FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB8384, 616 aa 1>>>pF1KB8384 616 - 616 aa - 616 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 10.2831+/-0.000423; mu= -1.4708+/- 0.026 mean_var=337.8319+/-71.735, 0's: 0 Z-trim(122.3): 42 B-trim: 1605 in 2/56 Lambda= 0.069779 statistics sampled from 40267 (40315) to 40267 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.772), E-opt: 0.2 (0.473), width: 16 Scan time: 11.440 The best scores are: opt bits E(85289) NP_000440 (OMIM: 209920,601863) DNA-binding protei ( 616) 4133 430.0 1.2e-119 XP_005245462 (OMIM: 209920,601863) PREDICTED: DNA- ( 616) 4133 430.0 1.2e-119 XP_005245463 (OMIM: 209920,601863) PREDICTED: DNA- ( 616) 4133 430.0 1.2e-119 NP_001020774 (OMIM: 209920,601863) DNA-binding pro ( 616) 4133 430.0 1.2e-119 XP_011508152 (OMIM: 209920,601863) PREDICTED: DNA- ( 616) 4133 430.0 1.2e-119 XP_011508151 (OMIM: 209920,601863) PREDICTED: DNA- ( 616) 4133 430.0 1.2e-119 XP_011508150 (OMIM: 209920,601863) PREDICTED: DNA- ( 616) 4133 430.0 1.2e-119 XP_011508149 (OMIM: 209920,601863) PREDICTED: DNA- ( 616) 4133 430.0 1.2e-119 XP_016857488 (OMIM: 209920,601863) PREDICTED: DNA- ( 445) 2976 313.4 1.1e-84 XP_016857489 (OMIM: 209920,601863) PREDICTED: DNA- ( 445) 2976 313.4 1.1e-84 NP_073752 (OMIM: 612660) DNA-binding protein RFX7 (1460) 806 95.4 1.4e-18 XP_005254660 (OMIM: 612660) PREDICTED: DNA-binding (1460) 806 95.4 1.4e-18 XP_016877995 (OMIM: 612660) PREDICTED: DNA-binding (1460) 806 95.4 1.4e-18 XP_016877997 (OMIM: 612660) PREDICTED: DNA-binding (1363) 613 76.0 9.6e-13 XP_016877996 (OMIM: 612660) PREDICTED: DNA-binding (1363) 613 76.0 9.6e-13 XP_011520227 (OMIM: 612660) PREDICTED: DNA-binding (1363) 613 76.0 9.6e-13 >>NP_000440 (OMIM: 209920,601863) DNA-binding protein RF (616 aa) initn: 4133 init1: 4133 opt: 4133 Z-score: 2269.3 bits: 430.0 E(85289): 1.2e-119 Smith-Waterman score: 4133; 100.0% identity (100.0% similar) in 616 aa overlap (1-616:1-616) 10 20 30 40 50 60 pF1KB8 MAEDEPDAKSPKTGGRAPPGGAEAGEPTTLLQRLRGTISKAVQNKVEGILQDVQKFSDND :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 MAEDEPDAKSPKTGGRAPPGGAEAGEPTTLLQRLRGTISKAVQNKVEGILQDVQKFSDND 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 KLYLYLQLPSGPTTGDKSSEPSTLSNEEYMYAYRWIRNHLEEHTDTCLPKQSVYDAYRKY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 KLYLYLQLPSGPTTGDKSSEPSTLSNEEYMYAYRWIRNHLEEHTDTCLPKQSVYDAYRKY 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 CESLACCRPLSTANFGKIIREIFPDIKARRLGGRGQSKYCYSGIRRKTLVSMPPLPGLDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 CESLACCRPLSTANFGKIIREIFPDIKARRLGGRGQSKYCYSGIRRKTLVSMPPLPGLDL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 KGSESPEMGPEVTPAPRDELVEAACALTCDWAERILKRSFSSIVEVARFLLQQHLISARS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 KGSESPEMGPEVTPAPRDELVEAACALTCDWAERILKRSFSSIVEVARFLLQQHLISARS 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 AHAHVLKAMGLAEEDEHAPRERSSKPKNGLENPEGGAHKKPERLAQPPKDLEARTGAGPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 AHAHVLKAMGLAEEDEHAPRERSSKPKNGLENPEGGAHKKPERLAQPPKDLEARTGAGPL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 ARGERKKSVVESSAPGANNLQVNALVARLPLLLPRAPRSLIPPIPVSPPILAPRLSSGAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 ARGERKKSVVESSAPGANNLQVNALVARLPLLLPRAPRSLIPPIPVSPPILAPRLSSGAL 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB8 KVATLPLSSRAGAPPAAVPIINMILPTVPALPGPGPGPGRAPPGGLTQPRGTENREVGIG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 KVATLPLSSRAGAPPAAVPIINMILPTVPALPGPGPGPGRAPPGGLTQPRGTENREVGIG 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB8 GDQGPHDKGVKRTAEVPVSEASGQAPPAKAAKQDIEDTASDAKRKRGRPRKKSGGSGERN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 GDQGPHDKGVKRTAEVPVSEASGQAPPAKAAKQDIEDTASDAKRKRGRPRKKSGGSGERN 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB8 STPLKSAAAMESAQSSRLPWETWGSGGEGNSAGGAERPGPMGEAEKGAVLAQGQGDGTVS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 STPLKSAAAMESAQSSRLPWETWGSGGEGNSAGGAERPGPMGEAEKGAVLAQGQGDGTVS 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB8 KGGRGPGSQHTKEAEDKIPLVPSKVSVIKGSRSQKEAFPLAKGEVDTAPQGNKDLKEHVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 KGGRGPGSQHTKEAEDKIPLVPSKVSVIKGSRSQKEAFPLAKGEVDTAPQGNKDLKEHVL 550 560 570 580 590 600 610 pF1KB8 QSSLSQEHKDPKATPP :::::::::::::::: NP_000 QSSLSQEHKDPKATPP 610 >>XP_005245462 (OMIM: 209920,601863) PREDICTED: DNA-bind (616 aa) initn: 4133 init1: 4133 opt: 4133 Z-score: 2269.3 bits: 430.0 E(85289): 1.2e-119 Smith-Waterman score: 4133; 100.0% identity (100.0% similar) in 616 aa overlap (1-616:1-616) 10 20 30 40 50 60 pF1KB8 MAEDEPDAKSPKTGGRAPPGGAEAGEPTTLLQRLRGTISKAVQNKVEGILQDVQKFSDND :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MAEDEPDAKSPKTGGRAPPGGAEAGEPTTLLQRLRGTISKAVQNKVEGILQDVQKFSDND 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 KLYLYLQLPSGPTTGDKSSEPSTLSNEEYMYAYRWIRNHLEEHTDTCLPKQSVYDAYRKY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 KLYLYLQLPSGPTTGDKSSEPSTLSNEEYMYAYRWIRNHLEEHTDTCLPKQSVYDAYRKY 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 CESLACCRPLSTANFGKIIREIFPDIKARRLGGRGQSKYCYSGIRRKTLVSMPPLPGLDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 CESLACCRPLSTANFGKIIREIFPDIKARRLGGRGQSKYCYSGIRRKTLVSMPPLPGLDL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 KGSESPEMGPEVTPAPRDELVEAACALTCDWAERILKRSFSSIVEVARFLLQQHLISARS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 KGSESPEMGPEVTPAPRDELVEAACALTCDWAERILKRSFSSIVEVARFLLQQHLISARS 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 AHAHVLKAMGLAEEDEHAPRERSSKPKNGLENPEGGAHKKPERLAQPPKDLEARTGAGPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 AHAHVLKAMGLAEEDEHAPRERSSKPKNGLENPEGGAHKKPERLAQPPKDLEARTGAGPL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 ARGERKKSVVESSAPGANNLQVNALVARLPLLLPRAPRSLIPPIPVSPPILAPRLSSGAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ARGERKKSVVESSAPGANNLQVNALVARLPLLLPRAPRSLIPPIPVSPPILAPRLSSGAL 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB8 KVATLPLSSRAGAPPAAVPIINMILPTVPALPGPGPGPGRAPPGGLTQPRGTENREVGIG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 KVATLPLSSRAGAPPAAVPIINMILPTVPALPGPGPGPGRAPPGGLTQPRGTENREVGIG 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB8 GDQGPHDKGVKRTAEVPVSEASGQAPPAKAAKQDIEDTASDAKRKRGRPRKKSGGSGERN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GDQGPHDKGVKRTAEVPVSEASGQAPPAKAAKQDIEDTASDAKRKRGRPRKKSGGSGERN 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB8 STPLKSAAAMESAQSSRLPWETWGSGGEGNSAGGAERPGPMGEAEKGAVLAQGQGDGTVS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 STPLKSAAAMESAQSSRLPWETWGSGGEGNSAGGAERPGPMGEAEKGAVLAQGQGDGTVS 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB8 KGGRGPGSQHTKEAEDKIPLVPSKVSVIKGSRSQKEAFPLAKGEVDTAPQGNKDLKEHVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 KGGRGPGSQHTKEAEDKIPLVPSKVSVIKGSRSQKEAFPLAKGEVDTAPQGNKDLKEHVL 550 560 570 580 590 600 610 pF1KB8 QSSLSQEHKDPKATPP :::::::::::::::: XP_005 QSSLSQEHKDPKATPP 610 >>XP_005245463 (OMIM: 209920,601863) PREDICTED: DNA-bind (616 aa) initn: 4133 init1: 4133 opt: 4133 Z-score: 2269.3 bits: 430.0 E(85289): 1.2e-119 Smith-Waterman score: 4133; 100.0% identity (100.0% similar) in 616 aa overlap (1-616:1-616) 10 20 30 40 50 60 pF1KB8 MAEDEPDAKSPKTGGRAPPGGAEAGEPTTLLQRLRGTISKAVQNKVEGILQDVQKFSDND :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MAEDEPDAKSPKTGGRAPPGGAEAGEPTTLLQRLRGTISKAVQNKVEGILQDVQKFSDND 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 KLYLYLQLPSGPTTGDKSSEPSTLSNEEYMYAYRWIRNHLEEHTDTCLPKQSVYDAYRKY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 KLYLYLQLPSGPTTGDKSSEPSTLSNEEYMYAYRWIRNHLEEHTDTCLPKQSVYDAYRKY 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 CESLACCRPLSTANFGKIIREIFPDIKARRLGGRGQSKYCYSGIRRKTLVSMPPLPGLDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 CESLACCRPLSTANFGKIIREIFPDIKARRLGGRGQSKYCYSGIRRKTLVSMPPLPGLDL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 KGSESPEMGPEVTPAPRDELVEAACALTCDWAERILKRSFSSIVEVARFLLQQHLISARS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 KGSESPEMGPEVTPAPRDELVEAACALTCDWAERILKRSFSSIVEVARFLLQQHLISARS 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 AHAHVLKAMGLAEEDEHAPRERSSKPKNGLENPEGGAHKKPERLAQPPKDLEARTGAGPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 AHAHVLKAMGLAEEDEHAPRERSSKPKNGLENPEGGAHKKPERLAQPPKDLEARTGAGPL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 ARGERKKSVVESSAPGANNLQVNALVARLPLLLPRAPRSLIPPIPVSPPILAPRLSSGAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ARGERKKSVVESSAPGANNLQVNALVARLPLLLPRAPRSLIPPIPVSPPILAPRLSSGAL 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB8 KVATLPLSSRAGAPPAAVPIINMILPTVPALPGPGPGPGRAPPGGLTQPRGTENREVGIG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 KVATLPLSSRAGAPPAAVPIINMILPTVPALPGPGPGPGRAPPGGLTQPRGTENREVGIG 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB8 GDQGPHDKGVKRTAEVPVSEASGQAPPAKAAKQDIEDTASDAKRKRGRPRKKSGGSGERN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GDQGPHDKGVKRTAEVPVSEASGQAPPAKAAKQDIEDTASDAKRKRGRPRKKSGGSGERN 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB8 STPLKSAAAMESAQSSRLPWETWGSGGEGNSAGGAERPGPMGEAEKGAVLAQGQGDGTVS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 STPLKSAAAMESAQSSRLPWETWGSGGEGNSAGGAERPGPMGEAEKGAVLAQGQGDGTVS 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB8 KGGRGPGSQHTKEAEDKIPLVPSKVSVIKGSRSQKEAFPLAKGEVDTAPQGNKDLKEHVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 KGGRGPGSQHTKEAEDKIPLVPSKVSVIKGSRSQKEAFPLAKGEVDTAPQGNKDLKEHVL 550 560 570 580 590 600 610 pF1KB8 QSSLSQEHKDPKATPP :::::::::::::::: XP_005 QSSLSQEHKDPKATPP 610 >>NP_001020774 (OMIM: 209920,601863) DNA-binding protein (616 aa) initn: 4133 init1: 4133 opt: 4133 Z-score: 2269.3 bits: 430.0 E(85289): 1.2e-119 Smith-Waterman score: 4133; 100.0% identity (100.0% similar) in 616 aa overlap (1-616:1-616) 10 20 30 40 50 60 pF1KB8 MAEDEPDAKSPKTGGRAPPGGAEAGEPTTLLQRLRGTISKAVQNKVEGILQDVQKFSDND :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MAEDEPDAKSPKTGGRAPPGGAEAGEPTTLLQRLRGTISKAVQNKVEGILQDVQKFSDND 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 KLYLYLQLPSGPTTGDKSSEPSTLSNEEYMYAYRWIRNHLEEHTDTCLPKQSVYDAYRKY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KLYLYLQLPSGPTTGDKSSEPSTLSNEEYMYAYRWIRNHLEEHTDTCLPKQSVYDAYRKY 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 CESLACCRPLSTANFGKIIREIFPDIKARRLGGRGQSKYCYSGIRRKTLVSMPPLPGLDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 CESLACCRPLSTANFGKIIREIFPDIKARRLGGRGQSKYCYSGIRRKTLVSMPPLPGLDL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 KGSESPEMGPEVTPAPRDELVEAACALTCDWAERILKRSFSSIVEVARFLLQQHLISARS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KGSESPEMGPEVTPAPRDELVEAACALTCDWAERILKRSFSSIVEVARFLLQQHLISARS 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 AHAHVLKAMGLAEEDEHAPRERSSKPKNGLENPEGGAHKKPERLAQPPKDLEARTGAGPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AHAHVLKAMGLAEEDEHAPRERSSKPKNGLENPEGGAHKKPERLAQPPKDLEARTGAGPL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 ARGERKKSVVESSAPGANNLQVNALVARLPLLLPRAPRSLIPPIPVSPPILAPRLSSGAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ARGERKKSVVESSAPGANNLQVNALVARLPLLLPRAPRSLIPPIPVSPPILAPRLSSGAL 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB8 KVATLPLSSRAGAPPAAVPIINMILPTVPALPGPGPGPGRAPPGGLTQPRGTENREVGIG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KVATLPLSSRAGAPPAAVPIINMILPTVPALPGPGPGPGRAPPGGLTQPRGTENREVGIG 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB8 GDQGPHDKGVKRTAEVPVSEASGQAPPAKAAKQDIEDTASDAKRKRGRPRKKSGGSGERN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GDQGPHDKGVKRTAEVPVSEASGQAPPAKAAKQDIEDTASDAKRKRGRPRKKSGGSGERN 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB8 STPLKSAAAMESAQSSRLPWETWGSGGEGNSAGGAERPGPMGEAEKGAVLAQGQGDGTVS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 STPLKSAAAMESAQSSRLPWETWGSGGEGNSAGGAERPGPMGEAEKGAVLAQGQGDGTVS 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB8 KGGRGPGSQHTKEAEDKIPLVPSKVSVIKGSRSQKEAFPLAKGEVDTAPQGNKDLKEHVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KGGRGPGSQHTKEAEDKIPLVPSKVSVIKGSRSQKEAFPLAKGEVDTAPQGNKDLKEHVL 550 560 570 580 590 600 610 pF1KB8 QSSLSQEHKDPKATPP :::::::::::::::: NP_001 QSSLSQEHKDPKATPP 610 >>XP_011508152 (OMIM: 209920,601863) PREDICTED: DNA-bind (616 aa) initn: 4133 init1: 4133 opt: 4133 Z-score: 2269.3 bits: 430.0 E(85289): 1.2e-119 Smith-Waterman score: 4133; 100.0% identity (100.0% similar) in 616 aa overlap (1-616:1-616) 10 20 30 40 50 60 pF1KB8 MAEDEPDAKSPKTGGRAPPGGAEAGEPTTLLQRLRGTISKAVQNKVEGILQDVQKFSDND :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MAEDEPDAKSPKTGGRAPPGGAEAGEPTTLLQRLRGTISKAVQNKVEGILQDVQKFSDND 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 KLYLYLQLPSGPTTGDKSSEPSTLSNEEYMYAYRWIRNHLEEHTDTCLPKQSVYDAYRKY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KLYLYLQLPSGPTTGDKSSEPSTLSNEEYMYAYRWIRNHLEEHTDTCLPKQSVYDAYRKY 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 CESLACCRPLSTANFGKIIREIFPDIKARRLGGRGQSKYCYSGIRRKTLVSMPPLPGLDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 CESLACCRPLSTANFGKIIREIFPDIKARRLGGRGQSKYCYSGIRRKTLVSMPPLPGLDL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 KGSESPEMGPEVTPAPRDELVEAACALTCDWAERILKRSFSSIVEVARFLLQQHLISARS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KGSESPEMGPEVTPAPRDELVEAACALTCDWAERILKRSFSSIVEVARFLLQQHLISARS 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 AHAHVLKAMGLAEEDEHAPRERSSKPKNGLENPEGGAHKKPERLAQPPKDLEARTGAGPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AHAHVLKAMGLAEEDEHAPRERSSKPKNGLENPEGGAHKKPERLAQPPKDLEARTGAGPL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 ARGERKKSVVESSAPGANNLQVNALVARLPLLLPRAPRSLIPPIPVSPPILAPRLSSGAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ARGERKKSVVESSAPGANNLQVNALVARLPLLLPRAPRSLIPPIPVSPPILAPRLSSGAL 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB8 KVATLPLSSRAGAPPAAVPIINMILPTVPALPGPGPGPGRAPPGGLTQPRGTENREVGIG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KVATLPLSSRAGAPPAAVPIINMILPTVPALPGPGPGPGRAPPGGLTQPRGTENREVGIG 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB8 GDQGPHDKGVKRTAEVPVSEASGQAPPAKAAKQDIEDTASDAKRKRGRPRKKSGGSGERN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GDQGPHDKGVKRTAEVPVSEASGQAPPAKAAKQDIEDTASDAKRKRGRPRKKSGGSGERN 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB8 STPLKSAAAMESAQSSRLPWETWGSGGEGNSAGGAERPGPMGEAEKGAVLAQGQGDGTVS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 STPLKSAAAMESAQSSRLPWETWGSGGEGNSAGGAERPGPMGEAEKGAVLAQGQGDGTVS 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB8 KGGRGPGSQHTKEAEDKIPLVPSKVSVIKGSRSQKEAFPLAKGEVDTAPQGNKDLKEHVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KGGRGPGSQHTKEAEDKIPLVPSKVSVIKGSRSQKEAFPLAKGEVDTAPQGNKDLKEHVL 550 560 570 580 590 600 610 pF1KB8 QSSLSQEHKDPKATPP :::::::::::::::: XP_011 QSSLSQEHKDPKATPP 610 >>XP_011508151 (OMIM: 209920,601863) PREDICTED: DNA-bind (616 aa) initn: 4133 init1: 4133 opt: 4133 Z-score: 2269.3 bits: 430.0 E(85289): 1.2e-119 Smith-Waterman score: 4133; 100.0% identity (100.0% similar) in 616 aa overlap (1-616:1-616) 10 20 30 40 50 60 pF1KB8 MAEDEPDAKSPKTGGRAPPGGAEAGEPTTLLQRLRGTISKAVQNKVEGILQDVQKFSDND :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MAEDEPDAKSPKTGGRAPPGGAEAGEPTTLLQRLRGTISKAVQNKVEGILQDVQKFSDND 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 KLYLYLQLPSGPTTGDKSSEPSTLSNEEYMYAYRWIRNHLEEHTDTCLPKQSVYDAYRKY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KLYLYLQLPSGPTTGDKSSEPSTLSNEEYMYAYRWIRNHLEEHTDTCLPKQSVYDAYRKY 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 CESLACCRPLSTANFGKIIREIFPDIKARRLGGRGQSKYCYSGIRRKTLVSMPPLPGLDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 CESLACCRPLSTANFGKIIREIFPDIKARRLGGRGQSKYCYSGIRRKTLVSMPPLPGLDL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 KGSESPEMGPEVTPAPRDELVEAACALTCDWAERILKRSFSSIVEVARFLLQQHLISARS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KGSESPEMGPEVTPAPRDELVEAACALTCDWAERILKRSFSSIVEVARFLLQQHLISARS 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 AHAHVLKAMGLAEEDEHAPRERSSKPKNGLENPEGGAHKKPERLAQPPKDLEARTGAGPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AHAHVLKAMGLAEEDEHAPRERSSKPKNGLENPEGGAHKKPERLAQPPKDLEARTGAGPL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 ARGERKKSVVESSAPGANNLQVNALVARLPLLLPRAPRSLIPPIPVSPPILAPRLSSGAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ARGERKKSVVESSAPGANNLQVNALVARLPLLLPRAPRSLIPPIPVSPPILAPRLSSGAL 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB8 KVATLPLSSRAGAPPAAVPIINMILPTVPALPGPGPGPGRAPPGGLTQPRGTENREVGIG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KVATLPLSSRAGAPPAAVPIINMILPTVPALPGPGPGPGRAPPGGLTQPRGTENREVGIG 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB8 GDQGPHDKGVKRTAEVPVSEASGQAPPAKAAKQDIEDTASDAKRKRGRPRKKSGGSGERN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GDQGPHDKGVKRTAEVPVSEASGQAPPAKAAKQDIEDTASDAKRKRGRPRKKSGGSGERN 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB8 STPLKSAAAMESAQSSRLPWETWGSGGEGNSAGGAERPGPMGEAEKGAVLAQGQGDGTVS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 STPLKSAAAMESAQSSRLPWETWGSGGEGNSAGGAERPGPMGEAEKGAVLAQGQGDGTVS 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB8 KGGRGPGSQHTKEAEDKIPLVPSKVSVIKGSRSQKEAFPLAKGEVDTAPQGNKDLKEHVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KGGRGPGSQHTKEAEDKIPLVPSKVSVIKGSRSQKEAFPLAKGEVDTAPQGNKDLKEHVL 550 560 570 580 590 600 610 pF1KB8 QSSLSQEHKDPKATPP :::::::::::::::: XP_011 QSSLSQEHKDPKATPP 610 >>XP_011508150 (OMIM: 209920,601863) PREDICTED: DNA-bind (616 aa) initn: 4133 init1: 4133 opt: 4133 Z-score: 2269.3 bits: 430.0 E(85289): 1.2e-119 Smith-Waterman score: 4133; 100.0% identity (100.0% similar) in 616 aa overlap (1-616:1-616) 10 20 30 40 50 60 pF1KB8 MAEDEPDAKSPKTGGRAPPGGAEAGEPTTLLQRLRGTISKAVQNKVEGILQDVQKFSDND :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MAEDEPDAKSPKTGGRAPPGGAEAGEPTTLLQRLRGTISKAVQNKVEGILQDVQKFSDND 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 KLYLYLQLPSGPTTGDKSSEPSTLSNEEYMYAYRWIRNHLEEHTDTCLPKQSVYDAYRKY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KLYLYLQLPSGPTTGDKSSEPSTLSNEEYMYAYRWIRNHLEEHTDTCLPKQSVYDAYRKY 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 CESLACCRPLSTANFGKIIREIFPDIKARRLGGRGQSKYCYSGIRRKTLVSMPPLPGLDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 CESLACCRPLSTANFGKIIREIFPDIKARRLGGRGQSKYCYSGIRRKTLVSMPPLPGLDL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 KGSESPEMGPEVTPAPRDELVEAACALTCDWAERILKRSFSSIVEVARFLLQQHLISARS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KGSESPEMGPEVTPAPRDELVEAACALTCDWAERILKRSFSSIVEVARFLLQQHLISARS 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 AHAHVLKAMGLAEEDEHAPRERSSKPKNGLENPEGGAHKKPERLAQPPKDLEARTGAGPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AHAHVLKAMGLAEEDEHAPRERSSKPKNGLENPEGGAHKKPERLAQPPKDLEARTGAGPL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 ARGERKKSVVESSAPGANNLQVNALVARLPLLLPRAPRSLIPPIPVSPPILAPRLSSGAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ARGERKKSVVESSAPGANNLQVNALVARLPLLLPRAPRSLIPPIPVSPPILAPRLSSGAL 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB8 KVATLPLSSRAGAPPAAVPIINMILPTVPALPGPGPGPGRAPPGGLTQPRGTENREVGIG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KVATLPLSSRAGAPPAAVPIINMILPTVPALPGPGPGPGRAPPGGLTQPRGTENREVGIG 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB8 GDQGPHDKGVKRTAEVPVSEASGQAPPAKAAKQDIEDTASDAKRKRGRPRKKSGGSGERN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GDQGPHDKGVKRTAEVPVSEASGQAPPAKAAKQDIEDTASDAKRKRGRPRKKSGGSGERN 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB8 STPLKSAAAMESAQSSRLPWETWGSGGEGNSAGGAERPGPMGEAEKGAVLAQGQGDGTVS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 STPLKSAAAMESAQSSRLPWETWGSGGEGNSAGGAERPGPMGEAEKGAVLAQGQGDGTVS 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB8 KGGRGPGSQHTKEAEDKIPLVPSKVSVIKGSRSQKEAFPLAKGEVDTAPQGNKDLKEHVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KGGRGPGSQHTKEAEDKIPLVPSKVSVIKGSRSQKEAFPLAKGEVDTAPQGNKDLKEHVL 550 560 570 580 590 600 610 pF1KB8 QSSLSQEHKDPKATPP :::::::::::::::: XP_011 QSSLSQEHKDPKATPP 610 >>XP_011508149 (OMIM: 209920,601863) PREDICTED: DNA-bind (616 aa) initn: 4133 init1: 4133 opt: 4133 Z-score: 2269.3 bits: 430.0 E(85289): 1.2e-119 Smith-Waterman score: 4133; 100.0% identity (100.0% similar) in 616 aa overlap (1-616:1-616) 10 20 30 40 50 60 pF1KB8 MAEDEPDAKSPKTGGRAPPGGAEAGEPTTLLQRLRGTISKAVQNKVEGILQDVQKFSDND :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MAEDEPDAKSPKTGGRAPPGGAEAGEPTTLLQRLRGTISKAVQNKVEGILQDVQKFSDND 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 KLYLYLQLPSGPTTGDKSSEPSTLSNEEYMYAYRWIRNHLEEHTDTCLPKQSVYDAYRKY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KLYLYLQLPSGPTTGDKSSEPSTLSNEEYMYAYRWIRNHLEEHTDTCLPKQSVYDAYRKY 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 CESLACCRPLSTANFGKIIREIFPDIKARRLGGRGQSKYCYSGIRRKTLVSMPPLPGLDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 CESLACCRPLSTANFGKIIREIFPDIKARRLGGRGQSKYCYSGIRRKTLVSMPPLPGLDL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 KGSESPEMGPEVTPAPRDELVEAACALTCDWAERILKRSFSSIVEVARFLLQQHLISARS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KGSESPEMGPEVTPAPRDELVEAACALTCDWAERILKRSFSSIVEVARFLLQQHLISARS 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 AHAHVLKAMGLAEEDEHAPRERSSKPKNGLENPEGGAHKKPERLAQPPKDLEARTGAGPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AHAHVLKAMGLAEEDEHAPRERSSKPKNGLENPEGGAHKKPERLAQPPKDLEARTGAGPL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 ARGERKKSVVESSAPGANNLQVNALVARLPLLLPRAPRSLIPPIPVSPPILAPRLSSGAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ARGERKKSVVESSAPGANNLQVNALVARLPLLLPRAPRSLIPPIPVSPPILAPRLSSGAL 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB8 KVATLPLSSRAGAPPAAVPIINMILPTVPALPGPGPGPGRAPPGGLTQPRGTENREVGIG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KVATLPLSSRAGAPPAAVPIINMILPTVPALPGPGPGPGRAPPGGLTQPRGTENREVGIG 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB8 GDQGPHDKGVKRTAEVPVSEASGQAPPAKAAKQDIEDTASDAKRKRGRPRKKSGGSGERN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GDQGPHDKGVKRTAEVPVSEASGQAPPAKAAKQDIEDTASDAKRKRGRPRKKSGGSGERN 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB8 STPLKSAAAMESAQSSRLPWETWGSGGEGNSAGGAERPGPMGEAEKGAVLAQGQGDGTVS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 STPLKSAAAMESAQSSRLPWETWGSGGEGNSAGGAERPGPMGEAEKGAVLAQGQGDGTVS 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB8 KGGRGPGSQHTKEAEDKIPLVPSKVSVIKGSRSQKEAFPLAKGEVDTAPQGNKDLKEHVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KGGRGPGSQHTKEAEDKIPLVPSKVSVIKGSRSQKEAFPLAKGEVDTAPQGNKDLKEHVL 550 560 570 580 590 600 610 pF1KB8 QSSLSQEHKDPKATPP :::::::::::::::: XP_011 QSSLSQEHKDPKATPP 610 >>XP_016857488 (OMIM: 209920,601863) PREDICTED: DNA-bind (445 aa) initn: 2976 init1: 2976 opt: 2976 Z-score: 1641.7 bits: 313.4 E(85289): 1.1e-84 Smith-Waterman score: 2976; 100.0% identity (100.0% similar) in 445 aa overlap (172-616:1-445) 150 160 170 180 190 200 pF1KB8 IFPDIKARRLGGRGQSKYCYSGIRRKTLVSMPPLPGLDLKGSESPEMGPEVTPAPRDELV :::::::::::::::::::::::::::::: XP_016 MPPLPGLDLKGSESPEMGPEVTPAPRDELV 10 20 30 210 220 230 240 250 260 pF1KB8 EAACALTCDWAERILKRSFSSIVEVARFLLQQHLISARSAHAHVLKAMGLAEEDEHAPRE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EAACALTCDWAERILKRSFSSIVEVARFLLQQHLISARSAHAHVLKAMGLAEEDEHAPRE 40 50 60 70 80 90 270 280 290 300 310 320 pF1KB8 RSSKPKNGLENPEGGAHKKPERLAQPPKDLEARTGAGPLARGERKKSVVESSAPGANNLQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RSSKPKNGLENPEGGAHKKPERLAQPPKDLEARTGAGPLARGERKKSVVESSAPGANNLQ 100 110 120 130 140 150 330 340 350 360 370 380 pF1KB8 VNALVARLPLLLPRAPRSLIPPIPVSPPILAPRLSSGALKVATLPLSSRAGAPPAAVPII :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VNALVARLPLLLPRAPRSLIPPIPVSPPILAPRLSSGALKVATLPLSSRAGAPPAAVPII 160 170 180 190 200 210 390 400 410 420 430 440 pF1KB8 NMILPTVPALPGPGPGPGRAPPGGLTQPRGTENREVGIGGDQGPHDKGVKRTAEVPVSEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NMILPTVPALPGPGPGPGRAPPGGLTQPRGTENREVGIGGDQGPHDKGVKRTAEVPVSEA 220 230 240 250 260 270 450 460 470 480 490 500 pF1KB8 SGQAPPAKAAKQDIEDTASDAKRKRGRPRKKSGGSGERNSTPLKSAAAMESAQSSRLPWE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SGQAPPAKAAKQDIEDTASDAKRKRGRPRKKSGGSGERNSTPLKSAAAMESAQSSRLPWE 280 290 300 310 320 330 510 520 530 540 550 560 pF1KB8 TWGSGGEGNSAGGAERPGPMGEAEKGAVLAQGQGDGTVSKGGRGPGSQHTKEAEDKIPLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TWGSGGEGNSAGGAERPGPMGEAEKGAVLAQGQGDGTVSKGGRGPGSQHTKEAEDKIPLV 340 350 360 370 380 390 570 580 590 600 610 pF1KB8 PSKVSVIKGSRSQKEAFPLAKGEVDTAPQGNKDLKEHVLQSSLSQEHKDPKATPP ::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PSKVSVIKGSRSQKEAFPLAKGEVDTAPQGNKDLKEHVLQSSLSQEHKDPKATPP 400 410 420 430 440 >>XP_016857489 (OMIM: 209920,601863) PREDICTED: DNA-bind (445 aa) initn: 2976 init1: 2976 opt: 2976 Z-score: 1641.7 bits: 313.4 E(85289): 1.1e-84 Smith-Waterman score: 2976; 100.0% identity (100.0% similar) in 445 aa overlap (172-616:1-445) 150 160 170 180 190 200 pF1KB8 IFPDIKARRLGGRGQSKYCYSGIRRKTLVSMPPLPGLDLKGSESPEMGPEVTPAPRDELV :::::::::::::::::::::::::::::: XP_016 MPPLPGLDLKGSESPEMGPEVTPAPRDELV 10 20 30 210 220 230 240 250 260 pF1KB8 EAACALTCDWAERILKRSFSSIVEVARFLLQQHLISARSAHAHVLKAMGLAEEDEHAPRE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EAACALTCDWAERILKRSFSSIVEVARFLLQQHLISARSAHAHVLKAMGLAEEDEHAPRE 40 50 60 70 80 90 270 280 290 300 310 320 pF1KB8 RSSKPKNGLENPEGGAHKKPERLAQPPKDLEARTGAGPLARGERKKSVVESSAPGANNLQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RSSKPKNGLENPEGGAHKKPERLAQPPKDLEARTGAGPLARGERKKSVVESSAPGANNLQ 100 110 120 130 140 150 330 340 350 360 370 380 pF1KB8 VNALVARLPLLLPRAPRSLIPPIPVSPPILAPRLSSGALKVATLPLSSRAGAPPAAVPII :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VNALVARLPLLLPRAPRSLIPPIPVSPPILAPRLSSGALKVATLPLSSRAGAPPAAVPII 160 170 180 190 200 210 390 400 410 420 430 440 pF1KB8 NMILPTVPALPGPGPGPGRAPPGGLTQPRGTENREVGIGGDQGPHDKGVKRTAEVPVSEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NMILPTVPALPGPGPGPGRAPPGGLTQPRGTENREVGIGGDQGPHDKGVKRTAEVPVSEA 220 230 240 250 260 270 450 460 470 480 490 500 pF1KB8 SGQAPPAKAAKQDIEDTASDAKRKRGRPRKKSGGSGERNSTPLKSAAAMESAQSSRLPWE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SGQAPPAKAAKQDIEDTASDAKRKRGRPRKKSGGSGERNSTPLKSAAAMESAQSSRLPWE 280 290 300 310 320 330 510 520 530 540 550 560 pF1KB8 TWGSGGEGNSAGGAERPGPMGEAEKGAVLAQGQGDGTVSKGGRGPGSQHTKEAEDKIPLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TWGSGGEGNSAGGAERPGPMGEAEKGAVLAQGQGDGTVSKGGRGPGSQHTKEAEDKIPLV 340 350 360 370 380 390 570 580 590 600 610 pF1KB8 PSKVSVIKGSRSQKEAFPLAKGEVDTAPQGNKDLKEHVLQSSLSQEHKDPKATPP ::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PSKVSVIKGSRSQKEAFPLAKGEVDTAPQGNKDLKEHVLQSSLSQEHKDPKATPP 400 410 420 430 440 616 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 12:26:34 2016 done: Fri Nov 4 12:26:36 2016 Total Scan time: 11.440 Total Display time: 0.100 Function used was FASTA [36.3.4 Apr, 2011]