FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB8284, 412 aa
  1>>>pF1KB8284 412 - 412 aa - 412 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 6.4771+/-0.000301; mu= 14.2164+/- 0.019
 mean_var=134.3362+/-27.511, 0's: 0 Z-trim(121.9): 72  B-trim: 1319 in 1/54
 Lambda= 0.110657
 statistics sampled from 38993 (39074) to 38993 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.786), E-opt: 0.2 (0.458), width:  16
 Scan time:  9.200

The best scores are:                                      opt bits E(85289)
NP_003661 (OMIM: 604256) class E basic helix-loop- ( 412) 2800 457.8 2.2e-128
NP_110389 (OMIM: 606200,612975) class E basic heli ( 482)  764 132.9 1.7e-30


>>NP_003661 (OMIM: 604256) class E basic helix-loop-heli  (412 aa)
 initn: 2800 init1: 2800 opt: 2800  Z-score: 2426.0  bits: 457.8 E(85289): 2.2e-128
Smith-Waterman score: 2800; 100.0% identity (100.0% similar) in 412 aa overlap (1-412:1-412)

               10        20        30        40        50        60
pF1KB8 MERIPSAQPPPACLPKAPGLEHGDLPGMYPAHMYQVYKSRRGIKRSEDSKETYKLPHRLI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 MERIPSAQPPPACLPKAPGLEHGDLPGMYPAHMYQVYKSRRGIKRSEDSKETYKLPHRLI
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB8 EKKRRDRINECIAQLKDLLPEHLKLTTLGHLEKAVVLELTLKHVKALTNLIDQQQQKIIA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 EKKRRDRINECIAQLKDLLPEHLKLTTLGHLEKAVVLELTLKHVKALTNLIDQQQQKIIA
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB8 LQSGLQAGELSGRNVETGQEMFCSGFQTCAREVLQYLAKHENTRDLKSSQLVTHLHRVVS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 LQSGLQAGELSGRNVETGQEMFCSGFQTCAREVLQYLAKHENTRDLKSSQLVTHLHRVVS
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB8 ELLQGGTSRKPSDPAPKVMDFKEKPSSPAKGSEGPGKNCVPVIQRTFAHSSGEQSGSDTD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 ELLQGGTSRKPSDPAPKVMDFKEKPSSPAKGSEGPGKNCVPVIQRTFAHSSGEQSGSDTD
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB8 TDSGYGGESEKGDLRSEQPCFKSDHGRRFTMGERIGAIKQESEEPPTKKNRMQLSDDEGH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 TDSGYGGESEKGDLRSEQPCFKSDHGRRFTMGERIGAIKQESEEPPTKKNRMQLSDDEGH
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB8 FTSSDLISSPFLGPHPHQPPFCLPFYLIPPSATAYLPMLEKCWYPTSVPVLYPGLNASAA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 FTSSDLISSPFLGPHPHQPPFCLPFYLIPPSATAYLPMLEKCWYPTSVPVLYPGLNASAA
              310       320       330       340       350       360

              370       380       390       400       410  
pF1KB8 ALSSFMNPDKISAPLLMPQRLPSPLPAHPSVDSSVLLQALKPIPPLNLETKD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 ALSSFMNPDKISAPLLMPQRLPSPLPAHPSVDSSVLLQALKPIPPLNLETKD
              370       380       390       400       410  

>>NP_110389 (OMIM: 606200,612975) class E basic helix-lo  (482 aa)
 initn: 823 init1: 447 opt: 764  Z-score: 668.5  bits: 132.9 E(85289): 1.7e-30
Smith-Waterman score: 838; 42.6% identity (61.4% similar) in 430 aa overlap (20-397:14-434)

               10        20        30        40        50        60
pF1KB8 MERIPSAQPPPACLPKAPGLEHGDLPGMYPAHMYQVYKSRRGIKRSEDSKETYKLPHRLI
                          ::: :. :.  . .:.  : .:..:: .:.:.:::::::::
NP_110       MDEGIPHLQERQLLEHRDFIGLDYSSLYMC-KPKRSMKR-DDTKDTYKLPHRLI
                     10        20        30          40        50  

               70        80        90       100       110       120
pF1KB8 EKKRRDRINECIAQLKDLLPEHLKLTTLGHLEKAVVLELTLKHVKALTNLIDQQQQKIIA
       :::::::::::::::::::::::::::::::::::::::::::.:::: : .::.:::::
NP_110 EKKRRDRINECIAQLKDLLPEHLKLTTLGHLEKAVVLELTLKHLKALTALTEQQHQKIIA
             60        70        80        90       100       110  

              130        140       150       160         170       
pF1KB8 LQSGLQAGELSGRN-VETGQEMFCSGFQTCAREVLQYLAKHEN--TRDLKSSQLVTHLHR
       ::.:    : : .. ...  . : :::::::.::::::.. :.   :. .  ::..::: 
NP_110 LQNG----ERSLKSPIQSDLDAFHSGFQTCAKEVLQYLSRFESWTPREPRCVQLINHLHA
                120       130       140       150       160        

       180          190          200       210        220       230
pF1KB8 VVSELL---QGGTSRKP---SDPAPKVMDFKEKPSSPAKGSE-GPGKNCVPVIQRTFAHS
       :....:   :  :.. :   .  ::..      :     :..  :   ::::::::  . 
NP_110 VATQFLPTPQLLTQQVPLSKGTGAPSAAGSAAAPCLERAGQKLEPLAYCVPVIQRT--QP
      170       180       190       200       210       220        

               240       250                     260       270     
pF1KB8 SGEQSG-SDTDTDSGYGGESE------KGD--------LRSEQPCFKSDHGRRFTMGERI
       :.: .. .:::::::::::.:      ::         ...: :   :   .:. .  : 
NP_110 SAELAAENDTDTDSGYGGEAEARPDREKGKGAGASRVTIKQEPPGEDSPAPKRMKLDSRG
        230       240       250       260       270       280      

                   280       290       300             310         
pF1KB8 G----------AIKQESEEPPTKKNRMQLSDDEGHFTSSDLIS------SPFLGPHPHQP
       :          :    .   :       :   .. . :: :..      .::  :     
NP_110 GGSGGGPGGGAAAAAAALLGPDPAAAAALLRPDAALLSS-LVAFGGGGGAPFPQPAAAAA
        290       300       310       320        330       340     

     320        330             340           350       360        
pF1KB8 PFCLPF-YLIPPSATAYL-PML-----EKCWYPTSV----PVLYPGLNASAAALSSFMNP
       :::::: .: : .:.::. :.:     ::  ::...    :.::::. : ::: ..    
NP_110 PFCLPFCFLSPSAAAAYVQPFLDKSGLEKYLYPAAAAAPFPLLYPGIPAPAAAAAAAAAA
         350       360       370       380       390       400     

      370       380       390       400       410                  
pF1KB8 DKISAPLLMPQRLPSPLPAHPSVDSSVLLQALKPIPPLNLETKD                
          .: .   . . :: : . .. ...::                               
NP_110 AAAAAAFPCLSSVLSPPPEKAGAAAATLLPHEVAPLGAPHPQHPHGRTHLPFAGPREPGN
         410       420       430       440       450       460     




412 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Fri Nov  4 11:23:06 2016 done: Fri Nov  4 11:23:08 2016
 Total Scan time:  9.200 Total Display time:  0.000

Function used was FASTA [36.3.4 Apr, 2011]