FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB8264, 210 aa 1>>>pF1KB8264 210 - 210 aa - 210 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.3594+/-0.000359; mu= 13.8938+/- 0.022 mean_var=70.9056+/-13.868, 0's: 0 Z-trim(113.3): 17 B-trim: 42 in 1/57 Lambda= 0.152312 statistics sampled from 22598 (22614) to 22598 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.656), E-opt: 0.2 (0.265), width: 16 Scan time: 4.090 The best scores are: opt bits E(85289) NP_002686 (OMIM: 180664) DNA-directed RNA polymera ( 210) 1381 312.3 3.7e-85 XP_011526372 (OMIM: 180664) PREDICTED: DNA-directe ( 211) 1358 307.2 1.2e-83 NP_001303252 (OMIM: 180664) DNA-directed RNA polym ( 117) 739 171.1 6.7e-43 NP_001303253 (OMIM: 180664) DNA-directed RNA polym ( 117) 739 171.1 6.7e-43 XP_016882372 (OMIM: 180664) PREDICTED: DNA-directe ( 118) 727 168.4 4.2e-42 >>NP_002686 (OMIM: 180664) DNA-directed RNA polymerases (210 aa) initn: 1381 init1: 1381 opt: 1381 Z-score: 1649.9 bits: 312.3 E(85289): 3.7e-85 Smith-Waterman score: 1381; 100.0% identity (100.0% similar) in 210 aa overlap (1-210:1-210) 10 20 30 40 50 60 pF1KB8 MDDEEETYRLWKIRKTIMQLCHDRGYLVTQDELDQTLEEFKAQFGDKPSEGRPRRTDLTV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 MDDEEETYRLWKIRKTIMQLCHDRGYLVTQDELDQTLEEFKAQFGDKPSEGRPRRTDLTV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 LVAHNDDPTDQMFVFFPEEPKVGIKTIKVYCQRMQEENITRALIVVQQGMTPSAKQSLVD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 LVAHNDDPTDQMFVFFPEEPKVGIKTIKVYCQRMQEENITRALIVVQQGMTPSAKQSLVD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 MAPKYILEQFLQQELLINITEHELVPEHVVMTKEEVTELLARYKLRENQLPRIQAGDPVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 MAPKYILEQFLQQELLINITEHELVPEHVVMTKEEVTELLARYKLRENQLPRIQAGDPVA 130 140 150 160 170 180 190 200 210 pF1KB8 RYFGIKRGQVVKIIRPSETAGRYITYRLVQ :::::::::::::::::::::::::::::: NP_002 RYFGIKRGQVVKIIRPSETAGRYITYRLVQ 190 200 210 >>XP_011526372 (OMIM: 180664) PREDICTED: DNA-directed RN (211 aa) initn: 1356 init1: 1064 opt: 1358 Z-score: 1622.5 bits: 307.2 E(85289): 1.2e-83 Smith-Waterman score: 1358; 99.1% identity (99.1% similar) in 211 aa overlap (1-210:1-211) 10 20 30 40 50 60 pF1KB8 MDDEEETYRLWKIRKTIMQLCHDRGYLVTQDELDQTLEEFKAQFGDKPSEGRPRRTDLTV ::::::::::::::::::::::::::::::::::::::::::: :::::::::::::::: XP_011 MDDEEETYRLWKIRKTIMQLCHDRGYLVTQDELDQTLEEFKAQSGDKPSEGRPRRTDLTV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 LVAHNDDPTDQMFVFFPEEPKVGIKTIKVYCQRMQEENITRALIVVQQGMTPSAKQSLVD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LVAHNDDPTDQMFVFFPEEPKVGIKTIKVYCQRMQEENITRALIVVQQGMTPSAKQSLVD 70 80 90 100 110 120 130 140 150 160 170 pF1KB8 MAPKYILEQFLQQELLINITEHELVPEHVVMTKEEVTELLARY-KLRENQLPRIQAGDPV ::::::::::::::::::::::::::::::::::::::::::: :::::::::::::::: XP_011 MAPKYILEQFLQQELLINITEHELVPEHVVMTKEEVTELLARYSKLRENQLPRIQAGDPV 130 140 150 160 170 180 180 190 200 210 pF1KB8 ARYFGIKRGQVVKIIRPSETAGRYITYRLVQ ::::::::::::::::::::::::::::::: XP_011 ARYFGIKRGQVVKIIRPSETAGRYITYRLVQ 190 200 210 >>NP_001303252 (OMIM: 180664) DNA-directed RNA polymeras (117 aa) initn: 739 init1: 739 opt: 739 Z-score: 891.2 bits: 171.1 E(85289): 6.7e-43 Smith-Waterman score: 739; 100.0% identity (100.0% similar) in 117 aa overlap (94-210:1-117) 70 80 90 100 110 120 pF1KB8 HNDDPTDQMFVFFPEEPKVGIKTIKVYCQRMQEENITRALIVVQQGMTPSAKQSLVDMAP :::::::::::::::::::::::::::::: NP_001 MQEENITRALIVVQQGMTPSAKQSLVDMAP 10 20 30 130 140 150 160 170 180 pF1KB8 KYILEQFLQQELLINITEHELVPEHVVMTKEEVTELLARYKLRENQLPRIQAGDPVARYF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KYILEQFLQQELLINITEHELVPEHVVMTKEEVTELLARYKLRENQLPRIQAGDPVARYF 40 50 60 70 80 90 190 200 210 pF1KB8 GIKRGQVVKIIRPSETAGRYITYRLVQ ::::::::::::::::::::::::::: NP_001 GIKRGQVVKIIRPSETAGRYITYRLVQ 100 110 >>NP_001303253 (OMIM: 180664) DNA-directed RNA polymeras (117 aa) initn: 739 init1: 739 opt: 739 Z-score: 891.2 bits: 171.1 E(85289): 6.7e-43 Smith-Waterman score: 739; 100.0% identity (100.0% similar) in 117 aa overlap (94-210:1-117) 70 80 90 100 110 120 pF1KB8 HNDDPTDQMFVFFPEEPKVGIKTIKVYCQRMQEENITRALIVVQQGMTPSAKQSLVDMAP :::::::::::::::::::::::::::::: NP_001 MQEENITRALIVVQQGMTPSAKQSLVDMAP 10 20 30 130 140 150 160 170 180 pF1KB8 KYILEQFLQQELLINITEHELVPEHVVMTKEEVTELLARYKLRENQLPRIQAGDPVARYF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KYILEQFLQQELLINITEHELVPEHVVMTKEEVTELLARYKLRENQLPRIQAGDPVARYF 40 50 60 70 80 90 190 200 210 pF1KB8 GIKRGQVVKIIRPSETAGRYITYRLVQ ::::::::::::::::::::::::::: NP_001 GIKRGQVVKIIRPSETAGRYITYRLVQ 100 110 >>XP_016882372 (OMIM: 180664) PREDICTED: DNA-directed RN (118 aa) initn: 725 init1: 433 opt: 727 Z-score: 876.9 bits: 168.4 E(85289): 4.2e-42 Smith-Waterman score: 727; 99.2% identity (99.2% similar) in 118 aa overlap (94-210:1-118) 70 80 90 100 110 120 pF1KB8 HNDDPTDQMFVFFPEEPKVGIKTIKVYCQRMQEENITRALIVVQQGMTPSAKQSLVDMAP :::::::::::::::::::::::::::::: XP_016 MQEENITRALIVVQQGMTPSAKQSLVDMAP 10 20 30 130 140 150 160 170 180 pF1KB8 KYILEQFLQQELLINITEHELVPEHVVMTKEEVTELLARY-KLRENQLPRIQAGDPVARY :::::::::::::::::::::::::::::::::::::::: ::::::::::::::::::: XP_016 KYILEQFLQQELLINITEHELVPEHVVMTKEEVTELLARYSKLRENQLPRIQAGDPVARY 40 50 60 70 80 90 190 200 210 pF1KB8 FGIKRGQVVKIIRPSETAGRYITYRLVQ :::::::::::::::::::::::::::: XP_016 FGIKRGQVVKIIRPSETAGRYITYRLVQ 100 110 210 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 11:09:30 2016 done: Fri Nov 4 11:09:31 2016 Total Scan time: 4.090 Total Display time: -0.030 Function used was FASTA [36.3.4 Apr, 2011]