FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB8385, 423 aa 1>>>pF1KB8385 423 - 423 aa - 423 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 7.6559+/-0.000934; mu= 10.8992+/- 0.057 mean_var=246.3734+/-50.231, 0's: 0 Z-trim(114.7): 118 B-trim: 118 in 1/51 Lambda= 0.081710 statistics sampled from 15116 (15237) to 15116 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.777), E-opt: 0.2 (0.468), width: 16 Scan time: 3.440 The best scores are: opt bits E(32554) CCDS4068.1 NR2F1 gene_id:7025|Hs108|chr5 ( 423) 2937 358.9 5.5e-99 CCDS10375.1 NR2F2 gene_id:7026|Hs108|chr15 ( 414) 2459 302.5 5e-82 CCDS45358.1 NR2F2 gene_id:7026|Hs108|chr15 ( 281) 1713 214.3 1.2e-55 CCDS45359.1 NR2F2 gene_id:7026|Hs108|chr15 ( 261) 1672 209.5 3.1e-54 CCDS12352.1 NR2F6 gene_id:2063|Hs108|chr19 ( 404) 1243 159.1 6.9e-39 CCDS1248.1 RXRG gene_id:6258|Hs108|chr1 ( 463) 976 127.7 2.2e-29 CCDS4768.1 RXRB gene_id:6257|Hs108|chr6 ( 533) 976 127.8 2.5e-29 CCDS35172.1 RXRA gene_id:6256|Hs108|chr9 ( 462) 972 127.3 3.1e-29 CCDS59007.1 RXRB gene_id:6257|Hs108|chr6 ( 537) 973 127.5 3.2e-29 CCDS72970.1 RXRG gene_id:6258|Hs108|chr1 ( 340) 953 124.9 1.2e-28 CCDS74728.1 HNF4A gene_id:3172|Hs108|chr20 ( 449) 796 106.5 5.4e-23 CCDS46605.1 HNF4A gene_id:3172|Hs108|chr20 ( 464) 786 105.3 1.2e-22 CCDS13330.1 HNF4A gene_id:3172|Hs108|chr20 ( 474) 786 105.4 1.3e-22 CCDS46604.1 HNF4A gene_id:3172|Hs108|chr20 ( 442) 785 105.2 1.3e-22 CCDS42876.1 HNF4A gene_id:3172|Hs108|chr20 ( 452) 785 105.2 1.3e-22 CCDS13331.1 HNF4A gene_id:3172|Hs108|chr20 ( 417) 774 103.9 3.1e-22 CCDS68131.1 HNF4A gene_id:3172|Hs108|chr20 ( 395) 773 103.7 3.3e-22 CCDS83303.1 HNF4G gene_id:3174|Hs108|chr8 ( 408) 764 102.7 6.9e-22 CCDS6220.2 HNF4G gene_id:3174|Hs108|chr8 ( 445) 764 102.7 7.3e-22 CCDS9850.2 ESRRB gene_id:2103|Hs108|chr14 ( 508) 675 92.3 1.1e-18 CCDS1517.1 ESRRG gene_id:2104|Hs108|chr1 ( 435) 672 91.9 1.3e-18 CCDS41468.1 ESRRG gene_id:2104|Hs108|chr1 ( 458) 672 91.9 1.4e-18 CCDS8818.1 NR4A1 gene_id:3164|Hs108|chr12 ( 598) 644 88.7 1.6e-17 CCDS55828.1 NR4A1 gene_id:3164|Hs108|chr12 ( 611) 644 88.7 1.6e-17 CCDS73471.1 NR4A1 gene_id:3164|Hs108|chr12 ( 652) 644 88.8 1.7e-17 CCDS8850.1 RARG gene_id:5916|Hs108|chr12 ( 454) 599 83.3 5.3e-16 CCDS73750.1 NR2E3 gene_id:10002|Hs108|chr15 ( 410) 596 82.9 6.4e-16 CCDS41790.1 RARG gene_id:5916|Hs108|chr12 ( 443) 594 82.7 7.9e-16 CCDS58236.1 RARG gene_id:5916|Hs108|chr12 ( 382) 583 81.3 1.8e-15 CCDS11366.1 RARA gene_id:5914|Hs108|chr17 ( 462) 572 80.1 4.9e-15 CCDS2642.1 RARB gene_id:5915|Hs108|chr3 ( 448) 567 79.5 7.2e-15 CCDS42317.1 RARA gene_id:5914|Hs108|chr17 ( 457) 567 79.5 7.3e-15 CCDS5063.1 NR2E1 gene_id:7101|Hs108|chr6 ( 385) 552 77.7 2.2e-14 CCDS69165.1 NR2E1 gene_id:7101|Hs108|chr6 ( 422) 552 77.7 2.4e-14 CCDS2201.1 NR4A2 gene_id:4929|Hs108|chr2 ( 598) 527 74.9 2.3e-13 CCDS58237.1 RARG gene_id:5916|Hs108|chr12 ( 432) 468 67.8 2.3e-11 CCDS6743.1 NR4A3 gene_id:8013|Hs108|chr9 ( 626) 457 66.7 7.1e-11 CCDS6742.1 NR4A3 gene_id:8013|Hs108|chr9 ( 637) 457 66.7 7.2e-11 >>CCDS4068.1 NR2F1 gene_id:7025|Hs108|chr5 (423 aa) initn: 2937 init1: 2937 opt: 2937 Z-score: 1890.6 bits: 358.9 E(32554): 5.5e-99 Smith-Waterman score: 2937; 100.0% identity (100.0% similar) in 423 aa overlap (1-423:1-423) 10 20 30 40 50 60 pF1KB8 MAMVVSSWRDPQDDVAGGNPGGPNPAAQAARGGGGGAGEQQQQAGSGAPHTPQTPGQPGA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS40 MAMVVSSWRDPQDDVAGGNPGGPNPAAQAARGGGGGAGEQQQQAGSGAPHTPQTPGQPGA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 PATPGTAGDKGQGPPGSGQSQQHIECVVCGDKSSGKHYGQFTCEGCKSFFKRSVRRNLTY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS40 PATPGTAGDKGQGPPGSGQSQQHIECVVCGDKSSGKHYGQFTCEGCKSFFKRSVRRNLTY 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 TCRANRNCPIDQHHRNQCQYCRLKKCLKVGMRREAVQRGRMPPTQPNPGQYALTNGDPLN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS40 TCRANRNCPIDQHHRNQCQYCRLKKCLKVGMRREAVQRGRMPPTQPNPGQYALTNGDPLN 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 GHCYLSGYISLLLRAEPYPTSRYGSQCMQPNNIMGIENICELAARLLFSAVEWARNIPFF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS40 GHCYLSGYISLLLRAEPYPTSRYGSQCMQPNNIMGIENICELAARLLFSAVEWARNIPFF 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 PDLQITDQVSLLRLTWSELFVLNAAQCSMPLHVAPLLAAAGLHASPMSADRVVAFMDHIR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS40 PDLQITDQVSLLRLTWSELFVLNAAQCSMPLHVAPLLAAAGLHASPMSADRVVAFMDHIR 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 IFQEQVEKLKALHVDSAEYSCLKAIVLFTSDACGLSDAAHIESLQEKSQCALEEYVRSQY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS40 IFQEQVEKLKALHVDSAEYSCLKAIVLFTSDACGLSDAAHIESLQEKSQCALEEYVRSQY 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB8 PNQPSRFGKLLLRLPSLRTVSSSVIEQLFFVRLVGKTPIETLIRDMLLSGSSFNWPYMSI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS40 PNQPSRFGKLLLRLPSLRTVSSSVIEQLFFVRLVGKTPIETLIRDMLLSGSSFNWPYMSI 370 380 390 400 410 420 pF1KB8 QCS ::: CCDS40 QCS >>CCDS10375.1 NR2F2 gene_id:7026|Hs108|chr15 (414 aa) initn: 2271 init1: 2271 opt: 2459 Z-score: 1586.2 bits: 302.5 E(32554): 5e-82 Smith-Waterman score: 2459; 85.9% identity (90.8% similar) in 426 aa overlap (1-421:1-414) 10 20 30 40 50 60 pF1KB8 MAMVVSSWRDPQDDVAGGNPGGPNPAAQAARGGGGGAGEQQQQAGSGAPHTPQTPGQPGA ::::::.::::::.: ::. . :. : : ::::::::::: : CCDS10 MAMVVSTWRDPQDEV----PGSQGSQASQAPPVPGPP--------PGAPHTPQTPGQGGP 10 20 30 40 70 80 90 100 110 pF1KB8 PATPGTAGDKGQGPPGSG-----QSQQHIECVVCGDKSSGKHYGQFTCEGCKSFFKRSVR .::. .. ::: ::. :.::::::::::::::::::::::::::::::::::: CCDS10 ASTPAQTAAGGQGGPGGPGSDKQQQQQHIECVVCGDKSSGKHYGQFTCEGCKSFFKRSVR 50 60 70 80 90 100 120 130 140 150 160 170 pF1KB8 RNLTYTCRANRNCPIDQHHRNQCQYCRLKKCLKVGMRREAVQRGRMPPTQPNPGQYALTN :::.:::::::::::::::::::::::::::::::::::::::::::::::. ::.:::: CCDS10 RNLSYTCRANRNCPIDQHHRNQCQYCRLKKCLKVGMRREAVQRGRMPPTQPTHGQFALTN 110 120 130 140 150 160 180 190 200 210 220 230 pF1KB8 GDPLNGHCYLSGYISLLLRAEPYPTSRYGSQCMQPNNIMGIENICELAARLLFSAVEWAR ::::: : :::::::::::::::::::.::::::::::::::::::::::.::::::::: CCDS10 GDPLNCHSYLSGYISLLLRAEPYPTSRFGSQCMQPNNIMGIENICELAARMLFSAVEWAR 170 180 190 200 210 220 240 250 260 270 280 290 pF1KB8 NIPFFPDLQITDQVSLLRLTWSELFVLNAAQCSMPLHVAPLLAAAGLHASPMSADRVVAF ::::::::::::::.::::::::::::::::::::::::::::::::::::::::::::: CCDS10 NIPFFPDLQITDQVALLRLTWSELFVLNAAQCSMPLHVAPLLAAAGLHASPMSADRVVAF 230 240 250 260 270 280 300 310 320 330 340 350 pF1KB8 MDHIRIFQEQVEKLKALHVDSAEYSCLKAIVLFTSDACGLSDAAHIESLQEKSQCALEEY ::::::::::::::::::::::::::::::::::::::::::.::.:::::::::::::: CCDS10 MDHIRIFQEQVEKLKALHVDSAEYSCLKAIVLFTSDACGLSDVAHVESLQEKSQCALEEY 290 300 310 320 330 340 360 370 380 390 400 410 pF1KB8 VRSQYPNQPSRFGKLLLRLPSLRTVSSSVIEQLFFVRLVGKTPIETLIRDMLLSGSSFNW :::::::::.:::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 VRSQYPNQPTRFGKLLLRLPSLRTVSSSVIEQLFFVRLVGKTPIETLIRDMLLSGSSFNW 350 360 370 380 390 400 420 pF1KB8 PYMSIQCS :::.:: CCDS10 PYMAIQ 410 >>CCDS45358.1 NR2F2 gene_id:7026|Hs108|chr15 (281 aa) initn: 1711 init1: 1711 opt: 1713 Z-score: 1112.8 bits: 214.3 E(32554): 1.2e-55 Smith-Waterman score: 1713; 93.5% identity (97.1% similar) in 275 aa overlap (147-421:7-281) 120 130 140 150 160 170 pF1KB8 NLTYTCRANRNCPIDQHHRNQCQYCRLKKCLKVGMRREAVQRGRMPPTQPNPGQYALTNG :. : ::::::::::::. ::.::::: CCDS45 MQAVWDLEQGKYGFAVQRGRMPPTQPTHGQFALTNG 10 20 30 180 190 200 210 220 230 pF1KB8 DPLNGHCYLSGYISLLLRAEPYPTSRYGSQCMQPNNIMGIENICELAARLLFSAVEWARN :::: : :::::::::::::::::::.::::::::::::::::::::::.:::::::::: CCDS45 DPLNCHSYLSGYISLLLRAEPYPTSRFGSQCMQPNNIMGIENICELAARMLFSAVEWARN 40 50 60 70 80 90 240 250 260 270 280 290 pF1KB8 IPFFPDLQITDQVSLLRLTWSELFVLNAAQCSMPLHVAPLLAAAGLHASPMSADRVVAFM :::::::::::::.:::::::::::::::::::::::::::::::::::::::::::::: CCDS45 IPFFPDLQITDQVALLRLTWSELFVLNAAQCSMPLHVAPLLAAAGLHASPMSADRVVAFM 100 110 120 130 140 150 300 310 320 330 340 350 pF1KB8 DHIRIFQEQVEKLKALHVDSAEYSCLKAIVLFTSDACGLSDAAHIESLQEKSQCALEEYV :::::::::::::::::::::::::::::::::::::::::.::.::::::::::::::: CCDS45 DHIRIFQEQVEKLKALHVDSAEYSCLKAIVLFTSDACGLSDVAHVESLQEKSQCALEEYV 160 170 180 190 200 210 360 370 380 390 400 410 pF1KB8 RSQYPNQPSRFGKLLLRLPSLRTVSSSVIEQLFFVRLVGKTPIETLIRDMLLSGSSFNWP ::::::::.::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 RSQYPNQPTRFGKLLLRLPSLRTVSSSVIEQLFFVRLVGKTPIETLIRDMLLSGSSFNWP 220 230 240 250 260 270 420 pF1KB8 YMSIQCS ::.:: CCDS45 YMAIQ 280 >>CCDS45359.1 NR2F2 gene_id:7026|Hs108|chr15 (261 aa) initn: 1672 init1: 1672 opt: 1672 Z-score: 1087.1 bits: 209.5 E(32554): 3.1e-54 Smith-Waterman score: 1672; 95.4% identity (98.9% similar) in 261 aa overlap (161-421:1-261) 140 150 160 170 180 190 pF1KB8 DQHHRNQCQYCRLKKCLKVGMRREAVQRGRMPPTQPNPGQYALTNGDPLNGHCYLSGYIS ::::::. ::.::::::::: : ::::::: CCDS45 MPPTQPTHGQFALTNGDPLNCHSYLSGYIS 10 20 30 200 210 220 230 240 250 pF1KB8 LLLRAEPYPTSRYGSQCMQPNNIMGIENICELAARLLFSAVEWARNIPFFPDLQITDQVS ::::::::::::.::::::::::::::::::::::.:::::::::::::::::::::::. CCDS45 LLLRAEPYPTSRFGSQCMQPNNIMGIENICELAARMLFSAVEWARNIPFFPDLQITDQVA 40 50 60 70 80 90 260 270 280 290 300 310 pF1KB8 LLRLTWSELFVLNAAQCSMPLHVAPLLAAAGLHASPMSADRVVAFMDHIRIFQEQVEKLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 LLRLTWSELFVLNAAQCSMPLHVAPLLAAAGLHASPMSADRVVAFMDHIRIFQEQVEKLK 100 110 120 130 140 150 320 330 340 350 360 370 pF1KB8 ALHVDSAEYSCLKAIVLFTSDACGLSDAAHIESLQEKSQCALEEYVRSQYPNQPSRFGKL :::::::::::::::::::::::::::.::.:::::::::::::::::::::::.::::: CCDS45 ALHVDSAEYSCLKAIVLFTSDACGLSDVAHVESLQEKSQCALEEYVRSQYPNQPTRFGKL 160 170 180 190 200 210 380 390 400 410 420 pF1KB8 LLRLPSLRTVSSSVIEQLFFVRLVGKTPIETLIRDMLLSGSSFNWPYMSIQCS ::::::::::::::::::::::::::::::::::::::::::::::::.:: CCDS45 LLRLPSLRTVSSSVIEQLFFVRLVGKTPIETLIRDMLLSGSSFNWPYMAIQ 220 230 240 250 260 >>CCDS12352.1 NR2F6 gene_id:2063|Hs108|chr19 (404 aa) initn: 1698 init1: 1089 opt: 1243 Z-score: 811.6 bits: 159.1 E(32554): 6.9e-39 Smith-Waterman score: 1713; 64.2% identity (82.0% similar) in 405 aa overlap (32-421:9-404) 10 20 30 40 50 pF1KB8 AMVVSSWRDPQDDVAGGNPGGPNPAAQAARGGGGGAGEQQQQAGSGAPHTPQ--TPGQPG :: :: . ..:: : :.. . . . :: CCDS12 MAMVTGGWGGPGGDTNGVDKAG-GYPRAAEDDSASPPG 10 20 30 60 70 80 90 100 110 pF1KB8 APATPGTAGDKGQGPPGSGQSQQHIECVVCGDKSSGKHYGQFTCEGCKSFFKRSVRRNLT : :. . ::. . :: ...:::::::::::::: :::::::::::::.::::. CCDS12 A-ASDAEPGDEER--PG-----LQVDCVVCGDKSSGKHYGVFTCEGCKSFFKRSIRRNLS 40 50 60 70 80 120 130 140 150 160 170 pF1KB8 YTCRANRNCPIDQHHRNQCQYCRLKKCLKVGMRREAVQRGRMPPTQPN---------PGQ ::::.::.: :::::::::::::::::..::::.:::::::.: . :. ::. CCDS12 YTCRSNRDCQIDQHHRNQCQYCRLKKCFRVGMRKEAVQRGRIPHSLPGAVAASSGSPPGS 90 100 110 120 130 140 180 190 200 210 220 pF1KB8 Y--ALTNGDPLNGHCYLSGYISLLLRAEPYPTS--RYGSQCMQPNNIMGIENICELAARL :...: : .: :. ::::::::.. :.:. . ..::.:.::::::: CCDS12 ALAAVASGGDLFPGQPVSELIAQLLRAEPYPAAAGRFGAGGGAAGAVLGIDNVCELAARL 150 160 170 180 190 200 230 240 250 260 270 280 pF1KB8 LFSAVEWARNIPFFPDLQITDQVSLLRLTWSELFVLNAAQCSMPLHVAPLLAAAGLHASP :::.:::::. ::::.: ..:::.::::.::::::::::: ..:::.:::::::::::.: CCDS12 LFSTVEWARHAPFFPELPVADQVALLRLSWSELFVLNAAQAALPLHTAPLLAAAGLHAAP 210 220 230 240 250 260 290 300 310 320 330 340 pF1KB8 MSADRVVAFMDHIRIFQEQVEKLKALHVDSAEYSCLKAIVLFTSDACGLSDAAHIESLQE :.:.:.:::::..: :::::.:: :.::::::.:::::.::: ::::::: ::.::::: CCDS12 MAAERAVAFMDQVRAFQEQVDKLGRLQVDSAEYGCLKAIALFTPDACGLSDPAHVESLQE 270 280 290 300 310 320 350 360 370 380 390 400 pF1KB8 KSQCALEEYVRSQYPNQPSRFGKLLLRLPSLRTVSSSVIEQLFFVRLVGKTPIETLIRDM :.: :: ::::.:::.::.:::.::::::.::.: .:.: ::::.::::::::::::::: CCDS12 KAQVALTEYVRAQYPSQPQRFGRLLLRLPALRAVPASLISQLFFMRLVGKTPIETLIRDM 330 340 350 360 370 380 410 420 pF1KB8 LLSGSSFNWPYMSIQCS :::::.::::: : : CCDS12 LLSGSTFNWPYGSGQ 390 400 >>CCDS1248.1 RXRG gene_id:6258|Hs108|chr1 (463 aa) initn: 793 init1: 392 opt: 976 Z-score: 640.8 bits: 127.7 E(32554): 2.2e-29 Smith-Waterman score: 976; 40.0% identity (67.3% similar) in 413 aa overlap (11-407:53-456) 10 20 30 pF1KB8 MAMVVSSWRDPQDDVAGGNP----GGPNPAAQAARGGGGG :. : :.: :.: . .: : .: CCDS12 GSTSMSPSAALSTGKPMDSHPSYTDTPVSAPRTLSAVGTPLNALGSPYRVITSAMGPPSG 30 40 50 60 70 80 40 50 60 70 80 pF1KB8 AGEQQQQAGSGAPHTPQ------TPGQPGAPATPGTAGDKGQGPPGS--GQSQQHIECVV : . :: . : . .. :: : ... :.. :. .:: :.. CCDS12 ALAAPPGINLVAPPSSQLNVVNSVSSSEDIKPLPGLPGIGNMNYPSTSPGSLVKHI-CAI 90 100 110 120 130 140 90 100 110 120 130 140 pF1KB8 CGDKSSGKHYGQFTCEGCKSFFKRSVRRNLTYTCRANRNCPIDQHHRNQCQYCRLKKCLK :::.::::::: ..:::::.::::..:..: :::: :..: ::...::.::::: .::: CCDS12 CGDRSSGKHYGVYSCEGCKGFFKRTIRKDLIYTCRDNKDCLIDKRQRNRCQYCRYQKCLV 150 160 170 180 190 200 150 160 170 180 190 200 pF1KB8 VGMRREAVQ--RGRMPPTQPNPGQYALTNGDPLNGHCYLSGYISLLLRAEPYPTSRYGSQ .::.::::: : : . .. : .. . . . : . ... :: : ::.. CCDS12 MGMKREAVQEERQRSRERAESEAECATSGHEDMPVERILEAELAV----EP-KTESYGDM 210 220 230 240 250 210 220 230 240 250 260 pF1KB8 CMQPNNIMGIENICELAARLLFSAVEWARNIPFFPDLQITDQVSLLRLTWSELFVLNAAQ :. .. . :::. : . ::. ::::. :: : :: . ::: ::: :.::.. . .. CCDS12 NMENSTNDPVTNICHAADKQLFTLVEWAKRIPHFSDLTLEDQVILLRAGWNELLIASFSH 260 270 280 290 300 310 270 280 290 300 310 320 pF1KB8 CSMPLHVAPLLAAAGLHASPMSADR--VVAFMDHIRIFQEQVEKLKALHVDSAEYSCLKA :. .. . :::. :::. :: : ...: :.. : : :.: ...:..: .::.: CCDS12 RSVSVQDGILLAT-GLHVHRSSAHSAGVGSIFD--RVLTELVSKMKDMQMDKSELGCLRA 320 330 340 350 360 370 330 340 350 360 370 380 pF1KB8 IVLFTSDACGLSDAAHIESLQEKSQCALEEYVRSQYPNQPSRFGKLLLRLPSLRTVSSSV ::::. :: :::. ...:.:.:: .:: :....::.::.::.:::::::.::... . CCDS12 IVLFNPDAKGLSNPSEVETLREKVYATLEAYTKQKYPEQPGRFAKLLLRLPALRSIGLKC 380 390 400 410 420 430 390 400 410 420 pF1KB8 IEQLFFVRLVGKTPIETLIRDMLLSGSSFNWPYMSIQCS .:.::: .:.: :::.:.. .:: CCDS12 LEHLFFFKLIGDTPIDTFLMEMLETPLQIT 440 450 460 >>CCDS4768.1 RXRB gene_id:6257|Hs108|chr6 (533 aa) initn: 744 init1: 651 opt: 976 Z-score: 640.2 bits: 127.8 E(32554): 2.5e-29 Smith-Waterman score: 976; 39.6% identity (68.4% similar) in 396 aa overlap (18-407:141-526) 10 20 30 40 pF1KB8 MAMVVSSWRDPQDDVAGGNPGGPNPAAQAARGGGGGAGEQQQQAGSG :.:: : :: : .: .. : .. . CCDS47 PSLGGSGAPPPPPMPPPPLGSPFPVISSSMGSPGLPPPAPP---GFSGPVSSPQINSTVS 120 130 140 150 160 50 60 70 80 90 100 pF1KB8 APHTPQTPGQPGAPATPGTAGDKGQGPPGSGQSQQHIECVVCGDKSSGKHYGQFTCEGCK : . : . : . :. : . :::. . ... :..:::.::::::: ..::::: CCDS47 LPGGGSGPPEDVKPPVLGVRGLHCPPPPGGPGAGKRL-CAICGDRSSGKHYGVYSCEGCK 170 180 190 200 210 220 110 120 130 140 150 160 pF1KB8 SFFKRSVRRNLTYTCRANRNCPIDQHHRNQCQYCRLKKCLKVGMRREAVQRGRM-PPTQP .::::..:..:::.:: :..: .:...::.::::: .::: .::.:::::. :. . CCDS47 GFFKRTIRKDLTYSCRDNKDCTVDKRQRNRCQYCRYQKCLATGMKREAVQEERQRGKDKD 230 240 250 260 270 280 170 180 190 200 210 220 pF1KB8 NPGQYALTNGDPLNGHCYLSGYISLLLRAEPY---PTSRYGSQCMQPNNIMGIENICELA . :. : . . : . ... ... : . :: .::. . :::. : CCDS47 GDGEGAGGAPEEMPVDRILEAELAVEQKSDQGVEGPGGTGGSGS-SPND--PVTNICQAA 290 300 310 320 330 340 230 240 250 260 270 280 pF1KB8 ARLLFSAVEWARNIPFFPDLQITDQVSLLRLTWSELFVLNAAQCSMPLHVAPLLAAAGLH . ::. ::::. :: : .: . ::: ::: :.::.. . .. :. .. . :::. ::: CCDS47 DKQLFTLVEWAKRIPHFSSLPLDDQVILLRAGWNELLIASFSHRSIDVRDGILLAT-GLH 350 360 370 380 390 400 290 300 310 320 330 340 pF1KB8 ASPMSADR--VVAFMDHIRIFQEQVEKLKALHVDSAEYSCLKAIVLFTSDACGLSDAAHI . :: : :..: :.. : : :.. ...:..: .::.::.::. :: :::. ... CCDS47 VHRNSAHSAGVGAIFD--RVLTELVSKMRDMRMDKTELGCLRAIILFNPDAKGLSNPSEV 410 420 430 440 450 460 350 360 370 380 390 400 pF1KB8 ESLQEKSQCALEEYVRSQYPNQPSRFGKLLLRLPSLRTVSSSVIEQLFFVRLVGKTPIET : :.:: .:: : ...::.: .::.:::::::.::... . .:.::: .:.: :::.: CCDS47 EVLREKVYASLETYCKQKYPEQQGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDT 470 480 490 500 510 520 410 420 pF1KB8 LIRDMLLSGSSFNWPYMSIQCS .. .:: CCDS47 FLMEMLEAPHQLA 530 >>CCDS35172.1 RXRA gene_id:6256|Hs108|chr9 (462 aa) initn: 584 init1: 538 opt: 972 Z-score: 638.3 bits: 127.3 E(32554): 3.1e-29 Smith-Waterman score: 972; 42.1% identity (70.2% similar) in 373 aa overlap (46-407:89-455) 20 30 40 50 60 pF1KB8 AGGNPGGPNPAAQAARGGGGGAGEQQQQAGSGAPH--TPQTPGQPGAPATP--GTAG--D .:.:. .:..: . . : : : CCDS35 NGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLK 60 70 80 90 100 110 70 80 90 100 110 120 pF1KB8 KGQGPPGSGQS-QQHIECVVCGDKSSGKHYGQFTCEGCKSFFKRSVRRNLTYTCRANRNC : :. : .:: :..:::.::::::: ..:::::.::::.::..:::::: :..: CCDS35 VPAHPSGNMASFTKHI-CAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDC 120 130 140 150 160 170 130 140 150 160 170 180 pF1KB8 PIDQHHRNQCQYCRLKKCLKVGMRREAVQ--RGRMPPTQPNPGQYALTNGDPLNGHCYLS ::...::.::::: .::: .::.::::: : : . : . . . .. . . : CCDS35 LIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILE 180 190 200 210 220 230 190 200 210 220 230 240 pF1KB8 GYISLLLRAEPYPTSRYGSQCMQPNNIMGIENICELAARLLFSAVEWARNIPFFPDLQIT . ... ..: : . .: . .::. . :::. : . ::. ::::. :: : .: . CCDS35 AELAVEPKTETYVEANMGLNPSSPND--PVTNICQAADKQLFTLVEWAKRIPHFSELPLD 240 250 260 270 280 290 250 260 270 280 290 300 pF1KB8 DQVSLLRLTWSELFVLNAAQCSMPLHVAPLLAAAGLHASPMSADR--VVAFMDHIRIFQE ::: ::: :.::.. . .. :. .. . :::. :::. :: : :..: :.. : CCDS35 DQVILLRAGWNELLIASFSHRSIAVKDGILLAT-GLHVHRNSAHSAGVGAIFD--RVLTE 300 310 320 330 340 350 310 320 330 340 350 360 pF1KB8 QVEKLKALHVDSAEYSCLKAIVLFTSDACGLSDAAHIESLQEKSQCALEEYVRSQYPNQP : :.. ...:..: .::.:::::. :. :::. :..:.:.:: .:: : . .::.:: CCDS35 LVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQP 360 370 380 390 400 410 370 380 390 400 410 420 pF1KB8 SRFGKLLLRLPSLRTVSSSVIEQLFFVRLVGKTPIETLIRDMLLSGSSFNWPYMSIQCS .::.:::::::.::... . .:.::: .:.: :::.:.. .:: CCDS35 GRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT 420 430 440 450 460 >>CCDS59007.1 RXRB gene_id:6257|Hs108|chr6 (537 aa) initn: 1021 init1: 426 opt: 973 Z-score: 638.2 bits: 127.5 E(32554): 3.2e-29 Smith-Waterman score: 973; 39.4% identity (68.3% similar) in 398 aa overlap (18-407:141-530) 10 20 30 40 pF1KB8 MAMVVSSWRDPQDDVAGGNPGGPNPAAQAARGGGGGAGEQQQQAGSG :.:: : :: : .: .. : .. . CCDS59 PSLGGSGAPPPPPMPPPPLGSPFPVISSSMGSPGLPPPAPP---GFSGPVSSPQINSTVS 120 130 140 150 160 50 60 70 80 90 100 pF1KB8 APHTPQTPGQPGAPATPGTAGDKGQGPPGSGQSQQHIECVVCGDKSSGKHYGQFTCEGCK : . : . : . :. : . :::. . ... :..:::.::::::: ..::::: CCDS59 LPGGGSGPPEDVKPPVLGVRGLHCPPPPGGPGAGKRL-CAICGDRSSGKHYGVYSCEGCK 170 180 190 200 210 220 110 120 130 140 150 160 pF1KB8 SFFKRSVRRNLTYTCRANRNCPIDQHHRNQCQYCRLKKCLKVGMRREAVQRGRM-PPTQP .::::..:..:::.:: :..: .:...::.::::: .::: .::.:::::. :. . CCDS59 GFFKRTIRKDLTYSCRDNKDCTVDKRQRNRCQYCRYQKCLATGMKREAVQEERQRGKDKD 230 240 250 260 270 280 170 180 190 200 210 220 pF1KB8 NPGQYALTNGDPLNGHCYLSGYISLLLRAEPY---PTSRYGSQCMQPNNIMGIENICELA . :. : . . : . ... ... : . :: .::. . :::. : CCDS59 GDGEGAGGAPEEMPVDRILEAELAVEQKSDQGVEGPGGTGGSGS-SPND--PVTNICQAA 290 300 310 320 330 340 230 240 250 260 270 280 pF1KB8 ARLLFSAVEWARNIPFFPDLQITDQVSLLRLTWSELFVLNAAQCSMPLHVAPLLAAAGLH . ::. ::::. :: : .: . ::: ::: :.::.. . .. :. .. . :::. ::: CCDS59 DKQLFTLVEWAKRIPHFSSLPLDDQVILLRAGWNELLIASFSHRSIDVRDGILLAT-GLH 350 360 370 380 390 400 290 300 310 320 330 pF1KB8 ASPMSADR--VVAFMDHI--RIFQEQVEKLKALHVDSAEYSCLKAIVLFTSDACGLSDAA . :: : :..:. :.. : : :.. ...:..: .::.::.::. :: :::. . CCDS59 VHRNSAHSAGVGAIFDRSLSRVLTELVSKMRDMRMDKTELGCLRAIILFNPDAKGLSNPS 410 420 430 440 450 460 340 350 360 370 380 390 pF1KB8 HIESLQEKSQCALEEYVRSQYPNQPSRFGKLLLRLPSLRTVSSSVIEQLFFVRLVGKTPI ..: :.:: .:: : ...::.: .::.:::::::.::... . .:.::: .:.: ::: CCDS59 EVEVLREKVYASLETYCKQKYPEQQGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPI 470 480 490 500 510 520 400 410 420 pF1KB8 ETLIRDMLLSGSSFNWPYMSIQCS .:.. .:: CCDS59 DTFLMEMLEAPHQLA 530 >>CCDS72970.1 RXRG gene_id:6258|Hs108|chr1 (340 aa) initn: 793 init1: 392 opt: 953 Z-score: 627.7 bits: 124.9 E(32554): 1.2e-28 Smith-Waterman score: 953; 44.5% identity (73.0% similar) in 337 aa overlap (75-407:8-333) 50 60 70 80 90 100 pF1KB8 GSGAPHTPQTPGQPGAPATPGTAGDKGQGPPGSGQSQQHIECVVCGDKSSGKHYGQFTCE ::: .:: :..:::.::::::: ..:: CCDS72 MNYPSTSPGS--LVKHI-CAICGDRSSGKHYGVYSCE 10 20 30 110 120 130 140 150 160 pF1KB8 GCKSFFKRSVRRNLTYTCRANRNCPIDQHHRNQCQYCRLKKCLKVGMRREAVQ--RGRMP :::.::::..:..: :::: :..: ::...::.::::: .::: .::.::::: : : CCDS72 GCKGFFKRTIRKDLIYTCRDNKDCLIDKRQRNRCQYCRYQKCLVMGMKREAVQEERQRSR 40 50 60 70 80 90 170 180 190 200 210 220 pF1KB8 PTQPNPGQYALTNGDPLNGHCYLSGYISLLLRAEPYPTSRYGSQCMQPNNIMGIENICEL . .. : .. . . . : . ... :: : ::.. :. .. . :::. CCDS72 ERAESEAECATSGHEDMPVERILEAELAV----EP-KTESYGDMNMENSTNDPVTNICHA 100 110 120 130 140 230 240 250 260 270 280 pF1KB8 AARLLFSAVEWARNIPFFPDLQITDQVSLLRLTWSELFVLNAAQCSMPLHVAPLLAAAGL : . ::. ::::. :: : :: . ::: ::: :.::.. . .. :. .. . :::. :: CCDS72 ADKQLFTLVEWAKRIPHFSDLTLEDQVILLRAGWNELLIASFSHRSVSVQDGILLAT-GL 150 160 170 180 190 200 290 300 310 320 330 340 pF1KB8 HASPMSADR--VVAFMDHIRIFQEQVEKLKALHVDSAEYSCLKAIVLFTSDACGLSDAAH :. :: : ...: :.. : : :.: ...:..: .::.:::::. :: :::. .. CCDS72 HVHRSSAHSAGVGSIFD--RVLTELVSKMKDMQMDKSELGCLRAIVLFNPDAKGLSNPSE 210 220 230 240 250 260 350 360 370 380 390 400 pF1KB8 IESLQEKSQCALEEYVRSQYPNQPSRFGKLLLRLPSLRTVSSSVIEQLFFVRLVGKTPIE .:.:.:: .:: :....::.::.::.:::::::.::... . .:.::: .:.: :::. CCDS72 VETLREKVYATLEAYTKQKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPID 270 280 290 300 310 320 410 420 pF1KB8 TLIRDMLLSGSSFNWPYMSIQCS :.. .:: CCDS72 TFLMEMLETPLQIT 330 340 423 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 12:27:12 2016 done: Fri Nov 4 12:27:13 2016 Total Scan time: 3.440 Total Display time: 0.060 Function used was FASTA [36.3.4 Apr, 2011]