FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB8399, 227 aa
  1>>>pF1KB8399 227 - 227 aa - 227 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 6.7068+/-0.000295; mu= 9.6608+/- 0.018
 mean_var=147.4793+/-31.154, 0's: 0 Z-trim(122.1): 111  B-trim: 4299 in 2/55
 Lambda= 0.105611
 statistics sampled from 39687 (39811) to 39687 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.792), E-opt: 0.2 (0.467), width:  16
 Scan time:  5.650

The best scores are:                                      opt bits E(85289)
XP_016879282 (OMIM: 612060) PREDICTED: E3 ubiquiti ( 227) 1611 256.0 3.7e-68
NP_115644 (OMIM: 612060) E3 ubiquitin-protein liga ( 227) 1611 256.0 3.7e-68
XP_011521694 (OMIM: 612060) PREDICTED: E3 ubiquiti ( 142)  992 161.5 6.6e-40
XP_016879283 (OMIM: 612060) PREDICTED: E3 ubiquiti ( 183)  984 160.4 1.8e-39
NP_667339 (OMIM: 612061) E3 ubiquitin-protein liga ( 242)  609 103.4 3.5e-22


>>XP_016879282 (OMIM: 612060) PREDICTED: E3 ubiquitin-pr  (227 aa)
 initn: 1611 init1: 1611 opt: 1611  Z-score: 1344.6  bits: 256.0 E(85289): 3.7e-68
Smith-Waterman score: 1611; 100.0% identity (100.0% similar) in 227 aa overlap (1-227:1-227)

               10        20        30        40        50        60
pF1KB8 MGGKQSTAARSRGPFPGVSTDDSAVPPPGGAPHFGHYRTGGGAMGLRSRSVSSVAGMGMD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MGGKQSTAARSRGPFPGVSTDDSAVPPPGGAPHFGHYRTGGGAMGLRSRSVSSVAGMGMD
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB8 PSTAGGVPFGLYTPASRGTGDSERAPGGGGSASDSTYAHGNGYQETGGGHHRDGMLYLGS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PSTAGGVPFGLYTPASRGTGDSERAPGGGGSASDSTYAHGNGYQETGGGHHRDGMLYLGS
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB8 RASLADALPLHIAPRWFSSHSGFKCPICSKSVASDEMEMHFIMCLSKPRLSYNDDVLTKD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RASLADALPLHIAPRWFSSHSGFKCPICSKSVASDEMEMHFIMCLSKPRLSYNDDVLTKD
              130       140       150       160       170       180

              190       200       210       220       
pF1KB8 AGECVICLEELLQGDTIARLPCLCIYHKSCIDSWFEVNRSCPEHPAD
       :::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AGECVICLEELLQGDTIARLPCLCIYHKSCIDSWFEVNRSCPEHPAD
              190       200       210       220       

>>NP_115644 (OMIM: 612060) E3 ubiquitin-protein ligase Z  (227 aa)
 initn: 1611 init1: 1611 opt: 1611  Z-score: 1344.6  bits: 256.0 E(85289): 3.7e-68
Smith-Waterman score: 1611; 100.0% identity (100.0% similar) in 227 aa overlap (1-227:1-227)

               10        20        30        40        50        60
pF1KB8 MGGKQSTAARSRGPFPGVSTDDSAVPPPGGAPHFGHYRTGGGAMGLRSRSVSSVAGMGMD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 MGGKQSTAARSRGPFPGVSTDDSAVPPPGGAPHFGHYRTGGGAMGLRSRSVSSVAGMGMD
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB8 PSTAGGVPFGLYTPASRGTGDSERAPGGGGSASDSTYAHGNGYQETGGGHHRDGMLYLGS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 PSTAGGVPFGLYTPASRGTGDSERAPGGGGSASDSTYAHGNGYQETGGGHHRDGMLYLGS
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB8 RASLADALPLHIAPRWFSSHSGFKCPICSKSVASDEMEMHFIMCLSKPRLSYNDDVLTKD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 RASLADALPLHIAPRWFSSHSGFKCPICSKSVASDEMEMHFIMCLSKPRLSYNDDVLTKD
              130       140       150       160       170       180

              190       200       210       220       
pF1KB8 AGECVICLEELLQGDTIARLPCLCIYHKSCIDSWFEVNRSCPEHPAD
       :::::::::::::::::::::::::::::::::::::::::::::::
NP_115 AGECVICLEELLQGDTIARLPCLCIYHKSCIDSWFEVNRSCPEHPAD
              190       200       210       220       

>>XP_011521694 (OMIM: 612060) PREDICTED: E3 ubiquitin-pr  (142 aa)
 initn: 992 init1: 992 opt: 992  Z-score: 837.5  bits: 161.5 E(85289): 6.6e-40
Smith-Waterman score: 992; 100.0% identity (100.0% similar) in 142 aa overlap (1-142:1-142)

               10        20        30        40        50        60
pF1KB8 MGGKQSTAARSRGPFPGVSTDDSAVPPPGGAPHFGHYRTGGGAMGLRSRSVSSVAGMGMD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MGGKQSTAARSRGPFPGVSTDDSAVPPPGGAPHFGHYRTGGGAMGLRSRSVSSVAGMGMD
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB8 PSTAGGVPFGLYTPASRGTGDSERAPGGGGSASDSTYAHGNGYQETGGGHHRDGMLYLGS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PSTAGGVPFGLYTPASRGTGDSERAPGGGGSASDSTYAHGNGYQETGGGHHRDGMLYLGS
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB8 RASLADALPLHIAPRWFSSHSGFKCPICSKSVASDEMEMHFIMCLSKPRLSYNDDVLTKD
       ::::::::::::::::::::::                                      
XP_011 RASLADALPLHIAPRWFSSHSG                                      
              130       140                                        

>>XP_016879283 (OMIM: 612060) PREDICTED: E3 ubiquitin-pr  (183 aa)
 initn: 984 init1: 984 opt: 984  Z-score: 829.5  bits: 160.4 E(85289): 1.8e-39
Smith-Waterman score: 984; 100.0% identity (100.0% similar) in 141 aa overlap (1-141:1-141)

               10        20        30        40        50        60
pF1KB8 MGGKQSTAARSRGPFPGVSTDDSAVPPPGGAPHFGHYRTGGGAMGLRSRSVSSVAGMGMD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MGGKQSTAARSRGPFPGVSTDDSAVPPPGGAPHFGHYRTGGGAMGLRSRSVSSVAGMGMD
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB8 PSTAGGVPFGLYTPASRGTGDSERAPGGGGSASDSTYAHGNGYQETGGGHHRDGMLYLGS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PSTAGGVPFGLYTPASRGTGDSERAPGGGGSASDSTYAHGNGYQETGGGHHRDGMLYLGS
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB8 RASLADALPLHIAPRWFSSHSGFKCPICSKSVASDEMEMHFIMCLSKPRLSYNDDVLTKD
       :::::::::::::::::::::                                       
XP_016 RASLADALPLHIAPRWFSSHSDESSCAALVPSHLKQTMGSSRTSVSSVTHCCKKQNLFLL
              130       140       150       160       170       180

>>NP_667339 (OMIM: 612061) E3 ubiquitin-protein ligase Z  (242 aa)
 initn: 646 init1: 553 opt: 609  Z-score: 519.1  bits: 103.4 E(85289): 3.5e-22
Smith-Waterman score: 664; 45.6% identity (65.3% similar) in 248 aa overlap (1-227:1-242)

               10        20        30        40        50        60
pF1KB8 MGGKQSTAARSRGPFPGVSTDDSAVPPPGGAPHFGHYRTGGGAMGLRSRSVSSVAGMGMD
       ::.:::  : . :   . : .:      :::   :    :::: .  .    . .  . .
NP_667 MGAKQSGPAAANGRTRAYSGSDLPSSSSGGAN--GTAGGGGGARAAAAGRFPAQVPSAHQ
               10        20        30          40        50        

                     70        80        90       100              
pF1KB8 PSTAGGV------PFGLYTPASRGTGDSERAPGGGGSASDSTYAHGN------GYQET--
       ::..::.      : .  .: ::. : .  . ..:. :..: ..  :      : :..  
NP_667 PSASGGAAAAAAAPAAPAAPRSRSLGGAVGSVASGARAAQSPFSIPNSSSGPYGSQDSVH
       60        70        80        90       100       110        

              110        120       130       140       150         
pF1KB8 ------GGGHHRD-GMLYLGSRASLADALPLHIAPRWFSSHSGFKCPICSKSVASDEMEM
             :::. :  :    : :  .. .:: :..:. :.   :::::.::: :.::::..
NP_667 SSPEDGGGGRDRPVGGSPGGPRLVIG-SLPAHLSPHMFG---GFKCPVCSKFVSSDEMDL
      120       130       140        150          160       170    

     160       170       180       190       200       210         
pF1KB8 HFIMCLSKPRLSYNDDVLTKDAGECVICLEELLQGDTIARLPCLCIYHKSCIDSWFEVNR
       :..:::.:::..::.:::.::::::.:::::: ::::::::::::::::.::: ::::::
NP_667 HLVMCLTKPRITYNEDVLSKDAGECAICLEELQQGDTIARLPCLCIYHKGCIDEWFEVNR
          180       190       200       210       220       230    

     220       
pF1KB8 SCPEHPAD
       ::::::.:
NP_667 SCPEHPSD
          240  




227 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Fri Nov  4 12:35:54 2016 done: Fri Nov  4 12:35:55 2016
 Total Scan time:  5.650 Total Display time: -0.040

Function used was FASTA [36.3.4 Apr, 2011]