FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB8301, 478 aa 1>>>pF1KB8301 478 - 478 aa - 478 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.5980+/-0.000356; mu= 16.4662+/- 0.022 mean_var=75.3133+/-14.793, 0's: 0 Z-trim(114.9): 12 B-trim: 49 in 1/50 Lambda= 0.147788 statistics sampled from 25083 (25093) to 25083 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.676), E-opt: 0.2 (0.294), width: 16 Scan time: 7.920 The best scores are: opt bits E(85289) NP_001291493 (OMIM: 615497) mitochondrial dynamics ( 478) 3188 689.2 6.4e-198 XP_011528539 (OMIM: 615497) PREDICTED: mitochondri ( 463) 2866 620.6 2.9e-177 XP_011528540 (OMIM: 615497) PREDICTED: mitochondri ( 463) 2866 620.6 2.9e-177 NP_061881 (OMIM: 615497) mitochondrial dynamics pr ( 463) 2866 620.6 2.9e-177 XP_011528538 (OMIM: 615497) PREDICTED: mitochondri ( 463) 2866 620.6 2.9e-177 XP_016884327 (OMIM: 615497) PREDICTED: mitochondri ( 463) 2866 620.6 2.9e-177 NP_631901 (OMIM: 615498) mitochondrial dynamics pr ( 454) 925 206.7 1.1e-52 XP_016879679 (OMIM: 615498) PREDICTED: mitochondri ( 461) 925 206.7 1.1e-52 NP_683684 (OMIM: 615498) mitochondrial dynamics pr ( 465) 925 206.7 1.1e-52 NP_001138372 (OMIM: 615498) mitochondrial dynamics ( 205) 263 65.4 1.7e-10 >>NP_001291493 (OMIM: 615497) mitochondrial dynamics pro (478 aa) initn: 3188 init1: 3188 opt: 3188 Z-score: 3674.3 bits: 689.2 E(85289): 6.4e-198 Smith-Waterman score: 3188; 99.6% identity (100.0% similar) in 478 aa overlap (1-478:1-478) 10 20 30 40 50 60 pF1KB8 MAGAGERKGKKDDNGIGTAIDFVLSNARLVLGVGGAAMLGIATLAVKRMYDRAISAPTSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MAGAGERKGKKDDNGIGTAIDFVLSNARLVLGVGGAAMLGIATLAVKRMYDRAISAPTSP 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 TRLSHSGKRSWEEPNWMGSPRLLNRDMKTGLSRSLQTLPTDSSTFDTDTFCPPRPKPVAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TRLSHSGKRSWEEPNWMGSPRLLNRDMKTGLSRSLQTLPTDSSTFDTDTFCPPRPKPVAR 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 KGQVDLKKSRLRMSLQEKLLTYYRNRAAIPAGEQARAKQAAVDICAELRSFLRAKLPDMP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KGQVDLKKSRLRMSLQEKLLTYYRNRAAIPAGEQARAKQAAVDICAELRSFLRAKLPDMP 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 LRDMYLSGSLYDDLQVVTADHIQLIVPLVLEQNLWSCIPGEDTIMNVPGFFLVRRENPEY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LRDMYLSGSLYDDLQVVTADHIQLIVPLVLEQNLWSCIPGEDTIMNVPGFFLVRRENPEY 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 FPRGSSYWDRCVVGGYLSPKTVANTFEKVVAGSINWPAIGSLLDYVIRPAPPPEALTLEV :::::::::::::::::::::::.:::::::::::::::::::::::::::::::::::: NP_001 FPRGSSYWDRCVVGGYLSPKTVADTFEKVVAGSINWPAIGSLLDYVIRPAPPPEALTLEV 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 QYERDKHLFIDFLPSVTLGDTVLVAKPHRLAQYDNLWRLSLRPAETARLRALDQADSGCR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QYERDKHLFIDFLPSVTLGDTVLVAKPHRLAQYDNLWRLSLRPAETARLRALDQADSGCR 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB8 SLCLKILKAICKSTPALGHLTASQLTNVILHLAQEEADWSPDMLADRFLQALRGLISYLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SLCLKILKAICKSTPALGHLTASQLTNVILHLAQEEADWSPDMLADRFLQALRGLISYLE 370 380 390 400 410 420 430 440 450 460 470 pF1KB8 AGVLPSALNPKDKALKERSLRYQVRMMEVDSRLNVSWKIQSLVGVWWPCFLPRQALLF :::::::::::::::::::::.:::::::::::::::::::::::::::::::::::: NP_001 AGVLPSALNPKDKALKERSLRHQVRMMEVDSRLNVSWKIQSLVGVWWPCFLPRQALLF 430 440 450 460 470 >>XP_011528539 (OMIM: 615497) PREDICTED: mitochondrial d (463 aa) initn: 2866 init1: 2866 opt: 2866 Z-score: 3303.5 bits: 620.6 E(85289): 2.9e-177 Smith-Waterman score: 2866; 99.8% identity (100.0% similar) in 431 aa overlap (1-431:1-431) 10 20 30 40 50 60 pF1KB8 MAGAGERKGKKDDNGIGTAIDFVLSNARLVLGVGGAAMLGIATLAVKRMYDRAISAPTSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MAGAGERKGKKDDNGIGTAIDFVLSNARLVLGVGGAAMLGIATLAVKRMYDRAISAPTSP 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 TRLSHSGKRSWEEPNWMGSPRLLNRDMKTGLSRSLQTLPTDSSTFDTDTFCPPRPKPVAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TRLSHSGKRSWEEPNWMGSPRLLNRDMKTGLSRSLQTLPTDSSTFDTDTFCPPRPKPVAR 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 KGQVDLKKSRLRMSLQEKLLTYYRNRAAIPAGEQARAKQAAVDICAELRSFLRAKLPDMP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KGQVDLKKSRLRMSLQEKLLTYYRNRAAIPAGEQARAKQAAVDICAELRSFLRAKLPDMP 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 LRDMYLSGSLYDDLQVVTADHIQLIVPLVLEQNLWSCIPGEDTIMNVPGFFLVRRENPEY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LRDMYLSGSLYDDLQVVTADHIQLIVPLVLEQNLWSCIPGEDTIMNVPGFFLVRRENPEY 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 FPRGSSYWDRCVVGGYLSPKTVANTFEKVVAGSINWPAIGSLLDYVIRPAPPPEALTLEV :::::::::::::::::::::::.:::::::::::::::::::::::::::::::::::: XP_011 FPRGSSYWDRCVVGGYLSPKTVADTFEKVVAGSINWPAIGSLLDYVIRPAPPPEALTLEV 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 QYERDKHLFIDFLPSVTLGDTVLVAKPHRLAQYDNLWRLSLRPAETARLRALDQADSGCR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QYERDKHLFIDFLPSVTLGDTVLVAKPHRLAQYDNLWRLSLRPAETARLRALDQADSGCR 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB8 SLCLKILKAICKSTPALGHLTASQLTNVILHLAQEEADWSPDMLADRFLQALRGLISYLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SLCLKILKAICKSTPALGHLTASQLTNVILHLAQEEADWSPDMLADRFLQALRGLISYLE 370 380 390 400 410 420 430 440 450 460 470 pF1KB8 AGVLPSALNPKDKALKERSLRYQVRMMEVDSRLNVSWKIQSLVGVWWPCFLPRQALLF ::::::::::: XP_011 AGVLPSALNPKVNLFAELTPEEIDELGYTLYCSLSEPEVLLQT 430 440 450 460 >>XP_011528540 (OMIM: 615497) PREDICTED: mitochondrial d (463 aa) initn: 2866 init1: 2866 opt: 2866 Z-score: 3303.5 bits: 620.6 E(85289): 2.9e-177 Smith-Waterman score: 2866; 99.8% identity (100.0% similar) in 431 aa overlap (1-431:1-431) 10 20 30 40 50 60 pF1KB8 MAGAGERKGKKDDNGIGTAIDFVLSNARLVLGVGGAAMLGIATLAVKRMYDRAISAPTSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MAGAGERKGKKDDNGIGTAIDFVLSNARLVLGVGGAAMLGIATLAVKRMYDRAISAPTSP 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 TRLSHSGKRSWEEPNWMGSPRLLNRDMKTGLSRSLQTLPTDSSTFDTDTFCPPRPKPVAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TRLSHSGKRSWEEPNWMGSPRLLNRDMKTGLSRSLQTLPTDSSTFDTDTFCPPRPKPVAR 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 KGQVDLKKSRLRMSLQEKLLTYYRNRAAIPAGEQARAKQAAVDICAELRSFLRAKLPDMP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KGQVDLKKSRLRMSLQEKLLTYYRNRAAIPAGEQARAKQAAVDICAELRSFLRAKLPDMP 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 LRDMYLSGSLYDDLQVVTADHIQLIVPLVLEQNLWSCIPGEDTIMNVPGFFLVRRENPEY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LRDMYLSGSLYDDLQVVTADHIQLIVPLVLEQNLWSCIPGEDTIMNVPGFFLVRRENPEY 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 FPRGSSYWDRCVVGGYLSPKTVANTFEKVVAGSINWPAIGSLLDYVIRPAPPPEALTLEV :::::::::::::::::::::::.:::::::::::::::::::::::::::::::::::: XP_011 FPRGSSYWDRCVVGGYLSPKTVADTFEKVVAGSINWPAIGSLLDYVIRPAPPPEALTLEV 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 QYERDKHLFIDFLPSVTLGDTVLVAKPHRLAQYDNLWRLSLRPAETARLRALDQADSGCR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QYERDKHLFIDFLPSVTLGDTVLVAKPHRLAQYDNLWRLSLRPAETARLRALDQADSGCR 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB8 SLCLKILKAICKSTPALGHLTASQLTNVILHLAQEEADWSPDMLADRFLQALRGLISYLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SLCLKILKAICKSTPALGHLTASQLTNVILHLAQEEADWSPDMLADRFLQALRGLISYLE 370 380 390 400 410 420 430 440 450 460 470 pF1KB8 AGVLPSALNPKDKALKERSLRYQVRMMEVDSRLNVSWKIQSLVGVWWPCFLPRQALLF ::::::::::: XP_011 AGVLPSALNPKVNLFAELTPEEIDELGYTLYCSLSEPEVLLQT 430 440 450 460 >>NP_061881 (OMIM: 615497) mitochondrial dynamics protei (463 aa) initn: 2866 init1: 2866 opt: 2866 Z-score: 3303.5 bits: 620.6 E(85289): 2.9e-177 Smith-Waterman score: 2866; 99.8% identity (100.0% similar) in 431 aa overlap (1-431:1-431) 10 20 30 40 50 60 pF1KB8 MAGAGERKGKKDDNGIGTAIDFVLSNARLVLGVGGAAMLGIATLAVKRMYDRAISAPTSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_061 MAGAGERKGKKDDNGIGTAIDFVLSNARLVLGVGGAAMLGIATLAVKRMYDRAISAPTSP 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 TRLSHSGKRSWEEPNWMGSPRLLNRDMKTGLSRSLQTLPTDSSTFDTDTFCPPRPKPVAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_061 TRLSHSGKRSWEEPNWMGSPRLLNRDMKTGLSRSLQTLPTDSSTFDTDTFCPPRPKPVAR 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 KGQVDLKKSRLRMSLQEKLLTYYRNRAAIPAGEQARAKQAAVDICAELRSFLRAKLPDMP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_061 KGQVDLKKSRLRMSLQEKLLTYYRNRAAIPAGEQARAKQAAVDICAELRSFLRAKLPDMP 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 LRDMYLSGSLYDDLQVVTADHIQLIVPLVLEQNLWSCIPGEDTIMNVPGFFLVRRENPEY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_061 LRDMYLSGSLYDDLQVVTADHIQLIVPLVLEQNLWSCIPGEDTIMNVPGFFLVRRENPEY 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 FPRGSSYWDRCVVGGYLSPKTVANTFEKVVAGSINWPAIGSLLDYVIRPAPPPEALTLEV :::::::::::::::::::::::.:::::::::::::::::::::::::::::::::::: NP_061 FPRGSSYWDRCVVGGYLSPKTVADTFEKVVAGSINWPAIGSLLDYVIRPAPPPEALTLEV 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 QYERDKHLFIDFLPSVTLGDTVLVAKPHRLAQYDNLWRLSLRPAETARLRALDQADSGCR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_061 QYERDKHLFIDFLPSVTLGDTVLVAKPHRLAQYDNLWRLSLRPAETARLRALDQADSGCR 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB8 SLCLKILKAICKSTPALGHLTASQLTNVILHLAQEEADWSPDMLADRFLQALRGLISYLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_061 SLCLKILKAICKSTPALGHLTASQLTNVILHLAQEEADWSPDMLADRFLQALRGLISYLE 370 380 390 400 410 420 430 440 450 460 470 pF1KB8 AGVLPSALNPKDKALKERSLRYQVRMMEVDSRLNVSWKIQSLVGVWWPCFLPRQALLF ::::::::::: NP_061 AGVLPSALNPKVNLFAELTPEEIDELGYTLYCSLSEPEVLLQT 430 440 450 460 >>XP_011528538 (OMIM: 615497) PREDICTED: mitochondrial d (463 aa) initn: 2866 init1: 2866 opt: 2866 Z-score: 3303.5 bits: 620.6 E(85289): 2.9e-177 Smith-Waterman score: 2866; 99.8% identity (100.0% similar) in 431 aa overlap (1-431:1-431) 10 20 30 40 50 60 pF1KB8 MAGAGERKGKKDDNGIGTAIDFVLSNARLVLGVGGAAMLGIATLAVKRMYDRAISAPTSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MAGAGERKGKKDDNGIGTAIDFVLSNARLVLGVGGAAMLGIATLAVKRMYDRAISAPTSP 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 TRLSHSGKRSWEEPNWMGSPRLLNRDMKTGLSRSLQTLPTDSSTFDTDTFCPPRPKPVAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TRLSHSGKRSWEEPNWMGSPRLLNRDMKTGLSRSLQTLPTDSSTFDTDTFCPPRPKPVAR 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 KGQVDLKKSRLRMSLQEKLLTYYRNRAAIPAGEQARAKQAAVDICAELRSFLRAKLPDMP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KGQVDLKKSRLRMSLQEKLLTYYRNRAAIPAGEQARAKQAAVDICAELRSFLRAKLPDMP 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 LRDMYLSGSLYDDLQVVTADHIQLIVPLVLEQNLWSCIPGEDTIMNVPGFFLVRRENPEY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LRDMYLSGSLYDDLQVVTADHIQLIVPLVLEQNLWSCIPGEDTIMNVPGFFLVRRENPEY 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 FPRGSSYWDRCVVGGYLSPKTVANTFEKVVAGSINWPAIGSLLDYVIRPAPPPEALTLEV :::::::::::::::::::::::.:::::::::::::::::::::::::::::::::::: XP_011 FPRGSSYWDRCVVGGYLSPKTVADTFEKVVAGSINWPAIGSLLDYVIRPAPPPEALTLEV 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 QYERDKHLFIDFLPSVTLGDTVLVAKPHRLAQYDNLWRLSLRPAETARLRALDQADSGCR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QYERDKHLFIDFLPSVTLGDTVLVAKPHRLAQYDNLWRLSLRPAETARLRALDQADSGCR 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB8 SLCLKILKAICKSTPALGHLTASQLTNVILHLAQEEADWSPDMLADRFLQALRGLISYLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SLCLKILKAICKSTPALGHLTASQLTNVILHLAQEEADWSPDMLADRFLQALRGLISYLE 370 380 390 400 410 420 430 440 450 460 470 pF1KB8 AGVLPSALNPKDKALKERSLRYQVRMMEVDSRLNVSWKIQSLVGVWWPCFLPRQALLF ::::::::::: XP_011 AGVLPSALNPKVNLFAELTPEEIDELGYTLYCSLSEPEVLLQT 430 440 450 460 >>XP_016884327 (OMIM: 615497) PREDICTED: mitochondrial d (463 aa) initn: 2866 init1: 2866 opt: 2866 Z-score: 3303.5 bits: 620.6 E(85289): 2.9e-177 Smith-Waterman score: 2866; 99.8% identity (100.0% similar) in 431 aa overlap (1-431:1-431) 10 20 30 40 50 60 pF1KB8 MAGAGERKGKKDDNGIGTAIDFVLSNARLVLGVGGAAMLGIATLAVKRMYDRAISAPTSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MAGAGERKGKKDDNGIGTAIDFVLSNARLVLGVGGAAMLGIATLAVKRMYDRAISAPTSP 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 TRLSHSGKRSWEEPNWMGSPRLLNRDMKTGLSRSLQTLPTDSSTFDTDTFCPPRPKPVAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TRLSHSGKRSWEEPNWMGSPRLLNRDMKTGLSRSLQTLPTDSSTFDTDTFCPPRPKPVAR 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 KGQVDLKKSRLRMSLQEKLLTYYRNRAAIPAGEQARAKQAAVDICAELRSFLRAKLPDMP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KGQVDLKKSRLRMSLQEKLLTYYRNRAAIPAGEQARAKQAAVDICAELRSFLRAKLPDMP 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 LRDMYLSGSLYDDLQVVTADHIQLIVPLVLEQNLWSCIPGEDTIMNVPGFFLVRRENPEY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LRDMYLSGSLYDDLQVVTADHIQLIVPLVLEQNLWSCIPGEDTIMNVPGFFLVRRENPEY 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 FPRGSSYWDRCVVGGYLSPKTVANTFEKVVAGSINWPAIGSLLDYVIRPAPPPEALTLEV :::::::::::::::::::::::.:::::::::::::::::::::::::::::::::::: XP_016 FPRGSSYWDRCVVGGYLSPKTVADTFEKVVAGSINWPAIGSLLDYVIRPAPPPEALTLEV 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 QYERDKHLFIDFLPSVTLGDTVLVAKPHRLAQYDNLWRLSLRPAETARLRALDQADSGCR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QYERDKHLFIDFLPSVTLGDTVLVAKPHRLAQYDNLWRLSLRPAETARLRALDQADSGCR 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB8 SLCLKILKAICKSTPALGHLTASQLTNVILHLAQEEADWSPDMLADRFLQALRGLISYLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SLCLKILKAICKSTPALGHLTASQLTNVILHLAQEEADWSPDMLADRFLQALRGLISYLE 370 380 390 400 410 420 430 440 450 460 470 pF1KB8 AGVLPSALNPKDKALKERSLRYQVRMMEVDSRLNVSWKIQSLVGVWWPCFLPRQALLF ::::::::::: XP_016 AGVLPSALNPKVNLFAELTPEEIDELGYTLYCSLSEPEVLLQT 430 440 450 460 >>NP_631901 (OMIM: 615498) mitochondrial dynamics protei (454 aa) initn: 1090 init1: 585 opt: 925 Z-score: 1067.0 bits: 206.7 E(85289): 1.1e-52 Smith-Waterman score: 1115; 45.2% identity (71.6% similar) in 436 aa overlap (1-430:1-423) 10 20 30 40 50 pF1KB8 MAGAGERKGKK-DDNGIGTAIDFVLSNARLVLGVGGAAMLGIATLAVKRMYDRAISAPTS :: ....::. .:.:.:. .::.:.::::::::::::.::::::::::. ::: :: NP_631 MAEFSQKRGKRRSDEGLGSMVDFLLANARLVLGVGGAAVLGIATLAVKRFIDRA----TS 10 20 30 40 50 60 70 80 90 100 110 pF1KB8 PTRLSHSGKRSWEEPNWM-GSPRLLNRDMKTGLSRSLQTLPTDSSTFDTDTFCPPRPKPV : . . ::.: . . ..:.: : ..::. . : .::. . . :. : NP_631 PRDEDDTKADSWKELSLLKATPHLQPRPPPAALSQPVLPLAPSSSAPEGPAETDPEVTP- 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB8 ARKGQVDLKKSRLRMSLQEKLLTYYRNRAAIPAGEQARAKQAAVDICAELRSFLRAKLPD :.. . . : ..:::.::.. :.:..:::.. : ::: : :: ::....:.:.:. NP_631 ----QLS-SPAPLCLTLQERLLAFERDRVTIPAAQVALAKQLAGDIALELQAYFRSKFPE 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB8 MPLRDMYLSGSLYDDLQVVTADHIQLIVPLVLEQNLWSCIPGEDTIMNVPGFFLVRRENP .:. . .: ::: ::. .:::..:.:::::: .::: .:: ::. : . ::: . NP_631 LPFGAFVPGGPLYDGLQAGAADHVRLLVPLVLEPGLWSLVPGVDTVARDPRCWAVRRTQL 180 190 200 210 220 230 240 250 260 270 280 290 pF1KB8 EYFPRGSSYWDRCVVGGYLSPKTVANTFEKVVAGSINWPAIGSLLDYVIRPAPPPEALTL :. ::::: ::: .:::::: ... . ..:..:.:.::::::::: .:::. : : : NP_631 EFCPRGSSPWDRFLVGGYLSSRVLLELLRKALAASVNWPAIGSLLGCLIRPSMASEELLL 240 250 260 270 280 290 300 310 320 330 340 350 pF1KB8 EVQYERDKHLFIDFL---PSVTLGDTVLVAKPHR-LAQYDNLWRLSLRPAETARLRALDQ :::.:: . : . : :.: : .:.: : . :: ::: .: :.:.:::::::. NP_631 EVQHERLE-LTVAVLVAVPGVDADDRLLLAWPLEGLA--GNLWLQDLYPVEAARLRALDD 300 310 320 330 340 360 370 380 390 400 410 pF1KB8 ADSGCRSLCLKILKAICKSTPALGHLTASQLTNVILHLAQEEADWSPDMLADRFLQALRG :.: : : .: :.:.. :::.: ..::.:.:.:.....::. . :..::::::. NP_631 HDAGTRRRLLLLLCAVCRGCSALGQLGRGHLTQVVLRLGEDNVDWTEEALGERFLQALEL 350 360 370 380 390 400 420 430 440 450 460 470 pF1KB8 LISYLEAGVLPSALNPKDKALKERSLRYQVRMMEVDSRLNVSWKIQSLVGVWWPCFLPRQ ::. :: . :: .:: NP_631 LIGSLEQASLPCHFNPSVNLFSSLREEEIDDIGYALYSGLQEPEGLL 410 420 430 440 450 >>XP_016879679 (OMIM: 615498) PREDICTED: mitochondrial d (461 aa) initn: 1090 init1: 585 opt: 925 Z-score: 1066.9 bits: 206.7 E(85289): 1.1e-52 Smith-Waterman score: 1115; 45.2% identity (71.6% similar) in 436 aa overlap (1-430:8-430) 10 20 30 40 50 pF1KB8 MAGAGERKGKK-DDNGIGTAIDFVLSNARLVLGVGGAAMLGIATLAVKRMYDR :: ....::. .:.:.:. .::.:.::::::::::::.::::::::::. :: XP_016 MPSYRQTMAEFSQKRGKRRSDEGLGSMVDFLLANARLVLGVGGAAVLGIATLAVKRFIDR 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB8 AISAPTSPTRLSHSGKRSWEEPNWM-GSPRLLNRDMKTGLSRSLQTLPTDSSTFDTDTFC : ::: . . ::.: . . ..:.: : ..::. . : .::. . . XP_016 A----TSPRDEDDTKADSWKELSLLKATPHLQPRPPPAALSQPVLPLAPSSSAPEGPAET 70 80 90 100 110 120 130 140 150 160 170 pF1KB8 PPRPKPVARKGQVDLKKSRLRMSLQEKLLTYYRNRAAIPAGEQARAKQAAVDICAELRSF :. : :.. . . : ..:::.::.. :.:..:::.. : ::: : :: ::... XP_016 DPEVTP-----QLS-SPAPLCLTLQERLLAFERDRVTIPAAQVALAKQLAGDIALELQAY 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB8 LRAKLPDMPLRDMYLSGSLYDDLQVVTADHIQLIVPLVLEQNLWSCIPGEDTIMNVPGFF .:.:.:..:. . .: ::: ::. .:::..:.:::::: .::: .:: ::. : . XP_016 FRSKFPELPFGAFVPGGPLYDGLQAGAADHVRLLVPLVLEPGLWSLVPGVDTVARDPRCW 180 190 200 210 220 230 240 250 260 270 280 290 pF1KB8 LVRRENPEYFPRGSSYWDRCVVGGYLSPKTVANTFEKVVAGSINWPAIGSLLDYVIRPAP ::: . :. ::::: ::: .:::::: ... . ..:..:.:.::::::::: .:::. XP_016 AVRRTQLEFCPRGSSPWDRFLVGGYLSSRVLLELLRKALAASVNWPAIGSLLGCLIRPSM 240 250 260 270 280 290 300 310 320 330 340 pF1KB8 PPEALTLEVQYERDKHLFIDFL---PSVTLGDTVLVAKPHR-LAQYDNLWRLSLRPAETA : : ::::.:: . : . : :.: : .:.: : . :: ::: .: :.:.: XP_016 ASEELLLEVQHERLE-LTVAVLVAVPGVDADDRLLLAWPLEGLA--GNLWLQDLYPVEAA 300 310 320 330 340 350 360 370 380 390 400 pF1KB8 RLRALDQADSGCRSLCLKILKAICKSTPALGHLTASQLTNVILHLAQEEADWSPDMLADR ::::::. :.: : : .: :.:.. :::.: ..::.:.:.:.....::. . :..: XP_016 RLRALDDHDAGTRRRLLLLLCAVCRGCSALGQLGRGHLTQVVLRLGEDNVDWTEEALGER 350 360 370 380 390 400 410 420 430 440 450 460 pF1KB8 FLQALRGLISYLEAGVLPSALNPKDKALKERSLRYQVRMMEVDSRLNVSWKIQSLVGVWW :::::. ::. :: . :: .:: XP_016 FLQALELLIGSLEQASLPCHFNPSVNLFSSLREEEIDDIGYALYSGLQEPEGLL 410 420 430 440 450 460 >>NP_683684 (OMIM: 615498) mitochondrial dynamics protei (465 aa) initn: 1090 init1: 585 opt: 925 Z-score: 1066.8 bits: 206.7 E(85289): 1.1e-52 Smith-Waterman score: 1115; 45.2% identity (71.6% similar) in 436 aa overlap (1-430:12-434) 10 20 30 40 pF1KB8 MAGAGERKGKK-DDNGIGTAIDFVLSNARLVLGVGGAAMLGIATLAVKR :: ....::. .:.:.:. .::.:.::::::::::::.:::::::::: NP_683 MGLSPNLDRQTMAEFSQKRGKRRSDEGLGSMVDFLLANARLVLGVGGAAVLGIATLAVKR 10 20 30 40 50 60 50 60 70 80 90 100 pF1KB8 MYDRAISAPTSPTRLSHSGKRSWEEPNWM-GSPRLLNRDMKTGLSRSLQTLPTDSSTFDT . ::: ::: . . ::.: . . ..:.: : ..::. . : .::. . NP_683 FIDRA----TSPRDEDDTKADSWKELSLLKATPHLQPRPPPAALSQPVLPLAPSSSAPEG 70 80 90 100 110 110 120 130 140 150 160 pF1KB8 DTFCPPRPKPVARKGQVDLKKSRLRMSLQEKLLTYYRNRAAIPAGEQARAKQAAVDICAE . :. : :.. . . : ..:::.::.. :.:..:::.. : ::: : :: : NP_683 PAETDPEVTP-----QLS-SPAPLCLTLQERLLAFERDRVTIPAAQVALAKQLAGDIALE 120 130 140 150 160 170 170 180 190 200 210 220 pF1KB8 LRSFLRAKLPDMPLRDMYLSGSLYDDLQVVTADHIQLIVPLVLEQNLWSCIPGEDTIMNV :....:.:.:..:. . .: ::: ::. .:::..:.:::::: .::: .:: ::. NP_683 LQAYFRSKFPELPFGAFVPGGPLYDGLQAGAADHVRLLVPLVLEPGLWSLVPGVDTVARD 180 190 200 210 220 230 230 240 250 260 270 280 pF1KB8 PGFFLVRRENPEYFPRGSSYWDRCVVGGYLSPKTVANTFEKVVAGSINWPAIGSLLDYVI : . ::: . :. ::::: ::: .:::::: ... . ..:..:.:.::::::::: .: NP_683 PRCWAVRRTQLEFCPRGSSPWDRFLVGGYLSSRVLLELLRKALAASVNWPAIGSLLGCLI 240 250 260 270 280 290 290 300 310 320 330 340 pF1KB8 RPAPPPEALTLEVQYERDKHLFIDFL---PSVTLGDTVLVAKPHR-LAQYDNLWRLSLRP ::. : : ::::.:: . : . : :.: : .:.: : . :: ::: .: : NP_683 RPSMASEELLLEVQHERLE-LTVAVLVAVPGVDADDRLLLAWPLEGLA--GNLWLQDLYP 300 310 320 330 340 350 360 370 380 390 400 pF1KB8 AETARLRALDQADSGCRSLCLKILKAICKSTPALGHLTASQLTNVILHLAQEEADWSPDM .:.:::::::. :.: : : .: :.:.. :::.: ..::.:.:.:.....::. . NP_683 VEAARLRALDDHDAGTRRRLLLLLCAVCRGCSALGQLGRGHLTQVVLRLGEDNVDWTEEA 350 360 370 380 390 400 410 420 430 440 450 460 pF1KB8 LADRFLQALRGLISYLEAGVLPSALNPKDKALKERSLRYQVRMMEVDSRLNVSWKIQSLV :..::::::. ::. :: . :: .:: NP_683 LGERFLQALELLIGSLEQASLPCHFNPSVNLFSSLREEEIDDIGYALYSGLQEPEGLL 410 420 430 440 450 460 >>NP_001138372 (OMIM: 615498) mitochondrial dynamics pro (205 aa) initn: 273 init1: 217 opt: 263 Z-score: 309.3 bits: 65.4 E(85289): 1.7e-10 Smith-Waterman score: 263; 46.7% identity (72.4% similar) in 105 aa overlap (1-103:1-101) 10 20 30 40 50 pF1KB8 MAGAGERKGKK-DDNGIGTAIDFVLSNARLVLGVGGAAMLGIATLAVKRMYDRAISAPTS :: ....::. .:.:.:. .::.:.::::::::::::.::::::::::. ::: :: NP_001 MAEFSQKRGKRRSDEGLGSMVDFLLANARLVLGVGGAAVLGIATLAVKRFIDRA----TS 10 20 30 40 50 60 70 80 90 100 110 pF1KB8 PTRLSHSGKRSWEEPNWM-GSPRLLNRDMKTGLSRSLQTLPTDSSTFDTDTFCPPRPKPV : . . ::.: . . ..:.: : ..::. . : .:: NP_001 PRDEDDTKADSWKELSLLKATPHLQPRPPPAALSQPVLPLAPSSSAPGEAAGLRAGPCDH 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB8 ARKGQVDLKKSRLRMSLQEKLLTYYRNRAAIPAGEQARAKQAAVDICAELRSFLRAKLPD NP_001 PSSPGGFGQTAGWRHRPGAAGLLSEQVPGTALWGIRAWGAALRRAAGGGCGPCASPGATG 120 130 140 150 160 170 478 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 11:32:03 2016 done: Fri Nov 4 11:32:04 2016 Total Scan time: 7.920 Total Display time: 0.040 Function used was FASTA [36.3.4 Apr, 2011]