FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB8292, 449 aa 1>>>pF1KB8292 449 - 449 aa - 449 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 7.8774+/-0.000576; mu= 6.6539+/- 0.035 mean_var=328.7573+/-71.289, 0's: 0 Z-trim(115.4): 1975 B-trim: 1348 in 1/57 Lambda= 0.070735 statistics sampled from 23518 (25871) to 23518 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.656), E-opt: 0.2 (0.303), width: 16 Scan time: 6.260 The best scores are: opt bits E(85289) NP_001230633 (OMIM: 602126) zinc finger and BTB do ( 449) 3025 323.3 8.3e-88 NP_001137295 (OMIM: 602126) zinc finger and BTB do ( 449) 3025 323.3 8.3e-88 NP_003400 (OMIM: 602126) zinc finger and BTB domai ( 449) 3025 323.3 8.3e-88 NP_001230631 (OMIM: 602126) zinc finger and BTB do ( 449) 3025 323.3 8.3e-88 NP_872439 (OMIM: 616181) zinc finger protein 713 [ ( 443) 532 68.9 3.1e-11 NP_001177720 (OMIM: 613864) zinc finger protein 31 ( 563) 530 68.8 4.1e-11 NP_065984 (OMIM: 613864) zinc finger protein 317 i ( 595) 530 68.9 4.3e-11 XP_005259469 (OMIM: 604749) PREDICTED: zinc finger ( 734) 531 69.1 4.5e-11 NP_004225 (OMIM: 604749) zinc finger protein 235 [ ( 738) 531 69.1 4.5e-11 NP_001308284 (OMIM: 611024) zinc finger protein 66 ( 553) 520 67.8 8.3e-11 NP_001308285 (OMIM: 611024) zinc finger protein 66 ( 610) 520 67.8 8.8e-11 XP_011525511 (OMIM: 611024) PREDICTED: zinc finger ( 610) 520 67.8 8.8e-11 XP_011525510 (OMIM: 611024) PREDICTED: zinc finger ( 610) 520 67.8 8.8e-11 NP_071386 (OMIM: 611024) zinc finger protein 667 i ( 610) 520 67.8 8.8e-11 NP_001247415 (OMIM: 604086) zinc finger protein 15 ( 538) 519 67.7 8.8e-11 NP_001247416 (OMIM: 604086) zinc finger protein 15 ( 538) 519 67.7 8.8e-11 NP_932355 (OMIM: 604086) zinc finger protein 155 i ( 538) 519 67.7 8.8e-11 XP_005259272 (OMIM: 604086) PREDICTED: zinc finger ( 538) 519 67.7 8.8e-11 NP_003436 (OMIM: 604086) zinc finger protein 155 i ( 538) 519 67.7 8.8e-11 NP_001247417 (OMIM: 604086) zinc finger protein 15 ( 549) 519 67.7 8.9e-11 XP_016882737 (OMIM: 604086) PREDICTED: zinc finger ( 549) 519 67.7 8.9e-11 XP_011525580 (OMIM: 604086) PREDICTED: zinc finger ( 549) 519 67.7 8.9e-11 XP_011525581 (OMIM: 604086) PREDICTED: zinc finger ( 549) 519 67.7 8.9e-11 NP_001165697 (OMIM: 613903) zinc finger protein 54 ( 628) 511 66.9 1.7e-10 NP_689819 (OMIM: 613903) zinc finger protein 540 i ( 660) 511 67.0 1.7e-10 NP_001165696 (OMIM: 613903) zinc finger protein 54 ( 660) 511 67.0 1.7e-10 XP_016882236 (OMIM: 165260) PREDICTED: zinc finger ( 327) 504 65.8 1.9e-10 XP_011525220 (OMIM: 165260) PREDICTED: zinc finger ( 327) 504 65.8 1.9e-10 XP_011525219 (OMIM: 165260) PREDICTED: zinc finger ( 491) 504 66.1 2.4e-10 NP_862829 (OMIM: 165260) zinc finger and SCAN doma ( 491) 504 66.1 2.4e-10 NP_001308045 (OMIM: 165260) zinc finger and SCAN d ( 491) 504 66.1 2.4e-10 XP_006723255 (OMIM: 165260) PREDICTED: zinc finger ( 491) 504 66.1 2.4e-10 NP_066358 (OMIM: 194556) zinc finger protein 14 [H ( 642) 506 66.5 2.4e-10 XP_006716719 (OMIM: 194531) PREDICTED: zinc finger ( 590) 505 66.3 2.5e-10 XP_006716717 (OMIM: 194531) PREDICTED: zinc finger ( 590) 505 66.3 2.5e-10 XP_011515599 (OMIM: 194531) PREDICTED: zinc finger ( 590) 505 66.3 2.5e-10 NP_001269726 (OMIM: 194531) zinc finger protein 7 ( 590) 505 66.3 2.5e-10 XP_011513163 (OMIM: 602277) PREDICTED: zinc finger ( 675) 506 66.5 2.5e-10 NP_001305822 (OMIM: 602277) zinc finger protein 18 ( 675) 506 66.5 2.5e-10 XP_016881641 (OMIM: 604750) PREDICTED: zinc finger ( 502) 503 66.0 2.6e-10 XP_016881642 (OMIM: 604750) PREDICTED: zinc finger ( 502) 503 66.0 2.6e-10 NP_001305821 (OMIM: 602277) zinc finger protein 18 ( 751) 506 66.6 2.7e-10 NP_009080 (OMIM: 602277) zinc finger protein 184 i ( 751) 506 66.6 2.7e-10 NP_001305820 (OMIM: 602277) zinc finger protein 18 ( 751) 506 66.6 2.7e-10 XP_011515597 (OMIM: 194531) PREDICTED: zinc finger ( 685) 505 66.4 2.7e-10 XP_011515598 (OMIM: 194531) PREDICTED: zinc finger ( 685) 505 66.4 2.7e-10 XP_011515595 (OMIM: 194531) PREDICTED: zinc finger ( 686) 505 66.4 2.7e-10 NP_003407 (OMIM: 194531) zinc finger protein 7 iso ( 686) 505 66.4 2.7e-10 XP_011515596 (OMIM: 194531) PREDICTED: zinc finger ( 686) 505 66.4 2.7e-10 XP_011513317 (OMIM: 603978) PREDICTED: zinc finger ( 611) 504 66.2 2.7e-10 >>NP_001230633 (OMIM: 602126) zinc finger and BTB domain (449 aa) initn: 3025 init1: 3025 opt: 3025 Z-score: 1697.5 bits: 323.3 E(85289): 8.3e-88 Smith-Waterman score: 3025; 100.0% identity (100.0% similar) in 449 aa overlap (1-449:1-449) 10 20 30 40 50 60 pF1KB8 MEFFISMSETIKYNDDDHKTLFLKTLNEQRLEGEFCDIAIVVEDVKFRAHRCVLAACSTY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MEFFISMSETIKYNDDDHKTLFLKTLNEQRLEGEFCDIAIVVEDVKFRAHRCVLAACSTY 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 FKKLFKKLEVDSSSVIEIDFLRSDIFEEVLNYMYTAKISVKKEDVNLMMSSGQILGIRFL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FKKLFKKLEVDSSSVIEIDFLRSDIFEEVLNYMYTAKISVKKEDVNLMMSSGQILGIRFL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 DKLCSQKRDVSSPDENNGQSKSKYCLKINRPIGDAADTQDDDVEEIGDQDDSPSDDTVEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DKLCSQKRDVSSPDENNGQSKSKYCLKINRPIGDAADTQDDDVEEIGDQDDSPSDDTVEG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 TPPSQEDGKSPTTTLRVQEAILKELGSEEVRKVNCYGQEVESMETPESKDLGSQTPQALT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TPPSQEDGKSPTTTLRVQEAILKELGSEEVRKVNCYGQEVESMETPESKDLGSQTPQALT 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 FNDGMSEVKDEQTPGWTTAASDMKFEYLLYGHHREQIACQACGKTFSDEGRLRKHEKLHT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FNDGMSEVKDEQTPGWTTAASDMKFEYLLYGHHREQIACQACGKTFSDEGRLRKHEKLHT 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 ADRPFVCEMCTKGFTTQAHLKEHLKIHTGYKPYSCEVCGKSFIRAPDLKKHERVHSNERP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ADRPFVCEMCTKGFTTQAHLKEHLKIHTGYKPYSCEVCGKSFIRAPDLKKHERVHSNERP 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB8 FACHMCDKAFKHKSHLKDHERRHRGEKPFVCGSCTKAFAKASDLKRHENNMHSERKQVTP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FACHMCDKAFKHKSHLKDHERRHRGEKPFVCGSCTKAFAKASDLKRHENNMHSERKQVTP 370 380 390 400 410 420 430 440 pF1KB8 SAIQSETEQLQAAAMAAEAEQQLETIACS ::::::::::::::::::::::::::::: NP_001 SAIQSETEQLQAAAMAAEAEQQLETIACS 430 440 >>NP_001137295 (OMIM: 602126) zinc finger and BTB domain (449 aa) initn: 3025 init1: 3025 opt: 3025 Z-score: 1697.5 bits: 323.3 E(85289): 8.3e-88 Smith-Waterman score: 3025; 100.0% identity (100.0% similar) in 449 aa overlap (1-449:1-449) 10 20 30 40 50 60 pF1KB8 MEFFISMSETIKYNDDDHKTLFLKTLNEQRLEGEFCDIAIVVEDVKFRAHRCVLAACSTY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MEFFISMSETIKYNDDDHKTLFLKTLNEQRLEGEFCDIAIVVEDVKFRAHRCVLAACSTY 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 FKKLFKKLEVDSSSVIEIDFLRSDIFEEVLNYMYTAKISVKKEDVNLMMSSGQILGIRFL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FKKLFKKLEVDSSSVIEIDFLRSDIFEEVLNYMYTAKISVKKEDVNLMMSSGQILGIRFL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 DKLCSQKRDVSSPDENNGQSKSKYCLKINRPIGDAADTQDDDVEEIGDQDDSPSDDTVEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DKLCSQKRDVSSPDENNGQSKSKYCLKINRPIGDAADTQDDDVEEIGDQDDSPSDDTVEG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 TPPSQEDGKSPTTTLRVQEAILKELGSEEVRKVNCYGQEVESMETPESKDLGSQTPQALT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TPPSQEDGKSPTTTLRVQEAILKELGSEEVRKVNCYGQEVESMETPESKDLGSQTPQALT 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 FNDGMSEVKDEQTPGWTTAASDMKFEYLLYGHHREQIACQACGKTFSDEGRLRKHEKLHT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FNDGMSEVKDEQTPGWTTAASDMKFEYLLYGHHREQIACQACGKTFSDEGRLRKHEKLHT 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 ADRPFVCEMCTKGFTTQAHLKEHLKIHTGYKPYSCEVCGKSFIRAPDLKKHERVHSNERP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ADRPFVCEMCTKGFTTQAHLKEHLKIHTGYKPYSCEVCGKSFIRAPDLKKHERVHSNERP 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB8 FACHMCDKAFKHKSHLKDHERRHRGEKPFVCGSCTKAFAKASDLKRHENNMHSERKQVTP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FACHMCDKAFKHKSHLKDHERRHRGEKPFVCGSCTKAFAKASDLKRHENNMHSERKQVTP 370 380 390 400 410 420 430 440 pF1KB8 SAIQSETEQLQAAAMAAEAEQQLETIACS ::::::::::::::::::::::::::::: NP_001 SAIQSETEQLQAAAMAAEAEQQLETIACS 430 440 >>NP_003400 (OMIM: 602126) zinc finger and BTB domain-co (449 aa) initn: 3025 init1: 3025 opt: 3025 Z-score: 1697.5 bits: 323.3 E(85289): 8.3e-88 Smith-Waterman score: 3025; 100.0% identity (100.0% similar) in 449 aa overlap (1-449:1-449) 10 20 30 40 50 60 pF1KB8 MEFFISMSETIKYNDDDHKTLFLKTLNEQRLEGEFCDIAIVVEDVKFRAHRCVLAACSTY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 MEFFISMSETIKYNDDDHKTLFLKTLNEQRLEGEFCDIAIVVEDVKFRAHRCVLAACSTY 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 FKKLFKKLEVDSSSVIEIDFLRSDIFEEVLNYMYTAKISVKKEDVNLMMSSGQILGIRFL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 FKKLFKKLEVDSSSVIEIDFLRSDIFEEVLNYMYTAKISVKKEDVNLMMSSGQILGIRFL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 DKLCSQKRDVSSPDENNGQSKSKYCLKINRPIGDAADTQDDDVEEIGDQDDSPSDDTVEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 DKLCSQKRDVSSPDENNGQSKSKYCLKINRPIGDAADTQDDDVEEIGDQDDSPSDDTVEG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 TPPSQEDGKSPTTTLRVQEAILKELGSEEVRKVNCYGQEVESMETPESKDLGSQTPQALT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 TPPSQEDGKSPTTTLRVQEAILKELGSEEVRKVNCYGQEVESMETPESKDLGSQTPQALT 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 FNDGMSEVKDEQTPGWTTAASDMKFEYLLYGHHREQIACQACGKTFSDEGRLRKHEKLHT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 FNDGMSEVKDEQTPGWTTAASDMKFEYLLYGHHREQIACQACGKTFSDEGRLRKHEKLHT 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 ADRPFVCEMCTKGFTTQAHLKEHLKIHTGYKPYSCEVCGKSFIRAPDLKKHERVHSNERP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 ADRPFVCEMCTKGFTTQAHLKEHLKIHTGYKPYSCEVCGKSFIRAPDLKKHERVHSNERP 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB8 FACHMCDKAFKHKSHLKDHERRHRGEKPFVCGSCTKAFAKASDLKRHENNMHSERKQVTP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 FACHMCDKAFKHKSHLKDHERRHRGEKPFVCGSCTKAFAKASDLKRHENNMHSERKQVTP 370 380 390 400 410 420 430 440 pF1KB8 SAIQSETEQLQAAAMAAEAEQQLETIACS ::::::::::::::::::::::::::::: NP_003 SAIQSETEQLQAAAMAAEAEQQLETIACS 430 440 >>NP_001230631 (OMIM: 602126) zinc finger and BTB domain (449 aa) initn: 3025 init1: 3025 opt: 3025 Z-score: 1697.5 bits: 323.3 E(85289): 8.3e-88 Smith-Waterman score: 3025; 100.0% identity (100.0% similar) in 449 aa overlap (1-449:1-449) 10 20 30 40 50 60 pF1KB8 MEFFISMSETIKYNDDDHKTLFLKTLNEQRLEGEFCDIAIVVEDVKFRAHRCVLAACSTY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MEFFISMSETIKYNDDDHKTLFLKTLNEQRLEGEFCDIAIVVEDVKFRAHRCVLAACSTY 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 FKKLFKKLEVDSSSVIEIDFLRSDIFEEVLNYMYTAKISVKKEDVNLMMSSGQILGIRFL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FKKLFKKLEVDSSSVIEIDFLRSDIFEEVLNYMYTAKISVKKEDVNLMMSSGQILGIRFL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 DKLCSQKRDVSSPDENNGQSKSKYCLKINRPIGDAADTQDDDVEEIGDQDDSPSDDTVEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DKLCSQKRDVSSPDENNGQSKSKYCLKINRPIGDAADTQDDDVEEIGDQDDSPSDDTVEG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 TPPSQEDGKSPTTTLRVQEAILKELGSEEVRKVNCYGQEVESMETPESKDLGSQTPQALT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TPPSQEDGKSPTTTLRVQEAILKELGSEEVRKVNCYGQEVESMETPESKDLGSQTPQALT 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 FNDGMSEVKDEQTPGWTTAASDMKFEYLLYGHHREQIACQACGKTFSDEGRLRKHEKLHT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FNDGMSEVKDEQTPGWTTAASDMKFEYLLYGHHREQIACQACGKTFSDEGRLRKHEKLHT 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 ADRPFVCEMCTKGFTTQAHLKEHLKIHTGYKPYSCEVCGKSFIRAPDLKKHERVHSNERP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ADRPFVCEMCTKGFTTQAHLKEHLKIHTGYKPYSCEVCGKSFIRAPDLKKHERVHSNERP 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB8 FACHMCDKAFKHKSHLKDHERRHRGEKPFVCGSCTKAFAKASDLKRHENNMHSERKQVTP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FACHMCDKAFKHKSHLKDHERRHRGEKPFVCGSCTKAFAKASDLKRHENNMHSERKQVTP 370 380 390 400 410 420 430 440 pF1KB8 SAIQSETEQLQAAAMAAEAEQQLETIACS ::::::::::::::::::::::::::::: NP_001 SAIQSETEQLQAAAMAAEAEQQLETIACS 430 440 >>NP_872439 (OMIM: 616181) zinc finger protein 713 [Homo (443 aa) initn: 1104 init1: 493 opt: 532 Z-score: 322.6 bits: 68.9 E(85289): 3.1e-11 Smith-Waterman score: 532; 37.8% identity (73.5% similar) in 196 aa overlap (224-416:232-424) 200 210 220 230 240 250 pF1KB8 TLRVQEAILKELGSEEVRKVNCYGQEVESMETP-ESKDLGSQTPQALTFNDGM--SEVKD ::: : .. :. : . ..: . .: . NP_872 SIKIPLNSDTQGNSIKHNSDLIYYQGNYVRETPYEYSECGKIFNQHILLTDHIHTAEKPS 210 220 230 240 250 260 260 270 280 290 300 310 pF1KB8 EQTPGWTTAASDMKFEYLLYGHHREQIACQACGKTFSDEGRLRKHEKLHTADRPFVCEMC : ... ..: . ..:: :. . :. ::: ::.. .: .:...::...::.:. : NP_872 ECGKAFSHTSSLSQPQMLLTGE--KPYKCDECGKRFSQRIHLIQHQRIHTGEKPFICNGC 270 280 290 300 310 320 330 340 350 360 370 pF1KB8 TKGFTTQAHLKEHLKIHTGYKPYSCEVCGKSFIRAPDLKKHERVHSNERPFACHMCDKAF :.: .. . .::.:::: :::.:. :::.: : .: .:.:.:..:.:. : .: ::: NP_872 GKAFRQHSSFTQHLRIHTGEKPYKCNQCGKAFSRITSLTEHHRLHTGEKPYECGFCGKAF 320 330 340 350 360 370 380 390 400 410 420 430 pF1KB8 KHKSHLKDHERRHRGEKPFVCGSCTKAFAKASDLKRHENNMHSERKQVTPSAIQSETEQL ....::..::: : ::::. :. : :::.... :..:.. .:...: NP_872 SQRTHLNQHERTHTGEKPYKCNECGKAFSQSAHLNQHRK-IHTREKLCEYKCEQTVRHSP 380 390 400 410 420 430 440 pF1KB8 QAAAMAAEAEQQLETIACS NP_872 SFSST 440 >>NP_001177720 (OMIM: 613864) zinc finger protein 317 is (563 aa) initn: 1941 init1: 489 opt: 530 Z-score: 320.4 bits: 68.8 E(85289): 4.1e-11 Smith-Waterman score: 530; 40.9% identity (68.5% similar) in 181 aa overlap (237-415:179-356) 210 220 230 240 250 260 pF1KB8 SEEVRKVNCYGQEVESMETPESKDLGSQTPQALTFNDG--MSEVKDEQTPGWTTAASDMK : ... :: : : .. : ..::.:: . NP_001 LTQPMGRHAGKRPYHRRDYGVAFKGRPHLTQHMSMYDGRKMHECHQCQK-AFTTSASLTR 150 160 170 180 190 200 270 280 290 300 310 320 pF1KB8 FEYLLYGHHREQIACQACGKTFSDEGRLRKHEKLHTADRPFVCEMCTKGFTTQAHLKEHL . . :. . :. :::.:.: . ::.: . : ..:: : .: ..: : . :: :. NP_001 HRRIHTGE--KPYECSDCGKAFNDPSALRSHARTHLKEKPFDCSQCGNAFRTLSALKIHM 210 220 230 240 250 260 330 340 350 360 370 380 pF1KB8 KIHTGYKPYSCEVCGKSFIRAPDLKKHERVHSNERPFACHMCDKAFKHKSHLKDHERRHR ..::: .::.:. :::.. :. : :.:.:..:::. :: : :::.: ::::.: : : NP_001 RVHTGERPYKCDQCGKAYGRSCHLIAHKRTHTGERPYECHDCGKAFQHPSHLKEHVRNHT 270 280 290 300 310 320 390 400 410 420 430 440 pF1KB8 GEKPFVCGSCTKAFAKASDLKRHENNMHSERKQVTPSAIQSETEQLQAAAMAAEAEQQLE ::::..: .: ::: :... :..: :. NP_001 GEKPYACTQCGKAFRWKSNFNLHKKNHMVEKTYECKECGKSFGDLVSRRKHMRIHIVKKP 330 340 350 360 370 380 pF1KB8 TIACS NP_001 VECRQCGKTFRNQSILKTHMNSHTGEKPYGCDLCGKAFSASSNLTAHRKIHTQERRYECA 390 400 410 420 430 440 >-- initn: 1110 init1: 393 opt: 416 Z-score: 257.5 bits: 57.2 E(85289): 1.3e-07 Smith-Waterman score: 416; 38.5% identity (67.8% similar) in 143 aa overlap (274-416:383-524) 250 260 270 280 290 300 pF1KB8 GMSEVKDEQTPGWTTAASDMKFEYLLYGHHREQIACQACGKTFSDEGRLRKHEKLHTADR .. . :. ::::: ... :. : . ::... NP_001 MVEKTYECKECGKSFGDLVSRRKHMRIHIVKKPVECRQCGKTFRNQSILKTHMNSHTGEK 360 370 380 390 400 410 310 320 330 340 350 360 pF1KB8 PFVCEMCTKGFTTQAHLKEHLKIHTGYKPYSCEVCGKSFIRAPDLKKHERVHSNERPFAC :. :..: :.:.....: : :::: . : : .::: : . ..: :: .. : NP_001 PYGCDLCGKAFSASSNLTAHRKIHTQERRYECAACGKVFGDYLSRRRHMSVHLVKKRVEC 420 430 440 450 460 470 370 380 390 400 410 420 pF1KB8 HMCDKAFKHKSHLKDHERRHRGEKPFVCGSCTKAFAKASDLKRHENNMHSERKQVTPSAI ..: :::...: :: : : : ::::. : : :::. .:.:. :. .:. .: NP_001 RQCGKAFRNQSTLKTHMRSHTGEKPYECDHCGKAFSIGSNLNVHRR-IHTGEKPYECLVC 480 490 500 510 520 530 430 440 pF1KB8 QSETEQLQAAAMAAEAEQQLETIACS NP_001 GKAFSDHSSLRSHVKTHRGEKLFVSSVWKRLQ 540 550 560 >>NP_065984 (OMIM: 613864) zinc finger protein 317 isofo (595 aa) initn: 1941 init1: 489 opt: 530 Z-score: 320.2 bits: 68.9 E(85289): 4.3e-11 Smith-Waterman score: 537; 31.4% identity (61.0% similar) in 315 aa overlap (125-415:77-388) 100 110 120 130 140 150 pF1KB8 TAKISVKKEDVNLMMSSGQILGIRFLDKLCSQKRDVSSPDENNGQSKSKYCLKINRP--I ::.. .. .: .. .. ....: : NP_065 HTPSVGSQESVTFQDVAVDFTEKEWPLLDSSQRKLYKDVMLENYSNLTSLGYQVGKPSLI 50 60 70 80 90 100 160 170 180 190 200 pF1KB8 GDAADTQDDDVEEIGDQDDSPSD-DTVEGTPPS--QED--GKSPTTTLRVQEAILKELGS . . .. .:: : .. . .: .: : : .:: :: . . ...: : : .. NP_065 SHLEQEEEPRTEERGAHQGACADWETPSKTKWSLLMEDIFGKETPSGVTMERAGLGEKST 110 120 130 140 150 160 210 220 230 240 250 pF1KB8 EEVRKVNCYGQE---VESM-----ETP-ESKDLG------SQTPQALTFNDG--MSEVKD : .. . .:.. .. : . : . .: : . : ... :: : : .. NP_065 EYAHLFEVFGMDPHLTQPMGRHAGKRPYHRRDYGVAFKGRPHLTQHMSMYDGRKMHECHQ 170 180 190 200 210 220 260 270 280 290 300 310 pF1KB8 EQTPGWTTAASDMKFEYLLYGHHREQIACQACGKTFSDEGRLRKHEKLHTADRPFVCEMC : ..::.:: . . . : .. :. :::.:.: . ::.: . : ..:: : .: NP_065 CQK-AFTTSASLTRHRRIHTG--EKPYECSDCGKAFNDPSALRSHARTHLKEKPFDCSQC 230 240 250 260 270 280 320 330 340 350 360 370 pF1KB8 TKGFTTQAHLKEHLKIHTGYKPYSCEVCGKSFIRAPDLKKHERVHSNERPFACHMCDKAF ..: : . :: :...::: .::.:. :::.. :. : :.:.:..:::. :: : ::: NP_065 GNAFRTLSALKIHMRVHTGERPYKCDQCGKAYGRSCHLIAHKRTHTGERPYECHDCGKAF 290 300 310 320 330 340 380 390 400 410 420 430 pF1KB8 KHKSHLKDHERRHRGEKPFVCGSCTKAFAKASDLKRHENNMHSERKQVTPSAIQSETEQL .: ::::.: : : ::::..: .: ::: :... :..: :. NP_065 QHPSHLKEHVRNHTGEKPYACTQCGKAFRWKSNFNLHKKNHMVEKTYECKECGKSFGDLV 350 360 370 380 390 400 440 pF1KB8 QAAAMAAEAEQQLETIACS NP_065 SRRKHMRIHIVKKPVECRQCGKTFRNQSILKTHMNSHTGEKPYGCDLCGKAFSASSNLTA 410 420 430 440 450 460 >-- initn: 1110 init1: 393 opt: 416 Z-score: 257.3 bits: 57.2 E(85289): 1.4e-07 Smith-Waterman score: 416; 38.5% identity (67.8% similar) in 143 aa overlap (274-416:415-556) 250 260 270 280 290 300 pF1KB8 GMSEVKDEQTPGWTTAASDMKFEYLLYGHHREQIACQACGKTFSDEGRLRKHEKLHTADR .. . :. ::::: ... :. : . ::... NP_065 MVEKTYECKECGKSFGDLVSRRKHMRIHIVKKPVECRQCGKTFRNQSILKTHMNSHTGEK 390 400 410 420 430 440 310 320 330 340 350 360 pF1KB8 PFVCEMCTKGFTTQAHLKEHLKIHTGYKPYSCEVCGKSFIRAPDLKKHERVHSNERPFAC :. :..: :.:.....: : :::: . : : .::: : . ..: :: .. : NP_065 PYGCDLCGKAFSASSNLTAHRKIHTQERRYECAACGKVFGDYLSRRRHMSVHLVKKRVEC 450 460 470 480 490 500 370 380 390 400 410 420 pF1KB8 HMCDKAFKHKSHLKDHERRHRGEKPFVCGSCTKAFAKASDLKRHENNMHSERKQVTPSAI ..: :::...: :: : : : ::::. : : :::. .:.:. :. .:. .: NP_065 RQCGKAFRNQSTLKTHMRSHTGEKPYECDHCGKAFSIGSNLNVHRR-IHTGEKPYECLVC 510 520 530 540 550 560 430 440 pF1KB8 QSETEQLQAAAMAAEAEQQLETIACS NP_065 GKAFSDHSSLRSHVKTHRGEKLFVSSVWKRLQ 570 580 590 >>XP_005259469 (OMIM: 604749) PREDICTED: zinc finger pro (734 aa) initn: 3624 init1: 505 opt: 531 Z-score: 319.8 bits: 69.1 E(85289): 4.5e-11 Smith-Waterman score: 548; 34.6% identity (60.5% similar) in 286 aa overlap (139-416:198-453) 110 120 130 140 150 160 pF1KB8 MSSGQILGIRFLDKLCSQKRDVSSPDENNGQSKSKYCLKINRPIGDA----ADTQDDDVE : :.: : : : : . .::.. XP_005 QEFPTGKVPNSWSKIYLNETQNYQRSCKQTQMKNKLC--IFAPYVDIFSCISHHHDDNIV 170 180 190 200 210 220 170 180 190 200 210 220 pF1KB8 EIGDQDDSPSD---DTVEGTPPSQEDGKSPTTTLRVQEAILKELGSEEVRKVNCYGQEVE . :. : :: ::.. .: .:.. .. : . :.: . : . XP_005 HKRDKVHSNSDCGKDTLKVSPLTQRSIHTGQKTYQ---------GNECEEAFN----DSS 230 240 250 260 270 230 240 250 260 270 280 pF1KB8 SMETPESKDLGSQTPQALTFNDGMSEVKDEQTPGWTTAASDMKFEYLLY-GHHREQIACQ :.: .. ::...: : . :: :. .: . . . :..: :. XP_005 SLELHKQVHLGKKSPACSTHE------KD------TSYSSGIPVQQSVRTGKKRYW--CH 280 290 300 310 290 300 310 320 330 340 pF1KB8 ACGKTFSDEGRLRKHEKLHTADRPFVCEMCTKGFTTQAHLKEHLKIHTGYKPYSCEVCGK ::: ::. . :. :...::...:..:. : :.:. ..:: :: :::: ::: :. ::: XP_005 ECGKGFSQSSNLQTHQRVHTGEKPYTCHECGKSFNQSSHLYAHLPIHTGEKPYRCDSCGK 320 330 340 350 360 370 350 360 370 380 390 400 pF1KB8 SFIRAPDLKKHERVHSNERPFACHMCDKAFKHKSHLKDHERRHRGEKPFVCGSCTKAFAK .: :. ::. : :::..:.:. :..: :.: ..:::. ::: : ::::. ::.: : :. XP_005 GFSRSTDLNIHCRVHTGEKPYKCEVCGKGFTQRSHLQAHERIHTGEKPYKCGDCGKRFSC 380 390 400 410 420 430 410 420 430 440 pF1KB8 ASDLKRHENNMHSERKQVTPSAIQSETEQLQAAAMAAEAEQQLETIACS .:.:. :. .:.:.: XP_005 SSNLHTHQR-VHTEEKPYKCDECGKCFSLSFNLHSHQRVHTGEKPYKCEECGKGFSSASS 440 450 460 470 480 490 >-- initn: 2543 init1: 482 opt: 506 Z-score: 306.0 bits: 66.5 E(85289): 2.6e-10 Smith-Waterman score: 509; 36.9% identity (68.4% similar) in 187 aa overlap (269-448:470-656) 240 250 260 270 280 290 pF1KB8 LTFNDGMSEVKDEQTPGWTTAASDMKFEYLLYGHHR-----EQIACQACGKTFSDEGRLR :..:.: . :. ::: ::. . .. XP_005 SNLHTHQRVHTEEKPYKCDECGKCFSLSFNLHSHQRVHTGEKPYKCEECGKGFSSASSFQ 440 450 460 470 480 490 300 310 320 330 340 350 pF1KB8 KHEKLHTADRPFVCEMCTKGFTTQAHLKEHLKIHTGYKPYSCEVCGKSFIRAPDLKKHER .:...::...:: :..: :::. ..... : ..::: :::.:::::: : . .:..:.: XP_005 SHQRVHTGEKPFRCNVCGKGFSQSSYFQAHQRVHTGEKPYKCEVCGKRFNWSLNLHNHQR 500 510 520 530 540 550 360 370 380 390 400 410 pF1KB8 VHSNERPFACHMCDKAFKHKSHLKDHERRHRGEKPFVCGSCTKAFAKASDLKRHENNMHS ::..:.:. :. : :.:.. :.:. :. : ::::: : .: : :..:: :. :. . XP_005 VHTGEKPYKCEECGKGFSQASNLQAHQSVHTGEKPFKCDACQKRFSQASHLQAHQRVHTG 560 570 580 590 600 610 420 430 440 pF1KB8 ER--KQVTPSAIQSETEQLQAAAMAAEAEQQLETIACS :. : : . :. .::. . .:. .. : XP_005 EKPYKCDTCGKAFSQRSNLQVHQIIHTGEKPFKCEECGKEFSWSAGLSAHQRVHTGEKPY 620 630 640 650 660 670 XP_005 TCQQCGKGFSQASHFHTHQRVHTGERPYICDVCCKGFSQRSHLIYHQRVHTGGNL 680 690 700 710 720 730 >>NP_004225 (OMIM: 604749) zinc finger protein 235 [Homo (738 aa) initn: 3624 init1: 505 opt: 531 Z-score: 319.8 bits: 69.1 E(85289): 4.5e-11 Smith-Waterman score: 548; 34.6% identity (60.5% similar) in 286 aa overlap (139-416:202-457) 110 120 130 140 150 160 pF1KB8 MSSGQILGIRFLDKLCSQKRDVSSPDENNGQSKSKYCLKINRPIGDA----ADTQDDDVE : :.: : : : : . .::.. NP_004 QEFPTGKVPNSWSKIYLNETQNYQRSCKQTQMKNKLC--IFAPYVDIFSCISHHHDDNIV 180 190 200 210 220 170 180 190 200 210 220 pF1KB8 EIGDQDDSPSD---DTVEGTPPSQEDGKSPTTTLRVQEAILKELGSEEVRKVNCYGQEVE . :. : :: ::.. .: .:.. .. : . :.: . : . NP_004 HKRDKVHSNSDCGKDTLKVSPLTQRSIHTGQKTYQ---------GNECEEAFN----DSS 230 240 250 260 270 230 240 250 260 270 280 pF1KB8 SMETPESKDLGSQTPQALTFNDGMSEVKDEQTPGWTTAASDMKFEYLLY-GHHREQIACQ :.: .. ::...: : . :: :. .: . . . :..: :. NP_004 SLELHKQVHLGKKSPACSTHE------KD------TSYSSGIPVQQSVRTGKKRYW--CH 280 290 300 310 320 290 300 310 320 330 340 pF1KB8 ACGKTFSDEGRLRKHEKLHTADRPFVCEMCTKGFTTQAHLKEHLKIHTGYKPYSCEVCGK ::: ::. . :. :...::...:..:. : :.:. ..:: :: :::: ::: :. ::: NP_004 ECGKGFSQSSNLQTHQRVHTGEKPYTCHECGKSFNQSSHLYAHLPIHTGEKPYRCDSCGK 330 340 350 360 370 380 350 360 370 380 390 400 pF1KB8 SFIRAPDLKKHERVHSNERPFACHMCDKAFKHKSHLKDHERRHRGEKPFVCGSCTKAFAK .: :. ::. : :::..:.:. :..: :.: ..:::. ::: : ::::. ::.: : :. NP_004 GFSRSTDLNIHCRVHTGEKPYKCEVCGKGFTQRSHLQAHERIHTGEKPYKCGDCGKRFSC 390 400 410 420 430 440 410 420 430 440 pF1KB8 ASDLKRHENNMHSERKQVTPSAIQSETEQLQAAAMAAEAEQQLETIACS .:.:. :. .:.:.: NP_004 SSNLHTHQR-VHTEEKPYKCDECGKCFSLSFNLHSHQRVHTGEKPYKCEECGKGFSSASS 450 460 470 480 490 500 >-- initn: 2543 init1: 482 opt: 506 Z-score: 306.0 bits: 66.5 E(85289): 2.6e-10 Smith-Waterman score: 509; 36.9% identity (68.4% similar) in 187 aa overlap (269-448:474-660) 240 250 260 270 280 290 pF1KB8 LTFNDGMSEVKDEQTPGWTTAASDMKFEYLLYGHHR-----EQIACQACGKTFSDEGRLR :..:.: . :. ::: ::. . .. NP_004 SNLHTHQRVHTEEKPYKCDECGKCFSLSFNLHSHQRVHTGEKPYKCEECGKGFSSASSFQ 450 460 470 480 490 500 300 310 320 330 340 350 pF1KB8 KHEKLHTADRPFVCEMCTKGFTTQAHLKEHLKIHTGYKPYSCEVCGKSFIRAPDLKKHER .:...::...:: :..: :::. ..... : ..::: :::.:::::: : . .:..:.: NP_004 SHQRVHTGEKPFRCNVCGKGFSQSSYFQAHQRVHTGEKPYKCEVCGKRFNWSLNLHNHQR 510 520 530 540 550 560 360 370 380 390 400 410 pF1KB8 VHSNERPFACHMCDKAFKHKSHLKDHERRHRGEKPFVCGSCTKAFAKASDLKRHENNMHS ::..:.:. :. : :.:.. :.:. :. : ::::: : .: : :..:: :. :. . NP_004 VHTGEKPYKCEECGKGFSQASNLQAHQSVHTGEKPFKCDACQKRFSQASHLQAHQRVHTG 570 580 590 600 610 620 420 430 440 pF1KB8 ER--KQVTPSAIQSETEQLQAAAMAAEAEQQLETIACS :. : : . :. .::. . .:. .. : NP_004 EKPYKCDTCGKAFSQRSNLQVHQIIHTGEKPFKCEECGKEFSWSAGLSAHQRVHTGEKPY 630 640 650 660 670 680 NP_004 TCQQCGKGFSQASHFHTHQRVHTGERPYICDVCCKGFSQRSHLIYHQRVHTGGNL 690 700 710 720 730 >>NP_001308284 (OMIM: 611024) zinc finger protein 667 is (553 aa) initn: 1862 init1: 497 opt: 520 Z-score: 315.0 bits: 67.8 E(85289): 8.3e-11 Smith-Waterman score: 520; 47.8% identity (76.8% similar) in 138 aa overlap (279-416:416-552) 250 260 270 280 290 300 pF1KB8 KDEQTPGWTTAASDMKFEYLLYGHHREQIACQACGKTFSDEGRLRKHEKLHTADRPFVCE :. :::.:: . : .:...:: :::. :. NP_001 FKCNKCSKVFGRQSFLIEHQRIHTGEKPYQCEECGKAFSHRISLTRHKRIHTEDRPYECD 390 400 410 420 430 440 310 320 330 340 350 360 pF1KB8 MCTKGFTTQAHLKEHLKIHTGYKPYSCEVCGKSFIRAPDLKKHERVHSNERPFACHMCDK .: :.:. .::: .: .:::: :::.:..:::.: . .: ::: :..:.:. :. : : NP_001 QCGKAFSQSAHLAQHERIHTGEKPYTCKTCGKAFSQRTSLILHERSHTGEKPYECNECGK 450 460 470 480 490 500 370 380 390 400 410 420 pF1KB8 AFKHKSHLKDHERRHRGEKPFVCGSCTKAFAKASDLKRHENNMHSERKQVTPSAIQSETE ::. : : :.: : .:::. :..: ::....:.: ::.:. :::.: NP_001 AFSSGSDLIRHQRSHSSEKPYECSKCGKAYSRSSSLIRHQNT-HSEEKA 510 520 530 540 550 430 440 pF1KB8 QLQAAAMAAEAEQQLETIACS >-- initn: 679 init1: 250 opt: 309 Z-score: 198.6 bits: 46.3 E(85289): 0.00025 Smith-Waterman score: 309; 32.7% identity (61.9% similar) in 147 aa overlap (271-416:80-222) 250 260 270 280 290 pF1KB8 FNDGMSEVKDEQTPGWTTAASDMKFEYLLYGHH-REQIACQACGKTFSDEGRLRKHEKLH :: .. . :. :::::: :. :...: NP_001 ICQKLVSAQQKAPTRKSGCNKNSVLVKPKKGHSGKKPLKCNDCGKTFSRSFSLKLHQNIH 50 60 70 80 90 100 300 310 320 330 340 350 pF1KB8 TADRPFVCEMCTKGFTTQAHLKEHLKIHTGYKPYSCEVCGKSFIRAPDLKKHERVHSNER :...:: : : :.: . . : .::.: : . :. ::.:: . : : :.:.... NP_001 TGEKPFECSNCRKAFRQISSILLHQRIHSGKKSHECNKCGESFNQRTTLILHMRIHDGKE 110 120 130 140 150 160 360 370 380 390 400 410 pF1KB8 PFACHMCDKAFKHKSHLKDHERRHRGEKPFVCGSCTKAFAKASDLKRHENNMHSERKQVT . : ::... . .. :.. : . : .: ::: . :.: :.. .:. .: NP_001 ILD---CGKALSQCQSFNIHQKIHVVGNVCQCRKCGKAFNQMSSLLLHKK-IHNGKKTHK 170 180 190 200 210 220 420 430 440 pF1KB8 PSAIQSETEQLQAAAMAAEAEQQLETIACS NP_001 YNKCGRGFKKKSVFVVHKRIHAGEKIPENAKALSQSLQQRSHHLENPFKCRKCGKLFNRI 230 240 250 260 270 280 >-- initn: 628 init1: 238 opt: 309 Z-score: 198.6 bits: 46.3 E(85289): 0.00025 Smith-Waterman score: 376; 37.4% identity (65.3% similar) in 147 aa overlap (272-416:267-412) 250 260 270 280 290 300 pF1KB8 NDGMSEVKDEQTPGWTTAASDMKFEYLLYGHHREQ-IACQACGKTFSDEGRLRKHEKLHT :: :. . :. ::: :. . : :...:: NP_001 SVFVVHKRIHAGEKIPENAKALSQSLQQRSHHLENPFKCRKCGKLFNRISPLMLHQRIHT 240 250 260 270 280 290 310 320 330 340 350 360 pF1KB8 ADRPFVCEMCTKGFTTQAHLKEHLKIHTGYKPYSCEVCGKSFIRAPDLKKHERVHSNERP ...:. :. : : : . : ::.::.: : : :. : : : .: .:..::.... NP_001 SEKPYKCDKCDKFFRRLSTLILHLRIHNGEKLYRCNKCEKVCNRHSSLIQHQKVHTKKKK 300 310 320 330 340 350 370 380 390 400 410 pF1KB8 -FACHMCDKAFKHKSHLKDHERRHRGEKPFVCGSCTKAFAKASDLKRHENNMHSERKQVT : :. : : :. ..:: :. : :::: :..:.:.:.. : : .:. .:. .: NP_001 LFECKECGKMFSGTANLKIHQNIHSEEKPFKCNKCSKVFGRQSFLIEHQR-IHTGEKPYQ 360 370 380 390 400 410 420 430 440 pF1KB8 PSAIQSETEQLQAAAMAAEAEQQLETIACS NP_001 CEECGKAFSHRISLTRHKRIHTEDRPYECDQCGKAFSQSAHLAQHERIHTGEKPYTCKTC 420 430 440 450 460 470 449 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 11:27:02 2016 done: Fri Nov 4 11:27:03 2016 Total Scan time: 6.260 Total Display time: 0.030 Function used was FASTA [36.3.4 Apr, 2011]