Result of FASTA (omim) for
pF1KB8368
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB8368, 622 aa
1>>>pF1KB8368 622 - 622 aa - 622 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.6764+/-0.00035; mu= 12.9760+/- 0.022
mean_var=109.1781+/-21.778, 0's: 0 Z-trim(117.3): 144 B-trim: 11 in 3/54
Lambda= 0.122746
statistics sampled from 29096 (29244) to 29096 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.705), E-opt: 0.2 (0.343), width: 16
Scan time: 10.630
The best scores are: opt bits E(85289)
XP_011512371 (OMIM: 176761,615554,615555) PREDICTE ( 622) 4336 778.9 0
NP_000940 (OMIM: 176761,615554,615555) prolactin r ( 622) 4336 778.9 0
XP_006714547 (OMIM: 176761,615554,615555) PREDICTE ( 622) 4336 778.9 0
XP_011512370 (OMIM: 176761,615554,615555) PREDICTE ( 622) 4336 778.9 0
XP_016865134 (OMIM: 176761,615554,615555) PREDICTE ( 551) 3834 689.9 5.9e-198
NP_001191243 (OMIM: 176761,615554,615555) prolacti ( 521) 3459 623.5 5.5e-178
NP_001191245 (OMIM: 176761,615554,615555) prolacti ( 376) 2367 430.1 6.9e-120
NP_001191244 (OMIM: 176761,615554,615555) prolacti ( 349) 2358 428.5 2e-119
NP_001191246 (OMIM: 176761,615554,615555) prolacti ( 288) 2014 367.5 3.6e-101
XP_016865135 (OMIM: 176761,615554,615555) PREDICTE ( 309) 2014 367.5 3.9e-101
NP_001191247 (OMIM: 176761,615554,615555) prolacti ( 268) 1628 299.1 1.3e-80
NP_001229389 (OMIM: 143890,262500,600946) growth h ( 616) 532 105.2 6.8e-22
NP_001229330 (OMIM: 143890,262500,600946) growth h ( 638) 529 104.7 1e-21
NP_001229333 (OMIM: 143890,262500,600946) growth h ( 638) 529 104.7 1e-21
NP_001229331 (OMIM: 143890,262500,600946) growth h ( 638) 529 104.7 1e-21
NP_001229332 (OMIM: 143890,262500,600946) growth h ( 638) 529 104.7 1e-21
NP_001229334 (OMIM: 143890,262500,600946) growth h ( 638) 529 104.7 1e-21
NP_000154 (OMIM: 143890,262500,600946) growth horm ( 638) 529 104.7 1e-21
NP_001229329 (OMIM: 143890,262500,600946) growth h ( 638) 529 104.7 1e-21
NP_001229335 (OMIM: 143890,262500,600946) growth h ( 638) 529 104.7 1e-21
NP_001229328 (OMIM: 143890,262500,600946) growth h ( 645) 529 104.7 1e-21
XP_011526726 (OMIM: 272430,604237) PREDICTED: cyto ( 404) 448 90.3 1.4e-17
XP_011526725 (OMIM: 272430,604237) PREDICTED: cyto ( 419) 448 90.3 1.5e-17
NP_004741 (OMIM: 272430,604237) cytokine receptor- ( 422) 448 90.3 1.5e-17
XP_011526724 (OMIM: 272430,604237) PREDICTED: cyto ( 423) 448 90.3 1.5e-17
NP_001229391 (OMIM: 143890,262500,600946) growth h ( 295) 378 77.8 6e-14
NP_786943 (OMIM: 600694) interleukin-6 receptor su ( 329) 268 58.3 4.8e-08
NP_001136256 (OMIM: 600939,614188) interleukin-11 ( 422) 269 58.6 5.2e-08
NP_001177910 (OMIM: 600694) interleukin-6 receptor ( 857) 269 58.8 9.4e-08
NP_002175 (OMIM: 600694) interleukin-6 receptor su ( 918) 269 58.8 9.9e-08
NP_001833 (OMIM: 118946) ciliary neurotrophic fact ( 372) 251 55.3 4.3e-07
XP_016869754 (OMIM: 118946) PREDICTED: ciliary neu ( 372) 251 55.3 4.3e-07
XP_016869752 (OMIM: 118946) PREDICTED: ciliary neu ( 372) 251 55.3 4.3e-07
NP_671693 (OMIM: 118946) ciliary neurotrophic fact ( 372) 251 55.3 4.3e-07
XP_016869753 (OMIM: 118946) PREDICTED: ciliary neu ( 372) 251 55.3 4.3e-07
NP_001193940 (OMIM: 118946) ciliary neurotrophic f ( 372) 251 55.3 4.3e-07
XP_016869749 (OMIM: 118946) PREDICTED: ciliary neu ( 439) 251 55.4 4.9e-07
XP_016869751 (OMIM: 118946) PREDICTED: ciliary neu ( 439) 251 55.4 4.9e-07
XP_016869750 (OMIM: 118946) PREDICTED: ciliary neu ( 439) 251 55.4 4.9e-07
XP_011544471 (OMIM: 306250,425000) PREDICTED: gran ( 385) 239 53.2 1.9e-06
XP_011543924 (OMIM: 306250,425000) PREDICTED: gran ( 385) 239 53.2 1.9e-06
XP_011543922 (OMIM: 306250,425000) PREDICTED: gran ( 389) 239 53.2 1.9e-06
XP_011544469 (OMIM: 306250,425000) PREDICTED: gran ( 389) 239 53.2 1.9e-06
XP_011543925 (OMIM: 306250,425000) PREDICTED: gran ( 383) 235 52.5 3.1e-06
XP_011544472 (OMIM: 306250,425000) PREDICTED: gran ( 383) 235 52.5 3.1e-06
XP_016884776 (OMIM: 306250,425000) PREDICTED: gran ( 383) 235 52.5 3.1e-06
XP_016885517 (OMIM: 306250,425000) PREDICTED: gran ( 383) 235 52.5 3.1e-06
XP_011543923 (OMIM: 306250,425000) PREDICTED: gran ( 386) 235 52.5 3.2e-06
XP_011544470 (OMIM: 306250,425000) PREDICTED: gran ( 386) 235 52.5 3.2e-06
NP_758448 (OMIM: 306250,425000) granulocyte-macrop ( 400) 235 52.5 3.3e-06
>>XP_011512371 (OMIM: 176761,615554,615555) PREDICTED: p (622 aa)
initn: 4336 init1: 4336 opt: 4336 Z-score: 4154.6 bits: 778.9 E(85289): 0
Smith-Waterman score: 4336; 100.0% identity (100.0% similar) in 622 aa overlap (1-622:1-622)
10 20 30 40 50 60
pF1KB8 MKENVASATVFTLLLFLNTCLLNGQLPPGKPEIFKCRSPNKETFTCWWRPGTDGGLPTNY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MKENVASATVFTLLLFLNTCLLNGQLPPGKPEIFKCRSPNKETFTCWWRPGTDGGLPTNY
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 SLTYHREGETLMHECPDYITGGPNSCHFGKQYTSMWRTYIMMVNATNQMGSSFSDELYVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SLTYHREGETLMHECPDYITGGPNSCHFGKQYTSMWRTYIMMVNATNQMGSSFSDELYVD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 VTYIVQPDPPLELAVEVKQPEDRKPYLWIKWSPPTLIDLKTGWFTLLYEIRLKPEKAAEW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VTYIVQPDPPLELAVEVKQPEDRKPYLWIKWSPPTLIDLKTGWFTLLYEIRLKPEKAAEW
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 EIHFAGQQTEFKILSLHPGQKYLVQVRCKPDHGYWSAWSPATFIQIPSDFTMNDTTVWIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EIHFAGQQTEFKILSLHPGQKYLVQVRCKPDHGYWSAWSPATFIQIPSDFTMNDTTVWIS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 VAVLSAVICLIIVWAVALKGYSMVTCIFPPVPGPKIKGFDAHLLEKGKSEELLSALGCQD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VAVLSAVICLIIVWAVALKGYSMVTCIFPPVPGPKIKGFDAHLLEKGKSEELLSALGCQD
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB8 FPPTSDYEDLLVEYLEVDDSEDQHLMSVHSKEHPSQGMKPTYLDPDTDSGRGSCDSPSLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FPPTSDYEDLLVEYLEVDDSEDQHLMSVHSKEHPSQGMKPTYLDPDTDSGRGSCDSPSLL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB8 SEKCEEPQANPSTFYDPEVIEKPENPETTHTWDPQCISMEGKIPYFHAGGSKCSTWPLPQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SEKCEEPQANPSTFYDPEVIEKPENPETTHTWDPQCISMEGKIPYFHAGGSKCSTWPLPQ
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB8 PSQHNPRSSYHNITDVCELAVGPAGAPATLLNEAGKDALKSSQTIKSREEGKATQQREVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PSQHNPRSSYHNITDVCELAVGPAGAPATLLNEAGKDALKSSQTIKSREEGKATQQREVE
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB8 SFHSETDQDTPWLLPQEKTPFGSAKPLDYVEIHKVNKDGALSLLPKQRENSGKPKKPGTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SFHSETDQDTPWLLPQEKTPFGSAKPLDYVEIHKVNKDGALSLLPKQRENSGKPKKPGTP
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB8 ENNKEYAKVSGVMDNNILVLVPDPHAKNVACFEESAKEAPPSLEQNQAEKALANFTATSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ENNKEYAKVSGVMDNNILVLVPDPHAKNVACFEESAKEAPPSLEQNQAEKALANFTATSS
550 560 570 580 590 600
610 620
pF1KB8 KCRLQLGGLDYLDPACFTHSFH
::::::::::::::::::::::
XP_011 KCRLQLGGLDYLDPACFTHSFH
610 620
>>NP_000940 (OMIM: 176761,615554,615555) prolactin recep (622 aa)
initn: 4336 init1: 4336 opt: 4336 Z-score: 4154.6 bits: 778.9 E(85289): 0
Smith-Waterman score: 4336; 100.0% identity (100.0% similar) in 622 aa overlap (1-622:1-622)
10 20 30 40 50 60
pF1KB8 MKENVASATVFTLLLFLNTCLLNGQLPPGKPEIFKCRSPNKETFTCWWRPGTDGGLPTNY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 MKENVASATVFTLLLFLNTCLLNGQLPPGKPEIFKCRSPNKETFTCWWRPGTDGGLPTNY
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 SLTYHREGETLMHECPDYITGGPNSCHFGKQYTSMWRTYIMMVNATNQMGSSFSDELYVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 SLTYHREGETLMHECPDYITGGPNSCHFGKQYTSMWRTYIMMVNATNQMGSSFSDELYVD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 VTYIVQPDPPLELAVEVKQPEDRKPYLWIKWSPPTLIDLKTGWFTLLYEIRLKPEKAAEW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 VTYIVQPDPPLELAVEVKQPEDRKPYLWIKWSPPTLIDLKTGWFTLLYEIRLKPEKAAEW
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 EIHFAGQQTEFKILSLHPGQKYLVQVRCKPDHGYWSAWSPATFIQIPSDFTMNDTTVWIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 EIHFAGQQTEFKILSLHPGQKYLVQVRCKPDHGYWSAWSPATFIQIPSDFTMNDTTVWIS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 VAVLSAVICLIIVWAVALKGYSMVTCIFPPVPGPKIKGFDAHLLEKGKSEELLSALGCQD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 VAVLSAVICLIIVWAVALKGYSMVTCIFPPVPGPKIKGFDAHLLEKGKSEELLSALGCQD
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB8 FPPTSDYEDLLVEYLEVDDSEDQHLMSVHSKEHPSQGMKPTYLDPDTDSGRGSCDSPSLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 FPPTSDYEDLLVEYLEVDDSEDQHLMSVHSKEHPSQGMKPTYLDPDTDSGRGSCDSPSLL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB8 SEKCEEPQANPSTFYDPEVIEKPENPETTHTWDPQCISMEGKIPYFHAGGSKCSTWPLPQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 SEKCEEPQANPSTFYDPEVIEKPENPETTHTWDPQCISMEGKIPYFHAGGSKCSTWPLPQ
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB8 PSQHNPRSSYHNITDVCELAVGPAGAPATLLNEAGKDALKSSQTIKSREEGKATQQREVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 PSQHNPRSSYHNITDVCELAVGPAGAPATLLNEAGKDALKSSQTIKSREEGKATQQREVE
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB8 SFHSETDQDTPWLLPQEKTPFGSAKPLDYVEIHKVNKDGALSLLPKQRENSGKPKKPGTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 SFHSETDQDTPWLLPQEKTPFGSAKPLDYVEIHKVNKDGALSLLPKQRENSGKPKKPGTP
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB8 ENNKEYAKVSGVMDNNILVLVPDPHAKNVACFEESAKEAPPSLEQNQAEKALANFTATSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 ENNKEYAKVSGVMDNNILVLVPDPHAKNVACFEESAKEAPPSLEQNQAEKALANFTATSS
550 560 570 580 590 600
610 620
pF1KB8 KCRLQLGGLDYLDPACFTHSFH
::::::::::::::::::::::
NP_000 KCRLQLGGLDYLDPACFTHSFH
610 620
>>XP_006714547 (OMIM: 176761,615554,615555) PREDICTED: p (622 aa)
initn: 4336 init1: 4336 opt: 4336 Z-score: 4154.6 bits: 778.9 E(85289): 0
Smith-Waterman score: 4336; 100.0% identity (100.0% similar) in 622 aa overlap (1-622:1-622)
10 20 30 40 50 60
pF1KB8 MKENVASATVFTLLLFLNTCLLNGQLPPGKPEIFKCRSPNKETFTCWWRPGTDGGLPTNY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MKENVASATVFTLLLFLNTCLLNGQLPPGKPEIFKCRSPNKETFTCWWRPGTDGGLPTNY
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 SLTYHREGETLMHECPDYITGGPNSCHFGKQYTSMWRTYIMMVNATNQMGSSFSDELYVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SLTYHREGETLMHECPDYITGGPNSCHFGKQYTSMWRTYIMMVNATNQMGSSFSDELYVD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 VTYIVQPDPPLELAVEVKQPEDRKPYLWIKWSPPTLIDLKTGWFTLLYEIRLKPEKAAEW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VTYIVQPDPPLELAVEVKQPEDRKPYLWIKWSPPTLIDLKTGWFTLLYEIRLKPEKAAEW
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 EIHFAGQQTEFKILSLHPGQKYLVQVRCKPDHGYWSAWSPATFIQIPSDFTMNDTTVWIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EIHFAGQQTEFKILSLHPGQKYLVQVRCKPDHGYWSAWSPATFIQIPSDFTMNDTTVWIS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 VAVLSAVICLIIVWAVALKGYSMVTCIFPPVPGPKIKGFDAHLLEKGKSEELLSALGCQD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VAVLSAVICLIIVWAVALKGYSMVTCIFPPVPGPKIKGFDAHLLEKGKSEELLSALGCQD
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB8 FPPTSDYEDLLVEYLEVDDSEDQHLMSVHSKEHPSQGMKPTYLDPDTDSGRGSCDSPSLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 FPPTSDYEDLLVEYLEVDDSEDQHLMSVHSKEHPSQGMKPTYLDPDTDSGRGSCDSPSLL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB8 SEKCEEPQANPSTFYDPEVIEKPENPETTHTWDPQCISMEGKIPYFHAGGSKCSTWPLPQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SEKCEEPQANPSTFYDPEVIEKPENPETTHTWDPQCISMEGKIPYFHAGGSKCSTWPLPQ
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB8 PSQHNPRSSYHNITDVCELAVGPAGAPATLLNEAGKDALKSSQTIKSREEGKATQQREVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PSQHNPRSSYHNITDVCELAVGPAGAPATLLNEAGKDALKSSQTIKSREEGKATQQREVE
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB8 SFHSETDQDTPWLLPQEKTPFGSAKPLDYVEIHKVNKDGALSLLPKQRENSGKPKKPGTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SFHSETDQDTPWLLPQEKTPFGSAKPLDYVEIHKVNKDGALSLLPKQRENSGKPKKPGTP
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB8 ENNKEYAKVSGVMDNNILVLVPDPHAKNVACFEESAKEAPPSLEQNQAEKALANFTATSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ENNKEYAKVSGVMDNNILVLVPDPHAKNVACFEESAKEAPPSLEQNQAEKALANFTATSS
550 560 570 580 590 600
610 620
pF1KB8 KCRLQLGGLDYLDPACFTHSFH
::::::::::::::::::::::
XP_006 KCRLQLGGLDYLDPACFTHSFH
610 620
>>XP_011512370 (OMIM: 176761,615554,615555) PREDICTED: p (622 aa)
initn: 4336 init1: 4336 opt: 4336 Z-score: 4154.6 bits: 778.9 E(85289): 0
Smith-Waterman score: 4336; 100.0% identity (100.0% similar) in 622 aa overlap (1-622:1-622)
10 20 30 40 50 60
pF1KB8 MKENVASATVFTLLLFLNTCLLNGQLPPGKPEIFKCRSPNKETFTCWWRPGTDGGLPTNY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MKENVASATVFTLLLFLNTCLLNGQLPPGKPEIFKCRSPNKETFTCWWRPGTDGGLPTNY
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 SLTYHREGETLMHECPDYITGGPNSCHFGKQYTSMWRTYIMMVNATNQMGSSFSDELYVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SLTYHREGETLMHECPDYITGGPNSCHFGKQYTSMWRTYIMMVNATNQMGSSFSDELYVD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 VTYIVQPDPPLELAVEVKQPEDRKPYLWIKWSPPTLIDLKTGWFTLLYEIRLKPEKAAEW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VTYIVQPDPPLELAVEVKQPEDRKPYLWIKWSPPTLIDLKTGWFTLLYEIRLKPEKAAEW
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 EIHFAGQQTEFKILSLHPGQKYLVQVRCKPDHGYWSAWSPATFIQIPSDFTMNDTTVWIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EIHFAGQQTEFKILSLHPGQKYLVQVRCKPDHGYWSAWSPATFIQIPSDFTMNDTTVWIS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 VAVLSAVICLIIVWAVALKGYSMVTCIFPPVPGPKIKGFDAHLLEKGKSEELLSALGCQD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VAVLSAVICLIIVWAVALKGYSMVTCIFPPVPGPKIKGFDAHLLEKGKSEELLSALGCQD
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB8 FPPTSDYEDLLVEYLEVDDSEDQHLMSVHSKEHPSQGMKPTYLDPDTDSGRGSCDSPSLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FPPTSDYEDLLVEYLEVDDSEDQHLMSVHSKEHPSQGMKPTYLDPDTDSGRGSCDSPSLL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB8 SEKCEEPQANPSTFYDPEVIEKPENPETTHTWDPQCISMEGKIPYFHAGGSKCSTWPLPQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SEKCEEPQANPSTFYDPEVIEKPENPETTHTWDPQCISMEGKIPYFHAGGSKCSTWPLPQ
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB8 PSQHNPRSSYHNITDVCELAVGPAGAPATLLNEAGKDALKSSQTIKSREEGKATQQREVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PSQHNPRSSYHNITDVCELAVGPAGAPATLLNEAGKDALKSSQTIKSREEGKATQQREVE
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB8 SFHSETDQDTPWLLPQEKTPFGSAKPLDYVEIHKVNKDGALSLLPKQRENSGKPKKPGTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SFHSETDQDTPWLLPQEKTPFGSAKPLDYVEIHKVNKDGALSLLPKQRENSGKPKKPGTP
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB8 ENNKEYAKVSGVMDNNILVLVPDPHAKNVACFEESAKEAPPSLEQNQAEKALANFTATSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ENNKEYAKVSGVMDNNILVLVPDPHAKNVACFEESAKEAPPSLEQNQAEKALANFTATSS
550 560 570 580 590 600
610 620
pF1KB8 KCRLQLGGLDYLDPACFTHSFH
::::::::::::::::::::::
XP_011 KCRLQLGGLDYLDPACFTHSFH
610 620
>>XP_016865134 (OMIM: 176761,615554,615555) PREDICTED: p (551 aa)
initn: 3834 init1: 3834 opt: 3834 Z-score: 3674.9 bits: 689.9 E(85289): 5.9e-198
Smith-Waterman score: 3834; 100.0% identity (100.0% similar) in 551 aa overlap (72-622:1-551)
50 60 70 80 90 100
pF1KB8 ETFTCWWRPGTDGGLPTNYSLTYHREGETLMHECPDYITGGPNSCHFGKQYTSMWRTYIM
::::::::::::::::::::::::::::::
XP_016 MHECPDYITGGPNSCHFGKQYTSMWRTYIM
10 20 30
110 120 130 140 150 160
pF1KB8 MVNATNQMGSSFSDELYVDVTYIVQPDPPLELAVEVKQPEDRKPYLWIKWSPPTLIDLKT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MVNATNQMGSSFSDELYVDVTYIVQPDPPLELAVEVKQPEDRKPYLWIKWSPPTLIDLKT
40 50 60 70 80 90
170 180 190 200 210 220
pF1KB8 GWFTLLYEIRLKPEKAAEWEIHFAGQQTEFKILSLHPGQKYLVQVRCKPDHGYWSAWSPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GWFTLLYEIRLKPEKAAEWEIHFAGQQTEFKILSLHPGQKYLVQVRCKPDHGYWSAWSPA
100 110 120 130 140 150
230 240 250 260 270 280
pF1KB8 TFIQIPSDFTMNDTTVWISVAVLSAVICLIIVWAVALKGYSMVTCIFPPVPGPKIKGFDA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TFIQIPSDFTMNDTTVWISVAVLSAVICLIIVWAVALKGYSMVTCIFPPVPGPKIKGFDA
160 170 180 190 200 210
290 300 310 320 330 340
pF1KB8 HLLEKGKSEELLSALGCQDFPPTSDYEDLLVEYLEVDDSEDQHLMSVHSKEHPSQGMKPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HLLEKGKSEELLSALGCQDFPPTSDYEDLLVEYLEVDDSEDQHLMSVHSKEHPSQGMKPT
220 230 240 250 260 270
350 360 370 380 390 400
pF1KB8 YLDPDTDSGRGSCDSPSLLSEKCEEPQANPSTFYDPEVIEKPENPETTHTWDPQCISMEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YLDPDTDSGRGSCDSPSLLSEKCEEPQANPSTFYDPEVIEKPENPETTHTWDPQCISMEG
280 290 300 310 320 330
410 420 430 440 450 460
pF1KB8 KIPYFHAGGSKCSTWPLPQPSQHNPRSSYHNITDVCELAVGPAGAPATLLNEAGKDALKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KIPYFHAGGSKCSTWPLPQPSQHNPRSSYHNITDVCELAVGPAGAPATLLNEAGKDALKS
340 350 360 370 380 390
470 480 490 500 510 520
pF1KB8 SQTIKSREEGKATQQREVESFHSETDQDTPWLLPQEKTPFGSAKPLDYVEIHKVNKDGAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SQTIKSREEGKATQQREVESFHSETDQDTPWLLPQEKTPFGSAKPLDYVEIHKVNKDGAL
400 410 420 430 440 450
530 540 550 560 570 580
pF1KB8 SLLPKQRENSGKPKKPGTPENNKEYAKVSGVMDNNILVLVPDPHAKNVACFEESAKEAPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SLLPKQRENSGKPKKPGTPENNKEYAKVSGVMDNNILVLVPDPHAKNVACFEESAKEAPP
460 470 480 490 500 510
590 600 610 620
pF1KB8 SLEQNQAEKALANFTATSSKCRLQLGGLDYLDPACFTHSFH
:::::::::::::::::::::::::::::::::::::::::
XP_016 SLEQNQAEKALANFTATSSKCRLQLGGLDYLDPACFTHSFH
520 530 540 550
>>NP_001191243 (OMIM: 176761,615554,615555) prolactin re (521 aa)
initn: 3456 init1: 3456 opt: 3459 Z-score: 3316.4 bits: 623.5 E(85289): 5.5e-178
Smith-Waterman score: 3459; 97.8% identity (99.0% similar) in 511 aa overlap (113-622:11-521)
90 100 110 120 130 140
pF1KB8 PNSCHFGKQYTSMWRTYIMMVNATNQMGSSFSDELYVDVTYI-VQPDPPLELAVEVKQPE
:. :.... . :::::::::::::::::
NP_001 MKENVASATVFTLLLFLNTCLLNVQPDPPLELAVEVKQPE
10 20 30 40
150 160 170 180 190 200
pF1KB8 DRKPYLWIKWSPPTLIDLKTGWFTLLYEIRLKPEKAAEWEIHFAGQQTEFKILSLHPGQK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DRKPYLWIKWSPPTLIDLKTGWFTLLYEIRLKPEKAAEWEIHFAGQQTEFKILSLHPGQK
50 60 70 80 90 100
210 220 230 240 250 260
pF1KB8 YLVQVRCKPDHGYWSAWSPATFIQIPSDFTMNDTTVWISVAVLSAVICLIIVWAVALKGY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YLVQVRCKPDHGYWSAWSPATFIQIPSDFTMNDTTVWISVAVLSAVICLIIVWAVALKGY
110 120 130 140 150 160
270 280 290 300 310 320
pF1KB8 SMVTCIFPPVPGPKIKGFDAHLLEKGKSEELLSALGCQDFPPTSDYEDLLVEYLEVDDSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SMVTCIFPPVPGPKIKGFDAHLLEKGKSEELLSALGCQDFPPTSDYEDLLVEYLEVDDSE
170 180 190 200 210 220
330 340 350 360 370 380
pF1KB8 DQHLMSVHSKEHPSQGMKPTYLDPDTDSGRGSCDSPSLLSEKCEEPQANPSTFYDPEVIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DQHLMSVHSKEHPSQGMKPTYLDPDTDSGRGSCDSPSLLSEKCEEPQANPSTFYDPEVIE
230 240 250 260 270 280
390 400 410 420 430 440
pF1KB8 KPENPETTHTWDPQCISMEGKIPYFHAGGSKCSTWPLPQPSQHNPRSSYHNITDVCELAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KPENPETTHTWDPQCISMEGKIPYFHAGGSKCSTWPLPQPSQHNPRSSYHNITDVCELAV
290 300 310 320 330 340
450 460 470 480 490 500
pF1KB8 GPAGAPATLLNEAGKDALKSSQTIKSREEGKATQQREVESFHSETDQDTPWLLPQEKTPF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GPAGAPATLLNEAGKDALKSSQTIKSREEGKATQQREVESFHSETDQDTPWLLPQEKTPF
350 360 370 380 390 400
510 520 530 540 550 560
pF1KB8 GSAKPLDYVEIHKVNKDGALSLLPKQRENSGKPKKPGTPENNKEYAKVSGVMDNNILVLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GSAKPLDYVEIHKVNKDGALSLLPKQRENSGKPKKPGTPENNKEYAKVSGVMDNNILVLV
410 420 430 440 450 460
570 580 590 600 610 620
pF1KB8 PDPHAKNVACFEESAKEAPPSLEQNQAEKALANFTATSSKCRLQLGGLDYLDPACFTHSF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PDPHAKNVACFEESAKEAPPSLEQNQAEKALANFTATSSKCRLQLGGLDYLDPACFTHSF
470 480 490 500 510 520
pF1KB8 H
:
NP_001 H
>>NP_001191245 (OMIM: 176761,615554,615555) prolactin re (376 aa)
initn: 2366 init1: 2366 opt: 2367 Z-score: 2273.4 bits: 430.1 E(85289): 6.9e-120
Smith-Waterman score: 2367; 98.8% identity (99.1% similar) in 343 aa overlap (1-343:1-342)
10 20 30 40 50 60
pF1KB8 MKENVASATVFTLLLFLNTCLLNGQLPPGKPEIFKCRSPNKETFTCWWRPGTDGGLPTNY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MKENVASATVFTLLLFLNTCLLNGQLPPGKPEIFKCRSPNKETFTCWWRPGTDGGLPTNY
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 SLTYHREGETLMHECPDYITGGPNSCHFGKQYTSMWRTYIMMVNATNQMGSSFSDELYVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SLTYHREGETLMHECPDYITGGPNSCHFGKQYTSMWRTYIMMVNATNQMGSSFSDELYVD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 VTYIVQPDPPLELAVEVKQPEDRKPYLWIKWSPPTLIDLKTGWFTLLYEIRLKPEKAAEW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VTYIVQPDPPLELAVEVKQPEDRKPYLWIKWSPPTLIDLKTGWFTLLYEIRLKPEKAAEW
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 EIHFAGQQTEFKILSLHPGQKYLVQVRCKPDHGYWSAWSPATFIQIPSDFTMNDTTVWIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EIHFAGQQTEFKILSLHPGQKYLVQVRCKPDHGYWSAWSPATFIQIPSDFTMNDTTVWIS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 VAVLSAVICLIIVWAVALKGYSMVTCIFPPVPGPKIKGFDAHLLEKGKSEELLSALGCQD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VAVLSAVICLIIVWAVALKGYSMVTCIFPPVPGPKIKGFDAHLLEKGKSEELLSALGCQD
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB8 FPPTSDYEDLLVEYLEVDDSEDQHLMSVHSKEHPSQGMKPTYLDPDTDSGRGSCDSPSLL
::::::::::::::::::::::::::::::::::::: : .:
NP_001 FPPTSDYEDLLVEYLEVDDSEDQHLMSVHSKEHPSQG-DPLMLGASHYKNLKSYRPRKIS
310 320 330 340 350
370 380 390 400 410 420
pF1KB8 SEKCEEPQANPSTFYDPEVIEKPENPETTHTWDPQCISMEGKIPYFHAGGSKCSTWPLPQ
NP_001 SQGRLAVFTKATLTTVQ
360 370
>>NP_001191244 (OMIM: 176761,615554,615555) prolactin re (349 aa)
initn: 2358 init1: 2358 opt: 2358 Z-score: 2265.2 bits: 428.5 E(85289): 2e-119
Smith-Waterman score: 2358; 100.0% identity (100.0% similar) in 336 aa overlap (1-336:1-336)
10 20 30 40 50 60
pF1KB8 MKENVASATVFTLLLFLNTCLLNGQLPPGKPEIFKCRSPNKETFTCWWRPGTDGGLPTNY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MKENVASATVFTLLLFLNTCLLNGQLPPGKPEIFKCRSPNKETFTCWWRPGTDGGLPTNY
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 SLTYHREGETLMHECPDYITGGPNSCHFGKQYTSMWRTYIMMVNATNQMGSSFSDELYVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SLTYHREGETLMHECPDYITGGPNSCHFGKQYTSMWRTYIMMVNATNQMGSSFSDELYVD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 VTYIVQPDPPLELAVEVKQPEDRKPYLWIKWSPPTLIDLKTGWFTLLYEIRLKPEKAAEW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VTYIVQPDPPLELAVEVKQPEDRKPYLWIKWSPPTLIDLKTGWFTLLYEIRLKPEKAAEW
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 EIHFAGQQTEFKILSLHPGQKYLVQVRCKPDHGYWSAWSPATFIQIPSDFTMNDTTVWIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EIHFAGQQTEFKILSLHPGQKYLVQVRCKPDHGYWSAWSPATFIQIPSDFTMNDTTVWIS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 VAVLSAVICLIIVWAVALKGYSMVTCIFPPVPGPKIKGFDAHLLEKGKSEELLSALGCQD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VAVLSAVICLIIVWAVALKGYSMVTCIFPPVPGPKIKGFDAHLLEKGKSEELLSALGCQD
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB8 FPPTSDYEDLLVEYLEVDDSEDQHLMSVHSKEHPSQGMKPTYLDPDTDSGRGSCDSPSLL
::::::::::::::::::::::::::::::::::::
NP_001 FPPTSDYEDLLVEYLEVDDSEDQHLMSVHSKEHPSQEREQRQAQEARDS
310 320 330 340
370 380 390 400 410 420
pF1KB8 SEKCEEPQANPSTFYDPEVIEKPENPETTHTWDPQCISMEGKIPYFHAGGSKCSTWPLPQ
>>NP_001191246 (OMIM: 176761,615554,615555) prolactin re (288 aa)
initn: 2014 init1: 2014 opt: 2014 Z-score: 1937.2 bits: 367.5 E(85289): 3.6e-101
Smith-Waterman score: 2014; 100.0% identity (100.0% similar) in 285 aa overlap (1-285:1-285)
10 20 30 40 50 60
pF1KB8 MKENVASATVFTLLLFLNTCLLNGQLPPGKPEIFKCRSPNKETFTCWWRPGTDGGLPTNY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MKENVASATVFTLLLFLNTCLLNGQLPPGKPEIFKCRSPNKETFTCWWRPGTDGGLPTNY
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 SLTYHREGETLMHECPDYITGGPNSCHFGKQYTSMWRTYIMMVNATNQMGSSFSDELYVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SLTYHREGETLMHECPDYITGGPNSCHFGKQYTSMWRTYIMMVNATNQMGSSFSDELYVD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 VTYIVQPDPPLELAVEVKQPEDRKPYLWIKWSPPTLIDLKTGWFTLLYEIRLKPEKAAEW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VTYIVQPDPPLELAVEVKQPEDRKPYLWIKWSPPTLIDLKTGWFTLLYEIRLKPEKAAEW
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 EIHFAGQQTEFKILSLHPGQKYLVQVRCKPDHGYWSAWSPATFIQIPSDFTMNDTTVWIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EIHFAGQQTEFKILSLHPGQKYLVQVRCKPDHGYWSAWSPATFIQIPSDFTMNDTTVWIS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 VAVLSAVICLIIVWAVALKGYSMVTCIFPPVPGPKIKGFDAHLLEKGKSEELLSALGCQD
:::::::::::::::::::::::::::::::::::::::::::::
NP_001 VAVLSAVICLIIVWAVALKGYSMVTCIFPPVPGPKIKGFDAHLLEVTP
250 260 270 280
310 320 330 340 350 360
pF1KB8 FPPTSDYEDLLVEYLEVDDSEDQHLMSVHSKEHPSQGMKPTYLDPDTDSGRGSCDSPSLL
>>XP_016865135 (OMIM: 176761,615554,615555) PREDICTED: p (309 aa)
initn: 2014 init1: 2014 opt: 2014 Z-score: 1936.8 bits: 367.5 E(85289): 3.9e-101
Smith-Waterman score: 2014; 100.0% identity (100.0% similar) in 285 aa overlap (1-285:1-285)
10 20 30 40 50 60
pF1KB8 MKENVASATVFTLLLFLNTCLLNGQLPPGKPEIFKCRSPNKETFTCWWRPGTDGGLPTNY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MKENVASATVFTLLLFLNTCLLNGQLPPGKPEIFKCRSPNKETFTCWWRPGTDGGLPTNY
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 SLTYHREGETLMHECPDYITGGPNSCHFGKQYTSMWRTYIMMVNATNQMGSSFSDELYVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SLTYHREGETLMHECPDYITGGPNSCHFGKQYTSMWRTYIMMVNATNQMGSSFSDELYVD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 VTYIVQPDPPLELAVEVKQPEDRKPYLWIKWSPPTLIDLKTGWFTLLYEIRLKPEKAAEW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VTYIVQPDPPLELAVEVKQPEDRKPYLWIKWSPPTLIDLKTGWFTLLYEIRLKPEKAAEW
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 EIHFAGQQTEFKILSLHPGQKYLVQVRCKPDHGYWSAWSPATFIQIPSDFTMNDTTVWIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EIHFAGQQTEFKILSLHPGQKYLVQVRCKPDHGYWSAWSPATFIQIPSDFTMNDTTVWIS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 VAVLSAVICLIIVWAVALKGYSMVTCIFPPVPGPKIKGFDAHLLEKGKSEELLSALGCQD
:::::::::::::::::::::::::::::::::::::::::::::
XP_016 VAVLSAVICLIIVWAVALKGYSMVTCIFPPVPGPKIKGFDAHLLEDRLCTPGRCCVSTGL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB8 FPPTSDYEDLLVEYLEVDDSEDQHLMSVHSKEHPSQGMKPTYLDPDTDSGRGSCDSPSLL
XP_016 TDLDYSCST
622 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 12:18:35 2016 done: Fri Nov 4 12:18:37 2016
Total Scan time: 10.630 Total Display time: 0.100
Function used was FASTA [36.3.4 Apr, 2011]