FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB8374, 628 aa 1>>>pF1KB8374 628 - 628 aa - 628 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 8.8127+/-0.000414; mu= 4.9443+/- 0.026 mean_var=217.2482+/-43.883, 0's: 0 Z-trim(119.3): 58 B-trim: 48 in 1/49 Lambda= 0.087015 statistics sampled from 33143 (33206) to 33143 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.716), E-opt: 0.2 (0.389), width: 16 Scan time: 11.930 The best scores are: opt bits E(85289) NP_001129028 (OMIM: 603772) cytoplasmic dynein 1 i ( 628) 4224 543.3 9.5e-154 XP_011514164 (OMIM: 603772) PREDICTED: cytoplasmic ( 628) 4224 543.3 9.5e-154 XP_016867294 (OMIM: 603772) PREDICTED: cytoplasmic ( 628) 4224 543.3 9.5e-154 NP_001265350 (OMIM: 603772) cytoplasmic dynein 1 i ( 625) 3860 497.6 5.4e-140 NP_004402 (OMIM: 603772) cytoplasmic dynein 1 inte ( 645) 3764 485.6 2.3e-136 XP_016867293 (OMIM: 603772) PREDICTED: cytoplasmic ( 645) 3764 485.6 2.3e-136 XP_011514163 (OMIM: 603772) PREDICTED: cytoplasmic ( 645) 3764 485.6 2.3e-136 NP_001129029 (OMIM: 603772) cytoplasmic dynein 1 i ( 608) 3438 444.6 4.7e-124 XP_016867295 (OMIM: 603772) PREDICTED: cytoplasmic ( 513) 3383 437.7 4.9e-122 XP_006712410 (OMIM: 603331) PREDICTED: cytoplasmic ( 631) 3382 437.6 6.3e-122 XP_016859014 (OMIM: 603331) PREDICTED: cytoplasmic ( 631) 3382 437.6 6.3e-122 NP_001307812 (OMIM: 603331) cytoplasmic dynein 1 i ( 632) 3370 436.1 1.8e-121 NP_001307811 (OMIM: 603331) cytoplasmic dynein 1 i ( 632) 3370 436.1 1.8e-121 NP_001265351 (OMIM: 603772) cytoplasmic dynein 1 i ( 602) 3212 416.2 1.6e-115 NP_001258714 (OMIM: 603331) cytoplasmic dynein 1 i ( 638) 3173 411.4 5e-114 NP_001369 (OMIM: 603331) cytoplasmic dynein 1 inte ( 638) 3173 411.4 5e-114 NP_001258716 (OMIM: 603331) cytoplasmic dynein 1 i ( 630) 3082 399.9 1.4e-110 NP_001258715 (OMIM: 603331) cytoplasmic dynein 1 i ( 630) 3082 399.9 1.4e-110 XP_011514165 (OMIM: 603772) PREDICTED: cytoplasmic ( 530) 2923 379.9 1.2e-104 NP_001307813 (OMIM: 603331) cytoplasmic dynein 1 i ( 611) 2785 362.6 2.2e-99 NP_001258719 (OMIM: 603331) cytoplasmic dynein 1 i ( 611) 2785 362.6 2.2e-99 NP_001258717 (OMIM: 603331) cytoplasmic dynein 1 i ( 612) 2773 361.1 6.3e-99 NP_001258718 (OMIM: 603331) cytoplasmic dynein 1 i ( 612) 2773 361.1 6.3e-99 XP_016867296 (OMIM: 603772) PREDICTED: cytoplasmic ( 357) 1678 223.5 1e-57 NP_075462 (OMIM: 605483,612444) dynein intermediat ( 605) 401 63.4 2.7e-09 XP_011523427 (OMIM: 605483,612444) PREDICTED: dyne ( 649) 401 63.4 2.9e-09 NP_001166281 (OMIM: 605483,612444) dynein intermed ( 593) 388 61.7 8.3e-09 XP_006716821 (OMIM: 244400,604366) PREDICTED: dyne ( 522) 365 58.8 5.6e-08 NP_036276 (OMIM: 244400,604366) dynein intermediat ( 699) 365 58.9 7e-08 NP_001268357 (OMIM: 244400,604366) dynein intermed ( 703) 365 58.9 7e-08 XP_011516149 (OMIM: 244400,604366) PREDICTED: dyne ( 621) 337 55.3 7.3e-07 XP_011516148 (OMIM: 244400,604366) PREDICTED: dyne ( 660) 337 55.4 7.7e-07 XP_011517481 (OMIM: 613363,615633) PREDICTED: WD r ( 508) 316 52.6 3.9e-06 XP_011516151 (OMIM: 244400,604366) PREDICTED: dyne ( 546) 247 44.0 0.0017 >>NP_001129028 (OMIM: 603772) cytoplasmic dynein 1 inter (628 aa) initn: 4224 init1: 4224 opt: 4224 Z-score: 2881.3 bits: 543.3 E(85289): 9.5e-154 Smith-Waterman score: 4224; 100.0% identity (100.0% similar) in 628 aa overlap (1-628:1-628) 10 20 30 40 50 60 pF1KB8 MSDKSDLKAELERKKQRLAQIREEKKRKEEERKKKEADMQQKKEPVQDDSDLDRKRRETE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MSDKSDLKAELERKKQRLAQIREEKKRKEEERKKKEADMQQKKEPVQDDSDLDRKRRETE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 ALLQSIGISPEPPLVPTPMSPSSKSVSTPSEAGSQDSGDLGPLTRTLQWDTDPSVLQLQS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ALLQSIGISPEPPLVPTPMSPSSKSVSTPSEAGSQDSGDLGPLTRTLQWDTDPSVLQLQS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 DSELGRRLHKLGVSKVTQVDFLPREVVSYSKETQTPLATHQSEEDEEDEEMVESKVGQDS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DSELGRRLHKLGVSKVTQVDFLPREVVSYSKETQTPLATHQSEEDEEDEEMVESKVGQDS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 ELENQDKKQEVKEAPPRELTEEEKQQILHSEEFLIFFDRTIRVIERALAEDSDIFFDYSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ELENQDKKQEVKEAPPRELTEEEKQQILHSEEFLIFFDRTIRVIERALAEDSDIFFDYSG 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 RELEEKDGDVQAGANLSFNRQFYDEHWSKHRVVTCMDWSLQYPELMVASYNNNEDAPHEP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RELEEKDGDVQAGANLSFNRQFYDEHWSKHRVVTCMDWSLQYPELMVASYNNNEDAPHEP 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 DGVALVWNMKFKKTTPEYVFHCQSSVMSVCFARFHPNLVVGGTYSGQIVLWDNRSHRRTP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DGVALVWNMKFKKTTPEYVFHCQSSVMSVCFARFHPNLVVGGTYSGQIVLWDNRSHRRTP 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB8 VQRTPLSAAAHTHPVYCVNVVGTQNAHNLITVSTDGKMCSWSLDMLSTPQESMELVYNKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VQRTPLSAAAHTHPVYCVNVVGTQNAHNLITVSTDGKMCSWSLDMLSTPQESMELVYNKS 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB8 KPVAVTGMAFPTGDVNNFVVGSEEGTVYTACRHGSKAGIGEVFEGHQGPVTGINCHMAVG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KPVAVTGMAFPTGDVNNFVVGSEEGTVYTACRHGSKAGIGEVFEGHQGPVTGINCHMAVG 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB8 PIDFSHLFVTSSFDWTVKLWTTKHNKPLYSFEDNADYVYDVMWSPVHPALFACVDGMGRL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PIDFSHLFVTSSFDWTVKLWTTKHNKPLYSFEDNADYVYDVMWSPVHPALFACVDGMGRL 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB8 DLWNLNNDTEVPTASVAIEGASALNRVRWAQAGKEVAVGDSEGRIWVYDVGELAVPHNDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DLWNLNNDTEVPTASVAIEGASALNRVRWAQAGKEVAVGDSEGRIWVYDVGELAVPHNDE 550 560 570 580 590 600 610 620 pF1KB8 WTRFARTLVEIRANRADSEEEGTVELSA :::::::::::::::::::::::::::: NP_001 WTRFARTLVEIRANRADSEEEGTVELSA 610 620 >>XP_011514164 (OMIM: 603772) PREDICTED: cytoplasmic dyn (628 aa) initn: 4224 init1: 4224 opt: 4224 Z-score: 2881.3 bits: 543.3 E(85289): 9.5e-154 Smith-Waterman score: 4224; 100.0% identity (100.0% similar) in 628 aa overlap (1-628:1-628) 10 20 30 40 50 60 pF1KB8 MSDKSDLKAELERKKQRLAQIREEKKRKEEERKKKEADMQQKKEPVQDDSDLDRKRRETE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MSDKSDLKAELERKKQRLAQIREEKKRKEEERKKKEADMQQKKEPVQDDSDLDRKRRETE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 ALLQSIGISPEPPLVPTPMSPSSKSVSTPSEAGSQDSGDLGPLTRTLQWDTDPSVLQLQS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ALLQSIGISPEPPLVPTPMSPSSKSVSTPSEAGSQDSGDLGPLTRTLQWDTDPSVLQLQS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 DSELGRRLHKLGVSKVTQVDFLPREVVSYSKETQTPLATHQSEEDEEDEEMVESKVGQDS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DSELGRRLHKLGVSKVTQVDFLPREVVSYSKETQTPLATHQSEEDEEDEEMVESKVGQDS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 ELENQDKKQEVKEAPPRELTEEEKQQILHSEEFLIFFDRTIRVIERALAEDSDIFFDYSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ELENQDKKQEVKEAPPRELTEEEKQQILHSEEFLIFFDRTIRVIERALAEDSDIFFDYSG 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 RELEEKDGDVQAGANLSFNRQFYDEHWSKHRVVTCMDWSLQYPELMVASYNNNEDAPHEP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RELEEKDGDVQAGANLSFNRQFYDEHWSKHRVVTCMDWSLQYPELMVASYNNNEDAPHEP 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 DGVALVWNMKFKKTTPEYVFHCQSSVMSVCFARFHPNLVVGGTYSGQIVLWDNRSHRRTP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DGVALVWNMKFKKTTPEYVFHCQSSVMSVCFARFHPNLVVGGTYSGQIVLWDNRSHRRTP 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB8 VQRTPLSAAAHTHPVYCVNVVGTQNAHNLITVSTDGKMCSWSLDMLSTPQESMELVYNKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VQRTPLSAAAHTHPVYCVNVVGTQNAHNLITVSTDGKMCSWSLDMLSTPQESMELVYNKS 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB8 KPVAVTGMAFPTGDVNNFVVGSEEGTVYTACRHGSKAGIGEVFEGHQGPVTGINCHMAVG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KPVAVTGMAFPTGDVNNFVVGSEEGTVYTACRHGSKAGIGEVFEGHQGPVTGINCHMAVG 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB8 PIDFSHLFVTSSFDWTVKLWTTKHNKPLYSFEDNADYVYDVMWSPVHPALFACVDGMGRL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PIDFSHLFVTSSFDWTVKLWTTKHNKPLYSFEDNADYVYDVMWSPVHPALFACVDGMGRL 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB8 DLWNLNNDTEVPTASVAIEGASALNRVRWAQAGKEVAVGDSEGRIWVYDVGELAVPHNDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DLWNLNNDTEVPTASVAIEGASALNRVRWAQAGKEVAVGDSEGRIWVYDVGELAVPHNDE 550 560 570 580 590 600 610 620 pF1KB8 WTRFARTLVEIRANRADSEEEGTVELSA :::::::::::::::::::::::::::: XP_011 WTRFARTLVEIRANRADSEEEGTVELSA 610 620 >>XP_016867294 (OMIM: 603772) PREDICTED: cytoplasmic dyn (628 aa) initn: 4224 init1: 4224 opt: 4224 Z-score: 2881.3 bits: 543.3 E(85289): 9.5e-154 Smith-Waterman score: 4224; 100.0% identity (100.0% similar) in 628 aa overlap (1-628:1-628) 10 20 30 40 50 60 pF1KB8 MSDKSDLKAELERKKQRLAQIREEKKRKEEERKKKEADMQQKKEPVQDDSDLDRKRRETE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MSDKSDLKAELERKKQRLAQIREEKKRKEEERKKKEADMQQKKEPVQDDSDLDRKRRETE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 ALLQSIGISPEPPLVPTPMSPSSKSVSTPSEAGSQDSGDLGPLTRTLQWDTDPSVLQLQS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ALLQSIGISPEPPLVPTPMSPSSKSVSTPSEAGSQDSGDLGPLTRTLQWDTDPSVLQLQS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 DSELGRRLHKLGVSKVTQVDFLPREVVSYSKETQTPLATHQSEEDEEDEEMVESKVGQDS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DSELGRRLHKLGVSKVTQVDFLPREVVSYSKETQTPLATHQSEEDEEDEEMVESKVGQDS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 ELENQDKKQEVKEAPPRELTEEEKQQILHSEEFLIFFDRTIRVIERALAEDSDIFFDYSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ELENQDKKQEVKEAPPRELTEEEKQQILHSEEFLIFFDRTIRVIERALAEDSDIFFDYSG 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 RELEEKDGDVQAGANLSFNRQFYDEHWSKHRVVTCMDWSLQYPELMVASYNNNEDAPHEP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RELEEKDGDVQAGANLSFNRQFYDEHWSKHRVVTCMDWSLQYPELMVASYNNNEDAPHEP 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 DGVALVWNMKFKKTTPEYVFHCQSSVMSVCFARFHPNLVVGGTYSGQIVLWDNRSHRRTP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DGVALVWNMKFKKTTPEYVFHCQSSVMSVCFARFHPNLVVGGTYSGQIVLWDNRSHRRTP 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB8 VQRTPLSAAAHTHPVYCVNVVGTQNAHNLITVSTDGKMCSWSLDMLSTPQESMELVYNKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VQRTPLSAAAHTHPVYCVNVVGTQNAHNLITVSTDGKMCSWSLDMLSTPQESMELVYNKS 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB8 KPVAVTGMAFPTGDVNNFVVGSEEGTVYTACRHGSKAGIGEVFEGHQGPVTGINCHMAVG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KPVAVTGMAFPTGDVNNFVVGSEEGTVYTACRHGSKAGIGEVFEGHQGPVTGINCHMAVG 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB8 PIDFSHLFVTSSFDWTVKLWTTKHNKPLYSFEDNADYVYDVMWSPVHPALFACVDGMGRL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PIDFSHLFVTSSFDWTVKLWTTKHNKPLYSFEDNADYVYDVMWSPVHPALFACVDGMGRL 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB8 DLWNLNNDTEVPTASVAIEGASALNRVRWAQAGKEVAVGDSEGRIWVYDVGELAVPHNDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DLWNLNNDTEVPTASVAIEGASALNRVRWAQAGKEVAVGDSEGRIWVYDVGELAVPHNDE 550 560 570 580 590 600 610 620 pF1KB8 WTRFARTLVEIRANRADSEEEGTVELSA :::::::::::::::::::::::::::: XP_016 WTRFARTLVEIRANRADSEEEGTVELSA 610 620 >>NP_001265350 (OMIM: 603772) cytoplasmic dynein 1 inter (625 aa) initn: 3878 init1: 3416 opt: 3860 Z-score: 2634.4 bits: 497.6 E(85289): 5.4e-140 Smith-Waterman score: 3996; 94.3% identity (94.3% similar) in 645 aa overlap (1-628:1-625) 10 20 30 40 50 60 pF1KB8 MSDKSDLKAELERKKQRLAQIREEKKRKEEERKKKEADMQQKKEPVQDDSDLDRKRRETE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MSDKSDLKAELERKKQRLAQIREEKKRKEEERKKKEADMQQKKEPVQDDSDLDRKRRETE 10 20 30 40 50 60 70 80 90 100 pF1KB8 ALLQSIGISPEPPLV-----------------PTPMSPSSKSVSTPSEAGSQDSGDLGPL ::::::::::::::: :::::::::::::::::::::::::::: NP_001 ALLQSIGISPEPPLVQPLHFLTWDTCYFHYLVPTPMSPSSKSVSTPSEAGSQDSGDLGPL 70 80 90 100 110 120 110 120 130 140 150 160 pF1KB8 TRTLQWDTDPSVLQLQSDSELGRRLHKLGVSKVTQVDFLPREVVSYSKETQTPLATHQSE :: :::::::::::::::::::::::::::::::::::::: NP_001 TR--------------------RRLHKLGVSKVTQVDFLPREVVSYSKETQTPLATHQSE 130 140 150 160 170 180 190 200 210 220 pF1KB8 EDEEDEEMVESKVGQDSELENQDKKQEVKEAPPRELTEEEKQQILHSEEFLIFFDRTIRV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EDEEDEEMVESKVGQDSELENQDKKQEVKEAPPRELTEEEKQQILHSEEFLIFFDRTIRV 170 180 190 200 210 220 230 240 250 260 270 280 pF1KB8 IERALAEDSDIFFDYSGRELEEKDGDVQAGANLSFNRQFYDEHWSKHRVVTCMDWSLQYP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IERALAEDSDIFFDYSGRELEEKDGDVQAGANLSFNRQFYDEHWSKHRVVTCMDWSLQYP 230 240 250 260 270 280 290 300 310 320 330 340 pF1KB8 ELMVASYNNNEDAPHEPDGVALVWNMKFKKTTPEYVFHCQSSVMSVCFARFHPNLVVGGT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ELMVASYNNNEDAPHEPDGVALVWNMKFKKTTPEYVFHCQSSVMSVCFARFHPNLVVGGT 290 300 310 320 330 340 350 360 370 380 390 400 pF1KB8 YSGQIVLWDNRSHRRTPVQRTPLSAAAHTHPVYCVNVVGTQNAHNLITVSTDGKMCSWSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YSGQIVLWDNRSHRRTPVQRTPLSAAAHTHPVYCVNVVGTQNAHNLITVSTDGKMCSWSL 350 360 370 380 390 400 410 420 430 440 450 460 pF1KB8 DMLSTPQESMELVYNKSKPVAVTGMAFPTGDVNNFVVGSEEGTVYTACRHGSKAGIGEVF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DMLSTPQESMELVYNKSKPVAVTGMAFPTGDVNNFVVGSEEGTVYTACRHGSKAGIGEVF 410 420 430 440 450 460 470 480 490 500 510 520 pF1KB8 EGHQGPVTGINCHMAVGPIDFSHLFVTSSFDWTVKLWTTKHNKPLYSFEDNADYVYDVMW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EGHQGPVTGINCHMAVGPIDFSHLFVTSSFDWTVKLWTTKHNKPLYSFEDNADYVYDVMW 470 480 490 500 510 520 530 540 550 560 570 580 pF1KB8 SPVHPALFACVDGMGRLDLWNLNNDTEVPTASVAIEGASALNRVRWAQAGKEVAVGDSEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SPVHPALFACVDGMGRLDLWNLNNDTEVPTASVAIEGASALNRVRWAQAGKEVAVGDSEG 530 540 550 560 570 580 590 600 610 620 pF1KB8 RIWVYDVGELAVPHNDEWTRFARTLVEIRANRADSEEEGTVELSA ::::::::::::::::::::::::::::::::::::::::::::: NP_001 RIWVYDVGELAVPHNDEWTRFARTLVEIRANRADSEEEGTVELSA 590 600 610 620 >>NP_004402 (OMIM: 603772) cytoplasmic dynein 1 intermed (645 aa) initn: 3758 init1: 3758 opt: 3764 Z-score: 2569.0 bits: 485.6 E(85289): 2.3e-136 Smith-Waterman score: 4180; 97.4% identity (97.4% similar) in 645 aa overlap (1-628:1-645) 10 20 30 40 50 60 pF1KB8 MSDKSDLKAELERKKQRLAQIREEKKRKEEERKKKEADMQQKKEPVQDDSDLDRKRRETE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 MSDKSDLKAELERKKQRLAQIREEKKRKEEERKKKEADMQQKKEPVQDDSDLDRKRRETE 10 20 30 40 50 60 70 80 90 100 pF1KB8 ALLQSIGISPEPPLV-----------------PTPMSPSSKSVSTPSEAGSQDSGDLGPL ::::::::::::::: :::::::::::::::::::::::::::: NP_004 ALLQSIGISPEPPLVQPLHFLTWDTCYFHYLVPTPMSPSSKSVSTPSEAGSQDSGDLGPL 70 80 90 100 110 120 110 120 130 140 150 160 pF1KB8 TRTLQWDTDPSVLQLQSDSELGRRLHKLGVSKVTQVDFLPREVVSYSKETQTPLATHQSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 TRTLQWDTDPSVLQLQSDSELGRRLHKLGVSKVTQVDFLPREVVSYSKETQTPLATHQSE 130 140 150 160 170 180 170 180 190 200 210 220 pF1KB8 EDEEDEEMVESKVGQDSELENQDKKQEVKEAPPRELTEEEKQQILHSEEFLIFFDRTIRV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 EDEEDEEMVESKVGQDSELENQDKKQEVKEAPPRELTEEEKQQILHSEEFLIFFDRTIRV 190 200 210 220 230 240 230 240 250 260 270 280 pF1KB8 IERALAEDSDIFFDYSGRELEEKDGDVQAGANLSFNRQFYDEHWSKHRVVTCMDWSLQYP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 IERALAEDSDIFFDYSGRELEEKDGDVQAGANLSFNRQFYDEHWSKHRVVTCMDWSLQYP 250 260 270 280 290 300 290 300 310 320 330 340 pF1KB8 ELMVASYNNNEDAPHEPDGVALVWNMKFKKTTPEYVFHCQSSVMSVCFARFHPNLVVGGT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 ELMVASYNNNEDAPHEPDGVALVWNMKFKKTTPEYVFHCQSSVMSVCFARFHPNLVVGGT 310 320 330 340 350 360 350 360 370 380 390 400 pF1KB8 YSGQIVLWDNRSHRRTPVQRTPLSAAAHTHPVYCVNVVGTQNAHNLITVSTDGKMCSWSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 YSGQIVLWDNRSHRRTPVQRTPLSAAAHTHPVYCVNVVGTQNAHNLITVSTDGKMCSWSL 370 380 390 400 410 420 410 420 430 440 450 460 pF1KB8 DMLSTPQESMELVYNKSKPVAVTGMAFPTGDVNNFVVGSEEGTVYTACRHGSKAGIGEVF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 DMLSTPQESMELVYNKSKPVAVTGMAFPTGDVNNFVVGSEEGTVYTACRHGSKAGIGEVF 430 440 450 460 470 480 470 480 490 500 510 520 pF1KB8 EGHQGPVTGINCHMAVGPIDFSHLFVTSSFDWTVKLWTTKHNKPLYSFEDNADYVYDVMW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 EGHQGPVTGINCHMAVGPIDFSHLFVTSSFDWTVKLWTTKHNKPLYSFEDNADYVYDVMW 490 500 510 520 530 540 530 540 550 560 570 580 pF1KB8 SPVHPALFACVDGMGRLDLWNLNNDTEVPTASVAIEGASALNRVRWAQAGKEVAVGDSEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 SPVHPALFACVDGMGRLDLWNLNNDTEVPTASVAIEGASALNRVRWAQAGKEVAVGDSEG 550 560 570 580 590 600 590 600 610 620 pF1KB8 RIWVYDVGELAVPHNDEWTRFARTLVEIRANRADSEEEGTVELSA ::::::::::::::::::::::::::::::::::::::::::::: NP_004 RIWVYDVGELAVPHNDEWTRFARTLVEIRANRADSEEEGTVELSA 610 620 630 640 >>XP_016867293 (OMIM: 603772) PREDICTED: cytoplasmic dyn (645 aa) initn: 3758 init1: 3758 opt: 3764 Z-score: 2569.0 bits: 485.6 E(85289): 2.3e-136 Smith-Waterman score: 4180; 97.4% identity (97.4% similar) in 645 aa overlap (1-628:1-645) 10 20 30 40 50 60 pF1KB8 MSDKSDLKAELERKKQRLAQIREEKKRKEEERKKKEADMQQKKEPVQDDSDLDRKRRETE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MSDKSDLKAELERKKQRLAQIREEKKRKEEERKKKEADMQQKKEPVQDDSDLDRKRRETE 10 20 30 40 50 60 70 80 90 100 pF1KB8 ALLQSIGISPEPPLV-----------------PTPMSPSSKSVSTPSEAGSQDSGDLGPL ::::::::::::::: :::::::::::::::::::::::::::: XP_016 ALLQSIGISPEPPLVQPLHFLTWDTCYFHYLVPTPMSPSSKSVSTPSEAGSQDSGDLGPL 70 80 90 100 110 120 110 120 130 140 150 160 pF1KB8 TRTLQWDTDPSVLQLQSDSELGRRLHKLGVSKVTQVDFLPREVVSYSKETQTPLATHQSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TRTLQWDTDPSVLQLQSDSELGRRLHKLGVSKVTQVDFLPREVVSYSKETQTPLATHQSE 130 140 150 160 170 180 170 180 190 200 210 220 pF1KB8 EDEEDEEMVESKVGQDSELENQDKKQEVKEAPPRELTEEEKQQILHSEEFLIFFDRTIRV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EDEEDEEMVESKVGQDSELENQDKKQEVKEAPPRELTEEEKQQILHSEEFLIFFDRTIRV 190 200 210 220 230 240 230 240 250 260 270 280 pF1KB8 IERALAEDSDIFFDYSGRELEEKDGDVQAGANLSFNRQFYDEHWSKHRVVTCMDWSLQYP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IERALAEDSDIFFDYSGRELEEKDGDVQAGANLSFNRQFYDEHWSKHRVVTCMDWSLQYP 250 260 270 280 290 300 290 300 310 320 330 340 pF1KB8 ELMVASYNNNEDAPHEPDGVALVWNMKFKKTTPEYVFHCQSSVMSVCFARFHPNLVVGGT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ELMVASYNNNEDAPHEPDGVALVWNMKFKKTTPEYVFHCQSSVMSVCFARFHPNLVVGGT 310 320 330 340 350 360 350 360 370 380 390 400 pF1KB8 YSGQIVLWDNRSHRRTPVQRTPLSAAAHTHPVYCVNVVGTQNAHNLITVSTDGKMCSWSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YSGQIVLWDNRSHRRTPVQRTPLSAAAHTHPVYCVNVVGTQNAHNLITVSTDGKMCSWSL 370 380 390 400 410 420 410 420 430 440 450 460 pF1KB8 DMLSTPQESMELVYNKSKPVAVTGMAFPTGDVNNFVVGSEEGTVYTACRHGSKAGIGEVF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DMLSTPQESMELVYNKSKPVAVTGMAFPTGDVNNFVVGSEEGTVYTACRHGSKAGIGEVF 430 440 450 460 470 480 470 480 490 500 510 520 pF1KB8 EGHQGPVTGINCHMAVGPIDFSHLFVTSSFDWTVKLWTTKHNKPLYSFEDNADYVYDVMW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EGHQGPVTGINCHMAVGPIDFSHLFVTSSFDWTVKLWTTKHNKPLYSFEDNADYVYDVMW 490 500 510 520 530 540 530 540 550 560 570 580 pF1KB8 SPVHPALFACVDGMGRLDLWNLNNDTEVPTASVAIEGASALNRVRWAQAGKEVAVGDSEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SPVHPALFACVDGMGRLDLWNLNNDTEVPTASVAIEGASALNRVRWAQAGKEVAVGDSEG 550 560 570 580 590 600 590 600 610 620 pF1KB8 RIWVYDVGELAVPHNDEWTRFARTLVEIRANRADSEEEGTVELSA ::::::::::::::::::::::::::::::::::::::::::::: XP_016 RIWVYDVGELAVPHNDEWTRFARTLVEIRANRADSEEEGTVELSA 610 620 630 640 >>XP_011514163 (OMIM: 603772) PREDICTED: cytoplasmic dyn (645 aa) initn: 3758 init1: 3758 opt: 3764 Z-score: 2569.0 bits: 485.6 E(85289): 2.3e-136 Smith-Waterman score: 4180; 97.4% identity (97.4% similar) in 645 aa overlap (1-628:1-645) 10 20 30 40 50 60 pF1KB8 MSDKSDLKAELERKKQRLAQIREEKKRKEEERKKKEADMQQKKEPVQDDSDLDRKRRETE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MSDKSDLKAELERKKQRLAQIREEKKRKEEERKKKEADMQQKKEPVQDDSDLDRKRRETE 10 20 30 40 50 60 70 80 90 100 pF1KB8 ALLQSIGISPEPPLV-----------------PTPMSPSSKSVSTPSEAGSQDSGDLGPL ::::::::::::::: :::::::::::::::::::::::::::: XP_011 ALLQSIGISPEPPLVQPLHFLTWDTCYFHYLVPTPMSPSSKSVSTPSEAGSQDSGDLGPL 70 80 90 100 110 120 110 120 130 140 150 160 pF1KB8 TRTLQWDTDPSVLQLQSDSELGRRLHKLGVSKVTQVDFLPREVVSYSKETQTPLATHQSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TRTLQWDTDPSVLQLQSDSELGRRLHKLGVSKVTQVDFLPREVVSYSKETQTPLATHQSE 130 140 150 160 170 180 170 180 190 200 210 220 pF1KB8 EDEEDEEMVESKVGQDSELENQDKKQEVKEAPPRELTEEEKQQILHSEEFLIFFDRTIRV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EDEEDEEMVESKVGQDSELENQDKKQEVKEAPPRELTEEEKQQILHSEEFLIFFDRTIRV 190 200 210 220 230 240 230 240 250 260 270 280 pF1KB8 IERALAEDSDIFFDYSGRELEEKDGDVQAGANLSFNRQFYDEHWSKHRVVTCMDWSLQYP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IERALAEDSDIFFDYSGRELEEKDGDVQAGANLSFNRQFYDEHWSKHRVVTCMDWSLQYP 250 260 270 280 290 300 290 300 310 320 330 340 pF1KB8 ELMVASYNNNEDAPHEPDGVALVWNMKFKKTTPEYVFHCQSSVMSVCFARFHPNLVVGGT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ELMVASYNNNEDAPHEPDGVALVWNMKFKKTTPEYVFHCQSSVMSVCFARFHPNLVVGGT 310 320 330 340 350 360 350 360 370 380 390 400 pF1KB8 YSGQIVLWDNRSHRRTPVQRTPLSAAAHTHPVYCVNVVGTQNAHNLITVSTDGKMCSWSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 YSGQIVLWDNRSHRRTPVQRTPLSAAAHTHPVYCVNVVGTQNAHNLITVSTDGKMCSWSL 370 380 390 400 410 420 410 420 430 440 450 460 pF1KB8 DMLSTPQESMELVYNKSKPVAVTGMAFPTGDVNNFVVGSEEGTVYTACRHGSKAGIGEVF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DMLSTPQESMELVYNKSKPVAVTGMAFPTGDVNNFVVGSEEGTVYTACRHGSKAGIGEVF 430 440 450 460 470 480 470 480 490 500 510 520 pF1KB8 EGHQGPVTGINCHMAVGPIDFSHLFVTSSFDWTVKLWTTKHNKPLYSFEDNADYVYDVMW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EGHQGPVTGINCHMAVGPIDFSHLFVTSSFDWTVKLWTTKHNKPLYSFEDNADYVYDVMW 490 500 510 520 530 540 530 540 550 560 570 580 pF1KB8 SPVHPALFACVDGMGRLDLWNLNNDTEVPTASVAIEGASALNRVRWAQAGKEVAVGDSEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SPVHPALFACVDGMGRLDLWNLNNDTEVPTASVAIEGASALNRVRWAQAGKEVAVGDSEG 550 560 570 580 590 600 590 600 610 620 pF1KB8 RIWVYDVGELAVPHNDEWTRFARTLVEIRANRADSEEEGTVELSA ::::::::::::::::::::::::::::::::::::::::::::: XP_011 RIWVYDVGELAVPHNDEWTRFARTLVEIRANRADSEEEGTVELSA 610 620 630 640 >>NP_001129029 (OMIM: 603772) cytoplasmic dynein 1 inter (608 aa) initn: 4076 init1: 3416 opt: 3438 Z-score: 2348.2 bits: 444.6 E(85289): 4.7e-124 Smith-Waterman score: 4040; 96.8% identity (96.8% similar) in 628 aa overlap (1-628:1-608) 10 20 30 40 50 60 pF1KB8 MSDKSDLKAELERKKQRLAQIREEKKRKEEERKKKEADMQQKKEPVQDDSDLDRKRRETE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MSDKSDLKAELERKKQRLAQIREEKKRKEEERKKKEADMQQKKEPVQDDSDLDRKRRETE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 ALLQSIGISPEPPLVPTPMSPSSKSVSTPSEAGSQDSGDLGPLTRTLQWDTDPSVLQLQS ::::::::::::::::::::::::::::::::::::::::::::: NP_001 ALLQSIGISPEPPLVPTPMSPSSKSVSTPSEAGSQDSGDLGPLTR--------------- 70 80 90 100 130 140 150 160 170 180 pF1KB8 DSELGRRLHKLGVSKVTQVDFLPREVVSYSKETQTPLATHQSEEDEEDEEMVESKVGQDS ::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 -----RRLHKLGVSKVTQVDFLPREVVSYSKETQTPLATHQSEEDEEDEEMVESKVGQDS 110 120 130 140 150 160 190 200 210 220 230 240 pF1KB8 ELENQDKKQEVKEAPPRELTEEEKQQILHSEEFLIFFDRTIRVIERALAEDSDIFFDYSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ELENQDKKQEVKEAPPRELTEEEKQQILHSEEFLIFFDRTIRVIERALAEDSDIFFDYSG 170 180 190 200 210 220 250 260 270 280 290 300 pF1KB8 RELEEKDGDVQAGANLSFNRQFYDEHWSKHRVVTCMDWSLQYPELMVASYNNNEDAPHEP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RELEEKDGDVQAGANLSFNRQFYDEHWSKHRVVTCMDWSLQYPELMVASYNNNEDAPHEP 230 240 250 260 270 280 310 320 330 340 350 360 pF1KB8 DGVALVWNMKFKKTTPEYVFHCQSSVMSVCFARFHPNLVVGGTYSGQIVLWDNRSHRRTP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DGVALVWNMKFKKTTPEYVFHCQSSVMSVCFARFHPNLVVGGTYSGQIVLWDNRSHRRTP 290 300 310 320 330 340 370 380 390 400 410 420 pF1KB8 VQRTPLSAAAHTHPVYCVNVVGTQNAHNLITVSTDGKMCSWSLDMLSTPQESMELVYNKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VQRTPLSAAAHTHPVYCVNVVGTQNAHNLITVSTDGKMCSWSLDMLSTPQESMELVYNKS 350 360 370 380 390 400 430 440 450 460 470 480 pF1KB8 KPVAVTGMAFPTGDVNNFVVGSEEGTVYTACRHGSKAGIGEVFEGHQGPVTGINCHMAVG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KPVAVTGMAFPTGDVNNFVVGSEEGTVYTACRHGSKAGIGEVFEGHQGPVTGINCHMAVG 410 420 430 440 450 460 490 500 510 520 530 540 pF1KB8 PIDFSHLFVTSSFDWTVKLWTTKHNKPLYSFEDNADYVYDVMWSPVHPALFACVDGMGRL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PIDFSHLFVTSSFDWTVKLWTTKHNKPLYSFEDNADYVYDVMWSPVHPALFACVDGMGRL 470 480 490 500 510 520 550 560 570 580 590 600 pF1KB8 DLWNLNNDTEVPTASVAIEGASALNRVRWAQAGKEVAVGDSEGRIWVYDVGELAVPHNDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DLWNLNNDTEVPTASVAIEGASALNRVRWAQAGKEVAVGDSEGRIWVYDVGELAVPHNDE 530 540 550 560 570 580 610 620 pF1KB8 WTRFARTLVEIRANRADSEEEGTVELSA :::::::::::::::::::::::::::: NP_001 WTRFARTLVEIRANRADSEEEGTVELSA 590 600 >>XP_016867295 (OMIM: 603772) PREDICTED: cytoplasmic dyn (513 aa) initn: 3383 init1: 3383 opt: 3383 Z-score: 2311.9 bits: 437.7 E(85289): 4.9e-122 Smith-Waterman score: 3383; 99.4% identity (99.8% similar) in 507 aa overlap (1-507:1-507) 10 20 30 40 50 60 pF1KB8 MSDKSDLKAELERKKQRLAQIREEKKRKEEERKKKEADMQQKKEPVQDDSDLDRKRRETE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MSDKSDLKAELERKKQRLAQIREEKKRKEEERKKKEADMQQKKEPVQDDSDLDRKRRETE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 ALLQSIGISPEPPLVPTPMSPSSKSVSTPSEAGSQDSGDLGPLTRTLQWDTDPSVLQLQS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ALLQSIGISPEPPLVPTPMSPSSKSVSTPSEAGSQDSGDLGPLTRTLQWDTDPSVLQLQS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 DSELGRRLHKLGVSKVTQVDFLPREVVSYSKETQTPLATHQSEEDEEDEEMVESKVGQDS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DSELGRRLHKLGVSKVTQVDFLPREVVSYSKETQTPLATHQSEEDEEDEEMVESKVGQDS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 ELENQDKKQEVKEAPPRELTEEEKQQILHSEEFLIFFDRTIRVIERALAEDSDIFFDYSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ELENQDKKQEVKEAPPRELTEEEKQQILHSEEFLIFFDRTIRVIERALAEDSDIFFDYSG 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 RELEEKDGDVQAGANLSFNRQFYDEHWSKHRVVTCMDWSLQYPELMVASYNNNEDAPHEP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RELEEKDGDVQAGANLSFNRQFYDEHWSKHRVVTCMDWSLQYPELMVASYNNNEDAPHEP 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 DGVALVWNMKFKKTTPEYVFHCQSSVMSVCFARFHPNLVVGGTYSGQIVLWDNRSHRRTP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DGVALVWNMKFKKTTPEYVFHCQSSVMSVCFARFHPNLVVGGTYSGQIVLWDNRSHRRTP 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB8 VQRTPLSAAAHTHPVYCVNVVGTQNAHNLITVSTDGKMCSWSLDMLSTPQESMELVYNKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VQRTPLSAAAHTHPVYCVNVVGTQNAHNLITVSTDGKMCSWSLDMLSTPQESMELVYNKS 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB8 KPVAVTGMAFPTGDVNNFVVGSEEGTVYTACRHGSKAGIGEVFEGHQGPVTGINCHMAVG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KPVAVTGMAFPTGDVNNFVVGSEEGTVYTACRHGSKAGIGEVFEGHQGPVTGINCHMAVG 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB8 PIDFSHLFVTSSFDWTVKLWTTKHNKPLYSFEDNADYVYDVMWSPVHPALFACVDGMGRL :::::::::::::::::::::::.. : XP_016 PIDFSHLFVTSSFDWTVKLWTTKESMPKIYQQK 490 500 510 >>XP_006712410 (OMIM: 603331) PREDICTED: cytoplasmic dyn (631 aa) initn: 3240 init1: 2560 opt: 3382 Z-score: 2310.0 bits: 437.6 E(85289): 6.3e-122 Smith-Waterman score: 3382; 77.4% identity (93.4% similar) in 633 aa overlap (1-628:1-631) 10 20 30 40 50 pF1KB8 MSDKSDLKAELERKKQRLAQIREEKKRKEEERKKKEADMQQKKE---PVQDDSDLDRKRR :::::.::::::::::::::::::::::::::::::.: :::: :::..:::..::: XP_006 MSDKSELKAELERKKQRLAQIREEKKRKEEERKKKETD--QKKEAVAPVQEESDLEKKRR 10 20 30 40 50 60 70 80 90 100 110 pF1KB8 ETEALLQSIGISPEPPLVPTPMSPSSKSVSTPSEAGSQDSGDLGPLTRTLQWDTDPSVLQ :.::::::.:..:: :.:: :::::::::::::::::::::: . .:::.::::::::: XP_006 EAEALLQSMGLTPESPIVPPPMSPSSKSVSTPSEAGSQDSGDGAVGSRTLHWDTDPSVLQ 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB8 LQSDSELGRRLHKLGVSKVTQVDFLPREVVSYSKETQTPLATHQSEEDEEDEEMVESKVG :.:::.::: :::..:.::::: :::.:.:.::::::. .. .:..:::...: : XP_006 LHSDSDLGRGPIKLGMAKITQVDFPPREIVTYTKETQTPVMAQPKEDEEEDDDVVAPKPP 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB8 QDSELENQDKKQEVKE--APPRELTEEEKQQILHSEEFLIFFDRTIRVIERALAEDSDIF . : :. ::.: .. :::.::::::::::::::::: :::.. :..::::.:. .:: XP_006 IEPEEEKTLKKDEENDSKAPPHELTEEEKQQILHSEEFLSFFDHSTRIVERALSEQINIF 180 190 200 210 220 230 240 250 260 270 280 290 pF1KB8 FDYSGRELEEKDGDVQAGANLSFNRQFYDEHWSKHRVVTCMDWSLQYPELMVASYNNNED ::::::.::.:.:..::::.::.::::.::.:::::::.:.::: :::::.::::::::: XP_006 FDYSGRDLEDKEGEIQAGAKLSLNRQFFDERWSKHRVVSCLDWSSQYPELLVASYNNNED 240 250 260 270 280 290 300 310 320 330 340 350 pF1KB8 APHEPDGVALVWNMKFKKTTPEYVFHCQSSVMSVCFARFHPNLVVGGTYSGQIVLWDNRS :::::::::::::::.:::::::::::::.:::. ::.:::::::::::::::::::::: XP_006 APHEPDGVALVWNMKYKKTTPEYVFHCQSAVMSATFAKFHPNLVVGGTYSGQIVLWDNRS 300 310 320 330 340 350 360 370 380 390 400 410 pF1KB8 HRRTPVQRTPLSAAAHTHPVYCVNVVGTQNAHNLITVSTDGKMCSWSLDMLSTPQESMEL ..:::::::::::::::::::::::::::::::::..:::::.::::::::: ::.:::: XP_006 NKRTPVQRTPLSAAAHTHPVYCVNVVGTQNAHNLISISTDGKICSWSLDMLSHPQDSMEL 360 370 380 390 400 410 420 430 440 450 460 470 pF1KB8 VYNKSKPVAVTGMAFPTGDVNNFVVGSEEGTVYTACRHGSKAGIGEVFEGHQGPVTGINC :...:: ::::.:.::.:::::::::::::.:::::::::::::.:.:::::::.:::.: XP_006 VHKQSKAVAVTSMSFPVGDVNNFVVGSEEGSVYTACRHGSKAGISEMFEGHQGPITGIHC 420 430 440 450 460 470 480 490 500 510 520 530 pF1KB8 HMAVGPIDFSHLFVTSSFDWTVKLWTTKHNKPLYSFEDNADYVYDVMWSPVHPALFACVD : ::: .:::::::::::::::::::::.:::::::::::::::::::::.::::::::: XP_006 HAAVGAVDFSHLFVTSSFDWTVKLWTTKNNKPLYSFEDNADYVYDVMWSPTHPALFACVD 480 490 500 510 520 530 540 550 560 570 580 590 pF1KB8 GMGRLDLWNLNNDTEVPTASVAIEGASALNRVRWAQAGKEVAVGDSEGRIWVYDVGELAV ::::::::::::::::::::...:: :::::::...:.:.:::::::.: .:::::.:: XP_006 GMGRLDLWNLNNDTEVPTASISVEGNPALNRVRWTHSGREIAVGDSEGQIVIYDVGEIAV 540 550 560 570 580 590 600 610 620 pF1KB8 PHNDEWTRFARTLVEIRANRADSEEEGTVELSA :.::::.::.:::.:: :::::.:::..... : XP_006 PRNDEWARFGRTLAEINANRADAEEEAATRIPA 600 610 620 630 628 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 12:21:22 2016 done: Fri Nov 4 12:21:24 2016 Total Scan time: 11.930 Total Display time: 0.140 Function used was FASTA [36.3.4 Apr, 2011]