FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB8336, 491 aa 1>>>pF1KB8336 491 - 491 aa - 491 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 7.4779+/-0.000494; mu= 8.3924+/- 0.030 mean_var=210.7911+/-42.442, 0's: 0 Z-trim(116.4): 2144 B-trim: 114 in 1/49 Lambda= 0.088338 statistics sampled from 25255 (27574) to 25255 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.678), E-opt: 0.2 (0.323), width: 16 Scan time: 8.170 The best scores are: opt bits E(85289) NP_001308045 (OMIM: 165260) zinc finger and SCAN d ( 491) 3401 446.8 6.5e-125 XP_011525219 (OMIM: 165260) PREDICTED: zinc finger ( 491) 3401 446.8 6.5e-125 NP_862829 (OMIM: 165260) zinc finger and SCAN doma ( 491) 3401 446.8 6.5e-125 XP_006723255 (OMIM: 165260) PREDICTED: zinc finger ( 491) 3401 446.8 6.5e-125 XP_016882236 (OMIM: 165260) PREDICTED: zinc finger ( 327) 2295 305.7 1.3e-82 XP_011525220 (OMIM: 165260) PREDICTED: zinc finger ( 327) 2295 305.7 1.3e-82 XP_011540503 (OMIM: 611703) PREDICTED: zinc finger ( 452) 1105 154.2 7.5e-37 NP_085137 (OMIM: 611703) zinc finger protein 436 [ ( 470) 1105 154.2 7.7e-37 NP_001070663 (OMIM: 611703) zinc finger protein 43 ( 470) 1105 154.2 7.7e-37 NP_001276331 (OMIM: 604077) zinc finger protein 13 ( 616) 1104 154.2 1e-36 XP_016882731 (OMIM: 604077) PREDICTED: zinc finger ( 621) 1104 154.2 1e-36 XP_016882730 (OMIM: 604077) PREDICTED: zinc finger ( 628) 1104 154.2 1e-36 NP_001276330 (OMIM: 604077) zinc finger protein 13 ( 658) 1104 154.2 1e-36 XP_016882729 (OMIM: 604077) PREDICTED: zinc finger ( 658) 1104 154.2 1e-36 NP_003427 (OMIM: 604077) zinc finger protein 135 i ( 670) 1104 154.2 1.1e-36 XP_006723425 (OMIM: 604077) PREDICTED: zinc finger ( 670) 1104 154.2 1.1e-36 XP_006723426 (OMIM: 604077) PREDICTED: zinc finger ( 670) 1104 154.2 1.1e-36 XP_005259268 (OMIM: 604077) PREDICTED: zinc finger ( 670) 1104 154.2 1.1e-36 NP_009065 (OMIM: 604077) zinc finger protein 135 i ( 682) 1104 154.2 1.1e-36 NP_001273626 (OMIM: 194552) zinc finger protein 79 ( 474) 1092 152.5 2.4e-36 XP_006717342 (OMIM: 194552) PREDICTED: zinc finger ( 474) 1092 152.5 2.4e-36 NP_001273625 (OMIM: 194552) zinc finger protein 79 ( 474) 1092 152.5 2.4e-36 NP_001309189 (OMIM: 194552) zinc finger protein 79 ( 474) 1092 152.5 2.4e-36 NP_009066 (OMIM: 194552) zinc finger protein 79 is ( 498) 1092 152.5 2.5e-36 NP_001273627 (OMIM: 194552) zinc finger protein 79 ( 364) 1080 150.9 5.9e-36 NP_068735 (OMIM: 194544) zinc finger protein 70 [H ( 446) 1078 150.7 8e-36 XP_006722621 (OMIM: 609601) PREDICTED: zinc finger ( 553) 1067 149.4 2.4e-35 XP_011524531 (OMIM: 609601) PREDICTED: zinc finger ( 553) 1067 149.4 2.4e-35 XP_011524532 (OMIM: 609601) PREDICTED: zinc finger ( 553) 1067 149.4 2.4e-35 XP_011515622 (OMIM: 194526) PREDICTED: zinc finger ( 499) 1065 149.1 2.7e-35 XP_016869365 (OMIM: 194526) PREDICTED: zinc finger ( 499) 1065 149.1 2.7e-35 NP_001273699 (OMIM: 194526) zinc finger protein 34 ( 520) 1065 149.1 2.8e-35 XP_016881531 (OMIM: 609601) PREDICTED: zinc finger ( 534) 1065 149.1 2.9e-35 NP_001128650 (OMIM: 609601) zinc finger protein 39 ( 534) 1065 149.1 2.9e-35 XP_011524533 (OMIM: 609601) PREDICTED: zinc finger ( 534) 1065 149.1 2.9e-35 XP_011515617 (OMIM: 194526) PREDICTED: zinc finger ( 539) 1065 149.1 2.9e-35 XP_016869364 (OMIM: 194526) PREDICTED: zinc finger ( 539) 1065 149.1 2.9e-35 XP_011515618 (OMIM: 194526) PREDICTED: zinc finger ( 539) 1065 149.1 2.9e-35 NP_001273698 (OMIM: 194526) zinc finger protein 34 ( 539) 1065 149.1 2.9e-35 XP_011515620 (OMIM: 194526) PREDICTED: zinc finger ( 539) 1065 149.1 2.9e-35 XP_016869361 (OMIM: 194526) PREDICTED: zinc finger ( 560) 1065 149.2 2.9e-35 XP_016869363 (OMIM: 194526) PREDICTED: zinc finger ( 560) 1065 149.2 2.9e-35 XP_016869362 (OMIM: 194526) PREDICTED: zinc finger ( 560) 1065 149.2 2.9e-35 NP_085057 (OMIM: 194526) zinc finger protein 34 is ( 560) 1065 149.2 2.9e-35 XP_011515616 (OMIM: 194526) PREDICTED: zinc finger ( 560) 1065 149.2 2.9e-35 NP_001265221 (OMIM: 194510) zinc finger protein 3 ( 410) 1062 148.6 3.1e-35 XP_016868072 (OMIM: 194510) PREDICTED: zinc finger ( 410) 1062 148.6 3.1e-35 XP_006716174 (OMIM: 194510) PREDICTED: zinc finger ( 410) 1062 148.6 3.1e-35 XP_016868071 (OMIM: 194510) PREDICTED: zinc finger ( 410) 1062 148.6 3.1e-35 NP_001265220 (OMIM: 194510) zinc finger protein 3 ( 410) 1062 148.6 3.1e-35 >>NP_001308045 (OMIM: 165260) zinc finger and SCAN domai (491 aa) initn: 3401 init1: 3401 opt: 3401 Z-score: 2363.6 bits: 446.8 E(85289): 6.5e-125 Smith-Waterman score: 3401; 100.0% identity (100.0% similar) in 491 aa overlap (1-491:1-491) 10 20 30 40 50 60 pF1KB8 MAIPKHSLSPVPWEEDSFLQVKVEEEEEASLSQGGESSHDHIAHSEAARLRFRHFRYEEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MAIPKHSLSPVPWEEDSFLQVKVEEEEEASLSQGGESSHDHIAHSEAARLRFRHFRYEEA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 SGPHEALAHLRALCCQWLQPEAHSKEQILELLVLEQFLGALPPEIQAWVGAQSPKSGEEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SGPHEALAHLRALCCQWLQPEAHSKEQILELLVLEQFLGALPPEIQAWVGAQSPKSGEEA 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 AVLVEDLTQVLDKRGWDPGAEPTEASCKQSDLGESEPSNVTETLMGGVSLGPAFVKACEP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AVLVEDLTQVLDKRGWDPGAEPTEASCKQSDLGESEPSNVTETLMGGVSLGPAFVKACEP 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 EGSSERSGLSGEIWTKSVTQQIHFKKTSGPYKDVPTDQRGRESGASRNSSSAWPNLTSQE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EGSSERSGLSGEIWTKSVTQQIHFKKTSGPYKDVPTDQRGRESGASRNSSSAWPNLTSQE 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 KPPSEDKFDLVDAYGTEPPYTYSGKRSSKCRECRKMFQSASALEAHQKTHSRKTPYACSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KPPSEDKFDLVDAYGTEPPYTYSGKRSSKCRECRKMFQSASALEAHQKTHSRKTPYACSE 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 CGKAFSRSTHLAQHQVVHTGAKPHECKECGKAFSRVTHLTQHQRIHTGEKPYKCGECGKT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 CGKAFSRSTHLAQHQVVHTGAKPHECKECGKAFSRVTHLTQHQRIHTGEKPYKCGECGKT 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB8 FSRSTHLTQHQRVHTGERPYECDACGKAFSQSTHLTQHQRIHTGEKPYKCDACGRAFSDC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FSRSTHLTQHQRVHTGERPYECDACGKAFSQSTHLTQHQRIHTGEKPYKCDACGRAFSDC 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB8 SALIRHLRIHSGEKPYQCKVCPKAFAQSSSLIEHQRIHTGEKPYKCSDCGKAFSRSSALM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SALIRHLRIHSGEKPYQCKVCPKAFAQSSSLIEHQRIHTGEKPYKCSDCGKAFSRSSALM 430 440 450 460 470 480 490 pF1KB8 VHLRIHITVLQ ::::::::::: NP_001 VHLRIHITVLQ 490 >>XP_011525219 (OMIM: 165260) PREDICTED: zinc finger and (491 aa) initn: 3401 init1: 3401 opt: 3401 Z-score: 2363.6 bits: 446.8 E(85289): 6.5e-125 Smith-Waterman score: 3401; 100.0% identity (100.0% similar) in 491 aa overlap (1-491:1-491) 10 20 30 40 50 60 pF1KB8 MAIPKHSLSPVPWEEDSFLQVKVEEEEEASLSQGGESSHDHIAHSEAARLRFRHFRYEEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MAIPKHSLSPVPWEEDSFLQVKVEEEEEASLSQGGESSHDHIAHSEAARLRFRHFRYEEA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 SGPHEALAHLRALCCQWLQPEAHSKEQILELLVLEQFLGALPPEIQAWVGAQSPKSGEEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SGPHEALAHLRALCCQWLQPEAHSKEQILELLVLEQFLGALPPEIQAWVGAQSPKSGEEA 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 AVLVEDLTQVLDKRGWDPGAEPTEASCKQSDLGESEPSNVTETLMGGVSLGPAFVKACEP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AVLVEDLTQVLDKRGWDPGAEPTEASCKQSDLGESEPSNVTETLMGGVSLGPAFVKACEP 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 EGSSERSGLSGEIWTKSVTQQIHFKKTSGPYKDVPTDQRGRESGASRNSSSAWPNLTSQE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EGSSERSGLSGEIWTKSVTQQIHFKKTSGPYKDVPTDQRGRESGASRNSSSAWPNLTSQE 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 KPPSEDKFDLVDAYGTEPPYTYSGKRSSKCRECRKMFQSASALEAHQKTHSRKTPYACSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KPPSEDKFDLVDAYGTEPPYTYSGKRSSKCRECRKMFQSASALEAHQKTHSRKTPYACSE 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 CGKAFSRSTHLAQHQVVHTGAKPHECKECGKAFSRVTHLTQHQRIHTGEKPYKCGECGKT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 CGKAFSRSTHLAQHQVVHTGAKPHECKECGKAFSRVTHLTQHQRIHTGEKPYKCGECGKT 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB8 FSRSTHLTQHQRVHTGERPYECDACGKAFSQSTHLTQHQRIHTGEKPYKCDACGRAFSDC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FSRSTHLTQHQRVHTGERPYECDACGKAFSQSTHLTQHQRIHTGEKPYKCDACGRAFSDC 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB8 SALIRHLRIHSGEKPYQCKVCPKAFAQSSSLIEHQRIHTGEKPYKCSDCGKAFSRSSALM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SALIRHLRIHSGEKPYQCKVCPKAFAQSSSLIEHQRIHTGEKPYKCSDCGKAFSRSSALM 430 440 450 460 470 480 490 pF1KB8 VHLRIHITVLQ ::::::::::: XP_011 VHLRIHITVLQ 490 >>NP_862829 (OMIM: 165260) zinc finger and SCAN domain-c (491 aa) initn: 3401 init1: 3401 opt: 3401 Z-score: 2363.6 bits: 446.8 E(85289): 6.5e-125 Smith-Waterman score: 3401; 100.0% identity (100.0% similar) in 491 aa overlap (1-491:1-491) 10 20 30 40 50 60 pF1KB8 MAIPKHSLSPVPWEEDSFLQVKVEEEEEASLSQGGESSHDHIAHSEAARLRFRHFRYEEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_862 MAIPKHSLSPVPWEEDSFLQVKVEEEEEASLSQGGESSHDHIAHSEAARLRFRHFRYEEA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 SGPHEALAHLRALCCQWLQPEAHSKEQILELLVLEQFLGALPPEIQAWVGAQSPKSGEEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_862 SGPHEALAHLRALCCQWLQPEAHSKEQILELLVLEQFLGALPPEIQAWVGAQSPKSGEEA 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 AVLVEDLTQVLDKRGWDPGAEPTEASCKQSDLGESEPSNVTETLMGGVSLGPAFVKACEP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_862 AVLVEDLTQVLDKRGWDPGAEPTEASCKQSDLGESEPSNVTETLMGGVSLGPAFVKACEP 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 EGSSERSGLSGEIWTKSVTQQIHFKKTSGPYKDVPTDQRGRESGASRNSSSAWPNLTSQE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_862 EGSSERSGLSGEIWTKSVTQQIHFKKTSGPYKDVPTDQRGRESGASRNSSSAWPNLTSQE 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 KPPSEDKFDLVDAYGTEPPYTYSGKRSSKCRECRKMFQSASALEAHQKTHSRKTPYACSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_862 KPPSEDKFDLVDAYGTEPPYTYSGKRSSKCRECRKMFQSASALEAHQKTHSRKTPYACSE 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 CGKAFSRSTHLAQHQVVHTGAKPHECKECGKAFSRVTHLTQHQRIHTGEKPYKCGECGKT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_862 CGKAFSRSTHLAQHQVVHTGAKPHECKECGKAFSRVTHLTQHQRIHTGEKPYKCGECGKT 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB8 FSRSTHLTQHQRVHTGERPYECDACGKAFSQSTHLTQHQRIHTGEKPYKCDACGRAFSDC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_862 FSRSTHLTQHQRVHTGERPYECDACGKAFSQSTHLTQHQRIHTGEKPYKCDACGRAFSDC 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB8 SALIRHLRIHSGEKPYQCKVCPKAFAQSSSLIEHQRIHTGEKPYKCSDCGKAFSRSSALM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_862 SALIRHLRIHSGEKPYQCKVCPKAFAQSSSLIEHQRIHTGEKPYKCSDCGKAFSRSSALM 430 440 450 460 470 480 490 pF1KB8 VHLRIHITVLQ ::::::::::: NP_862 VHLRIHITVLQ 490 >>XP_006723255 (OMIM: 165260) PREDICTED: zinc finger and (491 aa) initn: 3401 init1: 3401 opt: 3401 Z-score: 2363.6 bits: 446.8 E(85289): 6.5e-125 Smith-Waterman score: 3401; 100.0% identity (100.0% similar) in 491 aa overlap (1-491:1-491) 10 20 30 40 50 60 pF1KB8 MAIPKHSLSPVPWEEDSFLQVKVEEEEEASLSQGGESSHDHIAHSEAARLRFRHFRYEEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 MAIPKHSLSPVPWEEDSFLQVKVEEEEEASLSQGGESSHDHIAHSEAARLRFRHFRYEEA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 SGPHEALAHLRALCCQWLQPEAHSKEQILELLVLEQFLGALPPEIQAWVGAQSPKSGEEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 SGPHEALAHLRALCCQWLQPEAHSKEQILELLVLEQFLGALPPEIQAWVGAQSPKSGEEA 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 AVLVEDLTQVLDKRGWDPGAEPTEASCKQSDLGESEPSNVTETLMGGVSLGPAFVKACEP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 AVLVEDLTQVLDKRGWDPGAEPTEASCKQSDLGESEPSNVTETLMGGVSLGPAFVKACEP 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 EGSSERSGLSGEIWTKSVTQQIHFKKTSGPYKDVPTDQRGRESGASRNSSSAWPNLTSQE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 EGSSERSGLSGEIWTKSVTQQIHFKKTSGPYKDVPTDQRGRESGASRNSSSAWPNLTSQE 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 KPPSEDKFDLVDAYGTEPPYTYSGKRSSKCRECRKMFQSASALEAHQKTHSRKTPYACSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 KPPSEDKFDLVDAYGTEPPYTYSGKRSSKCRECRKMFQSASALEAHQKTHSRKTPYACSE 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 CGKAFSRSTHLAQHQVVHTGAKPHECKECGKAFSRVTHLTQHQRIHTGEKPYKCGECGKT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 CGKAFSRSTHLAQHQVVHTGAKPHECKECGKAFSRVTHLTQHQRIHTGEKPYKCGECGKT 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB8 FSRSTHLTQHQRVHTGERPYECDACGKAFSQSTHLTQHQRIHTGEKPYKCDACGRAFSDC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 FSRSTHLTQHQRVHTGERPYECDACGKAFSQSTHLTQHQRIHTGEKPYKCDACGRAFSDC 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB8 SALIRHLRIHSGEKPYQCKVCPKAFAQSSSLIEHQRIHTGEKPYKCSDCGKAFSRSSALM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 SALIRHLRIHSGEKPYQCKVCPKAFAQSSSLIEHQRIHTGEKPYKCSDCGKAFSRSSALM 430 440 450 460 470 480 490 pF1KB8 VHLRIHITVLQ ::::::::::: XP_006 VHLRIHITVLQ 490 >>XP_016882236 (OMIM: 165260) PREDICTED: zinc finger and (327 aa) initn: 2295 init1: 2295 opt: 2295 Z-score: 1603.9 bits: 305.7 E(85289): 1.3e-82 Smith-Waterman score: 2295; 100.0% identity (100.0% similar) in 327 aa overlap (165-491:1-327) 140 150 160 170 180 190 pF1KB8 GWDPGAEPTEASCKQSDLGESEPSNVTETLMGGVSLGPAFVKACEPEGSSERSGLSGEIW :::::::::::::::::::::::::::::: XP_016 MGGVSLGPAFVKACEPEGSSERSGLSGEIW 10 20 30 200 210 220 230 240 250 pF1KB8 TKSVTQQIHFKKTSGPYKDVPTDQRGRESGASRNSSSAWPNLTSQEKPPSEDKFDLVDAY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TKSVTQQIHFKKTSGPYKDVPTDQRGRESGASRNSSSAWPNLTSQEKPPSEDKFDLVDAY 40 50 60 70 80 90 260 270 280 290 300 310 pF1KB8 GTEPPYTYSGKRSSKCRECRKMFQSASALEAHQKTHSRKTPYACSECGKAFSRSTHLAQH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GTEPPYTYSGKRSSKCRECRKMFQSASALEAHQKTHSRKTPYACSECGKAFSRSTHLAQH 100 110 120 130 140 150 320 330 340 350 360 370 pF1KB8 QVVHTGAKPHECKECGKAFSRVTHLTQHQRIHTGEKPYKCGECGKTFSRSTHLTQHQRVH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QVVHTGAKPHECKECGKAFSRVTHLTQHQRIHTGEKPYKCGECGKTFSRSTHLTQHQRVH 160 170 180 190 200 210 380 390 400 410 420 430 pF1KB8 TGERPYECDACGKAFSQSTHLTQHQRIHTGEKPYKCDACGRAFSDCSALIRHLRIHSGEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TGERPYECDACGKAFSQSTHLTQHQRIHTGEKPYKCDACGRAFSDCSALIRHLRIHSGEK 220 230 240 250 260 270 440 450 460 470 480 490 pF1KB8 PYQCKVCPKAFAQSSSLIEHQRIHTGEKPYKCSDCGKAFSRSSALMVHLRIHITVLQ ::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PYQCKVCPKAFAQSSSLIEHQRIHTGEKPYKCSDCGKAFSRSSALMVHLRIHITVLQ 280 290 300 310 320 >>XP_011525220 (OMIM: 165260) PREDICTED: zinc finger and (327 aa) initn: 2295 init1: 2295 opt: 2295 Z-score: 1603.9 bits: 305.7 E(85289): 1.3e-82 Smith-Waterman score: 2295; 100.0% identity (100.0% similar) in 327 aa overlap (165-491:1-327) 140 150 160 170 180 190 pF1KB8 GWDPGAEPTEASCKQSDLGESEPSNVTETLMGGVSLGPAFVKACEPEGSSERSGLSGEIW :::::::::::::::::::::::::::::: XP_011 MGGVSLGPAFVKACEPEGSSERSGLSGEIW 10 20 30 200 210 220 230 240 250 pF1KB8 TKSVTQQIHFKKTSGPYKDVPTDQRGRESGASRNSSSAWPNLTSQEKPPSEDKFDLVDAY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TKSVTQQIHFKKTSGPYKDVPTDQRGRESGASRNSSSAWPNLTSQEKPPSEDKFDLVDAY 40 50 60 70 80 90 260 270 280 290 300 310 pF1KB8 GTEPPYTYSGKRSSKCRECRKMFQSASALEAHQKTHSRKTPYACSECGKAFSRSTHLAQH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GTEPPYTYSGKRSSKCRECRKMFQSASALEAHQKTHSRKTPYACSECGKAFSRSTHLAQH 100 110 120 130 140 150 320 330 340 350 360 370 pF1KB8 QVVHTGAKPHECKECGKAFSRVTHLTQHQRIHTGEKPYKCGECGKTFSRSTHLTQHQRVH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QVVHTGAKPHECKECGKAFSRVTHLTQHQRIHTGEKPYKCGECGKTFSRSTHLTQHQRVH 160 170 180 190 200 210 380 390 400 410 420 430 pF1KB8 TGERPYECDACGKAFSQSTHLTQHQRIHTGEKPYKCDACGRAFSDCSALIRHLRIHSGEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TGERPYECDACGKAFSQSTHLTQHQRIHTGEKPYKCDACGRAFSDCSALIRHLRIHSGEK 220 230 240 250 260 270 440 450 460 470 480 490 pF1KB8 PYQCKVCPKAFAQSSSLIEHQRIHTGEKPYKCSDCGKAFSRSSALMVHLRIHITVLQ ::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PYQCKVCPKAFAQSSSLIEHQRIHTGEKPYKCSDCGKAFSRSSALMVHLRIHITVLQ 280 290 300 310 320 >>XP_011540503 (OMIM: 611703) PREDICTED: zinc finger pro (452 aa) initn: 1105 init1: 1105 opt: 1105 Z-score: 782.6 bits: 154.2 E(85289): 7.5e-37 Smith-Waterman score: 1108; 51.2% identity (74.4% similar) in 297 aa overlap (196-486:49-338) 170 180 190 200 210 220 pF1KB8 GGVSLGPAFVKACEPEGSSERSGLSGEIWTKSVTQQIHFKKTSG-PYKDV---PTDQRGR . ......: :: : ... : ...: XP_011 DLYRDVMQENYGNVVSLDFEIRSENEVNPKQEISEDVQFGTTSERPAENAEENPESEEGF 20 30 40 50 60 70 230 240 250 260 270 pF1KB8 ESGASRNSSSAWPNLTSQE--KPPSEDKFDLVDAYGTEPPYTYSGKRSSKCRECRKMFQS ::: : : .::..: . : . ::. ...: : : .: : :.. XP_011 ESGDR--SERQWGDLTAEEWVSYPLQPVTDLL-----VHKEVHTGIRYHICSHCGKAFSQ 80 90 100 110 120 130 280 290 300 310 320 330 pF1KB8 ASALEAHQKTHSRKTPYACSECGKAFSRSTHLAQHQVVHTGAKPHECKECGKAFSRVTHL : :. :::::. :: : ::::.::::.:: ::: .::: .:..:.::::.:.: .:: XP_011 ISDLNRHQKTHTGDRPYKCYECGKGFSRSSHLIQHQRTHTGERPYDCNECGKSFGRSSHL 140 150 160 170 180 190 340 350 360 370 380 390 pF1KB8 TQHQRIHTGEKPYKCGECGKTFSRSTHLTQHQRVHTGERPYECDACGKAFSQSTHLTQHQ ::: :::::::.::.::::.: : .:: ::::.:.::.::::. :::.::.:.::.::: XP_011 IQHQTIHTGEKPHKCNECGKSFCRLSHLIQHQRTHSGEKPYECEECGKSFSRSSHLAQHQ 200 210 220 230 240 250 400 410 420 430 440 450 pF1KB8 RIHTGEKPYKCDACGRAFSDCSALIRHLRIHSGEKPYQCKVCPKAFAQSSSLIEHQRIHT : :::::::.:. :::.::. : ::.: :.:.::.::.: : : :.:.:.:..:.: :: XP_011 RTHTGEKPYECNECGRGFSERSDLIKHYRVHTGERPYKCDECGKNFSQNSDLVRHRRAHT 260 270 280 290 300 310 460 470 480 490 pF1KB8 GEKPYKCSDCGKAFSRSSALMVHLRIHITVLQ :::::.:..::. ::: : :. : : : XP_011 GEKPYHCNECGENFSRISHLVQHQRTHTGEKPYECNACGKSFSRSSHLITHQKIHTGEKP 320 330 340 350 360 370 >-- initn: 1185 init1: 569 opt: 569 Z-score: 413.4 bits: 85.8 E(85289): 2.7e-16 Smith-Waterman score: 569; 65.2% identity (86.6% similar) in 112 aa overlap (375-486:339-450) 350 360 370 380 390 400 pF1KB8 IHTGEKPYKCGECGKTFSRSTHLTQHQRVHTGERPYECDACGKAFSQSTHLTQHQRIHTG :::.::::.::::.::.:.:: ::.:::: XP_011 AHTGEKPYHCNECGENFSRISHLVQHQRTHTGEKPYECNACGKSFSRSSHLITHQKIHTG 310 320 330 340 350 360 410 420 430 440 450 460 pF1KB8 EKPYKCDACGRAFSDCSALIRHLRIHSGEKPYQCKVCPKAFAQSSSLIEHQRIHTGEKPY ::::.:. : :.:.. : ::.: : :.:::::.: : :.:.:::.:: :::.::::::: XP_011 EKPYECNECWRSFGERSDLIKHQRTHTGEKPYECVQCGKGFTQSSNLITHQRVHTGEKPY 370 380 390 400 410 420 470 480 490 pF1KB8 KCSDCGKAFSRSSALMVHLRIHITVLQ .:..: :.:::::::. : :.: XP_011 ECTECEKSFSRSSALIKHKRVHTD 430 440 450 >>NP_085137 (OMIM: 611703) zinc finger protein 436 [Homo (470 aa) initn: 1105 init1: 1105 opt: 1105 Z-score: 782.4 bits: 154.2 E(85289): 7.7e-37 Smith-Waterman score: 1120; 46.0% identity (69.6% similar) in 378 aa overlap (116-486:8-356) 90 100 110 120 130 140 pF1KB8 EQILELLVLEQFLGALPPEIQAWVGAQSPKSGEEAAVLVEDLTQVLDKRGWDPGAEPTEA .: .: : ::... : .. : .: .: NP_085 MAATLLMAGSQAPVTFEDMAMYLTREEW----RPLDA 10 20 30 150 160 170 180 190 200 pF1KB8 SCKQSDLGESEPSNVTETLMGGVSLGPAFVKACEPEGSSERSGLSGEIWTKS-VTQQIHF . : :: . .: . .:.: . . : :: .:. :. ......: NP_085 A--QRDLYR----DVMQENYGNVV-------SLDFEIRSE-----NEVNPKQEISEDVQF 40 50 60 70 210 220 230 240 250 pF1KB8 KKTSG-PYKDV---PTDQRGRESGASRNSSSAWPNLTSQE--KPPSEDKFDLVDAYGTEP :: : ... : ...: ::: .: : : .::..: . : . ::. : NP_085 GTTSERPAENAEENPESEEGFESG-DR-SERQWGDLTAEEWVSYPLQPVTDLL--VHKE- 80 90 100 110 120 130 260 270 280 290 300 310 pF1KB8 PYTYSGKRSSKCRECRKMFQSASALEAHQKTHSRKTPYACSECGKAFSRSTHLAQHQVVH ...: : : .: : :.. : :. :::::. :: : ::::.::::.:: ::: .: NP_085 --VHTGIRYHICSHCGKAFSQISDLNRHQKTHTGDRPYKCYECGKGFSRSSHLIQHQRTH 140 150 160 170 180 320 330 340 350 360 370 pF1KB8 TGAKPHECKECGKAFSRVTHLTQHQRIHTGEKPYKCGECGKTFSRSTHLTQHQRVHTGER :: .:..:.::::.:.: .:: ::: :::::::.::.::::.: : .:: ::::.:.::. NP_085 TGERPYDCNECGKSFGRSSHLIQHQTIHTGEKPHKCNECGKSFCRLSHLIQHQRTHSGEK 190 200 210 220 230 240 380 390 400 410 420 430 pF1KB8 PYECDACGKAFSQSTHLTQHQRIHTGEKPYKCDACGRAFSDCSALIRHLRIHSGEKPYQC ::::. :::.::.:.::.:::: :::::::.:. :::.::. : ::.: :.:.::.::.: NP_085 PYECEECGKSFSRSSHLAQHQRTHTGEKPYECNECGRGFSERSDLIKHYRVHTGERPYKC 250 260 270 280 290 300 440 450 460 470 480 490 pF1KB8 KVCPKAFAQSSSLIEHQRIHTGEKPYKCSDCGKAFSRSSALMVHLRIHITVLQ : : :.:.:.:..:.: :::::::.:..::. ::: : :. : : : NP_085 DECGKNFSQNSDLVRHRRAHTGEKPYHCNECGENFSRISHLVQHQRTHTGEKPYECNACG 310 320 330 340 350 360 NP_085 KSFSRSSHLITHQKIHTGEKPYECNECWRSFGERSDLIKHQRTHTGEKPYECVQCGKGFT 370 380 390 400 410 420 >-- initn: 1185 init1: 569 opt: 569 Z-score: 413.2 bits: 85.9 E(85289): 2.8e-16 Smith-Waterman score: 569; 65.2% identity (86.6% similar) in 112 aa overlap (375-486:357-468) 350 360 370 380 390 400 pF1KB8 IHTGEKPYKCGECGKTFSRSTHLTQHQRVHTGERPYECDACGKAFSQSTHLTQHQRIHTG :::.::::.::::.::.:.:: ::.:::: NP_085 AHTGEKPYHCNECGENFSRISHLVQHQRTHTGEKPYECNACGKSFSRSSHLITHQKIHTG 330 340 350 360 370 380 410 420 430 440 450 460 pF1KB8 EKPYKCDACGRAFSDCSALIRHLRIHSGEKPYQCKVCPKAFAQSSSLIEHQRIHTGEKPY ::::.:. : :.:.. : ::.: : :.:::::.: : :.:.:::.:: :::.::::::: NP_085 EKPYECNECWRSFGERSDLIKHQRTHTGEKPYECVQCGKGFTQSSNLITHQRVHTGEKPY 390 400 410 420 430 440 470 480 490 pF1KB8 KCSDCGKAFSRSSALMVHLRIHITVLQ .:..: :.:::::::. : :.: NP_085 ECTECEKSFSRSSALIKHKRVHTD 450 460 470 >>NP_001070663 (OMIM: 611703) zinc finger protein 436 [H (470 aa) initn: 1105 init1: 1105 opt: 1105 Z-score: 782.4 bits: 154.2 E(85289): 7.7e-37 Smith-Waterman score: 1120; 46.0% identity (69.6% similar) in 378 aa overlap (116-486:8-356) 90 100 110 120 130 140 pF1KB8 EQILELLVLEQFLGALPPEIQAWVGAQSPKSGEEAAVLVEDLTQVLDKRGWDPGAEPTEA .: .: : ::... : .. : .: .: NP_001 MAATLLMAGSQAPVTFEDMAMYLTREEW----RPLDA 10 20 30 150 160 170 180 190 200 pF1KB8 SCKQSDLGESEPSNVTETLMGGVSLGPAFVKACEPEGSSERSGLSGEIWTKS-VTQQIHF . : :: . .: . .:.: . . : :: .:. :. ......: NP_001 A--QRDLYR----DVMQENYGNVV-------SLDFEIRSE-----NEVNPKQEISEDVQF 40 50 60 70 210 220 230 240 250 pF1KB8 KKTSG-PYKDV---PTDQRGRESGASRNSSSAWPNLTSQE--KPPSEDKFDLVDAYGTEP :: : ... : ...: ::: .: : : .::..: . : . ::. : NP_001 GTTSERPAENAEENPESEEGFESG-DR-SERQWGDLTAEEWVSYPLQPVTDLL--VHKE- 80 90 100 110 120 130 260 270 280 290 300 310 pF1KB8 PYTYSGKRSSKCRECRKMFQSASALEAHQKTHSRKTPYACSECGKAFSRSTHLAQHQVVH ...: : : .: : :.. : :. :::::. :: : ::::.::::.:: ::: .: NP_001 --VHTGIRYHICSHCGKAFSQISDLNRHQKTHTGDRPYKCYECGKGFSRSSHLIQHQRTH 140 150 160 170 180 320 330 340 350 360 370 pF1KB8 TGAKPHECKECGKAFSRVTHLTQHQRIHTGEKPYKCGECGKTFSRSTHLTQHQRVHTGER :: .:..:.::::.:.: .:: ::: :::::::.::.::::.: : .:: ::::.:.::. NP_001 TGERPYDCNECGKSFGRSSHLIQHQTIHTGEKPHKCNECGKSFCRLSHLIQHQRTHSGEK 190 200 210 220 230 240 380 390 400 410 420 430 pF1KB8 PYECDACGKAFSQSTHLTQHQRIHTGEKPYKCDACGRAFSDCSALIRHLRIHSGEKPYQC ::::. :::.::.:.::.:::: :::::::.:. :::.::. : ::.: :.:.::.::.: NP_001 PYECEECGKSFSRSSHLAQHQRTHTGEKPYECNECGRGFSERSDLIKHYRVHTGERPYKC 250 260 270 280 290 300 440 450 460 470 480 490 pF1KB8 KVCPKAFAQSSSLIEHQRIHTGEKPYKCSDCGKAFSRSSALMVHLRIHITVLQ : : :.:.:.:..:.: :::::::.:..::. ::: : :. : : : NP_001 DECGKNFSQNSDLVRHRRAHTGEKPYHCNECGENFSRISHLVQHQRTHTGEKPYECNACG 310 320 330 340 350 360 NP_001 KSFSRSSHLITHQKIHTGEKPYECNECWRSFGERSDLIKHQRTHTGEKPYECVQCGKGFT 370 380 390 400 410 420 >-- initn: 1185 init1: 569 opt: 569 Z-score: 413.2 bits: 85.9 E(85289): 2.8e-16 Smith-Waterman score: 569; 65.2% identity (86.6% similar) in 112 aa overlap (375-486:357-468) 350 360 370 380 390 400 pF1KB8 IHTGEKPYKCGECGKTFSRSTHLTQHQRVHTGERPYECDACGKAFSQSTHLTQHQRIHTG :::.::::.::::.::.:.:: ::.:::: NP_001 AHTGEKPYHCNECGENFSRISHLVQHQRTHTGEKPYECNACGKSFSRSSHLITHQKIHTG 330 340 350 360 370 380 410 420 430 440 450 460 pF1KB8 EKPYKCDACGRAFSDCSALIRHLRIHSGEKPYQCKVCPKAFAQSSSLIEHQRIHTGEKPY ::::.:. : :.:.. : ::.: : :.:::::.: : :.:.:::.:: :::.::::::: NP_001 EKPYECNECWRSFGERSDLIKHQRTHTGEKPYECVQCGKGFTQSSNLITHQRVHTGEKPY 390 400 410 420 430 440 470 480 490 pF1KB8 KCSDCGKAFSRSSALMVHLRIHITVLQ .:..: :.:::::::. : :.: NP_001 ECTECEKSFSRSSALIKHKRVHTD 450 460 470 >>NP_001276331 (OMIM: 604077) zinc finger protein 135 is (616 aa) initn: 2076 init1: 1100 opt: 1104 Z-score: 780.3 bits: 154.2 E(85289): 1e-36 Smith-Waterman score: 1104; 54.5% identity (74.3% similar) in 292 aa overlap (198-486:240-530) 170 180 190 200 210 220 pF1KB8 VSLGPAFVKACEPEGSSERSGLSGEIWTKSVTQQIHFKKTSGPYKDVPTDQRGRESGASR .. :. ..: : .. :. : . : NP_001 RNSSALTKHQRIHTGEKPYKCTQCGRTFNQIAPLIQHQRTHTGEKPYECSECGK-SFSFR 210 220 230 240 250 260 230 240 250 260 270 280 pF1KB8 NSSSAWPNLTSQEKPP--SE-DKFDLVDAYGTEPPYTYSGKRSSKCRECRKMFQSASALE .: : . ::: :: : . . :. ..:.. .: :: : :. .:.: NP_001 SSFSQHERTHTGEKPYECSECGKAFRQSIHLTQHLRIHTGEKPYQCGECGKAFSHSSSLT 270 280 290 300 310 320 290 300 310 320 330 340 pF1KB8 AHQKTHSRKTPYACSECGKAFSRSTHLAQHQVVHTGAKPHECKECGKAFSRVTHLTQHQR ::. :. . :: : ::::::.. : : ::: .::: ::.:: :::::::. : ::.:.: NP_001 KHQRIHTGEKPYECHECGKAFTQITPLIQHQRTHTGEKPYECGECGKAFSQSTLLTEHRR 330 340 350 360 370 380 350 360 370 380 390 400 pF1KB8 IHTGEKPYKCGECGKTFSRSTHLTQHQRVHTGERPYECDACGKAFSQSTHLTQHQRIHTG :::::::: :.:::::::.:. :.::.:.::::.::::. ::::: :::::::::::::: NP_001 IHTGEKPYGCNECGKTFSHSSSLSQHERTHTGEKPYECSQCGKAFRQSTHLTQHQRIHTG 390 400 410 420 430 440 410 420 430 440 450 460 pF1KB8 EKPYKCDACGRAFSDCSALIRHLRIHSGEKPYQCKVCPKAFAQSSSLIEHQRIHTGEKPY ::::.:. ::.::: :.: .: :::.:::::.:. : .::.: . ::.::::::::::: NP_001 EKPYECNDCGKAFSHSSSLTKHQRIHTGEKPYECNQCGRAFSQLAPLIQHQRIHTGEKPY 450 460 470 480 490 500 470 480 490 pF1KB8 KCSDCGKAFSRSSALMVHLRIHITVLQ .:..::.:::.:: :. : ::: NP_001 ECNQCGRAFSQSSLLIEHQRIHTKEKPYGCNECGKSFSHSSSLSQHERTHTGEKPYECHD 510 520 530 540 550 560 >-- initn: 441 init1: 441 opt: 444 Z-score: 325.8 bits: 70.1 E(85289): 2.1e-11 Smith-Waterman score: 444; 66.3% identity (83.7% similar) in 86 aa overlap (347-432:531-616) 320 330 340 350 360 370 pF1KB8 VHTGAKPHECKECGKAFSRVTHLTQHQRIHTGEKPYKCGECGKTFSRSTHLTQHQRVHTG : :::: :.::::.::.:. :.::.:.::: NP_001 IHTGEKPYECNQCGRAFSQSSLLIEHQRIHTKEKPYGCNECGKSFSHSSSLSQHERTHTG 510 520 530 540 550 560 380 390 400 410 420 430 pF1KB8 ERPYECDACGKAFSQSTHLTQHQRIHTGEKPYKCDACGRAFSDCSALIRHLRIHSGEKPY :.:::: :::.: ::::::::.::::::::: : ::.::. :.: .: : :.: NP_001 EKPYECHDCGKSFRQSTHLTQHRRIHTGEKPYACRDCGKAFTHSSSLTKHQRTHTG 570 580 590 600 610 440 450 460 470 480 490 pF1KB8 QCKVCPKAFAQSSSLIEHQRIHTGEKPYKCSDCGKAFSRSSALMVHLRIHITVLQ >-- initn: 1011 init1: 368 opt: 380 Z-score: 281.7 bits: 61.9 E(85289): 6e-09 Smith-Waterman score: 380; 48.7% identity (69.2% similar) in 117 aa overlap (302-418:124-238) 280 290 300 310 320 330 pF1KB8 ECRKMFQSASALEAHQKTHSRKTPYACSECGKAFSRSTHLAQHQVVHTGAKPHECKECGK :. .: . : .. .. .:: :: NP_001 SCESLESLAVPVAFTPVKTPVLEQWQRNGFGENISLNPDLPHQPMTPERQSPHTWGTRGK 100 110 120 130 140 150 340 350 360 370 380 390 pF1KB8 AFSRVTHLTQHQRIHTGEKPYKCGECGKTFSRSTHLTQHQRVHTGERPYECDACGKAFSQ . :. :. . :::::: ::::.::.:. : .:.:.::::::::: : :.: . NP_001 --REKPDLNVLQKTCVKEKPYKCQECGKAFSHSSALIEHHRTHTGERPYECHECLKGFRN 160 170 180 190 200 210 400 410 420 430 440 450 pF1KB8 STHLTQHQRIHTGEKPYKCDACGRAFSDCSALIRHLRIHSGEKPYQCKVCPKAFAQSSSL :. ::.::::::::::::: :::.:. NP_001 SSALTKHQRIHTGEKPYKCTQCGRTFNQIAPLIQHQRTHTGEKPYECSECGKSFSFRSSF 220 230 240 250 260 270 491 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 02:09:46 2016 done: Sat Nov 5 02:09:47 2016 Total Scan time: 8.170 Total Display time: 0.090 Function used was FASTA [36.3.4 Apr, 2011]