FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB8377, 622 aa 1>>>pF1KB8377 622 - 622 aa - 622 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.4961+/-0.000291; mu= 14.2116+/- 0.018 mean_var=87.5115+/-17.933, 0's: 0 Z-trim(119.8): 5 B-trim: 1762 in 1/53 Lambda= 0.137101 statistics sampled from 34152 (34157) to 34152 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.743), E-opt: 0.2 (0.4), width: 16 Scan time: 12.890 The best scores are: opt bits E(85289) NP_004620 (OMIM: 189960,602956,614082) Fanconi ane ( 622) 4117 824.0 0 >>NP_004620 (OMIM: 189960,602956,614082) Fanconi anemia (622 aa) initn: 4117 init1: 4117 opt: 4117 Z-score: 4398.2 bits: 824.0 E(85289): 0 Smith-Waterman score: 4117; 100.0% identity (100.0% similar) in 622 aa overlap (1-622:1-622) 10 20 30 40 50 60 pF1KB8 MSRQTTSVGSSCLDLWREKNDRLVRQAKVAQNSGLTLRRQQLAQDALEGLRGLLHSLQGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 MSRQTTSVGSSCLDLWREKNDRLVRQAKVAQNSGLTLRRQQLAQDALEGLRGLLHSLQGL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 PAAVPVLPLELTVTCNFIILRASLAQGFTEDQAQDIQRSLERVLETQEQQGPRLEQGLRE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 PAAVPVLPLELTVTCNFIILRASLAQGFTEDQAQDIQRSLERVLETQEQQGPRLEQGLRE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 LWDSVLRASCLLPELLSALHRLVGLQAALWLSADRLGDLALLLETLNGSQSGASKDLLLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 LWDSVLRASCLLPELLSALHRLVGLQAALWLSADRLGDLALLLETLNGSQSGASKDLLLL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 LKTWSPPAEELDAPLTLQDAQGLKDVLLTAFAYRQGLQELITGNPDKALSSLHEAASGLC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 LKTWSPPAEELDAPLTLQDAQGLKDVLLTAFAYRQGLQELITGNPDKALSSLHEAASGLC 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 PRPVLVQVYTALGSCHRKMGNPQRALLYLVAALKEGSAWGPPLLEASRLYQQLGDTTAEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 PRPVLVQVYTALGSCHRKMGNPQRALLYLVAALKEGSAWGPPLLEASRLYQQLGDTTAEL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 ESLELLVEALNVPCSSKAPQFLIEVELLLPPPDLASPLHCGTQSQTKHILASRCLQTGRA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 ESLELLVEALNVPCSSKAPQFLIEVELLLPPPDLASPLHCGTQSQTKHILASRCLQTGRA 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB8 GDAAEHYLDLLALLLDSSEPRFSPPPSPPGPCMPEVFLEAAVALIQAGRAQDALTLCEEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 GDAAEHYLDLLALLLDSSEPRFSPPPSPPGPCMPEVFLEAAVALIQAGRAQDALTLCEEL 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB8 LSRTSSLLPKMSRLWEDARKGTKELPYCPLWVSATHLLQGQAWVQLGAQKVAISEFSRCL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 LSRTSSLLPKMSRLWEDARKGTKELPYCPLWVSATHLLQGQAWVQLGAQKVAISEFSRCL 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB8 ELLFRATPEEKEQGAAFNCEQGCKSDAALQQLRAAALISRGLEWVASGQDTKALQDFLLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 ELLFRATPEEKEQGAAFNCEQGCKSDAALQQLRAAALISRGLEWVASGQDTKALQDFLLS 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB8 VQMCPGNRDTYFHLLQTLKRLDRRDEATALWWRLEAQTKGSHEDALWSLPLYLESYLSWI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 VQMCPGNRDTYFHLLQTLKRLDRRDEATALWWRLEAQTKGSHEDALWSLPLYLESYLSWI 550 560 570 580 590 600 610 620 pF1KB8 RPSDRDAFLEEFRTSLPKSCDL :::::::::::::::::::::: NP_004 RPSDRDAFLEEFRTSLPKSCDL 610 620 622 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 12:23:17 2016 done: Fri Nov 4 12:23:19 2016 Total Scan time: 12.890 Total Display time: -0.030 Function used was FASTA [36.3.4 Apr, 2011]