Result of FASTA (omim) for
pF1KB8372
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB8372, 165 aa
1>>>pF1KB8372 165 - 165 aa - 165 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.0586+/-0.000278; mu= 13.2986+/- 0.017
mean_var=55.9737+/-10.815, 0's: 0 Z-trim(118.3): 13 B-trim: 0 in 0/53
Lambda= 0.171428
statistics sampled from 31120 (31133) to 31120 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.757), E-opt: 0.2 (0.365), width: 16
Scan time: 5.210
The best scores are: opt bits E(85289)
NP_001915 (OMIM: 126335) growth arrest and DNA dam ( 165) 1103 280.1 1.1e-75
NP_001186670 (OMIM: 126335) growth arrest and DNA ( 131) 812 208.1 4.1e-54
NP_056490 (OMIM: 604948) growth arrest and DNA dam ( 160) 607 157.5 9e-39
NP_006696 (OMIM: 604949) growth arrest and DNA dam ( 159) 583 151.5 5.5e-37
XP_016882311 (OMIM: 604948) PREDICTED: growth arre ( 176) 467 122.9 2.6e-28
XP_011516465 (OMIM: 604949) PREDICTED: growth arre ( 125) 459 120.8 7.6e-28
NP_001186671 (OMIM: 126335) growth arrest and DNA ( 60) 291 79.1 1.3e-15
NP_001007 (OMIM: 603660) 40S ribosomal protein S12 ( 132) 150 44.4 8e-05
>>NP_001915 (OMIM: 126335) growth arrest and DNA damage- (165 aa)
initn: 1103 init1: 1103 opt: 1103 Z-score: 1479.9 bits: 280.1 E(85289): 1.1e-75
Smith-Waterman score: 1103; 100.0% identity (100.0% similar) in 165 aa overlap (1-165:1-165)
10 20 30 40 50 60
pF1KB8 MTLEEFSAGEQKTERMDKVGDALEEVLSKALSQRTITVGVYEAAKLLNVDPDNVVLCLLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MTLEEFSAGEQKTERMDKVGDALEEVLSKALSQRTITVGVYEAAKLLNVDPDNVVLCLLA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 ADEDDDRDVALQIHFTLIQAFCCENDINILRVSNPGRLAELLLLETDAGPAASEGAEQPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ADEDDDRDVALQIHFTLIQAFCCENDINILRVSNPGRLAELLLLETDAGPAASEGAEQPP
70 80 90 100 110 120
130 140 150 160
pF1KB8 DLHCVLVTNPHSSQWKDPALSQLICFCRESRYMDQWVPVINLPER
:::::::::::::::::::::::::::::::::::::::::::::
NP_001 DLHCVLVTNPHSSQWKDPALSQLICFCRESRYMDQWVPVINLPER
130 140 150 160
>>NP_001186670 (OMIM: 126335) growth arrest and DNA dama (131 aa)
initn: 883 init1: 812 opt: 812 Z-score: 1092.5 bits: 208.1 E(85289): 4.1e-54
Smith-Waterman score: 818; 78.8% identity (78.8% similar) in 165 aa overlap (1-165:1-131)
10 20 30 40 50 60
pF1KB8 MTLEEFSAGEQKTERMDKVGDALEEVLSKALSQRTITVGVYEAAKLLNVDPDNVVLCLLA
:::::::::::::: :::::::::::
NP_001 MTLEEFSAGEQKTES----------------------------------DPDNVVLCLLA
10 20
70 80 90 100 110 120
pF1KB8 ADEDDDRDVALQIHFTLIQAFCCENDINILRVSNPGRLAELLLLETDAGPAASEGAEQPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ADEDDDRDVALQIHFTLIQAFCCENDINILRVSNPGRLAELLLLETDAGPAASEGAEQPP
30 40 50 60 70 80
130 140 150 160
pF1KB8 DLHCVLVTNPHSSQWKDPALSQLICFCRESRYMDQWVPVINLPER
:::::::::::::::::::::::::::::::::::::::::::::
NP_001 DLHCVLVTNPHSSQWKDPALSQLICFCRESRYMDQWVPVINLPER
90 100 110 120 130
>>NP_056490 (OMIM: 604948) growth arrest and DNA damage- (160 aa)
initn: 616 init1: 413 opt: 607 Z-score: 817.1 bits: 157.5 E(85289): 9e-39
Smith-Waterman score: 607; 55.8% identity (78.8% similar) in 165 aa overlap (1-165:1-160)
10 20 30 40 50 60
pF1KB8 MTLEEFSAGEQKTERMDKVGDALEEVLSKALSQRTITVGVYEAAKLLNVDPDNVVLCLLA
:::::. : .. ...:. : :.::.: : : .::::::.:::.:::::.:::::::
NP_056 MTLEELVACDNAAQKMQTVTAAVEELLVAAQRQDRLTVGVYESAKLMNVDPDSVVLCLLA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 ADEDDDRDVALQIHFTLIQAFCCENDINILRVSNPGRLAELLLLETDAGPAASEGAEQPP
::... :.::::::::::.:::.:::::.:::. :::.:: . :: ..:. .
NP_056 IDEEEEDDIALQIHFTLIQSFCCDNDINIVRVSGMQRLAQLL-----GEPAETQGTTEAR
70 80 90 100 110
130 140 150 160
pF1KB8 DLHCVLVTNPHSSQWKDPALSQLICFCRESRYMDQWVPVINLPER
::::.::::::.. ::. .: .. .:.::: .:::: :.: ::
NP_056 DLHCLLVTNPHTDAWKSHGLVEVASYCEESRGNNQWVPYISLQER
120 130 140 150 160
>>NP_006696 (OMIM: 604949) growth arrest and DNA damage- (159 aa)
initn: 375 init1: 375 opt: 583 Z-score: 785.1 bits: 151.5 E(85289): 5.5e-37
Smith-Waterman score: 583; 54.5% identity (77.2% similar) in 167 aa overlap (1-164:1-159)
10 20 30 40 50
pF1KB8 MTLEEFSAGE---QKTERMDKVGDALEEVLSKALSQRTITVGVYEAAKLLNVDPDNVVLC
::::: . . ..: ::. .: ::.:.: .: : .:.::::.::.::::::::..:
NP_006 MTLEEVRGQDTVPESTARMQGAGKALHELLLSAQRQGCLTAGVYESAKVLNVDPDNVTFC
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB8 LLAADEDDDRDVALQIHFTLIQAFCCENDINILRVSNPGRLAELLLLETDAGPAASEGAE
.::: :.:. :.::::::::::::::::::.:.::.. ::: .. .:.: :
NP_006 VLAAGEEDEGDIALQIHFTLIQAFCCENDIDIVRVGDVQRLAAIV--------GAGEEAG
70 80 90 100 110
120 130 140 150 160
pF1KB8 QPPDLHCVLVTNPHSSQWKDPALSQLICFCRESRYMDQWVPVINLPER
: ::::.:..::. . :::::: .: ::.::: ...::: :.:::
NP_006 APGDLHCILISNPNEDAWKDPALEKLSLFCEESRSVNDWVPSITLPE
120 130 140 150
>>XP_016882311 (OMIM: 604948) PREDICTED: growth arrest a (176 aa)
initn: 476 init1: 413 opt: 467 Z-score: 629.3 bits: 122.9 E(85289): 2.6e-28
Smith-Waterman score: 467; 56.4% identity (78.9% similar) in 133 aa overlap (1-133:1-128)
10 20 30 40 50 60
pF1KB8 MTLEEFSAGEQKTERMDKVGDALEEVLSKALSQRTITVGVYEAAKLLNVDPDNVVLCLLA
:::::. : .. ...:. : :.::.: : : .::::::.:::.:::::.:::::::
XP_016 MTLEELVACDNAAQKMQTVTAAVEELLVAAQRQDRLTVGVYESAKLMNVDPDSVVLCLLA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 ADEDDDRDVALQIHFTLIQAFCCENDINILRVSNPGRLAELLLLETDAGPAASEGAEQPP
::... :.::::::::::.:::.:::::.:::. :::.:: . :: ..:. .
XP_016 IDEEEEDDIALQIHFTLIQSFCCDNDINIVRVSGMQRLAQLL-----GEPAETQGTTEAR
70 80 90 100 110
130 140 150 160
pF1KB8 DLHCVLVTNPHSSQWKDPALSQLICFCRESRYMDQWVPVINLPER
::::.::: ..:
XP_016 DLHCLLVTVSRASALPRHARAPGPVFVNKVGLTGPAQLSAQPRLACPVGSRAGASSPRKL
120 130 140 150 160 170
>>XP_011516465 (OMIM: 604949) PREDICTED: growth arrest a (125 aa)
initn: 277 init1: 262 opt: 459 Z-score: 620.9 bits: 120.8 E(85289): 7.6e-28
Smith-Waterman score: 459; 57.4% identity (79.1% similar) in 115 aa overlap (50-164:19-125)
20 30 40 50 60 70
pF1KB8 GDALEEVLSKALSQRTITVGVYEAAKLLNVDPDNVVLCLLAADEDDDRDVALQIHFTLIQ
:::::..:.::: :.:. :.::::::::::
XP_011 MTLEEVRGQDTVPESTARDPDNVTFCVLAAGEEDEGDIALQIHFTLIQ
10 20 30 40
80 90 100 110 120 130
pF1KB8 AFCCENDINILRVSNPGRLAELLLLETDAGPAASEGAEQPPDLHCVLVTNPHSSQWKDPA
::::::::.:.::.. ::: .. .:.: : : ::::.:..::. . :::::
XP_011 AFCCENDIDIVRVGDVQRLAAIV--------GAGEEAGAPGDLHCILISNPNEDAWKDPA
50 60 70 80 90 100
140 150 160
pF1KB8 LSQLICFCRESRYMDQWVPVINLPER
: .: ::.::: ...::: :.:::
XP_011 LEKLSLFCEESRSVNDWVPSITLPE
110 120
>>NP_001186671 (OMIM: 126335) growth arrest and DNA dama (60 aa)
initn: 291 init1: 291 opt: 291 Z-score: 401.4 bits: 79.1 E(85289): 1.3e-15
Smith-Waterman score: 291; 100.0% identity (100.0% similar) in 49 aa overlap (1-49:1-49)
10 20 30 40 50 60
pF1KB8 MTLEEFSAGEQKTERMDKVGDALEEVLSKALSQRTITVGVYEAAKLLNVDPDNVVLCLLA
:::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MTLEEFSAGEQKTERMDKVGDALEEVLSKALSQRTITVGVYEAAKLLNVIHIHLNGRILP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 ADEDDDRDVALQIHFTLIQAFCCENDINILRVSNPGRLAELLLLETDAGPAASEGAEQPP
>>NP_001007 (OMIM: 603660) 40S ribosomal protein S12 [Ho (132 aa)
initn: 111 init1: 72 opt: 150 Z-score: 207.6 bits: 44.4 E(85289): 8e-05
Smith-Waterman score: 158; 31.3% identity (57.5% similar) in 134 aa overlap (16-145:12-130)
10 20 30 40 50 60
pF1KB8 MTLEEFSAGEQKTERMDKVGDALEEVLSKALSQRTITVGVYEAAKLLNVDPDNVVLCLLA
:: :. ::.:::. :: . .. :. :::: : : .. ::.::
NP_001 MAEEGIAAGGVMD-VNTALQEVLKTALIHDGLARGIREAAKAL--DKRQAHLCVLA
10 20 30 40 50
70 80 90 100 110
pF1KB8 ADEDDDRDVALQIHFTLIQAFCCENDINILRVSNPGRLAE---LLLLETDAGPAASEGAE
.. :. .. :..:.: :..::...:.. .:.: : .. .. : :
NP_001 SNCDE------PMYVKLVEALCAEHQINLIKVDDNKKLGEWVGLCKIDREGKPRKVVGCS
60 70 80 90 100
120 130 140 150 160
pF1KB8 QPPDLHCVLVTN-PHSSQWKDPALSQLICFCRESRYMDQWVPVINLPER
::.: . . :: :: . :
NP_001 ------CVVVKDYGKESQAKDVIEEYFKCKK
110 120 130
165 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 12:20:13 2016 done: Fri Nov 4 12:20:14 2016
Total Scan time: 5.210 Total Display time: -0.020
Function used was FASTA [36.3.4 Apr, 2011]