FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB8361, 144 aa 1>>>pF1KB8361 144 - 144 aa - 144 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 4.7700+/-0.000331; mu= 15.1641+/- 0.021 mean_var=82.8550+/-16.553, 0's: 0 Z-trim(116.8): 29 B-trim: 144 in 2/53 Lambda= 0.140901 statistics sampled from 28177 (28211) to 28177 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.705), E-opt: 0.2 (0.331), width: 16 Scan time: 4.860 The best scores are: opt bits E(85289) NP_000291 (OMIM: 172411) phospholipase A2, membran ( 144) 1026 217.4 6.2e-57 NP_001155201 (OMIM: 172411) phospholipase A2, memb ( 144) 1026 217.4 6.2e-57 NP_001155200 (OMIM: 172411) phospholipase A2, memb ( 144) 1026 217.4 6.2e-57 NP_001155199 (OMIM: 172411) phospholipase A2, memb ( 144) 1026 217.4 6.2e-57 NP_036532 (OMIM: 605630) group IID secretory phosp ( 145) 520 114.6 5.8e-26 XP_011539893 (OMIM: 228980,601192) PREDICTED: calc ( 138) 462 102.8 2e-22 XP_011539889 (OMIM: 228980,601192) PREDICTED: calc ( 138) 462 102.8 2e-22 NP_000920 (OMIM: 228980,601192) calcium-dependent ( 138) 462 102.8 2e-22 XP_011539892 (OMIM: 228980,601192) PREDICTED: calc ( 138) 462 102.8 2e-22 XP_011539891 (OMIM: 228980,601192) PREDICTED: calc ( 138) 462 102.8 2e-22 XP_005245950 (OMIM: 228980,601192) PREDICTED: calc ( 138) 462 102.8 2e-22 XP_011539894 (OMIM: 228980,601192) PREDICTED: calc ( 138) 462 102.8 2e-22 XP_011539890 (OMIM: 228980,601192) PREDICTED: calc ( 138) 462 102.8 2e-22 XP_005245948 (OMIM: 228980,601192) PREDICTED: calc ( 169) 462 102.9 2.3e-22 XP_005245949 (OMIM: 228980,601192) PREDICTED: calc ( 169) 462 102.9 2.3e-22 XP_011539888 (OMIM: 228980,601192) PREDICTED: calc ( 169) 462 102.9 2.3e-22 XP_011540258 (OMIM: 616793) PREDICTED: group IIF s ( 211) 414 93.2 2.3e-19 NP_073730 (OMIM: 616793) group IIF secretory phosp ( 211) 414 93.2 2.3e-19 NP_003552 (OMIM: 603603) group 10 secretory phosph ( 165) 363 82.7 2.5e-16 NP_000919 (OMIM: 172410) phospholipase A2 precurso ( 148) 338 77.6 8e-15 XP_011540257 (OMIM: 616793) PREDICTED: group IIF s ( 219) 303 70.7 1.4e-12 NP_001073868 (OMIM: 601658) otoconin-90 precursor ( 477) 272 64.7 1.9e-10 XP_011520997 (OMIM: 603603) PREDICTED: group 10 se ( 133) 239 57.4 8.5e-09 XP_011521000 (OMIM: 603603) PREDICTED: group 10 se ( 120) 238 57.2 9.1e-09 XP_011520999 (OMIM: 603603) PREDICTED: group 10 se ( 124) 238 57.2 9.4e-09 XP_011520998 (OMIM: 603603) PREDICTED: group 10 se ( 131) 238 57.2 9.7e-09 NP_001258743 (OMIM: 605630) group IID secretory ph ( 62) 227 54.6 2.8e-08 >>NP_000291 (OMIM: 172411) phospholipase A2, membrane as (144 aa) initn: 1026 init1: 1026 opt: 1026 Z-score: 1143.1 bits: 217.4 E(85289): 6.2e-57 Smith-Waterman score: 1026; 100.0% identity (100.0% similar) in 144 aa overlap (1-144:1-144) 10 20 30 40 50 60 pF1KB8 MKTLLLLAVIMIFGLLQAHGNLVNFHRMIKLTTGKEAALSYGFYGCHCGVGGRGSPKDAT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 MKTLLLLAVIMIFGLLQAHGNLVNFHRMIKLTTGKEAALSYGFYGCHCGVGGRGSPKDAT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 DRCCVTHDCCYKRLEKRGCGTKFLSYKFSNSGSRITCAKQDSCRSQLCECDKAAATCFAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 DRCCVTHDCCYKRLEKRGCGTKFLSYKFSNSGSRITCAKQDSCRSQLCECDKAAATCFAR 70 80 90 100 110 120 130 140 pF1KB8 NKTTYNKKYQYYSNKHCRGSTPRC :::::::::::::::::::::::: NP_000 NKTTYNKKYQYYSNKHCRGSTPRC 130 140 >>NP_001155201 (OMIM: 172411) phospholipase A2, membrane (144 aa) initn: 1026 init1: 1026 opt: 1026 Z-score: 1143.1 bits: 217.4 E(85289): 6.2e-57 Smith-Waterman score: 1026; 100.0% identity (100.0% similar) in 144 aa overlap (1-144:1-144) 10 20 30 40 50 60 pF1KB8 MKTLLLLAVIMIFGLLQAHGNLVNFHRMIKLTTGKEAALSYGFYGCHCGVGGRGSPKDAT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MKTLLLLAVIMIFGLLQAHGNLVNFHRMIKLTTGKEAALSYGFYGCHCGVGGRGSPKDAT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 DRCCVTHDCCYKRLEKRGCGTKFLSYKFSNSGSRITCAKQDSCRSQLCECDKAAATCFAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DRCCVTHDCCYKRLEKRGCGTKFLSYKFSNSGSRITCAKQDSCRSQLCECDKAAATCFAR 70 80 90 100 110 120 130 140 pF1KB8 NKTTYNKKYQYYSNKHCRGSTPRC :::::::::::::::::::::::: NP_001 NKTTYNKKYQYYSNKHCRGSTPRC 130 140 >>NP_001155200 (OMIM: 172411) phospholipase A2, membrane (144 aa) initn: 1026 init1: 1026 opt: 1026 Z-score: 1143.1 bits: 217.4 E(85289): 6.2e-57 Smith-Waterman score: 1026; 100.0% identity (100.0% similar) in 144 aa overlap (1-144:1-144) 10 20 30 40 50 60 pF1KB8 MKTLLLLAVIMIFGLLQAHGNLVNFHRMIKLTTGKEAALSYGFYGCHCGVGGRGSPKDAT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MKTLLLLAVIMIFGLLQAHGNLVNFHRMIKLTTGKEAALSYGFYGCHCGVGGRGSPKDAT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 DRCCVTHDCCYKRLEKRGCGTKFLSYKFSNSGSRITCAKQDSCRSQLCECDKAAATCFAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DRCCVTHDCCYKRLEKRGCGTKFLSYKFSNSGSRITCAKQDSCRSQLCECDKAAATCFAR 70 80 90 100 110 120 130 140 pF1KB8 NKTTYNKKYQYYSNKHCRGSTPRC :::::::::::::::::::::::: NP_001 NKTTYNKKYQYYSNKHCRGSTPRC 130 140 >>NP_001155199 (OMIM: 172411) phospholipase A2, membrane (144 aa) initn: 1026 init1: 1026 opt: 1026 Z-score: 1143.1 bits: 217.4 E(85289): 6.2e-57 Smith-Waterman score: 1026; 100.0% identity (100.0% similar) in 144 aa overlap (1-144:1-144) 10 20 30 40 50 60 pF1KB8 MKTLLLLAVIMIFGLLQAHGNLVNFHRMIKLTTGKEAALSYGFYGCHCGVGGRGSPKDAT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MKTLLLLAVIMIFGLLQAHGNLVNFHRMIKLTTGKEAALSYGFYGCHCGVGGRGSPKDAT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 DRCCVTHDCCYKRLEKRGCGTKFLSYKFSNSGSRITCAKQDSCRSQLCECDKAAATCFAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DRCCVTHDCCYKRLEKRGCGTKFLSYKFSNSGSRITCAKQDSCRSQLCECDKAAATCFAR 70 80 90 100 110 120 130 140 pF1KB8 NKTTYNKKYQYYSNKHCRGSTPRC :::::::::::::::::::::::: NP_001 NKTTYNKKYQYYSNKHCRGSTPRC 130 140 >>NP_036532 (OMIM: 605630) group IID secretory phospholi (145 aa) initn: 495 init1: 329 opt: 520 Z-score: 587.2 bits: 114.6 E(85289): 5.8e-26 Smith-Waterman score: 520; 46.9% identity (73.1% similar) in 145 aa overlap (1-144:1-145) 10 20 30 40 50 60 pF1KB8 MKTLLLLAVIMIFGLLQAHGNLVNFHRMIKLTTGKEAALSYGFYGCHCGVGGRGSPKDAT :. :: ..... :.. .:...:...:.: .::: ::: ::::::.::::.::::: NP_036 MELALLCGLVVMAGVIPIQGGILNLNKMVKQVTGKMPILSYWPYGCHCGLGGRGQPKDAT 10 20 30 40 50 60 70 80 90 100 110 pF1KB8 DRCCVTHDCCYKRLEKRGCGTKFLSYKFSNSGSRITCAKQDS-CRSQLCECDKAAATCFA : :: :::::: .:. .::. :... : . : :. . : :..::: ::: .: :. NP_036 DWCCQTHDCCYDHLKTQGCSIYKDYYRYNFSQGNIHCSDKGSWCEQQLCACDKEVAFCLK 70 80 90 100 110 120 120 130 140 pF1KB8 RNKTTYNKKYQYYSNKHCRGSTPRC :: ::.:. ..: ::::.:: : NP_036 RNLDTYQKRLRFYWRPHCRGQTPGC 130 140 >>XP_011539893 (OMIM: 228980,601192) PREDICTED: calcium- (138 aa) initn: 469 init1: 455 opt: 462 Z-score: 523.7 bits: 102.8 E(85289): 2e-22 Smith-Waterman score: 462; 45.3% identity (70.8% similar) in 137 aa overlap (1-137:1-137) 10 20 30 40 50 60 pF1KB8 MKTLLLLAVIMIFGLLQAHGNLVNFHRMIKLTTGKEAALSYGFYGCHCGVGGRGSPKDAT :: :: :: .. .. ..:.:.... ::. .:::.: .::::::.:: ::::.:::.: XP_011 MKGLLPLAWFLACSVPAVQGGLLDLKSMIEKVTGKNALTNYGFYGCYCGWGGRGTPKDGT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 DRCCVTHDCCYKRLEKRGCGTKFLSYKFSNSGSRITCAKQDSCRSQLCECDKAAATCFAR : :: .:: :: :::..::. . :::. . . .:: :. .:: ::. . :. : XP_011 DWCCWAHDHCYGRLEEKGCNIRTQSYKYRFAWGVVTCEPGPFCHVNLCACDRKLVYCLKR 70 80 90 100 110 120 130 140 pF1KB8 NKTTYNKKYQYYSNKHCRGSTPRC : .:: .:::. : : XP_011 NLRSYNPQYQYFPNILCS 130 >>XP_011539889 (OMIM: 228980,601192) PREDICTED: calcium- (138 aa) initn: 469 init1: 455 opt: 462 Z-score: 523.7 bits: 102.8 E(85289): 2e-22 Smith-Waterman score: 462; 45.3% identity (70.8% similar) in 137 aa overlap (1-137:1-137) 10 20 30 40 50 60 pF1KB8 MKTLLLLAVIMIFGLLQAHGNLVNFHRMIKLTTGKEAALSYGFYGCHCGVGGRGSPKDAT :: :: :: .. .. ..:.:.... ::. .:::.: .::::::.:: ::::.:::.: XP_011 MKGLLPLAWFLACSVPAVQGGLLDLKSMIEKVTGKNALTNYGFYGCYCGWGGRGTPKDGT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 DRCCVTHDCCYKRLEKRGCGTKFLSYKFSNSGSRITCAKQDSCRSQLCECDKAAATCFAR : :: .:: :: :::..::. . :::. . . .:: :. .:: ::. . :. : XP_011 DWCCWAHDHCYGRLEEKGCNIRTQSYKYRFAWGVVTCEPGPFCHVNLCACDRKLVYCLKR 70 80 90 100 110 120 130 140 pF1KB8 NKTTYNKKYQYYSNKHCRGSTPRC : .:: .:::. : : XP_011 NLRSYNPQYQYFPNILCS 130 >>NP_000920 (OMIM: 228980,601192) calcium-dependent phos (138 aa) initn: 469 init1: 455 opt: 462 Z-score: 523.7 bits: 102.8 E(85289): 2e-22 Smith-Waterman score: 462; 45.3% identity (70.8% similar) in 137 aa overlap (1-137:1-137) 10 20 30 40 50 60 pF1KB8 MKTLLLLAVIMIFGLLQAHGNLVNFHRMIKLTTGKEAALSYGFYGCHCGVGGRGSPKDAT :: :: :: .. .. ..:.:.... ::. .:::.: .::::::.:: ::::.:::.: NP_000 MKGLLPLAWFLACSVPAVQGGLLDLKSMIEKVTGKNALTNYGFYGCYCGWGGRGTPKDGT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 DRCCVTHDCCYKRLEKRGCGTKFLSYKFSNSGSRITCAKQDSCRSQLCECDKAAATCFAR : :: .:: :: :::..::. . :::. . . .:: :. .:: ::. . :. : NP_000 DWCCWAHDHCYGRLEEKGCNIRTQSYKYRFAWGVVTCEPGPFCHVNLCACDRKLVYCLKR 70 80 90 100 110 120 130 140 pF1KB8 NKTTYNKKYQYYSNKHCRGSTPRC : .:: .:::. : : NP_000 NLRSYNPQYQYFPNILCS 130 >>XP_011539892 (OMIM: 228980,601192) PREDICTED: calcium- (138 aa) initn: 469 init1: 455 opt: 462 Z-score: 523.7 bits: 102.8 E(85289): 2e-22 Smith-Waterman score: 462; 45.3% identity (70.8% similar) in 137 aa overlap (1-137:1-137) 10 20 30 40 50 60 pF1KB8 MKTLLLLAVIMIFGLLQAHGNLVNFHRMIKLTTGKEAALSYGFYGCHCGVGGRGSPKDAT :: :: :: .. .. ..:.:.... ::. .:::.: .::::::.:: ::::.:::.: XP_011 MKGLLPLAWFLACSVPAVQGGLLDLKSMIEKVTGKNALTNYGFYGCYCGWGGRGTPKDGT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 DRCCVTHDCCYKRLEKRGCGTKFLSYKFSNSGSRITCAKQDSCRSQLCECDKAAATCFAR : :: .:: :: :::..::. . :::. . . .:: :. .:: ::. . :. : XP_011 DWCCWAHDHCYGRLEEKGCNIRTQSYKYRFAWGVVTCEPGPFCHVNLCACDRKLVYCLKR 70 80 90 100 110 120 130 140 pF1KB8 NKTTYNKKYQYYSNKHCRGSTPRC : .:: .:::. : : XP_011 NLRSYNPQYQYFPNILCS 130 >>XP_011539891 (OMIM: 228980,601192) PREDICTED: calcium- (138 aa) initn: 469 init1: 455 opt: 462 Z-score: 523.7 bits: 102.8 E(85289): 2e-22 Smith-Waterman score: 462; 45.3% identity (70.8% similar) in 137 aa overlap (1-137:1-137) 10 20 30 40 50 60 pF1KB8 MKTLLLLAVIMIFGLLQAHGNLVNFHRMIKLTTGKEAALSYGFYGCHCGVGGRGSPKDAT :: :: :: .. .. ..:.:.... ::. .:::.: .::::::.:: ::::.:::.: XP_011 MKGLLPLAWFLACSVPAVQGGLLDLKSMIEKVTGKNALTNYGFYGCYCGWGGRGTPKDGT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 DRCCVTHDCCYKRLEKRGCGTKFLSYKFSNSGSRITCAKQDSCRSQLCECDKAAATCFAR : :: .:: :: :::..::. . :::. . . .:: :. .:: ::. . :. : XP_011 DWCCWAHDHCYGRLEEKGCNIRTQSYKYRFAWGVVTCEPGPFCHVNLCACDRKLVYCLKR 70 80 90 100 110 120 130 140 pF1KB8 NKTTYNKKYQYYSNKHCRGSTPRC : .:: .:::. : : XP_011 NLRSYNPQYQYFPNILCS 130 144 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 12:08:19 2016 done: Fri Nov 4 12:08:19 2016 Total Scan time: 4.860 Total Display time: -0.020 Function used was FASTA [36.3.4 Apr, 2011]