FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB8356, 381 aa 1>>>pF1KB8356 381 - 381 aa - 381 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 7.8181+/-0.000336; mu= 7.1644+/- 0.021 mean_var=161.5413+/-32.335, 0's: 0 Z-trim(120.6): 2 B-trim: 1273 in 1/56 Lambda= 0.100910 statistics sampled from 35961 (35963) to 35961 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.758), E-opt: 0.2 (0.422), width: 16 Scan time: 7.890 The best scores are: opt bits E(85289) NP_631905 (OMIM: 609747) actin-binding Rho-activat ( 381) 2611 391.5 1.7e-108 >>NP_631905 (OMIM: 609747) actin-binding Rho-activating (381 aa) initn: 2611 init1: 2611 opt: 2611 Z-score: 2068.8 bits: 391.5 E(85289): 1.7e-108 Smith-Waterman score: 2611; 100.0% identity (100.0% similar) in 381 aa overlap (1-381:1-381) 10 20 30 40 50 60 pF1KB8 MAPGEKESGEGPAKSALRKIRTATLVISLARGWQQWANENSIRQAQEPTGWLPGGTQDSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_631 MAPGEKESGEGPAKSALRKIRTATLVISLARGWQQWANENSIRQAQEPTGWLPGGTQDSP 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 QAPKPITPPTSHQKAQSAPKSPPRLPEGHGDGQSSEKAPEVSHIKKKEVSKTVVSKTYER :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_631 QAPKPITPPTSHQKAQSAPKSPPRLPEGHGDGQSSEKAPEVSHIKKKEVSKTVVSKTYER 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 GGDVSHLSHRYERDAGVLEPGQPENDIDRILHSHGSPTRRRKCANLVSELTKGWRVMEQE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_631 GGDVSHLSHRYERDAGVLEPGQPENDIDRILHSHGSPTRRRKCANLVSELTKGWRVMEQE 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 EPTWRSDSVDTEDSGYGGEAEERPEQDGVQVAVVRIKRPLPSQVNRFTEKLNCKAQQKYS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_631 EPTWRSDSVDTEDSGYGGEAEERPEQDGVQVAVVRIKRPLPSQVNRFTEKLNCKAQQKYS 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 PVGNLKGRWQQWADEHIQSQKLNPFSEEFDYELAMSTRLHKGDEGYGRPKEGTKTAERAK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_631 PVGNLKGRWQQWADEHIQSQKLNPFSEEFDYELAMSTRLHKGDEGYGRPKEGTKTAERAK 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 RAEEHIYREMMDMCFIICTMARHRRDGKIQVTFGDLFDRYVRISDKVVGILMRARKHGLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_631 RAEEHIYREMMDMCFIICTMARHRRDGKIQVTFGDLFDRYVRISDKVVGILMRARKHGLV 310 320 330 340 350 360 370 380 pF1KB8 DFEGEMLWQGRDDHVVITLLK ::::::::::::::::::::: NP_631 DFEGEMLWQGRDDHVVITLLK 370 380 381 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 12:03:33 2016 done: Fri Nov 4 12:03:34 2016 Total Scan time: 7.890 Total Display time: -0.030 Function used was FASTA [36.3.4 Apr, 2011]