FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB8276, 139 aa 1>>>pF1KB8276 139 - 139 aa - 139 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.6832+/-0.000293; mu= 11.4847+/- 0.018 mean_var=121.6015+/-25.004, 0's: 0 Z-trim(120.6): 19 B-trim: 1900 in 1/55 Lambda= 0.116307 statistics sampled from 35944 (35965) to 35944 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.779), E-opt: 0.2 (0.422), width: 16 Scan time: 4.550 The best scores are: opt bits E(85289) NP_036453 (OMIM: 607284) U6 snRNA-associated Sm-li ( 139) 973 172.9 1.4e-43 NP_001239058 (OMIM: 607284) U6 snRNA-associated Sm ( 125) 881 157.5 5.9e-39 NP_004166 (OMIM: 601062) small nuclear ribonucleop ( 126) 216 45.9 2.3e-05 NP_001265585 (OMIM: 601062) small nuclear ribonucl ( 126) 216 45.9 2.3e-05 >>NP_036453 (OMIM: 607284) U6 snRNA-associated Sm-like p (139 aa) initn: 973 init1: 973 opt: 973 Z-score: 903.2 bits: 172.9 E(85289): 1.4e-43 Smith-Waterman score: 973; 100.0% identity (100.0% similar) in 139 aa overlap (1-139:1-139) 10 20 30 40 50 60 pF1KB8 MLPLSLLKTAQNHPMLVELKNGETYNGHLVSCDNWMNINLREVICTSRDGDKFWRMPECY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 MLPLSLLKTAQNHPMLVELKNGETYNGHLVSCDNWMNINLREVICTSRDGDKFWRMPECY 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 IRGSTIKYLRIPDEIIDMVKEEVVAKGRGRGGLQQQKQQKGRGMGGAGRGVFGGRGRGGI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 IRGSTIKYLRIPDEIIDMVKEEVVAKGRGRGGLQQQKQQKGRGMGGAGRGVFGGRGRGGI 70 80 90 100 110 120 130 pF1KB8 PGTGRGQPEKKPGRQAGKQ ::::::::::::::::::: NP_036 PGTGRGQPEKKPGRQAGKQ 130 >>NP_001239058 (OMIM: 607284) U6 snRNA-associated Sm-lik (125 aa) initn: 881 init1: 881 opt: 881 Z-score: 820.4 bits: 157.5 E(85289): 5.9e-39 Smith-Waterman score: 881; 100.0% identity (100.0% similar) in 125 aa overlap (15-139:1-125) 10 20 30 40 50 60 pF1KB8 MLPLSLLKTAQNHPMLVELKNGETYNGHLVSCDNWMNINLREVICTSRDGDKFWRMPECY :::::::::::::::::::::::::::::::::::::::::::::: NP_001 MLVELKNGETYNGHLVSCDNWMNINLREVICTSRDGDKFWRMPECY 10 20 30 40 70 80 90 100 110 120 pF1KB8 IRGSTIKYLRIPDEIIDMVKEEVVAKGRGRGGLQQQKQQKGRGMGGAGRGVFGGRGRGGI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IRGSTIKYLRIPDEIIDMVKEEVVAKGRGRGGLQQQKQQKGRGMGGAGRGVFGGRGRGGI 50 60 70 80 90 100 130 pF1KB8 PGTGRGQPEKKPGRQAGKQ ::::::::::::::::::: NP_001 PGTGRGQPEKKPGRQAGKQ 110 120 >>NP_004166 (OMIM: 601062) small nuclear ribonucleoprote (126 aa) initn: 241 init1: 114 opt: 216 Z-score: 217.3 bits: 45.9 E(85289): 2.3e-05 Smith-Waterman score: 216; 33.3% identity (62.6% similar) in 123 aa overlap (2-115:5-125) 10 20 30 40 50 pF1KB8 MLPLSLLKTAQNHPMLVELKNGETYNGHLVSCDNWMNINLREVICTSRDGDKFWRMP .:...:. :..: . : ..::.: :.:. .. :: .. .. : ::: . .. NP_004 MSIGVPIKVLHEAEGHIVTCETNTGEVYRGKLIEAEDNMNCQMSNITVTYRDG-RVAQLE 10 20 30 40 50 60 70 80 90 100 pF1KB8 ECYIRGSTIKYLRIPD-----EIIDMVKEEVVAKGRGRGG---LQQQKQQKGRGMGGAGR . ::::: :..: .:: .. .:.. ..: ::: :. : .::: : :: NP_004 QVYIRGSKIRFLILPDMLKNAPMLKSMKNKNQGSGAGRGKAAILKAQVAARGRGRG-MGR 60 70 80 90 100 110 110 120 130 pF1KB8 G-VFGGRGRGGIPGTGRGQPEKKPGRQAGKQ : .: : NP_004 GNIFQKRR 120 >>NP_001265585 (OMIM: 601062) small nuclear ribonucleopr (126 aa) initn: 241 init1: 114 opt: 216 Z-score: 217.3 bits: 45.9 E(85289): 2.3e-05 Smith-Waterman score: 216; 33.3% identity (62.6% similar) in 123 aa overlap (2-115:5-125) 10 20 30 40 50 pF1KB8 MLPLSLLKTAQNHPMLVELKNGETYNGHLVSCDNWMNINLREVICTSRDGDKFWRMP .:...:. :..: . : ..::.: :.:. .. :: .. .. : ::: . .. NP_001 MSIGVPIKVLHEAEGHIVTCETNTGEVYRGKLIEAEDNMNCQMSNITVTYRDG-RVAQLE 10 20 30 40 50 60 70 80 90 100 pF1KB8 ECYIRGSTIKYLRIPD-----EIIDMVKEEVVAKGRGRGG---LQQQKQQKGRGMGGAGR . ::::: :..: .:: .. .:.. ..: ::: :. : .::: : :: NP_001 QVYIRGSKIRFLILPDMLKNAPMLKSMKNKNQGSGAGRGKAAILKAQVAARGRGRG-MGR 60 70 80 90 100 110 110 120 130 pF1KB8 G-VFGGRGRGGIPGTGRGQPEKKPGRQAGKQ : .: : NP_001 GNIFQKRR 120 139 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 11:18:52 2016 done: Fri Nov 4 11:18:53 2016 Total Scan time: 4.550 Total Display time: -0.040 Function used was FASTA [36.3.4 Apr, 2011]