FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB8379, 614 aa 1>>>pF1KB8379 614 - 614 aa - 614 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.4850+/-0.000309; mu= 19.2647+/- 0.019 mean_var=85.5012+/-17.418, 0's: 0 Z-trim(118.0): 111 B-trim: 468 in 1/55 Lambda= 0.138704 statistics sampled from 30372 (30492) to 30372 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.71), E-opt: 0.2 (0.358), width: 16 Scan time: 10.970 The best scores are: opt bits E(85289) NP_000656 (OMIM: 100740,112100) acetylcholinestera ( 614) 4275 865.4 0 NP_001289551 (OMIM: 100740,112100) acetylcholinest ( 614) 4275 865.4 0 XP_016867708 (OMIM: 100740,112100) PREDICTED: acet ( 780) 4275 865.5 0 XP_006716058 (OMIM: 100740,112100) PREDICTED: acet ( 617) 3973 805.0 0 XP_011514531 (OMIM: 100740,112100) PREDICTED: acet ( 617) 3973 805.0 0 NP_056646 (OMIM: 100740,112100) acetylcholinestera ( 617) 3973 805.0 0 XP_011514530 (OMIM: 100740,112100) PREDICTED: acet ( 617) 3973 805.0 0 NP_001289550 (OMIM: 100740,112100) acetylcholinest ( 617) 3973 805.0 0 XP_011514527 (OMIM: 100740,112100) PREDICTED: acet ( 783) 3973 805.0 0 NP_001269378 (OMIM: 100740,112100) acetylcholinest ( 526) 2487 507.6 4.5e-143 XP_016867709 (OMIM: 100740,112100) PREDICTED: acet ( 692) 2487 507.6 5.5e-143 XP_011514528 (OMIM: 100740,112100) PREDICTED: acet ( 695) 2487 507.6 5.5e-143 NP_000046 (OMIM: 177400) cholinesterase precursor ( 602) 2248 459.8 1.2e-128 XP_016862456 (OMIM: 177400) PREDICTED: cholinester ( 643) 2248 459.8 1.3e-128 NP_001798 (OMIM: 114840,609812) bile salt-activate ( 756) 968 203.7 1.9e-51 NP_001020366 (OMIM: 114835) liver carboxylesterase ( 568) 930 196.0 2.9e-49 NP_001020365 (OMIM: 114835) liver carboxylesterase ( 567) 927 195.4 4.4e-49 XP_005255831 (OMIM: 114835) PREDICTED: liver carbo ( 567) 926 195.2 5.1e-49 NP_001257 (OMIM: 114835) liver carboxylesterase 1 ( 566) 923 194.6 7.7e-49 NP_001160132 (OMIM: 300336,300425,300494) neurolig ( 808) 848 179.7 3.3e-44 XP_005256801 (OMIM: 606479) PREDICTED: neuroligin- ( 818) 761 162.3 5.9e-39 XP_005247294 (OMIM: 600568) PREDICTED: neuroligin- ( 671) 741 158.2 8.1e-38 XP_016869286 (OMIM: 188450,274700,608175) PREDICTE (2681) 740 158.5 2.7e-37 XP_016869285 (OMIM: 188450,274700,608175) PREDICTE (2695) 740 158.5 2.7e-37 XP_005251095 (OMIM: 188450,274700,608175) PREDICTE (2704) 740 158.5 2.7e-37 XP_016869284 (OMIM: 188450,274700,608175) PREDICTE (2711) 740 158.5 2.7e-37 XP_016869282 (OMIM: 188450,274700,608175) PREDICTE (2746) 740 158.5 2.7e-37 XP_006716685 (OMIM: 188450,274700,608175) PREDICTE (2747) 740 158.5 2.7e-37 NP_003226 (OMIM: 188450,274700,608175) thyroglobul (2768) 740 158.5 2.7e-37 NP_932327 (OMIM: 605278) cocaine esterase isoform ( 607) 722 154.4 1e-36 NP_003860 (OMIM: 605278) cocaine esterase isoform ( 623) 722 154.4 1.1e-36 NP_079198 (OMIM: 605279) carboxylesterase 3 isofor ( 571) 692 148.4 6.4e-35 XP_011521277 (OMIM: 605279) PREDICTED: carboxylest ( 547) 685 147.0 1.6e-34 XP_011521278 (OMIM: 605279) PREDICTED: carboxylest ( 402) 683 146.5 1.7e-34 NP_001172106 (OMIM: 605279) carboxylesterase 3 iso ( 568) 683 146.6 2.2e-34 XP_016885523 (OMIM: 400028) PREDICTED: neuroligin- ( 816) 622 134.5 1.4e-30 NP_065793 (OMIM: 300427,300495,300497) neuroligin- ( 816) 622 134.5 1.4e-30 XP_016885181 (OMIM: 300427,300495,300497) PREDICTE ( 816) 622 134.5 1.4e-30 XP_016885524 (OMIM: 400028) PREDICTED: neuroligin- ( 816) 622 134.5 1.4e-30 XP_016885180 (OMIM: 300427,300495,300497) PREDICTE ( 816) 622 134.5 1.4e-30 XP_016885527 (OMIM: 400028) PREDICTED: neuroligin- ( 816) 622 134.5 1.4e-30 NP_055708 (OMIM: 400028) neuroligin-4, Y-linked is ( 816) 622 134.5 1.4e-30 XP_016885182 (OMIM: 300427,300495,300497) PREDICTE ( 816) 622 134.5 1.4e-30 NP_851849 (OMIM: 300427,300495,300497) neuroligin- ( 816) 622 134.5 1.4e-30 NP_001269075 (OMIM: 300427,300495,300497) neurolig ( 816) 622 134.5 1.4e-30 XP_016885525 (OMIM: 400028) PREDICTED: neuroligin- ( 816) 622 134.5 1.4e-30 NP_001269074 (OMIM: 300427,300495,300497) neurolig ( 816) 622 134.5 1.4e-30 XP_016885526 (OMIM: 400028) PREDICTED: neuroligin- ( 816) 622 134.5 1.4e-30 XP_016861391 (OMIM: 600568) PREDICTED: neuroligin- ( 814) 614 132.9 4.2e-30 XP_016861392 (OMIM: 600568) PREDICTED: neuroligin- ( 814) 614 132.9 4.2e-30 >>NP_000656 (OMIM: 100740,112100) acetylcholinesterase i (614 aa) initn: 4275 init1: 4275 opt: 4275 Z-score: 4622.4 bits: 865.4 E(85289): 0 Smith-Waterman score: 4275; 100.0% identity (100.0% similar) in 614 aa overlap (1-614:1-614) 10 20 30 40 50 60 pF1KB8 MRPPQCLLHTPSLASPLLLLLLWLLGGGVGAEGREDAELLVTVRGGRLRGIRLKTPGGPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 MRPPQCLLHTPSLASPLLLLLLWLLGGGVGAEGREDAELLVTVRGGRLRGIRLKTPGGPV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 SAFLGIPFAEPPMGPRRFLPPEPKQPWSGVVDATTFQSVCYQYVDTLYPGFEGTEMWNPN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 SAFLGIPFAEPPMGPRRFLPPEPKQPWSGVVDATTFQSVCYQYVDTLYPGFEGTEMWNPN 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 RELSEDCLYLNVWTPYPRPTSPTPVLVWIYGGGFYSGASSLDVYDGRFLVQAERTVLVSM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 RELSEDCLYLNVWTPYPRPTSPTPVLVWIYGGGFYSGASSLDVYDGRFLVQAERTVLVSM 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 NYRVGAFGFLALPGSREAPGNVGLLDQRLALQWVQENVAAFGGDPTSVTLFGESAGAASV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 NYRVGAFGFLALPGSREAPGNVGLLDQRLALQWVQENVAAFGGDPTSVTLFGESAGAASV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 GMHLLSPPSRGLFHRAVLQSGAPNGPWATVGMGEARRRATQLAHLVGCPPGGTGGNDTEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 GMHLLSPPSRGLFHRAVLQSGAPNGPWATVGMGEARRRATQLAHLVGCPPGGTGGNDTEL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 VACLRTRPAQVLVNHEWHVLPQESVFRFSFVPVVDGDFLSDTPEALINAGDFHGLQVLVG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 VACLRTRPAQVLVNHEWHVLPQESVFRFSFVPVVDGDFLSDTPEALINAGDFHGLQVLVG 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB8 VVKDEGSYFLVYGAPGFSKDNESLISRAEFLAGVRVGVPQVSDLAAEAVVLHYTDWLHPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 VVKDEGSYFLVYGAPGFSKDNESLISRAEFLAGVRVGVPQVSDLAAEAVVLHYTDWLHPE 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB8 DPARLREALSDVVGDHNVVCPVAQLAGRLAAQGARVYAYVFEHRASTLSWPLWMGVPHGY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 DPARLREALSDVVGDHNVVCPVAQLAGRLAAQGARVYAYVFEHRASTLSWPLWMGVPHGY 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB8 EIEFIFGIPLDPSRNYTAEEKIFAQRLMRYWANFARTGDPNEPRDPKAPQWPPYTAGAQQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 EIEFIFGIPLDPSRNYTAEEKIFAQRLMRYWANFARTGDPNEPRDPKAPQWPPYTAGAQQ 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB8 YVSLDLRPLEVRRGLRAQACAFWNRFLPKLLSATDTLDEAERQWKAEFHRWSSYMVHWKN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 YVSLDLRPLEVRRGLRAQACAFWNRFLPKLLSATDTLDEAERQWKAEFHRWSSYMVHWKN 550 560 570 580 590 600 610 pF1KB8 QFDHYSKQDRCSDL :::::::::::::: NP_000 QFDHYSKQDRCSDL 610 >>NP_001289551 (OMIM: 100740,112100) acetylcholinesteras (614 aa) initn: 4275 init1: 4275 opt: 4275 Z-score: 4622.4 bits: 865.4 E(85289): 0 Smith-Waterman score: 4275; 100.0% identity (100.0% similar) in 614 aa overlap (1-614:1-614) 10 20 30 40 50 60 pF1KB8 MRPPQCLLHTPSLASPLLLLLLWLLGGGVGAEGREDAELLVTVRGGRLRGIRLKTPGGPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MRPPQCLLHTPSLASPLLLLLLWLLGGGVGAEGREDAELLVTVRGGRLRGIRLKTPGGPV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 SAFLGIPFAEPPMGPRRFLPPEPKQPWSGVVDATTFQSVCYQYVDTLYPGFEGTEMWNPN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SAFLGIPFAEPPMGPRRFLPPEPKQPWSGVVDATTFQSVCYQYVDTLYPGFEGTEMWNPN 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 RELSEDCLYLNVWTPYPRPTSPTPVLVWIYGGGFYSGASSLDVYDGRFLVQAERTVLVSM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RELSEDCLYLNVWTPYPRPTSPTPVLVWIYGGGFYSGASSLDVYDGRFLVQAERTVLVSM 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 NYRVGAFGFLALPGSREAPGNVGLLDQRLALQWVQENVAAFGGDPTSVTLFGESAGAASV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NYRVGAFGFLALPGSREAPGNVGLLDQRLALQWVQENVAAFGGDPTSVTLFGESAGAASV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 GMHLLSPPSRGLFHRAVLQSGAPNGPWATVGMGEARRRATQLAHLVGCPPGGTGGNDTEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GMHLLSPPSRGLFHRAVLQSGAPNGPWATVGMGEARRRATQLAHLVGCPPGGTGGNDTEL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 VACLRTRPAQVLVNHEWHVLPQESVFRFSFVPVVDGDFLSDTPEALINAGDFHGLQVLVG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VACLRTRPAQVLVNHEWHVLPQESVFRFSFVPVVDGDFLSDTPEALINAGDFHGLQVLVG 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB8 VVKDEGSYFLVYGAPGFSKDNESLISRAEFLAGVRVGVPQVSDLAAEAVVLHYTDWLHPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VVKDEGSYFLVYGAPGFSKDNESLISRAEFLAGVRVGVPQVSDLAAEAVVLHYTDWLHPE 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB8 DPARLREALSDVVGDHNVVCPVAQLAGRLAAQGARVYAYVFEHRASTLSWPLWMGVPHGY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DPARLREALSDVVGDHNVVCPVAQLAGRLAAQGARVYAYVFEHRASTLSWPLWMGVPHGY 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB8 EIEFIFGIPLDPSRNYTAEEKIFAQRLMRYWANFARTGDPNEPRDPKAPQWPPYTAGAQQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EIEFIFGIPLDPSRNYTAEEKIFAQRLMRYWANFARTGDPNEPRDPKAPQWPPYTAGAQQ 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB8 YVSLDLRPLEVRRGLRAQACAFWNRFLPKLLSATDTLDEAERQWKAEFHRWSSYMVHWKN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YVSLDLRPLEVRRGLRAQACAFWNRFLPKLLSATDTLDEAERQWKAEFHRWSSYMVHWKN 550 560 570 580 590 600 610 pF1KB8 QFDHYSKQDRCSDL :::::::::::::: NP_001 QFDHYSKQDRCSDL 610 >>XP_016867708 (OMIM: 100740,112100) PREDICTED: acetylch (780 aa) initn: 4275 init1: 4275 opt: 4275 Z-score: 4621.0 bits: 865.5 E(85289): 0 Smith-Waterman score: 4275; 100.0% identity (100.0% similar) in 614 aa overlap (1-614:167-780) 10 20 30 pF1KB8 MRPPQCLLHTPSLASPLLLLLLWLLGGGVG :::::::::::::::::::::::::::::: XP_016 SALISSLLASRPTLHPFPFFLPADAACPAAMRPPQCLLHTPSLASPLLLLLLWLLGGGVG 140 150 160 170 180 190 40 50 60 70 80 90 pF1KB8 AEGREDAELLVTVRGGRLRGIRLKTPGGPVSAFLGIPFAEPPMGPRRFLPPEPKQPWSGV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AEGREDAELLVTVRGGRLRGIRLKTPGGPVSAFLGIPFAEPPMGPRRFLPPEPKQPWSGV 200 210 220 230 240 250 100 110 120 130 140 150 pF1KB8 VDATTFQSVCYQYVDTLYPGFEGTEMWNPNRELSEDCLYLNVWTPYPRPTSPTPVLVWIY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VDATTFQSVCYQYVDTLYPGFEGTEMWNPNRELSEDCLYLNVWTPYPRPTSPTPVLVWIY 260 270 280 290 300 310 160 170 180 190 200 210 pF1KB8 GGGFYSGASSLDVYDGRFLVQAERTVLVSMNYRVGAFGFLALPGSREAPGNVGLLDQRLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GGGFYSGASSLDVYDGRFLVQAERTVLVSMNYRVGAFGFLALPGSREAPGNVGLLDQRLA 320 330 340 350 360 370 220 230 240 250 260 270 pF1KB8 LQWVQENVAAFGGDPTSVTLFGESAGAASVGMHLLSPPSRGLFHRAVLQSGAPNGPWATV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LQWVQENVAAFGGDPTSVTLFGESAGAASVGMHLLSPPSRGLFHRAVLQSGAPNGPWATV 380 390 400 410 420 430 280 290 300 310 320 330 pF1KB8 GMGEARRRATQLAHLVGCPPGGTGGNDTELVACLRTRPAQVLVNHEWHVLPQESVFRFSF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GMGEARRRATQLAHLVGCPPGGTGGNDTELVACLRTRPAQVLVNHEWHVLPQESVFRFSF 440 450 460 470 480 490 340 350 360 370 380 390 pF1KB8 VPVVDGDFLSDTPEALINAGDFHGLQVLVGVVKDEGSYFLVYGAPGFSKDNESLISRAEF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VPVVDGDFLSDTPEALINAGDFHGLQVLVGVVKDEGSYFLVYGAPGFSKDNESLISRAEF 500 510 520 530 540 550 400 410 420 430 440 450 pF1KB8 LAGVRVGVPQVSDLAAEAVVLHYTDWLHPEDPARLREALSDVVGDHNVVCPVAQLAGRLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LAGVRVGVPQVSDLAAEAVVLHYTDWLHPEDPARLREALSDVVGDHNVVCPVAQLAGRLA 560 570 580 590 600 610 460 470 480 490 500 510 pF1KB8 AQGARVYAYVFEHRASTLSWPLWMGVPHGYEIEFIFGIPLDPSRNYTAEEKIFAQRLMRY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AQGARVYAYVFEHRASTLSWPLWMGVPHGYEIEFIFGIPLDPSRNYTAEEKIFAQRLMRY 620 630 640 650 660 670 520 530 540 550 560 570 pF1KB8 WANFARTGDPNEPRDPKAPQWPPYTAGAQQYVSLDLRPLEVRRGLRAQACAFWNRFLPKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 WANFARTGDPNEPRDPKAPQWPPYTAGAQQYVSLDLRPLEVRRGLRAQACAFWNRFLPKL 680 690 700 710 720 730 580 590 600 610 pF1KB8 LSATDTLDEAERQWKAEFHRWSSYMVHWKNQFDHYSKQDRCSDL :::::::::::::::::::::::::::::::::::::::::::: XP_016 LSATDTLDEAERQWKAEFHRWSSYMVHWKNQFDHYSKQDRCSDL 740 750 760 770 780 >>XP_006716058 (OMIM: 100740,112100) PREDICTED: acetylch (617 aa) initn: 3973 init1: 3973 opt: 3973 Z-score: 4295.7 bits: 805.0 E(85289): 0 Smith-Waterman score: 3973; 100.0% identity (100.0% similar) in 574 aa overlap (1-574:1-574) 10 20 30 40 50 60 pF1KB8 MRPPQCLLHTPSLASPLLLLLLWLLGGGVGAEGREDAELLVTVRGGRLRGIRLKTPGGPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 MRPPQCLLHTPSLASPLLLLLLWLLGGGVGAEGREDAELLVTVRGGRLRGIRLKTPGGPV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 SAFLGIPFAEPPMGPRRFLPPEPKQPWSGVVDATTFQSVCYQYVDTLYPGFEGTEMWNPN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 SAFLGIPFAEPPMGPRRFLPPEPKQPWSGVVDATTFQSVCYQYVDTLYPGFEGTEMWNPN 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 RELSEDCLYLNVWTPYPRPTSPTPVLVWIYGGGFYSGASSLDVYDGRFLVQAERTVLVSM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 RELSEDCLYLNVWTPYPRPTSPTPVLVWIYGGGFYSGASSLDVYDGRFLVQAERTVLVSM 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 NYRVGAFGFLALPGSREAPGNVGLLDQRLALQWVQENVAAFGGDPTSVTLFGESAGAASV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 NYRVGAFGFLALPGSREAPGNVGLLDQRLALQWVQENVAAFGGDPTSVTLFGESAGAASV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 GMHLLSPPSRGLFHRAVLQSGAPNGPWATVGMGEARRRATQLAHLVGCPPGGTGGNDTEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 GMHLLSPPSRGLFHRAVLQSGAPNGPWATVGMGEARRRATQLAHLVGCPPGGTGGNDTEL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 VACLRTRPAQVLVNHEWHVLPQESVFRFSFVPVVDGDFLSDTPEALINAGDFHGLQVLVG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 VACLRTRPAQVLVNHEWHVLPQESVFRFSFVPVVDGDFLSDTPEALINAGDFHGLQVLVG 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB8 VVKDEGSYFLVYGAPGFSKDNESLISRAEFLAGVRVGVPQVSDLAAEAVVLHYTDWLHPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 VVKDEGSYFLVYGAPGFSKDNESLISRAEFLAGVRVGVPQVSDLAAEAVVLHYTDWLHPE 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB8 DPARLREALSDVVGDHNVVCPVAQLAGRLAAQGARVYAYVFEHRASTLSWPLWMGVPHGY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 DPARLREALSDVVGDHNVVCPVAQLAGRLAAQGARVYAYVFEHRASTLSWPLWMGVPHGY 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB8 EIEFIFGIPLDPSRNYTAEEKIFAQRLMRYWANFARTGDPNEPRDPKAPQWPPYTAGAQQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 EIEFIFGIPLDPSRNYTAEEKIFAQRLMRYWANFARTGDPNEPRDPKAPQWPPYTAGAQQ 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB8 YVSLDLRPLEVRRGLRAQACAFWNRFLPKLLSATDTLDEAERQWKAEFHRWSSYMVHWKN :::::::::::::::::::::::::::::::::: XP_006 YVSLDLRPLEVRRGLRAQACAFWNRFLPKLLSATASEAPSTCPGFTHGEAAPRPGLPLPL 550 560 570 580 590 600 610 pF1KB8 QFDHYSKQDRCSDL XP_006 LLLHQLLLLFLSHLRRL 610 >>XP_011514531 (OMIM: 100740,112100) PREDICTED: acetylch (617 aa) initn: 3973 init1: 3973 opt: 3973 Z-score: 4295.7 bits: 805.0 E(85289): 0 Smith-Waterman score: 3973; 100.0% identity (100.0% similar) in 574 aa overlap (1-574:1-574) 10 20 30 40 50 60 pF1KB8 MRPPQCLLHTPSLASPLLLLLLWLLGGGVGAEGREDAELLVTVRGGRLRGIRLKTPGGPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MRPPQCLLHTPSLASPLLLLLLWLLGGGVGAEGREDAELLVTVRGGRLRGIRLKTPGGPV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 SAFLGIPFAEPPMGPRRFLPPEPKQPWSGVVDATTFQSVCYQYVDTLYPGFEGTEMWNPN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SAFLGIPFAEPPMGPRRFLPPEPKQPWSGVVDATTFQSVCYQYVDTLYPGFEGTEMWNPN 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 RELSEDCLYLNVWTPYPRPTSPTPVLVWIYGGGFYSGASSLDVYDGRFLVQAERTVLVSM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RELSEDCLYLNVWTPYPRPTSPTPVLVWIYGGGFYSGASSLDVYDGRFLVQAERTVLVSM 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 NYRVGAFGFLALPGSREAPGNVGLLDQRLALQWVQENVAAFGGDPTSVTLFGESAGAASV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NYRVGAFGFLALPGSREAPGNVGLLDQRLALQWVQENVAAFGGDPTSVTLFGESAGAASV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 GMHLLSPPSRGLFHRAVLQSGAPNGPWATVGMGEARRRATQLAHLVGCPPGGTGGNDTEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GMHLLSPPSRGLFHRAVLQSGAPNGPWATVGMGEARRRATQLAHLVGCPPGGTGGNDTEL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 VACLRTRPAQVLVNHEWHVLPQESVFRFSFVPVVDGDFLSDTPEALINAGDFHGLQVLVG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VACLRTRPAQVLVNHEWHVLPQESVFRFSFVPVVDGDFLSDTPEALINAGDFHGLQVLVG 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB8 VVKDEGSYFLVYGAPGFSKDNESLISRAEFLAGVRVGVPQVSDLAAEAVVLHYTDWLHPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VVKDEGSYFLVYGAPGFSKDNESLISRAEFLAGVRVGVPQVSDLAAEAVVLHYTDWLHPE 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB8 DPARLREALSDVVGDHNVVCPVAQLAGRLAAQGARVYAYVFEHRASTLSWPLWMGVPHGY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DPARLREALSDVVGDHNVVCPVAQLAGRLAAQGARVYAYVFEHRASTLSWPLWMGVPHGY 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB8 EIEFIFGIPLDPSRNYTAEEKIFAQRLMRYWANFARTGDPNEPRDPKAPQWPPYTAGAQQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EIEFIFGIPLDPSRNYTAEEKIFAQRLMRYWANFARTGDPNEPRDPKAPQWPPYTAGAQQ 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB8 YVSLDLRPLEVRRGLRAQACAFWNRFLPKLLSATDTLDEAERQWKAEFHRWSSYMVHWKN :::::::::::::::::::::::::::::::::: XP_011 YVSLDLRPLEVRRGLRAQACAFWNRFLPKLLSATASEAPSTCPGFTHGEAAPRPGLPLPL 550 560 570 580 590 600 610 pF1KB8 QFDHYSKQDRCSDL XP_011 LLLHQLLLLFLSHLRRL 610 >>NP_056646 (OMIM: 100740,112100) acetylcholinesterase i (617 aa) initn: 3973 init1: 3973 opt: 3973 Z-score: 4295.7 bits: 805.0 E(85289): 0 Smith-Waterman score: 3973; 100.0% identity (100.0% similar) in 574 aa overlap (1-574:1-574) 10 20 30 40 50 60 pF1KB8 MRPPQCLLHTPSLASPLLLLLLWLLGGGVGAEGREDAELLVTVRGGRLRGIRLKTPGGPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 MRPPQCLLHTPSLASPLLLLLLWLLGGGVGAEGREDAELLVTVRGGRLRGIRLKTPGGPV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 SAFLGIPFAEPPMGPRRFLPPEPKQPWSGVVDATTFQSVCYQYVDTLYPGFEGTEMWNPN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 SAFLGIPFAEPPMGPRRFLPPEPKQPWSGVVDATTFQSVCYQYVDTLYPGFEGTEMWNPN 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 RELSEDCLYLNVWTPYPRPTSPTPVLVWIYGGGFYSGASSLDVYDGRFLVQAERTVLVSM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 RELSEDCLYLNVWTPYPRPTSPTPVLVWIYGGGFYSGASSLDVYDGRFLVQAERTVLVSM 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 NYRVGAFGFLALPGSREAPGNVGLLDQRLALQWVQENVAAFGGDPTSVTLFGESAGAASV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 NYRVGAFGFLALPGSREAPGNVGLLDQRLALQWVQENVAAFGGDPTSVTLFGESAGAASV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 GMHLLSPPSRGLFHRAVLQSGAPNGPWATVGMGEARRRATQLAHLVGCPPGGTGGNDTEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 GMHLLSPPSRGLFHRAVLQSGAPNGPWATVGMGEARRRATQLAHLVGCPPGGTGGNDTEL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 VACLRTRPAQVLVNHEWHVLPQESVFRFSFVPVVDGDFLSDTPEALINAGDFHGLQVLVG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 VACLRTRPAQVLVNHEWHVLPQESVFRFSFVPVVDGDFLSDTPEALINAGDFHGLQVLVG 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB8 VVKDEGSYFLVYGAPGFSKDNESLISRAEFLAGVRVGVPQVSDLAAEAVVLHYTDWLHPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 VVKDEGSYFLVYGAPGFSKDNESLISRAEFLAGVRVGVPQVSDLAAEAVVLHYTDWLHPE 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB8 DPARLREALSDVVGDHNVVCPVAQLAGRLAAQGARVYAYVFEHRASTLSWPLWMGVPHGY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 DPARLREALSDVVGDHNVVCPVAQLAGRLAAQGARVYAYVFEHRASTLSWPLWMGVPHGY 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB8 EIEFIFGIPLDPSRNYTAEEKIFAQRLMRYWANFARTGDPNEPRDPKAPQWPPYTAGAQQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 EIEFIFGIPLDPSRNYTAEEKIFAQRLMRYWANFARTGDPNEPRDPKAPQWPPYTAGAQQ 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB8 YVSLDLRPLEVRRGLRAQACAFWNRFLPKLLSATDTLDEAERQWKAEFHRWSSYMVHWKN :::::::::::::::::::::::::::::::::: NP_056 YVSLDLRPLEVRRGLRAQACAFWNRFLPKLLSATASEAPSTCPGFTHGEAAPRPGLPLPL 550 560 570 580 590 600 610 pF1KB8 QFDHYSKQDRCSDL NP_056 LLLHQLLLLFLSHLRRL 610 >>XP_011514530 (OMIM: 100740,112100) PREDICTED: acetylch (617 aa) initn: 3973 init1: 3973 opt: 3973 Z-score: 4295.7 bits: 805.0 E(85289): 0 Smith-Waterman score: 3973; 100.0% identity (100.0% similar) in 574 aa overlap (1-574:1-574) 10 20 30 40 50 60 pF1KB8 MRPPQCLLHTPSLASPLLLLLLWLLGGGVGAEGREDAELLVTVRGGRLRGIRLKTPGGPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MRPPQCLLHTPSLASPLLLLLLWLLGGGVGAEGREDAELLVTVRGGRLRGIRLKTPGGPV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 SAFLGIPFAEPPMGPRRFLPPEPKQPWSGVVDATTFQSVCYQYVDTLYPGFEGTEMWNPN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SAFLGIPFAEPPMGPRRFLPPEPKQPWSGVVDATTFQSVCYQYVDTLYPGFEGTEMWNPN 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 RELSEDCLYLNVWTPYPRPTSPTPVLVWIYGGGFYSGASSLDVYDGRFLVQAERTVLVSM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RELSEDCLYLNVWTPYPRPTSPTPVLVWIYGGGFYSGASSLDVYDGRFLVQAERTVLVSM 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 NYRVGAFGFLALPGSREAPGNVGLLDQRLALQWVQENVAAFGGDPTSVTLFGESAGAASV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NYRVGAFGFLALPGSREAPGNVGLLDQRLALQWVQENVAAFGGDPTSVTLFGESAGAASV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 GMHLLSPPSRGLFHRAVLQSGAPNGPWATVGMGEARRRATQLAHLVGCPPGGTGGNDTEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GMHLLSPPSRGLFHRAVLQSGAPNGPWATVGMGEARRRATQLAHLVGCPPGGTGGNDTEL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 VACLRTRPAQVLVNHEWHVLPQESVFRFSFVPVVDGDFLSDTPEALINAGDFHGLQVLVG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VACLRTRPAQVLVNHEWHVLPQESVFRFSFVPVVDGDFLSDTPEALINAGDFHGLQVLVG 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB8 VVKDEGSYFLVYGAPGFSKDNESLISRAEFLAGVRVGVPQVSDLAAEAVVLHYTDWLHPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VVKDEGSYFLVYGAPGFSKDNESLISRAEFLAGVRVGVPQVSDLAAEAVVLHYTDWLHPE 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB8 DPARLREALSDVVGDHNVVCPVAQLAGRLAAQGARVYAYVFEHRASTLSWPLWMGVPHGY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DPARLREALSDVVGDHNVVCPVAQLAGRLAAQGARVYAYVFEHRASTLSWPLWMGVPHGY 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB8 EIEFIFGIPLDPSRNYTAEEKIFAQRLMRYWANFARTGDPNEPRDPKAPQWPPYTAGAQQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EIEFIFGIPLDPSRNYTAEEKIFAQRLMRYWANFARTGDPNEPRDPKAPQWPPYTAGAQQ 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB8 YVSLDLRPLEVRRGLRAQACAFWNRFLPKLLSATDTLDEAERQWKAEFHRWSSYMVHWKN :::::::::::::::::::::::::::::::::: XP_011 YVSLDLRPLEVRRGLRAQACAFWNRFLPKLLSATASEAPSTCPGFTHGEAAPRPGLPLPL 550 560 570 580 590 600 610 pF1KB8 QFDHYSKQDRCSDL XP_011 LLLHQLLLLFLSHLRRL 610 >>NP_001289550 (OMIM: 100740,112100) acetylcholinesteras (617 aa) initn: 3973 init1: 3973 opt: 3973 Z-score: 4295.7 bits: 805.0 E(85289): 0 Smith-Waterman score: 3973; 100.0% identity (100.0% similar) in 574 aa overlap (1-574:1-574) 10 20 30 40 50 60 pF1KB8 MRPPQCLLHTPSLASPLLLLLLWLLGGGVGAEGREDAELLVTVRGGRLRGIRLKTPGGPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MRPPQCLLHTPSLASPLLLLLLWLLGGGVGAEGREDAELLVTVRGGRLRGIRLKTPGGPV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 SAFLGIPFAEPPMGPRRFLPPEPKQPWSGVVDATTFQSVCYQYVDTLYPGFEGTEMWNPN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SAFLGIPFAEPPMGPRRFLPPEPKQPWSGVVDATTFQSVCYQYVDTLYPGFEGTEMWNPN 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 RELSEDCLYLNVWTPYPRPTSPTPVLVWIYGGGFYSGASSLDVYDGRFLVQAERTVLVSM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RELSEDCLYLNVWTPYPRPTSPTPVLVWIYGGGFYSGASSLDVYDGRFLVQAERTVLVSM 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 NYRVGAFGFLALPGSREAPGNVGLLDQRLALQWVQENVAAFGGDPTSVTLFGESAGAASV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NYRVGAFGFLALPGSREAPGNVGLLDQRLALQWVQENVAAFGGDPTSVTLFGESAGAASV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 GMHLLSPPSRGLFHRAVLQSGAPNGPWATVGMGEARRRATQLAHLVGCPPGGTGGNDTEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GMHLLSPPSRGLFHRAVLQSGAPNGPWATVGMGEARRRATQLAHLVGCPPGGTGGNDTEL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 VACLRTRPAQVLVNHEWHVLPQESVFRFSFVPVVDGDFLSDTPEALINAGDFHGLQVLVG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VACLRTRPAQVLVNHEWHVLPQESVFRFSFVPVVDGDFLSDTPEALINAGDFHGLQVLVG 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB8 VVKDEGSYFLVYGAPGFSKDNESLISRAEFLAGVRVGVPQVSDLAAEAVVLHYTDWLHPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VVKDEGSYFLVYGAPGFSKDNESLISRAEFLAGVRVGVPQVSDLAAEAVVLHYTDWLHPE 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB8 DPARLREALSDVVGDHNVVCPVAQLAGRLAAQGARVYAYVFEHRASTLSWPLWMGVPHGY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DPARLREALSDVVGDHNVVCPVAQLAGRLAAQGARVYAYVFEHRASTLSWPLWMGVPHGY 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB8 EIEFIFGIPLDPSRNYTAEEKIFAQRLMRYWANFARTGDPNEPRDPKAPQWPPYTAGAQQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EIEFIFGIPLDPSRNYTAEEKIFAQRLMRYWANFARTGDPNEPRDPKAPQWPPYTAGAQQ 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB8 YVSLDLRPLEVRRGLRAQACAFWNRFLPKLLSATDTLDEAERQWKAEFHRWSSYMVHWKN :::::::::::::::::::::::::::::::::: NP_001 YVSLDLRPLEVRRGLRAQACAFWNRFLPKLLSATASEAPSTCPGFTHGEAAPRPGLPLPL 550 560 570 580 590 600 610 pF1KB8 QFDHYSKQDRCSDL NP_001 LLLHQLLLLFLSHLRRL 610 >>XP_011514527 (OMIM: 100740,112100) PREDICTED: acetylch (783 aa) initn: 3973 init1: 3973 opt: 3973 Z-score: 4294.3 bits: 805.0 E(85289): 0 Smith-Waterman score: 3973; 100.0% identity (100.0% similar) in 574 aa overlap (1-574:167-740) 10 20 30 pF1KB8 MRPPQCLLHTPSLASPLLLLLLWLLGGGVG :::::::::::::::::::::::::::::: XP_011 SALISSLLASRPTLHPFPFFLPADAACPAAMRPPQCLLHTPSLASPLLLLLLWLLGGGVG 140 150 160 170 180 190 40 50 60 70 80 90 pF1KB8 AEGREDAELLVTVRGGRLRGIRLKTPGGPVSAFLGIPFAEPPMGPRRFLPPEPKQPWSGV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AEGREDAELLVTVRGGRLRGIRLKTPGGPVSAFLGIPFAEPPMGPRRFLPPEPKQPWSGV 200 210 220 230 240 250 100 110 120 130 140 150 pF1KB8 VDATTFQSVCYQYVDTLYPGFEGTEMWNPNRELSEDCLYLNVWTPYPRPTSPTPVLVWIY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VDATTFQSVCYQYVDTLYPGFEGTEMWNPNRELSEDCLYLNVWTPYPRPTSPTPVLVWIY 260 270 280 290 300 310 160 170 180 190 200 210 pF1KB8 GGGFYSGASSLDVYDGRFLVQAERTVLVSMNYRVGAFGFLALPGSREAPGNVGLLDQRLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GGGFYSGASSLDVYDGRFLVQAERTVLVSMNYRVGAFGFLALPGSREAPGNVGLLDQRLA 320 330 340 350 360 370 220 230 240 250 260 270 pF1KB8 LQWVQENVAAFGGDPTSVTLFGESAGAASVGMHLLSPPSRGLFHRAVLQSGAPNGPWATV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LQWVQENVAAFGGDPTSVTLFGESAGAASVGMHLLSPPSRGLFHRAVLQSGAPNGPWATV 380 390 400 410 420 430 280 290 300 310 320 330 pF1KB8 GMGEARRRATQLAHLVGCPPGGTGGNDTELVACLRTRPAQVLVNHEWHVLPQESVFRFSF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GMGEARRRATQLAHLVGCPPGGTGGNDTELVACLRTRPAQVLVNHEWHVLPQESVFRFSF 440 450 460 470 480 490 340 350 360 370 380 390 pF1KB8 VPVVDGDFLSDTPEALINAGDFHGLQVLVGVVKDEGSYFLVYGAPGFSKDNESLISRAEF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VPVVDGDFLSDTPEALINAGDFHGLQVLVGVVKDEGSYFLVYGAPGFSKDNESLISRAEF 500 510 520 530 540 550 400 410 420 430 440 450 pF1KB8 LAGVRVGVPQVSDLAAEAVVLHYTDWLHPEDPARLREALSDVVGDHNVVCPVAQLAGRLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LAGVRVGVPQVSDLAAEAVVLHYTDWLHPEDPARLREALSDVVGDHNVVCPVAQLAGRLA 560 570 580 590 600 610 460 470 480 490 500 510 pF1KB8 AQGARVYAYVFEHRASTLSWPLWMGVPHGYEIEFIFGIPLDPSRNYTAEEKIFAQRLMRY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AQGARVYAYVFEHRASTLSWPLWMGVPHGYEIEFIFGIPLDPSRNYTAEEKIFAQRLMRY 620 630 640 650 660 670 520 530 540 550 560 570 pF1KB8 WANFARTGDPNEPRDPKAPQWPPYTAGAQQYVSLDLRPLEVRRGLRAQACAFWNRFLPKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 WANFARTGDPNEPRDPKAPQWPPYTAGAQQYVSLDLRPLEVRRGLRAQACAFWNRFLPKL 680 690 700 710 720 730 580 590 600 610 pF1KB8 LSATDTLDEAERQWKAEFHRWSSYMVHWKNQFDHYSKQDRCSDL :::: XP_011 LSATASEAPSTCPGFTHGEAAPRPGLPLPLLLLHQLLLLFLSHLRRL 740 750 760 770 780 >>NP_001269378 (OMIM: 100740,112100) acetylcholinesteras (526 aa) initn: 2476 init1: 2476 opt: 2487 Z-score: 2689.6 bits: 507.6 E(85289): 4.5e-143 Smith-Waterman score: 3507; 85.7% identity (85.7% similar) in 614 aa overlap (1-614:1-526) 10 20 30 40 50 60 pF1KB8 MRPPQCLLHTPSLASPLLLLLLWLLGGGVGAEGREDAELLVTVRGGRLRGIRLKTPGGPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MRPPQCLLHTPSLASPLLLLLLWLLGGGVGAEGREDAELLVTVRGGRLRGIRLKTPGGPV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 SAFLGIPFAEPPMGPRRFLPPEPKQPWSGVVDATTFQSVCYQYVDTLYPGFEGTEMWNPN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SAFLGIPFAEPPMGPRRFLPPEPKQPWSGVVDATTFQSVCYQYVDTLYPGFEGTEMWNPN 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 RELSEDCLYLNVWTPYPRPTSPTPVLVWIYGGGFYSGASSLDVYDGRFLVQAERTVLVSM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RELSEDCLYLNVWTPYPRPTSPTPVLVWIYGGGFYSGASSLDVYDGRFLVQAERTVLVSM 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 NYRVGAFGFLALPGSREAPGNVGLLDQRLALQWVQENVAAFGGDPTSVTLFGESAGAASV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NYRVGAFGFLALPGSREAPGNVGLLDQRLALQWVQENVAAFGGDPTSVTLFGESAGAASV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 GMHLLSPPSRGLFHRAVLQSGAPNGPWATVGMGEARRRATQLAHLVGCPPGGTGGNDTEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GMHLLSPPSRGLFHRAVLQSGAPNGPWATVGMGEARRRATQLAHLVGCPPGGTGGNDTEL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 VACLRTRPAQVLVNHEWHVLPQESVFRFSFVPVVDGDFLSDTPEALINAGDFHGLQVLVG :::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VACLRTRPAQVLVNHEWHVLPQESVFRFSFVPVVDGDFLSDTPEALINAGDFHGLQ---- 310 320 330 340 350 370 380 390 400 410 420 pF1KB8 VVKDEGSYFLVYGAPGFSKDNESLISRAEFLAGVRVGVPQVSDLAAEAVVLHYTDWLHPE NP_001 ------------------------------------------------------------ 430 440 450 460 470 480 pF1KB8 DPARLREALSDVVGDHNVVCPVAQLAGRLAAQGARVYAYVFEHRASTLSWPLWMGVPHGY :::::::::::::::::::::::::::::::::::: NP_001 ------------------------LAGRLAAQGARVYAYVFEHRASTLSWPLWMGVPHGY 360 370 380 390 490 500 510 520 530 540 pF1KB8 EIEFIFGIPLDPSRNYTAEEKIFAQRLMRYWANFARTGDPNEPRDPKAPQWPPYTAGAQQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EIEFIFGIPLDPSRNYTAEEKIFAQRLMRYWANFARTGDPNEPRDPKAPQWPPYTAGAQQ 400 410 420 430 440 450 550 560 570 580 590 600 pF1KB8 YVSLDLRPLEVRRGLRAQACAFWNRFLPKLLSATDTLDEAERQWKAEFHRWSSYMVHWKN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YVSLDLRPLEVRRGLRAQACAFWNRFLPKLLSATDTLDEAERQWKAEFHRWSSYMVHWKN 460 470 480 490 500 510 610 pF1KB8 QFDHYSKQDRCSDL :::::::::::::: NP_001 QFDHYSKQDRCSDL 520 614 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 12:24:30 2016 done: Fri Nov 4 12:24:31 2016 Total Scan time: 10.970 Total Display time: 0.130 Function used was FASTA [36.3.4 Apr, 2011]