FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB8333, 313 aa 1>>>pF1KB8333 313 - 313 aa - 313 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.5266+/-0.000876; mu= 14.5295+/- 0.052 mean_var=67.8442+/-13.447, 0's: 0 Z-trim(106.2): 68 B-trim: 0 in 0/50 Lambda= 0.155710 statistics sampled from 8764 (8834) to 8764 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.659), E-opt: 0.2 (0.271), width: 16 Scan time: 1.620 The best scores are: opt bits E(32554) CCDS9623.1 DHRS1 gene_id:115817|Hs108|chr14 ( 313) 2085 477.3 6.7e-135 CCDS43864.1 HSDL2 gene_id:84263|Hs108|chr9 ( 418) 251 65.3 9.1e-11 >>CCDS9623.1 DHRS1 gene_id:115817|Hs108|chr14 (313 aa) initn: 2085 init1: 2085 opt: 2085 Z-score: 2535.3 bits: 477.3 E(32554): 6.7e-135 Smith-Waterman score: 2085; 99.7% identity (100.0% similar) in 313 aa overlap (1-313:1-313) 10 20 30 40 50 60 pF1KB8 MAAPMNGQVCVVTGASRGIGRGIALQLCKAGATVYITGRHLDTLRVVAQEAQSLGGQCVP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS96 MAAPMNGQVCVVTGASRGIGRGIALQLCKAGATVYITGRHLDTLRVVAQEAQSLGGQCVP 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 VVCDSSQESEVRSLFEQVDREQQGRLDVLVNNAYAGVQTILNTRNKAFWETPASMWDDIN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS96 VVCDSSQESEVRSLFEQVDREQQGRLDVLVNNAYAGVQTILNTRNKAFWETPASMWDDIN 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 NVGLRGHYFCSVYGARLMVPAGQGLIVVISSPGSLQYMFNVPYGVGKAACDKLAADCAHE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS96 NVGLRGHYFCSVYGARLMVPAGQGLIVVISSPGSLQYMFNVPYGVGKAACDKLAADCAHE 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 LRRHGVSCVSLWPGIVQTELLKEHMAKEEVLQDPVLKQFKSAFSSAETTELSGKCVVALA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS96 LRRHGVSCVSLWPGIVQTELLKEHMAKEEVLQDPVLKQFKSAFSSAETTELSGKCVVALA 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 TDPNILSLSGKVLPSCDLARRYGLRDVDGRPVQDYLSLSSVLSHVSGLGWLASYLPSFLR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS96 TDPNILSLSGKVLPSCDLARRYGLRDVDGRPVQDYLSLSSVLSHVSGLGWLASYLPSFLR 250 260 270 280 290 300 310 pF1KB8 VPRWIIALYTSKF ::.:::::::::: CCDS96 VPKWIIALYTSKF 310 >>CCDS43864.1 HSDL2 gene_id:84263|Hs108|chr9 (418 aa) initn: 189 init1: 96 opt: 251 Z-score: 306.8 bits: 65.3 E(32554): 9.1e-11 Smith-Waterman score: 257; 25.3% identity (57.4% similar) in 289 aa overlap (5-276:8-273) 10 20 30 40 50 pF1KB8 MAAPMNGQVCVVTGASRGIGRGIALQLCKAGATVYITGR----H---LDTLRVVAQE . : . .::::::::..:::. : ::.. :... : : :. ..:.: CCDS43 MLPNTGRLAGCTVFITGASRGIGKAIALKAAKDGANIVIAAKTAQPHPKLLGTIYTAAEE 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB8 AQSLGGQCVPVVCDSSQESEVRSLFEQVDREQQGRLDVLVNNAYAGVQTILNTRNKAFWE ...::. .: . : .:... . :.. .. : .:.::::: : .. :: . CCDS43 IEAVGGKALPCIVDVRDEQQISAAVEKAIKKFGG-IDILVNNASA--ISLTNT-----LD 70 80 90 100 110 120 130 140 150 160 pF1KB8 TPASMWDDINNVGLRGHYFCSVYGARLMVPAGQGLIVVISSPGSLQYMF---NVPYGVGK ::.. : . ::. :: :. : . . . :. :: : .:. .. . : ..: CCDS43 TPTKRLDLMMNVNTRGTYLASKACIPYLKKSKVAHILNISPPLNLNPVWFKQHCAYTIAK 120 130 140 150 160 170 170 180 190 200 210 220 pF1KB8 AACDKLAADCAHELRRHGVSCVSLWPGIVQTELLKEHMAKEEVLQDPVLKQFKSAFSSAE . . . :.:.. . .. .::: .: . : : ..: : .. :. . CCDS43 YGMSMYVLGMAEEFKGE-IAVNALWP---KTAI---HTAAMDMLGGPGIE------SQCR 180 190 200 210 230 240 250 260 270 280 pF1KB8 TTELSGKCVVALATDPNILSLSGKVLPSCDLARRYGLRDVD------GRPVQ-DYLSLSS ... . . .. :. :..:. . . .. .. :... : :.:.: :.. CCDS43 KVDIIADAAYSIFQKPK--SFTGNFVIDENILKEEGIENFDVYAIKPGHPLQPDFFLDEY 220 230 240 250 260 270 290 300 310 pF1KB8 VLSHVSGLGWLASYLPSFLRVPRWIIALYTSKF CCDS43 PEAVSKKVESTGAVPEFKEEKLQLQPKPRSGAVEETFRIVKDSLSDDVVKATQAIYLFEL 280 290 300 310 320 330 313 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 11:51:02 2016 done: Fri Nov 4 11:51:03 2016 Total Scan time: 1.620 Total Display time: -0.020 Function used was FASTA [36.3.4 Apr, 2011]