FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB8346, 127 aa 1>>>pF1KB8346 127 - 127 aa - 127 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.6527+/-0.00028; mu= 9.8713+/- 0.018 mean_var=82.8738+/-16.810, 0's: 0 Z-trim(119.3): 10 B-trim: 1697 in 1/51 Lambda= 0.140885 statistics sampled from 33156 (33166) to 33156 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.768), E-opt: 0.2 (0.389), width: 16 Scan time: 4.490 The best scores are: opt bits E(85289) NP_001028284 (OMIM: 605604) polyadenylate-binding ( 127) 863 184.0 5.6e-47 XP_016865012 (OMIM: 605604) PREDICTED: polyadenyla ( 127) 863 184.0 5.6e-47 NP_057564 (OMIM: 605604) polyadenylate-binding pro ( 127) 863 184.0 5.6e-47 XP_016865011 (OMIM: 605604) PREDICTED: polyadenyla ( 127) 863 184.0 5.6e-47 XP_011541730 (OMIM: 605604) PREDICTED: polyadenyla ( 127) 863 184.0 5.6e-47 NP_065192 (OMIM: 611018) polyadenylate-binding pro ( 123) 531 116.5 1.1e-26 XP_011531145 (OMIM: 611018) PREDICTED: polyadenyla ( 123) 531 116.5 1.1e-26 XP_005264368 (OMIM: 611018) PREDICTED: polyadenyla ( 123) 531 116.5 1.1e-26 XP_005264367 (OMIM: 611018) PREDICTED: polyadenyla ( 123) 531 116.5 1.1e-26 XP_011531144 (OMIM: 611018) PREDICTED: polyadenyla ( 144) 531 116.6 1.3e-26 >>NP_001028284 (OMIM: 605604) polyadenylate-binding prot (127 aa) initn: 863 init1: 863 opt: 863 Z-score: 964.4 bits: 184.0 E(85289): 5.6e-47 Smith-Waterman score: 863; 99.2% identity (100.0% similar) in 127 aa overlap (1-127:1-127) 10 20 30 40 50 60 pF1KB8 MKDPSRSSTSPSIINEDVIINGHSHEDDNPFAEYMWMENEEEFNRQIEEELWEEEFIERC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MKDPSRSSTSPSIINEDVIINGHSHEDDNPFAEYMWMENEEEFNRQIEEELWEEEFIERC 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 FQEMLEEEEEHEWFIPARDLPQTMDQIQDQFNDLVISEGSSLEDLVVKSNLNPNAKEFVP :::::::::::::::::::::::::::::::::::::.:::::::::::::::::::::: NP_001 FQEMLEEEEEHEWFIPARDLPQTMDQIQDQFNDLVISDGSSLEDLVVKSNLNPNAKEFVP 70 80 90 100 110 120 pF1KB8 GVKYGNI ::::::: NP_001 GVKYGNI >>XP_016865012 (OMIM: 605604) PREDICTED: polyadenylate-b (127 aa) initn: 863 init1: 863 opt: 863 Z-score: 964.4 bits: 184.0 E(85289): 5.6e-47 Smith-Waterman score: 863; 99.2% identity (100.0% similar) in 127 aa overlap (1-127:1-127) 10 20 30 40 50 60 pF1KB8 MKDPSRSSTSPSIINEDVIINGHSHEDDNPFAEYMWMENEEEFNRQIEEELWEEEFIERC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MKDPSRSSTSPSIINEDVIINGHSHEDDNPFAEYMWMENEEEFNRQIEEELWEEEFIERC 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 FQEMLEEEEEHEWFIPARDLPQTMDQIQDQFNDLVISEGSSLEDLVVKSNLNPNAKEFVP :::::::::::::::::::::::::::::::::::::.:::::::::::::::::::::: XP_016 FQEMLEEEEEHEWFIPARDLPQTMDQIQDQFNDLVISDGSSLEDLVVKSNLNPNAKEFVP 70 80 90 100 110 120 pF1KB8 GVKYGNI ::::::: XP_016 GVKYGNI >>NP_057564 (OMIM: 605604) polyadenylate-binding protein (127 aa) initn: 863 init1: 863 opt: 863 Z-score: 964.4 bits: 184.0 E(85289): 5.6e-47 Smith-Waterman score: 863; 99.2% identity (100.0% similar) in 127 aa overlap (1-127:1-127) 10 20 30 40 50 60 pF1KB8 MKDPSRSSTSPSIINEDVIINGHSHEDDNPFAEYMWMENEEEFNRQIEEELWEEEFIERC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_057 MKDPSRSSTSPSIINEDVIINGHSHEDDNPFAEYMWMENEEEFNRQIEEELWEEEFIERC 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 FQEMLEEEEEHEWFIPARDLPQTMDQIQDQFNDLVISEGSSLEDLVVKSNLNPNAKEFVP :::::::::::::::::::::::::::::::::::::.:::::::::::::::::::::: NP_057 FQEMLEEEEEHEWFIPARDLPQTMDQIQDQFNDLVISDGSSLEDLVVKSNLNPNAKEFVP 70 80 90 100 110 120 pF1KB8 GVKYGNI ::::::: NP_057 GVKYGNI >>XP_016865011 (OMIM: 605604) PREDICTED: polyadenylate-b (127 aa) initn: 863 init1: 863 opt: 863 Z-score: 964.4 bits: 184.0 E(85289): 5.6e-47 Smith-Waterman score: 863; 99.2% identity (100.0% similar) in 127 aa overlap (1-127:1-127) 10 20 30 40 50 60 pF1KB8 MKDPSRSSTSPSIINEDVIINGHSHEDDNPFAEYMWMENEEEFNRQIEEELWEEEFIERC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MKDPSRSSTSPSIINEDVIINGHSHEDDNPFAEYMWMENEEEFNRQIEEELWEEEFIERC 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 FQEMLEEEEEHEWFIPARDLPQTMDQIQDQFNDLVISEGSSLEDLVVKSNLNPNAKEFVP :::::::::::::::::::::::::::::::::::::.:::::::::::::::::::::: XP_016 FQEMLEEEEEHEWFIPARDLPQTMDQIQDQFNDLVISDGSSLEDLVVKSNLNPNAKEFVP 70 80 90 100 110 120 pF1KB8 GVKYGNI ::::::: XP_016 GVKYGNI >>XP_011541730 (OMIM: 605604) PREDICTED: polyadenylate-b (127 aa) initn: 863 init1: 863 opt: 863 Z-score: 964.4 bits: 184.0 E(85289): 5.6e-47 Smith-Waterman score: 863; 99.2% identity (100.0% similar) in 127 aa overlap (1-127:1-127) 10 20 30 40 50 60 pF1KB8 MKDPSRSSTSPSIINEDVIINGHSHEDDNPFAEYMWMENEEEFNRQIEEELWEEEFIERC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MKDPSRSSTSPSIINEDVIINGHSHEDDNPFAEYMWMENEEEFNRQIEEELWEEEFIERC 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 FQEMLEEEEEHEWFIPARDLPQTMDQIQDQFNDLVISEGSSLEDLVVKSNLNPNAKEFVP :::::::::::::::::::::::::::::::::::::.:::::::::::::::::::::: XP_011 FQEMLEEEEEHEWFIPARDLPQTMDQIQDQFNDLVISDGSSLEDLVVKSNLNPNAKEFVP 70 80 90 100 110 120 pF1KB8 GVKYGNI ::::::: XP_011 GVKYGNI >>NP_065192 (OMIM: 611018) polyadenylate-binding protein (123 aa) initn: 287 init1: 268 opt: 531 Z-score: 599.9 bits: 116.5 E(85289): 1.1e-26 Smith-Waterman score: 531; 60.8% identity (85.6% similar) in 125 aa overlap (1-124:1-123) 10 20 30 40 50 pF1KB8 MKDPSRSSTSPSIIN-EDVIINGHSHEDDNPFAEYMWMENEEEFNRQIEEELWEEEFIER :. . ..::::. . :: ..::. : .:::::::::::::.::::.:::: :..:..: NP_065 MNGSNMANTSPSVKSKEDQGLSGHD-EKENPFAEYMWMENEEDFNRQVEEELQEQDFLDR 10 20 30 40 50 60 70 80 90 100 110 pF1KB8 CFQEMLEEEEEHEWFIPARDLPQTMDQIQDQFNDLVISEGSSLEDLVVKSNLNPNAKEFV ::::::.::.. .::::.:::::.: :.:.:.: : .::: . ::.. ::::::.::::. NP_065 CFQEMLDEEDQ-DWFIPSRDLPQAMGQLQQQLNGLSVSEGHDSEDILSKSNLNPDAKEFI 60 70 80 90 100 110 120 pF1KB8 PGVKYGNI :: :: NP_065 PGEKY 120 >>XP_011531145 (OMIM: 611018) PREDICTED: polyadenylate-b (123 aa) initn: 287 init1: 268 opt: 531 Z-score: 599.9 bits: 116.5 E(85289): 1.1e-26 Smith-Waterman score: 531; 60.8% identity (85.6% similar) in 125 aa overlap (1-124:1-123) 10 20 30 40 50 pF1KB8 MKDPSRSSTSPSIIN-EDVIINGHSHEDDNPFAEYMWMENEEEFNRQIEEELWEEEFIER :. . ..::::. . :: ..::. : .:::::::::::::.::::.:::: :..:..: XP_011 MNGSNMANTSPSVKSKEDQGLSGHD-EKENPFAEYMWMENEEDFNRQVEEELQEQDFLDR 10 20 30 40 50 60 70 80 90 100 110 pF1KB8 CFQEMLEEEEEHEWFIPARDLPQTMDQIQDQFNDLVISEGSSLEDLVVKSNLNPNAKEFV ::::::.::.. .::::.:::::.: :.:.:.: : .::: . ::.. ::::::.::::. XP_011 CFQEMLDEEDQ-DWFIPSRDLPQAMGQLQQQLNGLSVSEGHDSEDILSKSNLNPDAKEFI 60 70 80 90 100 110 120 pF1KB8 PGVKYGNI :: :: XP_011 PGEKY 120 >>XP_005264368 (OMIM: 611018) PREDICTED: polyadenylate-b (123 aa) initn: 287 init1: 268 opt: 531 Z-score: 599.9 bits: 116.5 E(85289): 1.1e-26 Smith-Waterman score: 531; 60.8% identity (85.6% similar) in 125 aa overlap (1-124:1-123) 10 20 30 40 50 pF1KB8 MKDPSRSSTSPSIIN-EDVIINGHSHEDDNPFAEYMWMENEEEFNRQIEEELWEEEFIER :. . ..::::. . :: ..::. : .:::::::::::::.::::.:::: :..:..: XP_005 MNGSNMANTSPSVKSKEDQGLSGHD-EKENPFAEYMWMENEEDFNRQVEEELQEQDFLDR 10 20 30 40 50 60 70 80 90 100 110 pF1KB8 CFQEMLEEEEEHEWFIPARDLPQTMDQIQDQFNDLVISEGSSLEDLVVKSNLNPNAKEFV ::::::.::.. .::::.:::::.: :.:.:.: : .::: . ::.. ::::::.::::. XP_005 CFQEMLDEEDQ-DWFIPSRDLPQAMGQLQQQLNGLSVSEGHDSEDILSKSNLNPDAKEFI 60 70 80 90 100 110 120 pF1KB8 PGVKYGNI :: :: XP_005 PGEKY 120 >>XP_005264367 (OMIM: 611018) PREDICTED: polyadenylate-b (123 aa) initn: 287 init1: 268 opt: 531 Z-score: 599.9 bits: 116.5 E(85289): 1.1e-26 Smith-Waterman score: 531; 60.8% identity (85.6% similar) in 125 aa overlap (1-124:1-123) 10 20 30 40 50 pF1KB8 MKDPSRSSTSPSIIN-EDVIINGHSHEDDNPFAEYMWMENEEEFNRQIEEELWEEEFIER :. . ..::::. . :: ..::. : .:::::::::::::.::::.:::: :..:..: XP_005 MNGSNMANTSPSVKSKEDQGLSGHD-EKENPFAEYMWMENEEDFNRQVEEELQEQDFLDR 10 20 30 40 50 60 70 80 90 100 110 pF1KB8 CFQEMLEEEEEHEWFIPARDLPQTMDQIQDQFNDLVISEGSSLEDLVVKSNLNPNAKEFV ::::::.::.. .::::.:::::.: :.:.:.: : .::: . ::.. ::::::.::::. XP_005 CFQEMLDEEDQ-DWFIPSRDLPQAMGQLQQQLNGLSVSEGHDSEDILSKSNLNPDAKEFI 60 70 80 90 100 110 120 pF1KB8 PGVKYGNI :: :: XP_005 PGEKY 120 >>XP_011531144 (OMIM: 611018) PREDICTED: polyadenylate-b (144 aa) initn: 290 init1: 268 opt: 531 Z-score: 599.0 bits: 116.6 E(85289): 1.3e-26 Smith-Waterman score: 531; 60.8% identity (85.6% similar) in 125 aa overlap (1-124:22-144) 10 20 30 pF1KB8 MKDPSRSSTSPSIIN-EDVIINGHSHEDDNPFAEYMWME :. . ..::::. . :: ..::. : .:::::::::: XP_011 MPHLPGRRSPLLLCLAVRSIIMNGSNMANTSPSVKSKEDQGLSGHD-EKENPFAEYMWME 10 20 30 40 50 40 50 60 70 80 90 pF1KB8 NEEEFNRQIEEELWEEEFIERCFQEMLEEEEEHEWFIPARDLPQTMDQIQDQFNDLVISE :::.::::.:::: :..:..:::::::.::.. .::::.:::::.: :.:.:.: : .:: XP_011 NEEDFNRQVEEELQEQDFLDRCFQEMLDEEDQ-DWFIPSRDLPQAMGQLQQQLNGLSVSE 60 70 80 90 100 110 100 110 120 pF1KB8 GSSLEDLVVKSNLNPNAKEFVPGVKYGNI : . ::.. ::::::.::::.:: :: XP_011 GHDSEDILSKSNLNPDAKEFIPGEKY 120 130 140 127 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 11:58:19 2016 done: Fri Nov 4 11:58:20 2016 Total Scan time: 4.490 Total Display time: -0.030 Function used was FASTA [36.3.4 Apr, 2011]