FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB8321, 292 aa 1>>>pF1KB8321 292 - 292 aa - 292 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.3439+/- 0.001; mu= 14.4903+/- 0.060 mean_var=58.2313+/-11.573, 0's: 0 Z-trim(102.6): 27 B-trim: 0 in 0/51 Lambda= 0.168072 statistics sampled from 7032 (7043) to 7032 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.592), E-opt: 0.2 (0.216), width: 16 Scan time: 2.340 The best scores are: opt bits E(32554) CCDS4329.1 CNOT8 gene_id:9337|Hs108|chr5 ( 292) 1931 476.8 8.3e-135 CCDS6000.2 CNOT7 gene_id:29883|Hs108|chr8 ( 285) 1496 371.3 4.6e-103 CCDS55202.1 CNOT7 gene_id:29883|Hs108|chr8 ( 244) 1349 335.6 2.1e-92 CCDS78074.1 CNOT8 gene_id:9337|Hs108|chr5 ( 186) 1230 306.7 8.2e-84 CCDS75361.1 CNOT8 gene_id:9337|Hs108|chr5 ( 238) 886 223.4 1.3e-58 CCDS78075.1 CNOT8 gene_id:9337|Hs108|chr5 ( 128) 837 211.4 2.8e-55 >>CCDS4329.1 CNOT8 gene_id:9337|Hs108|chr5 (292 aa) initn: 1931 init1: 1931 opt: 1931 Z-score: 2533.7 bits: 476.8 E(32554): 8.3e-135 Smith-Waterman score: 1931; 99.7% identity (99.7% similar) in 292 aa overlap (1-292:1-292) 10 20 30 40 50 60 pF1KB8 MPAALVENSQVICEVWASNLEEEMRKIREIVLSYSYIAMDTEFPGVVVRPIGEFRSSIDY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 MPAALVENSQVICEVWASNLEEEMRKIREIVLSYSYIAMDTEFPGVVVRPIGEFRSSIDY 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 QYQLLRCNVDLLKIIQLGLTFTNEKGEYPSGINTWQFNFKFNLTEDMYSQDSIDLLANSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 QYQLLRCNVDLLKIIQLGLTFTNEKGEYPSGINTWQFNFKFNLTEDMYSQDSIDLLANSG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 LQFQKHEEEGIDTLHFAELLMTSGVVLCDNVKWLSFHSGYDFGYTVKLLTDSRLPEEEHE :::::::::::::::::::::::::::::::::::::::::::: ::::::::::::::: CCDS43 LQFQKHEEEGIDTLHFAELLMTSGVVLCDNVKWLSFHSGYDFGYMVKLLTDSRLPEEEHE 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 FFHILNLFFPSIYDVKYLMKSCKNLKGGLQEVADQLDLQRIGRQHQAGSDSLLTGMAFFR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 FFHILNLFFPSIYDVKYLMKSCKNLKGGLQEVADQLDLQRIGRQHQAGSDSLLTGMAFFR 190 200 210 220 230 240 250 260 270 280 290 pF1KB8 MKELFFEDSIDDAKYCGRLYGLGTGVAQKQNEDVDSAQEKMSILAIINNMQQ :::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 MKELFFEDSIDDAKYCGRLYGLGTGVAQKQNEDVDSAQEKMSILAIINNMQQ 250 260 270 280 290 >>CCDS6000.2 CNOT7 gene_id:29883|Hs108|chr8 (285 aa) initn: 1494 init1: 1494 opt: 1496 Z-score: 1963.8 bits: 371.3 E(32554): 4.6e-103 Smith-Waterman score: 1496; 76.8% identity (91.8% similar) in 280 aa overlap (1-280:1-280) 10 20 30 40 50 60 pF1KB8 MPAALVENSQVICEVWASNLEEEMRKIREIVLSYSYIAMDTEFPGVVVRPIGEFRSSIDY :::: :..:: :::::: ::.:::.:::... .:.:.::::::::::.::::::::. :: CCDS60 MPAATVDHSQRICEVWACNLDEEMKKIRQVIRKYNYVAMDTEFPGVVARPIGEFRSNADY 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 QYQLLRCNVDLLKIIQLGLTFTNEKGEYPSGINTWQFNFKFNLTEDMYSQDSIDLLANSG ::::::::::::::::::::: ::.:::: : .:::::::::::::::.::::.::..:: CCDS60 QYQLLRCNVDLLKIIQLGLTFMNEQGEYPPGTSTWQFNFKFNLTEDMYAQDSIELLTTSG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 LQFQKHEEEGIDTLHFAELLMTSGVVLCDNVKWLSFHSGYDFGYTVKLLTDSRLPEEEHE .::.:::::::.: .:::::::::::::..:::::::::::::: .:.::.: ::::: . CCDS60 IQFKKHEEEGIETQYFAELLMTSGVVLCEGVKWLSFHSGYDFGYLIKILTNSNLPEEELD 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 FFHILNLFFPSIYDVKYLMKSCKNLKGGLQEVADQLDLQRIGRQHQAGSDSLLTGMAFFR ::.:: :::: ::::::::::::::::::::::.::.:.::: ::::::::::::::::. CCDS60 FFEILRLFFPVIYDVKYLMKSCKNLKGGLQEVAEQLELERIGPQHQAGSDSLLTGMAFFK 190 200 210 220 230 240 250 260 270 280 290 pF1KB8 MKELFFEDSIDDAKYCGRLYGLGTGVAQKQNEDVDSAQEKMSILAIINNMQQ :.:.:::: ::::::::.:::::.: . :: .. .:. CCDS60 MREMFFEDHIDDAKYCGHLYGLGSGSSYVQNGTGNAYEEEANKQS 250 260 270 280 >>CCDS55202.1 CNOT7 gene_id:29883|Hs108|chr8 (244 aa) initn: 1395 init1: 1349 opt: 1349 Z-score: 1772.3 bits: 335.6 E(32554): 2.1e-92 Smith-Waterman score: 1349; 79.5% identity (93.9% similar) in 244 aa overlap (1-244:1-244) 10 20 30 40 50 60 pF1KB8 MPAALVENSQVICEVWASNLEEEMRKIREIVLSYSYIAMDTEFPGVVVRPIGEFRSSIDY :::: :..:: :::::: ::.:::.:::... .:.:.::::::::::.::::::::. :: CCDS55 MPAATVDHSQRICEVWACNLDEEMKKIRQVIRKYNYVAMDTEFPGVVARPIGEFRSNADY 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 QYQLLRCNVDLLKIIQLGLTFTNEKGEYPSGINTWQFNFKFNLTEDMYSQDSIDLLANSG ::::::::::::::::::::: ::.:::: : .:::::::::::::::.::::.::..:: CCDS55 QYQLLRCNVDLLKIIQLGLTFMNEQGEYPPGTSTWQFNFKFNLTEDMYAQDSIELLTTSG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 LQFQKHEEEGIDTLHFAELLMTSGVVLCDNVKWLSFHSGYDFGYTVKLLTDSRLPEEEHE .::.:::::::.: .:::::::::::::..:::::::::::::: .:.::.: ::::: . CCDS55 IQFKKHEEEGIETQYFAELLMTSGVVLCEGVKWLSFHSGYDFGYLIKILTNSNLPEEELD 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 FFHILNLFFPSIYDVKYLMKSCKNLKGGLQEVADQLDLQRIGRQHQAGSDSLLTGMAFFR ::.:: :::: ::::::::::::::::::::::.::.:.::: ::::::::::::::::. CCDS55 FFEILRLFFPVIYDVKYLMKSCKNLKGGLQEVAEQLELERIGPQHQAGSDSLLTGMAFFK 190 200 210 220 230 240 250 260 270 280 290 pF1KB8 MKELFFEDSIDDAKYCGRLYGLGTGVAQKQNEDVDSAQEKMSILAIINNMQQ :.:. CCDS55 MREV >>CCDS78074.1 CNOT8 gene_id:9337|Hs108|chr5 (186 aa) initn: 1230 init1: 1230 opt: 1230 Z-score: 1618.2 bits: 306.7 E(32554): 8.2e-84 Smith-Waterman score: 1230; 99.5% identity (99.5% similar) in 186 aa overlap (107-292:1-186) 80 90 100 110 120 130 pF1KB8 LGLTFTNEKGEYPSGINTWQFNFKFNLTEDMYSQDSIDLLANSGLQFQKHEEEGIDTLHF :::::::::::::::::::::::::::::: CCDS78 MYSQDSIDLLANSGLQFQKHEEEGIDTLHF 10 20 30 140 150 160 170 180 190 pF1KB8 AELLMTSGVVLCDNVKWLSFHSGYDFGYTVKLLTDSRLPEEEHEFFHILNLFFPSIYDVK :::::::::::::::::::::::::::: ::::::::::::::::::::::::::::::: CCDS78 AELLMTSGVVLCDNVKWLSFHSGYDFGYMVKLLTDSRLPEEEHEFFHILNLFFPSIYDVK 40 50 60 70 80 90 200 210 220 230 240 250 pF1KB8 YLMKSCKNLKGGLQEVADQLDLQRIGRQHQAGSDSLLTGMAFFRMKELFFEDSIDDAKYC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS78 YLMKSCKNLKGGLQEVADQLDLQRIGRQHQAGSDSLLTGMAFFRMKELFFEDSIDDAKYC 100 110 120 130 140 150 260 270 280 290 pF1KB8 GRLYGLGTGVAQKQNEDVDSAQEKMSILAIINNMQQ :::::::::::::::::::::::::::::::::::: CCDS78 GRLYGLGTGVAQKQNEDVDSAQEKMSILAIINNMQQ 160 170 180 >>CCDS75361.1 CNOT8 gene_id:9337|Hs108|chr5 (238 aa) initn: 886 init1: 886 opt: 886 Z-score: 1165.7 bits: 223.4 E(32554): 1.3e-58 Smith-Waterman score: 1453; 81.2% identity (81.2% similar) in 292 aa overlap (1-292:1-238) 10 20 30 40 50 60 pF1KB8 MPAALVENSQVICEVWASNLEEEMRKIREIVLSYSYIAMDTEFPGVVVRPIGEFRSSIDY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS75 MPAALVENSQVICEVWASNLEEEMRKIREIVLSYSYIAMDTEFPGVVVRPIGEFRSSIDY 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 QYQLLRCNVDLLKIIQLGLTFTNEKGEYPSGINTWQFNFKFNLTEDMYSQDSIDLLANSG :::::::::::::::::::::::::::::::::::::::::::: CCDS75 QYQLLRCNVDLLKIIQLGLTFTNEKGEYPSGINTWQFNFKFNLT---------------- 70 80 90 100 130 140 150 160 170 180 pF1KB8 LQFQKHEEEGIDTLHFAELLMTSGVVLCDNVKWLSFHSGYDFGYTVKLLTDSRLPEEEHE :::::: ::::::::::::::: CCDS75 --------------------------------------GYDFGYMVKLLTDSRLPEEEHE 110 120 190 200 210 220 230 240 pF1KB8 FFHILNLFFPSIYDVKYLMKSCKNLKGGLQEVADQLDLQRIGRQHQAGSDSLLTGMAFFR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS75 FFHILNLFFPSIYDVKYLMKSCKNLKGGLQEVADQLDLQRIGRQHQAGSDSLLTGMAFFR 130 140 150 160 170 180 250 260 270 280 290 pF1KB8 MKELFFEDSIDDAKYCGRLYGLGTGVAQKQNEDVDSAQEKMSILAIINNMQQ :::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS75 MKELFFEDSIDDAKYCGRLYGLGTGVAQKQNEDVDSAQEKMSILAIINNMQQ 190 200 210 220 230 >>CCDS78075.1 CNOT8 gene_id:9337|Hs108|chr5 (128 aa) initn: 837 init1: 837 opt: 837 Z-score: 1105.8 bits: 211.4 E(32554): 2.8e-55 Smith-Waterman score: 837; 100.0% identity (100.0% similar) in 127 aa overlap (166-292:2-128) 140 150 160 170 180 190 pF1KB8 FAELLMTSGVVLCDNVKWLSFHSGYDFGYTVKLLTDSRLPEEEHEFFHILNLFFPSIYDV :::::::::::::::::::::::::::::: CCDS78 MVKLLTDSRLPEEEHEFFHILNLFFPSIYDV 10 20 30 200 210 220 230 240 250 pF1KB8 KYLMKSCKNLKGGLQEVADQLDLQRIGRQHQAGSDSLLTGMAFFRMKELFFEDSIDDAKY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS78 KYLMKSCKNLKGGLQEVADQLDLQRIGRQHQAGSDSLLTGMAFFRMKELFFEDSIDDAKY 40 50 60 70 80 90 260 270 280 290 pF1KB8 CGRLYGLGTGVAQKQNEDVDSAQEKMSILAIINNMQQ ::::::::::::::::::::::::::::::::::::: CCDS78 CGRLYGLGTGVAQKQNEDVDSAQEKMSILAIINNMQQ 100 110 120 292 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 11:43:54 2016 done: Fri Nov 4 11:43:54 2016 Total Scan time: 2.340 Total Display time: -0.020 Function used was FASTA [36.3.4 Apr, 2011]