Result of FASTA (omim) for
pF1KB8262
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB8262, 191 aa
1>>>pF1KB8262 191 - 191 aa - 191 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.5491+/-0.000389; mu= 12.6936+/- 0.024
mean_var=95.1791+/-18.646, 0's: 0 Z-trim(114.9): 150 B-trim: 177 in 1/51
Lambda= 0.131463
statistics sampled from 24899 (25071) to 24899 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.679), E-opt: 0.2 (0.294), width: 16
Scan time: 4.750
The best scores are: opt bits E(85289)
NP_006375 (OMIM: 602293) calcium and integrin-bind ( 191) 1230 243.1 2.1e-64
XP_006720438 (OMIM: 602293) PREDICTED: calcium and ( 264) 1191 235.8 4.4e-62
NP_001264693 (OMIM: 602293) calcium and integrin-b ( 231) 1063 211.5 8.1e-55
NP_001025052 (OMIM: 610646) calcium and integrin-b ( 185) 489 102.6 4.1e-22
XP_011530816 (OMIM: 610646) PREDICTED: calcium and ( 201) 469 98.8 6e-21
NP_473454 (OMIM: 610645) calcium and integrin-bind ( 187) 458 96.7 2.4e-20
NP_006374 (OMIM: 605564,609439,614869) calcium and ( 187) 447 94.6 1e-19
XP_005254183 (OMIM: 605564,609439,614869) PREDICTE ( 210) 429 91.2 1.2e-18
XP_016858818 (OMIM: 610646) PREDICTED: calcium and ( 162) 420 89.4 3.2e-18
XP_011530819 (OMIM: 610646) PREDICTED: calcium and ( 187) 384 82.6 4e-16
XP_016858819 (OMIM: 610646) PREDICTED: calcium and ( 140) 382 82.1 4.3e-16
NP_001288153 (OMIM: 605564,609439,614869) calcium ( 192) 374 80.8 1.5e-15
NP_001258817 (OMIM: 605564,609439,614869) calcium ( 144) 357 77.4 1.2e-14
XP_006720437 (OMIM: 605564,609439,614869) PREDICTE ( 144) 357 77.4 1.2e-14
XP_011519463 (OMIM: 605564,609439,614869) PREDICTE ( 167) 339 74.1 1.4e-13
NP_001287851 (OMIM: 610645) calcium and integrin-b ( 138) 323 71.0 9.8e-13
NP_001258818 (OMIM: 605564,609439,614869) calcium ( 138) 315 69.4 2.8e-12
NP_000936 (OMIM: 601302) calcineurin subunit B typ ( 170) 240 55.3 6.3e-08
NP_671709 (OMIM: 613821) calcineurin subunit B typ ( 173) 217 50.9 1.3e-06
NP_055101 (OMIM: 603315) neuronal calcium sensor 1 ( 190) 209 49.5 4e-06
NP_775285 (OMIM: 604661) Kv channel-interacting pr ( 227) 186 45.2 9.4e-05
NP_775287 (OMIM: 604661) Kv channel-interacting pr ( 220) 185 45.0 0.0001
NP_775286 (OMIM: 604661) Kv channel-interacting pr ( 225) 185 45.0 0.00011
NP_001265269 (OMIM: 604660) Kv channel-interacting ( 188) 184 44.7 0.00011
XP_016871650 (OMIM: 604661) PREDICTED: Kv channel- ( 230) 185 45.0 0.00011
NP_775284 (OMIM: 604661) Kv channel-interacting pr ( 252) 185 45.0 0.00012
NP_055407 (OMIM: 604660) Kv channel-interacting pr ( 216) 184 44.8 0.00012
XP_016864896 (OMIM: 604660) PREDICTED: Kv channel- ( 225) 184 44.8 0.00012
NP_001030010 (OMIM: 604660) Kv channel-interacting ( 225) 184 44.8 0.00012
NP_775283 (OMIM: 604661) Kv channel-interacting pr ( 270) 185 45.0 0.00012
NP_001030009 (OMIM: 604660) Kv channel-interacting ( 227) 184 44.8 0.00012
NP_055406 (OMIM: 604661) Kv channel-interacting pr ( 285) 185 45.1 0.00013
NP_003376 (OMIM: 600817) visinin-like protein 1 [H ( 191) 181 44.1 0.00016
XP_005269787 (OMIM: 604661) PREDICTED: Kv channel- ( 225) 181 44.2 0.00018
XP_011538033 (OMIM: 604661) PREDICTED: Kv channel- ( 230) 181 44.2 0.00018
XP_005269786 (OMIM: 604661) PREDICTED: Kv channel- ( 257) 181 44.3 0.0002
XP_006717875 (OMIM: 604661) PREDICTED: Kv channel- ( 275) 181 44.3 0.00021
NP_671711 (OMIM: 608182) Kv channel-interacting pr ( 188) 170 42.1 0.00067
XP_016864142 (OMIM: 608182) PREDICTED: Kv channel- ( 188) 170 42.1 0.00067
NP_001030176 (OMIM: 608182) Kv channel-interacting ( 188) 170 42.1 0.00067
NP_671710 (OMIM: 608182) Kv channel-interacting pr ( 216) 170 42.1 0.00074
NP_001030175 (OMIM: 608182) Kv channel-interacting ( 225) 170 42.1 0.00076
NP_671712 (OMIM: 608182) Kv channel-interacting pr ( 229) 170 42.1 0.00077
XP_005248247 (OMIM: 608182) PREDICTED: Kv channel- ( 233) 170 42.1 0.00078
NP_079497 (OMIM: 608182) Kv channel-interacting pr ( 250) 170 42.2 0.00083
NP_001122298 (OMIM: 603315) neuronal calcium senso ( 172) 166 41.3 0.0011
NP_001074214 (OMIM: 601854) diacylglycerol kinase ( 752) 174 43.4 0.0011
NP_001074213 (OMIM: 601854) diacylglycerol kinase ( 766) 174 43.4 0.0011
NP_001337 (OMIM: 601854) diacylglycerol kinase gam ( 791) 174 43.4 0.0011
XP_011512191 (OMIM: 608182) PREDICTED: Kv channel- ( 195) 166 41.3 0.0012
>>NP_006375 (OMIM: 602293) calcium and integrin-binding (191 aa)
initn: 1230 init1: 1230 opt: 1230 Z-score: 1277.4 bits: 243.1 E(85289): 2.1e-64
Smith-Waterman score: 1230; 100.0% identity (100.0% similar) in 191 aa overlap (1-191:1-191)
10 20 30 40 50 60
pF1KB8 MGGSGSRLSKELLAEYQDLTFLTKQEILLAHRRFCELLPQEQRSVESSLRAQVPFEQILS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 MGGSGSRLSKELLAEYQDLTFLTKQEILLAHRRFCELLPQEQRSVESSLRAQVPFEQILS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 LPELKANPFKERICRVFSTSPAKDSLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDDD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 LPELKANPFKERICRVFSTSPAKDSLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDDD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 GTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINLSEFQHVISRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 GTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINLSEFQHVISRS
130 140 150 160 170 180
190
pF1KB8 PDFASSFKIVL
:::::::::::
NP_006 PDFASSFKIVL
190
>>XP_006720438 (OMIM: 602293) PREDICTED: calcium and int (264 aa)
initn: 1191 init1: 1191 opt: 1191 Z-score: 1235.6 bits: 235.8 E(85289): 4.4e-62
Smith-Waterman score: 1191; 100.0% identity (100.0% similar) in 184 aa overlap (1-184:1-184)
10 20 30 40 50 60
pF1KB8 MGGSGSRLSKELLAEYQDLTFLTKQEILLAHRRFCELLPQEQRSVESSLRAQVPFEQILS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MGGSGSRLSKELLAEYQDLTFLTKQEILLAHRRFCELLPQEQRSVESSLRAQVPFEQILS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 LPELKANPFKERICRVFSTSPAKDSLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDDD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LPELKANPFKERICRVFSTSPAKDSLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDDD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 GTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINLSEFQHVISRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINLSEFQHVISRS
130 140 150 160 170 180
190
pF1KB8 PDFASSFKIVL
::::
XP_006 PDFARYDSGPPSFWVPAGSDLLPLGLGHGYRRWCQGERKPQSPHTGPAKLAVSPRAGAAL
190 200 210 220 230 240
>>NP_001264693 (OMIM: 602293) calcium and integrin-bindi (231 aa)
initn: 1217 init1: 1054 opt: 1063 Z-score: 1105.2 bits: 211.5 E(85289): 8.1e-55
Smith-Waterman score: 1087; 82.1% identity (82.1% similar) in 223 aa overlap (9-191:9-231)
10 20
pF1KB8 MGGSGSRLSKELLAEYQDLTFLTKQEILL-------------------------------
:::::::::::::::::::::
NP_001 MGGSGSRLSKELLAEYQDLTFLTKQEILLSVYVVLAPHLVDNEQQARSGNEHTGRPIAEN
10 20 30 40 50 60
30 40 50 60 70 80
pF1KB8 ---------AHRRFCELLPQEQRSVESSLRAQVPFEQILSLPELKANPFKERICRVFSTS
:::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TDSSPLSTRAHRRFCELLPQEQRSVESSLRAQVPFEQILSLPELKANPFKERICRVFSTS
70 80 90 100 110 120
90 100 110 120 130 140
pF1KB8 PAKDSLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDDDGTLNREDLSRLVNCLTGEGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PAKDSLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDDDGTLNREDLSRLVNCLTGEGE
130 140 150 160 170 180
150 160 170 180 190
pF1KB8 DTRLSASEMKQLIDNILEESDIDRDGTINLSEFQHVISRSPDFASSFKIVL
:::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DTRLSASEMKQLIDNILEESDIDRDGTINLSEFQHVISRSPDFASSFKIVL
190 200 210 220 230
>>NP_001025052 (OMIM: 610646) calcium and integrin-bindi (185 aa)
initn: 489 init1: 175 opt: 489 Z-score: 518.1 bits: 102.6 E(85289): 4.1e-22
Smith-Waterman score: 489; 44.7% identity (73.2% similar) in 179 aa overlap (11-189:12-180)
10 20 30 40 50
pF1KB8 MGGSGSRLSKELLAEYQDLTFLTKQEILLAHRRFCELLPQEQRSVESSLRAQVPFEQIL
: : ::: :::::..::: : : .: : . :..: ..:.
NP_001 MGQCLRYQMHWEDLEEYQALTFLTRNEILCIHDTFLKLCPPGKYYKEATLT----MDQVS
10 20 30 40 50
60 70 80 90 100 110
pF1KB8 SLPELKANPFKERICRVFSTSPAKDSLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDD
::: :..:::..::::::: : .:::: : . ::::. : :..: .:::::.::..
NP_001 SLPALRVNPFRDRICRVFS---HKGMFSFEDVLGMASVFSEQACPSLKIEYAFRIYDFNE
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB8 DGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINLSEFQHVISR
.: ...:::.:.. : . ..: .: . . .: ...: :::.: :. ...:::.:....
NP_001 NGFIDEEDLQRIILRLLN-SDD--MSEDLLMDLTNHVLSESDLDNDNMLSFSEFEHAMAK
120 130 140 150 160 170
180 190
pF1KB8 SPDFASSFKIVL
:::: .::.:
NP_001 SPDFMNSFRIHFWGC
180
>>XP_011530816 (OMIM: 610646) PREDICTED: calcium and int (201 aa)
initn: 470 init1: 175 opt: 469 Z-score: 497.1 bits: 98.8 E(85289): 6e-21
Smith-Waterman score: 477; 42.9% identity (71.4% similar) in 189 aa overlap (1-189:21-196)
10 20 30 40
pF1KB8 MGGSGSRLSKELLAEYQDLTFLTKQEILLAHRRFCELLPQ
:.: . : .:: : :::::..::: : : .: :
XP_011 MLEVSDALGGPGRVPGATAGMNGVDTSLLCDLL---QALTFLTRNEILCIHDTFLKLCPP
10 20 30 40 50
50 60 70 80 90 100
pF1KB8 EQRSVESSLRAQVPFEQILSLPELKANPFKERICRVFSTSPAKDSLSFEDFLDLLSVFSD
. :..: ..:. ::: :..:::..::::::: : .:::: : . ::::.
XP_011 GKYYKEATLT----MDQVSSLPALRVNPFRDRICRVFSH---KGMFSFEDVLGMASVFSE
60 70 80 90 100 110
110 120 130 140 150 160
pF1KB8 TATPDIKSHYAFRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEES
: :..: .:::::.::...: ...:::.:.. : . ..: .: . . .: ...: ::
XP_011 QACPSLKIEYAFRIYDFNENGFIDEEDLQRIILRLLN-SDD--MSEDLLMDLTNHVLSES
120 130 140 150 160
170 180 190
pF1KB8 DIDRDGTINLSEFQHVISRSPDFASSFKIVL
:.: :. ...:::.:....:::: .::.:
XP_011 DLDNDNMLSFSEFEHAMAKSPDFMNSFRIHFWGC
170 180 190 200
>>NP_473454 (OMIM: 610645) calcium and integrin-binding (187 aa)
initn: 314 init1: 183 opt: 458 Z-score: 486.2 bits: 96.7 E(85289): 2.4e-20
Smith-Waterman score: 458; 40.0% identity (71.1% similar) in 190 aa overlap (1-189:1-185)
10 20 30 40 50
pF1KB8 MGGSGSRLSKELLAEYQDLTFLTKQEILLAHRRFCELLPQE-QRSVESSLRAQVPFEQIL
::.. . ...: : ::: ::.:..::. :. .: :: . . ..::.: :
NP_473 MGNKQTVFTHEQLEAYQDCTFFTRKEIMRLFYRYQDLAPQLVPLDYTTCPDVKVPYELIG
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB8 SLPELKANPFKERICRVFSTSPAKDSLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDD
:.:::: :::..:: .::: . . .....:::..::.:. : :.:..:::.:.::..
NP_473 SMPELKDNPFRQRIAQVFSED-GDGHMTLDNFLDMFSVMSEMAPRDLKAYYAFKIYDFNN
70 80 90 100 110
120 130 140 150 160 170
pF1KB8 DGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINLSEFQHVISR
: . :: . :. :: : ::: :.. . ...:.:.: :.:: ..: .::..: :
NP_473 DDYICAWDLEQTVTKLTRGG----LSAEEVSLVCEKVLDEADGDHDGRLSLEDFQNMILR
120 130 140 150 160 170
180 190
pF1KB8 SPDFASSFKIVL
.::: :.:.:
NP_473 APDFLSTFHIRI
180
>>NP_006374 (OMIM: 605564,609439,614869) calcium and int (187 aa)
initn: 284 init1: 185 opt: 447 Z-score: 475.0 bits: 94.6 E(85289): 1e-19
Smith-Waterman score: 447; 37.9% identity (73.7% similar) in 190 aa overlap (1-189:1-185)
10 20 30 40 50
pF1KB8 MGGSGSRLSKELLAEYQDLTFLTKQEILLAHRRFCELLPQE-QRSVESSLRAQVPFEQIL
::.. . ...: : .::: ::..:..:: : :: :: :. . ..: ..::. :.
NP_006 MGNKQTIFTEEQLDNYQDCTFFNKKDILKLHSRFYELAPNLVPMDYRKSPIVHVPMSLII
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB8 SLPELKANPFKERICRVFSTSPAKDSLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDD
..:::. ::::::: .:: . .. .:.:.::.:..::. ..: ..:..:::.:.::.
NP_006 QMPELRENPFKERIVAAFSED-GEGNLTFNDFVDMFSVLCESAPRELKANYAFKIYDFNT
70 80 90 100 110
120 130 140 150 160 170
pF1KB8 DGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINLSEFQHVISR
:. . .::: . :: ..:. :. . :...::.:.: :: .....:. .:..
NP_006 DNFICKEDLELTLARLT----KSELDEEEVVLVCDKVIEEADLDGDGKLGFADFEDMIAK
120 130 140 150 160 170
180 190
pF1KB8 SPDFASSFKIVL
.::: :.:.:
NP_006 APDFLSTFHIRI
180
>>XP_005254183 (OMIM: 605564,609439,614869) PREDICTED: c (210 aa)
initn: 280 init1: 185 opt: 429 Z-score: 455.9 bits: 91.2 E(85289): 1.2e-18
Smith-Waterman score: 429; 37.5% identity (73.4% similar) in 184 aa overlap (1-183:1-179)
10 20 30 40 50
pF1KB8 MGGSGSRLSKELLAEYQDLTFLTKQEILLAHRRFCELLPQE-QRSVESSLRAQVPFEQIL
::.. . ...: : .::: ::..:..:: : :: :: :. . ..: ..::. :.
XP_005 MGNKQTIFTEEQLDNYQDCTFFNKKDILKLHSRFYELAPNLVPMDYRKSPIVHVPMSLII
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB8 SLPELKANPFKERICRVFSTSPAKDSLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDD
..:::. ::::::: .:: . .. .:.:.::.:..::. ..: ..:..:::.:.::.
XP_005 QMPELRENPFKERIVAAFSED-GEGNLTFNDFVDMFSVLCESAPRELKANYAFKIYDFNT
70 80 90 100 110
120 130 140 150 160 170
pF1KB8 DGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINLSEFQHVISR
:. . .::: . :: ..:. :. . :...::.:.: :: .....:. .:..
XP_005 DNFICKEDLELTLARLT----KSELDEEEVVLVCDKVIEEADLDGDGKLGFADFEDMIAK
120 130 140 150 160 170
180 190
pF1KB8 SPDFASSFKIVL
.:::
XP_005 APDFLRCCHYRGRAWAGQSRAGRDVGAEAPITRYL
180 190 200 210
>>XP_016858818 (OMIM: 610646) PREDICTED: calcium and int (162 aa)
initn: 413 init1: 175 opt: 420 Z-score: 448.1 bits: 89.4 E(85289): 3.2e-18
Smith-Waterman score: 420; 42.1% identity (73.0% similar) in 159 aa overlap (31-189:9-157)
10 20 30 40 50 60
pF1KB8 MGGSGSRLSKELLAEYQDLTFLTKQEILLAHRRFCELLPQEQRSVESSLRAQVPFEQILS
: : .: : . :..: ..:. :
XP_016 MKRTQVNIHDTFLKLCPPGKYYKEATLT----MDQVSS
10 20 30
70 80 90 100 110 120
pF1KB8 LPELKANPFKERICRVFSTSPAKDSLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDDD
:: :..:::..::::::: : .:::: : . ::::. : :..: .:::::.::...
XP_016 LPALRVNPFRDRICRVFSH---KGMFSFEDVLGMASVFSEQACPSLKIEYAFRIYDFNEN
40 50 60 70 80 90
130 140 150 160 170 180
pF1KB8 GTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINLSEFQHVISRS
: ...:::.:.. : . ..: .: . . .: ...: :::.: :. ...:::.:....:
XP_016 GFIDEEDLQRIILRLLN-SDD--MSEDLLMDLTNHVLSESDLDNDNMLSFSEFEHAMAKS
100 110 120 130 140
190
pF1KB8 PDFASSFKIVL
::: .::.:
XP_016 PDFMNSFRIHFWGC
150 160
>>XP_011530819 (OMIM: 610646) PREDICTED: calcium and int (187 aa)
initn: 383 init1: 175 opt: 384 Z-score: 410.4 bits: 82.6 E(85289): 4e-16
Smith-Waterman score: 384; 42.2% identity (71.4% similar) in 161 aa overlap (35-189:28-182)
10 20 30 40 50
pF1KB8 GSRLSKELLAEYQDLTFLTKQEILLAHRRFC-ELLP--QEQRSVES--SLRAQVPFEQIL
: ::.: :: . .: :.:. :
XP_011 MVRMAPKVSAPSRFLCISQSFPSLSESCLELVPICLEQLAKNSLPRLKAMKSPEIYS
10 20 30 40 50
60 70 80 90 100 110
pF1KB8 SLPE-LKANPFKERICRVFSTSPAKDSLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFD
.. : ::.:::..::::::: : .:::: : . ::::. : :..: .:::::.::.
XP_011 AFQEILKVNPFRDRICRVFS---HKGMFSFEDVLGMASVFSEQACPSLKIEYAFRIYDFN
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB8 DDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINLSEFQHVIS
..: ...:::.:.. : . . .: . . .: ...: :::.: :. ...:::.:...
XP_011 ENGFIDEEDLQRIILRLLNSDD---MSEDLLMDLTNHVLSESDLDNDNMLSFSEFEHAMA
120 130 140 150 160 170
180 190
pF1KB8 RSPDFASSFKIVL
.:::: .::.:
XP_011 KSPDFMNSFRIHFWGC
180
191 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 11:07:47 2016 done: Fri Nov 4 11:07:48 2016
Total Scan time: 4.750 Total Display time: 0.010
Function used was FASTA [36.3.4 Apr, 2011]