FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB8297, 191 aa 1>>>pF1KB8297 191 - 191 aa - 191 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.0295+/-0.000991; mu= 15.1542+/- 0.060 mean_var=84.4013+/-16.462, 0's: 0 Z-trim(106.3): 91 B-trim: 4 in 1/49 Lambda= 0.139605 statistics sampled from 8786 (8891) to 8786 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.655), E-opt: 0.2 (0.273), width: 16 Scan time: 1.850 The best scores are: opt bits E(32554) CCDS441.1 HPCAL4 gene_id:51440|Hs108|chr1 ( 191) 1275 266.3 8.2e-72 CCDS1689.1 VSNL1 gene_id:7447|Hs108|chr2 ( 191) 1181 247.3 4.1e-66 CCDS1671.1 HPCAL1 gene_id:3241|Hs108|chr2 ( 193) 899 190.6 5.2e-49 CCDS370.1 HPCA gene_id:3208|Hs108|chr1 ( 193) 898 190.4 6e-49 CCDS6292.1 NCALD gene_id:83988|Hs108|chr8 ( 193) 890 188.7 1.8e-48 CCDS6932.1 NCS1 gene_id:23413|Hs108|chr9 ( 190) 746 159.7 9.7e-40 CCDS78448.1 NCS1 gene_id:23413|Hs108|chr9 ( 172) 654 141.2 3.4e-34 CCDS11151.1 RCVRN gene_id:5957|Hs108|chr17 ( 200) 609 132.2 2e-31 CCDS64313.1 KCNIP1 gene_id:30820|Hs108|chr5 ( 188) 555 121.3 3.7e-28 CCDS4374.1 KCNIP1 gene_id:30820|Hs108|chr5 ( 216) 555 121.3 4e-28 CCDS7524.1 KCNIP2 gene_id:30819|Hs108|chr10 ( 220) 555 121.3 4.1e-28 CCDS7525.1 KCNIP2 gene_id:30819|Hs108|chr10 ( 225) 555 121.3 4.2e-28 CCDS34285.1 KCNIP1 gene_id:30820|Hs108|chr5 ( 225) 555 121.3 4.2e-28 CCDS34286.1 KCNIP1 gene_id:30820|Hs108|chr5 ( 227) 555 121.3 4.2e-28 CCDS41562.1 KCNIP2 gene_id:30819|Hs108|chr10 ( 252) 555 121.4 4.5e-28 CCDS7522.1 KCNIP2 gene_id:30819|Hs108|chr10 ( 270) 555 121.4 4.7e-28 CCDS7521.1 KCNIP2 gene_id:30819|Hs108|chr10 ( 285) 555 121.4 4.9e-28 CCDS47035.1 KCNIP4 gene_id:80333|Hs108|chr4 ( 188) 543 118.8 2e-27 CCDS43215.1 KCNIP4 gene_id:80333|Hs108|chr4 ( 216) 543 118.9 2.2e-27 CCDS43217.1 KCNIP4 gene_id:80333|Hs108|chr4 ( 225) 543 118.9 2.2e-27 CCDS3428.1 KCNIP4 gene_id:80333|Hs108|chr4 ( 229) 543 118.9 2.3e-27 CCDS43216.1 KCNIP4 gene_id:80333|Hs108|chr4 ( 250) 543 119.0 2.4e-27 CCDS7523.1 KCNIP2 gene_id:30819|Hs108|chr10 ( 227) 537 117.7 5.2e-27 CCDS33245.1 KCNIP3 gene_id:30818|Hs108|chr2 ( 230) 522 114.7 4.2e-26 CCDS2013.1 KCNIP3 gene_id:30818|Hs108|chr2 ( 256) 522 114.7 4.6e-26 CCDS4865.1 GUCA1B gene_id:2979|Hs108|chr6 ( 200) 494 109.0 1.9e-24 CCDS72761.1 HPCAL4 gene_id:51440|Hs108|chr1 ( 119) 446 99.1 1.1e-21 CCDS4864.1 GUCA1A gene_id:2978|Hs108|chr6 ( 201) 413 92.7 1.6e-19 CCDS64312.1 KCNIP1 gene_id:30820|Hs108|chr5 ( 241) 381 86.3 1.5e-17 CCDS2954.1 GUCA1C gene_id:9626|Hs108|chr3 ( 209) 350 80.0 1.1e-15 CCDS7526.1 KCNIP2 gene_id:30819|Hs108|chr10 ( 184) 273 64.5 4.5e-11 >>CCDS441.1 HPCAL4 gene_id:51440|Hs108|chr1 (191 aa) initn: 1275 init1: 1275 opt: 1275 Z-score: 1402.7 bits: 266.3 E(32554): 8.2e-72 Smith-Waterman score: 1275; 100.0% identity (100.0% similar) in 191 aa overlap (1-191:1-191) 10 20 30 40 50 60 pF1KB8 MGKTNSKLAPEVLEDLVQNTEFSEQELKQWYKGFLKDCPSGILNLEEFQQLYIKFFPYGD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 MGKTNSKLAPEVLEDLVQNTEFSEQELKQWYKGFLKDCPSGILNLEEFQQLYIKFFPYGD 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 ASKFAQHAFRTFDKNGDGTIDFREFICALSVTSRGSFEQKLNWAFEMYDLDGDGRITRLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 ASKFAQHAFRTFDKNGDGTIDFREFICALSVTSRGSFEQKLNWAFEMYDLDGDGRITRLE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 MLEIIEAIYKMVGTVIMMRMNQDGLTPQQRVDKIFKKMDQDKDDQITLEEFKEAAKSDPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 MLEIIEAIYKMVGTVIMMRMNQDGLTPQQRVDKIFKKMDQDKDDQITLEEFKEAAKSDPS 130 140 150 160 170 180 190 pF1KB8 IVLLLQCDMQK ::::::::::: CCDS44 IVLLLQCDMQK 190 >>CCDS1689.1 VSNL1 gene_id:7447|Hs108|chr2 (191 aa) initn: 1181 init1: 1181 opt: 1181 Z-score: 1300.4 bits: 247.3 E(32554): 4.1e-66 Smith-Waterman score: 1181; 89.5% identity (99.0% similar) in 191 aa overlap (1-191:1-191) 10 20 30 40 50 60 pF1KB8 MGKTNSKLAPEVLEDLVQNTEFSEQELKQWYKGFLKDCPSGILNLEEFQQLYIKFFPYGD ::: ::::::::.::::..:::.:.:::::::::::::::: ::::::::::.::::::: CCDS16 MGKQNSKLAPEVMEDLVKSTEFNEHELKQWYKGFLKDCPSGRLNLEEFQQLYVKFFPYGD 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 ASKFAQHAFRTFDKNGDGTIDFREFICALSVTSRGSFEQKLNWAFEMYDLDGDGRITRLE ::::::::::::::::::::::::::::::.::::::::::::::.::::::::.:::.: CCDS16 ASKFAQHAFRTFDKNGDGTIDFREFICALSITSRGSFEQKLNWAFNMYDLDGDGKITRVE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 MLEIIEAIYKMVGTVIMMRMNQDGLTPQQRVDKIFKKMDQDKDDQITLEEFKEAAKSDPS ::::::::::::::::::.::.:::::.:::::::.:::..:::::::.::::::::::: CCDS16 MLEIIEAIYKMVGTVIMMKMNEDGLTPEQRVDKIFSKMDKNKDDQITLDEFKEAAKSDPS 130 140 150 160 170 180 190 pF1KB8 IVLLLQCDMQK ::::::::.:: CCDS16 IVLLLQCDIQK 190 >>CCDS1671.1 HPCAL1 gene_id:3241|Hs108|chr2 (193 aa) initn: 722 init1: 708 opt: 899 Z-score: 993.4 bits: 190.6 E(32554): 5.2e-49 Smith-Waterman score: 899; 68.6% identity (89.9% similar) in 188 aa overlap (1-188:1-186) 10 20 30 40 50 60 pF1KB8 MGKTNSKLAPEVLEDLVQNTEFSEQELKQWYKGFLKDCPSGILNLEEFQQLYIKFFPYGD ::: :::: ::::.:: .::::...::..::::::::::.: :...::...: .:::::: CCDS16 MGKQNSKLRPEVLQDLRENTEFTDHELQEWYKGFLKDCPTGHLTVDEFKKIYANFFPYGD 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 ASKFAQHAFRTFDKNGDGTIDFREFICALSVTSRGSFEQKLNWAFEMYDLDGDGRITRLE :::::.:.::::: :::::::::::: ::::::::..::::.::: ::::::.: :.: : CCDS16 ASKFAEHVFRTFDTNGDGTIDFREFIIALSVTSRGKLEQKLKWAFSMYDLDGNGYISRSE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 MLEIIEAIYKMVGTVIMMRMNQDGLTPQQRVDKIFKKMDQDKDDQITLEEFKEAAKSDPS ::::..::::::..: :.: .: ::..:.::::..:: ..: ...:::: ..:::::: CCDS16 MLEIVQAIYKMVSSV--MKMPEDESTPEKRTDKIFRQMDTNNDGKLSLEEFIRGAKSDPS 130 140 150 160 170 190 pF1KB8 IVLLLQCDMQK :: ::::: CCDS16 IVRLLQCDPSSASQF 180 190 >>CCDS370.1 HPCA gene_id:3208|Hs108|chr1 (193 aa) initn: 729 init1: 713 opt: 898 Z-score: 992.3 bits: 190.4 E(32554): 6e-49 Smith-Waterman score: 898; 69.1% identity (88.8% similar) in 188 aa overlap (1-188:1-186) 10 20 30 40 50 60 pF1KB8 MGKTNSKLAPEVLEDLVQNTEFSEQELKQWYKGFLKDCPSGILNLEEFQQLYIKFFPYGD ::: :::: ::.:.:: .:::::: ::..::::::::::.::::..::...: .:::::: CCDS37 MGKQNSKLRPEMLQDLRENTEFSELELQEWYKGFLKDCPTGILNVDEFKKIYANFFPYGD 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 ASKFAQHAFRTFDKNGDGTIDFREFICALSVTSRGSFEQKLNWAFEMYDLDGDGRITRLE :::::.:.::::: :.:::::::::: :::::::: .:::: ::: ::::::.: :.: : CCDS37 ASKFAEHVFRTFDTNSDGTIDFREFIIALSVTSRGRLEQKLMWAFSMYDLDGNGYISREE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 MLEIIEAIYKMVGTVIMMRMNQDGLTPQQRVDKIFKKMDQDKDDQITLEEFKEAAKSDPS ::::..::::::..: :.: .: ::..:..:::..:: ..: ...:::: ..:::::: CCDS37 MLEIVQAIYKMVSSV--MKMPEDESTPEKRTEKIFRQMDTNNDGKLSLEEFIRGAKSDPS 130 140 150 160 170 190 pF1KB8 IVLLLQCDMQK :: ::::: CCDS37 IVRLLQCDPSSASQF 180 190 >>CCDS6292.1 NCALD gene_id:83988|Hs108|chr8 (193 aa) initn: 716 init1: 702 opt: 890 Z-score: 983.6 bits: 188.7 E(32554): 1.8e-48 Smith-Waterman score: 890; 66.5% identity (90.4% similar) in 188 aa overlap (1-188:1-186) 10 20 30 40 50 60 pF1KB8 MGKTNSKLAPEVLEDLVQNTEFSEQELKQWYKGFLKDCPSGILNLEEFQQLYIKFFPYGD ::: :::: :::..::...:.:.:.:...::::::.::::: :..:::...: .:::::: CCDS62 MGKQNSKLRPEVMQDLLESTDFTEHEIQEWYKGFLRDCPSGHLSMEEFKKIYGNFFPYGD 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 ASKFAQHAFRTFDKNGDGTIDFREFICALSVTSRGSFEQKLNWAFEMYDLDGDGRITRLE :::::.:.::::: :::::::::::: ::::::::..::::.::: ::::::.: :.. : CCDS62 ASKFAEHVFRTFDANGDGTIDFREFIIALSVTSRGKLEQKLKWAFSMYDLDGNGYISKAE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 MLEIIEAIYKMVGTVIMMRMNQDGLTPQQRVDKIFKKMDQDKDDQITLEEFKEAAKSDPS ::::..::::::..: :.: .: ::..:..:::..:: ..: ...:::: ..:::::: CCDS62 MLEIVQAIYKMVSSV--MKMPEDESTPEKRTEKIFRQMDTNRDGKLSLEEFIRGAKSDPS 130 140 150 160 170 190 pF1KB8 IVLLLQCDMQK :: ::::: CCDS62 IVRLLQCDPSSAGQF 180 190 >>CCDS6932.1 NCS1 gene_id:23413|Hs108|chr9 (190 aa) initn: 799 init1: 604 opt: 746 Z-score: 826.9 bits: 159.7 E(32554): 9.7e-40 Smith-Waterman score: 746; 56.8% identity (84.3% similar) in 185 aa overlap (1-185:1-183) 10 20 30 40 50 60 pF1KB8 MGKTNSKLAPEVLEDLVQNTEFSEQELKQWYKGFLKDCPSGILNLEEFQQLYIKFFPYGD :::.:::: :::.:.:...: :.:.:..::::::.:::::: :. ::..: .:::.:: CCDS69 MGKSNSKLKPEVVEELTRKTYFTEKEVQQWYKGFIKDCPSGQLDAAGFQKIYKQFFPFGD 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 ASKFAQHAFRTFDKNGDGTIDFREFICALSVTSRGSFEQKLNWAFEMYDLDGDGRITRLE .::: .: .::.: :: :.: ::: ::::::::....:: :::..::::.:: ::: : CCDS69 PTKFATFVFNVFDENKDGRIEFSEFIQALSVTSRGTLDEKLRWAFKLYDLDNDGYITRNE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 MLEIIEAIYKMVGTVIMMRMNQDGLTPQQRVDKIFKKMDQDKDDQITLEEFKEAAKSDPS ::.:..:::.:::... . ... ::..:::.:: ::.. : ..::.::.:..:.::: CCDS69 MLDIVDAIYQMVGNTVELPEEEN--TPEKRVDRIFAMMDKNADGKLTLQEFQEGSKADPS 130 140 150 160 170 190 pF1KB8 IVLLLQCDMQK :: : CCDS69 IVQALSLYDGLV 180 190 >>CCDS78448.1 NCS1 gene_id:23413|Hs108|chr9 (172 aa) initn: 688 init1: 493 opt: 654 Z-score: 727.3 bits: 141.2 E(32554): 3.4e-34 Smith-Waterman score: 654; 55.8% identity (83.4% similar) in 163 aa overlap (23-185:5-165) 10 20 30 40 50 60 pF1KB8 MGKTNSKLAPEVLEDLVQNTEFSEQELKQWYKGFLKDCPSGILNLEEFQQLYIKFFPYGD .:.:..::::::.:::::: :. ::..: .:::.:: CCDS78 MATITEKEVQQWYKGFIKDCPSGQLDAAGFQKIYKQFFPFGD 10 20 30 40 70 80 90 100 110 120 pF1KB8 ASKFAQHAFRTFDKNGDGTIDFREFICALSVTSRGSFEQKLNWAFEMYDLDGDGRITRLE .::: .: .::.: :: :.: ::: ::::::::....:: :::..::::.:: ::: : CCDS78 PTKFATFVFNVFDENKDGRIEFSEFIQALSVTSRGTLDEKLRWAFKLYDLDNDGYITRNE 50 60 70 80 90 100 130 140 150 160 170 180 pF1KB8 MLEIIEAIYKMVGTVIMMRMNQDGLTPQQRVDKIFKKMDQDKDDQITLEEFKEAAKSDPS ::.:..:::.:::... . ... ::..:::.:: ::.. : ..::.::.:..:.::: CCDS78 MLDIVDAIYQMVGNTVELPEEEN--TPEKRVDRIFAMMDKNADGKLTLQEFQEGSKADPS 110 120 130 140 150 160 190 pF1KB8 IVLLLQCDMQK :: : CCDS78 IVQALSLYDGLV 170 >>CCDS11151.1 RCVRN gene_id:5957|Hs108|chr17 (200 aa) initn: 600 init1: 600 opt: 609 Z-score: 677.5 bits: 132.2 E(32554): 2e-31 Smith-Waterman score: 609; 45.8% identity (78.1% similar) in 192 aa overlap (1-191:1-192) 10 20 30 40 50 pF1KB8 MGKTNS-KLAPEVLEDLVQNTEFSEQELKQWYKGFLKDCPSGILNLEEFQQLYIKFFPYG ::...: :. :.::.: ::.:::.:: .::..::::::.: .. ..::..: :::: CCDS11 MGNSKSGALSKEILEELQLNTKFSEEELCSWYQSFLKDCPTGRITQQQFQSIYAKFFPDT 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB8 DASKFAQHAFRTFDKNGDGTIDFREFICALSVTSRGSFEQKLNWAFEMYDLDGDGRITRL : . .:::.::.::.: :::.::.:.. :: .:. :. .:::.::: .::.::.: :.. CCDS11 DPKAYAQHVFRSFDSNLDGTLDFKEYVIALHMTTAGKTNQKLEWAFSLYDVDGNGTISKN 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB8 EMLEIIEAIYKMVGTVIMMRMNQDGLTPQQRVDKIFKKMDQDKDDQITLEEFKEAAKSDP :.:::. ::.::. . . .: ::..:..::.: . .. ::..: .:: :.. .. CCDS11 EVLEIVMAIFKMITPEDVKLLPDDENTPEKRAEKIWKYFGKNDDDKLTEKEFIEGTLANK 130 140 150 160 170 180 180 190 pF1KB8 SIVLLLQCDMQK :. :.: . :: CCDS11 EILRLIQFEPQKVKEKMKNA 190 200 >>CCDS64313.1 KCNIP1 gene_id:30820|Hs108|chr5 (188 aa) initn: 551 init1: 433 opt: 555 Z-score: 619.1 bits: 121.3 E(32554): 3.7e-28 Smith-Waterman score: 555; 43.5% identity (76.8% similar) in 177 aa overlap (10-186:8-182) 10 20 30 40 50 60 pF1KB8 MGKTNSKLAPEVLEDLVQNTEFSEQELKQWYKGFLKDCPSGILNLEEFQQLYIKFFPYGD :: ::.: .:.:...::. :.:: ..::::..: . :.:.: .:::.:: CCDS64 MTMVCHRPEGLEQLEAQTNFTKRELQVLYRGFKNECPSGVVNEDTFKQIYAQFFPHGD 10 20 30 40 50 70 80 90 100 110 120 pF1KB8 ASKFAQHAFRTFDKNGDGTIDFREFICALSVTSRGSFEQKLNWAFEMYDLDGDGRITRLE :: .:.. : .:: . :.. :..:. :::. ::. ..:: :.:..::.. :: :.. : CCDS64 ASTYAHYLFNAFDTTQTGSVKFEDFVTALSILLRGTVHEKLRWTFNLYDINKDGYINKEE 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB8 MLEIIEAIYKMVGTVIMMRMNQDGLTPQQRVDKIFKKMDQDKDDQITLEEFKEAAKSDPS :..:..::: :.: . ...: ::.:.:: .:.:::..:: .::.:: :. . : . CCDS64 MMDIVKAIYDMMGKYTYPVLKED--TPRQHVDVFFQKMDKNKDGIVTLDEFLESCQEDDN 120 130 140 150 160 170 190 pF1KB8 IVLLLQCDMQK :. :: CCDS64 IMRSLQLFQNVM 180 >>CCDS4374.1 KCNIP1 gene_id:30820|Hs108|chr5 (216 aa) initn: 551 init1: 433 opt: 555 Z-score: 618.3 bits: 121.3 E(32554): 4e-28 Smith-Waterman score: 555; 43.5% identity (76.8% similar) in 177 aa overlap (10-186:36-210) 10 20 30 pF1KB8 MGKTNSKLAPEVLEDLVQNTEFSEQELKQWYKGFLKDCP :: ::.: .:.:...::. :.:: ..:: CCDS43 GTFSSLQTKQRRPSKDKIEDELEMTMVCHRPEGLEQLEAQTNFTKRELQVLYRGFKNECP 10 20 30 40 50 60 40 50 60 70 80 90 pF1KB8 SGILNLEEFQQLYIKFFPYGDASKFAQHAFRTFDKNGDGTIDFREFICALSVTSRGSFEQ ::..: . :.:.: .:::.:::: .:.. : .:: . :.. :..:. :::. ::. .. CCDS43 SGVVNEDTFKQIYAQFFPHGDASTYAHYLFNAFDTTQTGSVKFEDFVTALSILLRGTVHE 70 80 90 100 110 120 100 110 120 130 140 150 pF1KB8 KLNWAFEMYDLDGDGRITRLEMLEIIEAIYKMVGTVIMMRMNQDGLTPQQRVDKIFKKMD :: :.:..::.. :: :.. ::..:..::: :.: . ...: ::.:.:: .:.::: CCDS43 KLRWTFNLYDINKDGYINKEEMMDIVKAIYDMMGKYTYPVLKED--TPRQHVDVFFQKMD 130 140 150 160 170 180 160 170 180 190 pF1KB8 QDKDDQITLEEFKEAAKSDPSIVLLLQCDMQK ..:: .::.:: :. . : .:. :: CCDS43 KNKDGIVTLDEFLESCQEDDNIMRSLQLFQNVM 190 200 210 191 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 02:07:44 2016 done: Sat Nov 5 02:07:45 2016 Total Scan time: 1.850 Total Display time: -0.010 Function used was FASTA [36.3.4 Apr, 2011]