FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB8339, 310 aa 1>>>pF1KB8339 310 - 310 aa - 310 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.9909+/-0.000352; mu= 9.1477+/- 0.022 mean_var=131.0134+/-26.224, 0's: 0 Z-trim(117.8): 134 B-trim: 0 in 0/53 Lambda= 0.112051 statistics sampled from 29958 (30110) to 29958 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.722), E-opt: 0.2 (0.353), width: 16 Scan time: 5.710 The best scores are: opt bits E(85289) NP_009053 (OMIM: 191523,602491) upstream stimulato ( 310) 2006 335.2 1e-91 NP_001263302 (OMIM: 191523,602491) upstream stimul ( 310) 2006 335.2 1e-91 NP_996888 (OMIM: 191523,602491) upstream stimulato ( 251) 1634 275.0 1.1e-73 NP_997174 (OMIM: 600390) upstream stimulatory fact ( 279) 756 133.1 6.3e-31 NP_003358 (OMIM: 600390) upstream stimulatory fact ( 346) 756 133.2 7.5e-31 NP_001308079 (OMIM: 600390) upstream stimulatory f ( 215) 681 120.9 2.3e-27 XP_016882688 (OMIM: 600390) PREDICTED: upstream st ( 284) 662 117.9 2.4e-26 XP_005259254 (OMIM: 600390) PREDICTED: upstream st ( 351) 662 118.0 2.8e-26 XP_011525563 (OMIM: 600390) PREDICTED: upstream st ( 244) 283 56.6 5.9e-08 XP_011525562 (OMIM: 600390) PREDICTED: upstream st ( 258) 281 56.3 7.7e-08 NP_002373 (OMIM: 154950,171300) protein max isofor ( 160) 195 42.2 0.00081 NP_660088 (OMIM: 154950,171300) protein max isofor ( 103) 188 41.0 0.0013 XP_016884411 (OMIM: 600481) PREDICTED: sterol regu ( 749) 199 43.4 0.0017 NP_660087 (OMIM: 154950,171300) protein max isofor ( 151) 187 40.9 0.0019 XP_016884410 (OMIM: 600481) PREDICTED: sterol regu ( 965) 199 43.4 0.0021 XP_011535075 (OMIM: 154950,171300) PREDICTED: prot ( 153) 186 40.8 0.0022 XP_011528649 (OMIM: 600481) PREDICTED: sterol regu (1016) 199 43.5 0.0022 XP_006724373 (OMIM: 600481) PREDICTED: sterol regu (1111) 199 43.5 0.0024 NP_004590 (OMIM: 600481) sterol regulatory element (1141) 199 43.5 0.0024 >>NP_009053 (OMIM: 191523,602491) upstream stimulatory f (310 aa) initn: 2006 init1: 2006 opt: 2006 Z-score: 1767.6 bits: 335.2 E(85289): 1e-91 Smith-Waterman score: 2006; 100.0% identity (100.0% similar) in 310 aa overlap (1-310:1-310) 10 20 30 40 50 60 pF1KB8 MKGQQKTAETEEGTVQIQEGAVATGEDPTSVAIASIQSAATFPDPNVKYVFRTENGGQVM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_009 MKGQQKTAETEEGTVQIQEGAVATGEDPTSVAIASIQSAATFPDPNVKYVFRTENGGQVM 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 YRVIQVSEGQLDGQTEGTGAISGYPATQSMTQAVIQGAFTSDDAVDTEGTAAETHYTYFP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_009 YRVIQVSEGQLDGQTEGTGAISGYPATQSMTQAVIQGAFTSDDAVDTEGTAAETHYTYFP 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 STAVGDGAGGTTSGSTAAVVTTQGSEALLGQATPPGTGQFFVMMSPQEVLQGGSQRSIAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_009 STAVGDGAGGTTSGSTAAVVTTQGSEALLGQATPPGTGQFFVMMSPQEVLQGGSQRSIAP 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 RTHPYSPKSEAPRTTRDEKRRAQHNEVERRRRDKINNWIVQLSKIIPDCSMESTKSGQSK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_009 RTHPYSPKSEAPRTTRDEKRRAQHNEVERRRRDKINNWIVQLSKIIPDCSMESTKSGQSK 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 GGILSKACDYIQELRQSNHRLSEELQGLDQLQLDNDVLRQQVEDLKNKNLLLRAQLRHHG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_009 GGILSKACDYIQELRQSNHRLSEELQGLDQLQLDNDVLRQQVEDLKNKNLLLRAQLRHHG 250 260 270 280 290 300 310 pF1KB8 LEVVIKNDSN :::::::::: NP_009 LEVVIKNDSN 310 >>NP_001263302 (OMIM: 191523,602491) upstream stimulator (310 aa) initn: 2006 init1: 2006 opt: 2006 Z-score: 1767.6 bits: 335.2 E(85289): 1e-91 Smith-Waterman score: 2006; 100.0% identity (100.0% similar) in 310 aa overlap (1-310:1-310) 10 20 30 40 50 60 pF1KB8 MKGQQKTAETEEGTVQIQEGAVATGEDPTSVAIASIQSAATFPDPNVKYVFRTENGGQVM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MKGQQKTAETEEGTVQIQEGAVATGEDPTSVAIASIQSAATFPDPNVKYVFRTENGGQVM 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 YRVIQVSEGQLDGQTEGTGAISGYPATQSMTQAVIQGAFTSDDAVDTEGTAAETHYTYFP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YRVIQVSEGQLDGQTEGTGAISGYPATQSMTQAVIQGAFTSDDAVDTEGTAAETHYTYFP 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 STAVGDGAGGTTSGSTAAVVTTQGSEALLGQATPPGTGQFFVMMSPQEVLQGGSQRSIAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 STAVGDGAGGTTSGSTAAVVTTQGSEALLGQATPPGTGQFFVMMSPQEVLQGGSQRSIAP 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 RTHPYSPKSEAPRTTRDEKRRAQHNEVERRRRDKINNWIVQLSKIIPDCSMESTKSGQSK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RTHPYSPKSEAPRTTRDEKRRAQHNEVERRRRDKINNWIVQLSKIIPDCSMESTKSGQSK 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 GGILSKACDYIQELRQSNHRLSEELQGLDQLQLDNDVLRQQVEDLKNKNLLLRAQLRHHG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GGILSKACDYIQELRQSNHRLSEELQGLDQLQLDNDVLRQQVEDLKNKNLLLRAQLRHHG 250 260 270 280 290 300 310 pF1KB8 LEVVIKNDSN :::::::::: NP_001 LEVVIKNDSN 310 >>NP_996888 (OMIM: 191523,602491) upstream stimulatory f (251 aa) initn: 1634 init1: 1634 opt: 1634 Z-score: 1443.9 bits: 275.0 E(85289): 1.1e-73 Smith-Waterman score: 1634; 100.0% identity (100.0% similar) in 251 aa overlap (60-310:1-251) 30 40 50 60 70 80 pF1KB8 SVAIASIQSAATFPDPNVKYVFRTENGGQVMYRVIQVSEGQLDGQTEGTGAISGYPATQS :::::::::::::::::::::::::::::: NP_996 MYRVIQVSEGQLDGQTEGTGAISGYPATQS 10 20 30 90 100 110 120 130 140 pF1KB8 MTQAVIQGAFTSDDAVDTEGTAAETHYTYFPSTAVGDGAGGTTSGSTAAVVTTQGSEALL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_996 MTQAVIQGAFTSDDAVDTEGTAAETHYTYFPSTAVGDGAGGTTSGSTAAVVTTQGSEALL 40 50 60 70 80 90 150 160 170 180 190 200 pF1KB8 GQATPPGTGQFFVMMSPQEVLQGGSQRSIAPRTHPYSPKSEAPRTTRDEKRRAQHNEVER :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_996 GQATPPGTGQFFVMMSPQEVLQGGSQRSIAPRTHPYSPKSEAPRTTRDEKRRAQHNEVER 100 110 120 130 140 150 210 220 230 240 250 260 pF1KB8 RRRDKINNWIVQLSKIIPDCSMESTKSGQSKGGILSKACDYIQELRQSNHRLSEELQGLD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_996 RRRDKINNWIVQLSKIIPDCSMESTKSGQSKGGILSKACDYIQELRQSNHRLSEELQGLD 160 170 180 190 200 210 270 280 290 300 310 pF1KB8 QLQLDNDVLRQQVEDLKNKNLLLRAQLRHHGLEVVIKNDSN ::::::::::::::::::::::::::::::::::::::::: NP_996 QLQLDNDVLRQQVEDLKNKNLLLRAQLRHHGLEVVIKNDSN 220 230 240 250 >>NP_997174 (OMIM: 600390) upstream stimulatory factor 2 (279 aa) initn: 909 init1: 749 opt: 756 Z-score: 676.2 bits: 133.1 E(85289): 6.3e-31 Smith-Waterman score: 891; 51.2% identity (73.6% similar) in 303 aa overlap (4-304:22-273) 10 20 30 40 pF1KB8 MKGQQKTAETEEGTVQIQEGAVATG-EDPTSVAIASIQSAAT ..: :.::: :..:::. . : :. :.:::.:.:.:: NP_997 MDMLDPGLDPAASATAAAAASHDKGPEAEEG-VELQEGGDGPGAEEQTAVAITSVQQAA- 10 20 30 40 50 50 60 70 80 90 100 pF1KB8 FPDPNVKYVFRTE-NGGQVMYRVIQVSEGQLDGQTEGTGAISGYPATQSMTQAVIQGAFT : : :..: :::: :::: ::::. :. NP_997 FGDHNIQYQFRTETNGGQ----------------------------------AVIQNPFS 60 70 80 110 120 130 140 150 160 pF1KB8 SDDAVDTEGTAAETHYTYFPSTAVGDGAGGTTSGSTAAVVTTQGSEALLGQATPPGTGQF . . .:....:....:::...::: .:: :..: .. :. : ::: NP_997 NGGSPAAEAVSGEARFAYFPASSVGD--------TTA--VSVQTTD----QSLQAG-GQF 90 100 110 120 170 180 190 200 210 220 pF1KB8 FVMMSPQEVLQGGSQRSIAPRTHPYSPKSEAPRTTRDEKRRAQHNEVERRRRDKINNWIV .:::.::.::: :.::.::::::::::: .. :: :::.::::::::::::::::::::: NP_997 YVMMTPQDVLQTGTQRTIAPRTHPYSPKIDGTRTPRDERRRAQHNEVERRRRDKINNWIV 130 140 150 160 170 180 230 240 250 260 270 280 pF1KB8 QLSKIIPDCSMESTKSGQSKGGILSKACDYIQELRQSNHRLSEELQGLDQLQLDNDVLRQ :::::::::. ...:.: :::::::::::::.::::.:.:..: .. ..::.::..::: NP_997 QLSKIIPDCNADNSKTGASKGGILSKACDYIRELRQTNQRMQETFKEAERLQMDNELLRQ 190 200 210 220 230 240 290 300 310 pF1KB8 QVEDLKNKNLLLRAQLRHHGLEVVIKNDSN :.:.:::.: ::::::..:.::.: NP_997 QIEELKNENALLRAQLQQHNLEMVGEGTRQ 250 260 270 >>NP_003358 (OMIM: 600390) upstream stimulatory factor 2 (346 aa) initn: 1000 init1: 749 opt: 756 Z-score: 674.9 bits: 133.2 E(85289): 7.5e-31 Smith-Waterman score: 1005; 51.5% identity (74.7% similar) in 336 aa overlap (4-304:22-340) 10 20 30 40 pF1KB8 MKGQQKTAETEEGTVQIQEGAVATG-EDPTSVAIASIQSAAT ..: :.::: :..:::. . : :. :.:::.:.:.:: NP_003 MDMLDPGLDPAASATAAAAASHDKGPEAEEG-VELQEGGDGPGAEEQTAVAITSVQQAA- 10 20 30 40 50 50 60 70 80 90 pF1KB8 FPDPNVKYVFRTE-NGGQVMYRVIQVSEGQLDGQTEGTGAISGYPAT------QSMTQ-- : : :..: :::: ::::: :::.::..:::::: . .::.: .. :..:: NP_003 FGDHNIQYQFRTETNGGQVTYRVVQVTDGQLDGQGDTAGAVSVVSTAAFAGGQQAVTQVG 60 70 80 90 100 110 100 110 120 pF1KB8 -------------------------AVIQGAFTSDDAVDTEGTAAETHYTYFPSTAVGDG ::::. :.. . .:....:....:::...::: NP_003 VDGAAQRPGPAAASVPPGPAAPFPLAVIQNPFSNGGSPAAEAVSGEARFAYFPASSVGD- 120 130 140 150 160 170 130 140 150 160 170 180 pF1KB8 AGGTTSGSTAAVVTTQGSEALLGQATPPGTGQFFVMMSPQEVLQGGSQRSIAPRTHPYSP .:: :..: .. :. : :::.:::.::.::: :.::.:::::::::: NP_003 -------TTA--VSVQTTD----QSLQAG-GQFYVMMTPQDVLQTGTQRTIAPRTHPYSP 180 190 200 210 220 190 200 210 220 230 240 pF1KB8 KSEAPRTTRDEKRRAQHNEVERRRRDKINNWIVQLSKIIPDCSMESTKSGQSKGGILSKA : .. :: :::.::::::::::::::::::::::::::::::. ...:.: ::::::::: NP_003 KIDGTRTPRDERRRAQHNEVERRRRDKINNWIVQLSKIIPDCNADNSKTGASKGGILSKA 230 240 250 260 270 280 250 260 270 280 290 300 pF1KB8 CDYIQELRQSNHRLSEELQGLDQLQLDNDVLRQQVEDLKNKNLLLRAQLRHHGLEVVIKN ::::.::::.:.:..: .. ..::.::..::::.:.:::.: ::::::..:.::.: NP_003 CDYIRELRQTNQRMQETFKEAERLQMDNELLRQQIEELKNENALLRAQLQQHNLEMVGEG 290 300 310 320 330 340 310 pF1KB8 DSN NP_003 TRQ >>NP_001308079 (OMIM: 600390) upstream stimulatory facto (215 aa) initn: 762 init1: 672 opt: 681 Z-score: 612.3 bits: 120.9 E(85289): 2.3e-27 Smith-Waterman score: 681; 53.6% identity (77.3% similar) in 207 aa overlap (102-304:9-209) 80 90 100 110 120 pF1KB8 DGQTEGTGAISGYPATQSMTQAVIQGAFTSDDAVDTEGTAAETHYTYFPSTAVG----DG : :... ..:: .: : . : .: NP_001 MDMLDPGLDPAASATAAAAASH-DKGPEAEEGVELQEG 10 20 30 130 140 150 160 170 180 pF1KB8 AGGTTSGSTAAVVTTQGSEALLGQATPPGTGQFFVMMSPQEVLQGGSQRSIAPRTHPYSP . : . .::. :. ..: .:. . :: . . : :.::.:::::::::: NP_001 GDGPGAEEQTAVAITSVQQAAFGDHNIQ--YQFRTETNGG---QTGTQRTIAPRTHPYSP 40 50 60 70 80 90 190 200 210 220 230 240 pF1KB8 KSEAPRTTRDEKRRAQHNEVERRRRDKINNWIVQLSKIIPDCSMESTKSGQSKGGILSKA : .. :: :::.::::::::::::::::::::::::::::::. ...:.: ::::::::: NP_001 KIDGTRTPRDERRRAQHNEVERRRRDKINNWIVQLSKIIPDCNADNSKTGASKGGILSKA 100 110 120 130 140 150 250 260 270 280 290 300 pF1KB8 CDYIQELRQSNHRLSEELQGLDQLQLDNDVLRQQVEDLKNKNLLLRAQLRHHGLEVVIKN ::::.::::.:.:..: .. ..::.::..::::.:.:::.: ::::::..:.::.: NP_001 CDYIRELRQTNQRMQETFKEAERLQMDNELLRQQIEELKNENALLRAQLQQHNLEMVGEG 160 170 180 190 200 210 310 pF1KB8 DSN NP_001 TRQ >>XP_016882688 (OMIM: 600390) PREDICTED: upstream stimul (284 aa) initn: 815 init1: 655 opt: 662 Z-score: 594.0 bits: 117.9 E(85289): 2.4e-26 Smith-Waterman score: 797; 50.2% identity (71.9% similar) in 281 aa overlap (4-282:22-251) 10 20 30 40 pF1KB8 MKGQQKTAETEEGTVQIQEGAVATG-EDPTSVAIASIQSAAT ..: :.::: :..:::. . : :. :.:::.:.:.:: XP_016 MDMLDPGLDPAASATAAAAASHDKGPEAEEG-VELQEGGDGPGAEEQTAVAITSVQQAA- 10 20 30 40 50 50 60 70 80 90 100 pF1KB8 FPDPNVKYVFRTE-NGGQVMYRVIQVSEGQLDGQTEGTGAISGYPATQSMTQAVIQGAFT : : :..: :::: :::: ::::. :. XP_016 FGDHNIQYQFRTETNGGQ----------------------------------AVIQNPFS 60 70 80 110 120 130 140 150 160 pF1KB8 SDDAVDTEGTAAETHYTYFPSTAVGDGAGGTTSGSTAAVVTTQGSEALLGQATPPGTGQF . . .:....:....:::...::: .:: :..: .. :. : ::: XP_016 NGGSPAAEAVSGEARFAYFPASSVGD--------TTA--VSVQTTD----QSLQAG-GQF 90 100 110 120 170 180 190 200 210 220 pF1KB8 FVMMSPQEVLQGGSQRSIAPRTHPYSPKSEAPRTTRDEKRRAQHNEVERRRRDKINNWIV .:::.::.::: :.::.::::::::::: .. :: :::.::::::::::::::::::::: XP_016 YVMMTPQDVLQTGTQRTIAPRTHPYSPKIDGTRTPRDERRRAQHNEVERRRRDKINNWIV 130 140 150 160 170 180 230 240 250 260 270 280 pF1KB8 QLSKIIPDCSMESTKSGQSKGGILSKACDYIQELRQSNHRLSEELQGLDQLQLDNDVLRQ :::::::::. ...:.: :::::::::::::.::::.:.:..: .. ..::.::..::: XP_016 QLSKIIPDCNADNSKTGASKGGILSKACDYIRELRQTNQRMQETFKEAERLQMDNELLRQ 190 200 210 220 230 240 290 300 310 pF1KB8 QVEDLKNKNLLLRAQLRHHGLEVVIKNDSN :: XP_016 QVGAGPGAGQGPGAPDARRWPSAPLTSVVSARSRS 250 260 270 280 >>XP_005259254 (OMIM: 600390) PREDICTED: upstream stimul (351 aa) initn: 906 init1: 655 opt: 662 Z-score: 592.7 bits: 118.0 E(85289): 2.8e-26 Smith-Waterman score: 911; 50.6% identity (73.2% similar) in 314 aa overlap (4-282:22-318) 10 20 30 40 pF1KB8 MKGQQKTAETEEGTVQIQEGAVATG-EDPTSVAIASIQSAAT ..: :.::: :..:::. . : :. :.:::.:.:.:: XP_005 MDMLDPGLDPAASATAAAAASHDKGPEAEEG-VELQEGGDGPGAEEQTAVAITSVQQAA- 10 20 30 40 50 50 60 70 80 90 pF1KB8 FPDPNVKYVFRTE-NGGQVMYRVIQVSEGQLDGQTEGTGAISGYPAT------QSMTQ-- : : :..: :::: ::::: :::.::..:::::: . .::.: .. :..:: XP_005 FGDHNIQYQFRTETNGGQVTYRVVQVTDGQLDGQGDTAGAVSVVSTAAFAGGQQAVTQVG 60 70 80 90 100 110 100 110 120 pF1KB8 -------------------------AVIQGAFTSDDAVDTEGTAAETHYTYFPSTAVGDG ::::. :.. . .:....:....:::...::: XP_005 VDGAAQRPGPAAASVPPGPAAPFPLAVIQNPFSNGGSPAAEAVSGEARFAYFPASSVGD- 120 130 140 150 160 170 130 140 150 160 170 180 pF1KB8 AGGTTSGSTAAVVTTQGSEALLGQATPPGTGQFFVMMSPQEVLQGGSQRSIAPRTHPYSP .:: :..: .. :. : :::.:::.::.::: :.::.:::::::::: XP_005 -------TTA--VSVQTTD----QSLQAG-GQFYVMMTPQDVLQTGTQRTIAPRTHPYSP 180 190 200 210 220 190 200 210 220 230 240 pF1KB8 KSEAPRTTRDEKRRAQHNEVERRRRDKINNWIVQLSKIIPDCSMESTKSGQSKGGILSKA : .. :: :::.::::::::::::::::::::::::::::::. ...:.: ::::::::: XP_005 KIDGTRTPRDERRRAQHNEVERRRRDKINNWIVQLSKIIPDCNADNSKTGASKGGILSKA 230 240 250 260 270 280 250 260 270 280 290 300 pF1KB8 CDYIQELRQSNHRLSEELQGLDQLQLDNDVLRQQVEDLKNKNLLLRAQLRHHGLEVVIKN ::::.::::.:.:..: .. ..::.::..::::: XP_005 CDYIRELRQTNQRMQETFKEAERLQMDNELLRQQVGAGPGAGQGPGAPDARRWPSAPLTS 290 300 310 320 330 340 310 pF1KB8 DSN XP_005 VVSARSRS 350 >>XP_011525563 (OMIM: 600390) PREDICTED: upstream stimul (244 aa) initn: 527 init1: 276 opt: 283 Z-score: 263.8 bits: 56.6 E(85289): 5.9e-08 Smith-Waterman score: 532; 44.4% identity (66.9% similar) in 239 aa overlap (4-207:22-243) 10 20 30 40 pF1KB8 MKGQQKTAETEEGTVQIQEGAVATG-EDPTSVAIASIQSAAT ..: :.::: :..:::. . : :. :.:::.:.:.:: XP_011 MDMLDPGLDPAASATAAAAASHDKGPEAEEG-VELQEGGDGPGAEEQTAVAITSVQQAA- 10 20 30 40 50 50 60 70 80 90 pF1KB8 FPDPNVKYVFRTE-NGGQVMYRVIQVSEGQLDGQTEGTGAISGYPAT------QSMTQ-- : : :..: :::: ::::: :::.::..:::::: . .::.: .. :..:: XP_011 FGDHNIQYQFRTETNGGQVTYRVVQVTDGQLDGQGDTAGAVSVVSTAAFAGGQQAVTQVG 60 70 80 90 100 110 100 110 120 pF1KB8 -------------------------AVIQGAFTSDDAVDTEGTAAETHYTYFPSTAVGDG ::::. :.. . .:....:....:::...::: XP_011 VDGAAQRPGPAAASVPPGPAAPFPLAVIQNPFSNGGSPAAEAVSGEARFAYFPASSVGD- 120 130 140 150 160 170 130 140 150 160 170 180 pF1KB8 AGGTTSGSTAAVVTTQGSEALLGQATPPGTGQFFVMMSPQEVLQGGSQRSIAPRTHPYSP .:: :..: .. :. : :::.:::.::.::: :.::.:::::::::: XP_011 -------TTA--VSVQTTD----QSLQAG-GQFYVMMTPQDVLQTGTQRTIAPRTHPYSP 180 190 200 210 220 190 200 210 220 230 240 pF1KB8 KSEAPRTTRDEKRRAQHNEVERRRRDKINNWIVQLSKIIPDCSMESTKSGQSKGGILSKA : .. :: :::.:::::::: XP_011 KIDGTRTPRDERRRAQHNEVP 230 240 >>XP_011525562 (OMIM: 600390) PREDICTED: upstream stimul (258 aa) initn: 522 init1: 271 opt: 281 Z-score: 261.7 bits: 56.3 E(85289): 7.7e-08 Smith-Waterman score: 530; 42.6% identity (64.9% similar) in 251 aa overlap (4-219:22-255) 10 20 30 40 pF1KB8 MKGQQKTAETEEGTVQIQEGAVATG-EDPTSVAIASIQSAAT ..: :.::: :..:::. . : :. :.:::.:.:.:: XP_011 MDMLDPGLDPAASATAAAAASHDKGPEAEEG-VELQEGGDGPGAEEQTAVAITSVQQAA- 10 20 30 40 50 50 60 70 80 90 pF1KB8 FPDPNVKYVFRTE-NGGQVMYRVIQVSEGQLDGQTEGTGAISGYPAT------QSMTQ-- : : :..: :::: ::::: :::.::..:::::: . .::.: .. :..:: XP_011 FGDHNIQYQFRTETNGGQVTYRVVQVTDGQLDGQGDTAGAVSVVSTAAFAGGQQAVTQVG 60 70 80 90 100 110 100 110 120 pF1KB8 -------------------------AVIQGAFTSDDAVDTEGTAAETHYTYFPSTAVGDG ::::. :.. . .:....:....:::...::: XP_011 VDGAAQRPGPAAASVPPGPAAPFPLAVIQNPFSNGGSPAAEAVSGEARFAYFPASSVGD- 120 130 140 150 160 170 130 140 150 160 170 180 pF1KB8 AGGTTSGSTAAVVTTQGSEALLGQATPPGTGQFFVMMSPQEVLQGGSQRSIAPRTHPYSP .:: :..: .. :. : :::.:::.::.::: :.::.:::::::::: XP_011 -------TTA--VSVQTTD----QSLQAG-GQFYVMMTPQDVLQTGTQRTIAPRTHPYSP 180 190 200 210 220 190 200 210 220 230 240 pF1KB8 KSEAPRTTRDEKRRAQHNEVERRRRDKINNWIVQLSKIIPDCSMESTKSGQSKGGILSKA : .. :: :::.::::::: : .:. XP_011 KIDGTRTPRDERRRAQHNEGLWSRWGLHCSWVSLG 230 240 250 250 260 270 280 290 300 pF1KB8 CDYIQELRQSNHRLSEELQGLDQLQLDNDVLRQQVEDLKNKNLLLRAQLRHHGLEVVIKN 310 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 11:54:14 2016 done: Fri Nov 4 11:54:14 2016 Total Scan time: 5.710 Total Display time: 0.030 Function used was FASTA [36.3.4 Apr, 2011]