FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB8280, 190 aa 1>>>pF1KB8280 190 - 190 aa - 190 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.5746+/-0.000373; mu= 13.9005+/- 0.023 mean_var=158.7425+/-33.328, 0's: 0 Z-trim(117.9): 99 B-trim: 1548 in 1/53 Lambda= 0.101795 statistics sampled from 30127 (30241) to 30127 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.718), E-opt: 0.2 (0.355), width: 16 Scan time: 4.400 The best scores are: opt bits E(85289) NP_001171938 (OMIM: 602850) E3 ubiquitin-protein l ( 190) 1281 199.3 3.2e-51 NP_002929 (OMIM: 602850) E3 ubiquitin-protein liga ( 190) 1281 199.3 3.2e-51 NP_001171939 (OMIM: 602850) E3 ubiquitin-protein l ( 113) 440 75.4 3.6e-14 >>NP_001171938 (OMIM: 602850) E3 ubiquitin-protein ligas (190 aa) initn: 1281 init1: 1281 opt: 1281 Z-score: 1040.6 bits: 199.3 E(85289): 3.2e-51 Smith-Waterman score: 1281; 100.0% identity (100.0% similar) in 190 aa overlap (1-190:1-190) 10 20 30 40 50 60 pF1KB8 MSTRKRRGGAINSRQAQKRTREATSTPEISLEAEPIELVETAGDEIVDLTCESLEPVVVD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MSTRKRRGGAINSRQAQKRTREATSTPEISLEAEPIELVETAGDEIVDLTCESLEPVVVD 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 LTHNDSVVIVDERRRPRRNARRLPQDHADSCVVSSDDEELSRDRDVYVTTHTPRNARDEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LTHNDSVVIVDERRRPRRNARRLPQDHADSCVVSSDDEELSRDRDVYVTTHTPRNARDEG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 ATGLRPSGTVSCPICMDGYSEIVQNGRLIVSTECGHVFCSQCLRDSLKNANTCPTCRKKI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ATGLRPSGTVSCPICMDGYSEIVQNGRLIVSTECGHVFCSQCLRDSLKNANTCPTCRKKI 130 140 150 160 170 180 190 pF1KB8 NHKRYHPIYI :::::::::: NP_001 NHKRYHPIYI 190 >>NP_002929 (OMIM: 602850) E3 ubiquitin-protein ligase R (190 aa) initn: 1281 init1: 1281 opt: 1281 Z-score: 1040.6 bits: 199.3 E(85289): 3.2e-51 Smith-Waterman score: 1281; 100.0% identity (100.0% similar) in 190 aa overlap (1-190:1-190) 10 20 30 40 50 60 pF1KB8 MSTRKRRGGAINSRQAQKRTREATSTPEISLEAEPIELVETAGDEIVDLTCESLEPVVVD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 MSTRKRRGGAINSRQAQKRTREATSTPEISLEAEPIELVETAGDEIVDLTCESLEPVVVD 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 LTHNDSVVIVDERRRPRRNARRLPQDHADSCVVSSDDEELSRDRDVYVTTHTPRNARDEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 LTHNDSVVIVDERRRPRRNARRLPQDHADSCVVSSDDEELSRDRDVYVTTHTPRNARDEG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 ATGLRPSGTVSCPICMDGYSEIVQNGRLIVSTECGHVFCSQCLRDSLKNANTCPTCRKKI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 ATGLRPSGTVSCPICMDGYSEIVQNGRLIVSTECGHVFCSQCLRDSLKNANTCPTCRKKI 130 140 150 160 170 180 190 pF1KB8 NHKRYHPIYI :::::::::: NP_002 NHKRYHPIYI 190 >>NP_001171939 (OMIM: 602850) E3 ubiquitin-protein ligas (113 aa) initn: 440 init1: 440 opt: 440 Z-score: 375.4 bits: 75.4 E(85289): 3.6e-14 Smith-Waterman score: 443; 72.5% identity (78.9% similar) in 109 aa overlap (1-95:1-109) 10 20 30 40 50 60 pF1KB8 MSTRKRRGGAINSRQAQKRTREATSTPEISLEAEPIELVETAGDEIVDLTCESLEPVVVD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MSTRKRRGGAINSRQAQKRTREATSTPEISLEAEPIELVETAGDEIVDLTCESLEPVVVD 10 20 30 40 50 60 70 80 90 100 pF1KB8 LTHNDSVVIVD--------------ERRRPRRNARRLPQDHADSCVVSSDDEELSRDRDV ::::::::::: .: : .. .::. : : :.:. NP_001 LTHNDSVVIVDGPQVLSVVPSAWTDTQRSCRMDVSSFPQNAAMSSVASASVIP 70 80 90 100 110 110 120 130 140 150 160 pF1KB8 YVTTHTPRNARDEGATGLRPSGTVSCPICMDGYSEIVQNGRLIVSTECGHVFCSQCLRDS 190 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 11:20:07 2016 done: Fri Nov 4 11:20:07 2016 Total Scan time: 4.400 Total Display time: -0.030 Function used was FASTA [36.3.4 Apr, 2011]