FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB8407, 294 aa 1>>>pF1KB8407 294 - 294 aa - 294 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.9723+/-0.000769; mu= 7.5919+/- 0.046 mean_var=106.0075+/-22.813, 0's: 0 Z-trim(110.0): 45 B-trim: 0 in 0/54 Lambda= 0.124568 statistics sampled from 11249 (11269) to 11249 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.718), E-opt: 0.2 (0.346), width: 16 Scan time: 2.060 The best scores are: opt bits E(32554) CCDS4409.1 ZNF346 gene_id:23567|Hs108|chr5 ( 294) 1988 367.5 6.4e-102 CCDS78094.1 ZNF346 gene_id:23567|Hs108|chr5 ( 319) 1596 297.1 1.1e-80 CCDS83052.1 ZNF346 gene_id:23567|Hs108|chr5 ( 262) 1161 218.9 3.2e-57 CCDS83053.1 ZNF346 gene_id:23567|Hs108|chr5 ( 196) 840 161.2 5.7e-40 CCDS83054.1 ZNF346 gene_id:23567|Hs108|chr5 ( 118) 404 82.7 1.4e-16 CCDS47848.1 ZMAT4 gene_id:79698|Hs108|chr8 ( 153) 380 78.4 3.6e-15 CCDS34885.1 ZMAT4 gene_id:79698|Hs108|chr8 ( 229) 340 71.3 7.4e-13 CCDS35348.1 ZMAT1 gene_id:84460|Hs108|chrX ( 638) 339 71.3 2e-12 >>CCDS4409.1 ZNF346 gene_id:23567|Hs108|chr5 (294 aa) initn: 1988 init1: 1988 opt: 1988 Z-score: 1943.3 bits: 367.5 E(32554): 6.4e-102 Smith-Waterman score: 1988; 99.7% identity (100.0% similar) in 294 aa overlap (1-294:1-294) 10 20 30 40 50 60 pF1KB8 MEYPAPATVQAADGGAAGPYSSSELLEGQEPDGVRFDRERARRLWEAVSGAQPVGREEVE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 MEYPAPATVQAADGGAAGPYSSSELLEGQEPDGVRFDRERARRLWEAVSGAQPVGREEVE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 HMIQKNQCLFTNTQCKVCCALLISESQKLAHYQSKKHANKVKRYLAIHGMETLKGETKKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 HMIQKNQCLFTNTQCKVCCALLISESQKLAHYQSKKHANKVKRYLAIHGMETLKGETKKL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 DSDQKSSRSKDKNQCCPICNMTFSSPVVAQSYYLGKTHAKNLKLKQQSTKVEALHQNREM :::::::::::::::::::::::::::::::.:::::::::::::::::::::::::::: CCDS44 DSDQKSSRSKDKNQCCPICNMTFSSPVVAQSHYLGKTHAKNLKLKQQSTKVEALHQNREM 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 IDPDKFCSLCHATFNDPVMAQQHYVGKKHRKQETKLKLMARYGRLADPAVTDFPAGKGYP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 IDPDKFCSLCHATFNDPVMAQQHYVGKKHRKQETKLKLMARYGRLADPAVTDFPAGKGYP 190 200 210 220 230 240 250 260 270 280 290 pF1KB8 CKTCKIVLNSIEQYQAHVSGFKHKNQSPKTVASSLGQIPMQRQPIQKDSTTLED :::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 CKTCKIVLNSIEQYQAHVSGFKHKNQSPKTVASSLGQIPMQRQPIQKDSTTLED 250 260 270 280 290 >>CCDS78094.1 ZNF346 gene_id:23567|Hs108|chr5 (319 aa) initn: 1976 init1: 1596 opt: 1596 Z-score: 1562.0 bits: 297.1 E(32554): 1.1e-80 Smith-Waterman score: 1928; 91.8% identity (92.2% similar) in 319 aa overlap (1-294:1-319) 10 20 30 40 50 pF1KB8 MEYPAPATVQAADGGAAGPYSSSELLEGQEPDGVRFDRERARRLWEAVSGAQPVGREE-- :::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS78 MEYPAPATVQAADGGAAGPYSSSELLEGQEPDGVRFDRERARRLWEAVSGAQPVGREEAQ 10 20 30 40 50 60 60 70 80 90 pF1KB8 -----------------------VEHMIQKNQCLFTNTQCKVCCALLISESQKLAHYQSK ::::::::::::::::::::::::::::::::::::: CCDS78 FFPHSRTVIPILVLSETYSLCHPVEHMIQKNQCLFTNTQCKVCCALLISESQKLAHYQSK 70 80 90 100 110 120 100 110 120 130 140 150 pF1KB8 KHANKVKRYLAIHGMETLKGETKKLDSDQKSSRSKDKNQCCPICNMTFSSPVVAQSYYLG ::::::::::::::::::::::::::::::::::::::::::::::::::::::::.::: CCDS78 KHANKVKRYLAIHGMETLKGETKKLDSDQKSSRSKDKNQCCPICNMTFSSPVVAQSHYLG 130 140 150 160 170 180 160 170 180 190 200 210 pF1KB8 KTHAKNLKLKQQSTKVEALHQNREMIDPDKFCSLCHATFNDPVMAQQHYVGKKHRKQETK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS78 KTHAKNLKLKQQSTKVEALHQNREMIDPDKFCSLCHATFNDPVMAQQHYVGKKHRKQETK 190 200 210 220 230 240 220 230 240 250 260 270 pF1KB8 LKLMARYGRLADPAVTDFPAGKGYPCKTCKIVLNSIEQYQAHVSGFKHKNQSPKTVASSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS78 LKLMARYGRLADPAVTDFPAGKGYPCKTCKIVLNSIEQYQAHVSGFKHKNQSPKTVASSL 250 260 270 280 290 300 280 290 pF1KB8 GQIPMQRQPIQKDSTTLED ::::::::::::::::::: CCDS78 GQIPMQRQPIQKDSTTLED 310 >>CCDS83052.1 ZNF346 gene_id:23567|Hs108|chr5 (262 aa) initn: 1151 init1: 1151 opt: 1161 Z-score: 1140.8 bits: 218.9 E(32554): 3.2e-57 Smith-Waterman score: 1711; 88.8% identity (89.1% similar) in 294 aa overlap (1-294:1-262) 10 20 30 40 50 60 pF1KB8 MEYPAPATVQAADGGAAGPYSSSELLEGQEPDGVRFDRERARRLWEAVSGAQPVGREEVE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS83 MEYPAPATVQAADGGAAGPYSSSELLEGQEPDGVRFDRERARRLWEAVSGAQPVGREEVE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 HMIQKNQCLFTNTQCKVCCALLISESQKLAHYQSKKHANKVKRYLAIHGMETLKGETKKL :::::::::::::::::::::::::::::::::: CCDS83 HMIQKNQCLFTNTQCKVCCALLISESQKLAHYQS-------------------------- 70 80 90 130 140 150 160 170 180 pF1KB8 DSDQKSSRSKDKNQCCPICNMTFSSPVVAQSYYLGKTHAKNLKLKQQSTKVEALHQNREM :::::::::::::::::::::::::.:::::::::::::::::::::::::::: CCDS83 ------SRSKDKNQCCPICNMTFSSPVVAQSHYLGKTHAKNLKLKQQSTKVEALHQNREM 100 110 120 130 140 190 200 210 220 230 240 pF1KB8 IDPDKFCSLCHATFNDPVMAQQHYVGKKHRKQETKLKLMARYGRLADPAVTDFPAGKGYP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS83 IDPDKFCSLCHATFNDPVMAQQHYVGKKHRKQETKLKLMARYGRLADPAVTDFPAGKGYP 150 160 170 180 190 200 250 260 270 280 290 pF1KB8 CKTCKIVLNSIEQYQAHVSGFKHKNQSPKTVASSLGQIPMQRQPIQKDSTTLED :::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS83 CKTCKIVLNSIEQYQAHVSGFKHKNQSPKTVASSLGQIPMQRQPIQKDSTTLED 210 220 230 240 250 260 >>CCDS83053.1 ZNF346 gene_id:23567|Hs108|chr5 (196 aa) initn: 1219 init1: 840 opt: 840 Z-score: 831.0 bits: 161.2 E(32554): 5.7e-40 Smith-Waterman score: 1036; 63.3% identity (65.3% similar) in 294 aa overlap (1-294:1-196) 10 20 30 40 50 60 pF1KB8 MEYPAPATVQAADGGAAGPYSSSELLEGQEPDGVRFDRERARRLWEAVSGAQPVGREEVE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS83 MEYPAPATVQAADGGAAGPYSSSELLEGQEPDGVRFDRERARRLWEAVSGAQPVGREE-- 10 20 30 40 50 70 80 90 100 110 120 pF1KB8 HMIQKNQCLFTNTQCKVCCALLISESQKLAHYQSKKHANKVKRYLAIHGMETLKGETKKL :: .:.: CCDS83 -------------------AL-----------------------------------SKRL 60 130 140 150 160 170 180 pF1KB8 DSDQKSSRSKDKNQCCPICNMTFSSPVVAQSYYLGKTHAKNLKLKQQSTKVEALHQNREM ..: .. : :::::::: CCDS83 -----------------------TNPFLVASTL-------------------ALHQNREM 70 80 190 200 210 220 230 240 pF1KB8 IDPDKFCSLCHATFNDPVMAQQHYVGKKHRKQETKLKLMARYGRLADPAVTDFPAGKGYP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS83 IDPDKFCSLCHATFNDPVMAQQHYVGKKHRKQETKLKLMARYGRLADPAVTDFPAGKGYP 90 100 110 120 130 140 250 260 270 280 290 pF1KB8 CKTCKIVLNSIEQYQAHVSGFKHKNQSPKTVASSLGQIPMQRQPIQKDSTTLED :::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS83 CKTCKIVLNSIEQYQAHVSGFKHKNQSPKTVASSLGQIPMQRQPIQKDSTTLED 150 160 170 180 190 >>CCDS83054.1 ZNF346 gene_id:23567|Hs108|chr5 (118 aa) initn: 782 init1: 404 opt: 404 Z-score: 411.0 bits: 82.7 E(32554): 1.4e-16 Smith-Waterman score: 434; 40.1% identity (40.1% similar) in 294 aa overlap (1-294:1-118) 10 20 30 40 50 60 pF1KB8 MEYPAPATVQAADGGAAGPYSSSELLEGQEPDGVRFDRERARRLWEAVSGAQPVGREEVE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS83 MEYPAPATVQAADGGAAGPYSSSELLEGQEPDGVRFDRERARRLWEAVSGAQPVGREE-- 10 20 30 40 50 70 80 90 100 110 120 pF1KB8 HMIQKNQCLFTNTQCKVCCALLISESQKLAHYQSKKHANKVKRYLAIHGMETLKGETKKL CCDS83 ------------------------------------------------------------ 130 140 150 160 170 180 pF1KB8 DSDQKSSRSKDKNQCCPICNMTFSSPVVAQSYYLGKTHAKNLKLKQQSTKVEALHQNREM CCDS83 ------------------------------------------------------------ 190 200 210 220 230 240 pF1KB8 IDPDKFCSLCHATFNDPVMAQQHYVGKKHRKQETKLKLMARYGRLADPAVTDFPAGKGYP :::::: CCDS83 ------------------------------------------------------AGKGYP 60 250 260 270 280 290 pF1KB8 CKTCKIVLNSIEQYQAHVSGFKHKNQSPKTVASSLGQIPMQRQPIQKDSTTLED :::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS83 CKTCKIVLNSIEQYQAHVSGFKHKNQSPKTVASSLGQIPMQRQPIQKDSTTLED 70 80 90 100 110 >>CCDS47848.1 ZMAT4 gene_id:79698|Hs108|chr8 (153 aa) initn: 400 init1: 331 opt: 380 Z-score: 385.9 bits: 78.4 E(32554): 3.6e-15 Smith-Waterman score: 380; 42.3% identity (68.6% similar) in 156 aa overlap (66-217:7-151) 40 50 60 70 80 90 pF1KB8 FDRERARRLWEAVSGAQPVGREEVEHMIQKNQCLFTNTQCKVCCALLISESQKLAHYQSK .: :::.. :::: : ::::::..:::.:. CCDS47 MKSSDIDQDLFTDSYCKVCSAQLISESQRVAHYESR 10 20 30 100 110 120 130 140 150 pF1KB8 KHANKVKRYLAIHGMETLKGETKKLDSDQKSSRSK-DKNQCCPICNMTFSSPVVAQSYYL :::.::. : .: . .:.: :.. :. . :::.:: .:::.:.: :::.:.: CCDS47 KHASKVRLYYMLHPRDG-GCPAKRLRSENGSDADMVDKNKCCTLCNMSFTSAVVADSHYQ 40 50 60 70 80 90 160 170 180 190 200 210 pF1KB8 GKTHAKNLKL---KQQSTKVEALHQNREMIDPDKFCSLCHATFNDPVMAQQHYVGKKHRK :: ::: ::: .. :. .:..: . :..: ...:. . . : :.:: CCDS47 GKIHAKRLKLLLGEKTPLKTTGLRRNYR-------CTICSVSLNSIEQYHAHLKGSKH-- 100 110 120 130 140 220 230 240 250 260 270 pF1KB8 QETKLKLMARYGRLADPAVTDFPAGKGYPCKTCKIVLNSIEQYQAHVSGFKHKNQSPKTV .:.:: CCDS47 -QTNLKNK 150 >>CCDS34885.1 ZMAT4 gene_id:79698|Hs108|chr8 (229 aa) initn: 532 init1: 331 opt: 340 Z-score: 344.3 bits: 71.3 E(32554): 7.4e-13 Smith-Waterman score: 565; 43.4% identity (65.3% similar) in 219 aa overlap (66-264:7-223) 40 50 60 70 80 90 pF1KB8 FDRERARRLWEAVSGAQPVGREEVEHMIQKNQCLFTNTQCKVCCALLISESQKLAHYQSK .: :::.. :::: : ::::::..:::.:. CCDS34 MKSSDIDQDLFTDSYCKVCSAQLISESQRVAHYESR 10 20 30 100 110 120 130 140 150 pF1KB8 KHANKVKRYLAIHGMETLKGETKKLDSDQKSSRSK-DKNQCCPICNMTFSSPVVAQSYYL :::.::. : .: . .:.: :.. :. . :::.:: .:::.:.: :::.:.: CCDS34 KHASKVRLYYMLHPRDG-GCPAKRLRSENGSDADMVDKNKCCTLCNMSFTSAVVADSHYQ 40 50 60 70 80 90 160 170 180 190 pF1KB8 GKTHAKNLKL--------KQQSTKVEALHQNR-----------EMIDPDKFCSLCHATFN :: ::: ::: : .: . :. : . : :..:.:: : :: CCDS34 GKIHAKRLKLLLGEKTPLKTTATPLSPLKPPRMDTAPVVASPYQRRDSDRYCGLCAAWFN 100 110 120 130 140 150 200 210 220 230 240 250 pF1KB8 DPVMAQQHYVGKKHRKQETKLKLMARYGRLADPAVTDFPAGKGYPCKTCKIVLNSIEQYQ .:.:::::: ::::.:. ... :. . : : . ..: : :.. :::::::. CCDS34 NPLMAQQHYDGKKHKKNAARVALLEQLGTTLDMGELR-GLRRNYRCTICSVSLNSIEQYH 160 170 180 190 200 210 260 270 280 290 pF1KB8 AHVSGFKHKNQSPKTVASSLGQIPMQRQPIQKDSTTLED ::..: ::. CCDS34 AHLKGSKHQTNLKNK 220 >>CCDS35348.1 ZMAT1 gene_id:84460|Hs108|chrX (638 aa) initn: 418 init1: 168 opt: 339 Z-score: 336.4 bits: 71.3 E(32554): 2e-12 Smith-Waterman score: 345; 30.0% identity (64.5% similar) in 220 aa overlap (49-252:32-251) 20 30 40 50 60 70 pF1KB8 PYSSSELLEGQEPDGVRFDRERARRLWEAVSGAQPVGREEVEHMIQKNQCLFTNTQCKVC :..: .: .. :.. :::. :.:: CCDS35 ESCSVTRLECSGAISAHCSLHLPGSSDSPASASQIAGTTDAIWNEQEKAELFTDKFCQVC 10 20 30 40 50 60 80 90 100 110 120 130 pF1KB8 CALLISESQKLAHYQSKKHANKVKRYLAIHGMET-LKGETKKLDSDQ-KSSRSK--DKNQ ..: :::...::...:::..:. :. .:: .. . :. :. .. . : . :::. CCDS35 GVMLQFESQRISHYEGEKHAQNVSFYFQMHGEQNEVPGKKMKMHVENFQVHRYEGVDKNK 70 80 90 100 110 120 140 150 160 170 180 190 pF1KB8 CCPICNMTFSSPVVAQSYYLGKTHAKNLK--LKQQSTKVEALHQNREMIDPDKF-CSLCH : .::: ::::..:::.:.::.:::.:: ..... . : . .. . : .: CCDS35 FCDLCNMMFSSPLIAQSHYVGKVHAKKLKQLMEEHDQASPSGFQPEMAFSMRTYVCHICS 130 140 150 160 170 180 200 210 220 230 240 pF1KB8 ATFNDPVMAQQHYVGKKHRKQETKLKLMARYGRLADPAV----TDF---PAGKGYPCKTC .:.. : ..:. :..:. .:. . ... .: .. . .:. ..: ::: CCDS35 IAFTSLDMFRSHMQGSEHQIKESIVINLVKNSRKTQDSYQNECADYINVQKARGLEAKTC 190 200 210 220 230 240 250 260 270 280 290 pF1KB8 --KIVLNSIEQYQAHVSGFKHKNQSPKTVASSLGQIPMQRQPIQKDSTTLED :. .:.: CCDS35 FRKMEESSLETRRYREVVDSRPRHRMFEQRLPFETFRTYAAPYNISQAMEKQLPHSKKTY 250 260 270 280 290 300 294 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 12:40:44 2016 done: Fri Nov 4 12:40:44 2016 Total Scan time: 2.060 Total Display time: -0.010 Function used was FASTA [36.3.4 Apr, 2011]