FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB8273, 277 aa 1>>>pF1KB8273 277 - 277 aa - 277 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.4462+/-0.000933; mu= 13.4910+/- 0.055 mean_var=60.4508+/-12.054, 0's: 0 Z-trim(104.6): 28 B-trim: 210 in 1/48 Lambda= 0.164958 statistics sampled from 7979 (8005) to 7979 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.627), E-opt: 0.2 (0.246), width: 16 Scan time: 1.570 The best scores are: opt bits E(32554) CCDS6855.1 PSMB7 gene_id:5695|Hs108|chr9 ( 277) 1801 437.2 6.2e-123 CCDS10853.1 PSMB10 gene_id:5699|Hs108|chr16 ( 273) 1086 267.0 1e-71 CCDS11056.1 PSMB6 gene_id:5694|Hs108|chr17 ( 239) 342 90.0 1.8e-18 CCDS4759.1 PSMB9 gene_id:5698|Hs108|chr6 ( 219) 316 83.8 1.2e-16 CCDS41923.1 PSMB11 gene_id:122706|Hs108|chr14 ( 300) 314 83.3 2.2e-16 CCDS73944.1 PSMB6 gene_id:5694|Hs108|chr17 ( 213) 309 82.1 3.8e-16 CCDS9584.1 PSMB5 gene_id:5693|Hs108|chr14 ( 263) 294 78.5 5.4e-15 CCDS4756.1 PSMB8 gene_id:5696|Hs108|chr6 ( 272) 284 76.2 2.9e-14 CCDS4757.1 PSMB8 gene_id:5696|Hs108|chr6 ( 276) 284 76.2 2.9e-14 >>CCDS6855.1 PSMB7 gene_id:5695|Hs108|chr9 (277 aa) initn: 1801 init1: 1801 opt: 1801 Z-score: 2320.6 bits: 437.2 E(32554): 6.2e-123 Smith-Waterman score: 1801; 100.0% identity (100.0% similar) in 277 aa overlap (1-277:1-277) 10 20 30 40 50 60 pF1KB8 MAAVSVYAPPVGGFSFDNCRRNAVLEADFAKRGYKLPKVRKTGTTIAGVVYKDGIVLGAD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS68 MAAVSVYAPPVGGFSFDNCRRNAVLEADFAKRGYKLPKVRKTGTTIAGVVYKDGIVLGAD 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 TRATEGMVVADKNCSKIHFISPNIYCCGAGTAADTDMTTQLISSNLELHSLSTGRLPRVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS68 TRATEGMVVADKNCSKIHFISPNIYCCGAGTAADTDMTTQLISSNLELHSLSTGRLPRVV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 TANRMLKQMLFRYQGYIGAALVLGGVDVTGPHLYSIYPHGSTDKLPYVTMGSGSLAAMAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS68 TANRMLKQMLFRYQGYIGAALVLGGVDVTGPHLYSIYPHGSTDKLPYVTMGSGSLAAMAV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 FEDKFRPDMEEEEAKNLVSEAIAAGIFNDLGSGSNIDLCVISKNKLDFLRPYTVPNKKGT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS68 FEDKFRPDMEEEEAKNLVSEAIAAGIFNDLGSGSNIDLCVISKNKLDFLRPYTVPNKKGT 190 200 210 220 230 240 250 260 270 pF1KB8 RLGRYRCEKGTTAVLTEKITPLEIEVLEETVQTMDTS ::::::::::::::::::::::::::::::::::::: CCDS68 RLGRYRCEKGTTAVLTEKITPLEIEVLEETVQTMDTS 250 260 270 >>CCDS10853.1 PSMB10 gene_id:5699|Hs108|chr16 (273 aa) initn: 1116 init1: 987 opt: 1086 Z-score: 1401.1 bits: 267.0 E(32554): 1e-71 Smith-Waterman score: 1086; 58.3% identity (86.5% similar) in 266 aa overlap (10-275:8-271) 10 20 30 40 50 60 pF1KB8 MAAVSVYAPPVGGFSFDNCRRNAVLEADFAKRGYKLPKVRKTGTTIAGVVYKDGIVLGAD : :::::.::.::: :: . : :.:..:::::::::.:..::..:::: CCDS10 MLKPALEPRGGFSFENCQRNASLERVLP--GLKVPHARKTGTTIAGLVFQDGVILGAD 10 20 30 40 50 70 80 90 100 110 120 pF1KB8 TRATEGMVVADKNCSKIHFISPNIYCCGAGTAADTDMTTQLISSNLELHSLSTGRLPRVV ::::. :::::.: :::::.:.:::::::.:::..:::....:..:::.::::: :::. CCDS10 TRATNDSVVADKSCEKIHFIAPKIYCCGAGVAADAEMTTRMVASKMELHALSTGREPRVA 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB8 TANRMLKQMLFRYQGYIGAALVLGGVDVTGPHLYSIYPHGSTDKLPYVTMGSGSLAAMAV :..:.:.: ::::::..::.:..::::.:::.::...:::: ..::....:::. ::.:: CCDS10 TVTRILRQTLFRYQGHVGASLIVGGVDLTGPQLYGVHPHGSYSRLPFTALGSGQDAALAV 120 130 140 150 160 170 190 200 210 220 230 240 pF1KB8 FEDKFRPDMEEEEAKNLVSEAIAAGIFNDLGSGSNIDLCVISKNKLDFLRPYTVPNKKGT .::.:.:.: : :..:. ::..:::..:::::.:.: :::.:. .:: . :.. CCDS10 LEDRFQPNMTLEAAQGLLVEAVTAGILGDLGSGGNVDACVITKTGAKLLRTLSSPTEPVK 180 190 200 210 220 230 250 260 270 pF1KB8 RLGRYRCEKGTTAVLTEKITPLEIEVLEETVQTMDTS : :::. :::::::. . :: .:..:::::.:. CCDS10 RSGRYHFVPGTTAVLTQTVKPLTLELVEETVQAMEVE 240 250 260 270 >>CCDS11056.1 PSMB6 gene_id:5694|Hs108|chr17 (239 aa) initn: 336 init1: 259 opt: 342 Z-score: 445.1 bits: 90.0 E(32554): 1.8e-18 Smith-Waterman score: 342; 32.1% identity (65.2% similar) in 187 aa overlap (42-227:33-219) 20 30 40 50 60 70 pF1KB8 GGFSFDNCRRNAVLEADFAKRGYKLPKVRKTGTTIAGVVYKDGIVLGADTRATEGMVVAD ::::: .: . :.:::::.:.: : .:. CCDS11 ATLLAARGAGPAPAWGPEAFTPDWESREVSTGTTIMAVQFDGGVVLGADSRTTTGSYIAN 10 20 30 40 50 60 80 90 100 110 120 130 pF1KB8 KNCSKIHFISPNIYCCGAGTAADTDMTTQLISSNLELHSLSTGRLPRVVTANRMLKQMLF . .:. : :.:: .:.::::. ... .. .: .::. .. : : :: ..:.: . CCDS11 RVTDKLTPIHDRIFCCRSGSAADTQAVADAVTYQLGFHSIELNEPPLVHTAASLFKEMCY 70 80 90 100 110 120 140 150 160 170 180 190 pF1KB8 RYQGYIGAALVLGGVDVT-GPHLYSIYPHGSTDKLPYVTMGSGSLAAMAVFEDKFRPDME ::. . :.....: : : ..::. : . .. :::: .. . .: : CCDS11 RYREDLMAGIIIAGWDPQEGGQVYSVPMGGMMVRQSFAIGGSGSSYIYGYVDATYREGMT 130 140 150 160 170 180 200 210 220 230 240 250 pF1KB8 EEEAKNLVSEAIAAGIFNDLGSGSNIDLCVISKNKLDFLRPYTVPNKKGTRLGRYRCEKG .:: .....:.: .. : .::. : : .:... .. CCDS11 KEECLQFTANALALAMERDGSSGGVIRLAAIAESGVERQVLLGDQIPKFAVATLPPA 190 200 210 220 230 260 270 pF1KB8 TTAVLTEKITPLEIEVLEETVQTMDTS >>CCDS4759.1 PSMB9 gene_id:5698|Hs108|chr6 (219 aa) initn: 326 init1: 302 opt: 316 Z-score: 412.3 bits: 83.8 E(32554): 1.2e-16 Smith-Waterman score: 316; 29.2% identity (64.6% similar) in 195 aa overlap (36-227:11-204) 10 20 30 40 50 60 pF1KB8 VYAPPVGGFSFDNCRRNAVLEADFAKRGYKLPKVRK--TGTTIAGVVYKDGIVLGADTRA ::.. . ::::: .: . :.:.:.:.:. CCDS47 MLRAGAPTGDLPRAGEVHTGTTIMAVEFDGGVVMGSDSRV 10 20 30 40 70 80 90 100 110 120 pF1KB8 TEGMVVADKNCSKIHFISPNIYCCGAGTAADTDMTTQLISSNLELHSLSTGRLPRVVTAN . : .:... .:. . ::: .:.:::.. .... . .::::.. . : :..: CCDS47 SAGEAVVNRVFDKLSPLHERIYCALSGSAADAQAVADMAAYQLELHGIELEEPPLVLAAA 50 60 70 80 90 100 130 140 150 160 170 180 pF1KB8 RMLKQMLFRYQGYIGAALVLGGVDVT-GPHLYSIYPHGSTDKLPYVTMGSGSLAAMAVFE ..... ..:. ..: :...: : : ..:. : . :.. :::: .. . CCDS47 NVVRNISYKYREDLSAHLMVAGWDQREGGQVYGTLG-GMLTRQPFAIGGSGSTFIYGYVD 110 120 130 140 150 190 200 210 220 230 240 pF1KB8 DKFRPDMEEEEAKNLVSEAIAAGIFNDLGSGSNIDLCVISKNKLDFLRPYTVPNKKGTRL ..: : :: . ....::: .. : .::. : : .:. .: CCDS47 AAYKPGMSPEECRRFTTDAIALAMSRDGSSGGVIYLVTITAAGVDHRVILGNELPKFYDE 160 170 180 190 200 210 250 260 270 pF1KB8 GRYRCEKGTTAVLTEKITPLEIEVLEETVQTMDTS >>CCDS41923.1 PSMB11 gene_id:122706|Hs108|chr14 (300 aa) initn: 312 init1: 166 opt: 314 Z-score: 407.5 bits: 83.3 E(32554): 2.2e-16 Smith-Waterman score: 314; 29.6% identity (59.3% similar) in 216 aa overlap (5-218:18-225) 10 20 30 40 pF1KB8 MAAVSVYAPPVGGFSFD-NCRRNAVLEADFAKRGYKLPKVRKTGTTI : . : .::.. .: .. :. .: .: . ::: CCDS41 MALQDVCKWQSPDTQGPSPHLPRAGGWAVPRGCDPQTFLQI----HGPRLAH----GTTT 10 20 30 40 50 50 60 70 80 90 100 pF1KB8 AGVVYKDGIVLGADTRATEGMVVADKNCSKIHFISPNIYCCGAGTAADTDMTTQLISSNL . .. :.. .::::.. : :: :. . .. .::.:: .... .: CCDS41 LAFRFRHGVIAAADTRSSCGSYVACPASCKVIPVHQHLLGTTSGTSADCATWYRVLQREL 60 70 80 90 100 110 110 120 130 140 150 160 pF1KB8 ELHSLSTGRLPRVVTANRMLKQMLFRYQGY-IGAALVLGGVDVTGPHLYSIYPHGSTDKL .:. : :.:: :..: ..:. :. .:.: . .: .: : : .::.:. .: :. . CCDS41 RLRELREGQLPSVASAAKLLSAMMSQYRGLDLCVATALCGWDRSGPELFYVYSDGTRLQG 120 130 140 150 160 170 170 180 190 200 210 220 pF1KB8 PYVTMGSGSLAAMAVFEDKFRPDMEEEEAKNLVSEAIAAGIFNDLGSGSNIDLCVISKNK ..:::: :..:.. .: :: .:: :. :.: . : ::...:: CCDS41 DIFSVGSGSPYAYGVLDRGYRYDMSTQEAYALARCAVAHATHRDAYSGGSVDLFHVRESG 180 190 200 210 220 230 230 240 250 260 270 pF1KB8 LDFLRPYTVPNKKGTRLGRYRCEKGTTAVLTEKITPLEIEVLEETVQTMDTS CCDS41 WEHVSRSDACVLYVELQKLLEPEPEEDASHAHPEPATAHRAAEDRELSVGPGEVTPGDSR 240 250 260 270 280 290 >>CCDS73944.1 PSMB6 gene_id:5694|Hs108|chr17 (213 aa) initn: 284 init1: 240 opt: 309 Z-score: 403.5 bits: 82.1 E(32554): 3.8e-16 Smith-Waterman score: 309; 32.9% identity (64.6% similar) in 161 aa overlap (42-201:33-193) 20 30 40 50 60 70 pF1KB8 GGFSFDNCRRNAVLEADFAKRGYKLPKVRKTGTTIAGVVYKDGIVLGADTRATEGMVVAD ::::: .: . :.:::::.:.: : .:. CCDS73 ATLLAARGAGPAPAWGPEAFTPDWESREVSTGTTIMAVQFDGGVVLGADSRTTTGSYIAN 10 20 30 40 50 60 80 90 100 110 120 130 pF1KB8 KNCSKIHFISPNIYCCGAGTAADTDMTTQLISSNLELHSLSTGRLPRVVTANRMLKQMLF . .:. : :.:: .:.::::. ... .. .: .::. .. : : :: ..:.: . CCDS73 RVTDKLTPIHDRIFCCRSGSAADTQAVADAVTYQLGFHSIELNEPPLVHTAASLFKEMCY 70 80 90 100 110 120 140 150 160 170 180 190 pF1KB8 RYQGYIGAALVLGGVDVT-GPHLYSIYPHGSTDKLPYVTMGSGSLAAMAVFEDKFRPDME ::. . :.....: : : ..::. : . .. :::: .. . .: : CCDS73 RYREDLMAGIIIAGWDPQEGGQVYSVPMGGMMVRQSFAIGGSGSSYIYGYVDATYREGMT 130 140 150 160 170 180 200 210 220 230 240 250 pF1KB8 EEEAKNLVSEAIAAGIFNDLGSGSNIDLCVISKNKLDFLRPYTVPNKKGTRLGRYRCEKG .:: .....: CCDS73 KEECLQFTANAFFFYPQLSLWPWSGMAPVEE 190 200 210 >>CCDS9584.1 PSMB5 gene_id:5693|Hs108|chr14 (263 aa) initn: 232 init1: 125 opt: 294 Z-score: 382.7 bits: 78.5 E(32554): 5.4e-15 Smith-Waterman score: 294; 28.8% identity (65.5% similar) in 177 aa overlap (43-218:59-235) 20 30 40 50 60 70 pF1KB8 GFSFDNCRRNAVLEADFAKRGYKLPKVRKTGTTIAGVVYKDGIVLGADTRATEGMVVADK ::: . .. :....::.::: : .:.. CCDS95 DLGPGSLSDGLSLAAPGWGVPEEPGIEMLHGTTTLAFKFRHGVIVAADSRATAGAYIASQ 30 40 50 60 70 80 80 90 100 110 120 130 pF1KB8 NCSKIHFISPNIYCCGAGTAADTDMTTQLISSNLELHSLSTGRLPRVVTANRMLKQMLFR . .:. :.: . :: ::: .. .:.. . ... : . . :..:...: .:... CCDS95 TVKKVIEINPYLLGTMAGGAADCSFWERLLARQCRIYELRNKERISVAAASKLLANMVYQ 90 100 110 120 130 140 140 150 160 170 180 190 pF1KB8 YQGY-IGAALVLGGVDVTGPHLYSIYPHGSTDKLPYVTMGSGSLAAMAVFEDKFRPDMEE :.:. .. . .. : : :: :: . .:. . ..::::. :..:.. . :.: CCDS95 YKGMGLSMGTMICGWDKRGPGLYYVDSEGNRISGATFSVGSGSVYAYGVMDRGYSYDLEV 150 160 170 180 190 200 200 210 220 230 240 250 pF1KB8 EEAKNLVSEAIAAGIFNDLGSGSNIDLCVISKNKLDFLRPYTVPNKKGTRLGRYRCEKGT :.: .:. .:: . . : ::. ..: CCDS95 EQAYDLARRAIYQATYRDAYSGGAVNLYHVREDGWIRVSSDNVADLHEKYSGSTP 210 220 230 240 250 260 >>CCDS4756.1 PSMB8 gene_id:5696|Hs108|chr6 (272 aa) initn: 240 init1: 137 opt: 284 Z-score: 369.6 bits: 76.2 E(32554): 2.9e-14 Smith-Waterman score: 284; 28.7% identity (63.5% similar) in 178 aa overlap (43-218:68-244) 20 30 40 50 60 70 pF1KB8 GFSFDNCRRNAVLEADFAKRGYKLPKVRKTGTTIAGVVYKDGIVLGADTRATEGMVVADK ::: . .. :.. ..:.::. : .. CCDS47 SSGCPGLEPTEFFQSLGGDGERNVQIEMAHGTTTLAFKFQHGVIAAVDSRASAGSYISAL 40 50 60 70 80 90 80 90 100 110 120 130 pF1KB8 NCSKIHFISPNIYCCGAGTAADTDMTTQLISSNLELHSLSTGRLPRVVTANRMLKQMLFR .:. :.: . .: ::: .. .:.... .:. : .:. : .:...:..:. . CCDS47 RVNKVIEINPYLLGTMSGCAADCQYWERLLAKECRLYYLRNGERISVSAASKLLSNMMCQ 100 110 120 130 140 150 140 150 160 170 180 190 pF1KB8 YQGYIGAAL--VLGGVDVTGPHLYSIYPHGSTDKLPYVTMGSGSLAAMAVFEDKFRPDME :.: .: .. .. : : :: :: . ::. . . . :::. :..:... .::.. CCDS47 YRG-MGLSMGSMICGWDKKGPGLYYVDEHGTRLSGNMFSTGSGNTYAYGVMDSGYRPNLS 160 170 180 190 200 210 200 210 220 230 240 250 pF1KB8 EEEAKNLVSEAIAAGIFNDLGSGSNIDLCVISKNKLDFLRPYTVPNKKGTRLGRYRCEKG ::: .: .::: . : ::. ... CCDS47 PEEAYDLGRRAIAYATHRDSYSGGVVNMYHMKEDGWVKVESTDVSDLLHQYREANQ 220 230 240 250 260 270 >>CCDS4757.1 PSMB8 gene_id:5696|Hs108|chr6 (276 aa) initn: 217 init1: 137 opt: 284 Z-score: 369.5 bits: 76.2 E(32554): 2.9e-14 Smith-Waterman score: 284; 28.7% identity (63.5% similar) in 178 aa overlap (43-218:72-248) 20 30 40 50 60 70 pF1KB8 GFSFDNCRRNAVLEADFAKRGYKLPKVRKTGTTIAGVVYKDGIVLGADTRATEGMVVADK ::: . .. :.. ..:.::. : .. CCDS47 LALPRGMQPTEFFQSLGGDGERNVQIEMAHGTTTLAFKFQHGVIAAVDSRASAGSYISAL 50 60 70 80 90 100 80 90 100 110 120 130 pF1KB8 NCSKIHFISPNIYCCGAGTAADTDMTTQLISSNLELHSLSTGRLPRVVTANRMLKQMLFR .:. :.: . .: ::: .. .:.... .:. : .:. : .:...:..:. . CCDS47 RVNKVIEINPYLLGTMSGCAADCQYWERLLAKECRLYYLRNGERISVSAASKLLSNMMCQ 110 120 130 140 150 160 140 150 160 170 180 190 pF1KB8 YQGYIGAAL--VLGGVDVTGPHLYSIYPHGSTDKLPYVTMGSGSLAAMAVFEDKFRPDME :.: .: .. .. : : :: :: . ::. . . . :::. :..:... .::.. CCDS47 YRG-MGLSMGSMICGWDKKGPGLYYVDEHGTRLSGNMFSTGSGNTYAYGVMDSGYRPNLS 170 180 190 200 210 220 200 210 220 230 240 250 pF1KB8 EEEAKNLVSEAIAAGIFNDLGSGSNIDLCVISKNKLDFLRPYTVPNKKGTRLGRYRCEKG ::: .: .::: . : ::. ... CCDS47 PEEAYDLGRRAIAYATHRDSYSGGVVNMYHMKEDGWVKVESTDVSDLLHQYREANQ 230 240 250 260 270 277 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 11:17:20 2016 done: Fri Nov 4 11:17:20 2016 Total Scan time: 1.570 Total Display time: -0.010 Function used was FASTA [36.3.4 Apr, 2011]