FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB8372, 165 aa 1>>>pF1KB8372 165 - 165 aa - 165 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.2534+/-0.000585; mu= 12.2333+/- 0.035 mean_var=55.5084+/-10.598, 0's: 0 Z-trim(111.6): 10 B-trim: 0 in 0/51 Lambda= 0.172145 statistics sampled from 12478 (12486) to 12478 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.77), E-opt: 0.2 (0.384), width: 16 Scan time: 1.670 The best scores are: opt bits E(32554) CCDS640.1 GADD45A gene_id:1647|Hs108|chr1 ( 165) 1103 281.2 2e-76 CCDS55605.1 GADD45A gene_id:1647|Hs108|chr1 ( 131) 812 208.9 9.3e-55 CCDS32868.1 GADD45B gene_id:4616|Hs108|chr19 ( 160) 607 158.0 2.4e-39 CCDS6686.1 GADD45G gene_id:10912|Hs108|chr9 ( 159) 583 152.0 1.5e-37 CCDS72806.1 GADD45A gene_id:1647|Hs108|chr1 ( 60) 291 79.4 4.1e-16 >>CCDS640.1 GADD45A gene_id:1647|Hs108|chr1 (165 aa) initn: 1103 init1: 1103 opt: 1103 Z-score: 1485.5 bits: 281.2 E(32554): 2e-76 Smith-Waterman score: 1103; 100.0% identity (100.0% similar) in 165 aa overlap (1-165:1-165) 10 20 30 40 50 60 pF1KB8 MTLEEFSAGEQKTERMDKVGDALEEVLSKALSQRTITVGVYEAAKLLNVDPDNVVLCLLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS64 MTLEEFSAGEQKTERMDKVGDALEEVLSKALSQRTITVGVYEAAKLLNVDPDNVVLCLLA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 ADEDDDRDVALQIHFTLIQAFCCENDINILRVSNPGRLAELLLLETDAGPAASEGAEQPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS64 ADEDDDRDVALQIHFTLIQAFCCENDINILRVSNPGRLAELLLLETDAGPAASEGAEQPP 70 80 90 100 110 120 130 140 150 160 pF1KB8 DLHCVLVTNPHSSQWKDPALSQLICFCRESRYMDQWVPVINLPER ::::::::::::::::::::::::::::::::::::::::::::: CCDS64 DLHCVLVTNPHSSQWKDPALSQLICFCRESRYMDQWVPVINLPER 130 140 150 160 >>CCDS55605.1 GADD45A gene_id:1647|Hs108|chr1 (131 aa) initn: 883 init1: 812 opt: 812 Z-score: 1096.6 bits: 208.9 E(32554): 9.3e-55 Smith-Waterman score: 818; 78.8% identity (78.8% similar) in 165 aa overlap (1-165:1-131) 10 20 30 40 50 60 pF1KB8 MTLEEFSAGEQKTERMDKVGDALEEVLSKALSQRTITVGVYEAAKLLNVDPDNVVLCLLA :::::::::::::: ::::::::::: CCDS55 MTLEEFSAGEQKTES----------------------------------DPDNVVLCLLA 10 20 70 80 90 100 110 120 pF1KB8 ADEDDDRDVALQIHFTLIQAFCCENDINILRVSNPGRLAELLLLETDAGPAASEGAEQPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 ADEDDDRDVALQIHFTLIQAFCCENDINILRVSNPGRLAELLLLETDAGPAASEGAEQPP 30 40 50 60 70 80 130 140 150 160 pF1KB8 DLHCVLVTNPHSSQWKDPALSQLICFCRESRYMDQWVPVINLPER ::::::::::::::::::::::::::::::::::::::::::::: CCDS55 DLHCVLVTNPHSSQWKDPALSQLICFCRESRYMDQWVPVINLPER 90 100 110 120 130 >>CCDS32868.1 GADD45B gene_id:4616|Hs108|chr19 (160 aa) initn: 616 init1: 413 opt: 607 Z-score: 820.0 bits: 158.0 E(32554): 2.4e-39 Smith-Waterman score: 607; 55.8% identity (78.8% similar) in 165 aa overlap (1-165:1-160) 10 20 30 40 50 60 pF1KB8 MTLEEFSAGEQKTERMDKVGDALEEVLSKALSQRTITVGVYEAAKLLNVDPDNVVLCLLA :::::. : .. ...:. : :.::.: : : .::::::.:::.:::::.::::::: CCDS32 MTLEELVACDNAAQKMQTVTAAVEELLVAAQRQDRLTVGVYESAKLMNVDPDSVVLCLLA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 ADEDDDRDVALQIHFTLIQAFCCENDINILRVSNPGRLAELLLLETDAGPAASEGAEQPP ::... :.::::::::::.:::.:::::.:::. :::.:: . :: ..:. . CCDS32 IDEEEEDDIALQIHFTLIQSFCCDNDINIVRVSGMQRLAQLL-----GEPAETQGTTEAR 70 80 90 100 110 130 140 150 160 pF1KB8 DLHCVLVTNPHSSQWKDPALSQLICFCRESRYMDQWVPVINLPER ::::.::::::.. ::. .: .. .:.::: .:::: :.: :: CCDS32 DLHCLLVTNPHTDAWKSHGLVEVASYCEESRGNNQWVPYISLQER 120 130 140 150 160 >>CCDS6686.1 GADD45G gene_id:10912|Hs108|chr9 (159 aa) initn: 375 init1: 375 opt: 583 Z-score: 787.8 bits: 152.0 E(32554): 1.5e-37 Smith-Waterman score: 583; 54.5% identity (77.2% similar) in 167 aa overlap (1-164:1-159) 10 20 30 40 50 pF1KB8 MTLEEFSAGE---QKTERMDKVGDALEEVLSKALSQRTITVGVYEAAKLLNVDPDNVVLC ::::: . . ..: ::. .: ::.:.: .: : .:.::::.::.::::::::..: CCDS66 MTLEEVRGQDTVPESTARMQGAGKALHELLLSAQRQGCLTAGVYESAKVLNVDPDNVTFC 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB8 LLAADEDDDRDVALQIHFTLIQAFCCENDINILRVSNPGRLAELLLLETDAGPAASEGAE .::: :.:. :.::::::::::::::::::.:.::.. ::: .. .:.: : CCDS66 VLAAGEEDEGDIALQIHFTLIQAFCCENDIDIVRVGDVQRLAAIV--------GAGEEAG 70 80 90 100 110 120 130 140 150 160 pF1KB8 QPPDLHCVLVTNPHSSQWKDPALSQLICFCRESRYMDQWVPVINLPER : ::::.:..::. . :::::: .: ::.::: ...::: :.::: CCDS66 APGDLHCILISNPNEDAWKDPALEKLSLFCEESRSVNDWVPSITLPE 120 130 140 150 >>CCDS72806.1 GADD45A gene_id:1647|Hs108|chr1 (60 aa) initn: 291 init1: 291 opt: 291 Z-score: 402.8 bits: 79.4 E(32554): 4.1e-16 Smith-Waterman score: 291; 100.0% identity (100.0% similar) in 49 aa overlap (1-49:1-49) 10 20 30 40 50 60 pF1KB8 MTLEEFSAGEQKTERMDKVGDALEEVLSKALSQRTITVGVYEAAKLLNVDPDNVVLCLLA ::::::::::::::::::::::::::::::::::::::::::::::::: CCDS72 MTLEEFSAGEQKTERMDKVGDALEEVLSKALSQRTITVGVYEAAKLLNVIHIHLNGRILP 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 ADEDDDRDVALQIHFTLIQAFCCENDINILRVSNPGRLAELLLLETDAGPAASEGAEQPP 165 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 12:20:12 2016 done: Fri Nov 4 12:20:13 2016 Total Scan time: 1.670 Total Display time: -0.010 Function used was FASTA [36.3.4 Apr, 2011]