FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB8373, 171 aa 1>>>pF1KB8373 171 - 171 aa - 171 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.0715+/-0.000351; mu= 12.9916+/- 0.022 mean_var=54.5070+/-10.855, 0's: 0 Z-trim(113.1): 32 B-trim: 0 in 0/55 Lambda= 0.173719 statistics sampled from 22318 (22343) to 22318 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.664), E-opt: 0.2 (0.262), width: 16 Scan time: 4.430 The best scores are: opt bits E(85289) NP_002961 (OMIM: 308800,313020) diamine acetyltran ( 171) 1172 301.5 4.2e-82 XP_016885209 (OMIM: 308800,313020) PREDICTED: diam ( 206) 715 187.0 1.5e-47 NP_597998 (OMIM: 611463) diamine acetyltransferase ( 170) 544 144.1 1e-34 NP_001307774 (OMIM: 611463) diamine acetyltransfer ( 249) 463 123.9 1.8e-28 XP_016879562 (OMIM: 611463) PREDICTED: diamine ace ( 205) 332 91.0 1.2e-18 NP_001307776 (OMIM: 611463) diamine acetyltransfer ( 136) 238 67.4 1e-11 NP_001307775 (OMIM: 611463) diamine acetyltransfer ( 215) 184 54.0 1.8e-07 XP_016879563 (OMIM: 611463) PREDICTED: diamine ace ( 171) 157 47.2 1.6e-05 >>NP_002961 (OMIM: 308800,313020) diamine acetyltransfer (171 aa) initn: 1172 init1: 1172 opt: 1172 Z-score: 1595.0 bits: 301.5 E(85289): 4.2e-82 Smith-Waterman score: 1172; 100.0% identity (100.0% similar) in 171 aa overlap (1-171:1-171) 10 20 30 40 50 60 pF1KB8 MAKFVIRPATAADCSDILRLIKELAKYEYMEEQVILTEKDLLEDGFGEHPFYHCLVAEVP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 MAKFVIRPATAADCSDILRLIKELAKYEYMEEQVILTEKDLLEDGFGEHPFYHCLVAEVP 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 KEHWTPEGHSIVGFAMYYFTYDPWIGKLLYLEDFFVMSDYRGFGIGSEILKNLSQVAMRC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 KEHWTPEGHSIVGFAMYYFTYDPWIGKLLYLEDFFVMSDYRGFGIGSEILKNLSQVAMRC 70 80 90 100 110 120 130 140 150 160 170 pF1KB8 RCSSMHFLVAEWNEPSINFYKRRGASDLSSEEGWRLFKIDKEYLLKMATEE ::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 RCSSMHFLVAEWNEPSINFYKRRGASDLSSEEGWRLFKIDKEYLLKMATEE 130 140 150 160 170 >>XP_016885209 (OMIM: 308800,313020) PREDICTED: diamine (206 aa) initn: 715 init1: 715 opt: 715 Z-score: 974.7 bits: 187.0 E(85289): 1.5e-47 Smith-Waterman score: 715; 100.0% identity (100.0% similar) in 104 aa overlap (68-171:103-206) 40 50 60 70 80 90 pF1KB8 EKDLLEDGFGEHPFYHCLVAEVPKEHWTPEGHSIVGFAMYYFTYDPWIGKLLYLEDFFVM :::::::::::::::::::::::::::::: XP_016 FKTYDRPLILQLQLLWNVFLLHISCDALITGHSIVGFAMYYFTYDPWIGKLLYLEDFFVM 80 90 100 110 120 130 100 110 120 130 140 150 pF1KB8 SDYRGFGIGSEILKNLSQVAMRCRCSSMHFLVAEWNEPSINFYKRRGASDLSSEEGWRLF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SDYRGFGIGSEILKNLSQVAMRCRCSSMHFLVAEWNEPSINFYKRRGASDLSSEEGWRLF 140 150 160 170 180 190 160 170 pF1KB8 KIDKEYLLKMATEE :::::::::::::: XP_016 KIDKEYLLKMATEE 200 >>NP_597998 (OMIM: 611463) diamine acetyltransferase 2 i (170 aa) initn: 550 init1: 535 opt: 544 Z-score: 744.4 bits: 144.1 E(85289): 1e-34 Smith-Waterman score: 544; 46.4% identity (75.0% similar) in 168 aa overlap (1-168:1-168) 10 20 30 40 50 60 pF1KB8 MAKFVIRPATAADCSDILRLIKELAKYEYMEEQVILTEKDLLEDGFGEHPFYHCLVAEVP ::. :: : .::.::::::.:::..: . .:: ..:. : ::::..:::::::::. NP_597 MASVRIREAKEGDCGDILRLIRELAEFEKLSDQVKISEEALRADGFGDNPFYHCLVAEIL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 KEHWTPEGHSIVGFAMYYFTYDPWIGKLLYLEDFFVMSDYRGFGIGSEILKNLSQVAMRC : .::...::: :. : :. .::::..:: .::: ::::.:.:....::. NP_597 PAPGKLLGPCVVGYGIYYFIYSTWKGRTIYLEDIYVMPEYRGQGIGSKIIKKVAEVALDK 70 80 90 100 110 120 130 140 150 160 170 pF1KB8 RCSSMHFLVAEWNEPSINFYKRRGASDLSSEEGWRLFKIDKEYLLKMATEE ::.... : .::. ....:: ::.::. :::..: .. : :.: NP_597 GCSQFRLAVLDWNQRAMDLYKALGAQDLTEAEGWHFFCFQGEATRKLAGK 130 140 150 160 170 >>NP_001307774 (OMIM: 611463) diamine acetyltransferase (249 aa) initn: 469 init1: 454 opt: 463 Z-score: 632.1 bits: 123.9 E(85289): 1.8e-28 Smith-Waterman score: 463; 44.5% identity (74.7% similar) in 146 aa overlap (23-168:102-247) 10 20 30 40 50 pF1KB8 MAKFVIRPATAADCSDILRLIKELAKYEYMEEQVILTEKDLLEDGFGEHPFY :::..: . .:: ..:. : ::::..::: NP_001 DPDGFRADPRGQGGRLWRYPEADSGEDCRPELAEFEKLSDQVKISEEALRADGFGDNPFY 80 90 100 110 120 130 60 70 80 90 100 110 pF1KB8 HCLVAEVPKEHWTPEGHSIVGFAMYYFTYDPWIGKLLYLEDFFVMSDYRGFGIGSEILKN ::::::. : .::...::: :. : :. .::::..:: .::: ::::.:.:. NP_001 HCLVAEILPAPGKLLGPCVVGYGIYYFIYSTWKGRTIYLEDIYVMPEYRGQGIGSKIIKK 140 150 160 170 180 190 120 130 140 150 160 170 pF1KB8 LSQVAMRCRCSSMHFLVAEWNEPSINFYKRRGASDLSSEEGWRLFKIDKEYLLKMATEE ...::. ::.... : .::. ....:: ::.::. :::..: .. : :.: NP_001 VAEVALDKGCSQFRLAVLDWNQRAMDLYKALGAQDLTEAEGWHFFCFQGEATRKLAGK 200 210 220 230 240 >>XP_016879562 (OMIM: 611463) PREDICTED: diamine acetylt (205 aa) initn: 332 init1: 332 opt: 332 Z-score: 456.0 bits: 91.0 E(85289): 1.2e-18 Smith-Waterman score: 332; 48.9% identity (76.6% similar) in 94 aa overlap (23-116:102-195) 10 20 30 40 50 pF1KB8 MAKFVIRPATAADCSDILRLIKELAKYEYMEEQVILTEKDLLEDGFGEHPFY :::..: . .:: ..:. : ::::..::: XP_016 DPDGFRADPRGQGGRLWRYPEADSGEDCRPELAEFEKLSDQVKISEEALRADGFGDNPFY 80 90 100 110 120 130 60 70 80 90 100 110 pF1KB8 HCLVAEVPKEHWTPEGHSIVGFAMYYFTYDPWIGKLLYLEDFFVMSDYRGFGIGSEILKN ::::::. : .::...::: :. : :. .::::..:: .::: ::::.:.:. XP_016 HCLVAEILPAPGKLLGPCVVGYGIYYFIYSTWKGRTIYLEDIYVMPEYRGQGIGSKIIKK 140 150 160 170 180 190 120 130 140 150 160 170 pF1KB8 LSQVAMRCRCSSMHFLVAEWNEPSINFYKRRGASDLSSEEGWRLFKIDKEYLLKMATEE ...: XP_016 VAEVRRWVGRQVRT 200 >>NP_001307776 (OMIM: 611463) diamine acetyltransferase (136 aa) initn: 395 init1: 238 opt: 238 Z-score: 331.5 bits: 67.4 E(85289): 1e-11 Smith-Waterman score: 358; 39.3% identity (61.9% similar) in 168 aa overlap (1-168:1-134) 10 20 30 40 50 60 pF1KB8 MAKFVIRPATAADCSDILRLIKELAKYEYMEEQVILTEKDLLEDGFGEHPFYHCLVAEVP ::. :: : .::.::::::.:::..: . .:: ..:. : ::::..:::::::::. NP_001 MASVRIREAKEGDCGDILRLIRELAEFEKLSDQVKISEEALRADGFGDNPFYHCLVAEIL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 KEHWTPEGHSIVGFAMYYFTYDPWIGKLLYLEDFFVMSDYRGFGIGSEILKNLSQVAMRC : :::: : ::::.:.:....::. NP_001 ----------------------PAPGKLL------------GQGIGSKIIKKVAEVALDK 70 80 130 140 150 160 170 pF1KB8 RCSSMHFLVAEWNEPSINFYKRRGASDLSSEEGWRLFKIDKEYLLKMATEE ::.... : .::. ....:: ::.::. :::..: .. : :.: NP_001 GCSQFRLAVLDWNQRAMDLYKALGAQDLTEAEGWHFFCFQGEATRKLAGK 90 100 110 120 130 >>NP_001307775 (OMIM: 611463) diamine acetyltransferase (215 aa) initn: 314 init1: 171 opt: 184 Z-score: 255.2 bits: 54.0 E(85289): 1.8e-07 Smith-Waterman score: 277; 36.3% identity (59.6% similar) in 146 aa overlap (23-168:102-213) 10 20 30 40 50 pF1KB8 MAKFVIRPATAADCSDILRLIKELAKYEYMEEQVILTEKDLLEDGFGEHPFY :::..: . .:: ..:. : ::::..::: NP_001 DPDGFRADPRGQGGRLWRYPEADSGEDCRPELAEFEKLSDQVKISEEALRADGFGDNPFY 80 90 100 110 120 130 60 70 80 90 100 110 pF1KB8 HCLVAEVPKEHWTPEGHSIVGFAMYYFTYDPWIGKLLYLEDFFVMSDYRGFGIGSEILKN ::::::. : :::: : ::::.:.:. NP_001 HCLVAEIL----------------------PAPGKLL------------GQGIGSKIIKK 140 150 120 130 140 150 160 170 pF1KB8 LSQVAMRCRCSSMHFLVAEWNEPSINFYKRRGASDLSSEEGWRLFKIDKEYLLKMATEE ...::. ::.... : .::. ....:: ::.::. :::..: .. : :.: NP_001 VAEVALDKGCSQFRLAVLDWNQRAMDLYKALGAQDLTEAEGWHFFCFQGEATRKLAGK 160 170 180 190 200 210 >>XP_016879563 (OMIM: 611463) PREDICTED: diamine acetylt (171 aa) initn: 192 init1: 157 opt: 157 Z-score: 220.2 bits: 47.2 E(85289): 1.6e-05 Smith-Waterman score: 157; 56.8% identity (83.8% similar) in 37 aa overlap (23-59:102-138) 10 20 30 40 50 pF1KB8 MAKFVIRPATAADCSDILRLIKELAKYEYMEEQVILTEKDLLEDGFGEHPFY :::..: . .:: ..:. : ::::..::: XP_016 DPDGFRADPRGQGGRLWRYPEADSGEDCRPELAEFEKLSDQVKISEEALRADGFGDNPFY 80 90 100 110 120 130 60 70 80 90 100 110 pF1KB8 HCLVAEVPKEHWTPEGHSIVGFAMYYFTYDPWIGKLLYLEDFFVMSDYRGFGIGSEILKN ::::::. XP_016 HCLVAEILPAPGKLLGQGIGSKIIKKVAEVRRWVGRQVRT 140 150 160 170 171 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 12:20:47 2016 done: Fri Nov 4 12:20:48 2016 Total Scan time: 4.430 Total Display time: -0.020 Function used was FASTA [36.3.4 Apr, 2011]