FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB8289, 302 aa 1>>>pF1KB8289 302 - 302 aa - 302 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 8.2671+/-0.0011; mu= 1.2375+/- 0.064 mean_var=270.7623+/-63.763, 0's: 0 Z-trim(111.5): 725 B-trim: 494 in 1/51 Lambda= 0.077944 statistics sampled from 11550 (12449) to 11550 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.75), E-opt: 0.2 (0.382), width: 16 Scan time: 2.820 The best scores are: opt bits E(32554) CCDS2373.1 KLF7 gene_id:8609|Hs108|chr2 ( 302) 2026 241.1 8e-64 CCDS59438.1 KLF7 gene_id:8609|Hs108|chr2 ( 274) 1806 216.3 2.1e-56 CCDS59440.1 KLF7 gene_id:8609|Hs108|chr2 ( 269) 1802 215.8 2.8e-56 CCDS59439.1 KLF7 gene_id:8609|Hs108|chr2 ( 230) 1140 141.3 6.6e-34 CCDS7060.1 KLF6 gene_id:1316|Hs108|chr10 ( 283) 703 92.3 4.7e-19 CCDS9449.1 KLF12 gene_id:11278|Hs108|chr13 ( 402) 567 77.2 2.4e-14 CCDS66562.1 KLF5 gene_id:688|Hs108|chr13 ( 366) 559 76.2 4.1e-14 CCDS3444.1 KLF3 gene_id:51274|Hs108|chr4 ( 345) 558 76.1 4.3e-14 CCDS9448.1 KLF5 gene_id:688|Hs108|chr13 ( 457) 559 76.3 4.8e-14 CCDS14373.1 KLF8 gene_id:11279|Hs108|chrX ( 359) 537 73.7 2.3e-13 CCDS12343.1 KLF2 gene_id:10365|Hs108|chr19 ( 355) 525 72.4 5.7e-13 CCDS6770.2 KLF4 gene_id:9314|Hs108|chr9 ( 479) 524 72.4 7.5e-13 CCDS12285.1 KLF1 gene_id:10661|Hs108|chr19 ( 362) 510 70.7 1.9e-12 CCDS3036.1 KLF15 gene_id:28999|Hs108|chr3 ( 416) 494 69.0 7.1e-12 >>CCDS2373.1 KLF7 gene_id:8609|Hs108|chr2 (302 aa) initn: 2026 init1: 2026 opt: 2026 Z-score: 1259.3 bits: 241.1 E(32554): 8e-64 Smith-Waterman score: 2026; 100.0% identity (100.0% similar) in 302 aa overlap (1-302:1-302) 10 20 30 40 50 60 pF1KB8 MDVLASYSIFQELQLVHDTGYFSALPSLEETWQQTCLELERYLQTEPRRISETFGEDLDC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS23 MDVLASYSIFQELQLVHDTGYFSALPSLEETWQQTCLELERYLQTEPRRISETFGEDLDC 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 FLHASPPPCIEESFRRLDPLLLPVEAAICEKSSAVDILLSRDKLLSETCLSLQPASSSLD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS23 FLHASPPPCIEESFRRLDPLLLPVEAAICEKSSAVDILLSRDKLLSETCLSLQPASSSLD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 SYTAVNQAQLNAVTSLTPPSSPELSRHLVKTSQTLSAVDGTVTLKLVAKKAALSSVKVGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS23 SYTAVNQAQLNAVTSLTPPSSPELSRHLVKTSQTLSAVDGTVTLKLVAKKAALSSVKVGG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 VATAAAAVTAAGAVKSGQSDSDQGGLGAEACPENKKRVHRCQFNGCRKVYTKSSHLKAHQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS23 VATAAAAVTAAGAVKSGQSDSDQGGLGAEACPENKKRVHRCQFNGCRKVYTKSSHLKAHQ 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 RTHTGEKPYKCSWEGCEWRFARSDELTRHYRKHTGAKPFKCNHCDRCFSRSDHLALHMKR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS23 RTHTGEKPYKCSWEGCEWRFARSDELTRHYRKHTGAKPFKCNHCDRCFSRSDHLALHMKR 250 260 270 280 290 300 pF1KB8 HI :: CCDS23 HI >>CCDS59438.1 KLF7 gene_id:8609|Hs108|chr2 (274 aa) initn: 1802 init1: 1802 opt: 1806 Z-score: 1126.1 bits: 216.3 E(32554): 2.1e-56 Smith-Waterman score: 1806; 98.9% identity (99.3% similar) in 272 aa overlap (31-302:4-274) 10 20 30 40 50 60 pF1KB8 MDVLASYSIFQELQLVHDTGYFSALPSLEETWQQTCLELERYLQTEPRRISETFGEDLDC .: :::::::::::::::::::::::::: CCDS59 MFPSWP-TCLELERYLQTEPRRISETFGEDLDC 10 20 30 70 80 90 100 110 120 pF1KB8 FLHASPPPCIEESFRRLDPLLLPVEAAICEKSSAVDILLSRDKLLSETCLSLQPASSSLD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS59 FLHASPPPCIEESFRRLDPLLLPVEAAICEKSSAVDILLSRDKLLSETCLSLQPASSSLD 40 50 60 70 80 90 130 140 150 160 170 180 pF1KB8 SYTAVNQAQLNAVTSLTPPSSPELSRHLVKTSQTLSAVDGTVTLKLVAKKAALSSVKVGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS59 SYTAVNQAQLNAVTSLTPPSSPELSRHLVKTSQTLSAVDGTVTLKLVAKKAALSSVKVGG 100 110 120 130 140 150 190 200 210 220 230 240 pF1KB8 VATAAAAVTAAGAVKSGQSDSDQGGLGAEACPENKKRVHRCQFNGCRKVYTKSSHLKAHQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS59 VATAAAAVTAAGAVKSGQSDSDQGGLGAEACPENKKRVHRCQFNGCRKVYTKSSHLKAHQ 160 170 180 190 200 210 250 260 270 280 290 300 pF1KB8 RTHTGEKPYKCSWEGCEWRFARSDELTRHYRKHTGAKPFKCNHCDRCFSRSDHLALHMKR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS59 RTHTGEKPYKCSWEGCEWRFARSDELTRHYRKHTGAKPFKCNHCDRCFSRSDHLALHMKR 220 230 240 250 260 270 pF1KB8 HI :: CCDS59 HI >>CCDS59440.1 KLF7 gene_id:8609|Hs108|chr2 (269 aa) initn: 1802 init1: 1802 opt: 1802 Z-score: 1123.8 bits: 215.8 E(32554): 2.8e-56 Smith-Waterman score: 1802; 100.0% identity (100.0% similar) in 268 aa overlap (35-302:2-269) 10 20 30 40 50 60 pF1KB8 ASYSIFQELQLVHDTGYFSALPSLEETWQQTCLELERYLQTEPRRISETFGEDLDCFLHA :::::::::::::::::::::::::::::: CCDS59 MTCLELERYLQTEPRRISETFGEDLDCFLHA 10 20 30 70 80 90 100 110 120 pF1KB8 SPPPCIEESFRRLDPLLLPVEAAICEKSSAVDILLSRDKLLSETCLSLQPASSSLDSYTA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS59 SPPPCIEESFRRLDPLLLPVEAAICEKSSAVDILLSRDKLLSETCLSLQPASSSLDSYTA 40 50 60 70 80 90 130 140 150 160 170 180 pF1KB8 VNQAQLNAVTSLTPPSSPELSRHLVKTSQTLSAVDGTVTLKLVAKKAALSSVKVGGVATA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS59 VNQAQLNAVTSLTPPSSPELSRHLVKTSQTLSAVDGTVTLKLVAKKAALSSVKVGGVATA 100 110 120 130 140 150 190 200 210 220 230 240 pF1KB8 AAAVTAAGAVKSGQSDSDQGGLGAEACPENKKRVHRCQFNGCRKVYTKSSHLKAHQRTHT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS59 AAAVTAAGAVKSGQSDSDQGGLGAEACPENKKRVHRCQFNGCRKVYTKSSHLKAHQRTHT 160 170 180 190 200 210 250 260 270 280 290 300 pF1KB8 GEKPYKCSWEGCEWRFARSDELTRHYRKHTGAKPFKCNHCDRCFSRSDHLALHMKRHI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS59 GEKPYKCSWEGCEWRFARSDELTRHYRKHTGAKPFKCNHCDRCFSRSDHLALHMKRHI 220 230 240 250 260 >>CCDS59439.1 KLF7 gene_id:8609|Hs108|chr2 (230 aa) initn: 1158 init1: 1136 opt: 1140 Z-score: 722.2 bits: 141.3 E(32554): 6.6e-34 Smith-Waterman score: 1140; 86.0% identity (91.6% similar) in 214 aa overlap (1-214:1-213) 10 20 30 40 50 60 pF1KB8 MDVLASYSIFQELQLVHDTGYFSALPSLEETWQQTCLELERYLQTEPRRISETFGEDLDC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS59 MDVLASYSIFQELQLVHDTGYFSALPSLEETWQQTCLELERYLQTEPRRISETFGEDLDC 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 FLHASPPPCIEESFRRLDPLLLPVEAAICEKSSAVDILLSRDKLLSETCLSLQPASSSLD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS59 FLHASPPPCIEESFRRLDPLLLPVEAAICEKSSAVDILLSRDKLLSETCLSLQPASSSLD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 SYTAVNQAQLNAVTSLTPPSSPELSRHLVKTSQTLSAVDGTVTLKLVAKKAALSSVKVGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::: . CCDS59 SYTAVNQAQLNAVTSLTPPSSPELSRHLVKTSQTLSAVDGTVTLKLVAKKAALSSVKVRS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 VATAAAAVTAAGAVKSGQSDSDQGGLGAEACPENKKRVHRCQFNGCRKVYTKSSHLKAHQ . .: . ..:... ..:. : : : CCDS59 LISAHGR-DVSGVLHEAMSSRGTTGNTQVQSPSNATTATGVFPGLTILPST 190 200 210 220 230 250 260 270 280 290 300 pF1KB8 RTHTGEKPYKCSWEGCEWRFARSDELTRHYRKHTGAKPFKCNHCDRCFSRSDHLALHMKR >>CCDS7060.1 KLF6 gene_id:1316|Hs108|chr10 (283 aa) initn: 1099 init1: 661 opt: 703 Z-score: 455.6 bits: 92.3 E(32554): 4.7e-19 Smith-Waterman score: 930; 51.0% identity (66.0% similar) in 312 aa overlap (1-302:1-283) 10 20 30 40 50 pF1KB8 MDVLASYSIFQELQLVHDTGYFSALPSLEETWQQTCLELERYLQTEPRRISET---FGED :::: :::::::.::.:::::::::::: :::::::::::::.:: .: . : . CCDS70 MDVLPMCSIFQELQIVHETGYFSALPSLEEYWQQTCLELERYLQSEPCYVSASEIKFDSQ 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB8 LDCFLHAS-PPPCIEESFRRL------DPLLLPVEAAICEKSSAVDILLSRDKLLSETCL : . . ::: .. : :. : : .: . . :... :: CCDS70 EDLWTKIILAREKKEESELKISSSPPEDTLISPSFCYNLETNSLNSDVSSESSDSSEELS 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB8 SLQPASSSLDSYTAVNQAQLNAVTSLTPPSSPELSRHLVKTSQTLSAVDGTVTLKLVAKK .:. . . :....:.. .. :::::::::: . :: . : : . CCDS70 PTAKFTSDPIGEVLVSSGKLSSSVTSTPPSSPELSR---EPSQLWGCVPGEL-------- 130 140 150 160 180 190 200 210 220 230 pF1KB8 AALSSVKVGGVATAAAAVTAAGAVKSGQSDSDQGGLGAEACPENKKRVHRCQFNGCRKVY . : :.:: : . ...: :....:::::.:::::::: CCDS70 ------------------PSPGKVRSGTSGKPGDKGNGDASPDGRRRVHRCHFNGCRKVY 170 180 190 200 210 240 250 260 270 280 290 pF1KB8 TKSSHLKAHQRTHTGEKPYKCSWEGCEWRFARSDELTRHYRKHTGAKPFKCNHCDRCFSR :::::::::::::::::::.:::::::::::::::::::.:::::::::::.:::::::: CCDS70 TKSSHLKAHQRTHTGEKPYRCSWEGCEWRFARSDELTRHFRKHTGAKPFKCSHCDRCFSR 220 230 240 250 260 270 300 pF1KB8 SDHLALHMKRHI :::::::::::. CCDS70 SDHLALHMKRHL 280 >>CCDS9449.1 KLF12 gene_id:11278|Hs108|chr13 (402 aa) initn: 691 init1: 546 opt: 567 Z-score: 371.2 bits: 77.2 E(32554): 2.4e-14 Smith-Waterman score: 567; 79.3% identity (92.4% similar) in 92 aa overlap (212-302:309-400) 190 200 210 220 230 240 pF1KB8 ATAAAAVTAAGAVKSGQSDSDQGGLGAEACPENKKR-VHRCQFNGCRKVYTKSSHLKAHQ :...:: .:::.:.:: ::::::::::::. CCDS94 RGNRMNNQKFPCSISPFSIESTRRQRRSESPDSRKRRIHRCDFEGCNKVYTKSSHLKAHR 280 290 300 310 320 330 250 260 270 280 290 300 pF1KB8 RTHTGEKPYKCSWEGCEWRFARSDELTRHYRKHTGAKPFKCNHCDRCFSRSDHLALHMKR :::::::::::.:::: :.::::::::::::::::.::::: ::: :::::::::: .: CCDS94 RTHTGEKPYKCTWEGCTWKFARSDELTRHYRKHTGVKPFKCADCDRSFSRSDHLALHRRR 340 350 360 370 380 390 pF1KB8 HI :. CCDS94 HMLV 400 >>CCDS66562.1 KLF5 gene_id:688|Hs108|chr13 (366 aa) initn: 579 init1: 559 opt: 559 Z-score: 366.8 bits: 76.2 E(32554): 4.1e-14 Smith-Waterman score: 559; 82.8% identity (93.1% similar) in 87 aa overlap (215-301:278-364) 190 200 210 220 230 240 pF1KB8 AAAVTAAGAVKSGQSDSDQGGLGAEACPENKKRVHRCQFNGCRKVYTKSSHLKAHQRTHT :.:.: :.. :: :::::::::::: :::: CCDS66 HNPNLPTTLPVNSQNIQPVRYNRRSNPDLEKRRIHYCDYPGCTKVYTKSSHLKAHLRTHT 250 260 270 280 290 300 250 260 270 280 290 300 pF1KB8 GEKPYKCSWEGCEWRFARSDELTRHYRKHTGAKPFKCNHCDRCFSRSDHLALHMKRHI :::::::.::::.::::::::::::::::::::::.:. :.: :::::::::::::: CCDS66 GEKPYKCTWEGCDWRFARSDELTRHYRKHTGAKPFQCGVCNRSFSRSDHLALHMKRHQN 310 320 330 340 350 360 >>CCDS3444.1 KLF3 gene_id:51274|Hs108|chr4 (345 aa) initn: 678 init1: 537 opt: 558 Z-score: 366.5 bits: 76.1 E(32554): 4.3e-14 Smith-Waterman score: 558; 77.8% identity (91.1% similar) in 90 aa overlap (213-302:254-343) 190 200 210 220 230 240 pF1KB8 TAAAAVTAAGAVKSGQSDSDQGGLGAEACPENKKRVHRCQFNGCRKVYTKSSHLKAHQRT . :.:.:::...:: ::::::::::::.:: CCDS34 SPPQALLQENHPSVIVQPGKRPLPVESPDTQRKRRIHRCDYDGCNKVYTKSSHLKAHRRT 230 240 250 260 270 280 250 260 270 280 290 300 pF1KB8 HTGEKPYKCSWEGCEWRFARSDELTRHYRKHTGAKPFKCNHCDRCFSRSDHLALHMKRHI :::::::::.:::: :.::::::::::.::::: :::.: ::: :::::::::: :::. CCDS34 HTGEKPYKCTWEGCTWKFARSDELTRHFRKHTGIKPFQCPDCDRSFSRSDHLALHRKRHM 290 300 310 320 330 340 CCDS34 LV >>CCDS9448.1 KLF5 gene_id:688|Hs108|chr13 (457 aa) initn: 559 init1: 559 opt: 559 Z-score: 365.7 bits: 76.3 E(32554): 4.8e-14 Smith-Waterman score: 559; 82.8% identity (93.1% similar) in 87 aa overlap (215-301:369-455) 190 200 210 220 230 240 pF1KB8 AAAVTAAGAVKSGQSDSDQGGLGAEACPENKKRVHRCQFNGCRKVYTKSSHLKAHQRTHT :.:.: :.. :: :::::::::::: :::: CCDS94 HNPNLPTTLPVNSQNIQPVRYNRRSNPDLEKRRIHYCDYPGCTKVYTKSSHLKAHLRTHT 340 350 360 370 380 390 250 260 270 280 290 300 pF1KB8 GEKPYKCSWEGCEWRFARSDELTRHYRKHTGAKPFKCNHCDRCFSRSDHLALHMKRHI :::::::.::::.::::::::::::::::::::::.:. :.: :::::::::::::: CCDS94 GEKPYKCTWEGCDWRFARSDELTRHYRKHTGAKPFQCGVCNRSFSRSDHLALHMKRHQN 400 410 420 430 440 450 >>CCDS14373.1 KLF8 gene_id:11279|Hs108|chrX (359 aa) initn: 570 init1: 527 opt: 537 Z-score: 353.5 bits: 73.7 E(32554): 2.3e-13 Smith-Waterman score: 537; 41.1% identity (69.0% similar) in 197 aa overlap (110-301:166-356) 80 90 100 110 120 130 pF1KB8 LLLPVEAAICEKSSAVDILLSRDKLLSETCLSLQPASSSLDSYTAVNQAQLNAVTSLTPP .:: ..: . .: :. . :.: CCDS14 PTVLTPGSVLTSSQSTGSQQILHVIHTIPSVSLPNKMGGLKTIPVVVQSLPMVYTTLPAD 140 150 160 170 180 190 140 150 160 170 180 190 pF1KB8 SSPELSRHLVKTSQTLSAVDGTVTLKLVAKKAALSSVKVGGVATAAAAVTAAGAVKSGQS ..: . . : . :: . .. . ...: ... . . .. ....:..: :. CCDS14 GGP------AAITVPLIGGDGKNAGSVKVDPTSMSPLEIPSDSEESTIESGSSALQSLQG 200 210 220 230 240 200 210 220 230 240 250 pF1KB8 DSDQGGL-----GAEACPENKKRVHRCQFNGCRKVYTKSSHLKAHQRTHTGEKPYKCSWE ... . : :. ...:.:.:.: :: ::::::::::::.: :::::::::.:. CCDS14 LQQEPAAMAQMQGEESLDLKRRRIHQCDFAGCSKVYTKSSHLKAHRRIHTGEKPYKCTWD 250 260 270 280 290 300 260 270 280 290 300 pF1KB8 GCEWRFARSDELTRHYRKHTGAKPFKCNHCDRCFSRSDHLALHMKRHI :: :.::::::::::.::::: :::.:. :.: :::::::.:: .:: CCDS14 GCSWKFARSDELTRHFRKHTGIKPFRCTDCNRSFSRSDHLSLHRRRHDTM 310 320 330 340 350 302 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 22:03:26 2016 done: Fri Nov 4 22:03:27 2016 Total Scan time: 2.820 Total Display time: 0.010 Function used was FASTA [36.3.4 Apr, 2011]