FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB8295, 473 aa 1>>>pF1KB8295 473 - 473 aa - 473 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 7.2152+/-0.000383; mu= 10.8534+/- 0.024 mean_var=257.2641+/-54.047, 0's: 0 Z-trim(120.3): 1953 B-trim: 127 in 1/58 Lambda= 0.079962 statistics sampled from 33124 (35416) to 33124 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.752), E-opt: 0.2 (0.415), width: 16 Scan time: 5.980 The best scores are: opt bits E(85289) XP_005250625 (OMIM: 601261) PREDICTED: zinc finger ( 473) 3321 396.6 7.8e-110 NP_666019 (OMIM: 601261) zinc finger and SCAN doma ( 473) 3321 396.6 7.8e-110 XP_006716176 (OMIM: 601261) PREDICTED: zinc finger ( 473) 3321 396.6 7.8e-110 XP_016868073 (OMIM: 601261) PREDICTED: zinc finger ( 473) 3321 396.6 7.8e-110 XP_016868074 (OMIM: 601261) PREDICTED: zinc finger ( 450) 1784 219.3 1.8e-56 XP_016866753 (OMIM: 616474) PREDICTED: zinc finger ( 478) 1114 142.0 3.4e-33 NP_001104509 (OMIM: 616474) zinc finger and SCAN d ( 478) 1114 142.0 3.4e-33 XP_016866748 (OMIM: 600834) PREDICTED: zinc finger ( 485) 1110 141.6 4.8e-33 XP_016866747 (OMIM: 600834) PREDICTED: zinc finger ( 485) 1110 141.6 4.8e-33 XP_016866749 (OMIM: 600834) PREDICTED: zinc finger ( 485) 1110 141.6 4.8e-33 NP_003438 (OMIM: 600834) zinc finger protein 165 [ ( 485) 1110 141.6 4.8e-33 XP_011513177 (OMIM: 602246) PREDICTED: zinc finger ( 583) 998 128.8 4.1e-29 NP_689908 (OMIM: 300627) zinc finger protein 449 [ ( 518) 957 123.9 1e-27 XP_011529614 (OMIM: 300627) PREDICTED: zinc finger ( 518) 957 123.9 1e-27 NP_001276331 (OMIM: 604077) zinc finger protein 13 ( 616) 958 124.2 1e-27 XP_016882731 (OMIM: 604077) PREDICTED: zinc finger ( 621) 958 124.2 1e-27 XP_016882730 (OMIM: 604077) PREDICTED: zinc finger ( 628) 958 124.2 1e-27 XP_016882729 (OMIM: 604077) PREDICTED: zinc finger ( 658) 958 124.2 1.1e-27 NP_001276330 (OMIM: 604077) zinc finger protein 13 ( 658) 958 124.2 1.1e-27 XP_006723425 (OMIM: 604077) PREDICTED: zinc finger ( 670) 958 124.2 1.1e-27 XP_005259268 (OMIM: 604077) PREDICTED: zinc finger ( 670) 958 124.2 1.1e-27 XP_006723426 (OMIM: 604077) PREDICTED: zinc finger ( 670) 958 124.2 1.1e-27 NP_003427 (OMIM: 604077) zinc finger protein 135 i ( 670) 958 124.2 1.1e-27 NP_009065 (OMIM: 604077) zinc finger protein 135 i ( 682) 958 124.2 1.1e-27 XP_011513176 (OMIM: 602240) PREDICTED: zinc finger ( 391) 932 120.9 6.4e-27 NP_001265050 (OMIM: 602240) zinc finger protein wi ( 391) 932 120.9 6.4e-27 NP_001265051 (OMIM: 602240) zinc finger protein wi ( 391) 932 120.9 6.4e-27 XP_011513175 (OMIM: 602240) PREDICTED: zinc finger ( 391) 932 120.9 6.4e-27 XP_016866755 (OMIM: 602240) PREDICTED: zinc finger ( 578) 932 121.1 8e-27 XP_011513172 (OMIM: 602240) PREDICTED: zinc finger ( 578) 932 121.1 8e-27 NP_006289 (OMIM: 602240) zinc finger protein with ( 578) 932 121.1 8e-27 NP_001265048 (OMIM: 602240) zinc finger protein wi ( 578) 932 121.1 8e-27 XP_016885222 (OMIM: 300573) PREDICTED: zinc finger ( 513) 925 120.3 1.3e-26 XP_016885221 (OMIM: 300573) PREDICTED: zinc finger ( 513) 925 120.3 1.3e-26 XP_011542247 (OMIM: 300573) PREDICTED: zinc finger ( 514) 925 120.3 1.3e-26 XP_016885219 (OMIM: 300573) PREDICTED: zinc finger ( 514) 925 120.3 1.3e-26 XP_016885220 (OMIM: 300573) PREDICTED: zinc finger ( 514) 925 120.3 1.3e-26 XP_016885217 (OMIM: 300573) PREDICTED: zinc finger ( 514) 925 120.3 1.3e-26 XP_016885218 (OMIM: 300573) PREDICTED: zinc finger ( 514) 925 120.3 1.3e-26 XP_011542246 (OMIM: 300573) PREDICTED: zinc finger ( 545) 925 120.3 1.4e-26 NP_001139763 (OMIM: 300573) zinc finger protein 67 ( 575) 925 120.3 1.4e-26 NP_001177346 (OMIM: 300573) zinc finger protein 67 ( 576) 925 120.3 1.4e-26 XP_011542245 (OMIM: 300573) PREDICTED: zinc finger ( 580) 925 120.3 1.4e-26 NP_001034980 (OMIM: 300573) zinc finger protein 67 ( 581) 925 120.3 1.4e-26 XP_011542243 (OMIM: 300573) PREDICTED: zinc finger ( 581) 925 120.3 1.4e-26 NP_001273627 (OMIM: 194552) zinc finger protein 79 ( 364) 921 119.6 1.5e-26 XP_006717342 (OMIM: 194552) PREDICTED: zinc finger ( 474) 921 119.7 1.7e-26 NP_001309189 (OMIM: 194552) zinc finger protein 79 ( 474) 921 119.7 1.7e-26 NP_001273625 (OMIM: 194552) zinc finger protein 79 ( 474) 921 119.7 1.7e-26 NP_001273626 (OMIM: 194552) zinc finger protein 79 ( 474) 921 119.7 1.7e-26 >>XP_005250625 (OMIM: 601261) PREDICTED: zinc finger and (473 aa) initn: 3321 init1: 3321 opt: 3321 Z-score: 2092.9 bits: 396.6 E(85289): 7.8e-110 Smith-Waterman score: 3321; 100.0% identity (100.0% similar) in 473 aa overlap (1-473:1-473) 10 20 30 40 50 60 pF1KB8 MMTKVLGMAPVLGPRPPQEQVGPLMVKVEEKEEKGKYLPSLEMFRQRFRQFGYHDTPGPR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MMTKVLGMAPVLGPRPPQEQVGPLMVKVEEKEEKGKYLPSLEMFRQRFRQFGYHDTPGPR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 EALSQLRVLCCEWLRPEIHTKEQILELLVLEQFLTILPQELQAWVQEHCPESAEEAVTLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EALSQLRVLCCEWLRPEIHTKEQILELLVLEQFLTILPQELQAWVQEHCPESAEEAVTLL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 EDLERELDEPGHQVSTPPNEQKPVWEKISSSGTAKESPSSMQPQPLETSHKYESWGPLYI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EDLERELDEPGHQVSTPPNEQKPVWEKISSSGTAKESPSSMQPQPLETSHKYESWGPLYI 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 QESGEEQEFAQDPRKVRDCRLSTQHEESADEQKGSEAEGLKGDIISVIIANKPEASLERQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 QESGEEQEFAQDPRKVRDCRLSTQHEESADEQKGSEAEGLKGDIISVIIANKPEASLERQ 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 CVNLENEKGTKPPLQEAGSKKGRESVPTKPTPGERRYICAECGKAFSNSSNLTKHRRTHT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 CVNLENEKGTKPPLQEAGSKKGRESVPTKPTPGERRYICAECGKAFSNSSNLTKHRRTHT 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 GEKPYVCTKCGKAFSHSSNLTLHYRTHLVDRPYDCKCGKAFGQSSDLLKHQRMHTEEAPY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GEKPYVCTKCGKAFSHSSNLTLHYRTHLVDRPYDCKCGKAFGQSSDLLKHQRMHTEEAPY 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB8 QCKDCGKAFSGKGSLIRHYRIHTGEKPYQCNECGKSFSQHAGLSSHQRLHTGEKPYKCKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 QCKDCGKAFSGKGSLIRHYRIHTGEKPYQCNECGKSFSQHAGLSSHQRLHTGEKPYKCKE 370 380 390 400 410 420 430 440 450 460 470 pF1KB8 CGKAFNHSSNFNKHHRIHTGEKPYWCHHCGKTFCSKSNLSKHQRVHTGEGEAP ::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 CGKAFNHSSNFNKHHRIHTGEKPYWCHHCGKTFCSKSNLSKHQRVHTGEGEAP 430 440 450 460 470 >>NP_666019 (OMIM: 601261) zinc finger and SCAN domain-c (473 aa) initn: 3321 init1: 3321 opt: 3321 Z-score: 2092.9 bits: 396.6 E(85289): 7.8e-110 Smith-Waterman score: 3321; 100.0% identity (100.0% similar) in 473 aa overlap (1-473:1-473) 10 20 30 40 50 60 pF1KB8 MMTKVLGMAPVLGPRPPQEQVGPLMVKVEEKEEKGKYLPSLEMFRQRFRQFGYHDTPGPR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_666 MMTKVLGMAPVLGPRPPQEQVGPLMVKVEEKEEKGKYLPSLEMFRQRFRQFGYHDTPGPR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 EALSQLRVLCCEWLRPEIHTKEQILELLVLEQFLTILPQELQAWVQEHCPESAEEAVTLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_666 EALSQLRVLCCEWLRPEIHTKEQILELLVLEQFLTILPQELQAWVQEHCPESAEEAVTLL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 EDLERELDEPGHQVSTPPNEQKPVWEKISSSGTAKESPSSMQPQPLETSHKYESWGPLYI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_666 EDLERELDEPGHQVSTPPNEQKPVWEKISSSGTAKESPSSMQPQPLETSHKYESWGPLYI 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 QESGEEQEFAQDPRKVRDCRLSTQHEESADEQKGSEAEGLKGDIISVIIANKPEASLERQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_666 QESGEEQEFAQDPRKVRDCRLSTQHEESADEQKGSEAEGLKGDIISVIIANKPEASLERQ 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 CVNLENEKGTKPPLQEAGSKKGRESVPTKPTPGERRYICAECGKAFSNSSNLTKHRRTHT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_666 CVNLENEKGTKPPLQEAGSKKGRESVPTKPTPGERRYICAECGKAFSNSSNLTKHRRTHT 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 GEKPYVCTKCGKAFSHSSNLTLHYRTHLVDRPYDCKCGKAFGQSSDLLKHQRMHTEEAPY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_666 GEKPYVCTKCGKAFSHSSNLTLHYRTHLVDRPYDCKCGKAFGQSSDLLKHQRMHTEEAPY 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB8 QCKDCGKAFSGKGSLIRHYRIHTGEKPYQCNECGKSFSQHAGLSSHQRLHTGEKPYKCKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_666 QCKDCGKAFSGKGSLIRHYRIHTGEKPYQCNECGKSFSQHAGLSSHQRLHTGEKPYKCKE 370 380 390 400 410 420 430 440 450 460 470 pF1KB8 CGKAFNHSSNFNKHHRIHTGEKPYWCHHCGKTFCSKSNLSKHQRVHTGEGEAP ::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_666 CGKAFNHSSNFNKHHRIHTGEKPYWCHHCGKTFCSKSNLSKHQRVHTGEGEAP 430 440 450 460 470 >>XP_006716176 (OMIM: 601261) PREDICTED: zinc finger and (473 aa) initn: 3321 init1: 3321 opt: 3321 Z-score: 2092.9 bits: 396.6 E(85289): 7.8e-110 Smith-Waterman score: 3321; 100.0% identity (100.0% similar) in 473 aa overlap (1-473:1-473) 10 20 30 40 50 60 pF1KB8 MMTKVLGMAPVLGPRPPQEQVGPLMVKVEEKEEKGKYLPSLEMFRQRFRQFGYHDTPGPR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 MMTKVLGMAPVLGPRPPQEQVGPLMVKVEEKEEKGKYLPSLEMFRQRFRQFGYHDTPGPR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 EALSQLRVLCCEWLRPEIHTKEQILELLVLEQFLTILPQELQAWVQEHCPESAEEAVTLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 EALSQLRVLCCEWLRPEIHTKEQILELLVLEQFLTILPQELQAWVQEHCPESAEEAVTLL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 EDLERELDEPGHQVSTPPNEQKPVWEKISSSGTAKESPSSMQPQPLETSHKYESWGPLYI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 EDLERELDEPGHQVSTPPNEQKPVWEKISSSGTAKESPSSMQPQPLETSHKYESWGPLYI 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 QESGEEQEFAQDPRKVRDCRLSTQHEESADEQKGSEAEGLKGDIISVIIANKPEASLERQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 QESGEEQEFAQDPRKVRDCRLSTQHEESADEQKGSEAEGLKGDIISVIIANKPEASLERQ 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 CVNLENEKGTKPPLQEAGSKKGRESVPTKPTPGERRYICAECGKAFSNSSNLTKHRRTHT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 CVNLENEKGTKPPLQEAGSKKGRESVPTKPTPGERRYICAECGKAFSNSSNLTKHRRTHT 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 GEKPYVCTKCGKAFSHSSNLTLHYRTHLVDRPYDCKCGKAFGQSSDLLKHQRMHTEEAPY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 GEKPYVCTKCGKAFSHSSNLTLHYRTHLVDRPYDCKCGKAFGQSSDLLKHQRMHTEEAPY 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB8 QCKDCGKAFSGKGSLIRHYRIHTGEKPYQCNECGKSFSQHAGLSSHQRLHTGEKPYKCKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 QCKDCGKAFSGKGSLIRHYRIHTGEKPYQCNECGKSFSQHAGLSSHQRLHTGEKPYKCKE 370 380 390 400 410 420 430 440 450 460 470 pF1KB8 CGKAFNHSSNFNKHHRIHTGEKPYWCHHCGKTFCSKSNLSKHQRVHTGEGEAP ::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 CGKAFNHSSNFNKHHRIHTGEKPYWCHHCGKTFCSKSNLSKHQRVHTGEGEAP 430 440 450 460 470 >>XP_016868073 (OMIM: 601261) PREDICTED: zinc finger and (473 aa) initn: 3321 init1: 3321 opt: 3321 Z-score: 2092.9 bits: 396.6 E(85289): 7.8e-110 Smith-Waterman score: 3321; 100.0% identity (100.0% similar) in 473 aa overlap (1-473:1-473) 10 20 30 40 50 60 pF1KB8 MMTKVLGMAPVLGPRPPQEQVGPLMVKVEEKEEKGKYLPSLEMFRQRFRQFGYHDTPGPR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MMTKVLGMAPVLGPRPPQEQVGPLMVKVEEKEEKGKYLPSLEMFRQRFRQFGYHDTPGPR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 EALSQLRVLCCEWLRPEIHTKEQILELLVLEQFLTILPQELQAWVQEHCPESAEEAVTLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EALSQLRVLCCEWLRPEIHTKEQILELLVLEQFLTILPQELQAWVQEHCPESAEEAVTLL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 EDLERELDEPGHQVSTPPNEQKPVWEKISSSGTAKESPSSMQPQPLETSHKYESWGPLYI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EDLERELDEPGHQVSTPPNEQKPVWEKISSSGTAKESPSSMQPQPLETSHKYESWGPLYI 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 QESGEEQEFAQDPRKVRDCRLSTQHEESADEQKGSEAEGLKGDIISVIIANKPEASLERQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QESGEEQEFAQDPRKVRDCRLSTQHEESADEQKGSEAEGLKGDIISVIIANKPEASLERQ 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 CVNLENEKGTKPPLQEAGSKKGRESVPTKPTPGERRYICAECGKAFSNSSNLTKHRRTHT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 CVNLENEKGTKPPLQEAGSKKGRESVPTKPTPGERRYICAECGKAFSNSSNLTKHRRTHT 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 GEKPYVCTKCGKAFSHSSNLTLHYRTHLVDRPYDCKCGKAFGQSSDLLKHQRMHTEEAPY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GEKPYVCTKCGKAFSHSSNLTLHYRTHLVDRPYDCKCGKAFGQSSDLLKHQRMHTEEAPY 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB8 QCKDCGKAFSGKGSLIRHYRIHTGEKPYQCNECGKSFSQHAGLSSHQRLHTGEKPYKCKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QCKDCGKAFSGKGSLIRHYRIHTGEKPYQCNECGKSFSQHAGLSSHQRLHTGEKPYKCKE 370 380 390 400 410 420 430 440 450 460 470 pF1KB8 CGKAFNHSSNFNKHHRIHTGEKPYWCHHCGKTFCSKSNLSKHQRVHTGEGEAP ::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 CGKAFNHSSNFNKHHRIHTGEKPYWCHHCGKTFCSKSNLSKHQRVHTGEGEAP 430 440 450 460 470 >>XP_016868074 (OMIM: 601261) PREDICTED: zinc finger and (450 aa) initn: 1778 init1: 1778 opt: 1784 Z-score: 1134.9 bits: 219.3 E(85289): 1.8e-56 Smith-Waterman score: 1784; 89.3% identity (92.3% similar) in 300 aa overlap (1-300:1-293) 10 20 30 40 50 60 pF1KB8 MMTKVLGMAPVLGPRPPQEQVGPLMVKVEEKEEKGKYLPSLEMFRQRFRQFGYHDTPGPR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MMTKVLGMAPVLGPRPPQEQVGPLMVKVEEKEEKGKYLPSLEMFRQRFRQFGYHDTPGPR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 EALSQLRVLCCEWLRPEIHTKEQILELLVLEQFLTILPQELQAWVQEHCPESAEEAVTLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EALSQLRVLCCEWLRPEIHTKEQILELLVLEQFLTILPQELQAWVQEHCPESAEEAVTLL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 EDLERELDEPGHQVSTPPNEQKPVWEKISSSGTAKESPSSMQPQPLETSHKYESWGPLYI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EDLERELDEPGHQVSTPPNEQKPVWEKISSSGTAKESPSSMQPQPLETSHKYESWGPLYI 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 QESGEEQEFAQDPRKVRDCRLSTQHEESADEQKGSEAEGLKGDIISVIIANKPEASLERQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QESGEEQEFAQDPRKVRDCRLSTQHEESADEQKGSEAEGLKGDIISVIIANKPEASLERQ 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 CVNLENEKGTKPPLQEAGSKKGRESVPTKPTPGERRYICAECGKAFSNSSNLTKHRRTHT ::::::::::::::::::::::.... : :: .: ... . :: XP_016 CVNLENEKGTKPPLQEAGSKKGEHTLG-------RNLTCAPSVGKLSATAQTSPSTTEHT 250 260 270 280 290 310 320 330 340 350 360 pF1KB8 GEKPYVCTKCGKAFSHSSNLTLHYRTHLVDRPYDCKCGKAFGQSSDLLKHQRMHTEEAPY XP_016 WWTGPMTVSVEKLLGRAQTFLNIRECTQKRRHISAKIVARLSAGKAASFVTIGSTLGRSL 300 310 320 330 340 350 >>XP_016866753 (OMIM: 616474) PREDICTED: zinc finger and (478 aa) initn: 1611 init1: 704 opt: 1114 Z-score: 716.9 bits: 142.0 E(85289): 3.4e-33 Smith-Waterman score: 1137; 43.4% identity (67.6% similar) in 438 aa overlap (46-466:52-472) 20 30 40 50 60 70 pF1KB8 PPQEQVGPLMVKVEEKEEKGKYLPSLEMFRQRFRQFGYHDTPGPREALSQLRVLCCEWLR ..:::. :..: :::::::.:: :: .::. XP_016 RVVREDHYSTWEQGFKLQGNSKGLGQEPLCKQFRQLRYEETTGPREALSRLRELCQQWLQ 30 40 50 60 70 80 80 90 100 110 120 130 pF1KB8 PEIHTKEQILELLVLEQFLTILPQELQAWVQEHCPESAEEAVTLLEDLERELDEPGHQVS :: :::::::::::::::: :::.:::: :::: ::: :..:..::::. .: : :.: XP_016 PETHTKEQILELLVLEQFLIILPKELQARVQEHHPESREDVVVVLEDLQLDLGETGQQDP 90 100 110 120 130 140 140 150 160 170 180 190 pF1KB8 TPPNEQKPVWEKISSSGTAKESPSSMQPQPLETSHKYESWGPLYIQESGEEQEFAQDPRK :..:: . :... ...: : .. :. : : .:.::: .. . XP_016 DQPKKQKILVEEMAPL-------KGVQEQ--QVRHECEVTKPE--KEKGEETRIENGKLI 150 160 170 180 190 200 210 220 230 240 250 pF1KB8 V--RDC-RLSTQHEESADEQKGSEAEGLKGDIISVIIANKPEASLERQCVNLENEKGTKP : .: :. .. . : . .:. .:. ::. ..: .: . :.. . XP_016 VVTDSCGRVESSGKISEPMEAHNEGSNLERH------QAKPKEKIEYKCSEREQRFIQHL 200 210 220 230 240 260 270 280 290 pF1KB8 PLQE-AGSKKGR---ES--VPTKPTPGERRYI-------CAECGKAFSNSSNLTKHRRTH : : :... :. :: .. :... . : ::::::. ::.:..:.. : XP_016 DLIEHASTHTGKKLCESDVCQSSSLTGHKKVLSREKGHQCHECGKAFQRSSHLVRHQKIH 250 260 270 280 290 300 300 310 320 330 340 350 pF1KB8 TGEKPYVCTKCGKAFSHSSNLTLHYRTHLVDRPYDC-KCGKAFGQSSDLLKHQRMHTEEA ::::: :..:::.::....: : : : ..:: : .::: : .:: : .:::.:..: XP_016 LGEKPYQCNECGKVFSQNAGLLEHLRIHTGEKPYLCIHCGKNFRRSSHLNRHQRIHSQEE 310 320 330 340 350 360 360 370 380 390 400 410 pF1KB8 PYQCKDCGKAFSGKGSLIRHYRIHTGEKPYQCNECGKSFSQHAGLSSHQRLHTGEKPYKC : .::.:::.:: : .: :::. : .:::::::.:: . : :.:.::::::.:: XP_016 PCECKECGKTFSQALLLTHHQRIHSHSKSHQCNECGKAFSLTSDLIRHHRIHTGEKPFKC 370 380 390 400 410 420 420 430 440 450 460 470 pF1KB8 KECGKAFNHSSNFNKHHRIHTGEKPYWCHHCGKTFCSKSNLSKHQRVHTGEGEAP . : ::: .:.. .: :::. :::: : .::..: ..:.: .::: : XP_016 NICQKAFRLNSHLAQHVRIHNEEKPYQCSECGEAFRQRSGLFQHQRYHHKDKLA 430 440 450 460 470 >>NP_001104509 (OMIM: 616474) zinc finger and SCAN domai (478 aa) initn: 1611 init1: 704 opt: 1114 Z-score: 716.9 bits: 142.0 E(85289): 3.4e-33 Smith-Waterman score: 1137; 43.4% identity (67.6% similar) in 438 aa overlap (46-466:52-472) 20 30 40 50 60 70 pF1KB8 PPQEQVGPLMVKVEEKEEKGKYLPSLEMFRQRFRQFGYHDTPGPREALSQLRVLCCEWLR ..:::. :..: :::::::.:: :: .::. NP_001 RVVREDHYSTWEQGFKLQGNSKGLGQEPLCKQFRQLRYEETTGPREALSRLRELCQQWLQ 30 40 50 60 70 80 80 90 100 110 120 130 pF1KB8 PEIHTKEQILELLVLEQFLTILPQELQAWVQEHCPESAEEAVTLLEDLERELDEPGHQVS :: :::::::::::::::: :::.:::: :::: ::: :..:..::::. .: : :.: NP_001 PETHTKEQILELLVLEQFLIILPKELQARVQEHHPESREDVVVVLEDLQLDLGETGQQDP 90 100 110 120 130 140 140 150 160 170 180 190 pF1KB8 TPPNEQKPVWEKISSSGTAKESPSSMQPQPLETSHKYESWGPLYIQESGEEQEFAQDPRK :..:: . :... ...: : .. :. : : .:.::: .. . NP_001 DQPKKQKILVEEMAPL-------KGVQEQ--QVRHECEVTKPE--KEKGEETRIENGKLI 150 160 170 180 190 200 210 220 230 240 250 pF1KB8 V--RDC-RLSTQHEESADEQKGSEAEGLKGDIISVIIANKPEASLERQCVNLENEKGTKP : .: :. .. . : . .:. .:. ::. ..: .: . :.. . NP_001 VVTDSCGRVESSGKISEPMEAHNEGSNLERH------QAKPKEKIEYKCSEREQRFIQHL 200 210 220 230 240 260 270 280 290 pF1KB8 PLQE-AGSKKGR---ES--VPTKPTPGERRYI-------CAECGKAFSNSSNLTKHRRTH : : :... :. :: .. :... . : ::::::. ::.:..:.. : NP_001 DLIEHASTHTGKKLCESDVCQSSSLTGHKKVLSREKGHQCHECGKAFQRSSHLVRHQKIH 250 260 270 280 290 300 300 310 320 330 340 350 pF1KB8 TGEKPYVCTKCGKAFSHSSNLTLHYRTHLVDRPYDC-KCGKAFGQSSDLLKHQRMHTEEA ::::: :..:::.::....: : : : ..:: : .::: : .:: : .:::.:..: NP_001 LGEKPYQCNECGKVFSQNAGLLEHLRIHTGEKPYLCIHCGKNFRRSSHLNRHQRIHSQEE 310 320 330 340 350 360 360 370 380 390 400 410 pF1KB8 PYQCKDCGKAFSGKGSLIRHYRIHTGEKPYQCNECGKSFSQHAGLSSHQRLHTGEKPYKC : .::.:::.:: : .: :::. : .:::::::.:: . : :.:.::::::.:: NP_001 PCECKECGKTFSQALLLTHHQRIHSHSKSHQCNECGKAFSLTSDLIRHHRIHTGEKPFKC 370 380 390 400 410 420 420 430 440 450 460 470 pF1KB8 KECGKAFNHSSNFNKHHRIHTGEKPYWCHHCGKTFCSKSNLSKHQRVHTGEGEAP . : ::: .:.. .: :::. :::: : .::..: ..:.: .::: : NP_001 NICQKAFRLNSHLAQHVRIHNEEKPYQCSECGEAFRQRSGLFQHQRYHHKDKLA 430 440 450 460 470 >>XP_016866748 (OMIM: 600834) PREDICTED: zinc finger pro (485 aa) initn: 1812 init1: 587 opt: 1110 Z-score: 714.3 bits: 141.6 E(85289): 4.8e-33 Smith-Waterman score: 1169; 42.1% identity (68.0% similar) in 478 aa overlap (17-469:14-481) 10 20 30 40 50 pF1KB8 MMTKVLGMAPVLGPRPPQEQVGPLMVKVEEKE---------EKGKYLPSLEMFRQRFRQF :... : :.::.::.: .... : . :. :: :::: XP_016 MATEPKKAAAQNSPEDE-GLLIVKIEEEEFIHGQDTCLQRSELLKQ-ELCRQLFRQF 10 20 30 40 50 60 70 80 90 100 110 pF1KB8 GYHDTPGPREALSQLRVLCCEWLRPEIHTKEQILELLVLEQFLTILPQELQAWVQEHCPE :.:.::::::::.:: :::.::.::::::::::::::::::::::: .:::::.:: :: XP_016 CYQDSPGPREALSRLRELCCQWLKPEIHTKEQILELLVLEQFLTILPGDLQAWVHEHYPE 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB8 SAEEAVTLLEDLERELDEPGHQVSTPPNEQKPVWEKISSSGTAKESPSSMQPQPLETSHK :.:::::.:::::: :: ::.. . :. .:.: : : ... ::.::. . XP_016 SGEEAVTILEDLERGTDEAVLQVQAHEHGQEIFQKKVSPPGPAL----NVKLQPVETKAH 120 130 140 150 160 170 180 190 200 210 220 pF1KB8 YESWGPLYIQESGEEQEFAQDPRKVRDCRLSTQHEESADEQKG--SEAEGLKGDIISVII ..: : . . .:.: ... :.. . ... . . .: ::: : . :: . XP_016 FDSSEPQLLWDCDNESENSRSMPKLEIFEKIESQRIISGRISGYISEASGESQDICKSAG 180 190 200 210 220 230 230 240 250 260 270 pF1KB8 ANK---PEASLERQCVNLENEKGTKPPLQEAGSKKG----------RESVPTKPTPGERR : . : : : .. ...: : . .. .: : .. .. .. XP_016 RVKRQWEKESGESQRLSSAQDEGFGKILTHKNTVRGEIISHDGCERRLNLNSNEFTHQKS 240 250 260 270 280 290 280 290 300 310 320 330 pF1KB8 YICAECGKAFSNSSNLTKHRRTHTGEKPYVCTKCGKAFSHSSNLTLHYRTHLVDRPYDC- . : ..:. .:.. .:. ..::: . . ::.:. : .:. : . :. ..: XP_016 CKHGTCDQSFKWNSDFINHQIIYAGEKNH---QYGKSFK-SPKLAKHAAVFSGDKTHQCN 300 310 320 330 340 340 350 360 370 380 390 pF1KB8 KCGKAFGQSSDLLKHQRMHTEEAPYQCKDCGKAFSGKGSLIRHYRIHTGEKPYQCNECGK .::::: .:: : .:::.:: : :.:..:::.:. ...: :: ::::::.:. :.:::. XP_016 ECGKAFRHSSKLARHQRIHTGERCYECNECGKSFAESSDLTRHRRIHTGERPFGCKECGR 350 360 370 380 390 400 400 410 420 430 440 450 pF1KB8 SFSQHAGLSSHQRLHTGEKPYKCKECGKAFNHSSNFNKHHRIHTGEKPYWCHHCGKTFCS .:. .. : :::.:: ::::.:.::::.: ::.. .: ::::::::: : .::..: . XP_016 AFNLNSHLIRHQRIHTREKPYECSECGKTFRVSSHLIRHFRIHTGEKPYECSECGRAFSQ 410 420 430 440 450 460 460 470 pF1KB8 KSNLSKHQRVHTGEGEAP .::::.:::.: : XP_016 SSNLSQHQRIHMRENLLM 470 480 >>XP_016866747 (OMIM: 600834) PREDICTED: zinc finger pro (485 aa) initn: 1812 init1: 587 opt: 1110 Z-score: 714.3 bits: 141.6 E(85289): 4.8e-33 Smith-Waterman score: 1169; 42.1% identity (68.0% similar) in 478 aa overlap (17-469:14-481) 10 20 30 40 50 pF1KB8 MMTKVLGMAPVLGPRPPQEQVGPLMVKVEEKE---------EKGKYLPSLEMFRQRFRQF :... : :.::.::.: .... : . :. :: :::: XP_016 MATEPKKAAAQNSPEDE-GLLIVKIEEEEFIHGQDTCLQRSELLKQ-ELCRQLFRQF 10 20 30 40 50 60 70 80 90 100 110 pF1KB8 GYHDTPGPREALSQLRVLCCEWLRPEIHTKEQILELLVLEQFLTILPQELQAWVQEHCPE :.:.::::::::.:: :::.::.::::::::::::::::::::::: .:::::.:: :: XP_016 CYQDSPGPREALSRLRELCCQWLKPEIHTKEQILELLVLEQFLTILPGDLQAWVHEHYPE 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB8 SAEEAVTLLEDLERELDEPGHQVSTPPNEQKPVWEKISSSGTAKESPSSMQPQPLETSHK :.:::::.:::::: :: ::.. . :. .:.: : : ... ::.::. . XP_016 SGEEAVTILEDLERGTDEAVLQVQAHEHGQEIFQKKVSPPGPAL----NVKLQPVETKAH 120 130 140 150 160 170 180 190 200 210 220 pF1KB8 YESWGPLYIQESGEEQEFAQDPRKVRDCRLSTQHEESADEQKG--SEAEGLKGDIISVII ..: : . . .:.: ... :.. . ... . . .: ::: : . :: . XP_016 FDSSEPQLLWDCDNESENSRSMPKLEIFEKIESQRIISGRISGYISEASGESQDICKSAG 180 190 200 210 220 230 230 240 250 260 270 pF1KB8 ANK---PEASLERQCVNLENEKGTKPPLQEAGSKKG----------RESVPTKPTPGERR : . : : : .. ...: : . .. .: : .. .. .. XP_016 RVKRQWEKESGESQRLSSAQDEGFGKILTHKNTVRGEIISHDGCERRLNLNSNEFTHQKS 240 250 260 270 280 290 280 290 300 310 320 330 pF1KB8 YICAECGKAFSNSSNLTKHRRTHTGEKPYVCTKCGKAFSHSSNLTLHYRTHLVDRPYDC- . : ..:. .:.. .:. ..::: . . ::.:. : .:. : . :. ..: XP_016 CKHGTCDQSFKWNSDFINHQIIYAGEKNH---QYGKSFK-SPKLAKHAAVFSGDKTHQCN 300 310 320 330 340 340 350 360 370 380 390 pF1KB8 KCGKAFGQSSDLLKHQRMHTEEAPYQCKDCGKAFSGKGSLIRHYRIHTGEKPYQCNECGK .::::: .:: : .:::.:: : :.:..:::.:. ...: :: ::::::.:. :.:::. XP_016 ECGKAFRHSSKLARHQRIHTGERCYECNECGKSFAESSDLTRHRRIHTGERPFGCKECGR 350 360 370 380 390 400 400 410 420 430 440 450 pF1KB8 SFSQHAGLSSHQRLHTGEKPYKCKECGKAFNHSSNFNKHHRIHTGEKPYWCHHCGKTFCS .:. .. : :::.:: ::::.:.::::.: ::.. .: ::::::::: : .::..: . XP_016 AFNLNSHLIRHQRIHTREKPYECSECGKTFRVSSHLIRHFRIHTGEKPYECSECGRAFSQ 410 420 430 440 450 460 460 470 pF1KB8 KSNLSKHQRVHTGEGEAP .::::.:::.: : XP_016 SSNLSQHQRIHMRENLLM 470 480 >>XP_016866749 (OMIM: 600834) PREDICTED: zinc finger pro (485 aa) initn: 1812 init1: 587 opt: 1110 Z-score: 714.3 bits: 141.6 E(85289): 4.8e-33 Smith-Waterman score: 1169; 42.1% identity (68.0% similar) in 478 aa overlap (17-469:14-481) 10 20 30 40 50 pF1KB8 MMTKVLGMAPVLGPRPPQEQVGPLMVKVEEKE---------EKGKYLPSLEMFRQRFRQF :... : :.::.::.: .... : . :. :: :::: XP_016 MATEPKKAAAQNSPEDE-GLLIVKIEEEEFIHGQDTCLQRSELLKQ-ELCRQLFRQF 10 20 30 40 50 60 70 80 90 100 110 pF1KB8 GYHDTPGPREALSQLRVLCCEWLRPEIHTKEQILELLVLEQFLTILPQELQAWVQEHCPE :.:.::::::::.:: :::.::.::::::::::::::::::::::: .:::::.:: :: XP_016 CYQDSPGPREALSRLRELCCQWLKPEIHTKEQILELLVLEQFLTILPGDLQAWVHEHYPE 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB8 SAEEAVTLLEDLERELDEPGHQVSTPPNEQKPVWEKISSSGTAKESPSSMQPQPLETSHK :.:::::.:::::: :: ::.. . :. .:.: : : ... ::.::. . XP_016 SGEEAVTILEDLERGTDEAVLQVQAHEHGQEIFQKKVSPPGPAL----NVKLQPVETKAH 120 130 140 150 160 170 180 190 200 210 220 pF1KB8 YESWGPLYIQESGEEQEFAQDPRKVRDCRLSTQHEESADEQKG--SEAEGLKGDIISVII ..: : . . .:.: ... :.. . ... . . .: ::: : . :: . XP_016 FDSSEPQLLWDCDNESENSRSMPKLEIFEKIESQRIISGRISGYISEASGESQDICKSAG 180 190 200 210 220 230 230 240 250 260 270 pF1KB8 ANK---PEASLERQCVNLENEKGTKPPLQEAGSKKG----------RESVPTKPTPGERR : . : : : .. ...: : . .. .: : .. .. .. XP_016 RVKRQWEKESGESQRLSSAQDEGFGKILTHKNTVRGEIISHDGCERRLNLNSNEFTHQKS 240 250 260 270 280 290 280 290 300 310 320 330 pF1KB8 YICAECGKAFSNSSNLTKHRRTHTGEKPYVCTKCGKAFSHSSNLTLHYRTHLVDRPYDC- . : ..:. .:.. .:. ..::: . . ::.:. : .:. : . :. ..: XP_016 CKHGTCDQSFKWNSDFINHQIIYAGEKNH---QYGKSFK-SPKLAKHAAVFSGDKTHQCN 300 310 320 330 340 340 350 360 370 380 390 pF1KB8 KCGKAFGQSSDLLKHQRMHTEEAPYQCKDCGKAFSGKGSLIRHYRIHTGEKPYQCNECGK .::::: .:: : .:::.:: : :.:..:::.:. ...: :: ::::::.:. :.:::. XP_016 ECGKAFRHSSKLARHQRIHTGERCYECNECGKSFAESSDLTRHRRIHTGERPFGCKECGR 350 360 370 380 390 400 400 410 420 430 440 450 pF1KB8 SFSQHAGLSSHQRLHTGEKPYKCKECGKAFNHSSNFNKHHRIHTGEKPYWCHHCGKTFCS .:. .. : :::.:: ::::.:.::::.: ::.. .: ::::::::: : .::..: . XP_016 AFNLNSHLIRHQRIHTREKPYECSECGKTFRVSSHLIRHFRIHTGEKPYECSECGRAFSQ 410 420 430 440 450 460 460 470 pF1KB8 KSNLSKHQRVHTGEGEAP .::::.:::.: : XP_016 SSNLSQHQRIHMRENLLM 470 480 473 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 11:28:58 2016 done: Fri Nov 4 11:28:59 2016 Total Scan time: 5.980 Total Display time: 0.060 Function used was FASTA [36.3.4 Apr, 2011]