FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB8367, 298 aa 1>>>pF1KB8367 298 - 298 aa - 298 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 7.1424+/-0.00112; mu= 6.3417+/- 0.066 mean_var=150.3507+/-29.560, 0's: 0 Z-trim(106.2): 138 B-trim: 2 in 1/51 Lambda= 0.104598 statistics sampled from 8714 (8873) to 8714 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.646), E-opt: 0.2 (0.273), width: 16 Scan time: 2.520 The best scores are: opt bits E(32554) CCDS42911.1 JAM2 gene_id:58494|Hs108|chr21 ( 298) 1936 304.2 7.7e-83 CCDS58787.1 JAM2 gene_id:58494|Hs108|chr21 ( 312) 1870 294.3 8e-80 CCDS58788.1 JAM2 gene_id:58494|Hs108|chr21 ( 262) 1431 227.9 6.1e-60 CCDS8494.2 JAM3 gene_id:83700|Hs108|chr11 ( 310) 642 108.9 4.8e-24 CCDS1213.1 F11R gene_id:50848|Hs108|chr1 ( 299) 563 97.0 1.8e-20 CCDS55799.1 JAM3 gene_id:83700|Hs108|chr11 ( 259) 456 80.8 1.2e-15 >>CCDS42911.1 JAM2 gene_id:58494|Hs108|chr21 (298 aa) initn: 1936 init1: 1936 opt: 1936 Z-score: 1600.7 bits: 304.2 E(32554): 7.7e-83 Smith-Waterman score: 1936; 100.0% identity (100.0% similar) in 298 aa overlap (1-298:1-298) 10 20 30 40 50 60 pF1KB8 MARRSRHRLLLLLLRYLVVALGYHKAYGFSAPKDQQVVTAVEYQEAILACKTPKKTVSSR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 MARRSRHRLLLLLLRYLVVALGYHKAYGFSAPKDQQVVTAVEYQEAILACKTPKKTVSSR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 LEWKKLGRSVSFVYYQQTLQGDFKNRAEMIDFNIRIKNVTRSDAGKYRCEVSAPSEQGQN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 LEWKKLGRSVSFVYYQQTLQGDFKNRAEMIDFNIRIKNVTRSDAGKYRCEVSAPSEQGQN 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 LEEDTVTLEVLVAPAVPSCEVPSSALSGTVVELRCQDKEGNPAPEYTWFKDGIRLLENPR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 LEEDTVTLEVLVAPAVPSCEVPSSALSGTVVELRCQDKEGNPAPEYTWFKDGIRLLENPR 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 LGSQSTNSSYTMNTKTGTLQFNTVSKLDTGEYSCEARNSVGYRRCPGKRMQVDDLNISGI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 LGSQSTNSSYTMNTKTGTLQFNTVSKLDTGEYSCEARNSVGYRRCPGKRMQVDDLNISGI 190 200 210 220 230 240 250 260 270 280 290 pF1KB8 IAAVVVVALVISVCGLGVCYAQRKGYFSKETSFQKSNSSSKATTMSENDFKHTKSFII :::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 IAAVVVVALVISVCGLGVCYAQRKGYFSKETSFQKSNSSSKATTMSENDFKHTKSFII 250 260 270 280 290 >>CCDS58787.1 JAM2 gene_id:58494|Hs108|chr21 (312 aa) initn: 1870 init1: 1870 opt: 1870 Z-score: 1546.6 bits: 294.3 E(32554): 8e-80 Smith-Waterman score: 1870; 100.0% identity (100.0% similar) in 288 aa overlap (1-288:1-288) 10 20 30 40 50 60 pF1KB8 MARRSRHRLLLLLLRYLVVALGYHKAYGFSAPKDQQVVTAVEYQEAILACKTPKKTVSSR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 MARRSRHRLLLLLLRYLVVALGYHKAYGFSAPKDQQVVTAVEYQEAILACKTPKKTVSSR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 LEWKKLGRSVSFVYYQQTLQGDFKNRAEMIDFNIRIKNVTRSDAGKYRCEVSAPSEQGQN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 LEWKKLGRSVSFVYYQQTLQGDFKNRAEMIDFNIRIKNVTRSDAGKYRCEVSAPSEQGQN 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 LEEDTVTLEVLVAPAVPSCEVPSSALSGTVVELRCQDKEGNPAPEYTWFKDGIRLLENPR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 LEEDTVTLEVLVAPAVPSCEVPSSALSGTVVELRCQDKEGNPAPEYTWFKDGIRLLENPR 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 LGSQSTNSSYTMNTKTGTLQFNTVSKLDTGEYSCEARNSVGYRRCPGKRMQVDDLNISGI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 LGSQSTNSSYTMNTKTGTLQFNTVSKLDTGEYSCEARNSVGYRRCPGKRMQVDDLNISGI 190 200 210 220 230 240 250 260 270 280 290 pF1KB8 IAAVVVVALVISVCGLGVCYAQRKGYFSKETSFQKSNSSSKATTMSENDFKHTKSFII :::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 IAAVVVVALVISVCGLGVCYAQRKGYFSKETSFQKSNSSSKATTMSENVQWLTPVIPALW 250 260 270 280 290 300 CCDS58 KAAAGGSRGQEF 310 >>CCDS58788.1 JAM2 gene_id:58494|Hs108|chr21 (262 aa) initn: 1431 init1: 1431 opt: 1431 Z-score: 1189.6 bits: 227.9 E(32554): 6.1e-60 Smith-Waterman score: 1622; 87.9% identity (87.9% similar) in 298 aa overlap (1-298:1-262) 10 20 30 40 50 60 pF1KB8 MARRSRHRLLLLLLRYLVVALGYHKAYGFSAPKDQQVVTAVEYQEAILACKTPKKTVSSR :::::::::::::::::::::::::::::::::::::::::::: CCDS58 MARRSRHRLLLLLLRYLVVALGYHKAYGFSAPKDQQVVTAVEYQ---------------- 10 20 30 40 70 80 90 100 110 120 pF1KB8 LEWKKLGRSVSFVYYQQTLQGDFKNRAEMIDFNIRIKNVTRSDAGKYRCEVSAPSEQGQN :::::::::::::::::::::::::::::::::::::::: CCDS58 --------------------GDFKNRAEMIDFNIRIKNVTRSDAGKYRCEVSAPSEQGQN 50 60 70 80 130 140 150 160 170 180 pF1KB8 LEEDTVTLEVLVAPAVPSCEVPSSALSGTVVELRCQDKEGNPAPEYTWFKDGIRLLENPR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 LEEDTVTLEVLVAPAVPSCEVPSSALSGTVVELRCQDKEGNPAPEYTWFKDGIRLLENPR 90 100 110 120 130 140 190 200 210 220 230 240 pF1KB8 LGSQSTNSSYTMNTKTGTLQFNTVSKLDTGEYSCEARNSVGYRRCPGKRMQVDDLNISGI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 LGSQSTNSSYTMNTKTGTLQFNTVSKLDTGEYSCEARNSVGYRRCPGKRMQVDDLNISGI 150 160 170 180 190 200 250 260 270 280 290 pF1KB8 IAAVVVVALVISVCGLGVCYAQRKGYFSKETSFQKSNSSSKATTMSENDFKHTKSFII :::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 IAAVVVVALVISVCGLGVCYAQRKGYFSKETSFQKSNSSSKATTMSENDFKHTKSFII 210 220 230 240 250 260 >>CCDS8494.2 JAM3 gene_id:83700|Hs108|chr11 (310 aa) initn: 551 init1: 436 opt: 642 Z-score: 545.1 bits: 108.9 E(32554): 4.8e-24 Smith-Waterman score: 642; 36.7% identity (70.3% similar) in 300 aa overlap (9-298:19-310) 10 20 30 40 50 pF1KB8 MARRSRHRLLLLLLRYLVVALGYHKAYGFSAPKDQQVVTAVEYQEAILAC .::::.: ... : .... . :: :.. . :.: CCDS84 MALRRPPRLRLCARLPDFFLLLLFRGCLIG-----AVNLKSSNRTPVVQ--EFESVELSC 10 20 30 40 50 60 70 80 90 100 pF1KB8 K-TPKKTVSSRLEWKKL-GRSVSFVYYQQTLQGDFKNRAEMID-FNIRIKNVTRSDAGKY : ..: . :.::::. .....:.... .:::. .:::.. ...: :::: :.. : CCDS84 IITDSQTSDPRIEWKKIQDEQTTYVFFDNKIQGDLAGRAEILGKTSLKIWNVTRRDSALY 60 70 80 90 100 110 110 120 130 140 150 160 pF1KB8 RCEVSAPSEQGQNLEEDTVTLEVLVAPAVPSCEVPSSALSGTVVELRCQDKEGNPAPEYT :::: : ... ....: .. : : : :..: :.::... : .. :.::..::.: :.:. CCDS84 RCEVVARNDR-KEIDEIVIELTVQVKPVTPVCRVPKAVPVGKMATLHCQESEGHPRPHYS 120 130 140 150 160 170 170 180 190 200 210 220 pF1KB8 WFKDGIRLLENPRLGSQSTNSSYTMNTKTGTLQFNTVSKLDTGEYSCEARNSVGYRRCPG :... . : . : . . :::. .:..:::: :..: : :.:.: : : :..: :: CCDS84 WYRNDVPLPTDSRANPRFRNSSFHLNSETGTLVFTAVHKDDSGQYYCIASNDAGSARCEE 180 190 200 210 220 230 230 240 250 260 270 280 pF1KB8 KRMQVDDLNISGIIAAVVVVALVISVCGLGVCYAQRKGYF--SKET--SFQ---KSNSSS ..:.: ::::.:::..:.:: :... ::.: : :.::: .:. :.. : .. . CCDS84 QEMEVYDLNIGGIIGGVLVVLAVLALITLGICCAYRRGYFINNKQDGESYKNPGKPDGVN 240 250 260 270 280 290 290 pF1KB8 KATTMSENDFKHTKSFII : :.::.: .::.: CCDS84 YIRTDEEGDFRHKSSFVI 300 310 >>CCDS1213.1 F11R gene_id:50848|Hs108|chr1 (299 aa) initn: 417 init1: 319 opt: 563 Z-score: 480.9 bits: 97.0 E(32554): 1.8e-20 Smith-Waterman score: 563; 35.2% identity (64.5% similar) in 301 aa overlap (2-298:5-299) 10 20 30 40 50 pF1KB8 MARRSRHRLLLLLLRYLVVALGYHKAYGFSAPKDQQVVTAVEYQEAILACKTPKKTV :. :. : :..: :. .:. .. :. . : : . . :.: . CCDS12 MGTKAQVERKLLCLFILAILLCSLALGSVTVHSSEPE---VRIPENNPVKLSCAYSGFS- 10 20 30 40 50 60 70 80 90 100 110 pF1KB8 SSRLEWK-KLGRSVSFVYYQQTLQGDFKNRAEMIDFNIRIKNVTRSDAGKYRCEVSAPSE : :.::: : .. .: :.. . .....:. .. .: .:.::: :.: : : :: : CCDS12 SPRVEWKFDQGDTTRLVCYNNKITASYEDRVTFLPTGITFKSVTREDTGTYTCMVS--EE 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB8 QGQNLEEDTVTLEVLVAPAVPSCEVPSSALSGTVVELRCQDKEGNPAPEYTWFKDGIRLL :.. : : : ::: :. :. ..:::: :. . : :....:.: ::::::::: . CCDS12 GGNSYGEVKVKLIVLVPPSKPTVNIPSSATIGNRAVLTCSEQDGSPPSEYTWFKDGIVMP 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB8 ENPRLGSQSTNSSYTMNTKTGTLQFNTVSKLDTGEYSCEARNSVGYRRCPGK-RMQVDDL ::. .::::..: :: : :. .: :::::::::::. : . ::.. . CCDS12 TNPKSTRAFSNSSYVLNPTTGELVFDPLSASDTGEYSCEARNGYGTPMTSNAVRMEAVER 180 190 200 210 220 230 240 250 260 270 280 290 pF1KB8 NISGIIAAVVVVALVISVCGLGVCYAQRKGYF--SKETSFQKSNSSSKATTMSENDFKHT :.. :.:::.:. ..... .:. .: .:.: .:. . .:. :. .. ::..::.: CCDS12 NVGVIVAAVLVTLILLGILVFGIWFAYSRGHFDRTKKGTSSKKVIYSQPSARSEGEFKQT 240 250 260 270 280 290 pF1KB8 KSFII .::.. CCDS12 SSFLV >>CCDS55799.1 JAM3 gene_id:83700|Hs108|chr11 (259 aa) initn: 478 init1: 421 opt: 456 Z-score: 394.5 bits: 80.8 E(32554): 1.2e-15 Smith-Waterman score: 456; 36.3% identity (69.2% similar) in 201 aa overlap (110-298:59-259) 80 90 100 110 120 130 pF1KB8 QGDFKNRAEMIDFNIRIKNVTRSDAGKYRCEVSAPSEQGQNLEEDTVTL-----EVLVAP ..: : . ...... .: .. : : CCDS55 IGAVNLKSSNRTPVVQEFESVELSCIITDSQTSDPRIEWKKIQDEQTTYVFFDNKIQVKP 30 40 50 60 70 80 140 150 160 170 180 190 pF1KB8 AVPSCEVPSSALSGTVVELRCQDKEGNPAPEYTWFKDGIRLLENPRLGSQSTNSSYTMNT ..: :.::... : .. :.::..::.: :.:.:... . : . : . . :::. .:. CCDS55 VTPVCRVPKAVPVGKMATLHCQESEGHPRPHYSWYRNDVPLPTDSRANPRFRNSSFHLNS 90 100 110 120 130 140 200 210 220 230 240 250 pF1KB8 KTGTLQFNTVSKLDTGEYSCEARNSVGYRRCPGKRMQVDDLNISGIIAAVVVVALVISVC .:::: :..: : :.:.: : : :..: :: ..:.: ::::.:::..:.:: :... CCDS55 ETGTLVFTAVHKDDSGQYYCIASNDAGSARCEEQEMEVYDLNIGGIIGGVLVVLAVLALI 150 160 170 180 190 200 260 270 280 290 pF1KB8 GLGVCYAQRKGYF--SKET--SFQ---KSNSSSKATTMSENDFKHTKSFII ::.: : :.::: .:. :.. : .. . : :.::.: .::.: CCDS55 TLGICCAYRRGYFINNKQDGESYKNPGKPDGVNYIRTDEEGDFRHKSSFVI 210 220 230 240 250 298 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 12:17:20 2016 done: Fri Nov 4 12:17:20 2016 Total Scan time: 2.520 Total Display time: -0.010 Function used was FASTA [36.3.4 Apr, 2011]