FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB8361, 144 aa 1>>>pF1KB8361 144 - 144 aa - 144 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 4.5326+/-0.000789; mu= 16.6766+/- 0.048 mean_var=85.7676+/-16.495, 0's: 0 Z-trim(110.4): 26 B-trim: 51 in 1/49 Lambda= 0.138488 statistics sampled from 11576 (11593) to 11576 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.73), E-opt: 0.2 (0.356), width: 16 Scan time: 1.690 The best scores are: opt bits E(32554) CCDS201.1 PLA2G2A gene_id:5320|Hs108|chr1 ( 144) 1026 213.8 2.9e-56 CCDS203.1 PLA2G2D gene_id:26279|Hs108|chr1 ( 145) 520 112.7 7.9e-26 CCDS200.1 PLA2G2E gene_id:30814|Hs108|chr1 ( 142) 487 106.1 7.5e-24 CCDS202.1 PLA2G5 gene_id:5322|Hs108|chr1 ( 138) 462 101.1 2.4e-22 CCDS204.2 PLA2G2F gene_id:64600|Hs108|chr1 ( 211) 414 91.8 2.4e-19 CCDS10555.1 PLA2G10 gene_id:8399|Hs108|chr16 ( 165) 363 81.4 2.4e-16 CCDS9195.1 PLA2G1B gene_id:5319|Hs108|chr12 ( 148) 338 76.4 7.1e-15 >>CCDS201.1 PLA2G2A gene_id:5320|Hs108|chr1 (144 aa) initn: 1026 init1: 1026 opt: 1026 Z-score: 1123.6 bits: 213.8 E(32554): 2.9e-56 Smith-Waterman score: 1026; 100.0% identity (100.0% similar) in 144 aa overlap (1-144:1-144) 10 20 30 40 50 60 pF1KB8 MKTLLLLAVIMIFGLLQAHGNLVNFHRMIKLTTGKEAALSYGFYGCHCGVGGRGSPKDAT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS20 MKTLLLLAVIMIFGLLQAHGNLVNFHRMIKLTTGKEAALSYGFYGCHCGVGGRGSPKDAT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 DRCCVTHDCCYKRLEKRGCGTKFLSYKFSNSGSRITCAKQDSCRSQLCECDKAAATCFAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS20 DRCCVTHDCCYKRLEKRGCGTKFLSYKFSNSGSRITCAKQDSCRSQLCECDKAAATCFAR 70 80 90 100 110 120 130 140 pF1KB8 NKTTYNKKYQYYSNKHCRGSTPRC :::::::::::::::::::::::: CCDS20 NKTTYNKKYQYYSNKHCRGSTPRC 130 140 >>CCDS203.1 PLA2G2D gene_id:26279|Hs108|chr1 (145 aa) initn: 495 init1: 329 opt: 520 Z-score: 577.2 bits: 112.7 E(32554): 7.9e-26 Smith-Waterman score: 520; 46.9% identity (73.1% similar) in 145 aa overlap (1-144:1-145) 10 20 30 40 50 60 pF1KB8 MKTLLLLAVIMIFGLLQAHGNLVNFHRMIKLTTGKEAALSYGFYGCHCGVGGRGSPKDAT :. :: ..... :.. .:...:...:.: .::: ::: ::::::.::::.::::: CCDS20 MELALLCGLVVMAGVIPIQGGILNLNKMVKQVTGKMPILSYWPYGCHCGLGGRGQPKDAT 10 20 30 40 50 60 70 80 90 100 110 pF1KB8 DRCCVTHDCCYKRLEKRGCGTKFLSYKFSNSGSRITCAKQDS-CRSQLCECDKAAATCFA : :: :::::: .:. .::. :... : . : :. . : :..::: ::: .: :. CCDS20 DWCCQTHDCCYDHLKTQGCSIYKDYYRYNFSQGNIHCSDKGSWCEQQLCACDKEVAFCLK 70 80 90 100 110 120 120 130 140 pF1KB8 RNKTTYNKKYQYYSNKHCRGSTPRC :: ::.:. ..: ::::.:: : CCDS20 RNLDTYQKRLRFYWRPHCRGQTPGC 130 140 >>CCDS200.1 PLA2G2E gene_id:30814|Hs108|chr1 (142 aa) initn: 500 init1: 440 opt: 487 Z-score: 541.6 bits: 106.1 E(32554): 7.5e-24 Smith-Waterman score: 487; 53.6% identity (67.4% similar) in 138 aa overlap (9-144:6-142) 10 20 30 40 50 pF1KB8 MKTLLLLAVIMIFGLLQA--HGNLVNFHRMIKLTTGKEAALSYGFYGCHCGVGGRGSPKD :.... :: : ::::.: ::. ::: .::.:. :::.::.:: : : CCDS20 MKSPHVLVFLCLLVALVTGNLVQFGVMIEKMTGK-SALQYNDYGCYCGIGGSHWPVD 10 20 30 40 50 60 70 80 90 100 110 pF1KB8 ATDRCCVTHDCCYKRLEKRGCGTKFLSYKFSNSGSRITCAKQDSCRSQLCECDKAAATCF :: :: .::::: :::: :: :. .: :: : : :: . .:. ::::: :: :: CCDS20 QTDWCCHAHDCCYGRLEKLGCEPKLEKYLFSVSERGIFCAGRTTCQRLTCECDKRAALCF 60 70 80 90 100 110 120 130 140 pF1KB8 ARNKTTYNKKYQYYSNKHCRGSTPRC :: :::.:: .: :: : : :: : CCDS20 RRNLGTYNRKYAHYPNKLCTGPTPPC 120 130 140 >>CCDS202.1 PLA2G5 gene_id:5322|Hs108|chr1 (138 aa) initn: 469 init1: 455 opt: 462 Z-score: 514.8 bits: 101.1 E(32554): 2.4e-22 Smith-Waterman score: 462; 45.3% identity (70.8% similar) in 137 aa overlap (1-137:1-137) 10 20 30 40 50 60 pF1KB8 MKTLLLLAVIMIFGLLQAHGNLVNFHRMIKLTTGKEAALSYGFYGCHCGVGGRGSPKDAT :: :: :: .. .. ..:.:.... ::. .:::.: .::::::.:: ::::.:::.: CCDS20 MKGLLPLAWFLACSVPAVQGGLLDLKSMIEKVTGKNALTNYGFYGCYCGWGGRGTPKDGT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 DRCCVTHDCCYKRLEKRGCGTKFLSYKFSNSGSRITCAKQDSCRSQLCECDKAAATCFAR : :: .:: :: :::..::. . :::. . . .:: :. .:: ::. . :. : CCDS20 DWCCWAHDHCYGRLEEKGCNIRTQSYKYRFAWGVVTCEPGPFCHVNLCACDRKLVYCLKR 70 80 90 100 110 120 130 140 pF1KB8 NKTTYNKKYQYYSNKHCRGSTPRC : .:: .:::. : : CCDS20 NLRSYNPQYQYFPNILCS 130 >>CCDS204.2 PLA2G2F gene_id:64600|Hs108|chr1 (211 aa) initn: 349 init1: 296 opt: 414 Z-score: 460.9 bits: 91.8 E(32554): 2.4e-19 Smith-Waterman score: 414; 38.8% identity (67.3% similar) in 147 aa overlap (1-144:44-188) 10 20 30 pF1KB8 MKTLLLLAVIMIFGLLQAHGNLVNFHRMIK :: .. .:.. : :::.:.:.. :.. CCDS20 KKVLDRCFSGWRGPRFGASCPSRTSRSSLGMKKFFTVAILAGSVLSTAHGSLLNLKAMVE 20 30 40 50 60 70 40 50 60 70 80 pF1KB8 LTTGKEAALSYGFYGCHCGVGGRGSPKDATDRCCVTHDCCYKRLEKRGCGTKFLSYKFS- .::. : ::. :::.::.::::.::: .: :: .:::::..: .:: : . CCDS20 AVTGRSAILSFVGYGCYCGLGGRGQPKDEVDWCCHAHDCCYQELFDQGCHPYVDHYDHTI 80 90 100 110 120 130 90 100 110 120 130 140 pF1KB8 NSGSRITCA--KQDSCRSQLCECDKAAATCFARNKTTYNKKYQYYSNKHCRGSTPRC .....:.:. .. : .: : ::: . :. . :: ..:. . : .:.: :: : CCDS20 ENNTEIVCSDLNKTECDKQTCMCDKNMVLCLMNQ--TYREEYRGFLNVYCQGPTPNCSIY 140 150 160 170 180 190 CCDS20 EPPPEEVTCSHQSPAPPAPP 200 210 >>CCDS10555.1 PLA2G10 gene_id:8399|Hs108|chr16 (165 aa) initn: 336 init1: 211 opt: 363 Z-score: 407.0 bits: 81.4 E(32554): 2.4e-16 Smith-Waterman score: 371; 35.7% identity (64.9% similar) in 154 aa overlap (4-144:13-164) 10 20 30 pF1KB8 MKTLLLLAVIMIFGLLQAHGN-----LVNFHR--MIKLT-----TGKEAAL :::: .... :: . :. .. :: ...:. .: .. . CCDS10 MGPLPVCLPIMLLLLLPSLLLLLLLPGPGSGEASRILRVHRRGILELAGTVGCVGPRTPI 10 20 30 40 50 60 40 50 60 70 80 90 pF1KB8 SYGFYGCHCGVGGRGSPKDATDRCCVTHDCCYKRLEKRGCGTKFLSYKFSNSGSRITCAK .: ::: ::.::.:.:.:: : :: ::::: : :. ::. : :... .. . :. CCDS10 AYMKYGCFCGLGGHGQPRDAIDWCCHGHDCCYTRAEEAGCSPKTERYSWQCVNQSVLCGP 70 80 90 100 110 120 100 110 120 130 140 pF1KB8 -QDSCRSQLCECDKAAATCFARNKTTYNKKYQYYSNKHCRGSTPRC ...:. ::.::. :.:.: .: :: :: .: . :. ..:.: CCDS10 AENKCQELLCKCDQEIANCLA--QTEYNLKYLFYPQFLCEPDSPKCD 130 140 150 160 >>CCDS9195.1 PLA2G1B gene_id:5319|Hs108|chr12 (148 aa) initn: 316 init1: 197 opt: 338 Z-score: 380.6 bits: 76.4 E(32554): 7.1e-15 Smith-Waterman score: 338; 38.8% identity (67.1% similar) in 152 aa overlap (1-138:1-147) 10 20 30 40 50 pF1KB8 MKTLLLLAVIMIFGLLQAHGN---LVNFHRMIK-LTTGKEAALSYGFYGCHCGVGGRGSP :: ::.:::.. . .. . . .:..::: . :.. : :. :::.::.:: :.: CCDS91 MK-LLVLAVLLTVAAADSGISPRAVWQFRKMIKCVIPGSDPFLEYNNYGCYCGLGGSGTP 10 20 30 40 50 60 70 80 90 100 pF1KB8 KDATDRCCVTHDCCYKRLEK-RGCGTKFL-------SYKFSNSGSRITCAKQDS-CRSQL : :.:: ::: :: . .: .: ::: .:..: ::: :::..... :.. . CCDS91 VDELDKCCQTHDNCYDQAKKLDSC--KFLLDNPYTHTYSYSCSGSAITCSSKNKECEAFI 60 70 80 90 100 110 110 120 130 140 pF1KB8 CECDKAAATCFARNKTTYNKKYQYY-SNKHCRGSTPRC :.::. :: :: .:. ::: .. ..:.:. CCDS91 CNCDRNAAICF--SKAPYNKAHKNLDTKKYCQS 120 130 140 144 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 12:08:18 2016 done: Fri Nov 4 12:08:18 2016 Total Scan time: 1.690 Total Display time: -0.030 Function used was FASTA [36.3.4 Apr, 2011]