQDG 20 30 40 50 60 70 90 100 110 120 130 140 pF1KB8 TLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTIKLWNTL---GVCKYTV : .:: : . .. . ... :.. :.. .. .. :. :. ...: : : . NP_002 KLIVWDSYTTNKVHAIPLRSSWVMTCAYAPSGNFVACGGLDNMCSIYNLKSREGNVKVSR 80 90 100 110 120 130 150 160 170 180 190 200 pF1KB8 QDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLKTNHIGHTGYLNTVTVSP . .:. ..:: :: . : :..: : : .:.. . . :: .:::: ...::: NP_002 ELSAHTGYLSCCRFLDD--NNIVTSSG-DTTCALWDIETGQQKTVFVGHTGDCMSLAVSP 140 150 160 170 180 190 210 220 230 240 250 260 pF1KB8 DGSLCASGGKDGQAMLWDLNEGKHLYTLDGGDI-INALCFSPNRYWLCAATGP-SIKIWD : .: ::. :..: :::. :: :. : . :::.:: :: .:... : ...: NP_002 DFNLFISGACDASAKLWDVREGTCRQTFTGHESDINAICFFPNGEAICTGSDDASCRLFD 200 210 220 230 240 250 270 280 290 300 310 pF1KB8 LEGKIIVDELKQEVISTSSKAEPPQCTSLAWSADGQTLFAGYTDNLVRVWQVTIGTR :.. ::.: : .. ::.:.: .:. ::::: : :: NP_002 LRA-------DQELICFSHESIICGITSVAFSLSGRLLFAGYDDFNCNVWDSMKSERVGI 260 270 280 290 300 NP_002 LSGHDNRVSCLGVTADGMAVATGSWDSFLKIWN 310 320 330 340 >>XP_011519255 (OMIM: 139130,145500,617024) PREDICTED: g (360 aa) initn: 333 init1: 221 opt: 405 Z-score: 322.8 bits: 68.1 E(85289): 3.1e-11 Smith-Waterman score: 405; 31.5% identity (60.0% similar) in 260 aa overlap (56-310:48-297) 30 40 50 60 70 80 pF1KB8 QFPDMILSASRDKTIIMWKLTRDETNYGIPQRALRGHSHFVSDVVISSDGQFALSGSWDG .:.:::: . . ..:... .:.: :: XP_011 IADARKACADVTLAELVSGLEVVGRVQMRTRRTLRGHLAKIYAMHWATDSKLLVSASQDG 20 30 40 50 60 70 90 100 110 120 130 140 pF1KB8 TLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTIKLWNTL---GVCKYTV : .:: : . .. . ... :.. :.. .. .. :. :. ...: : : . XP_011 KLIVWDSYTTNKVHAIPLRSSWVMTCAYAPSGNFVACGGLDNMCSIYNLKSREGNVKVSR 80 90 100 110 120 130 150 160 170 180 190 200 pF1KB8 QDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLKTNHIGHTGYLNTVTVSP . .:. ..:: :: . : :..: : : .:.. . . :: .:::: ...::: XP_011 ELSAHTGYLSCCRFLDD--NNIVTSSG-DTTCALWDIETGQQKTVFVGHTGDCMSLAVSP 140 150 160 170 180 190 210 220 230 240 250 260 pF1KB8 DGSLCASGGKDGQAMLWDLNEGKHLYTLDGGDI-INALCFSPNRYWLCAATGP-SIKIWD : .: ::. :..: :::. :: :. : . :::.:: :: .:... : ...: XP_011 DFNLFISGACDASAKLWDVREGTCRQTFTGHESDINAICFFPNGEAICTGSDDASCRLFD 200 210 220 230 240 250 270 280 290 300 310 pF1KB8 LEGKIIVDELKQEVISTSSKAEPPQCTSLAWSADGQTLFAGYTDNLVRVWQVTIGTR :.. ::.: : .. ::.:.: .:. ::::: : :: XP_011 LRA-------DQELICFSHESIICGITSVAFSLSGRLLFAGYDDFNCNVWDSMKSERVGK 260 270 280 290 300 XP_011 GQPWLLLPQLEGPSPALPPHSVPPISSHFGLSYCCPLSLGDSTPGIQYPLVPN 310 320 330 340 350 360 >>XP_016861593 (OMIM: 614783,614813) PREDICTED: POC1 cen (321 aa) initn: 465 init1: 173 opt: 392 Z-score: 313.8 bits: 66.3 E(85289): 9.7e-11 Smith-Waterman score: 418; 31.6% identity (59.2% similar) in 282 aa overlap (37-311:2-261) 10 20 30 40 50 60 pF1KB8 LRGTLKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQ-RALR--GHS :. ...:.. :: :: : ::. XP_016 MDSCLMVWHMK--------PQSRAYRFTGHK 10 20 70 80 90 100 110 120 pF1KB8 HFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSG :. : .: .:.. ::: : :.:.: .. . : .:: : :: : ::....:.. XP_016 DAVTCVNFSPSGHLLASGSRDKTVRIWVPNVKGESTVFRAHTATVRSVHFCSDGQSFVTA 30 40 50 60 70 80 130 140 150 160 170 180 pF1KB8 SRDKTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCK : :::.:.: : :. . .: .:: :..:::.. .::: . :: ::.:. .. . XP_016 SDDKTVKVWAT-HRQKFLFSLSQHINWVRCAKFSPDGR--LIVSASDDKTVKLWDKSSRE 90 100 110 120 130 140 190 200 210 220 230 240 pF1KB8 LKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHL--YTLDGGDIINALCF .. : :... : :.:. :..: :. . .::. . : : : .. .:.: : XP_016 CVHSYCEHGGFVTYVDFHPSGTCIAAAGMDNTVKVWDVRTHRLLQHYQLHSA-AVNGLSF 150 160 170 180 190 250 260 270 280 290 pF1KB8 SPN-RYWLCAATGPSIKIWDL-EGKIIVDELKQEVISTSSKAEPPQCTSLAWSADGQTLF :. : . :.. ..:: :: ::... : . : :..:.: :. . XP_016 HPSGNYLITASSDSTLKILDLMEGRLLY---------TLHGHQGPA-TTVAFSRTGEYFA 200 210 220 230 240 300 310 pF1KB8 AGYTDNLVRVWQVTIGTR .: .:. : ::. XP_016 SGGSDEQVMVWKSNFDIVDHGEVTKVPRPPATLASSMGNLTVSILEQRLTLTEDKLKQCL 250 260 270 280 290 300 >>NP_001155053 (OMIM: 614783,614813) POC1 centriolar pro (369 aa) initn: 465 init1: 173 opt: 392 Z-score: 313.1 bits: 66.4 E(85289): 1.1e-10 Smith-Waterman score: 418; 31.6% identity (59.2% similar) in 282 aa overlap (37-311:2-261) 10 20 30 40 50 60 pF1KB8 LRGTLKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQ-RALR--GHS :. ...:.. :: :: : ::. NP_001 MDSCLMVWHMK--------PQSRAYRFTGHK 10 20 70 80 90 100 110 120 pF1KB8 HFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSG :. : .: .:.. ::: : :.:.: .. . : .:: : :: : ::....:.. NP_001 DAVTCVNFSPSGHLLASGSRDKTVRIWVPNVKGESTVFRAHTATVRSVHFCSDGQSFVTA 30 40 50 60 70 80 130 140 150 160 170 180 pF1KB8 SRDKTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCK : :::.:.: : :. . .: .:: :..:::.. .::: . :: ::.:. .. . NP_001 SDDKTVKVWAT-HRQKFLFSLSQHINWVRCAKFSPDGR--LIVSASDDKTVKLWDKSSRE 90 100 110 120 130 140 190 200 210 220 230 240 pF1KB8 LKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHL--YTLDGGDIINALCF .. : :... : :.:. :..: :. . .::. . : : : .. .:.: : NP_001 CVHSYCEHGGFVTYVDFHPSGTCIAAAGMDNTVKVWDVRTHRLLQHYQLHSA-AVNGLSF 150 160 170 180 190 250 260 270 280 290 pF1KB8 SPN-RYWLCAATGPSIKIWDL-EGKIIVDELKQEVISTSSKAEPPQCTSLAWSADGQTLF :. : . :.. ..:: :: ::... : . : :..:.: :. . NP_001 HPSGNYLITASSDSTLKILDLMEGRLLY---------TLHGHQGPA-TTVAFSRTGEYFA 200 210 220 230 240 300 310 pF1KB8 AGYTDNLVRVWQVTIGTR .: .:. : ::. NP_001 SGGSDEQVMVWKSNFDIVDHGEVTKVPRPPATLASSMGNLPEVDFPVPPGRGRSVESVQS 250 260 270 280 290 300 >>XP_016880191 (OMIM: 601545,607432) PREDICTED: platelet (345 aa) initn: 557 init1: 203 opt: 388 Z-score: 310.5 bits: 65.8 E(85289): 1.5e-10 Smith-Waterman score: 461; 31.2% identity (56.8% similar) in 324 aa overlap (11-311:39-343) 10 20 30 40 pF1KB8 MTEQMTLRGTLKGHNGWVTQIATTPQFPDMILSASRDKTI :.:: . ::.. : : :. :::.: :: XP_016 EAKEEFTSGGPLGQKRDPKEWIPRPPEKYALSGHRSPVTRVIFHPVFSVMV-SASEDATI 10 20 30 40 50 60 50 60 70 80 90 100 pF1KB8 IMWKLTRDETNYGIPQRALRGHSHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRR .: :: : .:.:.::. :.:. .. .:.. : : : :..:::. : XP_016 KVWDY---ET--GDFERTLKGHTDSVQDISFDHSGKLLASCSADMTIKLWDFQGFECIRT 70 80 90 100 110 120 110 120 130 140 150 pF1KB8 FVGHTKDVLSVAFSSDNRQIVSGSRDKTIKLWNT-LGVCKYTVQDESHSEWVSCVRFSPN . :: ..: :::. .. .:::.:::::::.:.. : : : .: ::: :: :: XP_016 MHGHDHNVSSVAIMPNGDHIVSASRDKTIKMWEVQTGYCVKTFT--GHREWVRMVR--PN 130 140 150 160 170 160 170 180 190 200 pF1KB8 SSNPIIVSCGWDKLVKVWNLANCKLKTNHIGHTGYLNTVTVSPDGSLCA----------- ... .:.::. :. :.:: .:. . :.. : .. .. .:..: . XP_016 QDGTLIASCSNDQTVRVWVVATKECKAELREHEHVVECISWAPESSYSSISEATGSETKK 180 190 200 210 220 230 210 220 230 240 250 pF1KB8 ---------SGGKDGQAMLWDLNEGKHLYTLDGGD--IINALCFSPNRYWLCAATGPSIK ::..: .::.. : :.:: : : . ..: : ... : : ... XP_016 SGKPGPFLLSGSRDKTIKMWDVSTGMCLMTLVGHDNWVRGVLFHSGGKFILSCADDKTLR 240 250 260 270 280 290 260 270 280 290 300 310 pF1KB8 IWDLEGKIIVDELKQEVISTSSKAEPPQCTSLAWSADGQTLFAGYTDNLVRVWQVTIGTR .:: ..: . :. :. ::: . . . .: .:. :.::. XP_016 VWDYKNKRCMKTLN---------AHEHFVTSLDFHKTAPYVVTGSVDQTVKVWECR 300 310 320 330 340 >>XP_016880188 (OMIM: 601545,607432) PREDICTED: platelet (410 aa) initn: 557 init1: 203 opt: 388 Z-score: 309.7 bits: 65.9 E(85289): 1.6e-10 Smith-Waterman score: 461; 31.2% identity (56.8% similar) in 324 aa overlap (11-311:104-408) 10 20 30 40 pF1KB8 MTEQMTLRGTLKGHNGWVTQIATTPQFPDMILSASRDKTI :.:: . ::.. : : :. :::.: :: XP_016 EAKEEFTSGGPLGQKRDPKEWIPRPPEKYALSGHRSPVTRVIFHPVFSVMV-SASEDATI 80 90 100 110 120 130 50 60 70 80 90 100 pF1KB8 IMWKLTRDETNYGIPQRALRGHSHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRR .: :: : .:.:.::. :.:. .. .:.. : : : :..:::. : XP_016 KVWDY---ET--GDFERTLKGHTDSVQDISFDHSGKLLASCSADMTIKLWDFQGFECIRT 140 150 160 170 180 110 120 130 140 150 pF1KB8 FVGHTKDVLSVAFSSDNRQIVSGSRDKTIKLWNT-LGVCKYTVQDESHSEWVSCVRFSPN . :: ..: :::. .. .:::.:::::::.:.. : : : .: ::: :: :: XP_016 MHGHDHNVSSVAIMPNGDHIVSASRDKTIKMWEVQTGYCVKTFT--GHREWVRMVR--PN 190 200 210 220 230 240 160 170 180 190 200 pF1KB8 SSNPIIVSCGWDKLVKVWNLANCKLKTNHIGHTGYLNTVTVSPDGSLCA----------- ... .:.::. :. :.:: .:. . :.. : .. .. .:..: . XP_016 QDGTLIASCSNDQTVRVWVVATKECKAELREHEHVVECISWAPESSYSSISEATGSETKK 250 260 270 280 290 300 210 220 230 240 250 pF1KB8 ---------SGGKDGQAMLWDLNEGKHLYTLDGGD--IINALCFSPNRYWLCAATGPSIK ::..: .::.. : :.:: : : . ..: : ... : : ... XP_016 SGKPGPFLLSGSRDKTIKMWDVSTGMCLMTLVGHDNWVRGVLFHSGGKFILSCADDKTLR 310 320 330 340 350 360 260 270 280 290 300 310 pF1KB8 IWDLEGKIIVDELKQEVISTSSKAEPPQCTSLAWSADGQTLFAGYTDNLVRVWQVTIGTR .:: ..: . :. :. ::: . . . .: .:. :.::. XP_016 VWDYKNKRCMKTLN---------AHEHFVTSLDFHKTAPYVVTGSVDQTVKVWECR 370 380 390 400 410 >>XP_016880189 (OMIM: 601545,607432) PREDICTED: platelet (410 aa) initn: 557 init1: 203 opt: 388 Z-score: 309.7 bits: 65.9 E(85289): 1.6e-10 Smith-Waterman score: 461; 31.2% identity (56.8% similar) in 324 aa overlap (11-311:104-408) 10 20 30 40 pF1KB8 MTEQMTLRGTLKGHNGWVTQIATTPQFPDMILSASRDKTI :.:: . ::.. : : :. :::.: :: XP_016 EAKEEFTSGGPLGQKRDPKEWIPRPPEKYALSGHRSPVTRVIFHPVFSVMV-SASEDATI 80 90 100 110 120 130 50 60 70 80 90 100 pF1KB8 IMWKLTRDETNYGIPQRALRGHSHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRR .: :: : .:.:.::. :.:. .. .:.. : : : :..:::. : XP_016 KVWDY---ET--GDFERTLKGHTDSVQDISFDHSGKLLASCSADMTIKLWDFQGFECIRT 140 150 160 170 180 110 120 130 140 150 pF1KB8 FVGHTKDVLSVAFSSDNRQIVSGSRDKTIKLWNT-LGVCKYTVQDESHSEWVSCVRFSPN . :: ..: :::. .. .:::.:::::::.:.. : : : .: ::: :: :: XP_016 MHGHDHNVSSVAIMPNGDHIVSASRDKTIKMWEVQTGYCVKTFT--GHREWVRMVR--PN 190 200 210 220 230 240 160 170 180 190 200 pF1KB8 SSNPIIVSCGWDKLVKVWNLANCKLKTNHIGHTGYLNTVTVSPDGSLCA----------- ... .:.::. :. :.:: .:. . :.. : .. .. .:..: . XP_016 QDGTLIASCSNDQTVRVWVVATKECKAELREHEHVVECISWAPESSYSSISEATGSETKK 250 260 270 280 290 300 210 220 230 240 250 pF1KB8 ---------SGGKDGQAMLWDLNEGKHLYTLDGGD--IINALCFSPNRYWLCAATGPSIK ::..: .::.. : :.:: : : . ..: : ... : : ... XP_016 SGKPGPFLLSGSRDKTIKMWDVSTGMCLMTLVGHDNWVRGVLFHSGGKFILSCADDKTLR 310 320 330 340 350 360 260 270 280 290 300 310 pF1KB8 IWDLEGKIIVDELKQEVISTSSKAEPPQCTSLAWSADGQTLFAGYTDNLVRVWQVTIGTR .:: ..: . :. :. ::: . . . .: .:. :.::. XP_016 VWDYKNKRCMKTLN---------AHEHFVTSLDFHKTAPYVVTGSVDQTVKVWECR 370 380 390 400 410 >>NP_000421 (OMIM: 601545,607432) platelet-activating fa (410 aa) initn: 557 init1: 203 opt: 388 Z-score: 309.7 bits: 65.9 E(85289): 1.6e-10 Smith-Waterman score: 461; 31.2% identity (56.8% similar) in 324 aa overlap (11-311:104-408) 10 20 30 40 pF1KB8 MTEQMTLRGTLKGHNGWVTQIATTPQFPDMILSASRDKTI :.:: . ::.. : : :. :::.: :: NP_000 EAKEEFTSGGPLGQKRDPKEWIPRPPEKYALSGHRSPVTRVIFHPVFSVMV-SASEDATI 80 90 100 110 120 130 50 60 70 80 90 100 pF1KB8 IMWKLTRDETNYGIPQRALRGHSHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRR .: :: : .:.:.::. :.:. .. .:.. : : : :..:::. : NP_000 KVWDY---ET--GDFERTLKGHTDSVQDISFDHSGKLLASCSADMTIKLWDFQGFECIRT 140 150 160 170 180 110 120 130 140 150 pF1KB8 FVGHTKDVLSVAFSSDNRQIVSGSRDKTIKLWNT-LGVCKYTVQDESHSEWVSCVRFSPN . :: ..: :::. .. .:::.:::::::.:.. : : : .: ::: :: :: NP_000 MHGHDHNVSSVAIMPNGDHIVSASRDKTIKMWEVQTGYCVKTFT--GHREWVRMVR--PN 190 200 210 220 230 240 160 170 180 190 200 pF1KB8 SSNPIIVSCGWDKLVKVWNLANCKLKTNHIGHTGYLNTVTVSPDGSLCA----------- ... .:.::. :. :.:: .:. . :.. : .. .. .:..: . NP_000 QDGTLIASCSNDQTVRVWVVATKECKAELREHEHVVECISWAPESSYSSISEATGSETKK 250 260 270 280 290 300 210 220 230 240 250 pF1KB8 ---------SGGKDGQAMLWDLNEGKHLYTLDGGD--IINALCFSPNRYWLCAATGPSIK ::..: .::.. : :.:: : : . ..: : ... : : ... NP_000 SGKPGPFLLSGSRDKTIKMWDVSTGMCLMTLVGHDNWVRGVLFHSGGKFILSCADDKTLR 310 320 330 340 350 360 260 270 280 290 300 310 pF1KB8 IWDLEGKIIVDELKQEVISTSSKAEPPQCTSLAWSADGQTLFAGYTDNLVRVWQVTIGTR .:: ..: . :. :. ::: . . . .: .:. :.::. NP_000 VWDYKNKRCMKTLN---------AHEHFVTSLDFHKTAPYVVTGSVDQTVKVWECR 370 380 390 400 410 317 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 11:04:14 2016 done: Fri Nov 4 11:04:15 2016 Total Scan time: 5.680 Total Display time: 0.030 Function used was FASTA [36.3.4 Apr, 2011]