FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB8266, 190 aa 1>>>pF1KB8266 190 - 190 aa - 190 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 4.9852+/-0.000327; mu= 14.3895+/- 0.020 mean_var=56.9821+/-11.210, 0's: 0 Z-trim(115.1): 41 B-trim: 395 in 1/54 Lambda= 0.169905 statistics sampled from 25346 (25387) to 25346 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.692), E-opt: 0.2 (0.298), width: 16 Scan time: 5.490 The best scores are: opt bits E(85289) NP_000945 (OMIM: 176803) prostaglandin-H2 D-isomer ( 190) 1272 319.6 1.9e-87 NP_005555 (OMIM: 600181) neutrophil gelatinase-ass ( 198) 323 87.0 2.1e-17 NP_001624 (OMIM: 176870) protein AMBP preproprotei ( 352) 261 71.9 1.3e-12 NP_848631 (OMIM: 612905) epididymal-specific lipoc ( 192) 251 69.3 4.3e-12 XP_016870120 (OMIM: 612905) PREDICTED: epididymal- ( 227) 249 68.9 6.9e-12 XP_006717128 (OMIM: 612905) PREDICTED: epididymal- ( 355) 249 69.0 1e-11 XP_011516864 (OMIM: 612905) PREDICTED: epididymal- ( 355) 249 69.0 1e-11 XP_011516862 (OMIM: 612905) PREDICTED: epididymal- ( 382) 249 69.0 1.1e-11 XP_011516863 (OMIM: 612905) PREDICTED: epididymal- ( 383) 249 69.0 1.1e-11 XP_016870121 (OMIM: 612905) PREDICTED: epididymal- ( 184) 170 49.4 3.9e-06 NP_000597 (OMIM: 120930) complement component C8 g ( 202) 167 48.7 7e-06 NP_945184 (OMIM: 609379) epididymal-specific lipoc ( 163) 159 46.7 2.3e-05 NP_055397 (OMIM: 164320) odorant-binding protein 2 ( 170) 146 43.5 0.00021 >>NP_000945 (OMIM: 176803) prostaglandin-H2 D-isomerase (190 aa) initn: 1272 init1: 1272 opt: 1272 Z-score: 1690.8 bits: 319.6 E(85289): 1.9e-87 Smith-Waterman score: 1272; 100.0% identity (100.0% similar) in 190 aa overlap (1-190:1-190) 10 20 30 40 50 60 pF1KB8 MATHHTLWMGLALLGVLGDLQAAPEAQVSVQPNFQQDKFLGRWFSAGLASNSSWLREKKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 MATHHTLWMGLALLGVLGDLQAAPEAQVSVQPNFQQDKFLGRWFSAGLASNSSWLREKKA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 ALSMCKSVVAPATDGGLNLTSTFLRKNQCETRTMLLQPAGSLGSYSYRSPHWGSTYSVSV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 ALSMCKSVVAPATDGGLNLTSTFLRKNQCETRTMLLQPAGSLGSYSYRSPHWGSTYSVSV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 VETDYDQYALLYSQGSKGPGEDFRMATLYSRTQTPRAELKEKFTAFCKAQGFTEDTIVFL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 VETDYDQYALLYSQGSKGPGEDFRMATLYSRTQTPRAELKEKFTAFCKAQGFTEDTIVFL 130 140 150 160 170 180 190 pF1KB8 PQTDKCMTEQ :::::::::: NP_000 PQTDKCMTEQ 190 >>NP_005555 (OMIM: 600181) neutrophil gelatinase-associa (198 aa) initn: 281 init1: 99 opt: 323 Z-score: 433.4 bits: 87.0 E(85289): 2.1e-17 Smith-Waterman score: 360; 35.8% identity (62.7% similar) in 193 aa overlap (7-187:6-196) 10 20 30 40 50 pF1KB8 MATHHTLWMGLALLGVL--------GDLQAAPE-AQVSVQPNFQQDKFLGRWFSAGLASN ::.::::::.: .:: :: ..: .: :::...: :.:. .:::.: NP_005 MPLGLLWLGLALLGALHAQAQDSTSDLIPAPPLSKVPLQQNFQDNQFQGKWYVVGLAGN 10 20 30 40 50 60 70 80 90 100 pF1KB8 SSWLREKKAALSMCKSVVAPATDGGLNLTSTFLRKNQCETRTMLLQPAGSLGSYSY---R . ::: : .: .. : . :.::...::..:. . :. . : .. . NP_005 AI-LREDKDPQKMYATIYELKEDKSYNVTSVLFRKKKCDYWIRTFVPGCQPGEFTLGNIK 60 70 80 90 100 110 110 120 130 140 150 160 pF1KB8 SPHWGSTYSVSVVETDYDQYALLYSQGSKGPGEDFRMATLYSRTQTPRAELKEKFTAFCK : ..: : :: :.:.:.:... . . : :.. :::.::. .::::.: : : NP_005 SYPGLTSYLVRVVSTNYNQHAMVFFKKVSQNREYFKI-TLYGRTKELTSELKENFIRFSK 120 130 140 150 160 170 170 180 190 pF1KB8 AQGFTEDTIVFLPQTDKCMTEQ . :. :. ::: :.:. NP_005 SLGLPENHIVFPVPIDQCIDG 180 190 >>NP_001624 (OMIM: 176870) protein AMBP preproprotein [H (352 aa) initn: 244 init1: 175 opt: 261 Z-score: 347.4 bits: 71.9 E(85289): 1.3e-12 Smith-Waterman score: 261; 27.0% identity (61.8% similar) in 178 aa overlap (12-187:13-189) 10 20 30 40 50 pF1KB8 MATHHTLWMGLALLGVLGDLQAAPEAQVSVQPNFQQDKFLGRWFSAGLASNSSWLREKK : :.: . .: ...:: ::. ... :.:.. ...:. ::.. NP_001 MRSLGALLLLLSACLAVSAGPVPTPPDNIQVQENFNISRIYGKWYNLAIGSTCPWLKKIM 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB8 AALSMCKSVVAP-ATDGGLNLTSTFLRKNQCETRTMLLQPAGSLGSYSYRSPHWGSTYSV ... :.. ::.. ...::: ::. :: . . . . :.. :.. .:. :. NP_001 DRMTVSTLVLGEGATEAEISMTSTRWRKGVCEETSGAYEKTDTDGKFLYHKSKWNITMES 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB8 SVVETDYDQYALLYSQG-SKGPGEDFRMATLYSRTQTPRAELKEKFTAFCKAQGFTEDTI ::.:.::.::.. .. :. : . : ::.:. : : . : . .. :. ::.: NP_001 YVVHTNYDEYAIFLTKKFSRHHGPTIT-AKLYGRAPQLRETLLQDFRVVAQGVGIPEDSI 130 140 150 160 170 180 190 pF1KB8 VFLPQTDKCMTEQ . . .:. NP_001 FTMADRGECVPGEQEPEPILIPRVRRAVLPQEEEGSGGGQLVTEVTKKEDSCQLGYSAGP 180 190 200 210 220 230 >>NP_848631 (OMIM: 612905) epididymal-specific lipocalin (192 aa) initn: 208 init1: 113 opt: 251 Z-score: 338.2 bits: 69.3 E(85289): 4.3e-12 Smith-Waterman score: 251; 29.3% identity (60.1% similar) in 188 aa overlap (7-186:7-192) 10 20 30 40 50 60 pF1KB8 MATHHTLWMGLALLGVLGDLQAAPEAQVSVQPNFQQDKFLGRWFSAGLASNSSWLREKKA ::. :.:: :: .: . .:: ..: :.:: :::.:: . :..: NP_848 MRLLCGLWLWLSLLKVLQAQTPTPLPLPPPMQSFQGNQFQGEWFVLGLAGNS-FRPEHRA 10 20 30 40 50 70 80 90 100 110 pF1KB8 ALSMCKSVVAPATDGGLNLTSTFLRKNQCETRTMLLQPAGSLGSYSY-RSPHWGSTYSVS :. .. . :: ... ... : ..:.: ...: ::.. :... .. . :. . NP_848 LLNAFTATFELSDDGRFEVWNAMTRGQHCDTWSYVLIPAAQPGQFTVDHGVEPGADREET 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB8 -VVETDYDQYALLYSQGSKGPGEDFRMATLYSRTQTPRAELKEKFTAFCKAQGFTEDTIV ::..:: :.::. :. . .:.. : : . : ..: . .:::...:.:: NP_848 RVVDSDYTQFALMLSRRHTSRLAVLRISLLGRSWLLPPGTL-DQFICLGRAQGLSDDNIV 120 130 140 150 160 170 180 190 pF1KB8 F------LPQTDKCMTEQ : ::.. : NP_848 FPDVTGWSPQASVC 180 190 >>XP_016870120 (OMIM: 612905) PREDICTED: epididymal-spec (227 aa) initn: 157 init1: 113 opt: 249 Z-score: 334.4 bits: 68.9 E(85289): 6.9e-12 Smith-Waterman score: 249; 29.7% identity (61.7% similar) in 175 aa overlap (7-179:35-207) 10 20 30 pF1KB8 MATHHTLWMGLALLGVLGDLQAAPEAQVSVQPNFQQ ::. :.:: :: .: . .:: XP_016 RWVSGSPAHGHFLLSVPVGPAAARMRLLCGLWLWLSLLKVLQAQTPTPLPLPPPMQSFQG 10 20 30 40 50 60 40 50 60 70 80 90 pF1KB8 DKFLGRWFSAGLASNSSWLREKKAALSMCKSVVAPATDGGLNLTSTFLRKNQCETRTMLL ..: :.:: :::.:: . :..: :. .. . :: ... ... : ..:.: ...: XP_016 NQFQGEWFVLGLAGNS-FRPEHRALLNAFTATFELSDDGRFEVWNAMTRGQHCDTWSYVL 70 80 90 100 110 120 100 110 120 130 140 150 pF1KB8 QPAGSLGSYSY-RSPHWGSTYSVS-VVETDYDQYALLYSQGSKGPGEDFRMATLYSRTQT ::.. :... .. . :. . ::..:: :.::. :. . .:.. : XP_016 IPAAQPGQFTVDHGVEPGADREETRVVDSDYTQFALMLSRRHTSRLAVLRISLLGRSWLL 130 140 150 160 170 180 160 170 180 190 pF1KB8 PRAELKEKFTAFCKAQGFTEDTIVFLPQTDKCMTEQ : . : ..: . .:::...:.::: XP_016 PPGTL-DQFICLGRAQGLSDDNIVFPDVTGGALDLSSLPWVAAPA 190 200 210 220 >>XP_006717128 (OMIM: 612905) PREDICTED: epididymal-spec (355 aa) initn: 157 init1: 113 opt: 249 Z-score: 331.5 bits: 69.0 E(85289): 1e-11 Smith-Waterman score: 249; 29.7% identity (61.7% similar) in 175 aa overlap (7-179:7-179) 10 20 30 40 50 60 pF1KB8 MATHHTLWMGLALLGVLGDLQAAPEAQVSVQPNFQQDKFLGRWFSAGLASNSSWLREKKA ::. :.:: :: .: . .:: ..: :.:: :::.:: . :..: XP_006 MRLLCGLWLWLSLLKVLQAQTPTPLPLPPPMQSFQGNQFQGEWFVLGLAGNS-FRPEHRA 10 20 30 40 50 70 80 90 100 110 pF1KB8 ALSMCKSVVAPATDGGLNLTSTFLRKNQCETRTMLLQPAGSLGSYSY-RSPHWGSTYSVS :. .. . :: ... ... : ..:.: ...: ::.. :... .. . :. . XP_006 LLNAFTATFELSDDGRFEVWNAMTRGQHCDTWSYVLIPAAQPGQFTVDHGVEPGADREET 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB8 -VVETDYDQYALLYSQGSKGPGEDFRMATLYSRTQTPRAELKEKFTAFCKAQGFTEDTIV ::..:: :.::. :. . .:.. : : . : ..: . .:::...:.:: XP_006 RVVDSDYTQFALMLSRRHTSRLAVLRISLLGRSWLLPPGTL-DQFICLGRAQGLSDDNIV 120 130 140 150 160 170 180 190 pF1KB8 FLPQTDKCMTEQ : XP_006 FPDVTGNMVHLQACWAVGTGPAGMSLVDPRGAGPSVYPGSSAPACAQGSPGSWVPVLNPG 180 190 200 210 220 230 >>XP_011516864 (OMIM: 612905) PREDICTED: epididymal-spec (355 aa) initn: 157 init1: 113 opt: 249 Z-score: 331.5 bits: 69.0 E(85289): 1e-11 Smith-Waterman score: 249; 29.7% identity (61.7% similar) in 175 aa overlap (7-179:7-179) 10 20 30 40 50 60 pF1KB8 MATHHTLWMGLALLGVLGDLQAAPEAQVSVQPNFQQDKFLGRWFSAGLASNSSWLREKKA ::. :.:: :: .: . .:: ..: :.:: :::.:: . :..: XP_011 MRLLCGLWLWLSLLKVLQAQTPTPLPLPPPMQSFQGNQFQGEWFVLGLAGNS-FRPEHRA 10 20 30 40 50 70 80 90 100 110 pF1KB8 ALSMCKSVVAPATDGGLNLTSTFLRKNQCETRTMLLQPAGSLGSYSY-RSPHWGSTYSVS :. .. . :: ... ... : ..:.: ...: ::.. :... .. . :. . XP_011 LLNAFTATFELSDDGRFEVWNAMTRGQHCDTWSYVLIPAAQPGQFTVDHGVEPGADREET 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB8 -VVETDYDQYALLYSQGSKGPGEDFRMATLYSRTQTPRAELKEKFTAFCKAQGFTEDTIV ::..:: :.::. :. . .:.. : : . : ..: . .:::...:.:: XP_011 RVVDSDYTQFALMLSRRHTSRLAVLRISLLGRSWLLPPGTL-DQFICLGRAQGLSDDNIV 120 130 140 150 160 170 180 190 pF1KB8 FLPQTDKCMTEQ : XP_011 FPDVTGNMVHLQACWAVGTGPAGMSLVDPRGAGPSVYPGSSAPACAQGSPGSWVPVLNPG 180 190 200 210 220 230 >>XP_011516862 (OMIM: 612905) PREDICTED: epididymal-spec (382 aa) initn: 157 init1: 113 opt: 249 Z-score: 331.0 bits: 69.0 E(85289): 1.1e-11 Smith-Waterman score: 249; 29.7% identity (61.7% similar) in 175 aa overlap (7-179:34-206) 10 20 30 pF1KB8 MATHHTLWMGLALLGVLGDLQAAPEAQVSVQPNFQQ ::. :.:: :: .: . .:: XP_011 RGGRWTWGPLLPHLAGTQETAAARMRLLCGLWLWLSLLKVLQAQTPTPLPLPPPMQSFQG 10 20 30 40 50 60 40 50 60 70 80 90 pF1KB8 DKFLGRWFSAGLASNSSWLREKKAALSMCKSVVAPATDGGLNLTSTFLRKNQCETRTMLL ..: :.:: :::.:: . :..: :. .. . :: ... ... : ..:.: ...: XP_011 NQFQGEWFVLGLAGNS-FRPEHRALLNAFTATFELSDDGRFEVWNAMTRGQHCDTWSYVL 70 80 90 100 110 120 100 110 120 130 140 150 pF1KB8 QPAGSLGSYSY-RSPHWGSTYSVS-VVETDYDQYALLYSQGSKGPGEDFRMATLYSRTQT ::.. :... .. . :. . ::..:: :.::. :. . .:.. : XP_011 IPAAQPGQFTVDHGVEPGADREETRVVDSDYTQFALMLSRRHTSRLAVLRISLLGRSWLL 130 140 150 160 170 180 160 170 180 190 pF1KB8 PRAELKEKFTAFCKAQGFTEDTIVFLPQTDKCMTEQ : . : ..: . .:::...:.::: XP_011 PPGTL-DQFICLGRAQGLSDDNIVFPDVTGNMVHLQACWAVGTGPAGMSLVDPRGAGPSV 190 200 210 220 230 240 >>XP_011516863 (OMIM: 612905) PREDICTED: epididymal-spec (383 aa) initn: 157 init1: 113 opt: 249 Z-score: 331.0 bits: 69.0 E(85289): 1.1e-11 Smith-Waterman score: 249; 29.7% identity (61.7% similar) in 175 aa overlap (7-179:35-207) 10 20 30 pF1KB8 MATHHTLWMGLALLGVLGDLQAAPEAQVSVQPNFQQ ::. :.:: :: .: . .:: XP_011 RWVSGSPAHGHFLLSVPVGPAAARMRLLCGLWLWLSLLKVLQAQTPTPLPLPPPMQSFQG 10 20 30 40 50 60 40 50 60 70 80 90 pF1KB8 DKFLGRWFSAGLASNSSWLREKKAALSMCKSVVAPATDGGLNLTSTFLRKNQCETRTMLL ..: :.:: :::.:: . :..: :. .. . :: ... ... : ..:.: ...: XP_011 NQFQGEWFVLGLAGNS-FRPEHRALLNAFTATFELSDDGRFEVWNAMTRGQHCDTWSYVL 70 80 90 100 110 120 100 110 120 130 140 150 pF1KB8 QPAGSLGSYSY-RSPHWGSTYSVS-VVETDYDQYALLYSQGSKGPGEDFRMATLYSRTQT ::.. :... .. . :. . ::..:: :.::. :. . .:.. : XP_011 IPAAQPGQFTVDHGVEPGADREETRVVDSDYTQFALMLSRRHTSRLAVLRISLLGRSWLL 130 140 150 160 170 180 160 170 180 190 pF1KB8 PRAELKEKFTAFCKAQGFTEDTIVFLPQTDKCMTEQ : . : ..: . .:::...:.::: XP_011 PPGTL-DQFICLGRAQGLSDDNIVFPDVTGNMVHLQACWAVGTGPAGMSLVDPRGAGPSV 190 200 210 220 230 240 >>XP_016870121 (OMIM: 612905) PREDICTED: epididymal-spec (184 aa) initn: 164 init1: 113 opt: 170 Z-score: 231.2 bits: 49.4 E(85289): 3.9e-06 Smith-Waterman score: 170; 31.0% identity (64.0% similar) in 100 aa overlap (7-106:35-133) 10 20 30 pF1KB8 MATHHTLWMGLALLGVLGDLQAAPEAQVSVQPNFQQ ::. :.:: :: .: . .:: XP_016 RWVSGSPAHGHFLLSVPVGPAAARMRLLCGLWLWLSLLKVLQAQTPTPLPLPPPMQSFQG 10 20 30 40 50 60 40 50 60 70 80 90 pF1KB8 DKFLGRWFSAGLASNSSWLREKKAALSMCKSVVAPATDGGLNLTSTFLRKNQCETRTMLL ..: :.:: :::.:: . :..: :. .. . :: ... ... : ..:.: ...: XP_016 NQFQGEWFVLGLAGNS-FRPEHRALLNAFTATFELSDDGRFEVWNAMTRGQHCDTWSYVL 70 80 90 100 110 120 100 110 120 130 140 150 pF1KB8 QPAGSLGSYSYRSPHWGSTYSVSVVETDYDQYALLYSQGSKGPGEDFRMATLYSRTQTPR ::.. :... XP_016 IPAAQPGQFTVDHGVDTRAGWPSSGSACWAGAGCCLPGRWTSSSAWAELRASRMTTSSSQ 130 140 150 160 170 180 190 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 11:12:10 2016 done: Fri Nov 4 11:12:11 2016 Total Scan time: 5.490 Total Display time: 0.000 Function used was FASTA [36.3.4 Apr, 2011]