FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB8354, 457 aa 1>>>pF1KB8354 457 - 457 aa - 457 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.7383+/-0.000433; mu= 15.5225+/- 0.027 mean_var=83.4637+/-16.296, 0's: 0 Z-trim(111.1): 118 B-trim: 0 in 0/52 Lambda= 0.140386 statistics sampled from 19466 (19588) to 19466 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.581), E-opt: 0.2 (0.23), width: 16 Scan time: 8.830 The best scores are: opt bits E(85289) NP_001139248 (OMIM: 602623,608516) peptidyl-prolyl ( 457) 3026 623.2 4.3e-178 NP_004108 (OMIM: 602623,608516) peptidyl-prolyl ci ( 457) 3026 623.2 4.3e-178 NP_001139247 (OMIM: 602623,608516) peptidyl-prolyl ( 457) 3026 623.2 4.3e-178 NP_002005 (OMIM: 600611) peptidyl-prolyl cis-trans ( 459) 1730 360.8 4.5e-99 XP_011519231 (OMIM: 600611) PREDICTED: peptidyl-pr ( 414) 1616 337.6 3.7e-92 NP_001139249 (OMIM: 602623,608516) peptidyl-prolyl ( 268) 1501 314.2 2.7e-85 NP_004107 (OMIM: 600620) peptidyl-prolyl cis-trans ( 108) 325 75.8 6.5e-14 NP_000792 (OMIM: 186945) peptidyl-prolyl cis-trans ( 108) 321 75.0 1.1e-13 NP_463460 (OMIM: 186945) peptidyl-prolyl cis-trans ( 108) 321 75.0 1.1e-13 XP_005273905 (OMIM: 186946) PREDICTED: peptidyl-pr ( 142) 318 74.4 2.2e-13 NP_476433 (OMIM: 186946) peptidyl-prolyl cis-trans ( 142) 318 74.4 2.2e-13 NP_001128680 (OMIM: 186946) peptidyl-prolyl cis-tr ( 142) 318 74.4 2.2e-13 NP_004461 (OMIM: 186946) peptidyl-prolyl cis-trans ( 142) 318 74.4 2.2e-13 NP_068758 (OMIM: 259450,607063,610968) peptidyl-pr ( 582) 297 70.6 1.3e-11 XP_011523401 (OMIM: 259450,607063,610968) PREDICTE ( 601) 297 70.6 1.3e-11 XP_011513417 (OMIM: 616257) PREDICTED: peptidyl-pr ( 359) 290 69.0 2.3e-11 NP_009201 (OMIM: 616257) peptidyl-prolyl cis-trans ( 570) 290 69.2 3.4e-11 NP_001271270 (OMIM: 616257) peptidyl-prolyl cis-tr ( 623) 289 69.0 4.2e-11 NP_001309892 (OMIM: 600620) peptidyl-prolyl cis-tr ( 79) 272 65.0 8.6e-11 XP_016859085 (OMIM: 600620) PREDICTED: peptidyl-pr ( 79) 272 65.0 8.6e-11 XP_016859084 (OMIM: 600620) PREDICTED: peptidyl-pr ( 79) 272 65.0 8.6e-11 XP_016859083 (OMIM: 600620) PREDICTED: peptidyl-pr ( 79) 272 65.0 8.6e-11 XP_016859082 (OMIM: 600620) PREDICTED: peptidyl-pr ( 79) 272 65.0 8.6e-11 NP_001309893 (OMIM: 600620) peptidyl-prolyl cis-tr ( 79) 272 65.0 8.6e-11 NP_003593 (OMIM: 604839) inactive peptidyl-prolyl ( 327) 280 67.0 8.8e-11 XP_016868231 (OMIM: 604839) PREDICTED: inactive pe ( 266) 274 65.7 1.7e-10 XP_006716216 (OMIM: 604839) PREDICTED: inactive pe ( 282) 274 65.7 1.8e-10 XP_016868230 (OMIM: 604839) PREDICTED: inactive pe ( 317) 274 65.8 2e-10 NP_001128683 (OMIM: 604839) inactive peptidyl-prol ( 322) 274 65.8 2e-10 XP_011526165 (OMIM: 604840) PREDICTED: peptidyl-pr ( 413) 273 65.6 2.8e-10 NP_036313 (OMIM: 604840) peptidyl-prolyl cis-trans ( 413) 273 65.6 2.8e-10 NP_005029 (OMIM: 601753) peptidyl-prolyl cis-trans ( 370) 270 65.0 3.9e-10 XP_011534867 (OMIM: 186947) PREDICTED: peptidyl-pr ( 191) 266 64.0 4.1e-10 NP_071393 (OMIM: 617076) FK506-binding protein-lik ( 349) 269 64.8 4.3e-10 NP_002004 (OMIM: 186947) peptidyl-prolyl cis-trans ( 224) 266 64.0 4.6e-10 NP_001128684 (OMIM: 607062) peptidyl-prolyl cis-tr ( 221) 236 58.0 3.1e-08 NP_851939 (OMIM: 607062) peptidyl-prolyl cis-trans ( 222) 227 56.1 1.1e-07 XP_011523402 (OMIM: 259450,607063,610968) PREDICTE ( 510) 230 57.0 1.4e-07 NP_001028226 (OMIM: 268000,604392,604393) aryl-hyd ( 321) 220 54.8 3.9e-07 NP_001028227 (OMIM: 268000,604392,604393) aryl-hyd ( 324) 220 54.8 4e-07 NP_001272331 (OMIM: 268000,604392,604393) aryl-hyd ( 345) 220 54.8 4.2e-07 NP_001272329 (OMIM: 268000,604392,604393) aryl-hyd ( 362) 220 54.9 4.3e-07 NP_001272328 (OMIM: 268000,604392,604393) aryl-hyd ( 372) 220 54.9 4.4e-07 NP_055151 (OMIM: 268000,604392,604393) aryl-hydroc ( 384) 220 54.9 4.5e-07 NP_003968 (OMIM: 102200,219090,600634,605555) AH r ( 330) 219 54.6 4.6e-07 NP_001289888 (OMIM: 102200,219090,600634,605555) A ( 271) 212 53.2 1.1e-06 XP_016876582 (OMIM: 186947) PREDICTED: peptidyl-pr ( 196) 210 52.7 1.1e-06 NP_060416 (OMIM: 614505,614557) peptidyl-prolyl ci ( 211) 210 52.7 1.1e-06 XP_016876581 (OMIM: 186947) PREDICTED: peptidyl-pr ( 229) 210 52.7 1.2e-06 NP_473374 (OMIM: 600620) peptidyl-prolyl cis-trans ( 80) 202 50.8 1.6e-06 >>NP_001139248 (OMIM: 602623,608516) peptidyl-prolyl cis (457 aa) initn: 3026 init1: 3026 opt: 3026 Z-score: 3318.2 bits: 623.2 E(85289): 4.3e-178 Smith-Waterman score: 3026; 100.0% identity (100.0% similar) in 457 aa overlap (1-457:1-457) 10 20 30 40 50 60 pF1KB8 MTTDEGAKNNEESPTATVAEQGEDITSKKDRGVLKIVKRVGNGEETPMIGDKVYVHYKGK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MTTDEGAKNNEESPTATVAEQGEDITSKKDRGVLKIVKRVGNGEETPMIGDKVYVHYKGK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 LSNGKKFDSSHDRNEPFVFSLGKGQVIKAWDIGVATMKKGEICHLLCKPEYAYGSAGSLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LSNGKKFDSSHDRNEPFVFSLGKGQVIKAWDIGVATMKKGEICHLLCKPEYAYGSAGSLP 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 KIPSNATLFFEIELLDFKGEDLFEDGGIIRRTKRKGEGYSNPNEGATVEIHLEGRCGGRM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KIPSNATLFFEIELLDFKGEDLFEDGGIIRRTKRKGEGYSNPNEGATVEIHLEGRCGGRM 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 FDCRDVAFTVGEGEDHDIPIGIDKALEKMQREEQCILYLGPRYGFGEAGKPKFGIEPNAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FDCRDVAFTVGEGEDHDIPIGIDKALEKMQREEQCILYLGPRYGFGEAGKPKFGIEPNAE 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 LIYEVTLKSFEKAKESWEMDTKEKLEQAAIVKEKGTVYFKGGKYMQAVIQYGKIVSWLEM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LIYEVTLKSFEKAKESWEMDTKEKLEQAAIVKEKGTVYFKGGKYMQAVIQYGKIVSWLEM 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 EYGLSEKESKASESFLLAAFLNLAMCYLKLREYTKAVECCDKALGLDSANEKGLYRRGEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EYGLSEKESKASESFLLAAFLNLAMCYLKLREYTKAVECCDKALGLDSANEKGLYRRGEA 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB8 QLLMNEFESAKGDFEKVLEVNPQNKAARLQISMCQKKAKEHNERDRRIYANMFKKFAEQD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QLLMNEFESAKGDFEKVLEVNPQNKAARLQISMCQKKAKEHNERDRRIYANMFKKFAEQD 370 380 390 400 410 420 430 440 450 pF1KB8 AKEEANKAMGKKTSEGVTNEKGTDSQAMEEEKPEGHV ::::::::::::::::::::::::::::::::::::: NP_001 AKEEANKAMGKKTSEGVTNEKGTDSQAMEEEKPEGHV 430 440 450 >>NP_004108 (OMIM: 602623,608516) peptidyl-prolyl cis-tr (457 aa) initn: 3026 init1: 3026 opt: 3026 Z-score: 3318.2 bits: 623.2 E(85289): 4.3e-178 Smith-Waterman score: 3026; 100.0% identity (100.0% similar) in 457 aa overlap (1-457:1-457) 10 20 30 40 50 60 pF1KB8 MTTDEGAKNNEESPTATVAEQGEDITSKKDRGVLKIVKRVGNGEETPMIGDKVYVHYKGK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 MTTDEGAKNNEESPTATVAEQGEDITSKKDRGVLKIVKRVGNGEETPMIGDKVYVHYKGK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 LSNGKKFDSSHDRNEPFVFSLGKGQVIKAWDIGVATMKKGEICHLLCKPEYAYGSAGSLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 LSNGKKFDSSHDRNEPFVFSLGKGQVIKAWDIGVATMKKGEICHLLCKPEYAYGSAGSLP 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 KIPSNATLFFEIELLDFKGEDLFEDGGIIRRTKRKGEGYSNPNEGATVEIHLEGRCGGRM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 KIPSNATLFFEIELLDFKGEDLFEDGGIIRRTKRKGEGYSNPNEGATVEIHLEGRCGGRM 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 FDCRDVAFTVGEGEDHDIPIGIDKALEKMQREEQCILYLGPRYGFGEAGKPKFGIEPNAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 FDCRDVAFTVGEGEDHDIPIGIDKALEKMQREEQCILYLGPRYGFGEAGKPKFGIEPNAE 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 LIYEVTLKSFEKAKESWEMDTKEKLEQAAIVKEKGTVYFKGGKYMQAVIQYGKIVSWLEM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 LIYEVTLKSFEKAKESWEMDTKEKLEQAAIVKEKGTVYFKGGKYMQAVIQYGKIVSWLEM 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 EYGLSEKESKASESFLLAAFLNLAMCYLKLREYTKAVECCDKALGLDSANEKGLYRRGEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 EYGLSEKESKASESFLLAAFLNLAMCYLKLREYTKAVECCDKALGLDSANEKGLYRRGEA 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB8 QLLMNEFESAKGDFEKVLEVNPQNKAARLQISMCQKKAKEHNERDRRIYANMFKKFAEQD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 QLLMNEFESAKGDFEKVLEVNPQNKAARLQISMCQKKAKEHNERDRRIYANMFKKFAEQD 370 380 390 400 410 420 430 440 450 pF1KB8 AKEEANKAMGKKTSEGVTNEKGTDSQAMEEEKPEGHV ::::::::::::::::::::::::::::::::::::: NP_004 AKEEANKAMGKKTSEGVTNEKGTDSQAMEEEKPEGHV 430 440 450 >>NP_001139247 (OMIM: 602623,608516) peptidyl-prolyl cis (457 aa) initn: 3026 init1: 3026 opt: 3026 Z-score: 3318.2 bits: 623.2 E(85289): 4.3e-178 Smith-Waterman score: 3026; 100.0% identity (100.0% similar) in 457 aa overlap (1-457:1-457) 10 20 30 40 50 60 pF1KB8 MTTDEGAKNNEESPTATVAEQGEDITSKKDRGVLKIVKRVGNGEETPMIGDKVYVHYKGK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MTTDEGAKNNEESPTATVAEQGEDITSKKDRGVLKIVKRVGNGEETPMIGDKVYVHYKGK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 LSNGKKFDSSHDRNEPFVFSLGKGQVIKAWDIGVATMKKGEICHLLCKPEYAYGSAGSLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LSNGKKFDSSHDRNEPFVFSLGKGQVIKAWDIGVATMKKGEICHLLCKPEYAYGSAGSLP 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 KIPSNATLFFEIELLDFKGEDLFEDGGIIRRTKRKGEGYSNPNEGATVEIHLEGRCGGRM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KIPSNATLFFEIELLDFKGEDLFEDGGIIRRTKRKGEGYSNPNEGATVEIHLEGRCGGRM 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 FDCRDVAFTVGEGEDHDIPIGIDKALEKMQREEQCILYLGPRYGFGEAGKPKFGIEPNAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FDCRDVAFTVGEGEDHDIPIGIDKALEKMQREEQCILYLGPRYGFGEAGKPKFGIEPNAE 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 LIYEVTLKSFEKAKESWEMDTKEKLEQAAIVKEKGTVYFKGGKYMQAVIQYGKIVSWLEM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LIYEVTLKSFEKAKESWEMDTKEKLEQAAIVKEKGTVYFKGGKYMQAVIQYGKIVSWLEM 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 EYGLSEKESKASESFLLAAFLNLAMCYLKLREYTKAVECCDKALGLDSANEKGLYRRGEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EYGLSEKESKASESFLLAAFLNLAMCYLKLREYTKAVECCDKALGLDSANEKGLYRRGEA 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB8 QLLMNEFESAKGDFEKVLEVNPQNKAARLQISMCQKKAKEHNERDRRIYANMFKKFAEQD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QLLMNEFESAKGDFEKVLEVNPQNKAARLQISMCQKKAKEHNERDRRIYANMFKKFAEQD 370 380 390 400 410 420 430 440 450 pF1KB8 AKEEANKAMGKKTSEGVTNEKGTDSQAMEEEKPEGHV ::::::::::::::::::::::::::::::::::::: NP_001 AKEEANKAMGKKTSEGVTNEKGTDSQAMEEEKPEGHV 430 440 450 >>NP_002005 (OMIM: 600611) peptidyl-prolyl cis-trans iso (459 aa) initn: 1729 init1: 1125 opt: 1730 Z-score: 1899.6 bits: 360.8 E(85289): 4.5e-99 Smith-Waterman score: 1730; 55.2% identity (80.6% similar) in 458 aa overlap (1-450:1-458) 10 20 30 40 50 60 pF1KB8 MTTDEGAKNNEESPTATVAEQGEDITSKKDRGVLKIVKRVGNGEETPMIGDKVYVHYKGK ::..: .. . .: . .: ::. :.:.::::..:: :.: : :::::.:.::: : NP_002 MTAEEMKATESGAQSAPLPMEGVDISPKQDEGVLKVIKREGTGTEMPMIGDRVFVHYTGW 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 LSNGKKFDSSHDRNEPFVFSLGKGQVIKAWDIGVATMKKGEICHLLCKPEYAYGSAGSLP : .: ::::: ::.. : :.::::.:::::::..:::: ::.::. :::::::::::: : NP_002 LLDGTKFDSSLDRKDKFSFDLGKGEVIKAWDIAIATMKVGEVCHITCKPEYAYGSAGSPP 70 80 90 100 110 120 130 140 150 160 170 pF1KB8 KIPSNATLFFEIELLDFKGEDLFE--DGGIIRRTKRKGEGYSNPNEGATVEIHLEGRCGG ::: :::: ::.::..:::::: : ::::::: . .::::..::::: ::. ::: NP_002 KIPPNATLVFEVELFEFKGEDLTEEEDGGIIRRIQTRGEGYAKPNEGAIVEVALEGYYKD 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB8 RMFDCRDVAFTVGEGEDHDIPIGIDKALEKMQREEQCILYLGPRYGFGEAGKPKFGIEPN ..:: :.. : .::::. :.: :...:...:.. :. :.:: : :.:: .:: :: : :: NP_002 KLFDQRELRFEIGEGENLDLPYGLERAIQRMEKGEHSIVYLKPSYAFGSVGKEKFQIPPN 190 200 210 220 230 240 240 250 260 270 280 290 pF1KB8 AELIYEVTLKSFEKAKESWEMDTKEKLEQAAIVKEKGTVYFKGGKYMQAVIQYGKIVSWL ::: ::. :::::::::::::...:::::..::::.:::::: ::: ::..:: :::::: NP_002 AELKYELHLKSFEKAKESWEMNSEEKLEQSTIVKERGTVYFKEGKYKQALLQYKKIVSWL 250 260 270 280 290 300 300 310 320 330 340 350 pF1KB8 EMEYGLSEKESKASESFLLAAFLNLAMCYLKLREYTKAVECCDKALGLDSANEKGLYRRG :.: ..:..:.. .... ::. ::::::.:::. .. :.: :.::: ::: :::::.::: NP_002 EYESSFSNEEAQKAQALRLASHLNLAMCHLKLQAFSAAIESCNKALELDSNNEKGLFRRG 310 320 330 340 350 360 360 370 380 390 400 410 pF1KB8 EAQLLMNEFESAKGDFEKVLEVNPQNKAARLQISMCQKKAKEHNERDRRIYANMFKKFAE ::.: .:.:: :..::.:::.. :.::::. :...::.. ... :....:::::...:: NP_002 EAHLAVNDFELARADFQKVLQLYPNNKAAKTQLAVCQQRIRRQLAREKKLYANMFERLAE 370 380 390 400 410 420 420 430 440 450 pF1KB8 QDAKEEANKAMGKKTS------EGVTNEKGTDSQAMEEEKPEGHV .. : .:. . : . . : .: :..::. : NP_002 EENKAKAEASSGDHPTDTEMKEEQKSNTAGSQSQVETEA 430 440 450 >>XP_011519231 (OMIM: 600611) PREDICTED: peptidyl-prolyl (414 aa) initn: 1615 init1: 1125 opt: 1616 Z-score: 1775.5 bits: 337.6 E(85289): 3.7e-92 Smith-Waterman score: 1616; 57.0% identity (81.8% similar) in 412 aa overlap (47-450:2-413) 20 30 40 50 60 70 pF1KB8 TVAEQGEDITSKKDRGVLKIVKRVGNGEETPMIGDKVYVHYKGKLSNGKKFDSSHDRNEP :::::.:.::: : : .: ::::: ::.. XP_011 MPMIGDRVFVHYTGWLLDGTKFDSSLDRKDK 10 20 30 80 90 100 110 120 130 pF1KB8 FVFSLGKGQVIKAWDIGVATMKKGEICHLLCKPEYAYGSAGSLPKIPSNATLFFEIELLD : :.::::.:::::::..:::: ::.::. :::::::::::: :::: :::: ::.::.. XP_011 FSFDLGKGEVIKAWDIAIATMKVGEVCHITCKPEYAYGSAGSPPKIPPNATLVFEVELFE 40 50 60 70 80 90 140 150 160 170 180 190 pF1KB8 FKGEDLFE--DGGIIRRTKRKGEGYSNPNEGATVEIHLEGRCGGRMFDCRDVAFTVGEGE :::::: : ::::::: . .::::..::::: ::. ::: ..:: :.. : .:::: XP_011 FKGEDLTEEEDGGIIRRIQTRGEGYAKPNEGAIVEVALEGYYKDKLFDQRELRFEIGEGE 100 110 120 130 140 150 200 210 220 230 240 250 pF1KB8 DHDIPIGIDKALEKMQREEQCILYLGPRYGFGEAGKPKFGIEPNAELIYEVTLKSFEKAK . :.: :...:...:.. :. :.:: : :.:: .:: :: : ::::: ::. :::::::: XP_011 NLDLPYGLERAIQRMEKGEHSIVYLKPSYAFGSVGKEKFQIPPNAELKYELHLKSFEKAK 160 170 180 190 200 210 260 270 280 290 300 310 pF1KB8 ESWEMDTKEKLEQAAIVKEKGTVYFKGGKYMQAVIQYGKIVSWLEMEYGLSEKESKASES :::::...:::::..::::.:::::: ::: ::..:: :::::::.: ..:..:.. ... XP_011 ESWEMNSEEKLEQSTIVKERGTVYFKEGKYKQALLQYKKIVSWLEYESSFSNEEAQKAQA 220 230 240 250 260 270 320 330 340 350 360 370 pF1KB8 FLLAAFLNLAMCYLKLREYTKAVECCDKALGLDSANEKGLYRRGEAQLLMNEFESAKGDF . ::. ::::::.:::. .. :.: :.::: ::: :::::.:::::.: .:.:: :..:: XP_011 LRLASHLNLAMCHLKLQAFSAAIESCNKALELDSNNEKGLFRRGEAHLAVNDFELARADF 280 290 300 310 320 330 380 390 400 410 420 430 pF1KB8 EKVLEVNPQNKAARLQISMCQKKAKEHNERDRRIYANMFKKFAEQDAKEEANKAMGKKTS .:::.. :.::::. :...::.. ... :....:::::...::.. : .:. . : . . XP_011 QKVLQLYPNNKAAKTQLAVCQQRIRRQLAREKKLYANMFERLAEEENKAKAEASSGDHPT 340 350 360 370 380 390 440 450 pF1KB8 ------EGVTNEKGTDSQAMEEEKPEGHV : .: :..::. : XP_011 DTEMKEEQKSNTAGSQSQVETEA 400 410 >>NP_001139249 (OMIM: 602623,608516) peptidyl-prolyl cis (268 aa) initn: 1501 init1: 1501 opt: 1501 Z-score: 1652.3 bits: 314.2 E(85289): 2.7e-85 Smith-Waterman score: 1501; 100.0% identity (100.0% similar) in 222 aa overlap (1-222:1-222) 10 20 30 40 50 60 pF1KB8 MTTDEGAKNNEESPTATVAEQGEDITSKKDRGVLKIVKRVGNGEETPMIGDKVYVHYKGK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MTTDEGAKNNEESPTATVAEQGEDITSKKDRGVLKIVKRVGNGEETPMIGDKVYVHYKGK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 LSNGKKFDSSHDRNEPFVFSLGKGQVIKAWDIGVATMKKGEICHLLCKPEYAYGSAGSLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LSNGKKFDSSHDRNEPFVFSLGKGQVIKAWDIGVATMKKGEICHLLCKPEYAYGSAGSLP 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 KIPSNATLFFEIELLDFKGEDLFEDGGIIRRTKRKGEGYSNPNEGATVEIHLEGRCGGRM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KIPSNATLFFEIELLDFKGEDLFEDGGIIRRTKRKGEGYSNPNEGATVEIHLEGRCGGRM 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 FDCRDVAFTVGEGEDHDIPIGIDKALEKMQREEQCILYLGPRYGFGEAGKPKFGIEPNAE :::::::::::::::::::::::::::::::::::::::::: NP_001 FDCRDVAFTVGEGEDHDIPIGIDKALEKMQREEQCILYLGPRPKNPGRWIPKKNWSRLPL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 LIYEVTLKSFEKAKESWEMDTKEKLEQAAIVKEKGTVYFKGGKYMQAVIQYGKIVSWLEM NP_001 SKRREPYTSRCVSPYAILSISKNLFKCW 250 260 >>NP_004107 (OMIM: 600620) peptidyl-prolyl cis-trans iso (108 aa) initn: 325 init1: 325 opt: 325 Z-score: 370.8 bits: 75.8 E(85289): 6.5e-14 Smith-Waterman score: 325; 50.0% identity (74.5% similar) in 98 aa overlap (41-138:11-108) 20 30 40 50 60 70 pF1KB8 EESPTATVAEQGEDITSKKDRGVLKIVKRVGNGEETPMIGDKVYVHYKGKLSNGKKFDSS :.:. : :. ::: : :.:::::::: NP_004 MGVEIETISPGDGRTFPKKGQTCVVHYTGMLQNGKKFDSS 10 20 30 40 80 90 100 110 120 130 pF1KB8 HDRNEPFVFSLGKGQVIKAWDIGVATMKKGEICHLLCKPEYAYGSAGSLPKIPSNATLFF .:::.:: : .:: .:::... :.: :. :. .: : :. :::..: :: ::::.: NP_004 RDRNKPFKFRIGKQEVIKGFEEGAAQMSLGQRAKLTCTPDVAYGATGHPGVIPPNATLIF 50 60 70 80 90 100 140 150 160 170 180 190 pF1KB8 EIELLDFKGEDLFEDGGIIRRTKRKGEGYSNPNEGATVEIHLEGRCGGRMFDCRDVAFTV ..:::... NP_004 DVELLNLE >>NP_000792 (OMIM: 186945) peptidyl-prolyl cis-trans iso (108 aa) initn: 321 init1: 321 opt: 321 Z-score: 366.4 bits: 75.0 E(85289): 1.1e-13 Smith-Waterman score: 321; 50.0% identity (72.4% similar) in 98 aa overlap (41-138:11-108) 20 30 40 50 60 70 pF1KB8 EESPTATVAEQGEDITSKKDRGVLKIVKRVGNGEETPMIGDKVYVHYKGKLSNGKKFDSS :.:. : :. ::: : : .::::::: NP_000 MGVQVETISPGDGRTFPKRGQTCVVHYTGMLEDGKKFDSS 10 20 30 40 80 90 100 110 120 130 pF1KB8 HDRNEPFVFSLGKGQVIKAWDIGVATMKKGEICHLLCKPEYAYGSAGSLPKIPSNATLFF .:::.:: : ::: .::..:. ::: :. :. .: .:.::::..: :: .::: : NP_000 RDRNKPFKFMLGKQEVIRGWEEGVAQMSVGQRAKLTISPDYAYGATGHPGIIPPHATLVF 50 60 70 80 90 100 140 150 160 170 180 190 pF1KB8 EIELLDFKGEDLFEDGGIIRRTKRKGEGYSNPNEGATVEIHLEGRCGGRMFDCRDVAFTV ..::: .. NP_000 DVELLKLE >>NP_463460 (OMIM: 186945) peptidyl-prolyl cis-trans iso (108 aa) initn: 321 init1: 321 opt: 321 Z-score: 366.4 bits: 75.0 E(85289): 1.1e-13 Smith-Waterman score: 321; 50.0% identity (72.4% similar) in 98 aa overlap (41-138:11-108) 20 30 40 50 60 70 pF1KB8 EESPTATVAEQGEDITSKKDRGVLKIVKRVGNGEETPMIGDKVYVHYKGKLSNGKKFDSS :.:. : :. ::: : : .::::::: NP_463 MGVQVETISPGDGRTFPKRGQTCVVHYTGMLEDGKKFDSS 10 20 30 40 80 90 100 110 120 130 pF1KB8 HDRNEPFVFSLGKGQVIKAWDIGVATMKKGEICHLLCKPEYAYGSAGSLPKIPSNATLFF .:::.:: : ::: .::..:. ::: :. :. .: .:.::::..: :: .::: : NP_463 RDRNKPFKFMLGKQEVIRGWEEGVAQMSVGQRAKLTISPDYAYGATGHPGIIPPHATLVF 50 60 70 80 90 100 140 150 160 170 180 190 pF1KB8 EIELLDFKGEDLFEDGGIIRRTKRKGEGYSNPNEGATVEIHLEGRCGGRMFDCRDVAFTV ..::: .. NP_463 DVELLKLE >>XP_005273905 (OMIM: 186946) PREDICTED: peptidyl-prolyl (142 aa) initn: 318 init1: 318 opt: 318 Z-score: 361.4 bits: 74.4 E(85289): 2.2e-13 Smith-Waterman score: 318; 51.0% identity (70.0% similar) in 100 aa overlap (36-135:35-134) 10 20 30 40 50 60 pF1KB8 GAKNNEESPTATVAEQGEDITSKKDRGVLKIVKRVGNGEETPMIGDKVYVHYKGKLSNGK . ::: . :: ...:: ::: .: XP_005 WFRVLTVLSICLSAVATATGAEGKRKLQIGVKKRVDHCPIKSRKGDVLHMHYTGKLEDGT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 KFDSSHDRNEPFVFSLGKGQVIKAWDIGVATMKKGEICHLLCKPEYAYGSAGSLPKIPSN .:::: .:.::::::: :::::.:: :. : .:: .:. : .:: :. ::::.. XP_005 EFDSSLPQNQPFVFSLGTGQVIKGWDQGLLGMCEGEKRKLVIPSELGYGERGAPPKIPGG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 ATLFFEIELLDFKGEDLFEDGGIIRRTKRKGEGYSNPNEGATVEIHLEGRCGGRMFDCRD ::: ::.::: XP_005 ATLVFEVELLKIERRTEL 130 140 457 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 12:01:29 2016 done: Fri Nov 4 12:01:31 2016 Total Scan time: 8.830 Total Display time: 0.020 Function used was FASTA [36.3.4 Apr, 2011]