FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB8388, 582 aa 1>>>pF1KB8388 582 - 582 aa - 582 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 15.4869+/-0.00045; mu= -25.2953+/- 0.028 mean_var=752.6338+/-153.769, 0's: 0 Z-trim(126.1): 47 B-trim: 0 in 0/61 Lambda= 0.046750 statistics sampled from 51310 (51375) to 51310 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.83), E-opt: 0.2 (0.602), width: 16 Scan time: 11.440 The best scores are: opt bits E(85289) NP_064706 (OMIM: 603039) max-binding protein MNT [ ( 582) 3962 282.2 3.2e-75 XP_011522170 (OMIM: 603039) PREDICTED: max-binding ( 590) 3803 271.5 5.5e-72 XP_016880143 (OMIM: 603039) PREDICTED: max-binding ( 301) 2045 152.7 1.7e-36 XP_011522171 (OMIM: 603039) PREDICTED: max-binding ( 301) 2045 152.7 1.7e-36 >>NP_064706 (OMIM: 603039) max-binding protein MNT [Homo (582 aa) initn: 3962 init1: 3962 opt: 3962 Z-score: 1471.4 bits: 282.2 E(85289): 3.2e-75 Smith-Waterman score: 3962; 100.0% identity (100.0% similar) in 582 aa overlap (1-582:1-582) 10 20 30 40 50 60 pF1KB8 MSIETLLEAARFLEWQAQQQQRAREEQERLRLEQEREQEQKKANSLARLAHTLPVEEPRM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_064 MSIETLLEAARFLEWQAQQQQRAREEQERLRLEQEREQEQKKANSLARLAHTLPVEEPRM 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 EAPPLPLSPPAPPPAPPPPLATPAPLTVIPIPVVTNSPQPLPPPPPLPAAAQPLPLAPRQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_064 EAPPLPLSPPAPPPAPPPPLATPAPLTVIPIPVVTNSPQPLPPPPPLPAAAQPLPLAPRQ 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 PALVGAPGLSIKEPAPLPSRPQVPTPAPLLPDSKATIPPNGSPKPLQPLPTPVLTIAPHP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_064 PALVGAPGLSIKEPAPLPSRPQVPTPAPLLPDSKATIPPNGSPKPLQPLPTPVLTIAPHP 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 GVQPQLAPQQPPPPTLGTLKLAPAEEVKSSEQKKRPGGIGTREVHNKLEKNRRAHLKECF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_064 GVQPQLAPQQPPPPTLGTLKLAPAEEVKSSEQKKRPGGIGTREVHNKLEKNRRAHLKECF 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 ETLKRNIPNVDDKKTSNLSVLRTALRYIQSLKRKEKEYEHEMERLAREKIATQQRLAELK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_064 ETLKRNIPNVDDKKTSNLSVLRTALRYIQSLKRKEKEYEHEMERLAREKIATQQRLAELK 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 HELSQWMDVLEIDRVLRQTGQPEDDQASTSTASEGEDNIDEDMEEDRAGLGPPKLSHRPQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_064 HELSQWMDVLEIDRVLRQTGQPEDDQASTSTASEGEDNIDEDMEEDRAGLGPPKLSHRPQ 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB8 PELLKSTLPPPSTTPAPLPPHPHPHPHSVALPPAHLPVQQQQPQQKTPLPAPPPPPAAPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_064 PELLKSTLPPPSTTPAPLPPHPHPHPHSVALPPAHLPVQQQQPQQKTPLPAPPPPPAAPA 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB8 QTLVPAPAHLVATAGGGSTVIAHTATTHASVIQTVNHVLQGPGGKHIAHIAPSAPSPAVQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_064 QTLVPAPAHLVATAGGGSTVIAHTATTHASVIQTVNHVLQGPGGKHIAHIAPSAPSPAVQ 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB8 LAPATPPIGHITVHPATLNHVAHLGSQLPLYPQPVAVSHIAHTLSHQQVNGTAGLGPPAT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_064 LAPATPPIGHITVHPATLNHVAHLGSQLPLYPQPVAVSHIAHTLSHQQVNGTAGLGPPAT 490 500 510 520 530 540 550 560 570 580 pF1KB8 VMAKPAVGAQVVHHPQLVGQTVLNPVTMVTMPSFPVSTLKLA :::::::::::::::::::::::::::::::::::::::::: NP_064 VMAKPAVGAQVVHHPQLVGQTVLNPVTMVTMPSFPVSTLKLA 550 560 570 580 >>XP_011522170 (OMIM: 603039) PREDICTED: max-binding pro (590 aa) initn: 3803 init1: 3803 opt: 3803 Z-score: 1413.4 bits: 271.5 E(85289): 5.5e-72 Smith-Waterman score: 3803; 99.8% identity (100.0% similar) in 558 aa overlap (25-582:33-590) 10 20 30 40 50 pF1KB8 MSIETLLEAARFLEWQAQQQQRAREEQERLRLEQEREQEQKKANSLARLAHTLP .::::::::::::::::::::::::::::: XP_011 YVWAQGSGEDRAQGSERLSHLLPPSTRCSSKEQERLRLEQEREQEQKKANSLARLAHTLP 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB8 VEEPRMEAPPLPLSPPAPPPAPPPPLATPAPLTVIPIPVVTNSPQPLPPPPPLPAAAQPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VEEPRMEAPPLPLSPPAPPPAPPPPLATPAPLTVIPIPVVTNSPQPLPPPPPLPAAAQPL 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB8 PLAPRQPALVGAPGLSIKEPAPLPSRPQVPTPAPLLPDSKATIPPNGSPKPLQPLPTPVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PLAPRQPALVGAPGLSIKEPAPLPSRPQVPTPAPLLPDSKATIPPNGSPKPLQPLPTPVL 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB8 TIAPHPGVQPQLAPQQPPPPTLGTLKLAPAEEVKSSEQKKRPGGIGTREVHNKLEKNRRA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TIAPHPGVQPQLAPQQPPPPTLGTLKLAPAEEVKSSEQKKRPGGIGTREVHNKLEKNRRA 190 200 210 220 230 240 240 250 260 270 280 290 pF1KB8 HLKECFETLKRNIPNVDDKKTSNLSVLRTALRYIQSLKRKEKEYEHEMERLAREKIATQQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HLKECFETLKRNIPNVDDKKTSNLSVLRTALRYIQSLKRKEKEYEHEMERLAREKIATQQ 250 260 270 280 290 300 300 310 320 330 340 350 pF1KB8 RLAELKHELSQWMDVLEIDRVLRQTGQPEDDQASTSTASEGEDNIDEDMEEDRAGLGPPK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RLAELKHELSQWMDVLEIDRVLRQTGQPEDDQASTSTASEGEDNIDEDMEEDRAGLGPPK 310 320 330 340 350 360 360 370 380 390 400 410 pF1KB8 LSHRPQPELLKSTLPPPSTTPAPLPPHPHPHPHSVALPPAHLPVQQQQPQQKTPLPAPPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LSHRPQPELLKSTLPPPSTTPAPLPPHPHPHPHSVALPPAHLPVQQQQPQQKTPLPAPPP 370 380 390 400 410 420 420 430 440 450 460 470 pF1KB8 PPAAPAQTLVPAPAHLVATAGGGSTVIAHTATTHASVIQTVNHVLQGPGGKHIAHIAPSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PPAAPAQTLVPAPAHLVATAGGGSTVIAHTATTHASVIQTVNHVLQGPGGKHIAHIAPSA 430 440 450 460 470 480 480 490 500 510 520 530 pF1KB8 PSPAVQLAPATPPIGHITVHPATLNHVAHLGSQLPLYPQPVAVSHIAHTLSHQQVNGTAG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PSPAVQLAPATPPIGHITVHPATLNHVAHLGSQLPLYPQPVAVSHIAHTLSHQQVNGTAG 490 500 510 520 530 540 540 550 560 570 580 pF1KB8 LGPPATVMAKPAVGAQVVHHPQLVGQTVLNPVTMVTMPSFPVSTLKLA :::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LGPPATVMAKPAVGAQVVHHPQLVGQTVLNPVTMVTMPSFPVSTLKLA 550 560 570 580 590 >>XP_016880143 (OMIM: 603039) PREDICTED: max-binding pro (301 aa) initn: 2045 init1: 2045 opt: 2045 Z-score: 776.4 bits: 152.7 E(85289): 1.7e-36 Smith-Waterman score: 2045; 100.0% identity (100.0% similar) in 301 aa overlap (282-582:1-301) 260 270 280 290 300 310 pF1KB8 DKKTSNLSVLRTALRYIQSLKRKEKEYEHEMERLAREKIATQQRLAELKHELSQWMDVLE :::::::::::::::::::::::::::::: XP_016 MERLAREKIATQQRLAELKHELSQWMDVLE 10 20 30 320 330 340 350 360 370 pF1KB8 IDRVLRQTGQPEDDQASTSTASEGEDNIDEDMEEDRAGLGPPKLSHRPQPELLKSTLPPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IDRVLRQTGQPEDDQASTSTASEGEDNIDEDMEEDRAGLGPPKLSHRPQPELLKSTLPPP 40 50 60 70 80 90 380 390 400 410 420 430 pF1KB8 STTPAPLPPHPHPHPHSVALPPAHLPVQQQQPQQKTPLPAPPPPPAAPAQTLVPAPAHLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 STTPAPLPPHPHPHPHSVALPPAHLPVQQQQPQQKTPLPAPPPPPAAPAQTLVPAPAHLV 100 110 120 130 140 150 440 450 460 470 480 490 pF1KB8 ATAGGGSTVIAHTATTHASVIQTVNHVLQGPGGKHIAHIAPSAPSPAVQLAPATPPIGHI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ATAGGGSTVIAHTATTHASVIQTVNHVLQGPGGKHIAHIAPSAPSPAVQLAPATPPIGHI 160 170 180 190 200 210 500 510 520 530 540 550 pF1KB8 TVHPATLNHVAHLGSQLPLYPQPVAVSHIAHTLSHQQVNGTAGLGPPATVMAKPAVGAQV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TVHPATLNHVAHLGSQLPLYPQPVAVSHIAHTLSHQQVNGTAGLGPPATVMAKPAVGAQV 220 230 240 250 260 270 560 570 580 pF1KB8 VHHPQLVGQTVLNPVTMVTMPSFPVSTLKLA ::::::::::::::::::::::::::::::: XP_016 VHHPQLVGQTVLNPVTMVTMPSFPVSTLKLA 280 290 300 >>XP_011522171 (OMIM: 603039) PREDICTED: max-binding pro (301 aa) initn: 2045 init1: 2045 opt: 2045 Z-score: 776.4 bits: 152.7 E(85289): 1.7e-36 Smith-Waterman score: 2045; 100.0% identity (100.0% similar) in 301 aa overlap (282-582:1-301) 260 270 280 290 300 310 pF1KB8 DKKTSNLSVLRTALRYIQSLKRKEKEYEHEMERLAREKIATQQRLAELKHELSQWMDVLE :::::::::::::::::::::::::::::: XP_011 MERLAREKIATQQRLAELKHELSQWMDVLE 10 20 30 320 330 340 350 360 370 pF1KB8 IDRVLRQTGQPEDDQASTSTASEGEDNIDEDMEEDRAGLGPPKLSHRPQPELLKSTLPPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IDRVLRQTGQPEDDQASTSTASEGEDNIDEDMEEDRAGLGPPKLSHRPQPELLKSTLPPP 40 50 60 70 80 90 380 390 400 410 420 430 pF1KB8 STTPAPLPPHPHPHPHSVALPPAHLPVQQQQPQQKTPLPAPPPPPAAPAQTLVPAPAHLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 STTPAPLPPHPHPHPHSVALPPAHLPVQQQQPQQKTPLPAPPPPPAAPAQTLVPAPAHLV 100 110 120 130 140 150 440 450 460 470 480 490 pF1KB8 ATAGGGSTVIAHTATTHASVIQTVNHVLQGPGGKHIAHIAPSAPSPAVQLAPATPPIGHI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ATAGGGSTVIAHTATTHASVIQTVNHVLQGPGGKHIAHIAPSAPSPAVQLAPATPPIGHI 160 170 180 190 200 210 500 510 520 530 540 550 pF1KB8 TVHPATLNHVAHLGSQLPLYPQPVAVSHIAHTLSHQQVNGTAGLGPPATVMAKPAVGAQV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TVHPATLNHVAHLGSQLPLYPQPVAVSHIAHTLSHQQVNGTAGLGPPATVMAKPAVGAQV 220 230 240 250 260 270 560 570 580 pF1KB8 VHHPQLVGQTVLNPVTMVTMPSFPVSTLKLA ::::::::::::::::::::::::::::::: XP_011 VHHPQLVGQTVLNPVTMVTMPSFPVSTLKLA 280 290 300 582 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 12:28:35 2016 done: Fri Nov 4 12:28:36 2016 Total Scan time: 11.440 Total Display time: 0.020 Function used was FASTA [36.3.4 Apr, 2011]