Result of FASTA (omim) for pF1KB8275
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB8275, 306 aa
  1>>>pF1KB8275 306 - 306 aa - 306 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 6.6529+/-0.000443; mu= 13.6149+/- 0.028
 mean_var=279.4367+/-62.180, 0's: 0 Z-trim(118.8): 164  B-trim: 1880 in 1/55
 Lambda= 0.076724
 statistics sampled from 31864 (32098) to 31864 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.72), E-opt: 0.2 (0.376), width:  16
 Scan time:  7.260

The best scores are:                                      opt bits E(85289)
NP_002129 (OMIM: 601324) heterogeneous nuclear rib ( 306) 2042 239.1 8.6e-63
NP_112738 (OMIM: 601324) heterogeneous nuclear rib ( 355) 1887 222.0 1.4e-57
NP_001003810 (OMIM: 601324) heterogeneous nuclear  ( 287) 1487 177.6 2.6e-44
NP_112737 (OMIM: 601324) heterogeneous nuclear rib ( 336) 1332 160.5 4.1e-39
NP_001193929 (OMIM: 607137,609115) heterogeneous n ( 363) 1071 131.7 2.1e-30
NP_004490 (OMIM: 602688) heterogeneous nuclear rib ( 285) 1065 130.9   3e-30
NP_112556 (OMIM: 602688) heterogeneous nuclear rib ( 332)  988 122.5 1.2e-27
NP_112740 (OMIM: 607137,609115) heterogeneous nucl ( 420)  988 122.6 1.3e-27
NP_001317180 (OMIM: 605372) heterogeneous nuclear  ( 331)  606 80.2 6.4e-15
NP_001317179 (OMIM: 605372) heterogeneous nuclear  ( 331)  606 80.2 6.4e-15
NP_919223 (OMIM: 605372) heterogeneous nuclear rib ( 378)  606 80.3 6.8e-15
NP_001317178 (OMIM: 605372) heterogeneous nuclear  ( 378)  606 80.3 6.8e-15
NP_001317177 (OMIM: 605372) heterogeneous nuclear  ( 356)  600 79.6   1e-14
NP_001317176 (OMIM: 605372) heterogeneous nuclear  ( 356)  600 79.6   1e-14
NP_002128 (OMIM: 600124,615422) heterogeneous nucl ( 341)  576 76.9 6.4e-14
XP_016867598 (OMIM: 600124,615422) PREDICTED: hete ( 341)  576 76.9 6.4e-14
XP_016867599 (OMIM: 600124,615422) PREDICTED: hete ( 341)  576 76.9 6.4e-14
NP_112533 (OMIM: 600124,615422) heterogeneous nucl ( 353)  576 76.9 6.6e-14
XP_005249786 (OMIM: 600124,615422) PREDICTED: hete ( 353)  576 76.9 6.6e-14
XP_016874740 (OMIM: 164017,615424,615426) PREDICTE ( 295)  557 74.7 2.6e-13
NP_002127 (OMIM: 164017,615424,615426) heterogeneo ( 320)  557 74.7 2.7e-13
XP_005268883 (OMIM: 164017,615424,615426) PREDICTE ( 372)  557 74.8 2.9e-13
NP_112420 (OMIM: 164017,615424,615426) heterogeneo ( 372)  557 74.8 2.9e-13
NP_001309180 (OMIM: 607897) RNA-binding protein Mu ( 255)  552 74.0 3.5e-13
XP_016879637 (OMIM: 607897) PREDICTED: RNA-binding ( 295)  552 74.1 3.8e-13
NP_620412 (OMIM: 607897) RNA-binding protein Musas ( 328)  552 74.2   4e-13
XP_005257072 (OMIM: 607897) PREDICTED: RNA-binding ( 346)  552 74.2 4.1e-13
XP_005257071 (OMIM: 607897) PREDICTED: RNA-binding ( 346)  552 74.2 4.1e-13
NP_733839 (OMIM: 607897) RNA-binding protein Musas ( 251)  542 72.9 7.5e-13
NP_001309179 (OMIM: 607897) RNA-binding protein Mu ( 324)  536 72.4 1.4e-12
XP_011536665 (OMIM: 603328) PREDICTED: RNA-binding ( 332)  523 71.0 3.7e-12
XP_011536664 (OMIM: 603328) PREDICTED: RNA-binding ( 343)  523 71.0 3.8e-12
XP_006719466 (OMIM: 603328) PREDICTED: RNA-binding ( 351)  523 71.0 3.8e-12
NP_002433 (OMIM: 603328) RNA-binding protein Musas ( 362)  523 71.0 3.9e-12
XP_011536663 (OMIM: 603328) PREDICTED: RNA-binding ( 362)  523 71.0 3.9e-12
NP_006796 (OMIM: 609409) heterogeneous nuclear rib ( 305)  471 65.2 1.9e-10
XP_016856353 (OMIM: 605078,612069) PREDICTED: TAR  ( 414)  386 56.0 1.5e-07
XP_016856357 (OMIM: 605078,612069) PREDICTED: TAR  ( 414)  386 56.0 1.5e-07
XP_016856354 (OMIM: 605078,612069) PREDICTED: TAR  ( 414)  386 56.0 1.5e-07
XP_016856352 (OMIM: 605078,612069) PREDICTED: TAR  ( 414)  386 56.0 1.5e-07
XP_016856356 (OMIM: 605078,612069) PREDICTED: TAR  ( 414)  386 56.0 1.5e-07
NP_031401 (OMIM: 605078,612069) TAR DNA-binding pr ( 414)  386 56.0 1.5e-07
XP_016856355 (OMIM: 605078,612069) PREDICTED: TAR  ( 414)  386 56.0 1.5e-07
XP_016879636 (OMIM: 607897) PREDICTED: RNA-binding ( 315)  334 50.0 7.2e-06
XP_016882071 (OMIM: 607430) PREDICTED: DAZ-associa ( 327)  290 45.2 0.00021
XP_011526209 (OMIM: 607430) PREDICTED: DAZ-associa ( 548)  293 45.9 0.00022
XP_011526208 (OMIM: 607430) PREDICTED: DAZ-associa ( 549)  293 45.9 0.00022
XP_005259588 (OMIM: 607430) PREDICTED: DAZ-associa ( 406)  290 45.3 0.00024
XP_011526210 (OMIM: 607430) PREDICTED: DAZ-associa ( 521)  290 45.5 0.00027
XP_011526211 (OMIM: 607430) PREDICTED: DAZ-associa ( 521)  290 45.5 0.00027


>>NP_002129 (OMIM: 601324) heterogeneous nuclear ribonuc  (306 aa)
 initn: 2042 init1: 2042 opt: 2042  Z-score: 1248.3  bits: 239.1 E(85289): 8.6e-63
Smith-Waterman score: 2042; 100.0% identity (100.0% similar) in 306 aa overlap (1-306:1-306)

               10        20        30        40        50        60
pF1KB8 MSEEQFGGDGAAAAATAAVGGSAGEQEGAMVAATQGAAAAAGSGAGTGGGTASGGTEGGS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 MSEEQFGGDGAAAAATAAVGGSAGEQEGAMVAATQGAAAAAGSGAGTGGGTASGGTEGGS
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB8 AESEGAKIDASKNEEDEGHSNSSPRHSEAATAQREEWKMFIGGLSWDTTKKDLKDYFSKF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 AESEGAKIDASKNEEDEGHSNSSPRHSEAATAQREEWKMFIGGLSWDTTKKDLKDYFSKF
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB8 GEVVDCTLKLDPITGRSRGFGFVLFKESESVDKVMDQKEHKLNGKVIDPKRAKAMKTKEP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 GEVVDCTLKLDPITGRSRGFGFVLFKESESVDKVMDQKEHKLNGKVIDPKRAKAMKTKEP
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB8 VKKIFVGGLSPDTPEEKIREYFGGFGEVESIELPMDNKTNKRRGFCFITFKEEEPVKKIM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 VKKIFVGGLSPDTPEEKIREYFGGFGEVESIELPMDNKTNKRRGFCFITFKEEEPVKKIM
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB8 EKKYHNVGLSKCEIKVAMSKEQYQQQQQWGSRGGFAGRARGRGGDQQSGYGKVSRRGGHQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 EKKYHNVGLSKCEIKVAMSKEQYQQQQQWGSRGGFAGRARGRGGDQQSGYGKVSRRGGHQ
              250       260       270       280       290       300

             
pF1KB8 NSYKPY
       ::::::
NP_002 NSYKPY
             

>>NP_112738 (OMIM: 601324) heterogeneous nuclear ribonuc  (355 aa)
 initn: 2309 init1: 1886 opt: 1887  Z-score: 1154.9  bits: 222.0 E(85289): 1.4e-57
Smith-Waterman score: 1887; 93.8% identity (96.4% similar) in 307 aa overlap (1-303:1-307)

               10        20        30        40        50        60
pF1KB8 MSEEQFGGDGAAAAATAAVGGSAGEQEGAMVAATQGAAAAAGSGAGTGGGTASGGTEGGS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_112 MSEEQFGGDGAAAAATAAVGGSAGEQEGAMVAATQGAAAAAGSGAGTGGGTASGGTEGGS
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB8 AESEGAKIDASKNEEDEGHSNSSPRHSEAATAQREEWKMFIGGLSWDTTKKDLKDYFSKF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_112 AESEGAKIDASKNEEDEGHSNSSPRHSEAATAQREEWKMFIGGLSWDTTKKDLKDYFSKF
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB8 GEVVDCTLKLDPITGRSRGFGFVLFKESESVDKVMDQKEHKLNGKVIDPKRAKAMKTKEP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_112 GEVVDCTLKLDPITGRSRGFGFVLFKESESVDKVMDQKEHKLNGKVIDPKRAKAMKTKEP
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB8 VKKIFVGGLSPDTPEEKIREYFGGFGEVESIELPMDNKTNKRRGFCFITFKEEEPVKKIM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_112 VKKIFVGGLSPDTPEEKIREYFGGFGEVESIELPMDNKTNKRRGFCFITFKEEEPVKKIM
              190       200       210       220       230       240

              250       260       270       280           290      
pF1KB8 EKKYHNVGLSKCEIKVAMSKEQYQQQQQWGSRGGFAGRARGRGG----DQQSGYGKVSRR
       ::::::::::::::::::::::::::::::::::::::::::::    . ..::..   .
NP_112 EKKYHNVGLSKCEIKVAMSKEQYQQQQQWGSRGGFAGRARGRGGGPSQNWNQGYSNYWNQ
              250       260       270       280       290       300

        300                                                   
pF1KB8 GGHQNSYKPY                                             
       :  . .:                                                
NP_112 GYGNYGYNSQGYGGYGGYDYTGYNNYYGYGDYSNQQSGYGKVSRRGGHQNSYKPY
              310       320       330       340       350     

>>NP_001003810 (OMIM: 601324) heterogeneous nuclear ribo  (287 aa)
 initn: 1438 init1: 1438 opt: 1487  Z-score: 916.5  bits: 177.6 E(85289): 2.6e-44
Smith-Waterman score: 1863; 93.8% identity (93.8% similar) in 306 aa overlap (1-306:1-287)

               10        20        30        40        50        60
pF1KB8 MSEEQFGGDGAAAAATAAVGGSAGEQEGAMVAATQGAAAAAGSGAGTGGGTASGGTEGGS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MSEEQFGGDGAAAAATAAVGGSAGEQEGAMVAATQGAAAAAGSGAGTGGGTASGGTEGGS
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB8 AESEGAKIDASKNEEDEGHSNSSPRHSEAATAQREEWKMFIGGLSWDTTKKDLKDYFSKF
       ::::::::::::::::::                   :::::::::::::::::::::::
NP_001 AESEGAKIDASKNEEDEG-------------------KMFIGGLSWDTTKKDLKDYFSKF
               70                           80        90       100 

              130       140       150       160       170       180
pF1KB8 GEVVDCTLKLDPITGRSRGFGFVLFKESESVDKVMDQKEHKLNGKVIDPKRAKAMKTKEP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GEVVDCTLKLDPITGRSRGFGFVLFKESESVDKVMDQKEHKLNGKVIDPKRAKAMKTKEP
             110       120       130       140       150       160 

              190       200       210       220       230       240
pF1KB8 VKKIFVGGLSPDTPEEKIREYFGGFGEVESIELPMDNKTNKRRGFCFITFKEEEPVKKIM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VKKIFVGGLSPDTPEEKIREYFGGFGEVESIELPMDNKTNKRRGFCFITFKEEEPVKKIM
             170       180       190       200       210       220 

              250       260       270       280       290       300
pF1KB8 EKKYHNVGLSKCEIKVAMSKEQYQQQQQWGSRGGFAGRARGRGGDQQSGYGKVSRRGGHQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EKKYHNVGLSKCEIKVAMSKEQYQQQQQWGSRGGFAGRARGRGGDQQSGYGKVSRRGGHQ
             230       240       250       260       270       280 

             
pF1KB8 NSYKPY
       ::::::
NP_001 NSYKPY
             

>>NP_112737 (OMIM: 601324) heterogeneous nuclear ribonuc  (336 aa)
 initn: 2054 init1: 1269 opt: 1332  Z-score: 823.1  bits: 160.5 E(85289): 4.1e-39
Smith-Waterman score: 1708; 87.6% identity (90.2% similar) in 307 aa overlap (1-303:1-288)

               10        20        30        40        50        60
pF1KB8 MSEEQFGGDGAAAAATAAVGGSAGEQEGAMVAATQGAAAAAGSGAGTGGGTASGGTEGGS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_112 MSEEQFGGDGAAAAATAAVGGSAGEQEGAMVAATQGAAAAAGSGAGTGGGTASGGTEGGS
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB8 AESEGAKIDASKNEEDEGHSNSSPRHSEAATAQREEWKMFIGGLSWDTTKKDLKDYFSKF
       ::::::::::::::::::                   :::::::::::::::::::::::
NP_112 AESEGAKIDASKNEEDEG-------------------KMFIGGLSWDTTKKDLKDYFSKF
               70                           80        90       100 

              130       140       150       160       170       180
pF1KB8 GEVVDCTLKLDPITGRSRGFGFVLFKESESVDKVMDQKEHKLNGKVIDPKRAKAMKTKEP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_112 GEVVDCTLKLDPITGRSRGFGFVLFKESESVDKVMDQKEHKLNGKVIDPKRAKAMKTKEP
             110       120       130       140       150       160 

              190       200       210       220       230       240
pF1KB8 VKKIFVGGLSPDTPEEKIREYFGGFGEVESIELPMDNKTNKRRGFCFITFKEEEPVKKIM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_112 VKKIFVGGLSPDTPEEKIREYFGGFGEVESIELPMDNKTNKRRGFCFITFKEEEPVKKIM
             170       180       190       200       210       220 

              250       260       270       280           290      
pF1KB8 EKKYHNVGLSKCEIKVAMSKEQYQQQQQWGSRGGFAGRARGRGG----DQQSGYGKVSRR
       ::::::::::::::::::::::::::::::::::::::::::::    . ..::..   .
NP_112 EKKYHNVGLSKCEIKVAMSKEQYQQQQQWGSRGGFAGRARGRGGGPSQNWNQGYSNYWNQ
             230       240       250       260       270       280 

        300                                                   
pF1KB8 GGHQNSYKPY                                             
       :  . .:                                                
NP_112 GYGNYGYNSQGYGGYGGYDYTGYNNYYGYGDYSNQQSGYGKVSRRGGHQNSYKPY
             290       300       310       320       330      

>>NP_001193929 (OMIM: 607137,609115) heterogeneous nucle  (363 aa)
 initn: 1145 init1: 934 opt: 1071  Z-score: 666.7  bits: 131.7 E(85289): 2.1e-30
Smith-Waterman score: 1081; 65.6% identity (82.8% similar) in 250 aa overlap (63-306:133-363)

             40        50        60        70        80        90  
pF1KB8 ATQGAAAAAGSGAGTGGGTASGGTEGGSAESEGAKIDASKNEEDEGHSNSSPRHSEAATA
                                     .::.::.::::..:.:              
NP_001 AATRTARQHPPADSSVTMEDMNEYSNIEEFAEGSKINASKNQQDDG--------------
            110       120       130       140                      

            100       110       120       130       140       150  
pF1KB8 QREEWKMFIGGLSWDTTKKDLKDYFSKFGEVVDCTLKLDPITGRSRGFGFVLFKESESVD
            :::::::::::.:::: .:.:.::::::::.: ::.:::::::::::::.. :::
NP_001 -----KMFIGGLSWDTSKKDLTEYLSRFGEVVDCTIKTDPVTGRSRGFGFVLFKDAASVD
           150       160       170       180       190       200   

            160       170       180       190       200       210  
pF1KB8 KVMDQKEHKLNGKVIDPKRAKAMKTKEPVKKIFVGGLSPDTPEEKIREYFGGFGEVESIE
       ::.. :::::.::.::::::::.: ::: ::.::::::::: ::.:.::::.:::.:.::
NP_001 KVLELKEHKLDGKLIDPKRAKALKGKEPPKKVFVGGLSPDTSEEQIKEYFGAFGEIENIE
           210       220       230       240       250       260   

            220       230       240       250       260         270
pF1KB8 LPMDNKTNKRRGFCFITFKEEEPVKKIMEKKYHNVGLSKCEIKVAMSKEQY--QQQQQWG
       ::::.:::.::::::::. .::::::..:..::..: .:::::::. :: :  ::::: :
NP_001 LPMDTKTNERRGFCFITYTDEEPVKKLLESRYHQIGSGKCEIKVAQPKEVYRQQQQQQKG
           270       280       290       300       310       320   

                 280       290        300      
pF1KB8 SRGGFAGR---ARGRGGDQQSGYGKVSRRGG-HQNSYKPY
       .::. ::    .::::  ::: :::.:: :: :::.:.::
NP_001 GRGAAAGGRGGTRGRGRGQQSTYGKASRGGGNHQNNYQPY
           330       340       350       360   

>>NP_004490 (OMIM: 602688) heterogeneous nuclear ribonuc  (285 aa)
 initn: 1075 init1: 474 opt: 1065  Z-score: 664.1  bits: 130.9 E(85289): 3e-30
Smith-Waterman score: 1124; 60.5% identity (79.4% similar) in 296 aa overlap (22-306:12-285)

               10        20        30         40        50         
pF1KB8 MSEEQFGGDGAAAAATAAVGGSAGEQEGAMVAATQGAA-AAAGSGAGTGGGTASGGTEGG
                            ..:  :..  :. .: . :.::.::..:.: :...  .:
NP_004           MSEAGEEQPMETTGATENGHEAVPEGESPAGAGTGAAAGAGGATAAPPSG
                         10        20        30        40        50

      60         70        80        90       100       110        
pF1KB8 SAE-SEGAKIDASKNEEDEGHSNSSPRHSEAATAQREEWKMFIGGLSWDTTKKDLKDYFS
       . . .:: .:.::::::: :                   :::.:::::::.::::::::.
NP_004 NQNGAEGDQINASKNEEDAG-------------------KMFVGGLSWDTSKKDLKDYFT
               60        70                           80        90 

      120       130       140       150       160       170        
pF1KB8 KFGEVVDCTLKLDPITGRSRGFGFVLFKESESVDKVMDQKEHKLNGKVIDPKRAKAMKTK
       :::::::::.:.:: :::::::::.:::.. ::.::.:::::.:.:.:::::.: ::: :
NP_004 KFGEVVDCTIKMDPNTGRSRGFGFILFKDAASVEKVLDQKEHRLDGRVIDPKKAMAMK-K
             100       110       120       130       140        150

      180       190       200       210       220       230        
pF1KB8 EPVKKIFVGGLSPDTPEEKIREYFGGFGEVESIELPMDNKTNKRRGFCFITFKEEEPVKK
       .::::::::::.:.. ::::::::: :::.:.:::::: : :::::: ::::::::::::
NP_004 DPVKKIFVGGLNPEATEEKIREYFGEFGEIEAIELPMDPKLNKRRGFVFITFKEEEPVKK
              160       170       180       190       200       210

      240       250       260       270       280                  
pF1KB8 IMEKKYHNVGLSKCEIKVAMSKEQYQQQQQWGSRGGFAGRARGR---------GGDQQSG
       ..:::.:.:. ::::::::. :: ::::: .:: :: ..: ::          ::. ...
NP_004 VLEKKFHTVSGSKCEIKVAQPKEVYQQQQ-YGS-GGRGNRNRGNRGSGGGGGGGGQGSTN
              220       230        240        250       260        

     290       300      
pF1KB8 YGKVSRRGGHQNSYKPY
       ::: .:::::::.::::
NP_004 YGKSQRRGGHQNNYKPY
      270       280     

>>NP_112556 (OMIM: 602688) heterogeneous nuclear ribonuc  (332 aa)
 initn: 1105 init1: 474 opt: 988  Z-score: 617.4  bits: 122.5 E(85289): 1.2e-27
Smith-Waterman score: 1061; 58.5% identity (77.6% similar) in 299 aa overlap (22-305:12-288)

               10        20        30         40        50         
pF1KB8 MSEEQFGGDGAAAAATAAVGGSAGEQEGAMVAATQGAA-AAAGSGAGTGGGTASGGTEGG
                            ..:  :..  :. .: . :.::.::..:.: :...  .:
NP_112           MSEAGEEQPMETTGATENGHEAVPEGESPAGAGTGAAAGAGGATAAPPSG
                         10        20        30        40        50

      60         70        80        90       100       110        
pF1KB8 SAE-SEGAKIDASKNEEDEGHSNSSPRHSEAATAQREEWKMFIGGLSWDTTKKDLKDYFS
       . . .:: .:.::::::: :                   :::.:::::::.::::::::.
NP_112 NQNGAEGDQINASKNEEDAG-------------------KMFVGGLSWDTSKKDLKDYFT
               60        70                           80        90 

      120       130       140       150       160       170        
pF1KB8 KFGEVVDCTLKLDPITGRSRGFGFVLFKESESVDKVMDQKEHKLNGKVIDPKRAKAMKTK
       :::::::::.:.:: :::::::::.:::.. ::.::.:::::.:.:.:::::.: ::: :
NP_112 KFGEVVDCTIKMDPNTGRSRGFGFILFKDAASVEKVLDQKEHRLDGRVIDPKKAMAMK-K
             100       110       120       130       140        150

      180       190       200       210       220       230        
pF1KB8 EPVKKIFVGGLSPDTPEEKIREYFGGFGEVESIELPMDNKTNKRRGFCFITFKEEEPVKK
       .::::::::::.:.. ::::::::: :::.:.:::::: : :::::: ::::::::::::
NP_112 DPVKKIFVGGLNPEATEEKIREYFGEFGEIEAIELPMDPKLNKRRGFVFITFKEEEPVKK
              160       170       180       190       200       210

      240       250       260       270       280                  
pF1KB8 IMEKKYHNVGLSKCEIKVAMSKEQYQQQQQWGSRGGFAGRARGR---------GGDQQS-
       ..:::.:.:. ::::::::. :: ::::: .:: :: ..: ::          ::..:: 
NP_112 VLEKKFHTVSGSKCEIKVAQPKEVYQQQQ-YGS-GGRGNRNRGNRGSGGGGGGGGQSQSW
              220       230        240        250       260        

        290        300                                             
pF1KB8 --GYGKVSRRG-GHQNSYKPY                                       
         :::.   .: :.:..: :                                        
NP_112 NQGYGNYWNQGYGYQQGYGPGYGGYDYSPYGYYGYGPGYDYSQGSTNYGKSQRRGGHQNN
      270       280       290       300       310       320        

>>NP_112740 (OMIM: 607137,609115) heterogeneous nuclear   (420 aa)
 initn: 1107 init1: 934 opt: 988  Z-score: 616.5  bits: 122.6 E(85289): 1.3e-27
Smith-Waterman score: 1007; 60.8% identity (80.4% similar) in 250 aa overlap (63-302:133-363)

             40        50        60        70        80        90  
pF1KB8 ATQGAAAAAGSGAGTGGGTASGGTEGGSAESEGAKIDASKNEEDEGHSNSSPRHSEAATA
                                     .::.::.::::..:.:              
NP_112 AATRTARQHPPADSSVTMEDMNEYSNIEEFAEGSKINASKNQQDDG--------------
            110       120       130       140                      

            100       110       120       130       140       150  
pF1KB8 QREEWKMFIGGLSWDTTKKDLKDYFSKFGEVVDCTLKLDPITGRSRGFGFVLFKESESVD
            :::::::::::.:::: .:.:.::::::::.: ::.:::::::::::::.. :::
NP_112 -----KMFIGGLSWDTSKKDLTEYLSRFGEVVDCTIKTDPVTGRSRGFGFVLFKDAASVD
           150       160       170       180       190       200   

            160       170       180       190       200       210  
pF1KB8 KVMDQKEHKLNGKVIDPKRAKAMKTKEPVKKIFVGGLSPDTPEEKIREYFGGFGEVESIE
       ::.. :::::.::.::::::::.: ::: ::.::::::::: ::.:.::::.:::.:.::
NP_112 KVLELKEHKLDGKLIDPKRAKALKGKEPPKKVFVGGLSPDTSEEQIKEYFGAFGEIENIE
           210       220       230       240       250       260   

            220       230       240       250       260            
pF1KB8 LPMDNKTNKRRGFCFITFKEEEPVKKIMEKKYHNVGLSKCEIKVAMSKEQYQQQQQW---
       ::::.:::.::::::::. .::::::..:..::..: .:::::::. :: :.::::    
NP_112 LPMDTKTNERRGFCFITYTDEEPVKKLLESRYHQIGSGKCEIKVAQPKEVYRQQQQQQKG
           270       280       290       300       310       320   

           270       280       290        300                      
pF1KB8 ------GSRGGFAGRARGRGGDQQSGYGKVSRRG-GHQNSYKPY                
             :.:::  ::.::.: . ..:...   .: :. ::                    
NP_112 GRGAAAGGRGGTRGRGRGQGQNWNQGFNNYYDQGYGNYNSAYGGDQNYSGYGGYDYTGYN
           330       340       350       360       370       380   

NP_112 YGNYGYGQGYADYSGQQSTYGKASRGGGNHQNNYQPY
           390       400       410       420

>>NP_001317180 (OMIM: 605372) heterogeneous nuclear ribo  (331 aa)
 initn: 675 init1: 333 opt: 606  Z-score: 388.9  bits: 80.2 E(85289): 6.4e-15
Smith-Waterman score: 606; 39.5% identity (70.8% similar) in 243 aa overlap (69-303:13-249)

       40        50        60        70        80        90        
pF1KB8 AAAGSGAGTGGGTASGGTEGGSAESEGAKIDASKNEEDEGHSNSSPRHSEAATAQREEWK
                                     :... .. .:. . .:.. :         :
NP_001                   MEVKPPPGRPQPDSGRRRRRRGEEGHDPKEPEQLR------K
                                 10        20        30            

      100       110       120       130       140       150        
pF1KB8 MFIGGLSWDTTKKDLKDYFSKFGEVVDCTLKLDPITGRSRGFGFVLFKESESVDKVMDQK
       .::::::..::  .:...: :.: ..::..  :: : :::::::: ..  : :: .:  .
NP_001 LFIGGLSFETTDDSLREHFEKWGTLTDCVVMRDPQTKRSRGFGFVTYSCVEEVDAAMCAR
         40        50        60        70        80        90      

      160       170        180            190       200       210  
pF1KB8 EHKLNGKVIDPKRAKAMKTK-EP-----VKKIFVGGLSPDTPEEKIREYFGGFGEVESIE
        ::..:.:..:::: . . . .:     ::::::::.. :: : ..:.::  .:..:.::
NP_001 PHKVDGRVVEPKRAVSREDSVKPGAHLTVKKIFVGGIKEDTEEYNLRDYFEKYGKIETIE
        100       110       120       130       140       150      

            220       230       240       250       260       270  
pF1KB8 LPMDNKTNKRRGFCFITFKEEEPVKKIMEKKYHNVGLSKCEIKVAMSKEQYQQQQQWGSR
       .  : ...:.::: :.:: ... : ::. .:::...  .::.: :.::...:.  .  .:
NP_001 VMEDRQSGKKRGFAFVTFDDHDTVDKIVVQKYHTINGHNCEVKKALSKQEMQSAGSQRGR
        160       170       180       190       200       210      

            280       290         300                              
pF1KB8 GGFAGRARGRGGDQQSGYGKVSRRG--GHQNSYKPY                        
       :: .:   ::::.  .: :. .: :  : ...:                           
NP_001 GGGSGNFMGRGGNFGGGGGNFGRGGNFGGRGGYGGGGGGSRGSYGGGDGGYNGFGGDGNY
        220       230       240       250       260       270      

NP_001 GGGGNYNDFGNYSGQQQSNYGPMKGGSFGGRSSGSPYGGGYGSGGGSGGYGSRRF
        280       290       300       310       320       330 

>>NP_001317179 (OMIM: 605372) heterogeneous nuclear ribo  (331 aa)
 initn: 675 init1: 333 opt: 606  Z-score: 388.9  bits: 80.2 E(85289): 6.4e-15
Smith-Waterman score: 606; 39.5% identity (70.8% similar) in 243 aa overlap (69-303:13-249)

       40        50        60        70        80        90        
pF1KB8 AAAGSGAGTGGGTASGGTEGGSAESEGAKIDASKNEEDEGHSNSSPRHSEAATAQREEWK
                                     :... .. .:. . .:.. :         :
NP_001                   MEVKPPPGRPQPDSGRRRRRRGEEGHDPKEPEQLR------K
                                 10        20        30            

      100       110       120       130       140       150        
pF1KB8 MFIGGLSWDTTKKDLKDYFSKFGEVVDCTLKLDPITGRSRGFGFVLFKESESVDKVMDQK
       .::::::..::  .:...: :.: ..::..  :: : :::::::: ..  : :: .:  .
NP_001 LFIGGLSFETTDDSLREHFEKWGTLTDCVVMRDPQTKRSRGFGFVTYSCVEEVDAAMCAR
         40        50        60        70        80        90      

      160       170        180            190       200       210  
pF1KB8 EHKLNGKVIDPKRAKAMKTK-EP-----VKKIFVGGLSPDTPEEKIREYFGGFGEVESIE
        ::..:.:..:::: . . . .:     ::::::::.. :: : ..:.::  .:..:.::
NP_001 PHKVDGRVVEPKRAVSREDSVKPGAHLTVKKIFVGGIKEDTEEYNLRDYFEKYGKIETIE
        100       110       120       130       140       150      

            220       230       240       250       260       270  
pF1KB8 LPMDNKTNKRRGFCFITFKEEEPVKKIMEKKYHNVGLSKCEIKVAMSKEQYQQQQQWGSR
       .  : ...:.::: :.:: ... : ::. .:::...  .::.: :.::...:.  .  .:
NP_001 VMEDRQSGKKRGFAFVTFDDHDTVDKIVVQKYHTINGHNCEVKKALSKQEMQSAGSQRGR
        160       170       180       190       200       210      

            280       290         300                              
pF1KB8 GGFAGRARGRGGDQQSGYGKVSRRG--GHQNSYKPY                        
       :: .:   ::::.  .: :. .: :  : ...:                           
NP_001 GGGSGNFMGRGGNFGGGGGNFGRGGNFGGRGGYGGGGGGSRGSYGGGDGGYNGFGGDGNY
        220       230       240       250       260       270      

NP_001 GGGGNYNDFGNYSGQQQSNYGPMKGGSFGGRSSGSPYGGGYGSGGGSGGYGSRRF
        280       290       300       310       320       330 




306 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Fri Nov  4 11:18:24 2016 done: Fri Nov  4 11:18:25 2016
 Total Scan time:  7.260 Total Display time:  0.010

Function used was FASTA [36.3.4 Apr, 2011]
Inquiries or Suggestions ?
Send a message to flexiclone AT kazusagt.com