FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB8275, 306 aa
1>>>pF1KB8275 306 - 306 aa - 306 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.6529+/-0.000443; mu= 13.6149+/- 0.028
mean_var=279.4367+/-62.180, 0's: 0 Z-trim(118.8): 164 B-trim: 1880 in 1/55
Lambda= 0.076724
statistics sampled from 31864 (32098) to 31864 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.72), E-opt: 0.2 (0.376), width: 16
Scan time: 7.260
The best scores are: opt bits E(85289)
NP_002129 (OMIM: 601324) heterogeneous nuclear rib ( 306) 2042 239.1 8.6e-63
NP_112738 (OMIM: 601324) heterogeneous nuclear rib ( 355) 1887 222.0 1.4e-57
NP_001003810 (OMIM: 601324) heterogeneous nuclear ( 287) 1487 177.6 2.6e-44
NP_112737 (OMIM: 601324) heterogeneous nuclear rib ( 336) 1332 160.5 4.1e-39
NP_001193929 (OMIM: 607137,609115) heterogeneous n ( 363) 1071 131.7 2.1e-30
NP_004490 (OMIM: 602688) heterogeneous nuclear rib ( 285) 1065 130.9 3e-30
NP_112556 (OMIM: 602688) heterogeneous nuclear rib ( 332) 988 122.5 1.2e-27
NP_112740 (OMIM: 607137,609115) heterogeneous nucl ( 420) 988 122.6 1.3e-27
NP_001317180 (OMIM: 605372) heterogeneous nuclear ( 331) 606 80.2 6.4e-15
NP_001317179 (OMIM: 605372) heterogeneous nuclear ( 331) 606 80.2 6.4e-15
NP_919223 (OMIM: 605372) heterogeneous nuclear rib ( 378) 606 80.3 6.8e-15
NP_001317178 (OMIM: 605372) heterogeneous nuclear ( 378) 606 80.3 6.8e-15
NP_001317177 (OMIM: 605372) heterogeneous nuclear ( 356) 600 79.6 1e-14
NP_001317176 (OMIM: 605372) heterogeneous nuclear ( 356) 600 79.6 1e-14
NP_002128 (OMIM: 600124,615422) heterogeneous nucl ( 341) 576 76.9 6.4e-14
XP_016867598 (OMIM: 600124,615422) PREDICTED: hete ( 341) 576 76.9 6.4e-14
XP_016867599 (OMIM: 600124,615422) PREDICTED: hete ( 341) 576 76.9 6.4e-14
NP_112533 (OMIM: 600124,615422) heterogeneous nucl ( 353) 576 76.9 6.6e-14
XP_005249786 (OMIM: 600124,615422) PREDICTED: hete ( 353) 576 76.9 6.6e-14
XP_016874740 (OMIM: 164017,615424,615426) PREDICTE ( 295) 557 74.7 2.6e-13
NP_002127 (OMIM: 164017,615424,615426) heterogeneo ( 320) 557 74.7 2.7e-13
XP_005268883 (OMIM: 164017,615424,615426) PREDICTE ( 372) 557 74.8 2.9e-13
NP_112420 (OMIM: 164017,615424,615426) heterogeneo ( 372) 557 74.8 2.9e-13
NP_001309180 (OMIM: 607897) RNA-binding protein Mu ( 255) 552 74.0 3.5e-13
XP_016879637 (OMIM: 607897) PREDICTED: RNA-binding ( 295) 552 74.1 3.8e-13
NP_620412 (OMIM: 607897) RNA-binding protein Musas ( 328) 552 74.2 4e-13
XP_005257072 (OMIM: 607897) PREDICTED: RNA-binding ( 346) 552 74.2 4.1e-13
XP_005257071 (OMIM: 607897) PREDICTED: RNA-binding ( 346) 552 74.2 4.1e-13
NP_733839 (OMIM: 607897) RNA-binding protein Musas ( 251) 542 72.9 7.5e-13
NP_001309179 (OMIM: 607897) RNA-binding protein Mu ( 324) 536 72.4 1.4e-12
XP_011536665 (OMIM: 603328) PREDICTED: RNA-binding ( 332) 523 71.0 3.7e-12
XP_011536664 (OMIM: 603328) PREDICTED: RNA-binding ( 343) 523 71.0 3.8e-12
XP_006719466 (OMIM: 603328) PREDICTED: RNA-binding ( 351) 523 71.0 3.8e-12
NP_002433 (OMIM: 603328) RNA-binding protein Musas ( 362) 523 71.0 3.9e-12
XP_011536663 (OMIM: 603328) PREDICTED: RNA-binding ( 362) 523 71.0 3.9e-12
NP_006796 (OMIM: 609409) heterogeneous nuclear rib ( 305) 471 65.2 1.9e-10
XP_016856353 (OMIM: 605078,612069) PREDICTED: TAR ( 414) 386 56.0 1.5e-07
XP_016856357 (OMIM: 605078,612069) PREDICTED: TAR ( 414) 386 56.0 1.5e-07
XP_016856354 (OMIM: 605078,612069) PREDICTED: TAR ( 414) 386 56.0 1.5e-07
XP_016856352 (OMIM: 605078,612069) PREDICTED: TAR ( 414) 386 56.0 1.5e-07
XP_016856356 (OMIM: 605078,612069) PREDICTED: TAR ( 414) 386 56.0 1.5e-07
NP_031401 (OMIM: 605078,612069) TAR DNA-binding pr ( 414) 386 56.0 1.5e-07
XP_016856355 (OMIM: 605078,612069) PREDICTED: TAR ( 414) 386 56.0 1.5e-07
XP_016879636 (OMIM: 607897) PREDICTED: RNA-binding ( 315) 334 50.0 7.2e-06
XP_016882071 (OMIM: 607430) PREDICTED: DAZ-associa ( 327) 290 45.2 0.00021
XP_011526209 (OMIM: 607430) PREDICTED: DAZ-associa ( 548) 293 45.9 0.00022
XP_011526208 (OMIM: 607430) PREDICTED: DAZ-associa ( 549) 293 45.9 0.00022
XP_005259588 (OMIM: 607430) PREDICTED: DAZ-associa ( 406) 290 45.3 0.00024
XP_011526210 (OMIM: 607430) PREDICTED: DAZ-associa ( 521) 290 45.5 0.00027
XP_011526211 (OMIM: 607430) PREDICTED: DAZ-associa ( 521) 290 45.5 0.00027
>>NP_002129 (OMIM: 601324) heterogeneous nuclear ribonuc (306 aa)
initn: 2042 init1: 2042 opt: 2042 Z-score: 1248.3 bits: 239.1 E(85289): 8.6e-63
Smith-Waterman score: 2042; 100.0% identity (100.0% similar) in 306 aa overlap (1-306:1-306)
10 20 30 40 50 60
pF1KB8 MSEEQFGGDGAAAAATAAVGGSAGEQEGAMVAATQGAAAAAGSGAGTGGGTASGGTEGGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 MSEEQFGGDGAAAAATAAVGGSAGEQEGAMVAATQGAAAAAGSGAGTGGGTASGGTEGGS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 AESEGAKIDASKNEEDEGHSNSSPRHSEAATAQREEWKMFIGGLSWDTTKKDLKDYFSKF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 AESEGAKIDASKNEEDEGHSNSSPRHSEAATAQREEWKMFIGGLSWDTTKKDLKDYFSKF
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 GEVVDCTLKLDPITGRSRGFGFVLFKESESVDKVMDQKEHKLNGKVIDPKRAKAMKTKEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 GEVVDCTLKLDPITGRSRGFGFVLFKESESVDKVMDQKEHKLNGKVIDPKRAKAMKTKEP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 VKKIFVGGLSPDTPEEKIREYFGGFGEVESIELPMDNKTNKRRGFCFITFKEEEPVKKIM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 VKKIFVGGLSPDTPEEKIREYFGGFGEVESIELPMDNKTNKRRGFCFITFKEEEPVKKIM
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 EKKYHNVGLSKCEIKVAMSKEQYQQQQQWGSRGGFAGRARGRGGDQQSGYGKVSRRGGHQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 EKKYHNVGLSKCEIKVAMSKEQYQQQQQWGSRGGFAGRARGRGGDQQSGYGKVSRRGGHQ
250 260 270 280 290 300
pF1KB8 NSYKPY
::::::
NP_002 NSYKPY
>>NP_112738 (OMIM: 601324) heterogeneous nuclear ribonuc (355 aa)
initn: 2309 init1: 1886 opt: 1887 Z-score: 1154.9 bits: 222.0 E(85289): 1.4e-57
Smith-Waterman score: 1887; 93.8% identity (96.4% similar) in 307 aa overlap (1-303:1-307)
10 20 30 40 50 60
pF1KB8 MSEEQFGGDGAAAAATAAVGGSAGEQEGAMVAATQGAAAAAGSGAGTGGGTASGGTEGGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_112 MSEEQFGGDGAAAAATAAVGGSAGEQEGAMVAATQGAAAAAGSGAGTGGGTASGGTEGGS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 AESEGAKIDASKNEEDEGHSNSSPRHSEAATAQREEWKMFIGGLSWDTTKKDLKDYFSKF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_112 AESEGAKIDASKNEEDEGHSNSSPRHSEAATAQREEWKMFIGGLSWDTTKKDLKDYFSKF
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 GEVVDCTLKLDPITGRSRGFGFVLFKESESVDKVMDQKEHKLNGKVIDPKRAKAMKTKEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_112 GEVVDCTLKLDPITGRSRGFGFVLFKESESVDKVMDQKEHKLNGKVIDPKRAKAMKTKEP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 VKKIFVGGLSPDTPEEKIREYFGGFGEVESIELPMDNKTNKRRGFCFITFKEEEPVKKIM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_112 VKKIFVGGLSPDTPEEKIREYFGGFGEVESIELPMDNKTNKRRGFCFITFKEEEPVKKIM
190 200 210 220 230 240
250 260 270 280 290
pF1KB8 EKKYHNVGLSKCEIKVAMSKEQYQQQQQWGSRGGFAGRARGRGG----DQQSGYGKVSRR
:::::::::::::::::::::::::::::::::::::::::::: . ..::.. .
NP_112 EKKYHNVGLSKCEIKVAMSKEQYQQQQQWGSRGGFAGRARGRGGGPSQNWNQGYSNYWNQ
250 260 270 280 290 300
300
pF1KB8 GGHQNSYKPY
: . .:
NP_112 GYGNYGYNSQGYGGYGGYDYTGYNNYYGYGDYSNQQSGYGKVSRRGGHQNSYKPY
310 320 330 340 350
>>NP_001003810 (OMIM: 601324) heterogeneous nuclear ribo (287 aa)
initn: 1438 init1: 1438 opt: 1487 Z-score: 916.5 bits: 177.6 E(85289): 2.6e-44
Smith-Waterman score: 1863; 93.8% identity (93.8% similar) in 306 aa overlap (1-306:1-287)
10 20 30 40 50 60
pF1KB8 MSEEQFGGDGAAAAATAAVGGSAGEQEGAMVAATQGAAAAAGSGAGTGGGTASGGTEGGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MSEEQFGGDGAAAAATAAVGGSAGEQEGAMVAATQGAAAAAGSGAGTGGGTASGGTEGGS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 AESEGAKIDASKNEEDEGHSNSSPRHSEAATAQREEWKMFIGGLSWDTTKKDLKDYFSKF
:::::::::::::::::: :::::::::::::::::::::::
NP_001 AESEGAKIDASKNEEDEG-------------------KMFIGGLSWDTTKKDLKDYFSKF
70 80 90 100
130 140 150 160 170 180
pF1KB8 GEVVDCTLKLDPITGRSRGFGFVLFKESESVDKVMDQKEHKLNGKVIDPKRAKAMKTKEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GEVVDCTLKLDPITGRSRGFGFVLFKESESVDKVMDQKEHKLNGKVIDPKRAKAMKTKEP
110 120 130 140 150 160
190 200 210 220 230 240
pF1KB8 VKKIFVGGLSPDTPEEKIREYFGGFGEVESIELPMDNKTNKRRGFCFITFKEEEPVKKIM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VKKIFVGGLSPDTPEEKIREYFGGFGEVESIELPMDNKTNKRRGFCFITFKEEEPVKKIM
170 180 190 200 210 220
250 260 270 280 290 300
pF1KB8 EKKYHNVGLSKCEIKVAMSKEQYQQQQQWGSRGGFAGRARGRGGDQQSGYGKVSRRGGHQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EKKYHNVGLSKCEIKVAMSKEQYQQQQQWGSRGGFAGRARGRGGDQQSGYGKVSRRGGHQ
230 240 250 260 270 280
pF1KB8 NSYKPY
::::::
NP_001 NSYKPY
>>NP_112737 (OMIM: 601324) heterogeneous nuclear ribonuc (336 aa)
initn: 2054 init1: 1269 opt: 1332 Z-score: 823.1 bits: 160.5 E(85289): 4.1e-39
Smith-Waterman score: 1708; 87.6% identity (90.2% similar) in 307 aa overlap (1-303:1-288)
10 20 30 40 50 60
pF1KB8 MSEEQFGGDGAAAAATAAVGGSAGEQEGAMVAATQGAAAAAGSGAGTGGGTASGGTEGGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_112 MSEEQFGGDGAAAAATAAVGGSAGEQEGAMVAATQGAAAAAGSGAGTGGGTASGGTEGGS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 AESEGAKIDASKNEEDEGHSNSSPRHSEAATAQREEWKMFIGGLSWDTTKKDLKDYFSKF
:::::::::::::::::: :::::::::::::::::::::::
NP_112 AESEGAKIDASKNEEDEG-------------------KMFIGGLSWDTTKKDLKDYFSKF
70 80 90 100
130 140 150 160 170 180
pF1KB8 GEVVDCTLKLDPITGRSRGFGFVLFKESESVDKVMDQKEHKLNGKVIDPKRAKAMKTKEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_112 GEVVDCTLKLDPITGRSRGFGFVLFKESESVDKVMDQKEHKLNGKVIDPKRAKAMKTKEP
110 120 130 140 150 160
190 200 210 220 230 240
pF1KB8 VKKIFVGGLSPDTPEEKIREYFGGFGEVESIELPMDNKTNKRRGFCFITFKEEEPVKKIM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_112 VKKIFVGGLSPDTPEEKIREYFGGFGEVESIELPMDNKTNKRRGFCFITFKEEEPVKKIM
170 180 190 200 210 220
250 260 270 280 290
pF1KB8 EKKYHNVGLSKCEIKVAMSKEQYQQQQQWGSRGGFAGRARGRGG----DQQSGYGKVSRR
:::::::::::::::::::::::::::::::::::::::::::: . ..::.. .
NP_112 EKKYHNVGLSKCEIKVAMSKEQYQQQQQWGSRGGFAGRARGRGGGPSQNWNQGYSNYWNQ
230 240 250 260 270 280
300
pF1KB8 GGHQNSYKPY
: . .:
NP_112 GYGNYGYNSQGYGGYGGYDYTGYNNYYGYGDYSNQQSGYGKVSRRGGHQNSYKPY
290 300 310 320 330
>>NP_001193929 (OMIM: 607137,609115) heterogeneous nucle (363 aa)
initn: 1145 init1: 934 opt: 1071 Z-score: 666.7 bits: 131.7 E(85289): 2.1e-30
Smith-Waterman score: 1081; 65.6% identity (82.8% similar) in 250 aa overlap (63-306:133-363)
40 50 60 70 80 90
pF1KB8 ATQGAAAAAGSGAGTGGGTASGGTEGGSAESEGAKIDASKNEEDEGHSNSSPRHSEAATA
.::.::.::::..:.:
NP_001 AATRTARQHPPADSSVTMEDMNEYSNIEEFAEGSKINASKNQQDDG--------------
110 120 130 140
100 110 120 130 140 150
pF1KB8 QREEWKMFIGGLSWDTTKKDLKDYFSKFGEVVDCTLKLDPITGRSRGFGFVLFKESESVD
:::::::::::.:::: .:.:.::::::::.: ::.:::::::::::::.. :::
NP_001 -----KMFIGGLSWDTSKKDLTEYLSRFGEVVDCTIKTDPVTGRSRGFGFVLFKDAASVD
150 160 170 180 190 200
160 170 180 190 200 210
pF1KB8 KVMDQKEHKLNGKVIDPKRAKAMKTKEPVKKIFVGGLSPDTPEEKIREYFGGFGEVESIE
::.. :::::.::.::::::::.: ::: ::.::::::::: ::.:.::::.:::.:.::
NP_001 KVLELKEHKLDGKLIDPKRAKALKGKEPPKKVFVGGLSPDTSEEQIKEYFGAFGEIENIE
210 220 230 240 250 260
220 230 240 250 260 270
pF1KB8 LPMDNKTNKRRGFCFITFKEEEPVKKIMEKKYHNVGLSKCEIKVAMSKEQY--QQQQQWG
::::.:::.::::::::. .::::::..:..::..: .:::::::. :: : ::::: :
NP_001 LPMDTKTNERRGFCFITYTDEEPVKKLLESRYHQIGSGKCEIKVAQPKEVYRQQQQQQKG
270 280 290 300 310 320
280 290 300
pF1KB8 SRGGFAGR---ARGRGGDQQSGYGKVSRRGG-HQNSYKPY
.::. :: .:::: ::: :::.:: :: :::.:.::
NP_001 GRGAAAGGRGGTRGRGRGQQSTYGKASRGGGNHQNNYQPY
330 340 350 360
>>NP_004490 (OMIM: 602688) heterogeneous nuclear ribonuc (285 aa)
initn: 1075 init1: 474 opt: 1065 Z-score: 664.1 bits: 130.9 E(85289): 3e-30
Smith-Waterman score: 1124; 60.5% identity (79.4% similar) in 296 aa overlap (22-306:12-285)
10 20 30 40 50
pF1KB8 MSEEQFGGDGAAAAATAAVGGSAGEQEGAMVAATQGAA-AAAGSGAGTGGGTASGGTEGG
..: :.. :. .: . :.::.::..:.: :... .:
NP_004 MSEAGEEQPMETTGATENGHEAVPEGESPAGAGTGAAAGAGGATAAPPSG
10 20 30 40 50
60 70 80 90 100 110
pF1KB8 SAE-SEGAKIDASKNEEDEGHSNSSPRHSEAATAQREEWKMFIGGLSWDTTKKDLKDYFS
. . .:: .:.::::::: : :::.:::::::.::::::::.
NP_004 NQNGAEGDQINASKNEEDAG-------------------KMFVGGLSWDTSKKDLKDYFT
60 70 80 90
120 130 140 150 160 170
pF1KB8 KFGEVVDCTLKLDPITGRSRGFGFVLFKESESVDKVMDQKEHKLNGKVIDPKRAKAMKTK
:::::::::.:.:: :::::::::.:::.. ::.::.:::::.:.:.:::::.: ::: :
NP_004 KFGEVVDCTIKMDPNTGRSRGFGFILFKDAASVEKVLDQKEHRLDGRVIDPKKAMAMK-K
100 110 120 130 140 150
180 190 200 210 220 230
pF1KB8 EPVKKIFVGGLSPDTPEEKIREYFGGFGEVESIELPMDNKTNKRRGFCFITFKEEEPVKK
.::::::::::.:.. ::::::::: :::.:.:::::: : :::::: ::::::::::::
NP_004 DPVKKIFVGGLNPEATEEKIREYFGEFGEIEAIELPMDPKLNKRRGFVFITFKEEEPVKK
160 170 180 190 200 210
240 250 260 270 280
pF1KB8 IMEKKYHNVGLSKCEIKVAMSKEQYQQQQQWGSRGGFAGRARGR---------GGDQQSG
..:::.:.:. ::::::::. :: ::::: .:: :: ..: :: ::. ...
NP_004 VLEKKFHTVSGSKCEIKVAQPKEVYQQQQ-YGS-GGRGNRNRGNRGSGGGGGGGGQGSTN
220 230 240 250 260
290 300
pF1KB8 YGKVSRRGGHQNSYKPY
::: .:::::::.::::
NP_004 YGKSQRRGGHQNNYKPY
270 280
>>NP_112556 (OMIM: 602688) heterogeneous nuclear ribonuc (332 aa)
initn: 1105 init1: 474 opt: 988 Z-score: 617.4 bits: 122.5 E(85289): 1.2e-27
Smith-Waterman score: 1061; 58.5% identity (77.6% similar) in 299 aa overlap (22-305:12-288)
10 20 30 40 50
pF1KB8 MSEEQFGGDGAAAAATAAVGGSAGEQEGAMVAATQGAA-AAAGSGAGTGGGTASGGTEGG
..: :.. :. .: . :.::.::..:.: :... .:
NP_112 MSEAGEEQPMETTGATENGHEAVPEGESPAGAGTGAAAGAGGATAAPPSG
10 20 30 40 50
60 70 80 90 100 110
pF1KB8 SAE-SEGAKIDASKNEEDEGHSNSSPRHSEAATAQREEWKMFIGGLSWDTTKKDLKDYFS
. . .:: .:.::::::: : :::.:::::::.::::::::.
NP_112 NQNGAEGDQINASKNEEDAG-------------------KMFVGGLSWDTSKKDLKDYFT
60 70 80 90
120 130 140 150 160 170
pF1KB8 KFGEVVDCTLKLDPITGRSRGFGFVLFKESESVDKVMDQKEHKLNGKVIDPKRAKAMKTK
:::::::::.:.:: :::::::::.:::.. ::.::.:::::.:.:.:::::.: ::: :
NP_112 KFGEVVDCTIKMDPNTGRSRGFGFILFKDAASVEKVLDQKEHRLDGRVIDPKKAMAMK-K
100 110 120 130 140 150
180 190 200 210 220 230
pF1KB8 EPVKKIFVGGLSPDTPEEKIREYFGGFGEVESIELPMDNKTNKRRGFCFITFKEEEPVKK
.::::::::::.:.. ::::::::: :::.:.:::::: : :::::: ::::::::::::
NP_112 DPVKKIFVGGLNPEATEEKIREYFGEFGEIEAIELPMDPKLNKRRGFVFITFKEEEPVKK
160 170 180 190 200 210
240 250 260 270 280
pF1KB8 IMEKKYHNVGLSKCEIKVAMSKEQYQQQQQWGSRGGFAGRARGR---------GGDQQS-
..:::.:.:. ::::::::. :: ::::: .:: :: ..: :: ::..::
NP_112 VLEKKFHTVSGSKCEIKVAQPKEVYQQQQ-YGS-GGRGNRNRGNRGSGGGGGGGGQSQSW
220 230 240 250 260
290 300
pF1KB8 --GYGKVSRRG-GHQNSYKPY
:::. .: :.:..: :
NP_112 NQGYGNYWNQGYGYQQGYGPGYGGYDYSPYGYYGYGPGYDYSQGSTNYGKSQRRGGHQNN
270 280 290 300 310 320
>>NP_112740 (OMIM: 607137,609115) heterogeneous nuclear (420 aa)
initn: 1107 init1: 934 opt: 988 Z-score: 616.5 bits: 122.6 E(85289): 1.3e-27
Smith-Waterman score: 1007; 60.8% identity (80.4% similar) in 250 aa overlap (63-302:133-363)
40 50 60 70 80 90
pF1KB8 ATQGAAAAAGSGAGTGGGTASGGTEGGSAESEGAKIDASKNEEDEGHSNSSPRHSEAATA
.::.::.::::..:.:
NP_112 AATRTARQHPPADSSVTMEDMNEYSNIEEFAEGSKINASKNQQDDG--------------
110 120 130 140
100 110 120 130 140 150
pF1KB8 QREEWKMFIGGLSWDTTKKDLKDYFSKFGEVVDCTLKLDPITGRSRGFGFVLFKESESVD
:::::::::::.:::: .:.:.::::::::.: ::.:::::::::::::.. :::
NP_112 -----KMFIGGLSWDTSKKDLTEYLSRFGEVVDCTIKTDPVTGRSRGFGFVLFKDAASVD
150 160 170 180 190 200
160 170 180 190 200 210
pF1KB8 KVMDQKEHKLNGKVIDPKRAKAMKTKEPVKKIFVGGLSPDTPEEKIREYFGGFGEVESIE
::.. :::::.::.::::::::.: ::: ::.::::::::: ::.:.::::.:::.:.::
NP_112 KVLELKEHKLDGKLIDPKRAKALKGKEPPKKVFVGGLSPDTSEEQIKEYFGAFGEIENIE
210 220 230 240 250 260
220 230 240 250 260
pF1KB8 LPMDNKTNKRRGFCFITFKEEEPVKKIMEKKYHNVGLSKCEIKVAMSKEQYQQQQQW---
::::.:::.::::::::. .::::::..:..::..: .:::::::. :: :.::::
NP_112 LPMDTKTNERRGFCFITYTDEEPVKKLLESRYHQIGSGKCEIKVAQPKEVYRQQQQQQKG
270 280 290 300 310 320
270 280 290 300
pF1KB8 ------GSRGGFAGRARGRGGDQQSGYGKVSRRG-GHQNSYKPY
:.::: ::.::.: . ..:... .: :. ::
NP_112 GRGAAAGGRGGTRGRGRGQGQNWNQGFNNYYDQGYGNYNSAYGGDQNYSGYGGYDYTGYN
330 340 350 360 370 380
NP_112 YGNYGYGQGYADYSGQQSTYGKASRGGGNHQNNYQPY
390 400 410 420
>>NP_001317180 (OMIM: 605372) heterogeneous nuclear ribo (331 aa)
initn: 675 init1: 333 opt: 606 Z-score: 388.9 bits: 80.2 E(85289): 6.4e-15
Smith-Waterman score: 606; 39.5% identity (70.8% similar) in 243 aa overlap (69-303:13-249)
40 50 60 70 80 90
pF1KB8 AAAGSGAGTGGGTASGGTEGGSAESEGAKIDASKNEEDEGHSNSSPRHSEAATAQREEWK
:... .. .:. . .:.. : :
NP_001 MEVKPPPGRPQPDSGRRRRRRGEEGHDPKEPEQLR------K
10 20 30
100 110 120 130 140 150
pF1KB8 MFIGGLSWDTTKKDLKDYFSKFGEVVDCTLKLDPITGRSRGFGFVLFKESESVDKVMDQK
.::::::..:: .:...: :.: ..::.. :: : :::::::: .. : :: .: .
NP_001 LFIGGLSFETTDDSLREHFEKWGTLTDCVVMRDPQTKRSRGFGFVTYSCVEEVDAAMCAR
40 50 60 70 80 90
160 170 180 190 200 210
pF1KB8 EHKLNGKVIDPKRAKAMKTK-EP-----VKKIFVGGLSPDTPEEKIREYFGGFGEVESIE
::..:.:..:::: . . . .: ::::::::.. :: : ..:.:: .:..:.::
NP_001 PHKVDGRVVEPKRAVSREDSVKPGAHLTVKKIFVGGIKEDTEEYNLRDYFEKYGKIETIE
100 110 120 130 140 150
220 230 240 250 260 270
pF1KB8 LPMDNKTNKRRGFCFITFKEEEPVKKIMEKKYHNVGLSKCEIKVAMSKEQYQQQQQWGSR
. : ...:.::: :.:: ... : ::. .:::... .::.: :.::...:. . .:
NP_001 VMEDRQSGKKRGFAFVTFDDHDTVDKIVVQKYHTINGHNCEVKKALSKQEMQSAGSQRGR
160 170 180 190 200 210
280 290 300
pF1KB8 GGFAGRARGRGGDQQSGYGKVSRRG--GHQNSYKPY
:: .: ::::. .: :. .: : : ...:
NP_001 GGGSGNFMGRGGNFGGGGGNFGRGGNFGGRGGYGGGGGGSRGSYGGGDGGYNGFGGDGNY
220 230 240 250 260 270
NP_001 GGGGNYNDFGNYSGQQQSNYGPMKGGSFGGRSSGSPYGGGYGSGGGSGGYGSRRF
280 290 300 310 320 330
>>NP_001317179 (OMIM: 605372) heterogeneous nuclear ribo (331 aa)
initn: 675 init1: 333 opt: 606 Z-score: 388.9 bits: 80.2 E(85289): 6.4e-15
Smith-Waterman score: 606; 39.5% identity (70.8% similar) in 243 aa overlap (69-303:13-249)
40 50 60 70 80 90
pF1KB8 AAAGSGAGTGGGTASGGTEGGSAESEGAKIDASKNEEDEGHSNSSPRHSEAATAQREEWK
:... .. .:. . .:.. : :
NP_001 MEVKPPPGRPQPDSGRRRRRRGEEGHDPKEPEQLR------K
10 20 30
100 110 120 130 140 150
pF1KB8 MFIGGLSWDTTKKDLKDYFSKFGEVVDCTLKLDPITGRSRGFGFVLFKESESVDKVMDQK
.::::::..:: .:...: :.: ..::.. :: : :::::::: .. : :: .: .
NP_001 LFIGGLSFETTDDSLREHFEKWGTLTDCVVMRDPQTKRSRGFGFVTYSCVEEVDAAMCAR
40 50 60 70 80 90
160 170 180 190 200 210
pF1KB8 EHKLNGKVIDPKRAKAMKTK-EP-----VKKIFVGGLSPDTPEEKIREYFGGFGEVESIE
::..:.:..:::: . . . .: ::::::::.. :: : ..:.:: .:..:.::
NP_001 PHKVDGRVVEPKRAVSREDSVKPGAHLTVKKIFVGGIKEDTEEYNLRDYFEKYGKIETIE
100 110 120 130 140 150
220 230 240 250 260 270
pF1KB8 LPMDNKTNKRRGFCFITFKEEEPVKKIMEKKYHNVGLSKCEIKVAMSKEQYQQQQQWGSR
. : ...:.::: :.:: ... : ::. .:::... .::.: :.::...:. . .:
NP_001 VMEDRQSGKKRGFAFVTFDDHDTVDKIVVQKYHTINGHNCEVKKALSKQEMQSAGSQRGR
160 170 180 190 200 210
280 290 300
pF1KB8 GGFAGRARGRGGDQQSGYGKVSRRG--GHQNSYKPY
:: .: ::::. .: :. .: : : ...:
NP_001 GGGSGNFMGRGGNFGGGGGNFGRGGNFGGRGGYGGGGGGSRGSYGGGDGGYNGFGGDGNY
220 230 240 250 260 270
NP_001 GGGGNYNDFGNYSGQQQSNYGPMKGGSFGGRSSGSPYGGGYGSGGGSGGYGSRRF
280 290 300 310 320 330
306 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 11:18:24 2016 done: Fri Nov 4 11:18:25 2016
Total Scan time: 7.260 Total Display time: 0.010
Function used was FASTA [36.3.4 Apr, 2011]