FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB8265, 451 aa 1>>>pF1KB8265 451 - 451 aa - 451 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 4.7037+/-0.000381; mu= 20.8504+/- 0.024 mean_var=61.4639+/-12.191, 0's: 0 Z-trim(111.5): 67 B-trim: 9 in 1/49 Lambda= 0.163593 statistics sampled from 20097 (20166) to 20097 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.62), E-opt: 0.2 (0.236), width: 16 Scan time: 6.060 The best scores are: opt bits E(85289) NP_006073 (OMIM: 602530) tubulin alpha-1B chain [H ( 451) 3044 727.3 2e-209 NP_001257328 (OMIM: 602529,611603) tubulin alpha-1 ( 451) 3036 725.4 7.5e-209 NP_006000 (OMIM: 602529,611603) tubulin alpha-1A c ( 451) 3036 725.4 7.5e-209 NP_005992 (OMIM: 602528) tubulin alpha-3C/D chain ( 450) 2975 711.0 1.6e-204 NP_005991 (OMIM: 191110,616208) tubulin alpha-4A c ( 448) 2941 703.0 4.2e-202 NP_001265481 (OMIM: 191110,616208) tubulin alpha-4 ( 433) 2839 678.9 7.3e-195 NP_001257329 (OMIM: 602529,611603) tubulin alpha-1 ( 416) 2774 663.5 2.9e-190 NP_061816 (OMIM: 605742,613180) tubulin alpha-8 ch ( 449) 2774 663.5 3.1e-190 NP_001180343 (OMIM: 605742,613180) tubulin alpha-8 ( 383) 2414 578.5 1e-164 XP_016860313 (OMIM: 191110,616208) PREDICTED: tubu ( 295) 1933 464.9 1.3e-130 NP_006078 (OMIM: 602662) tubulin beta-4A chain iso ( 444) 1290 313.3 8.3e-85 NP_001276058 (OMIM: 602662) tubulin beta-4A chain ( 444) 1290 313.3 8.3e-85 NP_001276056 (OMIM: 602662) tubulin beta-4A chain ( 489) 1290 313.3 9e-85 NP_001276052 (OMIM: 602662) tubulin beta-4A chain ( 495) 1290 313.3 9.1e-85 NP_821133 (OMIM: 156610,191130,615771) tubulin bet ( 444) 1288 312.8 1.2e-84 NP_006079 (OMIM: 602660) tubulin beta-4B chain [Ho ( 445) 1288 312.8 1.2e-84 NP_001060 (OMIM: 615101,615763) tubulin beta-2A ch ( 445) 1277 310.2 7e-84 NP_821080 (OMIM: 610031,612850) tubulin beta-2B ch ( 445) 1275 309.8 9.7e-84 NP_115914 (OMIM: 615103) tubulin beta-6 chain isof ( 446) 1274 309.5 1.1e-83 NP_001290453 (OMIM: 615103) tubulin beta-6 chain i ( 446) 1274 309.5 1.1e-83 NP_006077 (OMIM: 600638,602661,614039) tubulin bet ( 450) 1273 309.3 1.4e-83 NP_817124 (OMIM: 616768,616780) tubulin beta-8 cha ( 444) 1245 302.7 1.3e-81 NP_001280141 (OMIM: 156610,191130,615771) tubulin ( 464) 1226 298.2 3e-80 NP_110400 (OMIM: 612901,613112) tubulin beta-1 cha ( 451) 1198 291.6 2.9e-78 NP_001280143 (OMIM: 156610,191130,615771) tubulin ( 400) 1157 281.9 2.2e-75 XP_016883574 (OMIM: 612901,613112) PREDICTED: tubu ( 429) 1115 272.0 2.2e-72 NP_001276060 (OMIM: 602662) tubulin beta-4A chain ( 372) 1087 265.3 1.9e-70 NP_001276059 (OMIM: 602662) tubulin beta-4A chain ( 372) 1087 265.3 1.9e-70 NP_001280145 (OMIM: 156610,191130,615771) tubulin ( 372) 1077 263.0 9.9e-70 NP_001280144 (OMIM: 156610,191130,615771) tubulin ( 372) 1077 263.0 9.9e-70 NP_001184110 (OMIM: 600638,602661,614039) tubulin ( 378) 1074 262.3 1.6e-69 NP_001290456 (OMIM: 615103) tubulin beta-6 chain i ( 374) 1073 262.0 1.9e-69 XP_011517761 (OMIM: 616768,616780) PREDICTED: tubu ( 372) 1059 258.7 1.9e-68 NP_001290457 (OMIM: 615103) tubulin beta-6 chain i ( 381) 1011 247.4 4.9e-65 NP_001297244 (OMIM: 615101,615763) tubulin beta-2A ( 360) 1010 247.1 5.6e-65 NP_001290455 (OMIM: 615103) tubulin beta-6 chain i ( 409) 998 244.4 4.4e-64 XP_016871682 (OMIM: 616768,616780) PREDICTED: tubu ( 332) 919 225.6 1.5e-58 XP_016871681 (OMIM: 616768,616780) PREDICTED: tubu ( 332) 919 225.6 1.5e-58 NP_001061 (OMIM: 191135,615412) tubulin gamma-1 ch ( 451) 820 202.4 2.1e-51 NP_057521 (OMIM: 605785) tubulin gamma-2 chain iso ( 451) 813 200.7 6.5e-51 NP_001290458 (OMIM: 615103) tubulin beta-6 chain i ( 300) 788 194.7 2.9e-49 NP_001290459 (OMIM: 615103) tubulin beta-6 chain i ( 300) 788 194.7 2.9e-49 XP_011517762 (OMIM: 616768,616780) PREDICTED: tubu ( 291) 739 183.1 8.5e-46 NP_001307438 (OMIM: 605785) tubulin gamma-2 chain ( 460) 545 137.5 7.3e-32 NP_057346 (OMIM: 607345) tubulin epsilon chain [Ho ( 475) 444 113.6 1.1e-24 XP_016879942 (OMIM: 605785) PREDICTED: tubulin gam ( 298) 438 112.1 2.1e-24 XP_011522916 (OMIM: 605785) PREDICTED: tubulin gam ( 298) 438 112.1 2.1e-24 XP_016879944 (OMIM: 605785) PREDICTED: tubulin gam ( 274) 412 105.9 1.4e-22 XP_016879946 (OMIM: 605785) PREDICTED: tubulin gam ( 274) 412 105.9 1.4e-22 XP_016879945 (OMIM: 605785) PREDICTED: tubulin gam ( 274) 412 105.9 1.4e-22 >>NP_006073 (OMIM: 602530) tubulin alpha-1B chain [Homo (451 aa) initn: 3044 init1: 3044 opt: 3044 Z-score: 3880.7 bits: 727.3 E(85289): 2e-209 Smith-Waterman score: 3044; 100.0% identity (100.0% similar) in 451 aa overlap (1-451:1-451) 10 20 30 40 50 60 pF1KB8 MRECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIGGGDDSFNTFFSETGAGK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 MRECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIGGGDDSFNTFFSETGAGK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 HVPRAVFVDLEPTVIDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIIDLVLD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 HVPRAVFVDLEPTVIDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIIDLVLD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 RIRKLADQCTGLQGFLVFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFSIYPAPQVSTA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 RIRKLADQCTGLQGFLVFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFSIYPAPQVSTA 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 VVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLISQIVSSITA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 VVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLISQIVSSITA 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 SLRFDGALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYHEQLSVAEITNACFEPAN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 SLRFDGALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYHEQLSVAEITNACFEPAN 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 QMVKCDPRHGKYMACCLLYRGDVVPKDVNAAIATIKTKRSIQFVDWCPTGFKVGINYQPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 QMVKCDPRHGKYMACCLLYRGDVVPKDVNAAIATIKTKRSIQFVDWCPTGFKVGINYQPP 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB8 TVVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 TVVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSE 370 380 390 400 410 420 430 440 450 pF1KB8 AREDMAALEKDYEEVGVDSVEGEGEEEGEEY ::::::::::::::::::::::::::::::: NP_006 AREDMAALEKDYEEVGVDSVEGEGEEEGEEY 430 440 450 >>NP_001257328 (OMIM: 602529,611603) tubulin alpha-1A ch (451 aa) initn: 3036 init1: 3036 opt: 3036 Z-score: 3870.5 bits: 725.4 E(85289): 7.5e-209 Smith-Waterman score: 3036; 99.6% identity (100.0% similar) in 451 aa overlap (1-451:1-451) 10 20 30 40 50 60 pF1KB8 MRECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIGGGDDSFNTFFSETGAGK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MRECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIGGGDDSFNTFFSETGAGK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 HVPRAVFVDLEPTVIDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIIDLVLD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HVPRAVFVDLEPTVIDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIIDLVLD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 RIRKLADQCTGLQGFLVFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFSIYPAPQVSTA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RIRKLADQCTGLQGFLVFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFSIYPAPQVSTA 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 VVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLISQIVSSITA :::::::::::::::::::::::::::::::::::::::::::::::::::.:::::::: NP_001 VVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLIGQIVSSITA 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 SLRFDGALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYHEQLSVAEITNACFEPAN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SLRFDGALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYHEQLSVAEITNACFEPAN 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 QMVKCDPRHGKYMACCLLYRGDVVPKDVNAAIATIKTKRSIQFVDWCPTGFKVGINYQPP :::::::::::::::::::::::::::::::::::::::.:::::::::::::::::::: NP_001 QMVKCDPRHGKYMACCLLYRGDVVPKDVNAAIATIKTKRTIQFVDWCPTGFKVGINYQPP 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB8 TVVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TVVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSE 370 380 390 400 410 420 430 440 450 pF1KB8 AREDMAALEKDYEEVGVDSVEGEGEEEGEEY ::::::::::::::::::::::::::::::: NP_001 AREDMAALEKDYEEVGVDSVEGEGEEEGEEY 430 440 450 >>NP_006000 (OMIM: 602529,611603) tubulin alpha-1A chain (451 aa) initn: 3036 init1: 3036 opt: 3036 Z-score: 3870.5 bits: 725.4 E(85289): 7.5e-209 Smith-Waterman score: 3036; 99.6% identity (100.0% similar) in 451 aa overlap (1-451:1-451) 10 20 30 40 50 60 pF1KB8 MRECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIGGGDDSFNTFFSETGAGK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 MRECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIGGGDDSFNTFFSETGAGK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 HVPRAVFVDLEPTVIDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIIDLVLD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 HVPRAVFVDLEPTVIDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIIDLVLD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 RIRKLADQCTGLQGFLVFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFSIYPAPQVSTA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 RIRKLADQCTGLQGFLVFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFSIYPAPQVSTA 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 VVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLISQIVSSITA :::::::::::::::::::::::::::::::::::::::::::::::::::.:::::::: NP_006 VVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLIGQIVSSITA 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 SLRFDGALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYHEQLSVAEITNACFEPAN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 SLRFDGALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYHEQLSVAEITNACFEPAN 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 QMVKCDPRHGKYMACCLLYRGDVVPKDVNAAIATIKTKRSIQFVDWCPTGFKVGINYQPP :::::::::::::::::::::::::::::::::::::::.:::::::::::::::::::: NP_006 QMVKCDPRHGKYMACCLLYRGDVVPKDVNAAIATIKTKRTIQFVDWCPTGFKVGINYQPP 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB8 TVVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 TVVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSE 370 380 390 400 410 420 430 440 450 pF1KB8 AREDMAALEKDYEEVGVDSVEGEGEEEGEEY ::::::::::::::::::::::::::::::: NP_006 AREDMAALEKDYEEVGVDSVEGEGEEEGEEY 430 440 450 >>NP_005992 (OMIM: 602528) tubulin alpha-3C/D chain [Hom (450 aa) initn: 2959 init1: 2959 opt: 2975 Z-score: 3792.7 bits: 711.0 E(85289): 1.6e-204 Smith-Waterman score: 2975; 97.1% identity (99.6% similar) in 451 aa overlap (1-451:1-450) 10 20 30 40 50 60 pF1KB8 MRECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIGGGDDSFNTFFSETGAGK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 MRECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIGGGDDSFNTFFSETGAGK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 HVPRAVFVDLEPTVIDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIIDLVLD ::::::::::::::.:::::::::::::::::::::::::::::::::::::::.::::: NP_005 HVPRAVFVDLEPTVVDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIVDLVLD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 RIRKLADQCTGLQGFLVFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFSIYPAPQVSTA ::::::: ::::::::.::::::::::::.:::::::::::::::::::.:::::::::: NP_005 RIRKLADLCTGLQGFLIFHSFGGGTGSGFASLLMERLSVDYGKKSKLEFAIYPAPQVSTA 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 VVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLISQIVSSITA :::::::::::::::::::::::::::::::::::::::::::::::::::.:::::::: NP_005 VVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLIGQIVSSITA 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 SLRFDGALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYHEQLSVAEITNACFEPAN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 SLRFDGALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYHEQLSVAEITNACFEPAN 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 QMVKCDPRHGKYMACCLLYRGDVVPKDVNAAIATIKTKRSIQFVDWCPTGFKVGINYQPP ::::::::::::::::.::::::::::::::::::::::.:::::::::::::::::::: NP_005 QMVKCDPRHGKYMACCMLYRGDVVPKDVNAAIATIKTKRTIQFVDWCPTGFKVGINYQPP 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB8 TVVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 TVVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSE 370 380 390 400 410 420 430 440 450 pF1KB8 AREDMAALEKDYEEVGVDSVEGEGEEEGEEY ::::.::::::::::::::::.:.:: :::: NP_005 AREDLAALEKDYEEVGVDSVEAEAEE-GEEY 430 440 450 >>NP_005991 (OMIM: 191110,616208) tubulin alpha-4A chain (448 aa) initn: 2935 init1: 2935 opt: 2941 Z-score: 3749.3 bits: 703.0 E(85289): 4.2e-202 Smith-Waterman score: 2941; 96.4% identity (98.4% similar) in 450 aa overlap (1-450:1-448) 10 20 30 40 50 60 pF1KB8 MRECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIGGGDDSFNTFFSETGAGK ::::::.::::::::.:::::::::::::::::::::::::::::::::.::: :::::: NP_005 MRECISVHVGQAGVQMGNACWELYCLEHGIQPDGQMPSDKTIGGGDDSFTTFFCETGAGK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 HVPRAVFVDLEPTVIDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIIDLVLD :::::::::::::::::.:.: :::::::::::::::::::::::::::::::::: ::: NP_005 HVPRAVFVDLEPTVIDEIRNGPYRQLFHPEQLITGKEDAANNYARGHYTIGKEIIDPVLD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 RIRKLADQCTGLQGFLVFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFSIYPAPQVSTA :::::.:::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 RIRKLSDQCTGLQGFLVFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFSIYPAPQVSTA 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 VVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLISQIVSSITA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 VVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLISQIVSSITA 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 SLRFDGALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYHEQLSVAEITNACFEPAN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 SLRFDGALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYHEQLSVAEITNACFEPAN 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 QMVKCDPRHGKYMACCLLYRGDVVPKDVNAAIATIKTKRSIQFVDWCPTGFKVGINYQPP :::::::::::::::::::::::::::::::::.:::::::::::::::::::::::::: NP_005 QMVKCDPRHGKYMACCLLYRGDVVPKDVNAAIAAIKTKRSIQFVDWCPTGFKVGINYQPP 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB8 TVVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 TVVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSE 370 380 390 400 410 420 430 440 450 pF1KB8 AREDMAALEKDYEEVGVDSVEGEGEEEGEEY ::::::::::::::::.:: : :.:::: NP_005 AREDMAALEKDYEEVGIDSYED--EDEGEE 430 440 >>NP_001265481 (OMIM: 191110,616208) tubulin alpha-4A ch (433 aa) initn: 2831 init1: 2831 opt: 2839 Z-score: 3619.4 bits: 678.9 E(85289): 7.3e-195 Smith-Waterman score: 2839; 96.6% identity (98.4% similar) in 435 aa overlap (16-450:1-433) 10 20 30 40 50 60 pF1KB8 MRECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIGGGDDSFNTFFSETGAGK .:::::::::::::::::::::::::::::::::.::: :::::: NP_001 MGNACWELYCLEHGIQPDGQMPSDKTIGGGDDSFTTFFCETGAGK 10 20 30 40 70 80 90 100 110 120 pF1KB8 HVPRAVFVDLEPTVIDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIIDLVLD :::::::::::::::::.:.: :::::::::::::::::::::::::::::::::: ::: NP_001 HVPRAVFVDLEPTVIDEIRNGPYRQLFHPEQLITGKEDAANNYARGHYTIGKEIIDPVLD 50 60 70 80 90 100 130 140 150 160 170 180 pF1KB8 RIRKLADQCTGLQGFLVFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFSIYPAPQVSTA :::::.:::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RIRKLSDQCTGLQGFLVFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFSIYPAPQVSTA 110 120 130 140 150 160 190 200 210 220 230 240 pF1KB8 VVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLISQIVSSITA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLISQIVSSITA 170 180 190 200 210 220 250 260 270 280 290 300 pF1KB8 SLRFDGALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYHEQLSVAEITNACFEPAN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SLRFDGALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYHEQLSVAEITNACFEPAN 230 240 250 260 270 280 310 320 330 340 350 360 pF1KB8 QMVKCDPRHGKYMACCLLYRGDVVPKDVNAAIATIKTKRSIQFVDWCPTGFKVGINYQPP :::::::::::::::::::::::::::::::::.:::::::::::::::::::::::::: NP_001 QMVKCDPRHGKYMACCLLYRGDVVPKDVNAAIAAIKTKRSIQFVDWCPTGFKVGINYQPP 290 300 310 320 330 340 370 380 390 400 410 420 pF1KB8 TVVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TVVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSE 350 360 370 380 390 400 430 440 450 pF1KB8 AREDMAALEKDYEEVGVDSVEGEGEEEGEEY ::::::::::::::::.:: : : .:::: NP_001 AREDMAALEKDYEEVGIDSYEDE--DEGEE 410 420 430 >>NP_001257329 (OMIM: 602529,611603) tubulin alpha-1A ch (416 aa) initn: 2774 init1: 2774 opt: 2774 Z-score: 3536.8 bits: 663.5 E(85289): 2.9e-190 Smith-Waterman score: 2774; 99.5% identity (100.0% similar) in 416 aa overlap (36-451:1-416) 10 20 30 40 50 60 pF1KB8 SIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIGGGDDSFNTFFSETGAGKHVPRA :::::::::::::::::::::::::::::: NP_001 MPSDKTIGGGDDSFNTFFSETGAGKHVPRA 10 20 30 70 80 90 100 110 120 pF1KB8 VFVDLEPTVIDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIIDLVLDRIRKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VFVDLEPTVIDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIIDLVLDRIRKL 40 50 60 70 80 90 130 140 150 160 170 180 pF1KB8 ADQCTGLQGFLVFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFSIYPAPQVSTAVVEPY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ADQCTGLQGFLVFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFSIYPAPQVSTAVVEPY 100 110 120 130 140 150 190 200 210 220 230 240 pF1KB8 NSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLISQIVSSITASLRFD ::::::::::::::::::::::::::::::::::::::::::::::.::::::::::::: NP_001 NSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLIGQIVSSITASLRFD 160 170 180 190 200 210 250 260 270 280 290 300 pF1KB8 GALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYHEQLSVAEITNACFEPANQMVKC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYHEQLSVAEITNACFEPANQMVKC 220 230 240 250 260 270 310 320 330 340 350 360 pF1KB8 DPRHGKYMACCLLYRGDVVPKDVNAAIATIKTKRSIQFVDWCPTGFKVGINYQPPTVVPG ::::::::::::::::::::::::::::::::::.::::::::::::::::::::::::: NP_001 DPRHGKYMACCLLYRGDVVPKDVNAAIATIKTKRTIQFVDWCPTGFKVGINYQPPTVVPG 280 290 300 310 320 330 370 380 390 400 410 420 pF1KB8 GDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDM 340 350 360 370 380 390 430 440 450 pF1KB8 AALEKDYEEVGVDSVEGEGEEEGEEY :::::::::::::::::::::::::: NP_001 AALEKDYEEVGVDSVEGEGEEEGEEY 400 410 >>NP_061816 (OMIM: 605742,613180) tubulin alpha-8 chain (449 aa) initn: 2767 init1: 2767 opt: 2774 Z-score: 3536.3 bits: 663.5 E(85289): 3.1e-190 Smith-Waterman score: 2774; 89.8% identity (96.7% similar) in 451 aa overlap (1-451:1-449) 10 20 30 40 50 60 pF1KB8 MRECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIGGGDDSFNTFFSETGAGK ::::::.::::::::::::::::.::::::: :: . .. . . ::::.::::::: :: NP_061 MRECISVHVGQAGVQIGNACWELFCLEHGIQADGTFDAQASKINDDDSFTTFFSETGNGK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 HVPRAVFVDLEPTVIDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIIDLVLD ::::::..::::::.::::.:::::::::::::::::::::::::::::.::: :::::: NP_061 HVPRAVMIDLEPTVVDEVRAGTYRQLFHPEQLITGKEDAANNYARGHYTVGKESIDLVLD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 RIRKLADQCTGLQGFLVFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFSIYPAPQVSTA :::::.: :.::::::.:::::::::::::::::::::.::::::::::.:::::::::: NP_061 RIRKLTDACSGLQGFLIFHSFGGGTGSGFTSLLMERLSLDYGKKSKLEFAIYPAPQVSTA 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 VVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLISQIVSSITA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_061 VVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLISQIVSSITA 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 SLRFDGALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYHEQLSVAEITNACFEPAN :::::::::::::::::::::::::::::.::::.:::::::::::::::::..:::: . NP_061 SLRFDGALNVDLTEFQTNLVPYPRIHFPLVTYAPIISAEKAYHEQLSVAEITSSCFEPNS 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 QMVKCDPRHGKYMACCLLYRGDVVPKDVNAAIATIKTKRSIQFVDWCPTGFKVGINYQPP ::::::::::::::::.::::::::::::.:::.:::::.:::::::::::::::::::: NP_061 QMVKCDPRHGKYMACCMLYRGDVVPKDVNVAIAAIKTKRTIQFVDWCPTGFKVGINYQPP 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB8 TVVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_061 TVVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSE 370 380 390 400 410 420 430 440 450 pF1KB8 AREDMAALEKDYEEVGVDSVEGEGEEEGEEY ::::.:::::::::::.:: : :.: :::. NP_061 AREDLAALEKDYEEVGTDSFEEENE--GEEF 430 440 >>NP_001180343 (OMIM: 605742,613180) tubulin alpha-8 cha (383 aa) initn: 2403 init1: 2403 opt: 2414 Z-score: 3078.1 bits: 578.5 E(85289): 1e-164 Smith-Waterman score: 2414; 92.4% identity (98.2% similar) in 384 aa overlap (68-451:2-383) 40 50 60 70 80 90 pF1KB8 SDKTIGGGDDSFNTFFSETGAGKHVPRAVFVDLEPTVIDEVRTGTYRQLFHPEQLITGKE .::::::.::::.::::::::::::::::: NP_001 MIDLEPTVVDEVRAGTYRQLFHPEQLITGKE 10 20 30 100 110 120 130 140 150 pF1KB8 DAANNYARGHYTIGKEIIDLVLDRIRKLADQCTGLQGFLVFHSFGGGTGSGFTSLLMERL ::::::::::::.::: :::::::::::.: :.::::::.:::::::::::::::::::: NP_001 DAANNYARGHYTVGKESIDLVLDRIRKLTDACSGLQGFLIFHSFGGGTGSGFTSLLMERL 40 50 60 70 80 90 160 170 180 190 200 210 pF1KB8 SVDYGKKSKLEFSIYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNL :.::::::::::.::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SLDYGKKSKLEFAIYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNL 100 110 120 130 140 150 220 230 240 250 260 270 pF1KB8 DIERPTYTNLNRLISQIVSSITASLRFDGALNVDLTEFQTNLVPYPRIHFPLATYAPVIS ::::::::::::::::::::::::::::::::::::::::::::::::::::.::::.:: NP_001 DIERPTYTNLNRLISQIVSSITASLRFDGALNVDLTEFQTNLVPYPRIHFPLVTYAPIIS 160 170 180 190 200 210 280 290 300 310 320 330 pF1KB8 AEKAYHEQLSVAEITNACFEPANQMVKCDPRHGKYMACCLLYRGDVVPKDVNAAIATIKT :::::::::::::::..:::: .::::::::::::::::.::::::::::::.:::.::: NP_001 AEKAYHEQLSVAEITSSCFEPNSQMVKCDPRHGKYMACCMLYRGDVVPKDVNVAIAAIKT 220 230 240 250 260 270 340 350 360 370 380 390 pF1KB8 KRSIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDL ::.::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KRTIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDL 280 290 300 310 320 330 400 410 420 430 440 450 pF1KB8 MYAKRAFVHWYVGEGMEEGEFSEAREDMAALEKDYEEVGVDSVEGEGEEEGEEY :::::::::::::::::::::::::::.:::::::::::.:: : :.: :::. NP_001 MYAKRAFVHWYVGEGMEEGEFSEAREDLAALEKDYEEVGTDSFEEENE--GEEF 340 350 360 370 380 >>XP_016860313 (OMIM: 191110,616208) PREDICTED: tubulin (295 aa) initn: 1927 init1: 1927 opt: 1933 Z-score: 2466.1 bits: 464.9 E(85289): 1.3e-130 Smith-Waterman score: 1933; 97.6% identity (98.7% similar) in 297 aa overlap (154-450:1-295) 130 140 150 160 170 180 pF1KB8 KLADQCTGLQGFLVFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFSIYPAPQVSTAVVE :::::::::::::::::::::::::::::: XP_016 MERLSVDYGKKSKLEFSIYPAPQVSTAVVE 10 20 30 190 200 210 220 230 240 pF1KB8 PYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLISQIVSSITASLR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLISQIVSSITASLR 40 50 60 70 80 90 250 260 270 280 290 300 pF1KB8 FDGALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYHEQLSVAEITNACFEPANQMV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FDGALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYHEQLSVAEITNACFEPANQMV 100 110 120 130 140 150 310 320 330 340 350 360 pF1KB8 KCDPRHGKYMACCLLYRGDVVPKDVNAAIATIKTKRSIQFVDWCPTGFKVGINYQPPTVV ::::::::::::::::::::::::::::::.::::::::::::::::::::::::::::: XP_016 KCDPRHGKYMACCLLYRGDVVPKDVNAAIAAIKTKRSIQFVDWCPTGFKVGINYQPPTVV 160 170 180 190 200 210 370 380 390 400 410 420 pF1KB8 PGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEARE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEARE 220 230 240 250 260 270 430 440 450 pF1KB8 DMAALEKDYEEVGVDSVEGEGEEEGEEY :::::::::::::.:: : : .:::: XP_016 DMAALEKDYEEVGIDSYEDE--DEGEE 280 290 451 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 11:10:47 2016 done: Fri Nov 4 11:10:48 2016 Total Scan time: 6.060 Total Display time: 0.050 Function used was FASTA [36.3.4 Apr, 2011]