FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB8320, 129 aa
1>>>pF1KB8320 129 - 129 aa - 129 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.5778+/-0.000388; mu= 15.0844+/- 0.024
mean_var=71.4997+/-15.608, 0's: 0 Z-trim(114.5): 278 B-trim: 2645 in 3/51
Lambda= 0.151678
statistics sampled from 23921 (24311) to 23921 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.678), E-opt: 0.2 (0.285), width: 16
Scan time: 3.660
The best scores are: opt bits E(85289)
NP_056358 (OMIM: 179508) ras-related protein Rab-1 ( 129) 830 190.1 8.3e-49
XP_005264525 (OMIM: 179508) PREDICTED: ras-related ( 173) 426 101.8 4.2e-22
NP_004152 (OMIM: 179508) ras-related protein Rab-1 ( 205) 426 101.9 4.7e-22
NP_112243 (OMIM: 612565) ras-related protein Rab-1 ( 201) 390 94.0 1.1e-19
XP_016873867 (OMIM: 612565) PREDICTED: ras-related ( 237) 390 94.1 1.2e-19
XP_011519971 (OMIM: 613532) PREDICTED: ras-related ( 122) 312 76.7 1.1e-14
NP_057614 (OMIM: 613532) ras-related protein Rab-8 ( 207) 312 77.0 1.5e-14
NP_005361 (OMIM: 165040) ras-related protein Rab-8 ( 207) 308 76.1 2.8e-14
XP_011526322 (OMIM: 165040) PREDICTED: ras-related ( 215) 308 76.1 2.9e-14
NP_002861 (OMIM: 602672) ras-related protein Rab-1 ( 203) 298 73.9 1.3e-13
NP_001161078 (OMIM: 604199) ras-related protein Ra ( 152) 295 73.1 1.6e-13
NP_006852 (OMIM: 604199) ras-related protein Rab-3 ( 201) 295 73.2 2e-13
NP_057215 (OMIM: 612672) ras-related protein Rab-1 ( 200) 288 71.7 5.7e-13
NP_002857 (OMIM: 179490) ras-related protein Rab-3 ( 220) 242 61.7 6.5e-10
XP_011526466 (OMIM: 179490) PREDICTED: ras-related ( 220) 242 61.7 6.5e-10
NP_004274 (OMIM: 604350) ras-related protein Rab-3 ( 219) 241 61.5 7.6e-10
NP_001304844 (OMIM: 612829) ras-related protein Ra ( 225) 241 61.5 7.7e-10
NP_612462 (OMIM: 612829) ras-related protein Rab-3 ( 227) 241 61.5 7.8e-10
NP_001193765 (OMIM: 605570) ras-related protein Ra ( 155) 237 60.4 1.1e-09
XP_016857447 (OMIM: 179510) PREDICTED: ras-related ( 219) 238 60.8 1.2e-09
NP_002858 (OMIM: 179510) ras-related protein Rab-3 ( 219) 238 60.8 1.2e-09
NP_004654 (OMIM: 605570) ras-related protein Rab-1 ( 216) 237 60.6 1.4e-09
NP_004209 (OMIM: 604198) ras-related protein Rab-1 ( 218) 237 60.6 1.4e-09
XP_011520750 (OMIM: 605455) PREDICTED: ras-related ( 231) 222 57.3 1.4e-08
NP_055168 (OMIM: 605455) ras-related protein Rab-2 ( 256) 222 57.4 1.5e-08
NP_001272989 (OMIM: 605693) ras-related protein Ra ( 203) 220 56.8 1.7e-08
NP_055303 (OMIM: 605693) ras-related protein Rab-3 ( 203) 220 56.8 1.7e-08
NP_001272988 (OMIM: 605693) ras-related protein Ra ( 203) 220 56.8 1.7e-08
NP_001272990 (OMIM: 605693) ras-related protein Ra ( 203) 220 56.8 1.7e-08
NP_002856 (OMIM: 179509) ras-related protein Rab-2 ( 212) 220 56.9 1.8e-08
NP_116235 (OMIM: 607466) ras-related protein Rab-2 ( 216) 220 56.9 1.8e-08
NP_001020471 (OMIM: 616448) ras-related protein Ra ( 244) 215 55.8 4.2e-08
NP_001243341 (OMIM: 602207,614222) ras-related pro ( 142) 211 54.7 5.3e-08
NP_001243340 (OMIM: 602207,614222) ras-related pro ( 197) 211 54.9 6.6e-08
NP_067075 (OMIM: 602207,614222) ras-related protei ( 206) 211 54.9 6.9e-08
NP_001243339 (OMIM: 602207,614222) ras-related pro ( 235) 211 54.9 7.5e-08
NP_057238 (OMIM: 612945) ras-related protein Rab-4 ( 213) 206 53.8 1.5e-07
NP_001006639 (OMIM: 609956) ras-related protein Ra ( 223) 206 53.8 1.5e-07
NP_057406 (OMIM: 612673) ras-related protein Rab-1 ( 215) 199 52.3 4.4e-07
NP_004569 (OMIM: 179511) ras-related protein Rab-4 ( 218) 199 52.3 4.4e-07
NP_112586 (OMIM: 605950,615222) ras-related protei ( 229) 196 51.6 7.2e-07
XP_011530601 (OMIM: 605950,615222) PREDICTED: ras- ( 277) 196 51.7 8.2e-07
NP_001294982 (OMIM: 605455) ras-related protein Ra ( 190) 194 51.1 8.5e-07
NP_004785 (OMIM: 300333) ras-related protein Rab-3 ( 237) 194 51.2 1e-06
XP_011524433 (OMIM: 603869) PREDICTED: ras-related ( 182) 189 50.0 1.8e-06
XP_006722581 (OMIM: 603869) PREDICTED: ras-related ( 182) 189 50.0 1.8e-06
XP_005266790 (OMIM: 603869) PREDICTED: ras-related ( 218) 189 50.1 2e-06
XP_016881402 (OMIM: 603869) PREDICTED: ras-related ( 218) 189 50.1 2e-06
NP_004154 (OMIM: 603869) ras-related protein Rab-2 ( 218) 189 50.1 2e-06
XP_016881403 (OMIM: 603869) PREDICTED: ras-related ( 218) 189 50.1 2e-06
>>NP_056358 (OMIM: 179508) ras-related protein Rab-1A is (129 aa)
initn: 830 init1: 830 opt: 830 Z-score: 997.2 bits: 190.1 E(85289): 8.3e-49
Smith-Waterman score: 830; 100.0% identity (100.0% similar) in 129 aa overlap (1-129:1-129)
10 20 30 40 50 60
pF1KB8 MSSMNPEYDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 MSSMNPEYDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 KLQIEFADSLGIPFLETSAKNATNVEQSFMTMAAEIKKRMGPGATAGGAEKSNVKIQSTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 KLQIEFADSLGIPFLETSAKNATNVEQSFMTMAAEIKKRMGPGATAGGAEKSNVKIQSTP
70 80 90 100 110 120
pF1KB8 VKQSGGGCC
:::::::::
NP_056 VKQSGGGCC
>>XP_005264525 (OMIM: 179508) PREDICTED: ras-related pro (173 aa)
initn: 425 init1: 423 opt: 426 Z-score: 517.8 bits: 101.8 E(85289): 4.2e-22
Smith-Waterman score: 648; 72.7% identity (72.7% similar) in 161 aa overlap (13-129:13-173)
10 20 30 40 50 60
pF1KB8 MSSMNPEYDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTI
::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MSSMNPEYDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTI
10 20 30 40 50 60
70
pF1KB8 KLQIE--------------------------------------------FADSLGIPFLE
::::: :::::::::::
XP_005 KLQIESFNNVKQWLQEIDRYASENVNKLLVGNKCDLTTKKVVDYTTAKEFADSLGIPFLE
70 80 90 100 110 120
80 90 100 110 120
pF1KB8 TSAKNATNVEQSFMTMAAEIKKRMGPGATAGGAEKSNVKIQSTPVKQSGGGCC
:::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TSAKNATNVEQSFMTMAAEIKKRMGPGATAGGAEKSNVKIQSTPVKQSGGGCC
130 140 150 160 170
>>NP_004152 (OMIM: 179508) ras-related protein Rab-1A is (205 aa)
initn: 816 init1: 423 opt: 426 Z-score: 516.9 bits: 101.9 E(85289): 4.7e-22
Smith-Waterman score: 426; 71.0% identity (84.0% similar) in 100 aa overlap (30-129:111-205)
10 20 30 40 50
pF1KB8 MSSMNPEYDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKT
:.:... .. ... :. . . .: :
NP_004 YRGAHGIIVVYDVTDQESFNNVKQWLQEIDRYASENVNKLLVGN-KCDLTTKKV-VDYTT
90 100 110 120 130
60 70 80 90 100 110
pF1KB8 IKLQIEFADSLGIPFLETSAKNATNVEQSFMTMAAEIKKRMGPGATAGGAEKSNVKIQST
: :::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 AK---EFADSLGIPFLETSAKNATNVEQSFMTMAAEIKKRMGPGATAGGAEKSNVKIQST
140 150 160 170 180 190
120
pF1KB8 PVKQSGGGCC
::::::::::
NP_004 PVKQSGGGCC
200
>--
initn: 416 init1: 407 opt: 407 Z-score: 494.5 bits: 97.8 E(85289): 8.4e-21
Smith-Waterman score: 407; 100.0% identity (100.0% similar) in 64 aa overlap (1-64:1-64)
10 20 30 40 50 60
pF1KB8 MSSMNPEYDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 MSSMNPEYDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 KLQIEFADSLGIPFLETSAKNATNVEQSFMTMAAEIKKRMGPGATAGGAEKSNVKIQSTP
::::
NP_004 KLQIWDTAGQERFRTITSSYYRGAHGIIVVYDVTDQESFNNVKQWLQEIDRYASENVNKL
70 80 90 100 110 120
>>NP_112243 (OMIM: 612565) ras-related protein Rab-1B [H (201 aa)
initn: 641 init1: 390 opt: 390 Z-score: 474.5 bits: 94.0 E(85289): 1.1e-19
Smith-Waterman score: 390; 100.0% identity (100.0% similar) in 61 aa overlap (4-64:1-61)
10 20 30 40 50 60
pF1KB8 MSSMNPEYDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTI
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_112 MNPEYDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTI
10 20 30 40 50
70 80 90 100 110 120
pF1KB8 KLQIEFADSLGIPFLETSAKNATNVEQSFMTMAAEIKKRMGPGATAGGAEKSNVKIQSTP
::::
NP_112 KLQIWDTAGQERFRTITSSYYRGAHGIIVVYDVTDQESYANVKQWLQEIDRYASENVNKL
60 70 80 90 100 110
>--
initn: 275 init1: 265 opt: 367 Z-score: 447.3 bits: 89.0 E(85289): 3.6e-18
Smith-Waterman score: 367; 61.0% identity (83.0% similar) in 100 aa overlap (30-129:108-201)
10 20 30 40 50
pF1KB8 MSSMNPEYDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKT
:.:... .. ... . :. . . .:. :
NP_112 YRGAHGIIVVYDVTDQESYANVKQWLQEIDRYASENVNKLLVGNKS-DLTTKKV-VDNTT
80 90 100 110 120 130
60 70 80 90 100 110
pF1KB8 IKLQIEFADSLGIPFLETSAKNATNVEQSFMTMAAEIKKRMGPGATAGGAEKSNVKIQST
: :::::::::::::::::::::::.::::::::::::::::..:: :. :.::.::
NP_112 AK---EFADSLGIPFLETSAKNATNVEQAFMTMAAEIKKRMGPGAASGG-ERPNLKIDST
140 150 160 170 180 190
120
pF1KB8 PVKQSGGGCC
::: .:::::
NP_112 PVKPAGGGCC
200
>>XP_016873867 (OMIM: 612565) PREDICTED: ras-related pro (237 aa)
initn: 641 init1: 390 opt: 390 Z-score: 473.6 bits: 94.1 E(85289): 1.2e-19
Smith-Waterman score: 390; 100.0% identity (100.0% similar) in 61 aa overlap (4-64:1-61)
10 20 30 40 50 60
pF1KB8 MSSMNPEYDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTI
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MNPEYDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTI
10 20 30 40 50
70 80 90 100 110 120
pF1KB8 KLQIEFADSLGIPFLETSAKNATNVEQSFMTMAAEIKKRMGPGATAGGAEKSNVKIQSTP
::::
XP_016 KLQIWDTAGQERFRTITSSYYRGAHGIIVVYDVTDQESYANVKQWLQEIDRYASENVNKL
60 70 80 90 100 110
>--
initn: 275 init1: 265 opt: 361 Z-score: 439.3 bits: 87.8 E(85289): 9.9e-18
Smith-Waterman score: 361; 84.6% identity (95.4% similar) in 65 aa overlap (65-129:174-237)
40 50 60 70 80 90
pF1KB8 TYTESYISTIGVDFKIRTIELDGKTIKLQIEFADSLGIPFLETSAKNATNVEQSFMTMAA
:::::::::::::::::::::::.::::::
XP_016 CPGSGRWGLLPLTCSPLLFSPLLFSPLPCQEFADSLGIPFLETSAKNATNVEQAFMTMAA
150 160 170 180 190 200
100 110 120
pF1KB8 EIKKRMGPGATAGGAEKSNVKIQSTPVKQSGGGCC
::::::::::..:: :. :.::.::::: .:::::
XP_016 EIKKRMGPGAASGG-ERPNLKIDSTPVKPAGGGCC
210 220 230
>>XP_011519971 (OMIM: 613532) PREDICTED: ras-related pro (122 aa)
initn: 324 init1: 312 opt: 312 Z-score: 384.9 bits: 76.7 E(85289): 1.1e-14
Smith-Waterman score: 312; 75.4% identity (91.8% similar) in 61 aa overlap (4-64:1-61)
10 20 30 40 50 60
pF1KB8 MSSMNPEYDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTI
: :::::::::::::::::.:::.::..:... ..:::::.:::::::::::: :
XP_011 MAKTYDYLFKLLLIGDSGVGKTCLLFRFSEDAFNTTFISTIGIDFKIRTIELDGKKI
10 20 30 40 50
70 80 90 100 110 120
pF1KB8 KLQIEFADSLGIPFLETSAKNATNVEQSFMTMAAEIKKRMGPGATAGGAEKSNVKIQSTP
::::
XP_011 KLQIWDTAGQERFRTITTAYYRGAMPCHHYLLPHHLHNIHCCGSSPCHPPDHHSASWPER
60 70 80 90 100 110
>>NP_057614 (OMIM: 613532) ras-related protein Rab-8B [H (207 aa)
initn: 402 init1: 312 opt: 312 Z-score: 382.1 bits: 77.0 E(85289): 1.5e-14
Smith-Waterman score: 312; 75.4% identity (91.8% similar) in 61 aa overlap (4-64:1-61)
10 20 30 40 50 60
pF1KB8 MSSMNPEYDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTI
: :::::::::::::::::.:::.::..:... ..:::::.:::::::::::: :
NP_057 MAKTYDYLFKLLLIGDSGVGKTCLLFRFSEDAFNTTFISTIGIDFKIRTIELDGKKI
10 20 30 40 50
70 80 90 100 110 120
pF1KB8 KLQIEFADSLGIPFLETSAKNATNVEQSFMTMAAEIKKRMGPGATAGGAEKSNVKIQSTP
::::
NP_057 KLQIWDTAGQERFRTITTAYYRGAMGIMLVYDITNEKSFDNIKNWIRNIEEHASSDVERM
60 70 80 90 100 110
>>NP_005361 (OMIM: 165040) ras-related protein Rab-8A [H (207 aa)
initn: 423 init1: 308 opt: 308 Z-score: 377.3 bits: 76.1 E(85289): 2.8e-14
Smith-Waterman score: 308; 73.8% identity (91.8% similar) in 61 aa overlap (4-64:1-61)
10 20 30 40 50 60
pF1KB8 MSSMNPEYDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTI
: :::::::::::::::::.:.:.::..:... ..:::::.:::::::::::: :
NP_005 MAKTYDYLFKLLLIGDSGVGKTCVLFRFSEDAFNSTFISTIGIDFKIRTIELDGKRI
10 20 30 40 50
70 80 90 100 110 120
pF1KB8 KLQIEFADSLGIPFLETSAKNATNVEQSFMTMAAEIKKRMGPGATAGGAEKSNVKIQSTP
::::
NP_005 KLQIWDTAGQERFRTITTAYYRGAMGIMLVYDITNEKSFDNIRNWIRNIEEHASADVEKM
60 70 80 90 100 110
>>XP_011526322 (OMIM: 165040) PREDICTED: ras-related pro (215 aa)
initn: 401 init1: 308 opt: 308 Z-score: 377.1 bits: 76.1 E(85289): 2.9e-14
Smith-Waterman score: 308; 73.8% identity (91.8% similar) in 61 aa overlap (4-64:1-61)
10 20 30 40 50 60
pF1KB8 MSSMNPEYDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTI
: :::::::::::::::::.:.:.::..:... ..:::::.:::::::::::: :
XP_011 MAKTYDYLFKLLLIGDSGVGKTCVLFRFSEDAFNSTFISTIGIDFKIRTIELDGKRI
10 20 30 40 50
70 80 90 100 110 120
pF1KB8 KLQIEFADSLGIPFLETSAKNATNVEQSFMTMAAEIKKRMGPGATAGGAEKSNVKIQSTP
::::
XP_011 KLQIWDTAGQERFRTITTAYYRGAMGIMLVYDITNEKSFDNIRNWIRNIEEHASADVEKM
60 70 80 90 100 110
>>NP_002861 (OMIM: 602672) ras-related protein Rab-13 is (203 aa)
initn: 365 init1: 294 opt: 298 Z-score: 365.6 bits: 73.9 E(85289): 1.3e-13
Smith-Waterman score: 298; 67.2% identity (93.4% similar) in 61 aa overlap (4-64:1-61)
10 20 30 40 50 60
pF1KB8 MSSMNPEYDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTI
: ::.::::::::::::::.::..:::.:.....::::::.::::::....:: :
NP_002 MAKAYDHLFKLLLIGDSGVGKTCLIIRFAEDNFNNTYISTIGIDFKIRTVDIEGKKI
10 20 30 40 50
70 80 90 100 110 120
pF1KB8 KLQIEFADSLGIPFLETSAKNATNVEQSFMTMAAEIKKRMGPGATAGGAEKSNVKIQSTP
:::.
NP_002 KLQVWDTAGQERFKTITTAYYRGAMGIILVYDITDEKSFENIQNWMKSIKENASAGVERL
60 70 80 90 100 110
129 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 11:43:18 2016 done: Fri Nov 4 11:43:19 2016
Total Scan time: 3.660 Total Display time: -0.020
Function used was FASTA [36.3.4 Apr, 2011]