FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB8270, 269 aa 1>>>pF1KB8270 269 - 269 aa - 269 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.1785+/-0.000811; mu= 10.1471+/- 0.048 mean_var=84.7180+/-16.653, 0's: 0 Z-trim(108.4): 66 B-trim: 2 in 1/52 Lambda= 0.139343 statistics sampled from 10122 (10187) to 10122 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.691), E-opt: 0.2 (0.313), width: 16 Scan time: 2.250 The best scores are: opt bits E(32554) CCDS12034.1 BSG gene_id:682|Hs108|chr19 ( 269) 1780 367.5 5.6e-102 CCDS12033.1 BSG gene_id:682|Hs108|chr19 ( 385) 1640 339.4 2.2e-93 CCDS12032.1 BSG gene_id:682|Hs108|chr19 ( 205) 1310 273.0 1.2e-73 CCDS58635.1 BSG gene_id:682|Hs108|chr19 ( 176) 1164 243.6 7.3e-65 CCDS10250.1 NPTN gene_id:27020|Hs108|chr15 ( 282) 622 134.7 6.9e-32 CCDS10249.1 NPTN gene_id:27020|Hs108|chr15 ( 398) 612 132.8 3.7e-31 CCDS58379.1 NPTN gene_id:27020|Hs108|chr15 ( 278) 602 130.7 1.1e-30 CCDS58380.1 NPTN gene_id:27020|Hs108|chr15 ( 394) 592 128.7 6e-30 >>CCDS12034.1 BSG gene_id:682|Hs108|chr19 (269 aa) initn: 1780 init1: 1780 opt: 1780 Z-score: 1944.4 bits: 367.5 E(32554): 5.6e-102 Smith-Waterman score: 1780; 100.0% identity (100.0% similar) in 269 aa overlap (1-269:1-269) 10 20 30 40 50 60 pF1KB8 MAAALFVLLGFALLGTHGASGAAGTVFTTVEDLGSKILLTCSLNDSATEVTGHRWLKGGV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS12 MAAALFVLLGFALLGTHGASGAAGTVFTTVEDLGSKILLTCSLNDSATEVTGHRWLKGGV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 VLKEDALPGQKTEFKVDSDDQWGEYSCVFLPEPMGTANIQLHGPPRVKAVKSSEHINEGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS12 VLKEDALPGQKTEFKVDSDDQWGEYSCVFLPEPMGTANIQLHGPPRVKAVKSSEHINEGE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 TAMLVCKSESVPPVTDWAWYKITDSEDKALMNGSESRFFVSSSQGRSELHIENLNMEADP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS12 TAMLVCKSESVPPVTDWAWYKITDSEDKALMNGSESRFFVSSSQGRSELHIENLNMEADP 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 GQYRCNGTSSKGSDQAIITLRVRSHLAALWPFLGIVAEVLVLVTIIFIYEKRRKPEDVLD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS12 GQYRCNGTSSKGSDQAIITLRVRSHLAALWPFLGIVAEVLVLVTIIFIYEKRRKPEDVLD 190 200 210 220 230 240 250 260 pF1KB8 DDDAGSAPLKSSGQHQNDKGKNVRQRNSS ::::::::::::::::::::::::::::: CCDS12 DDDAGSAPLKSSGQHQNDKGKNVRQRNSS 250 260 >>CCDS12033.1 BSG gene_id:682|Hs108|chr19 (385 aa) initn: 1640 init1: 1640 opt: 1640 Z-score: 1789.9 bits: 339.4 E(32554): 2.2e-93 Smith-Waterman score: 1640; 100.0% identity (100.0% similar) in 246 aa overlap (24-269:140-385) 10 20 30 40 50 pF1KB8 MAAALFVLLGFALLGTHGASGAAGTVFTTVEDLGSKILLTCSLNDSATEVTGH :::::::::::::::::::::::::::::: CCDS12 ASNDPDRNHLTRAPRVKWVRAQAVVLVLEPGTVFTTVEDLGSKILLTCSLNDSATEVTGH 110 120 130 140 150 160 60 70 80 90 100 110 pF1KB8 RWLKGGVVLKEDALPGQKTEFKVDSDDQWGEYSCVFLPEPMGTANIQLHGPPRVKAVKSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS12 RWLKGGVVLKEDALPGQKTEFKVDSDDQWGEYSCVFLPEPMGTANIQLHGPPRVKAVKSS 170 180 190 200 210 220 120 130 140 150 160 170 pF1KB8 EHINEGETAMLVCKSESVPPVTDWAWYKITDSEDKALMNGSESRFFVSSSQGRSELHIEN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS12 EHINEGETAMLVCKSESVPPVTDWAWYKITDSEDKALMNGSESRFFVSSSQGRSELHIEN 230 240 250 260 270 280 180 190 200 210 220 230 pF1KB8 LNMEADPGQYRCNGTSSKGSDQAIITLRVRSHLAALWPFLGIVAEVLVLVTIIFIYEKRR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS12 LNMEADPGQYRCNGTSSKGSDQAIITLRVRSHLAALWPFLGIVAEVLVLVTIIFIYEKRR 290 300 310 320 330 340 240 250 260 pF1KB8 KPEDVLDDDDAGSAPLKSSGQHQNDKGKNVRQRNSS :::::::::::::::::::::::::::::::::::: CCDS12 KPEDVLDDDDAGSAPLKSSGQHQNDKGKNVRQRNSS 350 360 370 380 >>CCDS12032.1 BSG gene_id:682|Hs108|chr19 (205 aa) initn: 1307 init1: 1307 opt: 1310 Z-score: 1435.6 bits: 273.0 E(32554): 1.2e-73 Smith-Waterman score: 1310; 95.2% identity (96.6% similar) in 207 aa overlap (63-269:3-205) 40 50 60 70 80 90 pF1KB8 LGSKILLTCSLNDSATEVTGHRWLKGGVVLKEDALPGQKTEFKVDSDDQWGEYSCVFLPE . :: : . .::::::::::::::::: CCDS12 MKQSDASPQE----RVDSDDQWGEYSCVFLPE 10 20 100 110 120 130 140 150 pF1KB8 PMGTANIQLHGPPRVKAVKSSEHINEGETAMLVCKSESVPPVTDWAWYKITDSEDKALMN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS12 PMGTANIQLHGPPRVKAVKSSEHINEGETAMLVCKSESVPPVTDWAWYKITDSEDKALMN 30 40 50 60 70 80 160 170 180 190 200 210 pF1KB8 GSESRFFVSSSQGRSELHIENLNMEADPGQYRCNGTSSKGSDQAIITLRVRSHLAALWPF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS12 GSESRFFVSSSQGRSELHIENLNMEADPGQYRCNGTSSKGSDQAIITLRVRSHLAALWPF 90 100 110 120 130 140 220 230 240 250 260 pF1KB8 LGIVAEVLVLVTIIFIYEKRRKPEDVLDDDDAGSAPLKSSGQHQNDKGKNVRQRNSS ::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS12 LGIVAEVLVLVTIIFIYEKRRKPEDVLDDDDAGSAPLKSSGQHQNDKGKNVRQRNSS 150 160 170 180 190 200 >>CCDS58635.1 BSG gene_id:682|Hs108|chr19 (176 aa) initn: 1164 init1: 1164 opt: 1164 Z-score: 1278.0 bits: 243.6 E(32554): 7.3e-65 Smith-Waterman score: 1164; 100.0% identity (100.0% similar) in 176 aa overlap (94-269:1-176) 70 80 90 100 110 120 pF1KB8 EDALPGQKTEFKVDSDDQWGEYSCVFLPEPMGTANIQLHGPPRVKAVKSSEHINEGETAM :::::::::::::::::::::::::::::: CCDS58 MGTANIQLHGPPRVKAVKSSEHINEGETAM 10 20 30 130 140 150 160 170 180 pF1KB8 LVCKSESVPPVTDWAWYKITDSEDKALMNGSESRFFVSSSQGRSELHIENLNMEADPGQY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 LVCKSESVPPVTDWAWYKITDSEDKALMNGSESRFFVSSSQGRSELHIENLNMEADPGQY 40 50 60 70 80 90 190 200 210 220 230 240 pF1KB8 RCNGTSSKGSDQAIITLRVRSHLAALWPFLGIVAEVLVLVTIIFIYEKRRKPEDVLDDDD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 RCNGTSSKGSDQAIITLRVRSHLAALWPFLGIVAEVLVLVTIIFIYEKRRKPEDVLDDDD 100 110 120 130 140 150 250 260 pF1KB8 AGSAPLKSSGQHQNDKGKNVRQRNSS :::::::::::::::::::::::::: CCDS58 AGSAPLKSSGQHQNDKGKNVRQRNSS 160 170 >>CCDS10250.1 NPTN gene_id:27020|Hs108|chr15 (282 aa) initn: 498 init1: 363 opt: 622 Z-score: 685.9 bits: 134.7 E(32554): 6.9e-32 Smith-Waterman score: 622; 38.1% identity (69.1% similar) in 278 aa overlap (1-269:10-282) 10 20 30 40 pF1KB8 MAAALFVLLGFALLGTHGASGAAGTVFTTVEDL--GSKIL---LTCSLNDS .: .:... : .:: ::. . :. : . : .: : :.:..: CCDS10 MSGSSLPSALALSLLLVSG-SLLPGPGAAQNEPRIVTSEEVIIRDSPVLPVTLQCNLTSS 10 20 30 40 50 50 60 70 80 90 100 pF1KB8 ATEVTGHRWLKGGVVLKEDALPGQKTEFKVDSD--DQWGEYSCV--FLPEPMGTANIQLH . .: : :.:: :. ... :..... .. ::: :: :. : ..:.:... CCDS10 SHTLTYSYWTKNGVELSATRKNASNMEYRINKPRAEDSGEYHCVYHFVSAPKANATIEVK 60 70 80 90 100 110 110 120 130 140 150 160 pF1KB8 GPPRVKAVKSSEHINEGETAMLVCKSESVPPVTDWAWYKITDSEDKALMNGSESRFFVSS . : . . : ::. :::. : . ::: . : :: : : .. ..: : .:::. . CCDS10 AAPDITGHKRSENKNEGQDATMYCKSVGYPH-PDWIWRKKENGMPMDIVNTS-GRFFIIN 120 130 140 150 160 170 170 180 190 200 210 220 pF1KB8 SQGRSELHIENLNMEADPGQYRCNGTSSKGSDQAIITLRVRSHLAALWPFLGIVAEVLVL ... .::.: ::.. :::.:.::.:.. :: ... .:::::::: :::::::.::...: CCDS10 KENYTELNIVNLQITEDPGEYECNATNAIGSASVVTVLRVRSHLAPLWPFLGILAEIIIL 180 190 200 210 220 230 230 240 250 260 pF1KB8 VTIIFIYEKRRKPEDVLDDDDAGSAPLKSSGQHQNDKGKNVRQRNSS :.:: .::::..:..: :::. ..:.:... . : : ::.::::.. CCDS10 VVIIVVYEKRKRPDEVPDDDEP-AGPMKTNSTN-NHKDKNLRQRNTN 240 250 260 270 280 >>CCDS10249.1 NPTN gene_id:27020|Hs108|chr15 (398 aa) initn: 498 init1: 363 opt: 612 Z-score: 672.8 bits: 132.8 E(32554): 3.7e-31 Smith-Waterman score: 612; 40.1% identity (72.2% similar) in 237 aa overlap (37-269:166-398) 10 20 30 40 50 60 pF1KB8 VLLGFALLGTHGASGAAGTVFTTVEDLGSKILLTCSLNDSATEVTGHRWLKGGVVLKEDA . : :.:..:. .: : :.:: :. CCDS10 IRAQATISVLQKPRIVTSEEVIIRDSPVLPVTLQCNLTSSSHTLTYSYWTKNGVELSATR 140 150 160 170 180 190 70 80 90 100 110 120 pF1KB8 LPGQKTEFKVDSD--DQWGEYSCV--FLPEPMGTANIQLHGPPRVKAVKSSEHINEGETA ... :..... .. ::: :: :. : ..:.:.... : . . : ::. :::. : CCDS10 KNASNMEYRINKPRAEDSGEYHCVYHFVSAPKANATIEVKAAPDITGHKRSENKNEGQDA 200 210 220 230 240 250 130 140 150 160 170 180 pF1KB8 MLVCKSESVPPVTDWAWYKITDSEDKALMNGSESRFFVSSSQGRSELHIENLNMEADPGQ . ::: . : :: : : .. ..: : .:::. .... .::.: ::.. :::. CCDS10 TMYCKSVGYPH-PDWIWRKKENGMPMDIVNTS-GRFFIINKENYTELNIVNLQITEDPGE 260 270 280 290 300 310 190 200 210 220 230 240 pF1KB8 YRCNGTSSKGSDQAIITLRVRSHLAALWPFLGIVAEVLVLVTIIFIYEKRRKPEDVLDDD :.::.:.. :: ... .:::::::: :::::::.::...::.:: .::::..:..: ::: CCDS10 YECNATNAIGSASVVTVLRVRSHLAPLWPFLGILAEIIILVVIIVVYEKRKRPDEVPDDD 320 330 340 350 360 370 250 260 pF1KB8 DAGSAPLKSSGQHQNDKGKNVRQRNSS . ..:.:... . : : ::.::::.. CCDS10 EP-AGPMKTNSTN-NHKDKNLRQRNTN 380 390 >>CCDS58379.1 NPTN gene_id:27020|Hs108|chr15 (278 aa) initn: 451 init1: 334 opt: 602 Z-score: 664.3 bits: 130.7 E(32554): 1.1e-30 Smith-Waterman score: 602; 38.1% identity (68.0% similar) in 278 aa overlap (1-269:10-278) 10 20 30 40 pF1KB8 MAAALFVLLGFALLGTHGASGAAGTVFTTVEDL--GSKIL---LTCSLNDS .: .:... : .:: ::. . :. : . : .: : :.:..: CCDS58 MSGSSLPSALALSLLLVSG-SLLPGPGAAQNEPRIVTSEEVIIRDSPVLPVTLQCNLTSS 10 20 30 40 50 50 60 70 80 90 100 pF1KB8 ATEVTGHRWLKGGVVLKEDALPGQKTEFKVDSD--DQWGEYSCV--FLPEPMGTANIQLH . .: : :.:: :. ... :..... .. ::: :: :. : ..:.:... CCDS58 SHTLTYSYWTKNGVELSATRKNASNMEYRINKPRAEDSGEYHCVYHFVSAPKANATIEVK 60 70 80 90 100 110 110 120 130 140 150 160 pF1KB8 GPPRVKAVKSSEHINEGETAMLVCKSESVPPVTDWAWYKITDSEDKALMNGSESRFFVSS . : . . : ::. :::. : . ::: . : :: : : .. ..: : .:::. . CCDS58 AAPDITGHKRSENKNEGQDATMYCKSVGYPH-PDWIWRKKENGMPMDIVNTS-GRFFIIN 120 130 140 150 160 170 170 180 190 200 210 220 pF1KB8 SQGRSELHIENLNMEADPGQYRCNGTSSKGSDQAIITLRVRSHLAALWPFLGIVAEVLVL ... .::.: ::.. :::.:.::.:.. :: ... .:::::::: :::::::.::...: CCDS58 KENYTELNIVNLQITEDPGEYECNATNAIGSASVVTVLRVRSHLAPLWPFLGILAEIIIL 180 190 200 210 220 230 230 240 250 260 pF1KB8 VTIIFIYEKRRKPEDVLDDDDAGSAPLKSSGQHQNDKGKNVRQRNSS :.:: .::::..:..: ::: :.:... . : : ::.::::.. CCDS58 VVIIVVYEKRKRPDEV---PDAG--PMKTNSTN-NHKDKNLRQRNTN 240 250 260 270 >>CCDS58380.1 NPTN gene_id:27020|Hs108|chr15 (394 aa) initn: 451 init1: 334 opt: 592 Z-score: 651.1 bits: 128.7 E(32554): 6e-30 Smith-Waterman score: 592; 40.1% identity (70.9% similar) in 237 aa overlap (37-269:166-394) 10 20 30 40 50 60 pF1KB8 VLLGFALLGTHGASGAAGTVFTTVEDLGSKILLTCSLNDSATEVTGHRWLKGGVVLKEDA . : :.:..:. .: : :.:: :. CCDS58 IRAQATISVLQKPRIVTSEEVIIRDSPVLPVTLQCNLTSSSHTLTYSYWTKNGVELSATR 140 150 160 170 180 190 70 80 90 100 110 120 pF1KB8 LPGQKTEFKVDSD--DQWGEYSCV--FLPEPMGTANIQLHGPPRVKAVKSSEHINEGETA ... :..... .. ::: :: :. : ..:.:.... : . . : ::. :::. : CCDS58 KNASNMEYRINKPRAEDSGEYHCVYHFVSAPKANATIEVKAAPDITGHKRSENKNEGQDA 200 210 220 230 240 250 130 140 150 160 170 180 pF1KB8 MLVCKSESVPPVTDWAWYKITDSEDKALMNGSESRFFVSSSQGRSELHIENLNMEADPGQ . ::: . : :: : : .. ..: : .:::. .... .::.: ::.. :::. CCDS58 TMYCKSVGYPH-PDWIWRKKENGMPMDIVNTS-GRFFIINKENYTELNIVNLQITEDPGE 260 270 280 290 300 310 190 200 210 220 230 240 pF1KB8 YRCNGTSSKGSDQAIITLRVRSHLAALWPFLGIVAEVLVLVTIIFIYEKRRKPEDVLDDD :.::.:.. :: ... .:::::::: :::::::.::...::.:: .::::..:..: CCDS58 YECNATNAIGSASVVTVLRVRSHLAPLWPFLGILAEIIILVVIIVVYEKRKRPDEV---P 320 330 340 350 360 370 250 260 pF1KB8 DAGSAPLKSSGQHQNDKGKNVRQRNSS ::: :.:... . : : ::.::::.. CCDS58 DAG--PMKTNSTN-NHKDKNLRQRNTN 380 390 269 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 11:14:53 2016 done: Fri Nov 4 11:14:54 2016 Total Scan time: 2.250 Total Display time: 0.000 Function used was FASTA [36.3.4 Apr, 2011]